TWAS hub - C14orf53

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Colon Adenocarcinoma	0.091	0.073	0.00026	0.074	0.069	0.082	NA	0.089	4.5e-05	0.00008	1.7e-05	NA	8.3e-06
2	TCGA	Rectum Adenocarcinoma	0.118	0.084	0.00750	0.019	0.059	-0.002	NA	0.017	1.1e-01	0.01700	3.6e-01	NA	1.3e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Laxatives (e.g. Dulcolax, Senokot)	8.1	9.6	10.4	-3.2	-3.0
Risk taking	7.8	11.4	11.5	3.4	3.4
Average weekly champagne plus white wine intake	5.8	7.9	10.7	2.3	3.3
Major Depression (MDD)	5.5	6.7	8.4	-2.9	-2.2
Qualifications: College or University degree	5.5	17.4	25.5	3.0	5.1
Age started oral contraceptive pill	5.0	6.2	6.4	2.5	2.5
Supplements: Calcium	5.0	5.5	5.9	-2.2	-2.4
Qualifications: nursing, teaching	4.9	7.6	12.0	1.8	3.5
Diabetes (self-reported)	4.8	7.4	7.7	2.7	2.8
Impedance of leg (right)	4.7	23.0	31.3	-3.8	-5.6
Qualifications: None of the above	4.5	9.6	14.2	-2.2	-3.8
Qualifications: CSEs or equivalent	4.3	5.6	6.2	-2.5	-2.2
Age at first live birth	4.3	7.7	9.3	2.5	3.1
Fed-up feelings	4.2	7.7	9.2	-3.0	-2.5
Health satisfaction	4.2	5.5	7.5	-1.9	-2.7
Ever had prostate specific antigen (PSA) test	4.2	4.9	6.5	2.6	1.8
Qualifications: A levels/AS levels or equivalent	4.1	9.1	12.5	2.4	3.5
Diabetes diagnosed by doctor	3.9	6.4	7.7	2.3	2.8
Worry too long after embarrassment	3.6	6.0	6.3	2.4	2.5
Friendships satisfaction	3.6	4.4	5.1	-1.9	-2.3
Multivitamins +/- minerals	3.4	4.3	5.7	-1.7	-2.4
Loneliness, isolation	3.4	4.7	7.2	-2.7	-1.5
Vitamin and mineral supplements	3.3	4.4	4.8	2.0	2.2
Type 2 Diabetes (T2D) (2018)	3.2	5.9	7.2	2.2	2.7
Impedance of leg (left)	3.2	15.7	22.0	-3.1	-4.7
Alcohol intake frequency.	3.2	7.4	8.4	-2.5	-2.9
Medication: Paracetamol	3.0	4.6	7.7	-1.2	-2.8
Hand grip strength (left)	2.9	7.6	9.5	3.1	2.4
Medication: Paracetamol	2.8	4.7	7.8	-1.3	-2.8
Supplements: Fish oil (including cod liver oil)	2.8	3.7	4.5	-1.7	-2.1
Bipolar Disorder (2018)	2.7	4.3	5.1	2.2	1.9
Depression (Nagel 2018)	2.6	3.9	6.6	-2.6	-1.1
Bipolar Disorder or Schizophrenia	2.5	6.0	8.1	2.0	2.8
Frequency of depressed mood in last 2 weeks	2.5	3.6	5.8	-2.4	-1.1
Hypothyroidism/myxoedema (self-reported)	2.5	4.8	5.2	2.1	2.3
Impedance of whole body	2.5	12.9	16.5	-3.0	-4.1
Medication: Levothyroxine sodium	2.4	4.1	4.5	2.1	1.9
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	3.6	-1.6	-1.9
Medication: Atorvastatin	2.4	3.0	3.2	1.8	1.7
Hypothyroidism (self reported)	2.3	5.2	6.3	2.0	2.5
Hearing difficulty/problems with background noise	2.3	3.7	5.6	2.4	1.4
Leg predicted mass (right)	2.3	12.1	15.2	3.0	3.9
Ever taken oral contraceptive pill	2.3	2.6	4.5	-0.8	-2.1
Basal cell carcinoma (self-reported)	2.3	2.7	3.8	1.3	1.9
Hair/balding pattern: Pattern 2	2.2	2.8	3.5	-1.4	-1.9
Financial difficulties in last 2 years	2.2	2.9	2.9	-1.7	-1.7
Leg fat-free mass (right)	2.2	12.0	15.0	3.0	3.9
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	3.6	1.3	1.9
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	3.9	-2.0	-0.9
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	3.3	1.8	1.8
Bipolar Disorder (2011)	1.9	1.8	1.8	1.3	1.3
Medication: Metformin	1.9	2.6	3.5	1.9	1.4
Headache pain in last month	1.9	3.4	4.9	-1.3	-2.2
Exposure to tobacco smoke outside home	1.9	2.5	3.1	-1.8	-1.4
Whole body water mass	1.9	10.6	12.1	3.0	3.5
Supplements: Zinc	1.8	1.9	2.0	-1.4	-1.4
Stomach or abdominal pain in last month	1.8	2.2	2.4	-1.6	-1.4
Trunk predicted mass	1.8	10.2	11.3	3.0	3.4
Breast cancer (self-reported)	1.8	2.2	2.5	-1.3	-1.6
Pack years adult smoking proportion	1.7	2.6	3.3	-1.4	-1.8
Whole body fat-free mass	1.7	9.6	11.2	2.8	3.3
Ever had bowel cancer screening	1.7	2.0	3.1	1.0	1.8
Mineral and other dietary supplements	1.7	2.3	2.5	1.6	1.5
Alcohol drinker status: Previous	1.7	1.9	2.1	-1.5	-1.3
Body Mass Index (BMI) (2010)	1.6	2.2	3.2	1.8	1.1
Hand grip strength (right)	1.6	4.2	5.6	2.4	1.7
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	1.9	-1.4	-1.2
Trunk fat-free mass	1.6	9.4	10.4	2.9	3.2
Noisy workplace	1.6	1.9	2.9	-1.0	-1.7
Mean time to correctly identify matches	1.6	3.0	5.3	2.3	0.8
Arm predicted mass (right)	1.6	8.2	9.4	2.7	3.1
Leg fat-free mass (left)	1.5	8.1	10.0	2.5	3.2
Leg predicted mass (left)	1.5	7.9	9.8	2.5	3.1
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	2.4	-1.2	-1.6
Impedance of arm (right)	1.5	6.9	8.9	-2.2	-3.0
Arm fat-free mass (right)	1.5	7.8	8.8	2.6	3.0
Basal metabolic rate	1.5	8.2	9.2	2.7	3.0
Pain experienced in last month	1.5	2.5	4.4	0.8	2.1
Maternal smoking around birth	1.4	2.0	2.2	-1.4	-1.5
Neck or shoulder pain in last month	1.4	2.0	3.6	-0.7	-1.9
Arm fat-free mass (left)	1.4	7.0	7.9	2.5	2.8
Arm predicted mass (left)	1.4	7.2	8.3	2.5	2.9
Schizophrenia (2018)	1.3	2.6	4.7	0.7	2.2
Reaction Time	1.3	2.5	4.4	2.1	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	3.3	-1.8	-0.1
Hayfever, allergic rhinitis or eczema	1.3	2.8	2.9	-1.6	-1.7
Hair/balding pattern: Pattern 3	1.3	1.9	2.1	1.5	1.3
Number of full brothers	1.3	1.6	3.1	-0.4	-1.8
Average weekly spirits intake	1.2	1.5	1.9	1.4	1.0
Falls in the last year	1.2	1.7	1.9	1.2	1.4
Impedance of arm (left)	1.2	5.7	7.7	-1.9	-2.8
Medication: Ibuprofen	1.2	1.4	2.1	-0.8	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	1.6	-1.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	2.5	-0.6	-1.6
Knee pain experienced in last month	1.2	1.8	3.6	0.1	-1.9
Schizophrenia (2014)	1.1	2.5	3.5	1.2	1.9
Angina	1.1	1.4	1.9	-1.0	-1.4
Townsend deprivation index at recruitment	1.1	1.5	1.5	-1.2	-1.2
Alcohol usually taken with meals	1.1	1.8	2.3	1.1	1.5
Medication: Simvastatin	1.1	1.7	2.4	-1.6	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.0	-0.9	-1.4
Mouth/teeth dental problems: Loose teeth	1.1	1.3	1.5	-1.2	-1.1
Angina (self-reported)	1.1	1.4	1.7	-1.1	-1.3
Pack years of smoking	1.1	1.7	2.4	-1.0	-1.5
Fasting Glucose	1.0	1.2	1.6	-1.3	-0.9
Fluid intelligence score	1.0	2.1	2.6	1.3	1.6
Breastfed as a baby	1.0	1.2	2.0	-1.4	-0.7
Number of children fathered	1.0	1.2	2.3	1.5	0.1
Age at last live birth	1.0	1.5	2.4	0.8	1.6
Commuting to job workplace: Public transport	1.0	1.2	2.4	-1.6	-0.0
Ever smoked	1.0	1.8	2.0	1.4	1.3
Unable to work because of sickness or disability	1.0	1.2	1.5	-1.0	-1.2
Schizophrenia vs Biploar Disorder	0.9	1.2	2.0	-1.4	-0.7
Crohns Disease (2017)	0.9	2.0	2.3	-1.3	-1.5
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.1	1.4	0.4
Chronic bronchitis/emphysema (father)	0.9	1.0	1.1	-1.1	-1.0
Had menopause	0.9	1.1	1.4	1.2	0.9
Mouth/teeth dental problems	0.9	1.3	2.2	0.7	1.5
Pulse wave Arterial Stiffness index	0.9	1.1	1.5	-0.8	-1.2
Pulse wave peak to peak time	0.9	1.1	1.5	0.8	1.2
Emphysema/chronic bronchitis	0.9	1.0	1.8	-1.3	-0.5
Medication for pain relief, constipation, heartburn	0.9	1.6	2.8	0.6	1.7
Depressed Affect (Nagel 2018)	0.8	1.6	2.6	-1.6	-0.8
Triglycerides	0.8	1.2	2.4	-1.5	-0.3
Relative age voice broke	0.8	1.3	2.6	1.6	0.1
Pulse wave reflection index	0.8	1.0	1.5	-0.7	-1.2
Birth weight	0.8	1.7	2.6	0.8	1.6
Medication: Omeprazole	0.8	1.0	1.8	1.4	0.3
Number of full sisters	0.8	1.0	1.8	-0.5	-1.4
Osteoporosis (self-reported)	0.8	1.0	1.3	0.9	1.1
Irritable Bowel Disease (IBD)	0.7	1.7	1.7	-1.3	-1.3
Lupus	0.7	1.1	1.7	1.3	0.7
Blood White Count	0.7	5.3	7.4	-2.7	-1.8
Lung cancer (father)	0.7	0.9	1.1	-1.1	-0.8
Suffer from ‘nerves’	0.7	1.1	1.3	0.9	1.2
Overall health rating	0.7	1.6	2.6	-0.7	-1.6
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.5	1.2	0.4
Illnesses of siblings: Diabetes	0.7	0.8	1.1	0.7	1.0
Medication for cholesterol	0.7	1.1	1.4	-1.2	-0.8
Back pain experienced in last month	0.7	1.1	1.7	-0.6	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.5	1.2	0.4
Mean Putamen Volume	0.6	0.6	0.8	-0.9	-0.7
HbA1C	0.6	0.7	0.9	1.0	0.7
Ulcerative Colitis	0.6	0.9	1.3	-1.1	-0.8
Allergy or Eczema	0.6	1.6	1.8	-1.2	-1.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	0.9	0.9	0.6
Medication for hormone replacement therapy	0.6	0.7	1.4	1.2	0.1
Medication: Co-codamol	0.6	0.6	0.9	-0.6	-0.9
Severe depression (siblings)	0.6	0.7	1.0	-0.7	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	0.8	-0.9	-0.8
Alcohol intake versus 10 years previously	0.6	0.9	1.0	0.9	1.0
Standing height	0.6	5.5	5.7	2.3	2.4
Length of working week for main job	0.6	0.7	1.4	0.2	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.6	-1.3	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.1	-1.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.5	1.2	1.3	1.1	1.1
HDL Cholesterol	0.5	0.8	1.7	1.3	0.1
Height	0.5	9.1	11.9	3.5	2.5
Waist Hip Ratio (WHR)	0.5	2.3	2.8	-1.4	-1.7
Cardiovascular Disease	0.5	1.7	3.2	-1.8	-0.4
Sensitivity / hurt feelings	0.5	0.8	0.8	0.9	0.9
Diabetes (mother)	0.5	0.6	1.2	-1.1	0.0
Heart attack	0.5	0.6	0.8	0.9	0.7
Medication: Ramipril	0.5	0.6	0.8	0.6	0.9
Weight	0.5	2.4	2.6	1.6	1.5
Illnesses of mother	0.5	0.6	1.1	1.0	0.4
Loud music exposure frequency	0.5	0.6	0.6	0.8	0.7
Hypertension (Self-reported)	0.5	1.5	2.8	-1.7	-0.4
Hearing aid user	0.5	0.6	1.2	0.0	-1.1
Irritability	0.5	0.8	1.1	-0.7	-1.0
Fractured/broken bones in last 5 years	0.5	0.6	0.7	0.8	0.9
Heart disease (siblings)	0.5	0.6	0.9	0.5	0.9
Prostate Cancer	0.4	0.6	0.8	-0.9	-0.7
Coronary Artery Disease (CAD)	0.4	0.5	0.7	-0.9	-0.5
Crohns Disease (2012)	0.4	0.7	1.2	-1.1	-0.4
BMI	0.4	2.3	2.3	1.5	1.5
Neuroticism	0.4	1.0	1.7	0.6	1.3
Chronotype (morning person)	0.4	0.9	1.6	-0.4	-1.3
Current tobacco smoking	0.4	0.6	1.2	-1.1	-0.1
Age when periods started (menarche)	0.4	1.0	1.7	-0.6	-1.3
Serious illness, injury or assault to yourself	0.4	0.5	0.9	-0.9	-0.4
Sitting height	0.4	2.8	4.0	1.3	2.0
Number of incorrect matches in round	0.4	0.6	0.8	0.7	0.9
Mouth/teeth dental problems: Dentures	0.4	0.6	1.3	-0.2	-1.1
Exposure to tobacco smoke at home	0.4	0.5	0.7	-0.8	-0.5
Leg fat percentage (right)	0.4	1.5	2.6	-0.6	-1.6
Medication: Blood pressure	0.4	0.7	1.1	0.5	1.1
Pulse rate, automated reading	0.4	1.2	2.1	-1.4	-0.6
Comparative height size at age 10	0.4	2.2	3.7	0.8	1.9
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.6	0.8	0.6
Osteoarthritis (self-reported)	0.4	0.5	1.0	1.0	-0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	0.9	-0.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.4	1.2	-0.5
Commuting to job workplace: Cycle	0.4	0.5	0.6	0.5	0.8
Ulcerative Colitis (UC)	0.3	0.6	0.6	-0.8	-0.8
Breast Cancer	0.3	0.7	1.2	-0.5	-1.1
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.6	-0.3	-0.8
Blood Platelet Count	0.3	3.3	4.4	1.5	2.1
Hearing difficulty/problems: Yes	0.3	0.5	1.0	1.0	-0.1
Relative age of first facial hair	0.3	0.7	1.2	1.1	0.5
Ever had hysterectomy (womb removed)	0.3	0.4	0.7	0.2	-0.8
Average weekly fortified wine intake	0.3	0.3	0.6	-0.3	0.8
Taking other prescription medications	0.3	0.4	0.7	0.9	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	0.1	0.8
Past tobacco smoking	0.3	0.6	1.2	-1.1	-0.1
Father’s age at death	0.3	0.4	0.6	0.4	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.5	0.7	0.6
Peak expiratory flow (PEF)	0.3	0.7	1.0	1.0	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.6	0.4	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.4	-0.6	-0.6
Shortness of breath walking on level ground	0.3	0.3	0.5	-0.4	-0.7
Average weekly red wine intake	0.3	0.4	0.6	0.8	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.6	1.1	0.2	-1.0
Medication: Gliclazide	0.3	0.4	0.6	0.4	0.7
Arm fat mass (left)	0.3	1.2	1.8	1.3	0.8
Mother’s age at death	0.3	0.3	0.5	-0.7	0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.7	-0.4	-0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.3	0.6	0.2
LDL Cholesterol	0.2	0.3	0.6	-0.8	-0.1
Rheumatoid Arthritis	0.2	0.3	0.5	-0.7	-0.2
Blood Eosinophil Count	0.2	1.3	2.0	-1.4	-0.7
Tanning	0.2	2.0	2.0	-1.4	-1.4
Medication: Atenolol	0.2	0.2	0.4	-0.6	-0.2
High blood pressure (mother)	0.2	0.3	0.5	-0.7	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.4	-0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.7	0.8	0.6
Allergy	0.2	0.4	0.5	0.5	0.7
Hip circumference	0.2	0.9	1.3	1.1	0.7
Worrier / anxious feelings	0.2	0.4	0.5	0.7	0.6
Pulse rate	0.2	0.3	0.7	-0.8	0.1
Arm fat mass (right)	0.2	1.0	1.5	1.2	0.7
Hair/balding pattern: Pattern 4	0.2	0.4	0.7	0.9	0.0
Birth weight of first child	0.2	0.4	0.5	0.5	0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.2	0.4	0.5
Body fat percentage	0.2	0.7	1.5	-0.2	-1.2
Comparative body size at age 10	0.2	0.6	1.1	-1.0	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	-0.6	0.0
Family relationship satisfaction	0.2	0.2	0.4	-0.1	0.7
Leg pain on walking	0.2	0.3	0.4	-0.7	-0.3
Medication: Aspirin	0.2	0.3	0.4	0.4	0.7
Smoking status: Previous	0.2	0.3	0.5	0.7	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.5	0.2	0.7
Commuting to job workplace: Walk	0.2	0.2	0.3	-0.4	-0.5
Medication: Aspirin	0.2	0.2	0.4	0.3	0.6
High cholesterol (Self-reported)	0.2	0.4	0.8	-0.9	-0.0
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.7	-0.2
Illnesses of father: High blood pressure	0.2	0.2	0.4	0.2	0.7
Leg fat percentage (left)	0.2	0.7	1.3	-0.3	-1.2
Average weekly beer plus cider intake	0.2	0.3	0.3	-0.6	-0.5
Myopia	0.2	0.3	0.5	-0.7	-0.3
Cholesterol lowering medication	0.2	0.3	0.3	0.6	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.3	0.6	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.1	0.6
Neuroticism (Nagel 2018)	0.1	0.2	0.4	-0.6	-0.2
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.3	0.4
Alzheimer’s Disease (including proxy)	0.1	0.2	0.4	0.1	0.6
Ovarian Cancer	0.1	0.1	0.1	0.1	0.4
Age at First Birth	0.1	0.1	0.1	0.3	0.4
Blood Red Count	0.1	1.4	2.5	1.6	0.5
Systolic Blood Pressure	0.1	0.4	0.8	-0.9	-0.2
Smoking Status	0.1	0.2	0.3	0.4	0.5
Number of treatments/medications taken	0.1	0.2	0.3	0.6	-0.2
Trunk fat percentage	0.1	0.5	1.0	0.1	-1.0
High blood pressure	0.1	0.4	0.7	-0.9	0.1
Body mass index (BMI)	0.1	0.4	0.5	0.7	0.5
Trunk fat mass	0.1	0.5	1.0	1.0	0.2
Had other major operations	0.1	0.1	0.2	-0.3	0.4
Pain all over the body in last month	0.1	0.1	0.1	-0.0	0.4
Illnesses of siblings	0.1	0.2	0.3	-0.3	-0.6
Neuroticism score	0.1	0.1	0.2	0.2	0.5
Time employed in main current job	0.1	0.1	0.1	0.4	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.1	-0.2	0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.2	0.5	0.3
Depression (self-reported)	0.1	0.1	0.2	0.0	0.4
Medication: Lansoprazole	0.1	0.1	0.3	0.5	0.1
Prospective memory result	0.1	0.1	0.2	0.0	-0.4
Medication: Amlodipine	0.1	0.1	0.1	0.3	0.3
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.3	-0.6	-0.1
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.2	0.5
Migraine (self-reported)	0.1	0.1	0.2	0.4	-0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.4	0.2
Heart disease (mother)	0.1	0.2	0.3	-0.5	-0.3
Whole body fat mass	0.1	0.3	0.6	0.8	0.2
Chest pain or discomfort	0.1	0.2	0.3	-0.5	0.3
Had major operations	0.1	0.1	0.2	0.1	0.4
Supplements: Vitamin C	0.1	0.2	0.3	-0.6	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.3	-0.5	-0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.4	-0.2
Smoking status: Current	0.1	0.2	0.4	-0.6	0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.4	0.6
Miserableness	0.1	0.2	0.5	-0.7	-0.0
Guilty feelings	0.1	0.1	0.2	0.4	-0.0
Financial situation satisfaction	0.1	0.2	0.3	0.6	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.5	-0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.2	0.4
Medication: Blood pressure	0.1	0.3	0.4	-0.6	-0.3
Ever depressed for a whole week	0.1	0.1	0.2	-0.2	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.3	0.2	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.3	-0.1	-0.6
Worry (Nagel 2018)	0.0	0.1	0.1	-0.3	0.2
Neuroticism (2016)	0.0	0.0	0.1	-0.3	0.1
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.2	0.0
Heel T-Score	0.0	0.4	0.7	0.2	0.9
Respiratory disease	0.0	0.1	0.1	-0.2	-0.3
Lung FEV1/FVC ratio	0.0	0.1	0.2	0.4	0.3
Lung FVC	0.0	0.2	0.3	-0.0	-0.5
Hair Pigment	0.0	1.2	1.8	1.3	0.7
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.4	-0.1
Diabetes (father)	0.0	0.0	0.0	0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	0.4	-0.1
Supplements: Glucosamine	0.0	0.0	0.0	-0.1	-0.2
Waist circumference	0.0	0.1	0.2	0.5	0.2
Nervous feelings	0.0	0.0	0.0	-0.2	0.0
Forced vital capacity (FVC)	0.0	0.0	0.0	0.2	-0.0
Arm fat percentage (right)	0.0	0.1	0.2	0.4	-0.3
Number of live births	0.0	0.0	0.0	0.2	-0.2
Happiness	0.0	0.0	0.1	-0.3	0.0
Asthma	0.0	0.1	0.1	0.4	-0.1
Medication: Cholesterol lowering	0.0	0.1	0.1	-0.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.1	-0.0	-0.3
Tense / ‘highly strung’	0.0	0.1	0.1	-0.2	0.3
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.1	-0.2
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	0.4	-0.2
Glaucoma (self-reported)	0.0	0.0	0.0	-0.2	0.1
Gout (self-reported)	0.0	0.0	0.0	-0.1	-0.0
High blood pressure (siblings)	0.0	0.0	0.1	0.1	0.3
Forced vital capacity (FVC), Best measure	0.0	0.0	0.1	-0.1	-0.2
Wheeze or whistling in the chest in last year	0.0	0.0	0.0	-0.0	-0.1
Medication: Allopurinol	0.0	0.0	0.0	-0.1	-0.1
Leg fat mass (right)	0.0	0.1	0.1	0.3	-0.3
Illnesses of father: Heart disease	0.0	0.0	0.1	-0.2	-0.2
Arm fat percentage (left)	0.0	0.2	0.3	0.6	-0.2
Mood swings	0.0	0.1	0.1	0.3	0.1
Eye problems/disorders: Cataract	0.0	0.0	0.1	-0.0	-0.2
Asthma (self-reported)	0.0	0.0	0.0	0.1	-0.1
Wears glasses or contact lenses	0.0	0.0	0.1	0.1	0.3
Medication: Lisinopril	0.0	0.1	0.1	0.2	0.2
Alcohol drinker status: Never	0.0	0.0	0.1	-0.2	0.1
Number of operations (self-reported)	0.0	0.0	0.1	0.2	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.1	-0.1	0.4
Leg fat mass (left)	0.0	0.1	0.3	0.5	0.0

Hub : Genes

C14orf53

Models

Trait associations