TWAS hub - C14orf169

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0603	0.0243	1.6e-06	0.003	0.016	0.015	NA	0.009	0.084	0.00024	0.0004	NA	0.0056
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0677	0.0401	6.9e-03	0.005	-0.002	0.003	NA	0.000	0.080	0.69000	0.1400	NA	0.2700
3	TCGA	Lung Adenocarcinoma	0.1011	0.0514	5.2e-04	0.012	0.002	0.001	NA	0.006	0.014	0.18000	0.2100	NA	0.0600
4	TCGA	Stomach Adenocarcinoma	0.0590	0.0300	5.0e-03	0.011	0.015	0.018	NA	0.016	0.047	0.02500	0.0180	NA	0.0220

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Alzheimer’s Disease (in mother)	9.1	10.7	17.4	4.2	1.7	3.1	3.6
Alzheimer’s Disease (including proxy)	7.4	10.7	16.0	3.7	1.3	3.3	4.0
Supplements: Zinc	5.0	5.5	7.9	-2.6	-2.8	-2.2	-1.5
HbA1C	4.4	4.9	6.0	-2.5	-1.9	-2.4	-2.1
Number of operations (self-reported)	4.1	6.1	8.4	2.8	1.7	2.4	2.9
Length of working week for main job	3.7	4.1	5.4	2.3	1.4	2.0	2.2
Supplements: Vitamin C	3.7	4.4	8.3	-2.9	-2.2	-1.8	-1.1
Qualifications: CSEs or equivalent	3.5	4.7	9.7	-1.8	-0.1	-2.3	-3.1
Alzheimer’s Disease (in father)	3.4	3.7	5.5	1.9	1.4	2.3	1.9
Townsend deprivation index at recruitment	3.0	4.3	6.4	2.2	0.8	2.3	2.5
Bipolar Disorder (2011)	2.7	2.6	3.0	-1.6	-1.7	-1.4	-1.7
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	5.6	-1.1	-2.2	-2.4	-1.0
Hand grip strength (right)	2.4	6.5	10.5	-2.3	-0.7	-3.1	-3.2
Ever had hysterectomy (womb removed)	2.2	2.5	4.4	2.1	1.4	1.3	1.2
Schizophrenia (2018)	2.1	4.3	8.6	-2.9	-1.9	-1.3	-1.8
Blood Platelet Count	2.1	24.7	38.4	-5.8	-2.0	-4.8	-6.2
Suffer from ‘nerves’	2.0	3.1	8.9	-1.7	-3.0	-0.4	0.5
Current tobacco smoking	1.9	3.2	6.7	1.6	0.9	1.6	2.6
Had other major operations	1.9	2.3	3.4	1.7	0.5	1.6	1.8
Number of incorrect matches in round	1.8	3.0	4.3	1.9	1.2	1.6	2.1
Hearing aid user	1.8	2.0	2.4	1.3	1.3	1.5	1.5
Medication: Bendroflumethiazide	1.8	2.8	6.2	-1.2	-1.2	-2.5	-1.4
Medication: Lisinopril	1.8	2.4	4.4	2.1	1.6	1.2	1.0
Pain experienced in last month	1.8	3.0	6.1	0.8	-0.5	2.3	2.5
Worry too long after embarrassment	1.7	2.9	4.5	1.7	1.8	2.1	1.0
Diabetes (self-reported)	1.6	2.5	4.6	2.2	1.3	1.3	1.4
Heart disease (siblings)	1.6	1.9	2.6	-1.6	-0.9	-1.6	-1.4
Major Depression (MDD)	1.5	1.9	3.1	1.5	0.8	1.8	1.2
Medication: Atenolol	1.5	1.9	4.0	-0.2	-0.3	-1.9	-2.0
Smoking status: Previous	1.5	2.2	5.2	-1.3	-0.6	-2.3	-1.2
Medication: Paracetamol	1.5	2.4	4.9	-1.6	-0.5	-2.2	-1.4
Illnesses of father: High blood pressure	1.5	1.9	2.8	-1.4	-1.7	-1.4	-1.0
Maternal smoking around birth	1.4	2.0	4.2	2.1	0.9	1.2	1.2
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	2.9	-1.7	-1.4	-1.3	-0.9
Father’s age at death	1.4	1.9	4.4	0.5	0.1	2.1	1.7
Migraine (self-reported)	1.4	1.7	2.6	-1.5	-1.6	-1.4	-0.4
Number of full sisters	1.4	1.7	2.6	1.4	1.6	0.9	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	2.4	-1.6	-1.2	-1.2	-1.2
Illnesses of father: Heart disease	1.4	1.9	2.5	-1.4	-1.6	-1.3	-1.2
Schizophrenia (2014)	1.3	2.9	5.5	-2.4	-0.8	-1.0	-2.1
Chronotype (morning person)	1.3	2.9	6.0	-1.4	-0.6	-1.8	-2.5
Alcohol usually taken with meals	1.3	2.1	2.8	-1.5	-1.3	-1.3	-1.7
Time employed in main current job	1.3	1.5	3.1	-0.7	0.3	-1.8	-1.5
Medication: Paracetamol	1.3	2.2	6.0	-1.3	-0.4	-2.5	-0.9
Headache pain in last month	1.3	2.2	3.5	-1.5	-1.5	-1.9	-0.8
Medication: Allopurinol	1.3	1.8	2.8	1.5	0.4	1.3	1.7
Smoking status: Current	1.3	2.0	4.9	1.2	0.6	1.2	2.2
Ever depressed for a whole week	1.3	1.6	2.2	-1.4	-1.3	-1.5	-0.5
Chronic bronchitis/emphysema (father)	1.2	1.4	3.2	-0.6	-0.4	-1.4	-1.8
Illnesses of siblings: Diabetes	1.2	1.4	1.9	1.4	0.9	1.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.9	1.8	0.6	1.3	2.2
Schizophrenia vs Biploar Disorder	1.1	1.5	3.1	-1.4	-0.3	-0.8	-1.8
Fasting Glucose	1.1	1.3	2.0	-1.4	-1.4	-1.1	-0.4
Angina	1.1	1.4	2.8	-1.1	0.2	-1.7	-1.3
High blood pressure (mother)	1.1	1.5	4.4	-0.6	0.1	-1.1	-2.1
Medication: Ramipril	1.1	1.4	2.8	-0.7	-0.3	-1.5	-1.7
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.1	1.1	1.4	1.4	0.1
Depression (self-reported)	1.1	1.3	1.7	1.3	0.8	1.2	1.1
Exposure to tobacco smoke outside home	1.1	1.5	2.5	1.2	-0.2	1.5	1.6
Chest pain or discomfort	1.1	1.6	1.7	-1.3	-1.3	-1.1	-1.3
Commuting to job workplace: Car/motor vehicle	1.1	1.3	1.9	-1.4	-1.2	-1.2	-0.4
Ulcerative Colitis (UC)	1.0	1.9	3.0	-1.3	-1.0	-1.4	-1.7
Hand grip strength (left)	1.0	2.6	5.5	-1.1	-0.2	-1.9	-2.4
Relative age of first facial hair	1.0	2.0	5.9	-2.4	-1.3	-0.5	-0.5
Hearing difficulty/problems with background noise	1.0	1.5	3.0	1.7	0.1	-0.3	1.7
Tense / ‘highly strung’	1.0	1.7	5.1	-0.8	-2.3	-1.0	0.2
Gout (self-reported)	1.0	1.4	2.7	1.2	-0.1	1.1	1.6
Angina (self-reported)	1.0	1.3	2.5	-0.9	0.5	-1.6	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.1	2.7	-1.7	-0.6	-0.9	-0.8
Commuting to job workplace: Walk	1.0	1.1	3.2	-0.9	-1.8	-0.4	-0.4
Breast cancer (self-reported)	1.0	1.2	2.3	1.0	0.5	1.5	1.2
Bipolar Disorder or Schizophrenia	0.9	2.2	4.3	-2.1	-1.3	-0.9	-1.4
Verbal and Numeric Reasoning (VNR)	0.9	2.1	4.0	1.4	-0.1	1.6	2.0
Type 2 Diabetes (T2D) (2018)	0.9	1.6	2.6	1.6	0.9	0.9	1.5
Average weekly fortified wine intake	0.9	1.1	3.3	-0.8	-1.8	0.2	-0.6
Exposure to tobacco smoke at home	0.9	1.0	1.9	-1.2	-1.4	-0.6	-0.7
Blood clot in the leg (DVT)	0.9	1.2	2.8	0.5	0.7	1.1	1.7
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.0	1.0	1.4	1.2	0.5
Wheeze or whistling in the chest in last year	0.9	1.6	1.8	-1.4	-1.1	-1.2	-1.4
Knee pain experienced in last month	0.9	1.4	3.4	-0.7	-0.5	-1.9	-1.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.0	-0.6	-1.4	-0.8	1.2
Illnesses of father: None of the above (group 1)	0.9	1.2	1.7	1.1	0.7	1.3	1.1
Mother’s age at death	0.9	1.1	1.4	1.1	1.0	0.9	1.2
Worry (Nagel 2018)	0.8	1.8	5.2	-1.4	-2.3	-0.0	0.1
Rheumatoid Arthritis	0.8	1.1	2.3	-0.1	-1.5	0.4	1.4
Supplements: Glucosamine	0.8	1.1	2.9	0.8	1.7	-0.7	-0.5
Past tobacco smoking	0.8	1.5	4.5	0.9	0.4	2.1	0.7
Illnesses of mother	0.8	1.0	1.7	-1.1	-1.3	-0.7	-0.7
Loud music exposure frequency	0.8	0.9	3.1	-0.3	-1.8	-0.2	0.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.6	-1.2	-0.2	-0.5	-1.6
Forced vital capacity (FVC), Best measure	0.8	2.8	5.2	2.2	0.6	1.0	2.3
Number of children fathered	0.8	0.9	2.1	1.1	0.7	-0.1	-1.4
Heart disease (mother)	0.8	1.0	2.7	0.9	0.6	0.2	1.6
Had major operations	0.8	0.9	1.5	1.2	0.8	0.5	1.1
Diabetes diagnosed by doctor	0.8	1.4	2.5	1.6	1.1	0.8	1.1
Osteoarthritis (self-reported)	0.8	1.1	2.0	1.4	0.8	0.4	1.2
Wears glasses or contact lenses	0.8	0.9	2.5	-0.5	0.3	-0.9	-1.6
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.5	0.6	-0.0	-1.9	0.1
Irritable Bowel Disease (IBD)	0.7	1.6	2.7	-1.1	-0.4	-1.5	-1.6
Cardiovascular Disease	0.7	2.5	6.7	-0.5	-0.2	-2.6	-1.7
Average weekly spirits intake	0.7	0.9	1.8	1.1	1.3	0.5	-0.6
Nervous feelings	0.7	1.3	3.2	-1.3	-1.8	0.2	-0.1
Hair/balding pattern: Pattern 3	0.7	1.1	1.8	-0.3	1.3	-0.9	-1.2
Qualifications: A levels/AS levels or equivalent	0.7	1.6	3.9	-1.5	-2.0	-0.4	-0.2
Medication: Cholesterol lowering	0.7	1.0	1.9	0.9	1.1	-1.4	-0.6
Prospective memory result	0.7	0.8	2.6	0.2	0.5	0.6	1.6
Impedance of arm (left)	0.7	3.3	6.0	1.1	-0.2	2.4	2.4
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.9	-0.0	1.4	-0.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	-0.5	-0.6	-1.0	-1.3
Medication: Aspirin	0.7	0.9	2.2	0.2	0.3	-1.5	-1.1
Friendships satisfaction	0.7	0.9	1.6	0.4	-1.0	0.9	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.5	1.2	0.3	0.6	1.2
Osteoporosis (self-reported)	0.7	0.9	2.4	0.5	0.4	1.6	0.8
Guilty feelings	0.7	1.0	1.2	-1.1	-1.0	-0.9	-1.0
Depressed Affect (Nagel 2018)	0.6	1.3	3.0	-1.7	-0.7	-0.7	-1.1
Lupus	0.6	1.0	1.2	1.1	0.7	1.0	1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.2	1.0	1.1	-0.1	-0.6
BMI	0.6	3.8	6.6	-1.3	-1.0	-2.4	-2.6
Systolic Blood Pressure	0.6	3.0	7.8	-1.0	-0.5	-1.7	-2.8
Lung FEV1/FVC ratio	0.6	3.2	5.4	-2.3	-1.1	-1.7	-1.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.3	0.7	-0.2	1.2	1.2
Hearing difficulty/problems: Yes	0.6	1.0	2.5	1.6	0.1	-0.0	1.2
Systolic blood pressure, automated reading	0.6	1.9	5.4	-0.6	0.1	-1.3	-2.3
Medication: Levothyroxine sodium	0.6	1.1	3.3	-1.8	0.1	-0.6	-0.8
Had menopause	0.6	0.8	1.8	0.5	1.4	0.6	-0.8
Forced vital capacity (FVC)	0.6	2.2	4.2	1.7	0.7	1.1	2.1
Pain all over the body in last month	0.6	0.6	1.2	-0.2	1.1	-0.4	-1.1
Impedance of arm (right)	0.6	2.7	5.3	1.1	0.1	2.0	2.3
Mouth/teeth dental problems: Dentures	0.6	1.0	2.9	0.8	-0.0	0.7	1.7
Medication: Lansoprazole	0.6	0.6	1.0	-0.0	-1.0	-0.8	1.0
Pulse wave reflection index	0.6	0.7	1.0	-1.0	0.3	-0.9	-1.0
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.0	-0.9	-0.9	1.4	0.7
Shortness of breath walking on level ground	0.6	0.8	1.5	-0.8	-1.2	-1.0	-0.1
Medication: Blood pressure	0.6	1.1	2.0	-0.3	-1.0	-1.4	-1.1
Average weekly beer plus cider intake	0.6	0.9	2.0	0.9	1.4	-0.8	-0.6
Unable to work because of sickness or disability	0.6	0.7	1.8	1.0	0.2	0.3	1.4
Supplements: Calcium	0.6	0.7	1.3	-0.5	0.8	-0.6	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.7	0.3	0.9	0.8	1.3
Reaction Time	0.5	1.0	2.2	1.5	-0.0	1.1	0.8
Body Mass Index (BMI) (2010)	0.5	0.7	1.1	-1.0	-0.7	-1.0	-0.5
Coronary Artery Disease (CAD)	0.5	0.6	1.0	-0.9	0.1	-0.9	-1.0
HDL Cholesterol	0.5	0.8	1.5	1.2	0.8	0.9	0.4
Ulcerative Colitis	0.5	0.7	1.9	-0.3	-0.7	-0.6	-1.4
Medication for hormone replacement therapy	0.5	0.6	1.9	0.0	0.2	-0.7	-1.4
Severe depression (siblings)	0.5	0.6	1.5	0.3	-1.2	0.4	0.8
Worrier / anxious feelings	0.5	1.0	3.6	-0.7	-1.9	0.1	-0.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.1	-0.4	-1.4	0.2	0.5
Glaucoma (self-reported)	0.5	0.5	1.6	0.6	-0.4	0.1	1.3
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.2	-1.5	0.1	-1.0	-0.6
Medication: Amlodipine	0.5	0.7	1.4	0.1	0.2	-1.2	-1.1
Leg fat percentage (right)	0.5	1.6	3.2	-0.3	-0.5	-1.8	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.3	-0.0	-0.7	0.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.6	-0.1	0.6	-0.7	-1.2
Health satisfaction	0.5	0.7	0.9	-0.7	-0.9	-0.8	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.3	0.1	-0.2	1.5	0.2
Medication: Blood pressure	0.5	0.8	1.9	0.8	0.7	-1.4	-0.5
Mean time to correctly identify matches	0.5	1.0	2.4	1.5	0.6	0.7	0.9
Comparative height size at age 10	0.5	3.0	6.5	1.7	0.2	1.5	2.5
Age at last live birth	0.5	0.7	1.2	0.4	0.8	1.1	0.9
Qualifications: nursing, teaching	0.5	0.8	1.8	0.5	-0.8	0.8	1.4
Back pain experienced in last month	0.5	0.8	2.0	0.7	1.4	0.2	-0.6
Commuting to job workplace: Cycle	0.5	0.6	1.5	-0.4	-0.8	-1.2	-0.2
Cholesterol lowering medication	0.5	0.8	1.5	1.0	1.2	0.8	0.3
Neuroticism (Nagel 2018)	0.4	0.9	1.8	-1.3	-1.4	0.2	0.1
Breast Cancer	0.4	0.9	1.5	-1.2	-0.8	-0.7	-1.0
Ovarian Cancer	0.4	0.6	1.1	0.8	0.5	1.0	0.5
Allergy or Eczema	0.4	0.9	2.7	-0.5	-0.7	-0.5	-1.6
Respiratory disease	0.4	0.8	1.8	0.6	1.3	0.3	-1.0
Medication: Co-codamol	0.4	0.5	0.9	0.5	0.9	-0.9	-0.2
Pack years adult smoking proportion	0.4	0.6	1.4	1.2	-0.1	0.8	0.7
Fed-up feelings	0.4	0.7	2.0	-0.5	0.1	-0.7	-1.4
Stomach or abdominal pain in last month	0.4	0.5	0.7	-0.6	-0.8	-0.7	-0.8
Body mass index (BMI)	0.4	1.8	3.1	-0.8	-0.8	-1.7	-1.8
Qualifications: None of the above	0.4	0.9	1.6	-0.8	-0.0	-1.2	-1.3
Fluid intelligence score	0.4	0.7	1.0	1.0	0.1	0.9	1.0
Illnesses of siblings	0.4	0.6	1.3	0.3	0.3	1.2	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	2.7	1.4	0.3	0.8	1.7
Breastfed as a baby	0.4	0.5	1.8	0.1	0.1	0.4	1.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.4	-0.6	-1.2	0.9	0.5
Medication: Seretide 50 evohaler	0.4	0.4	0.7	0.8	0.6	0.8	-0.1
Mineral and other dietary supplements	0.4	0.6	1.2	-0.2	-0.9	1.1	0.4
Medication: Aspirin	0.4	0.6	0.9	0.7	0.6	-1.0	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	0.9	0.7	0.7	1.0	-0.3
Financial situation satisfaction	0.4	0.5	0.9	-0.8	0.5	-0.7	-0.9
Medication: Atorvastatin	0.4	0.5	1.5	0.7	1.2	0.2	0.2
Alcohol drinker status: Never	0.4	0.5	0.9	-0.9	-0.9	0.5	0.4
Leg fat percentage (left)	0.4	1.6	3.2	-0.3	-0.5	-1.6	-1.8
Fractured/broken bones in last 5 years	0.4	0.6	0.9	-0.9	-1.0	-0.0	0.7
Age started oral contraceptive pill	0.4	0.5	1.3	-1.1	-0.3	-0.1	-0.8
Prostate Cancer	0.3	0.5	0.9	-0.1	-1.0	-0.5	0.9
LDL Cholesterol	0.3	0.4	1.1	-0.1	-0.7	0.1	1.1
Neuroticism (2016)	0.3	0.4	1.0	-0.7	-0.0	-0.3	-1.0
Triglycerides	0.3	0.5	0.5	0.7	0.6	0.7	0.7
Blood Red Count	0.3	2.9	9.5	-1.3	-0.4	-0.5	-3.1
Smoking Status	0.3	0.8	2.2	0.1	-1.0	-0.3	1.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	-0.0	0.1	-0.7	0.9
Medication: Metformin	0.3	0.4	1.0	1.0	0.8	-0.4	0.1
Age when periods started (menarche)	0.3	0.7	2.3	-0.3	-0.4	0.3	1.5
High blood pressure	0.3	0.7	2.2	-0.1	-0.4	-1.5	-0.8
Sitting height	0.3	2.4	7.3	2.7	0.9	0.9	0.9
Impedance of leg (left)	0.3	1.4	2.8	1.2	0.7	1.7	1.0
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.8	-0.5	-0.2	-0.9	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.2	0.7	0.0	1.1	0.7
Standing height	0.3	2.5	4.8	1.9	0.3	1.3	2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.7	-1.0	-0.4	0.5
Number of full brothers	0.3	0.4	0.8	0.6	0.6	-0.3	0.9
Pulse wave peak to peak time	0.3	0.3	0.8	-0.0	-0.7	-0.1	0.9
Qualifications: College or University degree	0.3	1.0	2.2	0.9	-0.1	0.8	1.5
Emphysema/chronic bronchitis	0.3	0.3	0.6	-0.4	0.6	-0.2	-0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	1.6	-0.0	0.2	1.3	0.5
Neck or shoulder pain in last month	0.3	0.5	0.7	-0.8	-0.8	-0.7	-0.3
Medication: Ibuprofen	0.3	0.3	0.9	-0.6	-1.0	-0.1	-0.1
Leg fat mass (right)	0.3	1.3	2.8	-0.2	-0.7	-1.7	-1.4
Family relationship satisfaction	0.3	0.3	0.6	0.4	0.1	0.8	0.8
Hypertension (Self-reported)	0.3	0.8	2.4	0.3	0.2	-1.6	-0.9
Long-standing illness, disability or infirmity	0.3	0.5	1.1	-0.1	1.0	-0.4	-0.9
Ever had bowel cancer screening	0.3	0.4	0.9	0.2	-0.6	0.4	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.7	0.1	0.8	-0.1	-0.6
Medication for cholesterol	0.3	0.5	1.2	-1.1	-0.4	0.5	0.6
Medication: Gliclazide	0.3	0.3	0.6	0.8	0.5	-0.6	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.5	-0.4	-0.8	-1.2	0.0
Miserableness	0.3	0.6	1.4	-1.2	-0.4	-0.6	-0.6
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.6	-0.6	-0.7	-0.8	-0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	0.6	1.1	-0.4	-0.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	1.1	0.4	0.3	-0.0
Basal cell carcinoma (self-reported)	0.3	0.4	1.0	1.0	0.5	0.1	0.5
Pack years of smoking	0.3	0.5	1.1	1.0	-0.1	0.6	0.6
Impedance of whole body	0.3	1.5	3.3	0.8	0.0	1.8	1.4
Leg fat mass (left)	0.3	1.2	2.4	-0.2	-0.6	-1.5	-1.4
Crohns Disease (2017)	0.2	0.3	0.6	-0.5	-0.1	-0.8	-0.7
Age at First Birth	0.2	0.3	0.6	-0.2	0.8	-0.6	-0.3
Primary Biliary Cirrhosis	0.2	0.2	0.4	-0.4	-0.6	0.0	-0.6
Blood White Count	0.2	1.6	3.1	1.3	-0.7	1.0	1.8
Heel T-Score	0.2	1.5	2.5	1.1	-0.2	1.6	1.5
Height	0.2	3.5	7.5	2.4	0.1	0.8	2.7
Lung FVC	0.2	1.2	1.8	1.4	0.4	1.1	1.2
Number of treatments/medications taken	0.2	0.3	1.2	0.1	-0.2	-1.1	-0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.7	-0.8	0.3	-0.1	-0.3
Diabetes (father)	0.2	0.3	0.6	-0.8	-0.5	0.1	-0.4
Impedance of leg (right)	0.2	1.1	1.9	1.1	0.8	1.4	0.8
Relative age voice broke	0.2	0.3	0.8	-0.9	-0.6	0.2	-0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.6	-0.5	-0.2	-0.3	-0.8
Serious illness, injury or assault to yourself	0.2	0.2	0.5	-0.0	0.7	-0.4	0.4
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	-0.5	-0.5	-0.5	-1.2
Multivitamins +/- minerals	0.2	0.3	0.5	0.4	0.1	0.7	0.7
Waist circumference	0.2	0.6	1.0	-0.4	-1.0	-0.9	-0.7
Hair/balding pattern: Pattern 2	0.2	0.2	0.8	-0.1	-0.0	0.9	0.0
Financial difficulties in last 2 years	0.2	0.3	0.5	-0.1	0.7	0.6	-0.5
Mouth/teeth dental problems	0.2	0.3	0.5	-0.4	0.4	-0.7	-0.7
Heart attack	0.2	0.3	0.5	-0.5	-0.4	-0.7	-0.5
Number of live births	0.2	0.2	0.5	0.5	0.4	0.7	0.3
Happiness	0.2	0.3	0.7	-0.1	-0.8	-0.2	0.7
Noisy workplace	0.2	0.2	0.5	0.2	0.5	-0.7	-0.4
Birth weight	0.2	0.3	0.9	-0.6	-0.9	0.1	0.3
High blood pressure (siblings)	0.2	0.2	0.6	0.5	-0.2	-0.8	-0.3
Age at first live birth	0.2	0.3	0.9	-0.3	0.9	-0.3	-0.3
Medication: Omeprazole	0.2	0.2	0.4	0.0	0.3	-0.6	-0.6
Leg pain on walking	0.2	0.2	0.5	-0.4	-0.5	-0.7	0.1
Average weekly red wine intake	0.2	0.3	0.8	0.2	-0.7	-0.9	-0.2
Mood swings	0.2	0.3	0.7	-0.4	0.2	-0.5	-0.8
Loneliness, isolation	0.2	0.3	0.7	-0.6	-0.8	-0.1	0.4
Arm fat mass (left)	0.2	0.7	1.4	-0.1	-0.8	-1.2	-0.9
Commuting to job workplace: Public transport	0.2	0.2	0.4	-0.2	0.6	0.6	0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	0.2	-0.5	-0.3	0.6
High cholesterol (Self-reported)	0.2	0.4	1.2	0.1	0.2	-1.1	-0.5
Ever smoked	0.2	0.4	1.1	-0.2	-0.6	-1.1	0.5
Irritability	0.2	0.4	1.0	0.4	-0.5	0.3	1.0
Risk taking	0.2	0.3	0.9	0.6	1.0	-0.1	-0.2
Diastolic blood pressure, automated reading	0.2	0.6	1.9	-0.1	-0.3	-0.6	-1.4
Myopia	0.2	0.3	0.7	0.2	0.3	0.8	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.8	0.3	0.5	1.3	0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.5	-0.3	-0.3	-0.7	-0.6
Arm predicted mass (left)	0.2	1.0	2.5	-0.1	-0.2	-1.6	-1.1
Depression (Nagel 2018)	0.1	0.2	0.5	-0.5	-0.7	0.1	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.7	0.2	-0.9	-0.4	0.6
Crohns Disease (2012)	0.1	0.1	0.2	0.2	0.2	-0.5	-0.4
Mean Putamen Volume	0.1	0.1	0.1	0.4	0.1	0.1	0.3
Waist Hip Ratio (WHR)	0.1	0.2	0.6	-0.5	-0.2	-0.0	0.8
Hypothyroidism (self reported)	0.1	0.2	0.5	-0.7	0.5	-0.1	0.5
Neuroticism	0.1	0.1	0.3	-0.3	-0.5	0.4	-0.2
Hair Pigment	0.1	3.2	4.8	-1.9	-0.9	-1.9	-2.2
Tanning	0.1	1.1	1.7	-1.3	-0.8	-1.3	-0.7
Sensitivity / hurt feelings	0.1	0.2	0.3	-0.3	0.5	0.6	-0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.4	-0.4	0.2	-0.4	-0.6
Vitamin and mineral supplements	0.1	0.1	0.3	0.5	0.1	-0.1	-0.4
Diabetes (mother)	0.1	0.1	0.2	-0.2	-0.4	0.3	-0.5
Leg fat-free mass (left)	0.1	0.3	0.8	0.1	-0.5	-0.9	-0.1
Taking other prescription medications	0.1	0.2	0.4	0.6	-0.2	-0.2	0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	0.2	0.5	0.1	-0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	0.4	0.2	-0.7	0.0
Leg predicted mass (left)	0.1	0.3	0.8	0.2	-0.5	-0.9	-0.2
Trunk fat mass	0.1	0.3	0.3	0.6	-0.5	-0.6	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.3	0.2	0.5	0.7
Allergy	0.1	0.1	0.3	0.3	-0.1	-0.4	0.6
Medication: Simvastatin	0.1	0.1	0.4	0.4	-0.1	-0.6	0.1
Neuroticism score	0.1	0.3	0.9	-0.4	-0.9	0.3	-0.1
Weight	0.1	0.5	1.2	0.0	-0.7	-1.1	-0.7
Hip circumference	0.1	0.4	0.6	0.0	-0.5	-0.8	-0.7
Alcohol intake versus 10 years previously	0.1	0.2	0.3	0.5	0.2	0.5	0.5
Falls in the last year	0.1	0.1	0.1	0.3	-0.3	0.3	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.0	0.6	0.1	0.7	1.0
Pulse rate	0.1	0.1	0.2	0.3	-0.5	0.0	-0.4
Asthma	0.1	0.1	0.2	-0.1	-0.1	0.5	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	0.1	-0.5	0.3	0.3
Lung cancer (father)	0.1	0.1	0.3	0.5	0.1	-0.0	0.3
Pulse wave Arterial Stiffness index	0.1	0.2	0.3	0.1	0.5	0.2	-0.5
Arm fat mass (right)	0.1	0.2	0.3	0.4	-0.4	-0.6	-0.5
Hair/balding pattern: Pattern 4	0.1	0.2	0.5	0.3	0.2	-0.5	-0.7
Birth weight of first child	0.1	0.2	0.3	0.4	-0.5	-0.2	0.5
Peak expiratory flow (PEF)	0.1	0.2	0.7	0.1	-0.2	-0.8	-0.3
Body fat percentage	0.1	0.3	0.4	0.2	-0.6	-0.7	-0.7
Arm fat-free mass (right)	0.1	0.5	1.5	-0.0	-0.1	-1.2	-0.6
Comparative body size at age 10	0.1	0.3	0.9	0.4	-0.2	-0.9	-0.3
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.5	-0.4	-0.2	0.4
Whole body fat mass	0.1	0.4	0.7	0.2	-0.6	-0.9	-0.7
Arm predicted mass (right)	0.1	0.4	1.3	-0.0	-0.1	-1.1	-0.6
Pulse rate, automated reading	0.1	0.3	0.8	0.6	-0.4	0.9	-0.1
Alcohol intake frequency.	0.1	0.3	0.8	-0.9	-0.2	-0.2	-0.3
Overall health rating	0.1	0.1	0.2	0.2	-0.4	-0.5	0.2
Arm fat percentage (left)	0.1	0.3	0.9	-0.0	-0.9	-0.5	-0.3
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.5	0.1	0.2	-0.3
Number of self-reported non-cancer illnesses	0.1	0.1	0.2	0.1	0.2	-0.4	0.5
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.0	-0.2	0.4	0.5
Arm fat-free mass (left)	0.1	0.5	1.5	0.1	0.1	-1.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	0.3	0.5	-0.4	-0.3
Alcohol drinker status: Previous	0.1	0.1	0.2	0.2	0.2	-0.4	-0.2
Bipolar Disorder (2018)	0.0	0.0	0.1	0.2	0.3	0.2	0.0
Blood Eosinophil Count	0.0	0.4	0.9	0.2	-0.7	-0.1	1.0
Trunk fat percentage	0.0	0.2	0.3	0.6	-0.5	-0.3	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.1	0.3	-0.2	0.2	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	-0.1	0.3	0.4	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.1	0.1	-0.2	-0.1	-0.3
Arm fat percentage (right)	0.0	0.2	0.3	0.1	-0.6	-0.5	-0.3
Trunk fat-free mass	0.0	0.2	0.7	0.2	0.0	-0.8	-0.1
Trunk predicted mass	0.0	0.2	0.7	0.2	0.1	-0.8	-0.1
Whole body fat-free mass	0.0	0.2	0.8	0.1	-0.2	-0.9	-0.2
Leg fat-free mass (right)	0.0	0.2	0.4	0.1	-0.6	-0.7	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.0	0.1	-0.1	0.2	0.1
Asthma (self-reported)	0.0	0.0	0.1	-0.2	-0.2	0.2	0.2
Whole body water mass	0.0	0.2	0.9	0.1	-0.2	-0.9	-0.2
Leg predicted mass (right)	0.0	0.2	0.5	0.1	-0.6	-0.7	-0.0
Basal metabolic rate	0.0	0.2	0.6	0.3	-0.2	-0.8	-0.2

Hub : Genes

C14orf169

Models

Trait associations