TWAS hub - C19orf33

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0380	0.0210	2.9e-04	0.038	0.039	0.018	NA	0.021	3.7e-04	2.9e-04	9.8e-03	NA	6.4e-03
2	TCGA	Breast Invasive Carcinoma	0.0160	0.0100	2.9e-03	0.016	0.011	0.002	NA	0.013	2.1e-04	1.8e-03	9.4e-02	NA	9.6e-04
3	TCGA	Colon Adenocarcinoma	0.1050	0.0460	1.8e-07	0.080	0.110	0.084	NA	0.084	2.4e-05	6.6e-07	1.5e-05	NA	1.4e-05
4	TCGA	Esophageal Carcinoma	0.1980	0.0860	2.3e-06	0.218	0.172	0.184	NA	0.192	1.6e-07	3.9e-06	1.8e-06	NA	9.8e-07
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.0751	0.0298	3.6e-12	0.110	0.114	0.121	NA	0.122	2.5e-12	1.0e-12	2.0e-13	NA	1.3e-13
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0282	0.0143	4.7e-05	0.038	0.037	0.031	NA	0.034	3.5e-05	4.2e-05	1.8e-04	NA	9.3e-05
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0550	0.0290	7.8e-04	0.066	0.035	0.041	NA	0.038	1.2e-04	4.1e-03	2.2e-03	NA	3.1e-03
8	TCGA	Lung Adenocarcinoma	0.0909	0.0346	2.8e-15	0.132	0.142	0.112	NA	0.135	3.9e-15	3.0e-16	5.7e-13	NA	1.8e-15
9	TCGA	Lung Squamous Cell Carcinoma	0.0288	0.0160	7.9e-04	0.021	0.020	0.017	NA	0.021	1.6e-03	2.3e-03	3.9e-03	NA	1.7e-03
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.1760	0.0690	8.4e-10	0.144	0.137	0.157	NA	0.157	6.0e-10	1.5e-09	9.3e-11	NA	8.3e-11
11	TCGA	Pancreatic Adenocarcinoma	0.1190	0.0580	3.9e-04	0.096	0.087	0.066	NA	0.088	8.0e-05	1.7e-04	9.8e-04	NA	1.6e-04
12	TCGA	Pheochromocytoma and Paraganglioma	0.1880	0.0700	1.1e-07	0.116	0.131	0.127	NA	0.114	2.5e-05	6.9e-06	1.0e-05	NA	2.9e-05
13	TCGA	Prostate Adenocarcinoma	0.0788	0.0309	3.2e-13	0.134	0.133	0.122	NA	0.128	6.7e-14	9.2e-14	1.0e-12	NA	2.7e-13
14	TCGA	Rectum Adenocarcinoma	0.1960	0.0870	3.8e-05	0.191	0.186	0.187	NA	0.213	3.0e-05	3.9e-05	3.7e-05	NA	1.0e-05
15	TCGA	Skin Cutaneous Melanoma	0.0830	0.0500	7.2e-03	0.058	0.045	0.052	NA	0.037	1.2e-02	2.3e-02	1.6e-02	NA	3.6e-02
16	TCGA	Stomach Adenocarcinoma	0.0710	0.0300	1.5e-07	0.113	0.102	0.103	NA	0.100	1.6e-08	8.6e-08	7.3e-08	NA	1.1e-07
17	TCGA	Testicular Germ Cell Tumors	0.0910	0.0500	9.7e-04	0.062	0.090	0.078	NA	0.075	3.1e-03	4.4e-04	1.1e-03	NA	1.3e-03
18	TCGA	Thyroid Carcinoma	0.1060	0.0470	2.9e-11	0.099	0.106	0.109	NA	0.111	7.0e-10	1.6e-10	9.2e-11	NA	6.6e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Blood Platelet Count	9.1	105.2	169.0	-10.3	-11.7	-10.7	-10.3	-9.8	-10.9	-8.9	-8.5	-9.5	-11.2	-10.7	-7.2	-10.7	-9.9	-13.0	-10.4	-10.2	-9.3
Length of working week for main job	5.0	5.5	10.2	2.3	-0.4	1.9	2.6	2.7	2.4	2.5	2.6	3.0	1.5	2.1	3.2	2.4	2.1	0.2	2.6	2.5	2.6
Deep venous thrombosis (DVT) (self-reported)	4.7	6.1	8.3	2.5	1.9	2.6	1.4	2.5	2.5	2.3	2.7	2.7	2.9	2.8	2.4	2.5	2.6	1.8	2.5	2.6	2.6
Had other major operations	4.4	5.3	7.4	2.4	2.1	2.4	1.5	2.3	2.4	2.1	2.5	2.5	2.6	2.7	2.1	2.4	2.4	1.9	2.4	2.4	2.2
Time employed in main current job	4.1	4.7	6.6	-2.3	-1.8	-2.6	-1.8	-2.1	-2.2	-2.2	-1.9	-2.0	-2.3	-2.4	-1.8	-2.4	-2.6	-1.7	-2.1	-2.2	-2.5
Blood clot in the leg (DVT)	3.9	5.0	7.0	2.3	2.0	2.4	1.2	2.3	2.3	2.0	2.4	2.4	2.6	2.6	2.1	2.3	2.3	1.7	2.2	2.4	2.4
Eye problems/disorders: Cataract	3.9	4.6	6.8	2.0	2.1	2.2	1.9	2.2	2.2	2.1	1.9	1.9	1.7	2.2	1.8	2.0	2.4	2.6	2.3	2.2	2.4
Qualifications: College or University degree	3.7	11.6	14.9	3.4	3.0	3.6	3.3	3.5	3.4	3.0	3.0	3.1	3.9	3.8	2.9	3.7	3.5	3.5	3.7	3.4	3.4
Ever had hysterectomy (womb removed)	3.4	3.8	8.5	2.0	2.9	2.2	1.9	1.7	2.2	1.8	1.7	2.0	1.5	1.9	1.4	1.9	1.9	2.0	1.7	2.0	1.9
Medication: Atorvastatin	3.1	3.8	7.7	-1.9	-2.8	-2.1	-1.9	-1.8	-2.0	-1.4	-1.7	-1.8	-2.1	-2.0	-1.5	-2.0	-1.8	-2.4	-2.3	-1.9	-1.7
Medication: Co-codamol	2.8	3.2	5.3	1.8	-0.4	1.8	1.1	2.3	1.7	2.3	2.0	1.9	1.8	1.9	2.1	2.0	2.0	0.4	1.8	1.9	1.7
Medication: Atenolol	2.6	3.2	7.3	-1.6	-1.4	-1.7	-2.0	-2.0	-1.8	-1.9	-1.4	-1.4	-1.9	-2.0	-1.2	-1.7	-2.0	-2.7	-2.0	-1.7	-1.5
Nervous feelings	2.6	4.8	9.8	-2.3	-2.0	-2.4	-3.1	-2.1	-2.3	-2.0	-1.7	-1.9	-2.2	-2.0	-1.9	-2.5	-2.2	-2.0	-2.4	-2.2	-1.9
Medication for cholesterol	2.6	3.9	5.9	-1.9	-2.1	-2.1	-1.6	-1.7	-2.1	-1.5	-1.6	-2.0	-2.1	-2.4	-1.4	-2.1	-2.0	-2.2	-2.0	-2.0	-2.3
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	6.0	-2.0	-0.8	-1.4	-1.3	-2.1	-1.9	-2.2	-2.5	-2.3	-1.8	-1.7	-1.9	-1.5	-1.9	-1.1	-1.6	-1.9	-1.1
Breast cancer (self-reported)	2.5	3.0	4.0	-1.8	-1.6	-1.9	-1.7	-1.8	-1.7	-1.7	-1.7	-1.5	-1.4	-1.6	-1.8	-1.7	-1.8	-1.1	-2.0	-1.8	-2.0
Age started oral contraceptive pill	2.5	3.2	5.4	1.7	0.6	1.7	1.7	1.8	1.6	1.5	1.7	1.5	1.8	2.1	1.8	1.9	2.1	1.5	2.3	1.8	2.3
Ever used hormone-replacement therapy (HRT)	2.4	3.1	5.7	1.9	2.0	1.6	1.1	1.8	1.7	1.8	1.9	1.8	1.9	1.9	1.2	1.5	1.9	2.4	1.7	1.7	1.4
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	17.0	1.1	3.5	1.2	1.6	0.9	1.5	0.7	0.5	0.8	1.4	1.2	-0.2	1.0	1.1	4.1	1.4	1.1	1.0
Prospective memory result	2.3	2.9	6.5	-1.4	-1.1	-1.7	-2.2	-1.6	-1.8	-1.5	-1.0	-1.4	-1.8	-1.8	-1.1	-1.8	-1.9	-2.5	-1.8	-1.6	-1.8
Fasting Glucose	2.2	2.6	5.5	-2.0	-0.6	-1.7	-2.0	-1.9	-1.7	-2.3	-1.9	-1.8	-0.7	-0.9	-2.1	-1.6	-1.7	0.1	-1.3	-1.7	-1.1
Bipolar Disorder or Schizophrenia	2.1	5.1	7.4	2.2	2.5	2.4	1.8	2.3	2.3	1.9	1.9	2.3	2.2	2.6	1.6	2.4	2.1	2.7	2.3	2.2	2.6
Eye problems/disorders: Glaucoma	2.1	2.5	6.2	1.6	2.2	1.6	1.5	1.4	1.4	1.2	1.2	1.1	1.5	1.6	0.8	1.4	1.7	2.5	1.8	1.5	1.6
Maternal smoking around birth	2.0	2.9	4.3	1.7	1.8	1.9	2.0	1.8	1.9	1.7	1.2	1.6	1.7	1.6	1.2	1.9	1.6	2.1	1.7	1.7	1.6
Supplements: Fish oil (including cod liver oil)	2.0	2.7	4.1	-1.6	-2.0	-2.0	-1.7	-1.5	-1.8	-1.7	-1.3	-1.4	-1.5	-1.6	-1.2	-1.7	-1.8	-1.5	-1.4	-1.7	-1.7
Mean time to correctly identify matches	1.9	3.7	5.6	-2.0	-0.3	-2.1	-1.5	-2.1	-1.9	-2.4	-2.1	-2.0	-2.1	-2.1	-2.1	-2.1	-2.3	-0.5	-1.7	-2.0	-1.7
Schizophrenia (2018)	1.8	3.8	6.0	2.0	1.9	2.2	1.0	2.0	1.9	1.8	2.0	2.1	1.6	2.4	1.9	2.0	1.9	1.2	1.9	2.0	2.5
Ulcerative Colitis	1.8	2.5	4.0	1.8	1.6	1.6	1.0	1.8	1.7	2.0	1.9	1.9	1.2	1.4	1.3	1.3	1.7	1.7	1.4	1.7	1.3
Smoking Status	1.8	4.2	7.9	2.3	-0.2	1.9	1.0	2.5	2.1	2.8	2.6	2.7	1.6	1.8	2.5	1.8	2.3	0.3	1.8	2.2	2.1
Medication: Cholesterol lowering	1.8	2.8	4.8	-1.6	-1.3	-1.9	-2.0	-1.5	-1.6	-1.2	-1.2	-1.3	-2.2	-2.0	-1.3	-2.0	-1.8	-1.5	-1.8	-1.6	-1.9
Breastfed as a baby	1.7	2.1	3.4	-1.5	-0.5	-1.5	-1.7	-1.8	-1.4	-1.8	-1.4	-1.2	-1.0	-1.2	-1.6	-1.5	-1.7	-1.2	-1.7	-1.5	-1.3
Number of children fathered	1.7	1.9	3.8	1.4	0.1	1.6	1.0	1.7	1.4	1.5	1.3	1.4	2.0	1.4	1.5	1.7	1.2	0.4	1.4	1.4	1.2
Eye problems/disorders: None of the above	1.7	2.0	3.1	-1.5	-1.3	-1.3	-0.9	-1.3	-1.5	-1.3	-1.6	-1.6	-1.0	-1.4	-1.4	-1.1	-1.5	-1.2	-1.5	-1.6	-1.7
Pulse rate, automated reading	1.7	5.4	10.1	-2.1	-1.9	-2.4	-2.9	-2.3	-2.3	-1.9	-1.4	-1.9	-2.7	-2.4	-1.5	-2.7	-2.2	-3.2	-2.6	-2.1	-2.3
Smoking status: Current	1.7	2.7	5.0	1.6	-0.7	1.5	1.1	2.0	1.7	2.2	2.0	2.0	1.2	1.5	2.1	1.4	1.8	-0.0	1.4	1.7	1.9
Number of self-reported non-cancer illnesses	1.7	2.9	4.6	1.7	0.2	1.8	0.6	1.8	1.7	1.4	2.0	2.1	2.0	2.1	2.1	1.9	1.6	0.2	1.7	1.8	2.0
Reaction Time	1.6	3.1	4.6	-1.9	-0.7	-2.1	-1.3	-1.8	-1.7	-1.9	-1.9	-1.8	-2.1	-2.0	-1.8	-2.1	-2.1	-0.4	-1.6	-1.8	-1.6
Ever highly irritable/argumentative for 2 days	1.6	2.0	3.1	1.7	0.3	1.6	0.3	1.5	1.3	1.6	1.8	1.8	1.3	1.6	1.7	1.5	1.6	-0.4	1.0	1.4	1.4
Angina (self-reported)	1.6	2.1	6.4	-1.4	-2.5	-1.7	-1.3	-1.0	-1.5	-0.9	-0.8	-1.1	-2.0	-1.7	-0.5	-1.6	-1.2	-2.1	-1.0	-1.2	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	4.2	1.3	-1.0	1.2	1.0	1.5	1.3	1.5	1.5	1.8	0.9	1.2	2.1	1.4	1.3	-0.6	1.3	1.4	1.9
Irritability	1.6	2.7	5.5	1.6	2.0	1.9	2.1	1.8	1.9	1.8	1.0	1.4	1.1	1.3	1.1	1.7	1.5	2.3	1.6	1.6	1.6
Schizophrenia (2014)	1.5	3.3	5.1	1.8	1.4	2.0	1.1	1.9	1.9	1.8	1.8	2.0	1.5	2.2	1.7	1.9	1.9	1.5	1.7	1.9	2.2
Noisy workplace	1.5	1.8	7.2	-1.3	-2.7	-1.3	-1.6	-0.8	-1.2	-0.8	-0.8	-0.6	-1.6	-1.4	-0.4	-1.2	-1.4	-2.3	-1.1	-1.1	-0.8
Number of full brothers	1.5	1.9	2.9	1.5	1.1	1.6	0.4	1.5	1.3	1.4	1.5	1.5	1.6	1.7	1.2	1.5	1.5	0.5	1.2	1.4	1.4
Worry too long after embarrassment	1.5	2.5	7.1	-1.4	-1.2	-1.8	-2.7	-1.6	-1.6	-1.3	-0.7	-1.0	-1.5	-1.3	-1.2	-2.0	-1.4	-1.7	-1.9	-1.5	-1.6
Illnesses of father: Heart disease	1.5	2.1	3.6	-1.4	-1.7	-1.3	-1.7	-1.4	-1.5	-1.2	-1.1	-1.3	-1.3	-1.5	-1.1	-1.4	-1.4	-1.9	-1.6	-1.3	-1.6
Leg fat percentage (left)	1.5	5.6	10.3	2.7	0.2	2.3	0.6	3.2	2.2	3.1	3.1	2.9	2.3	2.3	2.8	2.4	2.3	0.2	2.2	2.5	2.0
Irritable Bowel Disease (IBD)	1.4	3.4	9.6	1.7	2.9	1.9	1.7	1.7	1.9	1.6	1.3	1.7	1.7	1.9	0.7	1.8	1.7	3.1	1.6	1.7	1.4
Worrier / anxious feelings	1.4	2.7	5.8	-1.5	-1.7	-1.6	-2.0	-1.7	-1.7	-1.4	-1.1	-1.3	-2.0	-1.7	-0.9	-1.8	-1.5	-2.4	-1.8	-1.5	-1.1
Number of live births	1.4	2.0	5.9	1.1	1.9	1.8	0.5	1.0	1.3	0.5	0.7	1.2	2.4	2.1	0.5	1.8	1.2	1.6	1.2	1.1	1.5
Pulse rate	1.4	2.4	4.5	-1.4	-0.2	-1.5	-1.7	-1.6	-1.6	-1.4	-1.2	-1.5	-1.5	-1.8	-1.6	-1.8	-1.6	-1.1	-1.8	-1.6	-2.1
Loneliness, isolation	1.4	1.9	2.9	1.5	1.1	1.5	0.6	1.5	1.5	1.5	1.5	1.7	1.3	1.4	1.2	1.3	1.4	1.5	1.3	1.5	1.3
Medication: Lisinopril	1.4	1.9	2.8	1.5	1.2	1.6	1.1	1.5	1.6	1.4	1.3	1.6	1.7	1.4	1.2	1.6	1.2	0.6	1.1	1.4	1.1
Ulcerative Colitis (UC)	1.3	2.5	4.6	1.5	1.8	1.5	1.3	1.6	1.8	1.6	1.5	1.8	1.4	1.6	1.1	1.4	1.5	2.1	1.4	1.6	1.3
Angina	1.3	1.7	5.7	-1.3	-2.4	-1.6	-1.1	-0.9	-1.3	-0.8	-0.7	-1.0	-1.8	-1.6	-0.4	-1.4	-1.1	-1.9	-0.9	-1.1	-0.8
Tinnitus: Yes, but not now, but have in the past	1.3	1.3	2.7	1.2	0.4	1.5	1.4	1.4	1.2	1.3	0.9	1.0	0.6	0.6	1.6	1.5	0.9	0.1	1.4	1.2	1.2
Past tobacco smoking	1.3	2.3	4.8	-1.7	-0.2	-1.3	-1.2	-1.8	-1.8	-2.2	-2.0	-2.2	-0.5	-0.9	-2.0	-1.2	-1.4	-0.2	-1.3	-1.7	-1.5
Pulse wave peak to peak time	1.3	1.5	2.6	1.2	0.1	1.2	1.1	1.2	1.2	0.9	1.2	1.2	1.6	1.4	1.5	1.4	1.1	0.4	1.5	1.3	1.5
Medication: Ibuprofen	1.3	1.6	3.0	-1.4	-1.2	-0.9	-0.9	-1.4	-1.4	-1.6	-1.7	-1.5	-1.2	-1.1	-1.1	-0.9	-1.3	-1.3	-1.1	-1.4	-0.7
Hypertension (Self-reported)	1.3	3.5	6.3	2.0	1.4	2.0	0.7	1.8	2.1	1.6	2.1	2.5	1.7	2.2	1.9	1.8	1.7	0.9	1.7	2.1	2.4
Worry (Nagel 2018)	1.2	2.6	7.6	-1.7	-1.3	-1.7	-2.8	-1.5	-1.8	-1.5	-1.1	-1.3	-1.5	-1.3	-1.4	-1.8	-1.5	-1.6	-1.7	-1.6	-1.3
Major Depression (MDD)	1.2	1.4	2.9	1.3	1.5	1.4	0.8	0.9	0.9	0.8	1.3	0.8	1.6	1.7	1.1	1.3	1.5	0.2	1.1	1.1	1.1
Systolic blood pressure, automated reading	1.2	3.6	9.2	2.2	3.0	2.4	1.7	1.6	2.2	1.7	1.6	1.9	1.9	1.7	1.1	2.0	1.7	2.0	1.4	1.9	1.4
Waist circumference	1.2	4.5	8.1	2.3	-0.2	1.8	1.0	2.8	2.2	2.6	2.7	2.8	2.2	2.1	2.5	2.1	1.9	0.4	2.0	2.3	2.0
Hair/balding pattern: Pattern 4	1.2	2.8	6.2	-1.7	-1.4	-2.0	-1.6	-1.6	-1.5	-1.2	-1.3	-1.3	-2.5	-2.2	-1.3	-2.1	-1.8	-1.3	-1.8	-1.6	-1.6
Leg fat percentage (right)	1.2	4.4	8.6	2.4	-0.0	1.9	0.4	2.9	2.0	2.9	2.9	2.8	1.9	1.8	2.6	2.0	1.9	-0.0	1.9	2.2	1.6
Medication: Allopurinol	1.2	1.7	4.1	1.4	-0.1	1.1	0.1	1.5	1.1	1.3	1.8	1.6	2.0	1.7	1.3	1.2	1.3	0.3	1.2	1.3	0.8
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.4	-1.0	-0.1	-1.0	-1.5	-1.1	-1.2	-1.0	-1.0	-1.1	-1.3	-1.2	-1.4	-1.2	-1.3	-0.9	-1.4	-1.2	-1.6
Osteoarthritis (self-reported)	1.2	1.6	6.1	-1.3	-2.5	-1.3	-0.8	-0.8	-1.2	-1.0	-1.2	-1.1	-0.8	-1.4	-0.7	-1.0	-1.6	-1.4	-0.9	-1.2	-1.3
Medication: Blood pressure	1.2	2.2	3.7	1.5	0.9	1.8	0.5	1.4	1.5	1.3	1.6	1.6	1.6	1.9	1.5	1.6	1.7	0.6	1.4	1.6	1.9
Fractured/broken bones in last 5 years	1.2	1.5	5.3	1.1	2.3	1.4	0.9	0.8	1.1	0.6	0.9	0.9	1.1	1.4	0.8	1.2	1.2	1.3	1.3	1.2	1.5
Bipolar Disorder (2018)	1.1	1.7	7.7	1.0	1.7	1.1	1.7	1.1	1.3	0.8	0.5	1.0	1.5	1.3	0.2	1.3	1.0	2.8	1.3	1.1	1.0
Neuroticism	1.1	2.8	8.1	-1.6	-1.5	-1.7	-2.9	-1.6	-1.6	-1.4	-0.8	-1.1	-1.8	-1.4	-1.1	-2.0	-1.5	-2.1	-1.9	-1.5	-1.4
Diabetes (father)	1.1	1.4	3.6	1.0	-0.2	1.6	1.4	1.2	0.8	0.8	0.6	0.4	1.8	1.3	1.2	1.9	1.3	0.3	1.5	1.0	1.0
Trunk fat mass	1.1	4.9	8.7	2.4	0.1	2.2	0.8	2.9	2.2	2.7	2.8	2.8	2.5	2.4	2.5	2.3	2.1	0.4	2.1	2.3	1.9
Arm fat percentage (right)	1.1	4.2	8.0	2.3	-0.0	1.9	0.5	2.8	1.9	2.7	2.8	2.6	2.4	2.1	2.4	2.1	1.9	0.1	1.8	2.1	1.4
Arm fat mass (right)	1.1	4.5	8.3	2.3	-0.3	1.9	0.4	2.9	1.9	2.7	2.9	2.7	2.5	2.2	2.5	2.1	1.9	-0.1	1.8	2.1	1.5
Gout (self-reported)	1.1	1.5	3.3	1.3	-0.4	1.1	0.8	1.4	1.0	1.3	1.5	1.3	1.8	1.6	1.4	1.3	1.4	-0.1	1.2	1.2	0.9
Body fat percentage	1.1	4.3	7.9	2.3	0.2	2.1	0.4	2.8	2.0	2.6	2.6	2.6	2.3	2.1	2.3	2.2	1.9	0.2	1.9	2.1	1.8
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.7	1.0	-0.3	0.9	-0.0	1.1	0.8	0.9	1.5	1.3	1.6	1.6	1.3	1.0	1.3	-0.1	1.2	1.0	1.5
Average weekly red wine intake	1.1	1.6	3.7	1.0	1.6	1.3	0.7	1.0	1.0	0.5	0.8	0.8	1.8	1.9	0.5	1.3	1.2	1.9	1.3	1.1	1.4
Number of operations (self-reported)	1.1	1.6	2.9	1.0	0.6	1.2	0.8	1.3	1.3	1.0	0.9	1.5	1.6	1.6	0.7	1.3	1.2	1.7	1.3	1.2	1.6
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.7	1.2	0.4	1.3	0.5	1.3	1.0	1.1	1.3	1.1	1.6	1.5	1.2	1.4	1.1	0.3	1.1	1.1	0.8
Leg fat mass (left)	1.1	4.4	8.6	2.3	-0.2	1.9	0.4	2.9	2.0	2.8	2.8	2.8	2.2	2.0	2.5	2.1	1.9	0.1	1.9	2.2	1.6
Systolic Blood Pressure	1.0	5.2	15.1	2.4	3.9	2.8	1.7	1.9	2.5	2.1	1.8	2.0	1.7	2.0	1.2	2.1	2.3	3.0	1.8	2.4	2.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.7	-0.8	-1.3	-1.2	-1.9	-1.0	-0.9	-0.8	-0.0	-0.4	-0.7	-0.7	-0.3	-1.2	-0.9	-1.8	-1.0	-0.8	-0.7
Trunk fat percentage	1.0	3.9	6.6	2.1	0.4	2.0	0.5	2.6	1.9	2.4	2.3	2.4	2.4	2.2	2.1	2.2	1.8	0.5	1.7	2.0	1.8
Current tobacco smoking	1.0	1.6	3.0	1.2	-0.8	1.1	0.8	1.5	1.3	1.7	1.5	1.6	0.9	1.1	1.6	1.0	1.4	-0.2	1.0	1.3	1.5
Illnesses of mother	1.0	1.2	2.4	1.1	0.7	1.0	1.5	1.2	1.2	1.5	1.2	1.0	0.5	0.9	1.2	1.0	1.4	1.0	1.1	1.2	0.8
Leg fat mass (right)	1.0	3.9	7.7	2.2	-0.4	1.7	0.2	2.8	1.9	2.7	2.7	2.7	1.9	1.8	2.5	1.8	1.7	-0.2	1.7	2.0	1.4
Arm fat percentage (left)	1.0	3.9	7.3	2.2	-0.4	1.8	0.3	2.7	1.8	2.5	2.6	2.6	2.3	2.0	2.4	2.1	1.8	-0.3	1.7	2.0	1.4
Mouth/teeth dental problems: Mouth ulcers	1.0	1.5	5.9	-1.2	-0.4	-0.8	-2.4	-1.2	-1.3	-1.7	-1.0	-1.2	-0.1	-0.5	-1.2	-0.8	-1.4	-1.3	-1.3	-1.2	-1.2
Ever depressed for a whole week	1.0	1.3	2.2	-1.0	-0.5	-1.1	-1.3	-1.2	-1.1	-1.1	-0.9	-1.0	-1.5	-1.4	-0.8	-1.3	-1.3	-1.3	-1.2	-1.1	-0.8
Alzheimer’s Disease (in mother)	0.9	1.1	3.3	-0.6	1.8	-0.5	-0.2	-1.2	-0.5	-1.3	-1.2	-1.1	-0.2	-0.9	-1.6	-0.7	-1.2	0.9	-1.0	-0.8	-1.4
Sensitivity / hurt feelings	0.9	1.6	5.5	-1.1	-1.4	-1.4	-2.4	-0.9	-1.3	-0.7	-0.5	-0.8	-1.7	-1.1	-0.7	-1.6	-1.0	-1.6	-1.3	-1.0	-0.7
Qualifications: CSEs or equivalent	0.9	1.2	3.1	-1.1	-0.9	-1.1	-1.8	-1.0	-1.2	-1.1	-0.9	-1.0	-0.4	-0.9	-1.1	-0.9	-1.2	-1.0	-1.2	-1.2	-1.5
High blood pressure	0.9	2.5	5.0	1.7	1.2	1.7	0.6	1.5	1.8	1.4	1.8	2.2	1.1	1.7	1.7	1.5	1.4	0.5	1.3	1.8	2.2
Health satisfaction	0.9	1.2	7.1	-0.6	-1.9	-0.6	-1.3	-0.7	-0.9	-0.8	-0.6	-0.4	-0.3	-0.8	-0.1	-0.4	-1.2	-2.7	-1.2	-0.9	-1.0
Whole body fat mass	0.9	3.8	7.2	2.1	-0.4	1.8	0.3	2.7	1.8	2.5	2.6	2.6	2.2	2.0	2.4	2.0	1.7	-0.1	1.8	2.0	1.6
Arm fat mass (left)	0.9	3.7	7.1	2.1	-0.6	1.7	0.3	2.7	1.7	2.5	2.6	2.6	2.1	1.9	2.4	1.9	1.7	-0.5	1.6	1.9	1.4
Hearing aid user	0.9	1.0	1.8	-0.9	0.1	-0.8	-1.3	-1.1	-0.9	-0.8	-0.9	-1.0	-1.2	-1.1	-1.1	-1.1	-1.0	-0.8	-1.4	-1.0	-0.9
Alzheimer’s Disease (in father)	0.8	0.9	1.7	-1.0	-1.0	-1.2	-0.6	-0.8	-1.1	-0.7	-0.9	-0.9	-0.9	-1.0	-1.0	-1.0	-0.9	-0.5	-1.0	-1.1	-1.3
Body Mass Index (BMI) (2010)	0.8	1.1	2.2	0.9	1.2	1.0	0.6	0.9	0.9	0.4	0.9	0.9	1.4	1.5	0.7	1.0	0.9	1.3	1.2	1.0	1.2
Mean Putamen Volume	0.8	0.9	2.4	-1.1	-0.6	-0.7	-0.6	-1.1	-1.0	-1.4	-1.5	-1.2	-0.1	-0.6	-1.2	-0.5	-1.1	-0.3	-0.9	-1.2	-0.8
Allergy or Eczema	0.8	2.2	5.0	-1.7	0.5	-0.8	-1.5	-1.8	-1.5	-2.1	-2.2	-2.0	-0.3	-0.7	-2.2	-0.9	-1.4	0.2	-1.4	-1.6	-1.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.5	0.8	1.3	1.2	0.9	0.8	1.0	0.6	0.5	0.8	1.3	1.3	0.5	1.2	1.0	1.6	1.1	0.9	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.7	-0.8	-0.4	-1.1	-1.0	-1.2	-1.1	-0.8	-0.7	-1.1	-1.1	-1.1	-1.1	-1.3	-0.6	-0.5	-1.1	-1.0	-1.1
Ever had bowel cancer screening	0.8	0.9	4.3	-0.5	2.1	-0.1	0.1	-0.8	-0.3	-1.1	-1.3	-0.9	-0.3	-0.5	-1.5	-0.3	-0.8	1.6	-0.5	-0.6	-0.5
Osteoporosis (self-reported)	0.8	1.0	2.6	0.9	0.6	0.8	1.2	1.0	1.2	1.0	0.8	1.3	0.7	0.9	0.6	0.8	1.0	1.6	1.1	1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.5	-1.3	-0.6	-1.4	-1.5	-1.3	-1.3	-1.2	-1.1	-1.4	-0.9	-1.1	-1.4	-1.4	-1.1	-0.5	-1.3	-1.3	-1.6
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.7	-1.5	0.3	-0.7	-1.3	-1.6	-1.3	-1.9	-1.9	-1.7	-0.3	-0.5	-1.8	-0.7	-1.2	-0.0	-1.3	-1.4	-1.0
Weight	0.7	3.6	6.8	2.1	-0.4	1.6	0.7	2.6	1.8	2.5	2.5	2.5	1.9	1.9	2.4	1.8	1.7	-0.0	1.7	1.9	1.5
Hip circumference	0.7	2.9	5.2	1.8	0.2	1.7	0.7	2.1	1.7	2.0	2.1	2.2	2.3	1.9	1.9	1.9	1.5	0.4	1.5	1.7	1.3
Falls in the last year	0.7	0.9	4.5	-0.8	-2.1	-1.1	-1.3	-0.5	-0.8	-0.5	-0.3	-0.2	-0.8	-0.6	-0.3	-0.9	-0.8	-1.6	-0.9	-0.7	-0.4
Glaucoma (self-reported)	0.7	0.8	2.5	0.9	1.3	1.0	0.4	0.8	0.7	0.6	0.7	0.5	1.1	1.1	0.3	0.8	1.1	1.6	1.1	0.8	0.9
Medication: Ventolin 100micrograms inhaler	0.7	0.8	2.0	0.6	0.3	1.0	0.3	0.9	0.5	0.5	0.8	0.5	1.3	1.4	0.9	1.1	1.1	0.8	1.4	0.8	1.3
Emphysema/chronic bronchitis	0.7	0.8	2.0	-1.1	-1.3	-1.0	-1.4	-0.7	-1.0	-0.7	-0.7	-0.9	-0.4	-0.5	-1.0	-0.9	-0.7	-0.5	-0.9	-1.0	-0.9
Knee pain experienced in last month	0.7	1.1	2.1	1.0	1.4	1.4	1.1	1.0	1.2	0.8	0.5	1.0	1.1	1.0	0.6	1.4	0.8	1.2	1.0	1.0	0.9
Commuting to job workplace: Walk	0.7	0.7	3.0	0.8	1.1	0.6	1.6	1.0	0.9	1.0	0.4	0.6	0.4	0.2	0.3	0.7	0.5	1.7	0.8	0.7	-0.0
Medication: Bendroflumethiazide	0.7	1.1	2.5	1.0	0.6	1.1	1.0	0.9	1.0	0.7	0.8	1.0	1.0	1.3	1.1	1.3	1.0	0.5	1.1	1.1	1.6
Average weekly beer plus cider intake	0.7	1.0	2.5	0.7	-1.6	0.6	0.7	1.1	0.9	1.2	1.0	1.2	0.9	0.8	1.4	0.9	0.9	-0.5	0.8	0.9	1.0
Vascular/heart problems diagnosed by doctor	0.7	1.9	4.7	-1.5	-0.7	-1.3	-0.3	-1.4	-1.6	-1.4	-1.9	-2.2	-0.7	-1.3	-1.8	-1.1	-1.2	0.1	-1.1	-1.6	-1.8
Supplements: Calcium	0.7	0.7	1.9	0.8	-0.1	1.0	-0.1	1.0	0.7	0.7	1.0	1.1	1.4	1.1	0.9	1.1	0.7	0.0	0.8	0.8	0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	2.6	1.1	1.1	1.2	1.6	1.2	1.4	1.2	1.0	1.4	0.7	1.3	1.1	1.2	1.2	1.2	1.0	1.3	1.4
Neuroticism (2016)	0.6	0.8	6.2	-0.7	0.1	-0.8	-2.5	-0.8	-1.0	-0.9	-0.1	-0.9	-0.3	-0.2	-0.7	-1.0	-0.4	-0.7	-0.8	-0.7	-0.7
Waist Hip Ratio (WHR)	0.6	2.8	4.3	1.5	0.0	1.5	1.5	2.0	1.9	1.9	1.6	2.0	1.4	1.6	1.7	1.6	1.7	1.2	1.7	1.8	2.1
Cardiovascular Disease	0.6	2.0	3.8	1.5	0.7	1.4	-0.1	1.4	1.4	1.4	1.9	1.9	1.2	1.8	1.7	1.2	1.5	-0.1	1.1	1.6	1.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.2	0.4	-0.4	0.5	-0.1	0.9	0.7	0.6	0.9	1.0	1.5	1.5	0.6	0.7	1.0	1.4	1.1	0.8	0.9
Body mass index (BMI)	0.6	2.7	5.9	1.9	-0.6	1.4	-0.2	2.3	1.4	2.2	2.4	2.3	1.6	1.4	2.2	1.5	1.3	-0.9	1.2	1.6	1.1
Alcohol usually taken with meals	0.6	1.0	2.5	-1.1	0.5	-0.9	-1.0	-1.2	-1.2	-1.6	-1.3	-1.4	-0.2	-0.2	-1.6	-0.8	-0.8	0.9	-0.6	-1.1	-0.7
Hair/balding pattern: Pattern 2	0.6	0.8	1.8	-0.8	0.8	-1.0	-0.4	-1.0	-0.7	-0.9	-0.8	-0.7	-1.3	-1.0	-1.1	-1.2	-1.0	0.2	-1.0	-0.8	-0.8
Heart attack	0.6	0.7	2.1	-0.9	-1.1	-0.9	-1.2	-0.8	-0.8	-0.9	-0.2	-0.5	-1.1	-0.9	-0.0	-1.0	-0.8	-1.5	-0.4	-0.6	-0.3
Pain all over the body in last month	0.6	0.7	2.7	0.9	-0.6	0.3	-1.0	1.0	0.5	1.2	1.7	1.2	0.5	0.5	1.0	0.1	0.7	-0.5	0.5	0.7	0.2
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.2	0.9	0.7	1.2	1.6	1.1	1.1	0.7	0.6	0.8	1.7	1.4	0.9	1.5	1.0	1.8	1.5	1.0	1.1
Depression (self-reported)	0.6	0.7	1.7	0.9	-0.4	0.6	0.3	0.9	0.7	0.7	1.1	1.3	0.9	1.0	1.2	0.8	0.6	-0.3	0.7	0.8	0.7
Pulse wave Arterial Stiffness index	0.6	0.7	1.5	-0.8	0.0	-0.9	-0.7	-0.8	-0.8	-0.5	-0.8	-0.8	-1.2	-1.0	-1.1	-1.0	-0.7	0.0	-1.1	-0.9	-1.0
Peak expiratory flow (PEF)	0.6	1.4	4.4	0.9	1.8	1.0	0.4	0.9	1.1	0.8	1.0	1.1	1.2	1.6	0.4	0.9	1.3	2.1	1.1	1.1	1.5
Loud music exposure frequency	0.6	0.7	1.9	-0.7	-1.3	-0.5	0.0	-0.9	-0.6	-0.6	-1.1	-0.8	-1.0	-1.0	-0.3	-0.4	-0.6	-1.4	-0.9	-0.7	-0.1
Mother’s age at death	0.6	0.7	3.0	-0.7	-1.2	-0.6	0.0	-0.9	-0.9	-0.7	-0.8	-1.0	-1.1	-1.0	-0.1	-0.6	-0.6	-1.7	-0.5	-0.7	-0.4
Ever smoked	0.6	1.0	3.1	1.2	0.3	0.7	0.7	1.2	1.4	1.8	1.5	1.6	-0.2	0.2	1.3	0.4	0.8	0.1	0.5	1.2	0.8
Neuroticism (Nagel 2018)	0.5	1.3	6.0	-1.0	-0.5	-1.0	-2.4	-0.9	-1.3	-0.8	-0.4	-0.7	-1.1	-0.8	-0.9	-1.3	-1.0	-1.3	-1.3	-1.0	-1.1
Alzheimer’s Disease (including proxy)	0.5	0.7	4.1	-0.3	2.0	-0.3	0.3	-0.7	-0.2	-0.9	-0.8	-0.8	0.0	-0.5	-1.3	-0.4	-0.8	1.2	-0.7	-0.5	-1.2
Crohns Disease (2012)	0.5	0.7	5.2	0.5	2.3	0.8	1.0	0.4	0.7	0.2	-0.1	0.3	0.8	0.6	-0.3	0.8	0.3	1.8	0.4	0.4	0.2
HbA1C	0.5	0.6	1.4	0.8	0.4	0.6	-0.3	0.9	0.7	0.9	1.2	1.1	0.5	0.8	0.8	0.4	0.8	0.6	0.7	0.8	0.8
Lupus	0.5	0.7	2.5	0.8	-1.0	0.3	0.3	0.8	0.2	1.1	1.2	0.7	-0.8	0.0	1.5	0.2	0.7	-1.6	0.5	0.7	0.6
BMI	0.5	2.9	7.0	2.0	-0.8	1.4	-0.7	2.2	1.3	2.4	2.6	2.4	1.1	1.1	2.4	1.3	1.3	-1.8	0.9	1.6	1.0
Chronotype (morning person)	0.5	1.2	2.6	-1.1	0.8	-1.3	-0.0	-1.3	-0.7	-1.2	-1.3	-1.1	-1.5	-1.2	-1.6	-1.3	-1.0	1.2	-0.6	-0.9	-0.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.4	0.8	0.7	0.8	-0.3	0.9	0.7	0.4	0.8	1.0	1.2	1.2	0.6	0.9	0.6	1.0	1.1	0.8	1.1
Townsend deprivation index at recruitment	0.5	0.7	1.4	0.8	0.2	0.8	0.8	1.1	1.0	1.2	0.8	0.9	0.7	0.7	0.8	0.9	0.9	0.8	0.8	0.9	0.9
Serious illness, injury or assault to yourself	0.5	0.6	1.8	-0.7	-0.9	-0.1	-1.3	-0.6	-0.8	-1.0	-0.8	-0.6	0.6	0.1	-0.6	0.1	-0.6	-1.2	-0.8	-0.8	-0.6
Number of incorrect matches in round	0.5	0.8	1.5	-0.7	0.7	-0.6	-0.8	-1.1	-1.0	-0.8	-0.8	-1.2	-1.2	-0.9	-0.9	-0.9	-0.7	-0.7	-1.1	-0.9	-1.0
Fluid intelligence score	0.5	1.1	2.9	1.0	1.3	1.2	1.7	0.9	1.3	1.0	0.6	1.1	0.7	1.0	0.8	1.2	0.9	1.0	0.8	1.0	1.1
Asthma	0.5	1.0	2.9	-1.3	-0.9	-0.4	-0.4	-1.0	-1.2	-1.6	-1.7	-1.7	0.4	-0.1	-1.3	-0.1	-0.6	0.2	-0.3	-1.1	-0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.4	-1.0	0.4	-0.5	0.1	-1.2	-0.7	-1.3	-1.5	-1.1	-0.5	-0.5	-1.3	-0.4	-0.9	0.4	-0.9	-0.9	-0.6
Medication: Paracetamol	0.5	0.8	2.7	0.6	-0.8	0.7	-0.5	0.8	0.5	0.6	0.8	1.1	1.0	1.4	0.9	0.8	0.9	-0.4	0.7	0.7	1.6
Headache pain in last month	0.5	0.8	3.3	-1.1	-1.8	-0.8	-1.2	-0.7	-1.0	-1.0	-1.0	-0.7	0.1	-0.1	-0.7	-0.4	-0.8	-0.8	-0.6	-0.9	-0.4
Shortness of breath walking on level ground	0.5	0.5	4.7	-0.0	-2.2	-0.4	-0.1	0.1	0.1	0.2	0.4	0.6	-0.3	-0.2	0.9	-0.1	-0.1	-1.7	-0.0	0.1	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	2.9	0.8	1.7	0.8	1.7	0.7	0.8	0.6	0.5	0.3	0.9	0.3	0.3	0.8	0.5	1.5	0.8	0.6	-0.4
Illnesses of father: High blood pressure	0.5	0.6	1.7	0.6	0.0	0.8	1.3	0.8	1.0	0.7	0.4	0.8	0.4	0.6	0.8	0.9	0.6	0.6	0.9	0.9	0.9
Alcohol drinker status: Never	0.5	0.6	3.7	0.2	1.9	0.7	0.6	-0.0	0.4	-0.3	-0.6	-0.2	1.1	0.4	-0.8	0.8	-0.1	1.8	0.2	0.1	-0.3
Crohns Disease (2017)	0.4	0.8	5.1	0.3	2.1	0.8	1.0	0.4	0.6	0.1	-0.4	0.2	0.7	0.7	-0.6	0.8	0.3	2.2	0.4	0.3	0.3
Ovarian Cancer	0.4	0.5	1.8	0.5	1.1	0.8	0.5	0.3	0.8	0.1	0.0	0.5	0.9	1.0	0.1	0.8	0.6	1.3	0.5	0.6	1.1
Primary Biliary Cirrhosis	0.4	0.6	1.3	0.6	0.9	1.1	0.3	0.6	0.7	0.5	0.2	0.4	1.1	1.0	0.3	1.0	0.8	0.8	0.7	0.6	1.0
Rheumatoid Arthritis	0.4	0.5	1.2	0.6	-0.3	0.5	0.9	0.8	0.6	0.8	0.8	0.7	0.0	0.6	1.1	0.5	0.9	0.2	1.0	0.8	1.0
Number of treatments/medications taken	0.4	0.8	2.0	0.6	-0.3	0.9	-0.8	0.8	0.6	0.3	0.9	1.2	1.3	1.4	0.9	1.0	0.6	-0.3	0.7	0.8	1.1
Hearing difficulty/problems: Yes	0.4	0.5	1.7	0.8	0.2	0.8	-0.2	0.9	0.6	0.6	0.9	0.8	1.3	0.9	0.7	0.8	0.6	0.3	0.8	0.7	0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.8	-0.4	1.2	-0.1	0.2	-0.4	0.1	-0.7	-0.9	-0.1	0.4	0.1	-1.2	0.1	-0.5	1.7	-0.3	-0.3	-0.4
Supplements: Glucosamine	0.4	0.5	1.1	-0.6	-0.9	-0.8	-0.1	-0.6	-0.6	-0.5	-0.4	-0.4	-0.8	-0.8	-0.2	-0.6	-0.8	-1.1	-0.7	-0.6	-0.9
Financial difficulties in last 2 years	0.4	0.5	1.5	-0.6	0.1	-0.6	-0.8	-0.6	-0.3	-0.8	-0.8	-0.2	-0.2	-0.8	-1.1	-0.6	-1.2	0.4	-0.9	-0.7	-1.2
Allergy	0.4	0.9	2.2	1.1	-0.4	0.1	1.1	1.1	0.9	1.5	1.5	1.4	-0.6	-0.2	1.5	0.1	0.6	-0.3	0.8	0.9	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.9	-0.6	-1.6	-0.8	-1.7	-0.2	-0.7	-0.4	0.0	-0.2	-0.8	-0.5	0.0	-0.8	-0.6	-1.1	-0.4	-0.4	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.6	0.7	-0.2	0.5	-0.1	0.7	0.8	0.7	1.1	1.1	0.2	0.7	1.2	0.4	0.7	0.0	0.8	0.9	1.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.5	-0.6	-0.8	-0.6	-1.2	-0.5	-0.6	-0.4	-0.4	-0.5	-0.7	-0.6	-0.5	-0.8	-0.6	-0.9	-0.9	-0.6	-0.5
Medication: Amlodipine	0.4	0.6	1.8	0.4	-0.1	0.5	1.0	0.7	0.8	0.8	0.7	0.9	0.1	0.7	0.9	0.5	0.8	0.4	0.8	0.8	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.3	0.7	-0.1	0.7	0.4	0.4	0.7	0.5	0.8	0.8	-0.0	0.7	1.2	0.5	0.8	-0.4	0.7	0.9	1.5
Age at first live birth	0.4	0.6	1.9	0.6	1.4	1.0	1.0	0.2	0.4	0.0	-0.0	-0.0	1.3	1.0	0.0	1.1	0.8	1.2	0.7	0.4	0.7
Medication: Seretide 50 evohaler	0.4	0.4	1.6	0.3	0.2	0.4	0.4	0.6	0.5	0.2	0.4	0.5	1.3	1.0	0.2	0.7	0.6	1.2	0.8	0.5	0.7
Heart disease (mother)	0.4	0.5	2.0	0.5	-1.4	0.0	0.2	1.0	0.4	0.9	0.9	0.9	0.3	0.4	0.9	0.3	0.5	-0.2	0.7	0.5	0.5
Suffer from ‘nerves’	0.4	0.6	2.7	-0.6	-1.5	-0.9	-1.6	-0.4	-0.7	-0.4	0.1	-0.1	-0.5	-0.3	-0.0	-0.8	-0.5	-1.5	-0.7	-0.5	-0.5
Leg pain on walking	0.4	0.5	1.3	0.6	-1.0	0.9	0.4	0.8	0.5	0.9	0.5	0.5	0.8	0.3	1.0	1.0	0.5	-1.1	0.3	0.5	0.3
Smoking status: Previous	0.4	0.6	1.4	0.9	0.0	0.6	0.5	0.9	0.9	1.1	1.1	1.2	0.3	0.3	1.1	0.6	0.7	-0.3	0.5	0.8	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.9	0.7	1.4	0.8	0.1	0.3	0.8	0.6	0.6	0.9	0.0	0.5	0.4	0.4	0.5	0.2	0.1	0.7	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.5	0.5	0.2	0.5	-0.6	0.6	0.5	0.4	1.0	1.0	0.8	1.2	0.6	0.4	0.7	0.3	0.6	0.7	1.1
Asthma (self-reported)	0.4	0.8	2.6	-1.2	-0.7	-0.3	-0.4	-0.9	-1.1	-1.4	-1.6	-1.6	0.5	0.0	-1.2	0.0	-0.5	0.2	-0.2	-1.0	-0.4
Medication: Gliclazide	0.4	0.4	2.5	0.3	1.6	0.5	-0.3	0.3	0.6	0.3	0.3	0.4	0.6	0.7	-0.3	0.3	0.5	1.4	0.2	0.4	0.6
Financial situation satisfaction	0.4	0.4	2.5	-0.2	1.6	-0.2	0.1	-0.7	-0.1	-0.7	-0.6	-0.4	-0.2	-0.7	-0.9	-0.3	-0.9	0.3	-0.6	-0.4	-1.0
Bipolar Disorder (2011)	0.3	0.3	2.1	-0.2	1.3	0.1	-0.0	-0.1	0.1	-0.3	-0.4	-0.2	-0.0	0.2	-0.6	-0.1	0.0	1.5	0.1	0.0	0.2
Respiratory disease	0.3	0.6	2.0	-0.8	-0.0	0.2	-0.3	-0.5	-0.5	-1.0	-1.2	-1.1	1.3	0.7	-1.2	0.5	0.0	1.4	0.1	-0.6	-0.0
Supplements: Zinc	0.3	0.3	0.7	-0.5	-0.4	-0.4	-0.5	-0.5	-0.3	-0.3	-0.5	-0.3	-0.4	-0.7	-0.5	-0.5	-0.7	-0.5	-0.9	-0.5	-0.8
Average weekly fortified wine intake	0.3	0.4	3.8	-0.2	1.0	-0.1	0.4	-0.1	0.3	-0.4	-0.3	0.3	-0.1	0.2	-0.6	-0.1	-0.1	1.9	0.5	0.1	0.7
Taking other prescription medications	0.3	0.4	1.2	0.4	0.5	0.4	-1.1	0.2	0.4	0.1	0.9	0.9	1.1	1.1	0.4	0.3	0.5	-0.1	0.3	0.5	0.8
Stomach or abdominal pain in last month	0.3	0.3	1.1	0.3	1.0	0.8	0.1	0.4	0.5	0.0	0.0	0.4	0.9	0.7	-0.0	0.7	0.2	1.1	0.6	0.4	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.4	0.5	0.6	0.5	-0.5	0.7	0.6	0.5	0.9	0.9	0.7	0.8	0.5	0.4	0.6	1.2	0.8	0.7	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.0	-1.0	-0.5	-0.9	-1.0	-0.9	-0.9	-0.9	-0.8	-0.8	-0.5	-0.6	-0.9	-0.9	-0.8	-0.2	-0.8	-0.9	-1.0
Diabetes (self-reported)	0.3	0.4	0.9	0.7	0.4	0.7	-0.1	0.7	0.8	0.8	0.9	0.9	0.6	0.6	0.8	0.5	0.5	-0.1	0.3	0.8	0.7
Lung cancer (father)	0.3	0.3	0.6	0.5	0.5	0.7	-0.1	0.7	0.6	0.5	0.7	0.7	0.8	0.7	0.7	0.7	0.4	0.0	0.5	0.6	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	1.4	1.0	0.8	1.0	0.5	0.8	0.9	0.8	1.0	1.1	0.9	1.2	0.9	0.8	1.0	0.3	0.8	1.0	1.1
Exposure to tobacco smoke at home	0.3	0.4	2.0	0.5	-0.4	0.3	1.4	0.8	0.7	0.7	0.4	0.6	0.1	0.1	0.8	0.5	0.2	0.5	0.9	0.5	0.4
Birth weight	0.3	0.7	6.8	-0.1	-1.9	-0.0	-0.1	-0.1	-0.3	0.1	0.2	0.0	-0.6	-0.3	0.9	0.1	-0.1	-2.6	-0.3	-0.1	-0.1
Exposure to tobacco smoke outside home	0.3	0.4	1.0	0.5	0.0	0.6	-0.3	1.0	0.7	0.9	0.9	0.9	0.1	0.6	0.9	0.5	0.5	0.2	0.7	0.7	0.7
Migraine (self-reported)	0.3	0.4	1.4	0.3	-1.2	0.4	0.3	0.6	0.4	0.4	0.5	0.6	0.5	0.3	1.0	0.6	0.1	-1.1	0.4	0.4	0.6
Age at last live birth	0.3	0.4	2.1	0.2	1.4	0.7	0.1	-0.1	0.3	-0.3	-0.2	-0.1	1.1	0.8	-0.4	0.6	0.4	1.2	0.2	0.2	0.5
Medication: Aspirin	0.3	0.4	0.8	0.7	0.2	0.5	0.6	0.6	0.9	0.9	0.7	0.9	0.1	0.3	0.7	0.5	0.6	0.2	0.5	0.8	0.8
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.9	0.7	-0.0	0.9	0.6	0.8	0.4	0.8	0.4	0.3	0.8	0.7	0.5	1.0	0.9	0.3	0.6	0.5	0.4
Qualifications: nursing, teaching	0.3	0.5	2.0	0.4	1.1	0.4	-0.8	0.5	0.4	0.1	0.6	0.7	1.4	1.2	-0.2	0.4	0.4	1.4	0.4	0.4	0.3
Guilty feelings	0.3	0.5	4.6	-0.5	-0.9	-0.5	-2.1	-0.4	-0.5	-0.5	0.0	0.1	-0.3	-0.0	-0.3	-0.7	-0.5	-0.7	-0.6	-0.4	-0.2
High cholesterol (Self-reported)	0.3	0.5	2.0	-0.4	-1.0	-0.8	-1.0	-0.5	-0.5	-0.1	-0.0	-0.1	-1.4	-0.7	0.0	-0.9	-0.4	-1.4	-0.8	-0.4	-0.3
Medication: Paracetamol	0.3	0.5	1.7	0.4	-0.2	0.7	-0.6	0.7	0.5	0.3	0.5	1.0	1.2	1.3	0.4	0.8	0.6	0.2	0.5	0.5	1.1
Diastolic blood pressure, automated reading	0.3	0.8	8.0	0.8	2.8	0.9	-0.2	0.3	0.7	0.4	0.6	0.6	0.8	0.5	-0.4	0.3	0.3	1.4	0.0	0.5	-0.3
Cholesterol lowering medication	0.3	0.5	1.3	0.5	0.2	0.5	0.3	0.5	0.7	0.3	0.6	0.8	0.8	1.1	0.5	0.6	0.8	0.8	0.8	0.7	1.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.0	-0.7	-0.7	-0.7	-0.9	-0.6	-0.5	-0.8	-0.2	-0.4	-0.9	-0.7	-0.0	-0.8	-0.7	-1.0	-0.2	-0.4	-0.2
Depression (Nagel 2018)	0.2	0.3	2.5	-0.1	0.5	0.0	-1.6	0.0	-0.2	-0.4	0.1	0.1	1.0	0.6	-0.5	-0.0	-0.2	0.6	-0.1	-0.2	-0.3
Schizophrenia vs Biploar Disorder	0.2	0.2	1.0	-0.2	-0.7	-0.5	-0.9	-0.2	-0.2	0.0	0.2	0.2	-0.7	-0.3	0.2	-0.6	-0.2	-1.0	-0.4	-0.1	-0.0
Coronary Artery Disease (CAD)	0.2	0.2	0.9	-0.3	-0.5	-0.6	-0.5	-0.4	-0.4	-0.1	0.0	-0.1	-0.7	-0.5	-0.1	-0.8	-0.3	-1.0	-0.6	-0.3	-0.3
HDL Cholesterol	0.2	0.3	0.8	-0.2	0.9	-0.4	-0.3	-0.4	-0.2	-0.3	-0.4	-0.4	-0.5	-0.5	-0.8	-0.6	-0.4	0.8	-0.5	-0.3	-0.8
Type 2 Diabetes (T2D) (2012)	0.2	0.2	2.0	-0.0	0.9	-0.0	-0.7	0.1	0.2	-0.0	0.2	0.3	0.4	0.6	-0.5	-0.3	0.3	1.4	0.1	0.1	0.4
Blood Eosinophil Count	0.2	1.2	9.6	-1.3	-0.9	-0.8	-3.1	-0.9	-1.2	-1.1	-0.5	-0.6	0.7	0.3	-1.3	-0.9	-0.5	-0.2	-1.0	-1.0	-0.5
Heel T-Score	0.2	1.7	3.0	1.4	0.6	1.0	1.0	1.3	1.2	1.4	1.7	1.2	1.0	1.2	1.6	1.0	1.7	1.0	1.5	1.4	1.3
Hypothyroidism (self reported)	0.2	0.5	2.3	-0.7	-1.2	-0.4	-1.5	-0.4	-0.8	-0.8	-0.3	-0.4	0.7	0.3	-0.4	-0.2	-0.4	-0.7	-0.4	-0.6	-0.5
Medication for hormone replacement therapy	0.2	0.2	1.4	0.1	1.2	-0.3	-0.5	-0.1	0.2	-0.0	0.2	0.4	-0.1	-0.0	-0.4	-0.4	-0.2	0.9	-0.2	0.0	-0.0
Vitamin and mineral supplements	0.2	0.3	0.8	0.4	0.7	0.6	0.1	0.4	0.4	0.3	0.4	0.3	0.5	0.8	0.2	0.4	0.7	0.9	0.6	0.5	0.8
Diabetes (mother)	0.2	0.2	0.7	0.3	-0.6	0.5	0.3	0.5	0.2	0.3	0.3	0.3	0.9	0.4	0.6	0.7	0.1	-0.7	0.4	0.2	-0.0
Leg fat-free mass (left)	0.2	0.9	2.1	0.9	-0.9	0.6	0.1	1.3	0.9	1.2	1.3	1.4	0.9	0.8	1.3	0.7	0.6	-0.5	0.7	0.9	0.6
Fed-up feelings	0.2	0.4	0.9	0.7	0.5	0.8	-0.3	0.7	0.4	0.7	1.0	0.4	0.4	0.7	0.9	0.6	0.9	-0.2	0.8	0.7	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	3.0	-0.5	-0.4	-0.4	-1.7	-0.2	-0.5	-0.5	-0.1	-0.2	0.3	0.1	-0.6	-0.5	-0.5	0.3	-0.3	-0.4	-0.5
Age when periods started (menarche)	0.2	0.5	3.0	0.1	1.2	0.6	1.2	0.1	0.6	-0.3	-0.5	0.1	0.5	0.5	-0.2	0.7	0.0	1.7	0.7	0.3	0.8
Multivitamins +/- minerals	0.2	0.3	1.1	0.6	-0.3	0.4	1.1	0.6	0.7	0.9	0.3	0.9	-0.1	-0.1	0.6	0.5	0.2	-0.3	0.0	0.4	0.2
Medication: Levothyroxine sodium	0.2	0.3	1.3	0.1	-0.9	0.5	-0.5	0.4	-0.1	0.2	0.2	0.0	1.1	1.0	0.4	0.7	0.6	-0.6	0.2	0.1	0.4
Sitting height	0.2	1.3	4.1	0.9	1.1	0.9	1.3	1.1	1.2	1.0	0.9	1.0	1.1	1.2	0.7	0.9	1.1	2.0	1.3	1.1	1.1
Chronic bronchitis/emphysema (father)	0.2	0.3	1.6	0.1	1.2	-0.1	0.2	0.2	0.3	0.3	-0.0	0.1	-0.8	-0.6	-0.4	-0.4	-0.3	1.1	-0.1	0.1	-0.3
High blood pressure (mother)	0.2	0.2	1.1	-0.1	0.6	0.0	-1.0	-0.4	-0.0	-0.7	-0.1	0.4	0.7	0.6	-0.6	0.0	-0.3	0.3	-0.3	-0.1	0.3
Had menopause	0.2	0.2	0.5	-0.4	0.5	-0.4	-0.5	-0.6	-0.3	-0.7	-0.4	-0.2	0.2	-0.1	-0.7	-0.4	-0.5	0.4	-0.4	-0.4	-0.2
Mouth/teeth dental problems	0.2	0.3	1.0	0.5	0.3	0.6	1.0	0.5	0.3	0.3	0.3	0.1	0.9	0.6	0.5	0.8	0.5	0.6	0.8	0.4	0.1
Illnesses of siblings	0.2	0.2	0.7	-0.4	0.1	-0.5	-0.5	-0.4	-0.5	-0.4	-0.5	-0.4	-0.2	-0.4	-0.9	-0.5	-0.5	0.4	-0.4	-0.6	-0.8
Neuroticism score	0.2	0.4	4.0	-0.2	-0.5	-0.3	-2.0	-0.2	-0.4	-0.0	0.4	0.1	-0.6	-0.1	0.1	-0.7	-0.2	-1.1	-0.6	-0.2	-0.2
Impedance of arm (right)	0.2	0.9	7.1	0.1	1.6	0.6	1.1	0.1	0.5	0.0	-0.3	-0.2	1.1	0.9	-0.7	0.6	0.8	2.7	0.6	0.3	0.5
Alcohol intake versus 10 years previously	0.2	0.3	1.4	-0.0	-0.8	-0.3	-0.7	0.1	-0.4	0.5	0.4	-0.2	-0.9	-0.6	0.3	-0.6	0.0	-1.2	-0.2	-0.1	-0.3
Father’s age at death	0.2	0.2	1.8	0.5	1.4	0.6	0.6	0.2	0.5	0.4	0.1	0.3	-0.0	-0.0	-0.1	0.3	0.3	0.8	0.2	0.4	0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	-0.6	-0.8	-0.2	-1.0	-0.4	-0.6	-0.5	-0.5	-0.7	-0.1	-0.4	-0.6	-0.3	-0.4	-0.9	-0.6	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.8	0.6	0.6	0.8	0.5	0.5	0.7	0.4	0.6	0.7	0.6	1.1	0.6	0.7	0.9	0.5	0.8	0.7	1.3
Medication: Lansoprazole	0.2	0.2	2.0	0.0	-0.8	0.1	-1.4	0.3	0.0	0.0	0.4	0.6	0.9	0.5	0.1	0.1	-0.1	-0.1	0.1	0.1	0.2
Birth weight of first child	0.2	0.3	1.8	0.5	1.4	0.5	0.2	0.2	0.5	0.4	0.5	0.4	0.5	0.8	0.1	0.3	0.7	0.6	0.1	0.4	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.7	0.5	0.8	0.8	0.9	0.4	0.5	0.5	0.2	0.2	0.8	0.8	0.2	0.8	0.8	0.8	0.5	0.5	0.5
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	0.6	0.3	0.4	0.5	0.6	0.5	0.7	0.4	0.6	-0.5	-0.3	0.6	0.2	0.1	-0.2	0.2	0.4	-0.1
Medication: Omeprazole	0.2	0.2	1.3	0.1	-0.7	-0.1	-1.1	0.0	-0.0	0.2	0.6	0.5	-0.2	0.4	0.5	-0.2	0.3	-1.0	-0.1	0.2	0.6
Arm predicted mass (right)	0.2	0.8	2.2	0.8	-1.3	0.4	-0.1	1.2	0.5	1.1	1.3	1.2	0.4	0.6	1.5	0.5	0.4	-1.1	0.7	0.8	0.6
Alcohol intake frequency.	0.2	0.4	0.9	0.5	0.3	0.8	-0.5	0.5	0.5	0.5	0.6	0.7	0.9	0.9	0.5	0.7	0.6	-0.3	0.2	0.5	0.8
Number of full sisters	0.2	0.3	1.2	-0.4	0.7	-0.1	-1.1	-0.4	0.1	-0.8	-0.5	0.3	0.3	0.2	-0.8	-0.1	-0.7	0.8	-0.4	-0.3	0.2
Overall health rating	0.2	0.5	3.8	-0.2	-1.0	-0.0	-1.9	-0.0	-0.3	-0.1	0.2	0.4	-0.1	0.0	0.1	-0.2	-0.5	-1.7	-0.7	-0.2	-0.2
Had major operations	0.2	0.2	0.8	-0.7	-0.7	-0.4	0.0	-0.2	-0.4	-0.3	-0.9	-0.7	-0.4	-0.3	-0.7	-0.3	-0.3	0.5	-0.1	-0.5	0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.1	-0.1	0.7	-0.4	-0.0	-0.4	-0.4	0.0	-0.2	-0.6	-1.0	-0.8	-0.4	-0.7	-0.2	-0.3	-0.6	-0.3	-0.7
Supplements: Vitamin C	0.2	0.2	1.5	-0.1	-0.5	-0.1	-0.7	-0.2	-0.5	-0.4	0.2	-0.2	0.2	0.2	0.4	-0.0	-0.0	-1.2	-0.1	-0.2	-0.4
Illnesses of siblings: Diabetes	0.2	0.3	1.1	-0.5	-1.1	-0.6	-0.8	-0.3	-0.7	-0.4	-0.2	-0.7	-0.1	-0.2	-0.2	-0.5	-0.4	-0.8	-0.5	-0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.9	0.4	-0.9	0.1	0.5	0.6	0.5	0.6	0.9	0.8	0.5	0.8	0.9	0.3	0.7	-0.2	0.5	0.6	0.5
Long-standing illness, disability or infirmity	0.2	0.4	2.1	-0.7	-1.5	-0.6	-1.5	-0.4	-0.4	-0.6	-0.1	0.1	-0.1	0.1	-0.2	-0.6	-0.4	-0.4	-0.4	-0.4	0.1
Friendships satisfaction	0.2	0.2	1.2	0.1	0.8	0.2	0.0	0.0	0.3	-0.2	-0.0	0.4	1.0	0.5	-0.4	0.3	-0.1	1.1	0.1	0.1	0.0
Back pain experienced in last month	0.2	0.3	1.3	-0.4	-1.1	-0.5	-0.5	-0.3	-0.3	-0.4	-0.2	-0.0	-0.5	-0.5	0.1	-0.4	-0.6	-1.2	-0.4	-0.3	0.0
Medication: Aspirin	0.2	0.2	0.5	0.4	-0.5	0.3	0.5	0.4	0.6	0.7	0.5	0.6	-0.1	-0.1	0.7	0.2	0.4	-0.2	0.2	0.5	0.5
Miserableness	0.2	0.3	1.1	-0.3	-1.0	-0.5	-0.9	-0.2	-0.6	-0.2	0.1	-0.3	-0.5	-0.5	0.1	-0.5	-0.3	-1.0	-0.2	-0.3	-0.5
Wears glasses or contact lenses	0.2	0.3	0.8	-0.4	0.6	0.0	-0.2	-0.3	-0.4	-0.6	-0.7	-0.7	0.6	0.0	-0.9	0.2	-0.3	0.9	-0.2	-0.4	-0.5
Ever taken oral contraceptive pill	0.2	0.2	1.8	0.2	0.6	0.1	0.7	0.2	0.6	0.3	0.1	0.6	-0.1	0.0	-0.0	0.1	0.2	1.3	0.3	0.4	0.3
Commuting to job workplace: Public transport	0.2	0.2	1.5	0.2	0.7	0.6	0.8	0.3	0.4	0.0	-0.3	0.1	0.5	0.3	-0.0	0.7	-0.0	1.2	0.4	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.3	0.3	0.6	0.7	0.2	0.3	0.4	0.3	0.0	0.1	1.1	0.6	-0.1	0.8	0.4	0.4	0.1	0.3	-0.1
Basal metabolic rate	0.2	1.1	2.5	1.1	-1.0	0.6	0.1	1.5	0.9	1.4	1.6	1.6	0.9	0.9	1.6	0.8	0.7	-0.6	0.9	1.0	0.7
Arm fat-free mass (left)	0.2	0.8	2.1	0.9	-1.2	0.3	-0.0	1.2	0.6	1.2	1.4	1.3	0.4	0.5	1.4	0.4	0.5	-1.0	0.6	0.8	0.6
Risk taking	0.2	0.2	0.9	0.5	0.2	0.3	0.9	0.5	0.6	0.3	0.3	0.9	-0.0	0.2	0.5	0.5	0.0	0.3	0.6	0.4	0.6
Unable to work because of sickness or disability	0.2	0.3	1.9	-0.1	-1.1	-0.2	-1.4	0.2	-0.0	0.1	0.5	0.5	-0.3	0.1	0.5	-0.2	-0.1	-0.8	-0.0	0.1	0.4
Commuting to job workplace: Cycle	0.2	0.2	1.0	0.3	-0.1	0.1	0.6	0.3	0.5	0.3	0.5	0.6	0.0	0.3	0.7	0.2	0.3	0.3	0.6	0.5	1.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.1	0.0	-1.1	-0.1	-0.9	0.1	-0.0	0.3	0.5	0.4	-0.1	0.2	0.5	-0.1	0.3	-1.0	-0.1	0.1	0.5
Heart disease (siblings)	0.2	0.3	1.2	0.3	-0.0	0.3	0.3	0.4	0.6	0.6	0.5	0.6	-0.4	0.3	0.7	0.1	0.5	0.1	0.4	0.6	1.1
Alcohol drinker status: Previous	0.2	0.2	1.3	-0.3	-0.5	-0.2	-1.1	-0.4	-0.0	-0.6	-0.1	0.3	0.6	0.4	-0.3	-0.2	-0.2	0.2	-0.3	-0.2	0.6
Arm predicted mass (left)	0.2	1.2	3.0	1.1	-1.0	0.5	0.0	1.5	0.8	1.4	1.7	1.5	0.7	0.8	1.7	0.6	0.7	-0.9	0.9	1.0	0.7
Depressed Affect (Nagel 2018)	0.1	0.2	2.4	-0.1	0.2	-0.1	-1.6	-0.1	-0.6	-0.0	0.3	-0.3	-0.2	-0.0	-0.1	-0.4	0.1	-0.7	-0.3	-0.2	-0.5
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.2	-0.6	0.5	-0.5	0.4	-0.8	-0.0	-0.6	-0.9	-0.3	-1.1	-0.4	-0.6	-0.6	-0.6	0.6	-0.5	-0.3	0.3
Breast Cancer	0.1	0.2	0.7	0.2	-0.6	0.1	0.0	0.4	0.2	0.5	0.5	0.4	-0.6	-0.1	0.8	0.1	0.1	-0.7	0.3	0.3	0.5
Age at First Birth	0.1	0.1	0.5	-0.2	-0.7	0.2	0.1	0.1	-0.3	0.1	-0.4	-0.6	0.2	0.1	-0.1	0.3	0.4	0.1	0.2	-0.2	0.1
Triglycerides	0.1	0.2	0.4	-0.5	-0.5	-0.3	-0.5	-0.5	-0.5	-0.5	-0.4	-0.4	-0.4	-0.3	-0.3	-0.3	-0.4	-0.6	-0.4	-0.4	-0.2
Blood Red Count	0.1	0.9	1.7	0.9	0.9	1.0	1.0	1.0	0.8	1.1	0.7	0.5	0.7	0.8	0.7	0.9	1.2	1.3	1.0	0.9	0.9
Blood White Count	0.1	0.5	2.0	0.2	-0.9	0.0	-1.4	0.4	0.2	0.6	0.9	0.9	-0.4	0.3	0.8	-0.3	0.4	-1.1	0.1	0.4	1.0
Lung FEV1/FVC ratio	0.1	0.4	2.8	-0.2	-1.3	-0.6	-1.2	0.1	-0.4	-0.2	0.6	0.2	-0.2	-0.0	0.6	-0.5	-0.4	-1.7	-0.0	-0.1	0.2
Lung FVC	0.1	0.3	3.2	0.5	-0.1	0.5	0.3	0.1	-0.1	0.5	0.3	0.0	-0.6	-0.3	0.5	0.1	0.3	-1.8	-0.2	0.2	0.1
Hand grip strength (left)	0.1	0.3	1.7	-0.2	0.9	-0.2	-0.1	-0.3	-0.2	-0.2	-0.6	-0.5	0.0	-0.3	-1.1	-0.3	-0.2	1.3	-0.4	-0.4	-0.6
Medication: Metformin	0.1	0.1	0.5	-0.3	-0.3	-0.1	-0.7	-0.2	-0.2	-0.2	-0.2	-0.2	-0.0	0.0	-0.3	-0.2	-0.1	-0.4	-0.4	-0.2	0.1
Severe depression (siblings)	0.1	0.2	1.2	-0.2	-0.1	-0.0	0.2	0.2	0.1	-0.1	0.0	-0.2	0.8	0.5	-0.1	0.2	0.2	1.1	0.5	0.1	0.2
Pack years adult smoking proportion	0.1	0.2	1.3	-0.1	-0.4	-0.2	-1.1	-0.2	-0.3	0.1	0.3	-0.0	-0.2	-0.1	-0.1	-0.5	-0.1	-0.8	-0.6	-0.1	-0.5
Impedance of leg (right)	0.1	0.6	3.7	0.4	1.8	0.6	0.8	0.2	0.6	0.3	0.0	0.1	0.2	0.4	-0.2	0.4	0.6	1.9	0.6	0.5	0.6
Hand grip strength (right)	0.1	0.1	0.6	-0.2	0.5	-0.3	0.1	-0.3	-0.0	-0.1	-0.3	-0.2	-0.4	-0.5	-0.6	-0.4	-0.3	0.8	-0.3	-0.2	-0.4
Impedance of leg (left)	0.1	0.6	3.8	0.3	1.8	0.7	0.7	0.2	0.5	0.2	-0.1	-0.1	0.4	0.5	-0.3	0.4	0.6	1.9	0.6	0.4	0.6
Leg predicted mass (left)	0.1	0.7	1.8	0.8	-1.1	0.4	-0.0	1.2	0.7	1.1	1.2	1.3	0.8	0.7	1.2	0.6	0.5	-0.6	0.5	0.8	0.5
Hearing difficulty/problems with background noise	0.1	0.2	0.5	-0.4	0.1	0.0	0.0	-0.1	-0.4	-0.3	-0.7	-0.6	0.5	-0.1	-0.6	0.2	-0.4	0.3	-0.2	-0.5	-0.7
Forced vital capacity (FVC)	0.1	0.4	1.0	0.6	0.7	0.8	0.7	0.4	0.6	0.3	0.4	0.5	0.6	0.9	0.5	0.6	0.8	0.5	0.7	0.6	1.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.9	0.1	0.3	-0.0	-0.9	-0.1	0.1	0.2	0.3	0.2	0.1	0.0	-0.1	-0.3	0.1	0.3	-0.3	0.1	0.1
Qualifications: None of the above	0.1	0.1	0.9	0.4	-0.6	0.1	-0.1	0.2	0.1	0.4	0.5	0.2	-0.0	-0.2	0.6	0.0	0.3	-1.0	0.1	0.3	0.2
Medication: Ramipril	0.1	0.1	0.5	0.1	-0.1	-0.1	-0.1	0.2	0.3	0.1	0.3	0.6	-0.4	0.0	0.3	-0.1	-0.0	0.2	0.3	0.3	0.7
Medication: Simvastatin	0.1	0.1	0.5	0.2	0.7	0.3	-0.1	0.1	0.3	-0.1	0.2	0.3	-0.3	0.2	0.2	0.2	0.0	0.5	0.4	0.3	0.3
Trunk fat-free mass	0.1	0.6	1.8	0.7	-1.2	0.1	0.1	1.1	0.5	1.0	1.3	1.1	0.3	0.4	1.4	0.3	0.4	-0.8	0.6	0.7	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	-0.3	0.3	0.0	0.0	-0.3	-0.3	-0.6	-0.6	-0.5	0.5	0.2	-0.6	0.1	-0.1	0.5	0.0	-0.3	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	0.2	0.1	-0.2	0.4	0.1	0.3	0.3	0.5	0.4	-0.5	-0.2	0.3	-0.3	0.2	0.0	0.2	0.3	0.3
Impedance of arm (left)	0.1	0.6	4.6	0.0	1.3	0.6	1.0	-0.0	0.5	-0.1	-0.4	-0.1	0.9	0.8	-0.5	0.7	0.6	2.2	0.5	0.3	0.5
Trunk predicted mass	0.1	0.5	1.5	0.6	-1.2	0.0	0.0	1.0	0.4	0.9	1.2	1.0	0.2	0.3	1.2	0.2	0.3	-0.8	0.5	0.6	0.3
Standing height	0.1	0.8	2.6	0.5	0.1	0.5	1.6	0.9	0.9	0.7	0.6	0.7	0.9	1.0	0.6	0.7	0.9	1.6	1.1	0.8	0.9
Tense / ‘highly strung’	0.1	0.2	1.6	0.1	1.3	0.2	-0.8	-0.1	0.2	-0.2	0.1	0.2	-0.3	0.2	-0.2	-0.2	-0.1	0.6	-0.0	0.2	0.3
Pulse wave reflection index	0.1	0.1	1.2	0.0	0.3	0.1	-0.2	0.2	0.1	0.2	0.2	0.0	-0.2	0.3	-0.1	-0.1	0.5	1.1	0.4	0.2	0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.8	0.0	-0.3	0.4	-1.1	0.2	-0.1	-0.1	0.3	0.1	1.4	1.0	0.1	0.4	0.3	-0.2	0.1	0.0	0.1
High blood pressure (siblings)	0.1	0.2	1.1	-0.1	1.0	0.4	0.2	-0.4	0.0	-0.6	-0.7	-0.3	0.3	-0.0	-0.4	0.4	-0.5	0.1	-0.3	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.2	0.6	0.4	0.8	0.5	0.5	0.2	0.4	0.2	0.3	0.3	0.5	0.7	0.2	0.4	0.6	0.3	0.3	0.4	0.4
Arm fat-free mass (right)	0.1	0.6	2.5	0.6	-1.6	0.1	-0.3	1.0	0.4	0.9	1.1	1.1	0.2	0.3	1.3	0.3	0.1	-1.4	0.4	0.5	0.3
Comparative body size at age 10	0.1	0.3	0.8	0.4	-0.6	0.4	-0.0	0.7	0.4	0.8	0.7	0.7	0.4	0.8	0.7	0.4	0.8	0.1	0.5	0.5	0.9
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	0.3	-0.4	0.4	-0.4	0.4	0.2	0.5	0.6	0.4	0.2	0.5	0.6	0.3	0.5	-0.7	0.1	0.3	0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	0.2	0.3	0.3	-0.3	0.1	0.3	0.4	0.4	0.3	-0.4	-0.1	0.3	-0.1	0.3	-0.2	-0.1	0.3	0.2
Neck or shoulder pain in last month	0.1	0.1	0.4	-0.3	0.2	0.2	-0.7	-0.0	-0.0	-0.3	-0.4	-0.1	0.3	0.1	-0.4	0.2	-0.4	-0.0	-0.1	-0.2	0.0
Medication: Blood pressure	0.1	0.2	0.6	0.3	0.0	0.2	0.2	0.3	0.5	0.1	0.4	0.7	0.4	0.3	0.5	0.3	0.0	0.3	0.5	0.4	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.8	-0.3	0.4	0.2	-0.3	-0.1	-0.1	-0.5	-0.6	-0.4	0.5	0.5	-0.6	0.3	-0.1	0.9	-0.0	-0.2	0.0
Chest pain or discomfort	0.1	0.1	0.6	0.1	-0.5	0.2	-0.8	0.4	-0.0	0.1	0.5	0.3	0.3	0.5	0.3	0.2	0.2	-0.4	0.3	0.2	0.4
Family relationship satisfaction	0.1	0.2	1.2	-0.2	0.4	0.0	-0.3	-0.2	0.1	-0.4	-0.3	0.0	0.7	0.2	-0.6	0.0	-0.2	1.1	-0.0	-0.1	-0.2
Whole body fat-free mass	0.1	0.8	2.0	0.8	-1.2	0.4	0.1	1.2	0.7	1.1	1.3	1.3	0.6	0.6	1.4	0.5	0.5	-0.7	0.7	0.8	0.6
Leg fat-free mass (right)	0.1	0.5	1.2	0.6	-1.0	0.4	-0.1	1.0	0.6	0.9	1.0	1.1	0.8	0.7	1.0	0.6	0.4	-0.6	0.4	0.6	0.4
Mood swings	0.1	0.1	0.7	0.2	-0.4	0.2	-0.7	0.2	-0.1	0.3	0.5	-0.0	-0.4	-0.0	0.6	0.0	0.3	-0.8	0.1	0.2	0.3
Diabetes diagnosed by doctor	0.1	0.2	0.6	0.4	0.2	0.4	-0.3	0.6	0.6	0.7	0.8	0.7	0.4	0.5	0.5	0.2	0.4	-0.0	0.1	0.6	0.5
Mineral and other dietary supplements	0.1	0.2	1.0	0.3	1.0	0.6	0.3	0.2	0.3	0.3	0.1	0.0	0.3	0.4	0.0	0.4	0.5	0.7	0.4	0.3	0.6
Illnesses of father: None of the above (group 1)	0.1	0.1	1.1	0.2	0.3	0.3	0.0	0.1	0.1	-0.0	0.1	0.1	1.0	0.6	0.0	0.5	0.4	0.5	0.3	0.1	0.4
Whole body water mass	0.1	0.6	1.6	0.7	-1.2	0.2	0.0	1.1	0.5	1.0	1.2	1.1	0.5	0.5	1.3	0.4	0.4	-0.8	0.6	0.7	0.4
Leg predicted mass (right)	0.1	0.6	1.2	0.6	-1.0	0.4	-0.1	1.0	0.6	0.9	1.0	1.1	0.8	0.7	1.0	0.6	0.4	-0.6	0.5	0.6	0.4
Average weekly champagne plus white wine intake	0.1	0.2	0.6	-0.2	0.7	-0.0	0.0	-0.6	-0.4	-0.3	-0.6	-0.8	-0.4	-0.4	-0.5	-0.2	-0.2	-0.4	-0.7	-0.4	-0.3
Myopia	0.1	0.2	0.8	0.1	0.9	0.6	0.4	0.0	0.2	-0.2	-0.2	-0.3	0.5	0.4	-0.1	0.5	0.2	0.6	0.3	0.2	0.0
Pain experienced in last month	0.1	0.2	0.9	0.2	0.7	0.2	0.3	0.0	0.2	-0.2	0.2	0.1	0.9	0.6	-0.1	0.3	0.3	0.9	0.3	0.2	0.1
Basal cell carcinoma (self-reported)	0.1	0.2	1.1	-0.4	-0.2	-0.4	0.5	-0.3	-0.1	-0.6	-0.5	-0.4	0.3	-0.0	-0.5	-0.1	-0.3	1.0	0.2	-0.2	-0.3
Pack years of smoking	0.1	0.2	1.3	-0.1	-0.2	-0.2	-1.1	-0.2	-0.3	0.0	0.2	-0.1	-0.2	-0.1	-0.1	-0.4	-0.1	-0.8	-0.7	-0.2	-0.5
Impedance of whole body	0.1	0.7	4.8	0.2	1.7	0.8	0.9	0.1	0.5	-0.0	-0.3	-0.1	0.9	0.9	-0.5	0.7	0.8	2.2	0.6	0.4	0.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.1	0.6	0.1	0.8	0.2	0.2	0.0	0.1	0.2	-0.1	-0.0	0.2	0.0	-0.3	0.1	0.3	0.3	-0.2	0.0	-0.0
Height	0.0	0.6	4.7	-0.1	1.0	0.4	1.2	-0.0	0.4	-0.5	-0.5	-0.1	1.1	0.8	-0.5	0.6	0.2	2.2	0.6	0.1	0.3
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.3	0.1	0.5	0.2	-0.5	0.2	0.3	0.2	0.2	0.4	-0.0	0.1	-0.1	-0.0	-0.0	0.3	-0.1	0.2	0.3
Hair Pigment	0.0	0.8	3.1	-0.4	0.7	-1.0	-1.8	-0.8	-0.6	-0.9	0.1	0.2	-0.7	-0.8	-0.8	-1.2	-1.1	-0.1	-0.9	-0.6	-1.5
Tanning	0.0	0.6	1.1	-0.6	-0.1	-0.7	0.1	-1.0	-0.7	-1.0	-0.9	-1.0	-0.8	-1.1	-0.7	-0.6	-0.9	-0.5	-0.7	-0.7	-1.1
Average weekly spirits intake	0.0	0.0	0.4	-0.0	0.4	-0.1	0.0	-0.1	0.1	0.1	0.0	0.3	-0.6	-0.1	-0.1	-0.2	-0.0	0.0	-0.3	0.0	0.0
Relative age of first facial hair	0.0	0.1	0.2	0.2	0.4	0.4	0.0	0.1	-0.0	0.0	0.0	-0.1	0.5	0.3	0.1	0.5	0.3	-0.0	0.2	0.1	0.1
Relative age voice broke	0.0	0.0	0.2	-0.1	-0.2	0.1	-0.5	-0.1	-0.1	-0.1	-0.1	0.0	-0.1	0.1	0.0	0.0	0.1	-0.2	-0.1	-0.0	0.2
Happiness	0.0	0.1	0.3	0.1	0.5	0.1	-0.5	-0.2	-0.2	-0.1	0.1	-0.2	0.2	0.3	-0.2	-0.2	0.4	0.2	-0.1	-0.0	0.1
Comparative height size at age 10	0.0	0.1	1.1	0.0	0.3	0.0	0.5	0.1	0.3	0.1	-0.1	0.1	0.0	0.1	-0.2	-0.1	0.1	1.1	0.1	0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.5	-0.1	0.3	0.1	-0.5	-0.4	-0.4	-0.7	-0.3	-0.2	-0.0	0.2	-0.1	0.0	-0.3	-0.6	-0.1	-0.2	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.2	0.0	-0.5	0.1	-0.3	0.1	-0.2	0.0	0.1	-0.1	0.3	0.2	0.1	0.2	0.1	-0.4	0.0	-0.0	-0.1

Hub : Genes

C19orf33

Models

Trait associations