TWAS hub - C16orf59

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0309	0.0150	0.014	0.041	0.011	0.023	0.015	0.036	4.3e-06	0.0110	0.00058	0.004	1.6e-05
2	TCGA	Breast Invasive Carcinoma	0.0165	0.0141	0.001	0.004	0.012	0.007	NA	0.009	3.9e-02	0.0011	0.00980	NA	4.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Height	5.4	104.8	130.0	8.9	-11.4
Comparative height size at age 10	5.4	29.6	38.2	4.6	-6.2
Standing height	5.1	50.8	69.6	5.7	-8.3
Illnesses of father: High blood pressure	5.1	6.3	6.8	2.6	-2.4
Prospective memory result	4.4	5.4	8.2	1.6	-2.9
Exposure to tobacco smoke outside home	4.4	5.8	5.9	-2.4	2.4
Forced expiratory volume in 1-second (FEV1), predicted	3.8	7.8	9.1	2.6	-3.0
Knee pain experienced in last month	3.5	5.5	8.5	-1.6	2.9
Migraine (self-reported)	3.3	4.1	4.4	1.9	-2.1
Heart disease (mother)	3.1	3.8	4.5	2.1	-1.7
Heel T-Score	3.0	24.2	31.2	-4.2	5.6
Mouth/teeth dental problems: Loose teeth	2.9	3.5	5.1	2.2	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.6	11.9	2.3	-3.5
Arm fat-free mass (right)	2.7	13.8	19.4	2.9	-4.4
Wheeze or whistling in the chest in last year	2.7	4.9	6.2	-1.9	2.5
Type 2 Diabetes (T2D) (2018)	2.6	4.9	5.6	-2.1	2.4
Hair/balding pattern: Pattern 2	2.5	3.2	3.9	-1.6	2.0
Forced vital capacity (FVC)	2.5	9.8	16.1	1.8	-4.0
Depression (self-reported)	2.5	3.0	3.3	1.6	-1.8
Trunk predicted mass	2.5	14.2	20.7	2.8	-4.5
Trunk fat-free mass	2.4	13.8	19.9	2.8	-4.5
Medication: Seretide 50 evohaler	2.4	2.7	5.0	-0.7	2.2
Mean time to correctly identify matches	2.4	4.5	5.0	2.2	-2.0
Arm predicted mass (right)	2.4	12.2	17.5	2.6	-4.2
Alcohol drinker status: Never	2.4	2.8	2.9	-1.7	1.7
Arm fat-free mass (left)	2.4	12.1	16.8	2.7	-4.1
Arm predicted mass (left)	2.4	12.2	16.6	2.8	-4.1
Crohns Disease (2017)	2.3	5.1	8.5	1.3	-2.9
Medication: Atenolol	2.3	2.9	4.0	2.0	-1.3
Sitting height	2.3	16.5	24.2	3.0	-4.9
Birth weight	2.3	5.0	6.8	1.8	-2.6
Breast Cancer	2.2	5.2	5.5	2.2	-2.3
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	3.2	-1.8	1.4
Forced expiratory volume in 1-second (FEV1)	2.2	7.5	11.1	2.0	-3.3
Forced vital capacity (FVC), Best measure	2.2	8.1	12.5	1.9	-3.5
Whole body water mass	2.2	12.6	17.6	2.8	-4.2
Pain all over the body in last month	2.1	2.3	3.7	-1.9	0.9
Asthma	2.1	4.2	7.7	-0.8	2.8
Whole body fat-free mass	2.1	12.1	17.1	2.7	-4.1
Asthma (self-reported)	2.1	4.2	7.6	-0.9	2.8
Crohns Disease (2012)	2.0	3.2	6.5	0.0	-2.5
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.2	3.8	-1.9	1.6
Systolic Blood Pressure	1.9	9.3	12.0	2.6	-3.5
Ever unenthusiastic/disinterested for a whole week	1.9	2.4	4.5	0.5	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	3.5	-0.9	1.9
Basal metabolic rate	1.9	10.8	14.3	2.7	-3.8
Diastolic blood pressure, automated reading	1.9	5.8	7.7	2.8	-2.0
Hearing difficulty/problems: Yes	1.8	2.8	3.0	1.6	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	4.4	1.1	-2.1
Ulcerative Colitis (UC)	1.7	3.1	4.2	-2.0	1.5
Loud music exposure frequency	1.7	1.8	1.9	1.3	-1.4
Reaction Time	1.6	3.1	3.4	1.8	-1.7
HbA1C	1.6	1.8	2.1	-1.2	1.4
Systolic blood pressure, automated reading	1.6	4.7	5.0	2.1	-2.2
Leg fat-free mass (left)	1.6	8.5	11.0	2.4	-3.3
Birth weight of first child	1.6	3.0	4.7	1.1	-2.2
Shortness of breath walking on level ground	1.6	1.9	3.2	-1.8	0.7
Sensitivity / hurt feelings	1.5	2.5	3.3	1.3	-1.8
Leg predicted mass (left)	1.5	8.1	10.8	2.4	-3.3
Chronic bronchitis/emphysema (mother)	1.5	1.7	1.8	-1.3	1.3
Suffer from ‘nerves’	1.5	2.3	2.7	-1.6	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.9	2.2	-1.5	1.2
Chronic bronchitis/emphysema (father)	1.4	1.6	2.2	-1.5	1.0
Weight	1.4	6.8	7.2	2.7	-2.5
Leg fat-free mass (right)	1.4	7.3	9.9	2.2	-3.1
Guilty feelings	1.4	2.1	3.0	1.1	-1.7
Ever depressed for a whole week	1.4	1.8	2.1	1.2	-1.5
Commuting to job workplace: Car/motor vehicle	1.3	1.5	2.3	-0.9	1.5
Leg predicted mass (right)	1.3	6.9	9.4	2.1	-3.1
Smoking Status	1.2	3.0	4.4	1.3	-2.1
Hypothyroidism (self reported)	1.2	2.7	4.7	2.2	-0.8
Had other major operations	1.2	1.5	2.8	1.7	-0.3
Hair/balding pattern: Pattern 3	1.2	1.8	2.5	1.0	-1.6
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.9	-0.5	1.7
Medication for pain relief, constipation, heartburn	1.2	2.1	2.1	1.4	-1.4
Family relationship satisfaction	1.2	1.5	1.9	1.0	-1.4
Age at First Birth	1.1	1.7	2.4	-1.5	1.0
Age when periods started (menarche)	1.1	2.6	4.7	-2.2	0.8
Lung cancer (father)	1.1	1.3	1.5	-1.2	1.0
Pulse wave reflection index	1.1	1.4	1.7	1.3	-1.0
Smoking status: Previous	1.1	1.6	3.0	0.5	-1.7
Age started oral contraceptive pill	1.1	1.4	1.9	0.9	-1.4
Myopia	1.1	1.6	2.8	-1.7	0.7
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	1.6	-1.3	1.1
Ever had hysterectomy (womb removed)	1.0	1.1	1.1	1.1	-1.0
Medication: Co-codamol	1.0	1.2	1.5	-1.0	1.2
Waist circumference	1.0	3.7	6.0	2.5	-1.1
Medication: Simvastatin	1.0	1.5	2.3	1.5	-0.9
Time employed in main current job	1.0	1.1	1.5	0.8	-1.2
Number of children fathered	1.0	1.1	2.1	-0.3	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.6	-1.3	0.9
Osteoarthritis (self-reported)	1.0	1.4	1.6	-1.1	1.3
Medication: Blood pressure	1.0	1.9	3.8	1.9	0.2
Alcohol usually taken with meals	0.9	1.5	1.7	1.1	-1.3
Had menopause	0.9	1.2	1.2	1.1	-1.1
Allergy	0.9	2.2	3.8	0.7	-1.9
Hip circumference	0.9	3.8	5.1	2.3	-1.6
Illnesses of siblings: Diabetes	0.9	1.1	1.4	1.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	2.6	1.0	-1.6
Basal cell carcinoma (self-reported)	0.9	1.0	2.0	-0.1	-1.4
Lupus	0.8	1.2	2.2	0.4	-1.5
Schizophrenia (2014)	0.8	1.8	3.7	0.0	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.4	-1.2	0.9
Medication: Levothyroxine sodium	0.8	1.4	2.2	1.5	-0.8
Trunk fat mass	0.8	3.6	5.6	2.4	-1.3
Number of incorrect matches in round	0.8	1.3	2.6	0.1	-1.6
Pulse rate	0.8	1.3	2.1	-0.8	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.8	0.3	-1.3
Medication: Lansoprazole	0.8	1.0	1.4	-0.7	1.2
Medication: Paracetamol	0.8	1.3	1.8	1.4	-0.9
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	2.9	1.7	-0.6
Number of full brothers	0.8	1.1	1.4	-0.9	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.3	-1.2	0.7
Medication: Allopurinol	0.8	1.1	1.2	-1.1	1.0
Medication: Omeprazole	0.8	1.0	1.4	-1.2	0.8
Chest pain or discomfort	0.8	1.1	2.3	0.0	1.5
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.0	-1.0	1.0
Blood White Count	0.7	5.2	5.9	2.1	-2.4
Respiratory disease	0.7	1.7	3.2	-0.2	1.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	1.4	-0.1	1.2
Diabetes (father)	0.7	0.8	0.9	1.0	-0.9
Fed-up feelings	0.7	1.3	2.3	-1.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	0.9	0.9	-0.9
Number of live births	0.7	1.1	1.2	-1.0	1.1
Noisy workplace	0.7	0.9	1.6	0.4	-1.3
Diabetes diagnosed by doctor	0.7	1.1	1.4	-0.9	1.2
Illnesses of father: None of the above (group 1)	0.7	0.8	1.1	-0.8	1.0
Ever taken oral contraceptive pill	0.7	0.7	1.0	-1.0	0.7
Schizophrenia (2018)	0.6	1.2	2.5	0.0	-1.6
Alzheimer’s Disease (in mother)	0.6	0.7	0.7	0.8	-0.8
Major Depression (MDD)	0.6	0.7	1.4	0.0	-1.2
Ovarian Cancer	0.6	0.8	1.5	-0.2	1.2
Comparative body size at age 10	0.6	1.6	2.7	0.7	-1.6
Age at first live birth	0.6	1.1	1.2	-1.1	1.0
Medication: Aspirin	0.6	0.7	1.0	-1.0	0.7
Average weekly red wine intake	0.6	0.8	1.1	0.8	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.2	1.1	-0.4
Medication: Atorvastatin	0.6	0.8	1.0	-1.0	0.8
Number of operations (self-reported)	0.6	0.9	1.8	-0.3	1.3
Irritability	0.6	1.0	1.9	-1.4	0.3
Supplements: Calcium	0.6	0.6	1.0	-0.5	1.0
Heart disease (siblings)	0.6	0.7	1.0	1.0	-0.6
Worry (Nagel 2018)	0.5	1.0	1.8	-1.4	0.3
Medication: Metformin	0.5	0.7	1.1	-0.6	1.1
Multivitamins +/- minerals	0.5	0.6	1.1	-1.0	0.3
Hearing difficulty/problems with background noise	0.5	0.8	1.3	0.6	-1.1
Worrier / anxious feelings	0.5	0.9	1.7	0.2	-1.3
Hair/balding pattern: Pattern 4	0.5	1.2	2.4	1.5	-0.1
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	0.7	-0.8	0.8
Whole body fat mass	0.5	2.1	3.6	1.9	-0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.8	0.9	-0.6
Medication: Paracetamol	0.5	0.8	1.7	1.3	-0.0
Ever smoked	0.5	0.9	1.7	0.3	-1.3
Ever had prostate specific antigen (PSA) test	0.5	0.5	0.9	-0.9	0.4
Commuting to job workplace: Cycle	0.5	0.6	1.0	1.0	-0.5
Fasting Glucose	0.4	0.5	0.9	-0.2	0.9
Pack years adult smoking proportion	0.4	0.5	1.1	-1.0	0.1
High blood pressure (mother)	0.4	0.6	1.2	1.1	-0.2
Past tobacco smoking	0.4	0.8	1.5	-0.1	1.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.0	-0.4	1.0
Medication: Ramipril	0.4	0.5	0.8	-0.5	0.9
Arm fat percentage (right)	0.4	1.5	3.0	0.3	1.7
Mouth/teeth dental problems: Dentures	0.4	0.7	0.8	-0.9	0.8
Tense / ‘highly strung’	0.4	0.6	1.2	-1.1	0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.1	-1.1	0.4
Glaucoma (self-reported)	0.4	0.5	0.9	0.3	-1.0
Pulse rate, automated reading	0.4	1.4	2.2	-0.8	1.5
Illnesses of father: Heart disease	0.4	0.5	1.0	1.0	0.0
Arm fat percentage (left)	0.4	1.6	3.1	0.3	1.8
Commuting to job workplace: Walk	0.4	0.5	0.9	0.2	-0.9
Average weekly champagne plus white wine intake	0.4	0.6	0.9	-0.4	1.0
Fractured/broken bones in last 5 years	0.4	0.5	0.7	0.9	-0.5
Unable to work because of sickness or disability	0.4	0.5	0.6	0.7	-0.6
Bipolar Disorder or Schizophrenia	0.3	0.6	1.3	0.0	-1.1
Alzheimer’s Disease (including proxy)	0.3	0.4	0.6	0.4	-0.8
Prostate Cancer	0.3	0.4	0.7	0.8	0.3
Mean Putamen Volume	0.3	0.4	0.8	0.0	-0.9
Primary Biliary Cirrhosis	0.3	0.4	0.8	0.0	-0.9
Rheumatoid Arthritis	0.3	0.4	0.8	0.0	0.9
Blood Platelet Count	0.3	3.8	4.9	-1.6	2.2
BMI	0.3	1.6	3.2	0.3	1.8
Waist Hip Ratio (WHR)	0.3	1.5	2.6	1.6	-0.7
Lung FEV1/FVC ratio	0.3	1.3	1.7	1.3	-1.0
Neuroticism	0.3	0.7	1.3	0.0	-1.1
Vitamin and mineral supplements	0.3	0.4	0.7	0.9	-0.2
Severe depression (siblings)	0.3	0.4	0.5	0.5	-0.7
Trunk fat percentage	0.3	1.3	2.7	1.6	-0.0
Financial difficulties in last 2 years	0.3	0.4	0.7	-0.9	-0.0
Diabetes (self-reported)	0.3	0.5	0.8	-0.4	0.9
Fluid intelligence score	0.3	0.6	1.2	-0.1	1.1
Falls in the last year	0.3	0.4	0.8	0.9	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.5	-0.7	0.4
Arm fat mass (right)	0.3	1.3	2.6	1.6	-0.2
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.7	-0.1	0.9
Qualifications: College or University degree	0.3	1.1	1.3	-1.1	0.9
Leg fat mass (right)	0.3	1.3	2.4	1.6	-0.5
Friendships satisfaction	0.3	0.4	0.7	-0.4	-0.8
Back pain experienced in last month	0.3	0.4	0.8	-0.3	0.9
Wears glasses or contact lenses	0.3	0.3	0.4	-0.5	-0.6
Hearing aid user	0.3	0.4	0.7	0.2	-0.8
Commuting to job workplace: Public transport	0.3	0.4	0.6	0.8	-0.4
Leg fat percentage (left)	0.3	1.0	1.7	0.4	1.3
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.4	-1.2	0.2
Leg fat mass (left)	0.3	1.3	2.3	1.5	-0.6
Depressed Affect (Nagel 2018)	0.2	0.4	0.7	0.4	-0.9
Depression (Nagel 2018)	0.2	0.3	0.7	-0.2	0.8
Schizophrenia vs Biploar Disorder	0.2	0.3	0.6	0.0	-0.7
Irritable Bowel Disease (IBD)	0.2	0.5	0.9	-1.0	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.9	0.9	0.4
Cardiovascular Disease	0.2	0.6	1.0	1.0	-0.4
Chronotype (morning person)	0.2	0.6	1.0	0.4	-1.0
Hand grip strength (left)	0.2	0.7	0.9	0.6	-0.9
Number of treatments/medications taken	0.2	0.3	0.6	0.8	0.2
Average weekly spirits intake	0.2	0.3	0.3	-0.5	0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.5	-0.7	0.3
Maternal smoking around birth	0.2	0.2	0.3	-0.4	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.4	-0.6	0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.2	-0.5	0.4
Qualifications: CSEs or equivalent	0.2	0.2	0.5	0.7	-0.0
High blood pressure	0.2	0.5	1.0	1.0	-0.1
Stomach or abdominal pain in last month	0.2	0.2	0.4	0.6	-0.1
Supplements: Glucosamine	0.2	0.3	0.5	0.7	-0.3
Body mass index (BMI)	0.2	0.8	1.6	0.1	1.3
Nervous feelings	0.2	0.4	0.7	-0.8	0.2
Heart attack	0.2	0.3	0.5	0.7	0.1
Illnesses of siblings	0.2	0.3	0.3	-0.6	0.5
Neuroticism score	0.2	0.3	0.6	-0.8	-0.1
Father’s age at death	0.2	0.3	0.5	0.7	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.5	-0.7	0.5
Happiness	0.2	0.3	0.6	0.1	-0.8
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	0.4	-0.5
Length of working week for main job	0.2	0.2	0.2	-0.5	0.5
Breastfed as a baby	0.2	0.2	0.3	0.6	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	-0.7	0.3
Headache pain in last month	0.2	0.4	0.5	0.7	0.4
Gout (self-reported)	0.2	0.2	0.3	-0.4	0.5
High blood pressure (siblings)	0.2	0.3	0.7	0.8	-0.0
Body fat percentage	0.2	0.8	1.0	1.0	0.8
Leg fat percentage (right)	0.2	0.9	1.1	0.8	1.1
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.6	0.3
Neck or shoulder pain in last month	0.2	0.3	0.5	0.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.3	-0.2	0.6
Had major operations	0.2	0.2	0.5	-0.1	0.7
Supplements: Vitamin C	0.2	0.2	0.2	-0.4	-0.5
Hypertension (Self-reported)	0.2	0.6	1.1	1.0	-0.4
Mood swings	0.2	0.3	0.4	-0.4	-0.7
Ever had bowel cancer screening	0.2	0.2	0.2	0.5	-0.4
Medication for cholesterol	0.2	0.3	0.6	-0.8	-0.2
Mineral and other dietary supplements	0.2	0.3	0.4	-0.5	0.6
Medication: Aspirin	0.2	0.3	0.4	-0.6	0.4
Arm fat mass (left)	0.2	0.9	1.9	1.4	-0.0
Number of self-reported non-cancer illnesses	0.2	0.3	0.7	-0.1	0.8
Mother’s age at death	0.2	0.2	0.4	-0.6	0.3
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	0.0	-0.7
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.6	-0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.6	0.1	-0.8
Medication: Lisinopril	0.2	0.3	0.5	0.7	-0.3
Pain experienced in last month	0.2	0.4	0.8	-0.1	-0.9
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.4	0.6	0.2
Pack years of smoking	0.2	0.3	0.7	-0.8	-0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.6	0.1	-0.8
Alzheimer’s Disease (in father)	0.1	0.1	0.1	-0.4	-0.2
Neuroticism (2016)	0.1	0.2	0.2	-0.5	0.4
Ulcerative Colitis	0.1	0.1	0.2	0.0	0.4
Blood Red Count	0.1	1.0	1.0	-1.0	1.0
Lung FVC	0.1	0.4	0.9	-0.9	-0.0
Tanning	0.1	1.8	2.7	-1.6	0.9
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.2	-0.1	-0.4
Relative age of first facial hair	0.1	0.1	0.2	-0.5	-0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.2	0.4	-0.4
Supplements: Zinc	0.1	0.1	0.1	-0.3	-0.2
Impedance of leg (right)	0.1	0.5	0.6	0.8	-0.6
Average weekly fortified wine intake	0.1	0.1	0.1	-0.3	0.4
Relative age voice broke	0.1	0.1	0.1	0.1	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.3	0.5	0.0
Qualifications: None of the above	0.1	0.3	0.6	0.0	-0.8
Mouth/teeth dental problems	0.1	0.2	0.4	0.1	-0.6
Impedance of arm (right)	0.1	0.3	0.6	0.8	0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.3	0.0	-0.5
Medication: Cholesterol lowering	0.1	0.2	0.4	0.7	-0.0
Impedance of arm (left)	0.1	0.4	0.8	0.9	0.3
Peak expiratory flow (PEF)	0.1	0.2	0.3	0.4	-0.5
Medication: Amlodipine	0.1	0.2	0.3	-0.3	0.6
Health satisfaction	0.1	0.2	0.3	0.1	-0.6
Emphysema/chronic bronchitis	0.1	0.1	0.1	0.3	0.3
Angina (self-reported)	0.1	0.1	0.1	-0.4	0.1
Medication: Ibuprofen	0.1	0.2	0.3	-0.5	0.2
Alcohol intake frequency.	0.1	0.2	0.3	-0.5	0.4
Number of full sisters	0.1	0.1	0.2	0.4	0.0
Age at last live birth	0.1	0.2	0.3	0.3	0.6
Leg pain on walking	0.1	0.1	0.3	-0.0	-0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.4	0.6	-0.1
Breast cancer (self-reported)	0.1	0.1	0.1	-0.1	0.4
Osteoporosis (self-reported)	0.1	0.2	0.3	0.0	0.6
Miserableness	0.1	0.2	0.5	-0.7	-0.1
Medication: Bendroflumethiazide	0.1	0.1	0.3	0.5	-0.1
Average weekly beer plus cider intake	0.1	0.1	0.1	-0.1	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.4	0.2
Impedance of whole body	0.1	0.3	0.6	0.8	-0.3
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.2
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.2	0.4	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.0	0.0	-0.0	-0.2
Allergy or Eczema	0.0	0.0	0.0	-0.2	0.2
Hair Pigment	0.0	0.4	0.6	0.8	0.5
Angina	0.0	0.0	0.0	-0.2	-0.0
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.1	0.2
Diabetes (mother)	0.0	0.0	0.0	0.1	-0.0
Hand grip strength (right)	0.0	0.1	0.2	0.0	-0.4
Townsend deprivation index at recruitment	0.0	0.1	0.1	0.3	-0.1
Current tobacco smoking	0.0	0.0	0.0	0.0	-0.1
Taking other prescription medications	0.0	0.1	0.1	0.3	0.1
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	0.1	0.2
Impedance of leg (left)	0.0	0.1	0.1	0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.2	0.1
Illnesses of mother	0.0	0.0	0.0	-0.1	-0.1
Exposure to tobacco smoke at home	0.0	0.0	0.0	-0.1	0.2
Blood clot in the leg (DVT)	0.0	0.0	0.1	-0.3	0.1
Worry too long after embarrassment	0.0	0.1	0.1	-0.1	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	0.1	-0.1
Pulse wave peak to peak time	0.0	0.0	0.0	-0.1	0.0
Medication: Blood pressure	0.0	0.0	0.0	0.0	0.2
Overall health rating	0.0	0.1	0.1	0.2	0.3
Loneliness, isolation	0.0	0.0	0.0	-0.1	-0.1
Long-standing illness, disability or infirmity	0.0	0.1	0.1	-0.1	0.3
Qualifications: nursing, teaching	0.0	0.1	0.1	-0.2	0.3
Eye problems/disorders: Cataract	0.0	0.1	0.1	0.3	-0.1
Medication: Gliclazide	0.0	0.0	0.0	-0.2	0.0
Smoking status: Current	0.0	0.0	0.0	-0.1	0.2
Financial situation satisfaction	0.0	0.0	0.0	0.2	0.2
High cholesterol (Self-reported)	0.0	0.1	0.2	0.4	-0.1
Risk taking	0.0	0.1	0.1	-0.3	-0.0
Cholesterol lowering medication	0.0	0.0	0.0	0.2	0.2
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	-0.2	0.2

Hub : Genes

C16orf59

Models

Trait associations