TWAS hub - C1orf190

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0779	0.0283	3.2e-10	0.036	0.048	0.047	NA	0.039	5.6e-08	3.4e-10	6.8e-10	NA	1.4e-08
2	TCGA	Colon Adenocarcinoma	0.1100	0.0570	9.1e-04	0.017	0.040	0.047	NA	0.034	3.6e-02	2.3e-03	1.1e-03	NA	4.7e-03
3	TCGA	Kidney Renal Clear Cell Carcinoma	0.1062	0.0666	7.4e-06	0.053	0.038	0.034	NA	0.046	1.2e-06	4.0e-05	9.7e-05	NA	5.4e-06
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0720	0.0390	1.1e-04	0.034	0.064	0.053	NA	0.044	5.0e-03	1.5e-04	5.7e-04	NA	1.5e-03
5	TCGA	Brain Lower Grade Glioma	0.0580	0.0294	1.2e-04	0.029	0.031	0.016	NA	0.016	2.8e-04	1.7e-04	5.6e-03	NA	4.9e-03
6	TCGA	Liver Hepatocellular Carcinoma	0.5440	0.1010	1.6e-08	0.145	0.195	0.177	NA	0.193	2.4e-07	1.5e-09	9.5e-09	NA	1.9e-09
7	TCGA	Lung Adenocarcinoma	0.0876	0.0336	4.3e-11	0.094	0.089	0.073	NA	0.084	4.2e-11	1.3e-10	6.0e-09	NA	5.0e-10
8	TCGA	Pancreatic Adenocarcinoma	0.1870	0.0780	2.1e-04	0.085	0.084	0.044	NA	0.052	2.0e-04	2.2e-04	6.2e-03	NA	3.2e-03
9	TCGA	Prostate Adenocarcinoma	0.2756	0.0766	1.4e-06	0.095	0.076	0.084	NA	0.096	3.7e-10	2.2e-08	4.2e-09	NA	3.0e-10
10	TCGA	Soft Tissue Sarcoma	0.0600	0.0290	4.0e-05	0.100	0.086	0.083	NA	0.100	1.6e-06	8.0e-06	1.2e-05	NA	1.6e-06
11	TCGA	Thyroid Carcinoma	0.0630	0.0390	6.4e-04	0.029	0.025	0.012	NA	0.016	7.4e-04	1.6e-03	2.0e-02	NA	9.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Number of full sisters	5.1	6.2	12.1	-2.5	-2.2	-1.9	-2.9	-3.2	-0.4	-2.8	-3.5	0.2	-3.1	-2.2
Guilty feelings	4.9	7.4	11.9	2.3	2.0	3.2	3.4	2.5	-1.0	2.8	2.9	-2.2	3.5	3.3
Exposure to tobacco smoke at home	4.4	5.0	10.4	-1.0	-2.2	-3.2	-2.9	-1.7	1.4	-2.6	-1.4	1.3	-2.8	-2.5
Financial situation satisfaction	4.3	5.3	8.6	-2.9	-2.5	-1.0	-1.7	-2.6	-1.8	-2.7	-2.6	-2.1	-2.3	-2.4
Age started oral contraceptive pill	4.2	5.2	8.8	2.8	1.7	2.1	2.6	2.7	0.1	2.2	2.8	-0.0	3.0	2.6
Pain all over the body in last month	4.1	4.4	9.1	2.4	2.1	0.1	-0.0	3.0	3.0	2.1	2.3	2.8	1.2	0.7
Ever had bowel cancer screening	4.1	4.8	8.9	1.2	2.5	2.4	2.6	2.9	0.1	2.3	2.0	-1.2	3.0	2.2
Ulcerative Colitis (UC)	3.7	6.9	13.6	2.4	3.7	2.7	3.2	2.5	0.0	3.3	2.6	-0.0	2.8	2.6
Qualifications: nursing, teaching	3.7	5.7	11.2	2.9	2.6	1.9	1.7	2.7	1.5	3.2	3.3	1.6	2.2	1.8
Leg pain on walking	3.6	4.5	7.2	-2.3	-2.5	-1.7	-2.1	-2.4	-1.2	-2.7	-2.1	-1.2	-2.3	-2.2
Had menopause	3.5	4.4	10.5	1.9	3.2	2.5	2.2	1.9	0.5	2.7	1.9	1.4	1.8	1.8
Reason for reducing amount of alcohol drunk: Health precaution	3.4	4.0	7.6	1.3	1.4	2.1	2.6	2.1	-1.1	1.9	1.6	-1.9	2.8	2.5
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	7.6	-2.5	-1.9	-1.3	-1.7	-1.9	-0.4	-2.2	-2.8	-0.7	-1.9	-1.7
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	8.0	2.0	1.9	1.3	1.0	2.8	1.2	2.3	1.8	0.7	2.1	2.1
Smoking Status	3.1	7.4	14.8	-1.7	-2.9	-3.6	-3.9	-1.7	2.1	-2.5	-2.2	2.6	-3.1	-2.8
Average weekly fortified wine intake	2.8	3.3	6.7	1.7	1.0	1.9	1.5	2.6	0.0	2.3	2.4	-0.8	2.3	1.8
Ever smoked	2.8	4.9	9.5	-1.7	-1.3	-3.1	-3.0	-0.8	2.2	-1.8	-1.6	2.2	-2.4	-2.9
Past tobacco smoking	2.7	5.0	13.1	0.6	1.1	3.6	2.9	0.4	-3.0	1.4	1.1	-3.1	2.1	2.3
Breast Cancer	2.6	6.2	13.5	2.8	3.7	2.6	3.0	1.6	0.3	3.2	2.5	0.2	2.2	2.8
Hearing difficulty/problems: Yes	2.6	4.0	9.9	0.7	1.3	3.1	3.0	1.5	-1.5	1.6	1.4	-2.0	2.4	2.1
Other serious medical condition/disability diagnosed by doctor	2.6	3.4	9.8	1.7	2.0	0.6	0.4	3.1	2.2	2.1	2.1	1.8	1.5	0.8
Current tobacco smoking	2.5	4.0	7.8	-2.2	-2.2	-1.5	-2.8	-1.5	0.1	-2.0	-2.1	0.7	-2.4	-2.6
Father’s age at death	2.5	3.3	7.8	1.0	1.2	2.8	2.4	1.3	-1.2	1.8	2.1	-1.1	2.3	1.7
Blood Red Count	2.3	22.1	49.6	-0.1	0.2	6.9	7.0	2.0	-6.3	2.2	1.3	-6.5	5.7	4.6
Diabetes diagnosed by doctor	2.3	3.8	8.3	-2.9	-1.9	-1.6	-2.3	-1.0	0.2	-2.3	-2.1	-0.3	-1.8	-2.7
Smoking status: Current	2.3	3.7	8.2	-1.8	-2.2	-1.8	-2.9	-1.2	0.4	-2.0	-1.8	0.9	-2.3	-2.5
Risk taking	2.3	3.4	10.4	2.2	-0.2	2.0	1.5	1.8	0.0	2.0	3.2	-0.2	2.1	2.1
Townsend deprivation index at recruitment	2.2	3.1	6.5	-1.8	-0.5	-2.0	-2.1	-1.2	0.2	-2.1	-2.2	-0.4	-2.2	-2.5
Pulse rate	2.0	3.4	12.6	-1.8	-0.9	1.6	0.9	-1.8	-3.6	-0.8	-1.9	-3.2	-0.3	-0.3
Schizophrenia vs Biploar Disorder	1.9	2.5	8.1	-1.3	-0.6	2.2	1.6	-0.5	-2.8	-0.4	-0.6	-2.8	0.9	0.6
Financial difficulties in last 2 years	1.9	2.6	4.6	-2.1	-1.0	-1.4	-1.9	-1.7	0.2	-1.6	-2.1	0.0	-2.1	-1.9
Time employed in main current job	1.9	2.2	4.3	-1.9	-1.5	-0.9	-1.2	-1.5	-0.9	-1.7	-2.1	-1.0	-1.5	-1.5
Loud music exposure frequency	1.9	2.0	5.7	2.2	1.5	0.3	0.7	1.5	1.2	1.7	2.4	0.9	1.0	0.7
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	6.9	1.5	1.5	1.0	0.8	2.6	1.8	2.1	2.0	1.7	1.6	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	5.1	1.6	1.4	0.1	-0.1	1.9	2.1	1.4	0.7	2.3	0.6	0.5
Fractured/broken bones in last 5 years	1.8	2.3	7.5	2.4	-0.7	-1.1	-0.5	1.4	2.2	0.7	1.5	2.7	0.3	0.6
Hand grip strength (right)	1.7	4.6	8.6	2.6	2.0	2.0	2.5	1.7	0.3	2.5	2.9	-0.1	2.5	2.4
Hair/balding pattern: Pattern 2	1.7	2.1	6.1	1.1	0.4	1.8	1.4	1.3	-0.3	1.6	1.5	-0.3	2.0	2.5
Type 2 Diabetes (T2D) (2018)	1.6	3.1	7.7	-2.8	-1.9	-1.5	-2.1	-0.7	0.0	-1.9	-1.9	-0.6	-1.5	-2.3
Stomach or abdominal pain in last month	1.6	2.0	4.4	0.8	0.9	2.0	1.4	2.1	0.1	1.6	1.4	-0.1	1.9	1.5
Number of incorrect matches in round	1.6	2.6	10.5	-0.0	-0.5	1.9	1.7	0.5	-2.3	0.3	0.3	-3.2	1.5	1.9
Illnesses of mother	1.6	1.9	3.4	1.3	1.7	1.6	1.8	1.2	-0.6	1.5	1.3	-0.9	1.4	1.5
Crohns Disease (2012)	1.5	2.4	9.4	-1.6	-0.9	1.9	1.0	-0.4	-2.7	-0.5	-1.1	-3.1	0.5	0.6
LDL Cholesterol	1.5	2.4	4.9	-1.9	-2.2	-0.8	-0.7	-2.2	-1.3	-2.0	-1.5	-1.1	-1.3	-0.9
Hand grip strength (left)	1.5	3.9	8.3	2.1	1.6	1.9	2.2	2.0	0.4	2.3	2.9	-0.3	2.4	2.0
Maternal smoking around birth	1.5	2.1	5.9	-0.9	-0.6	-1.6	-2.4	-0.9	0.8	-0.9	-1.7	1.4	-1.9	-1.9
Chronic bronchitis/emphysema (father)	1.5	1.7	4.2	0.8	1.4	2.1	1.7	1.1	-1.1	1.4	0.7	-0.8	1.5	1.4
Mouth/teeth dental problems: Dentures	1.5	2.5	5.5	-2.3	-1.5	-1.0	-1.2	-1.4	-1.2	-1.9	-2.3	-1.6	-1.3	-1.0
Friendships satisfaction	1.5	1.8	5.1	1.4	1.1	1.1	1.9	0.7	0.2	1.6	2.3	0.0	1.5	1.2
Back pain experienced in last month	1.5	2.2	8.7	1.1	1.4	-1.5	-1.2	1.3	3.0	0.4	1.1	2.1	-0.6	-1.3
Mouth/teeth dental problems	1.4	2.1	4.5	1.4	0.0	1.6	1.7	1.7	-0.3	1.3	1.8	-0.1	2.1	1.8
Diabetes (self-reported)	1.4	2.2	5.9	-2.2	-1.4	-1.3	-1.9	-0.4	0.6	-1.6	-1.3	0.2	-1.2	-2.4
Happiness	1.4	1.7	3.0	1.0	1.0	1.7	1.5	1.0	-0.0	1.6	1.3	-0.2	1.7	1.7
Pulse wave Arterial Stiffness index	1.4	1.6	5.3	-1.5	-2.3	-0.6	-0.8	-1.2	-1.1	-1.3	-1.6	-1.5	-0.6	-0.1
High blood pressure (siblings)	1.4	2.1	3.4	-1.3	-1.9	-0.8	-1.7	-1.4	-0.9	-1.7	-1.4	-1.1	-1.7	-1.6
Pulse wave peak to peak time	1.4	1.7	5.2	1.5	2.3	0.7	0.7	1.1	1.2	1.3	1.6	1.6	0.5	0.1
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.9	-1.8	-0.9	-0.2	-0.7	-1.7	-1.1	-1.4	-2.0	-0.6	-1.4	-1.1
Hearing aid user	1.4	1.6	3.3	1.0	0.3	1.2	1.8	0.9	-0.7	0.9	1.5	-1.2	1.8	1.7
Myopia	1.4	2.1	6.2	-2.5	-1.3	-0.2	-0.9	-1.4	-1.4	-1.5	-1.9	-1.4	-1.1	-1.2
HDL Cholesterol	1.3	2.1	4.5	2.1	1.2	0.1	-0.0	1.8	2.1	1.3	1.8	1.7	0.8	1.0
Blood White Count	1.3	9.9	24.9	-4.8	-2.9	1.0	0.1	-2.0	-4.5	-2.9	-4.2	-5.0	-0.6	-1.1
Systolic blood pressure, automated reading	1.3	3.7	7.0	-2.6	-1.4	-2.2	-2.2	-1.5	0.7	-2.2	-2.1	0.0	-2.1	-2.4
Supplements: Zinc	1.3	1.4	3.2	-1.0	-1.4	-1.5	-1.8	-0.5	1.1	-1.2	-0.6	0.7	-1.1	-1.5
Asthma	1.3	2.5	7.1	2.2	0.7	-0.9	-0.7	1.6	2.7	1.1	2.0	2.3	0.4	0.8
Prospective memory result	1.3	1.6	5.1	-0.5	-1.1	-1.1	-1.0	-2.3	-0.6	-1.4	-1.5	-0.5	-1.8	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	2.7	-1.6	-1.3	-1.0	-1.3	-1.3	-0.2	-1.5	-1.6	-1.0	-1.2	-0.8
Chest pain or discomfort	1.3	1.9	4.8	0.3	-1.7	-1.9	-2.2	0.2	1.8	-0.8	-0.0	1.8	-1.2	-1.2
Supplements: Calcium	1.3	1.5	3.8	1.9	1.8	-0.6	-0.0	1.5	1.7	1.1	0.8	1.1	0.6	0.4
Irritable Bowel Disease (IBD)	1.2	2.8	7.8	1.4	2.8	1.9	2.3	1.4	-0.3	2.0	1.2	-0.6	1.7	1.5
Neuroticism (2016)	1.2	1.8	3.6	1.4	0.5	1.4	1.8	0.5	-0.8	1.0	1.6	-1.2	1.5	1.9
Rheumatoid Arthritis	1.2	1.6	4.3	-1.2	-1.0	-1.9	-2.1	-0.4	1.3	-1.0	-0.6	0.4	-1.3	-1.4
Waist circumference	1.2	4.4	9.9	-2.0	-2.0	-2.0	-3.1	-1.4	0.6	-1.9	-2.0	0.9	-2.9	-2.7
Hearing difficulty/problems with background noise	1.2	1.9	4.3	0.7	1.3	2.1	1.9	1.4	-0.5	1.5	0.9	-0.6	1.8	1.5
Tense / ‘highly strung’	1.2	2.0	5.2	0.5	-0.4	1.5	1.8	0.9	-1.6	0.6	0.9	-2.3	1.8	1.9
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.1	-0.5	-0.8	-1.6	-1.8	-0.9	0.7	-0.7	-0.8	1.0	-1.6	-1.7
Illnesses of siblings: Diabetes	1.2	1.5	3.9	-1.0	-1.7	-2.0	-1.2	-0.6	0.0	-1.7	-1.4	-0.1	-0.9	-1.0
Asthma (self-reported)	1.2	2.4	7.6	2.1	0.5	-1.1	-0.8	1.6	2.8	1.0	1.9	2.3	0.3	0.7
Number of operations (self-reported)	1.2	1.8	6.2	0.7	0.8	0.2	-0.4	2.5	2.1	1.3	1.2	1.9	0.9	0.1
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.4	0.8	1.2	1.5	1.9	0.7	-0.5	1.3	0.9	0.1	1.4	1.5
Pain experienced in last month	1.2	2.0	5.9	-1.8	-1.0	0.0	0.4	-1.7	-1.9	-1.3	-1.8	-2.4	-0.3	-0.3
Ever had hysterectomy (womb removed)	1.1	1.2	4.6	0.6	0.8	-0.3	-0.5	2.1	1.6	1.1	1.6	0.6	0.6	-0.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	3.6	-0.6	1.4	-1.7	-1.5	-0.4	1.9	-0.2	-0.7	1.0	-1.3	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	4.1	2.0	0.5	-0.6	-0.3	0.7	2.0	0.7	1.4	2.0	0.2	0.9
Qualifications: College or University degree	1.1	3.5	5.3	2.2	1.4	1.5	2.2	1.5	1.0	2.2	2.3	1.8	2.0	1.9
Pulse rate, automated reading	1.1	3.5	10.6	-1.6	0.1	2.9	1.7	-0.3	-3.3	0.5	-1.3	-3.1	1.1	0.7
Wears glasses or contact lenses	1.1	1.2	3.2	-0.6	-0.5	-1.3	-1.8	-0.5	1.2	-1.0	-0.2	0.8	-1.5	-1.7
Pain type(s) experienced in last month: Hip pain	1.1	1.3	2.6	1.2	0.3	0.8	0.8	1.5	0.6	1.5	1.3	0.8	1.5	1.6
Alzheimer’s Disease (in father)	1.0	1.1	2.4	1.5	0.1	1.5	1.1	0.3	-0.9	0.9	1.4	-0.5	1.0	1.1
Hypothyroidism (self reported)	1.0	2.3	6.1	-1.7	-0.1	-2.5	-2.2	0.8	2.0	-0.7	-0.5	0.7	-1.0	-2.2
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.8	1.1	1.3	1.7	1.2	0.6	-1.0	1.1	1.3	-0.8	0.8	1.0
Diabetes (mother)	1.0	1.3	3.0	-1.2	-1.3	-0.3	-1.2	-1.7	-0.7	-1.1	-1.5	0.1	-1.4	-0.6
Serious illness, injury or assault to yourself	1.0	1.2	5.1	0.8	0.6	0.7	0.4	2.2	1.1	1.0	1.6	0.4	1.3	0.3
Alcohol intake versus 10 years previously	1.0	1.5	3.3	-0.7	-0.9	-1.8	-1.6	-0.8	1.0	-1.2	-1.2	1.1	-1.4	-1.3
Noisy workplace	1.0	1.2	3.5	1.9	0.6	-0.2	0.6	1.0	0.6	1.2	1.8	0.0	1.0	1.5
Number of children fathered	1.0	1.1	4.5	0.7	1.3	0.7	0.6	2.1	0.9	1.2	0.9	0.6	1.1	0.2
Family relationship satisfaction	1.0	1.3	3.0	0.9	0.7	1.6	1.7	0.8	-0.2	1.2	1.6	0.2	1.3	1.1
Smoking status: Previous	1.0	1.5	5.3	0.8	-0.0	-2.2	-0.8	0.3	2.3	-0.1	0.2	2.3	-0.5	-0.3
Loneliness, isolation	1.0	1.4	2.5	0.7	1.5	1.5	1.0	1.6	0.6	1.5	0.9	0.0	1.3	1.2
Osteoporosis (self-reported)	1.0	1.2	3.0	1.7	0.6	-0.3	0.2	0.8	1.7	0.9	1.2	1.7	0.6	0.8
Eye problems/disorders: Glaucoma	1.0	1.2	3.3	1.4	0.3	-0.6	-0.4	1.2	1.8	0.7	1.3	1.8	0.4	0.1
HbA1C	0.9	1.0	4.1	-1.4	-2.0	0.0	-1.1	-0.6	-0.2	-1.0	-0.4	-0.6	-0.7	-1.2
Pack years adult smoking proportion	0.9	1.4	4.0	-1.2	-2.0	-0.4	-1.4	-1.0	-0.5	-1.4	-1.1	-0.6	-1.1	-1.0
Taking other prescription medications	0.9	1.4	3.2	1.5	0.5	0.9	0.4	1.8	0.5	1.3	1.8	0.5	1.2	1.2
Qualifications: CSEs or equivalent	0.9	1.1	2.5	-1.3	-1.4	-0.9	-1.3	-0.9	-0.4	-1.1	-1.6	-0.5	-1.0	-0.6
Medication: Simvastatin	0.9	1.3	2.5	-1.3	-1.3	-1.3	-1.6	0.1	1.2	-1.1	-0.9	0.7	-0.8	-1.3
Fluid intelligence score	0.9	1.9	10.7	0.5	0.7	-1.0	-0.7	-0.2	2.4	0.2	0.5	3.3	-0.8	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.4	1.1	1.2	1.0	0.6	1.2	0.7	1.3	1.5	0.3	0.7	0.8
Medication: Paracetamol	0.9	1.6	3.0	1.2	0.4	1.7	0.7	1.4	-0.2	1.7	1.7	0.2	1.4	1.6
Overall health rating	0.9	2.0	4.3	-1.7	-0.9	-1.4	-2.0	-0.6	0.9	-1.2	-2.1	0.6	-1.5	-1.5
Supplements: Vitamin C	0.9	1.0	3.0	1.3	-0.5	0.3	-0.1	1.5	1.0	0.8	1.7	0.9	1.0	0.6
Cholesterol lowering medication	0.9	1.3	3.1	-1.1	-0.7	-1.2	-1.8	0.4	1.3	-0.9	-0.7	0.8	-1.0	-1.8
Depression (Nagel 2018)	0.8	1.3	2.4	1.2	1.4	1.4	1.0	1.2	0.1	1.5	1.0	0.0	1.2	1.2
Intelligence (Savage-Jansen 2018)	0.8	2.4	9.2	1.8	1.6	-1.2	-0.1	0.4	2.6	0.5	1.2	3.0	-0.2	-0.5
Fasting Glucose	0.8	1.0	2.5	-0.6	-1.6	-1.4	-1.3	-0.9	0.3	-1.0	-0.6	0.9	-0.9	-0.9
Lupus	0.8	1.3	2.3	1.2	1.3	0.9	1.4	0.7	-0.4	1.5	1.2	-0.1	1.2	1.5
Ulcerative Colitis	0.8	1.2	2.4	0.4	1.4	1.5	1.6	0.6	-0.8	1.4	0.7	-0.7	1.1	1.2
Waist Hip Ratio (WHR)	0.8	3.6	8.6	-2.1	-1.9	-1.2	-1.8	-1.6	-0.9	-2.3	-2.9	-0.1	-2.2	-2.3
Neuroticism	0.8	1.9	3.6	0.9	1.4	1.6	1.9	1.2	-0.1	1.6	1.1	-1.2	1.8	1.7
Illnesses of siblings	0.8	1.2	2.0	0.6	1.2	1.3	1.2	0.8	0.5	1.3	1.0	0.7	1.3	1.4
Arm fat percentage (right)	0.8	3.3	8.8	-2.1	-1.6	-1.4	-3.0	-0.8	0.9	-1.4	-1.7	1.3	-2.3	-2.3
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.2	1.1	0.5	1.0	1.2	1.8	1.1	1.5	1.8	1.2	1.6	1.1
Glaucoma (self-reported)	0.8	1.0	1.9	1.3	0.8	0.1	0.2	1.2	1.3	1.0	1.4	1.3	0.5	0.1
Migraine (self-reported)	0.8	1.0	2.1	-0.7	-1.3	-0.8	-0.3	-1.4	-0.9	-1.5	-0.8	-0.4	-1.1	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.6	-0.9	-0.1	-1.6	-1.0	-0.3	0.4	-1.1	-1.2	-0.5	-0.8	-1.4
Long-standing illness, disability or infirmity	0.8	1.2	3.5	1.2	0.3	0.3	-0.2	1.9	1.6	1.0	1.6	1.1	0.7	0.5
Commuting to job workplace: Walk	0.8	0.9	2.3	1.5	0.3	-0.7	0.0	0.5	1.5	0.6	1.3	1.5	0.2	0.1
Breast cancer (self-reported)	0.8	1.0	2.1	-1.5	-0.4	-0.9	-0.9	-0.7	-0.4	-1.1	-1.4	-0.3	-1.1	-1.4
Diastolic blood pressure, automated reading	0.8	2.5	7.0	-2.6	-1.7	-0.7	-1.6	-1.5	-0.3	-1.5	-2.0	-1.0	-1.6	-1.5
Basal cell carcinoma (self-reported)	0.8	0.9	1.8	1.0	-0.5	1.3	1.2	0.3	-0.9	0.6	1.2	-0.7	1.0	1.4
Prostate Cancer	0.7	1.0	4.0	-2.0	-0.7	-0.3	-0.6	0.0	-0.4	-0.9	-1.7	-1.2	-0.1	-0.4
Systolic Blood Pressure	0.7	3.3	6.9	-2.0	-0.8	-2.6	-2.4	-0.9	1.6	-1.7	-2.2	0.5	-1.8	-2.0
Respiratory disease	0.7	1.6	4.7	1.7	0.2	-0.7	-0.7	1.2	2.2	0.7	1.6	2.0	-0.0	0.2
Medication for hormone replacement therapy	0.7	0.8	2.8	-1.1	-0.2	1.4	0.3	0.1	-1.3	0.3	-0.3	-1.7	0.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	4.6	-1.1	-0.7	0.1	-0.2	-0.1	-1.1	-0.9	-0.5	-2.1	-0.2	-0.6
Multivitamins +/- minerals	0.7	0.9	3.6	-0.3	-1.9	-1.2	-1.5	-0.4	0.6	-0.9	0.3	0.7	-0.7	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.5	1.1	1.2	1.6	1.1	0.8	-0.5	1.2	0.8	-0.5	1.0	1.2
Length of working week for main job	0.7	0.7	1.8	-0.8	-0.2	-1.0	-1.4	-0.0	1.1	-0.4	-0.9	0.6	-0.8	-1.1
Blood clot in the leg (DVT)	0.7	0.9	2.6	-0.7	-0.3	1.2	0.9	0.7	-1.2	0.3	0.1	-1.6	1.1	1.0
Body fat percentage	0.7	2.8	7.3	-1.8	-1.6	-1.4	-2.7	-0.7	0.9	-1.2	-1.4	1.5	-2.1	-2.1
Leg fat percentage (right)	0.7	2.6	7.7	-1.3	-1.2	-1.7	-2.8	-0.0	1.7	-0.9	-0.8	1.8	-1.8	-1.9
Medication: Omeprazole	0.7	0.8	1.8	1.2	-0.2	0.5	0.4	1.4	0.2	0.8	1.3	0.2	1.3	1.0
Mean time to correctly identify matches	0.7	1.3	3.3	0.3	1.8	1.6	1.8	0.8	-0.9	0.8	0.2	-0.9	1.0	1.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.3	-0.6	-1.2	-1.1	-0.4	-1.5	-0.9	-1.2	-1.1	-0.8	-0.7	-0.2
Arm fat percentage (left)	0.7	2.9	8.0	-1.8	-1.8	-1.4	-2.8	-0.8	0.8	-1.3	-1.4	1.3	-2.1	-2.1
Medication for cholesterol	0.7	1.0	4.2	2.0	-0.1	0.2	1.5	-0.3	-0.7	0.3	1.4	0.7	0.7	1.0
Medication: Gliclazide	0.7	0.8	2.6	0.6	1.5	-0.5	-0.2	1.6	1.3	0.6	0.9	0.0	0.5	-0.4
Average weekly champagne plus white wine intake	0.7	1.0	4.4	0.7	0.3	-0.9	-0.1	1.2	2.1	0.6	0.8	1.4	0.8	0.2
Ever taken oral contraceptive pill	0.7	0.8	2.2	-0.2	-0.2	1.3	1.1	0.5	-1.5	0.2	-0.1	-1.5	0.8	1.0
Leg fat percentage (left)	0.7	2.6	7.7	-1.4	-1.3	-1.7	-2.8	-0.1	1.7	-1.0	-0.8	1.7	-1.8	-2.0
Ever depressed for a whole week	0.7	0.9	2.1	1.0	1.1	0.4	0.3	1.0	1.4	1.3	1.3	0.8	0.6	0.4
Commuting to job workplace: Cycle	0.7	0.8	2.5	1.1	1.3	-0.7	0.3	0.4	1.4	0.7	0.8	1.6	0.2	0.4
Pack years of smoking	0.7	1.1	3.5	-1.1	-1.9	0.0	-1.0	-0.9	-0.8	-1.2	-1.0	-0.9	-0.9	-0.8
Body Mass Index (BMI) (2010)	0.6	0.8	3.5	0.6	0.0	-0.5	-1.1	0.2	1.5	0.3	0.7	1.9	-0.6	-0.6
Coronary Artery Disease (CAD)	0.6	0.7	2.3	0.0	0.7	-1.5	-0.6	1.0	1.5	-0.2	-0.3	0.7	-0.3	-0.5
Blood Eosinophil Count	0.6	4.7	15.6	-2.5	-2.8	2.7	0.8	0.7	-3.3	-0.3	-0.6	-4.0	1.6	0.4
Lung FEV1/FVC ratio	0.6	3.0	10.0	2.2	1.4	-2.0	-1.1	1.6	3.2	1.1	1.2	2.0	0.3	1.1
Trunk fat percentage	0.6	2.4	5.6	-2.0	-1.6	-1.0	-2.4	-0.9	0.3	-1.2	-1.5	0.9	-2.0	-2.0
Body mass index (BMI)	0.6	2.5	7.3	-1.5	-1.6	-1.7	-2.7	-0.8	0.9	-1.2	-1.1	0.9	-2.0	-1.8
Neuroticism score	0.6	1.3	3.0	1.1	1.1	0.8	1.3	1.0	0.2	1.1	0.9	-1.1	1.4	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.6	-0.2	-1.1	-1.3	-1.6	-0.4	1.0	-0.9	-0.8	1.0	-1.2	-0.9
Lung cancer (father)	0.6	0.7	1.4	-1.2	-0.6	-0.2	-0.9	-0.8	0.5	-0.8	-1.2	0.7	-1.0	-0.8
Arm fat mass (right)	0.6	2.5	6.9	-1.6	-1.7	-1.4	-2.6	-0.8	0.8	-1.3	-1.2	1.1	-2.0	-1.9
Worry too long after embarrassment	0.6	1.1	3.1	1.1	0.4	0.8	1.3	0.4	-0.3	0.9	0.9	-1.4	1.1	1.8
Wheeze or whistling in the chest in last year	0.6	1.0	3.0	0.3	-1.4	-0.7	-1.6	0.8	1.7	-0.0	0.7	1.4	-0.3	-0.2
Health satisfaction	0.6	0.8	2.1	-0.7	-1.2	-1.0	-1.4	-0.3	0.0	-0.7	-1.0	0.3	-1.0	-0.9
Whole body fat mass	0.6	2.5	6.3	-1.7	-1.7	-1.2	-2.5	-0.9	0.5	-1.2	-1.3	1.0	-2.0	-2.0
Had major operations	0.6	0.7	2.6	-0.7	-0.4	-0.1	-1.3	0.0	0.5	-0.3	-0.8	1.6	-1.0	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.7	0.7	0.4	1.3	0.0	1.1	0.0	1.2	0.9	1.0	0.6	0.5
Eye problems/disorders: Cataract	0.6	0.7	2.1	-0.8	-0.4	-0.5	-0.1	-1.4	-0.6	-1.2	-1.1	-0.1	-0.9	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.6	1.9	0.9	0.7	0.5	0.3	0.4	1.2	1.4	1.2	0.3	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	0.7	0.5	1.3	0.9	0.2	-1.1	1.1	0.6	-0.4	0.7	0.9
Illnesses of father: High blood pressure	0.6	0.7	2.3	-1.3	-0.8	-0.7	-1.5	0.3	0.3	-0.4	-0.7	-0.9	-0.4	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.6	-0.8	-0.5	1.1	0.8	0.3	-1.3	0.0	-0.1	-1.6	0.9	0.8
Mean Putamen Volume	0.5	0.6	2.4	-0.8	-1.5	-0.7	-0.6	-0.6	-0.2	-1.1	-0.5	0.1	-0.6	-0.7
Blood Platelet Count	0.5	6.1	19.9	-3.2	-3.5	-2.0	-4.5	0.1	1.9	-2.1	-2.2	0.2	-1.8	-2.1
BMI	0.5	3.2	9.5	-1.7	-2.0	-1.8	-3.1	-0.0	1.5	-1.2	-0.7	1.5	-1.9	-2.3
Number of treatments/medications taken	0.5	0.9	3.3	0.5	-0.0	0.3	-1.1	1.3	1.5	0.7	0.9	1.8	-0.0	-0.3
Angina	0.5	0.6	2.0	0.3	-0.8	-0.4	-1.1	1.2	1.4	0.1	0.3	1.1	0.0	-0.3
Diabetes (father)	0.5	0.6	1.1	-0.8	0.5	-1.0	-1.0	-0.3	0.6	-0.3	-1.0	-0.0	-0.8	-1.0
Trunk fat mass	0.5	2.2	5.7	-1.7	-1.5	-1.1	-2.4	-0.8	0.5	-1.1	-1.4	0.9	-1.9	-2.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.2	1.3	-1.5	-0.2	-0.0	-0.1	0.5	0.0	1.1	0.9	0.2	0.9
Number of live births	0.5	0.7	2.4	-0.6	-1.6	-0.3	-0.6	-0.2	-1.0	-1.0	-0.6	-1.5	-0.4	-0.3
Medication: Amlodipine	0.5	0.7	1.9	-0.7	-0.1	-1.2	-0.8	-0.7	0.7	-0.8	-1.4	0.3	-1.0	-0.5
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.6	-0.7	0.7	1.3	0.1	1.6	0.3	1.0	0.1	-0.0	0.8	-0.2
Eye problems/disorders: None of the above	0.5	0.6	1.5	0.5	0.6	0.4	0.9	0.8	-0.4	0.6	1.0	-1.2	0.9	0.6
Angina (self-reported)	0.5	0.6	2.0	0.3	-0.6	-0.2	-0.9	1.4	1.4	0.3	0.4	1.1	0.2	-0.1
Leg fat mass (right)	0.5	1.9	5.8	-1.3	-1.3	-1.2	-2.4	-0.4	1.0	-0.8	-0.8	1.2	-1.7	-1.8
Alcohol intake frequency.	0.5	1.1	2.4	-0.5	0.2	-1.4	-1.6	-0.6	0.8	-0.8	-1.2	1.0	-1.5	-1.4
Age at last live birth	0.5	0.7	2.3	-0.1	-0.7	-1.5	-1.0	-0.5	1.1	-0.7	-1.0	0.6	-0.5	0.2
Average weekly red wine intake	0.5	0.7	1.3	0.5	1.0	0.6	0.8	1.0	0.7	1.1	1.2	0.7	0.9	0.5
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.6	-0.2	1.0	1.2	1.1	0.6	-0.7	0.6	0.2	-0.7	0.9	0.3
Illnesses of father: None of the above (group 1)	0.5	0.6	1.6	0.1	-1.0	-0.8	-0.8	-1.0	0.4	-0.9	-0.4	1.3	-1.0	-0.4
Arm fat mass (left)	0.5	2.1	5.4	-1.5	-1.7	-1.2	-2.3	-0.9	0.4	-1.2	-1.1	0.8	-1.9	-1.7
Commuting to job workplace: Public transport	0.5	0.6	2.1	-1.4	-0.1	0.4	0.2	-0.5	-0.9	-0.6	-0.8	-1.4	-0.0	-0.8
Medication: Blood pressure	0.5	0.9	2.4	-0.4	1.5	1.2	0.4	1.2	0.3	1.1	0.3	-1.3	0.8	0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.3	0.8	-0.2	1.0	0.8	0.8	-0.6	0.5	1.1	-0.4	1.1	1.0
Leg fat mass (left)	0.5	2.1	6.1	-1.4	-1.5	-1.2	-2.5	-0.5	0.9	-1.0	-0.9	1.1	-1.8	-1.9
Neuroticism (Nagel 2018)	0.4	0.9	1.6	0.8	1.1	1.0	1.2	1.1	0.4	1.0	0.7	-0.4	1.3	1.2
Alzheimer’s Disease (including proxy)	0.4	0.6	1.9	0.9	0.5	1.2	0.5	0.5	-0.4	1.0	1.4	0.1	0.6	0.6
Reaction Time	0.4	0.7	1.7	-0.3	1.1	1.1	1.1	0.0	-1.3	0.2	-0.6	-1.2	0.3	0.6
Verbal and Numeric Reasoning (VNR)	0.4	0.8	5.2	0.1	0.6	-0.9	0.0	-0.6	1.3	-0.2	0.1	2.3	-0.5	-0.6
Bipolar Disorder (2011)	0.4	0.4	1.7	-0.3	0.1	1.0	0.6	-0.6	-1.3	0.0	-0.4	-0.7	0.0	0.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	0.9	1.2	0.5	0.0	0.9	0.6	0.7	0.7	0.7	0.3	0.4
Relative age of first facial hair	0.4	0.8	2.5	0.9	-0.4	0.9	1.1	-0.0	-1.6	0.2	0.6	-0.9	0.8	1.0
Vitamin and mineral supplements	0.4	0.5	2.7	-0.7	1.6	0.2	0.7	-0.3	-0.4	0.2	-1.2	-0.5	-0.3	-0.4
Medication: Metformin	0.4	0.6	2.1	-1.0	-0.6	-0.4	-1.2	0.4	0.7	-0.5	-0.2	0.4	-0.5	-1.4
Severe depression (siblings)	0.4	0.5	2.4	1.0	-0.8	0.8	0.4	-0.0	-0.0	0.3	1.6	0.2	0.6	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.0	0.8	0.4	1.0	0.3	1.0	0.2	1.0	0.9	-0.0	0.7	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	3.8	-0.1	-0.1	-0.9	-0.9	1.5	2.0	0.5	0.7	1.3	0.5	-0.6
Supplements: Glucosamine	0.4	0.5	1.1	-0.1	-1.0	-0.9	-1.0	0.4	0.8	-0.1	0.6	0.9	-0.3	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	0.2	-0.8	0.9	0.7	-0.1	-0.8	0.3	0.4	-0.5	0.8	1.1
Nervous feelings	0.4	0.7	1.8	1.1	1.2	-0.0	0.8	0.8	0.7	0.6	0.4	-0.5	0.9	1.3
Qualifications: None of the above	0.4	0.8	1.7	-1.2	-0.6	0.0	-0.3	-0.9	-1.2	-1.1	-1.0	-1.3	-0.6	-0.3
Hip circumference	0.4	1.6	4.1	-1.4	-1.4	-1.1	-2.0	-0.9	0.4	-1.1	-0.7	0.3	-1.7	-1.8
Falls in the last year	0.4	0.6	1.5	0.8	-0.1	0.6	0.5	0.8	0.4	0.8	1.1	1.2	0.6	0.5
Peak expiratory flow (PEF)	0.4	0.9	4.0	0.6	-0.8	-2.0	-1.2	-0.3	1.2	-0.5	-0.0	0.8	-0.6	-0.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	2.2	-0.8	0.4	-1.5	-1.0	1.1	1.3	-0.1	0.4	0.1	-0.2	-1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.4	0.4	-0.8	-0.8	-0.9	-0.3	1.0	-0.5	0.1	1.2	-0.5	-0.1
Age at first live birth	0.4	0.7	1.8	0.9	0.5	-0.5	0.1	0.7	1.4	0.6	0.4	1.4	0.6	0.9
Shortness of breath walking on level ground	0.4	0.4	1.2	0.1	0.7	0.9	0.3	1.1	-0.1	1.0	0.7	-0.2	0.7	0.1
Mood swings	0.4	0.7	1.8	-0.8	-1.2	-0.0	-0.3	-1.0	-0.9	-1.0	-0.7	-1.4	-0.5	-0.1
Mineral and other dietary supplements	0.4	0.6	3.2	0.5	1.8	0.5	0.9	-0.1	-0.7	0.8	-0.2	-0.6	0.2	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.0	0.6	-0.1	1.0	0.8	0.2	-0.7	0.5	0.8	-1.0	0.8	0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.8	-0.6	-1.7	-0.2	-0.9	0.2	0.4	-0.7	0.3	0.3	-0.2	-0.6
Irritability	0.4	0.7	1.5	1.1	0.7	0.2	1.1	0.4	-0.7	0.6	0.6	-0.6	1.0	1.2
Unable to work because of sickness or disability	0.4	0.5	3.1	0.4	-1.8	0.1	0.2	-0.4	-0.8	-0.5	0.5	-0.7	0.3	0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.5	-0.5	0.2	1.2	0.7	0.6	-0.9	0.5	0.3	-1.2	0.8	-0.1
Bipolar Disorder (2018)	0.3	0.4	1.8	1.1	0.4	-0.1	-0.2	0.1	0.7	0.4	0.9	1.3	-0.1	0.2
Schizophrenia (2018)	0.3	0.5	1.1	-1.0	0.6	0.7	-0.1	-0.6	-0.9	-0.2	-1.1	-0.5	-0.6	-1.0
Schizophrenia (2014)	0.3	0.6	1.9	-0.6	0.5	1.2	0.6	-0.6	-1.4	-0.3	-0.5	-0.9	-0.2	-0.5
Average weekly spirits intake	0.3	0.4	1.5	-1.0	-1.2	0.3	-0.7	0.1	-0.6	-0.6	-0.0	-0.4	-0.3	-0.7
Sitting height	0.3	2.2	6.1	0.7	1.7	2.2	2.5	0.4	-1.3	1.3	0.3	-1.8	1.4	1.3
Had other major operations	0.3	0.4	1.6	-0.4	0.3	-0.5	-0.7	0.6	1.3	0.2	0.3	0.6	-0.3	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.2	-0.8	-0.4	-1.4	-1.1	0.9	1.5	-0.2	-0.2	0.6	0.0	-0.8
Heart attack	0.3	0.4	1.1	-0.5	-0.1	1.1	0.5	0.5	-0.8	0.2	0.1	-1.0	0.7	-0.1
Hair/balding pattern: Pattern 3	0.3	0.5	1.4	-1.2	0.3	-0.6	-0.7	0.5	0.6	-0.4	-0.9	0.0	-0.3	-1.0
Birth weight	0.3	0.6	1.3	1.2	0.8	-0.2	0.8	-1.1	0.3	0.4	0.5	1.0	-0.1	0.8
Emphysema/chronic bronchitis	0.3	0.3	1.3	-0.0	-0.6	0.7	0.3	-0.3	-1.1	-0.5	0.2	-0.8	-0.2	-0.0
Neck or shoulder pain in last month	0.3	0.5	2.1	0.1	1.5	-0.2	-0.3	-0.1	0.7	0.5	-0.2	1.2	-0.6	-0.6
Medication: Seretide 50 evohaler	0.3	0.4	1.4	-0.1	-0.9	-1.2	-0.7	-0.3	0.2	-0.5	-0.5	0.2	-0.7	-0.2
Heart disease (mother)	0.3	0.3	1.5	0.4	-0.6	-1.2	-0.5	-0.1	0.6	-0.4	-0.1	0.8	-0.3	-0.4
Suffer from ‘nerves’	0.3	0.4	2.0	0.3	-0.3	-0.1	0.5	-0.5	-0.8	-0.4	0.2	-1.4	0.3	0.9
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.6	0.4	-0.2	-0.6	-0.5	-0.2	0.7	-0.0	-0.6	1.3	-0.5	0.1
Knee pain experienced in last month	0.3	0.5	1.2	0.9	-0.8	0.5	0.3	0.5	-0.6	0.2	1.1	-0.4	0.6	1.0
Number of self-reported non-cancer illnesses	0.3	0.6	1.8	0.0	0.1	0.2	-0.8	1.4	1.1	0.5	0.7	1.3	-0.1	-0.5
High cholesterol (Self-reported)	0.3	0.5	1.9	0.1	0.7	0.1	-0.1	1.4	1.0	0.5	0.2	1.2	0.3	-0.1
Medication: Atorvastatin	0.3	0.3	1.0	-0.3	1.0	0.5	0.9	0.4	-0.3	0.6	0.3	-0.5	0.6	0.3
Average weekly beer plus cider intake	0.3	0.4	1.1	-0.2	0.0	-0.7	-0.2	-1.0	-0.5	-0.6	-0.8	-0.3	-0.9	-0.4
Alcohol drinker status: Previous	0.3	0.3	0.9	0.6	0.7	0.9	0.7	0.2	-0.2	0.7	0.8	0.2	0.3	0.4
Bipolar Disorder or Schizophrenia	0.2	0.4	1.9	0.3	1.4	0.1	-0.3	0.1	0.5	0.3	-0.0	1.2	-0.5	-0.8
Depressed Affect (Nagel 2018)	0.2	0.5	0.9	0.5	0.9	0.6	0.7	0.8	0.5	0.9	0.2	0.1	0.9	0.8
Worry (Nagel 2018)	0.2	0.3	1.9	-0.1	0.6	0.2	0.6	0.3	-0.2	-0.1	-0.4	-1.4	0.5	0.5
Alzheimer’s Disease (in mother)	0.2	0.2	0.7	0.3	0.5	0.4	-0.0	0.4	0.2	0.6	0.8	0.4	0.2	-0.0
Crohns Disease (2017)	0.2	0.4	1.8	-0.7	0.3	0.3	0.4	-0.2	-0.8	-0.4	-0.9	-1.3	-0.1	-0.2
Major Depression (MDD)	0.2	0.2	0.8	0.2	0.0	0.3	-0.2	0.5	0.8	0.4	0.9	0.6	0.2	-0.2
Ovarian Cancer	0.2	0.2	0.6	-0.1	0.4	0.0	0.7	-0.4	-0.8	-0.2	-0.3	-0.7	0.2	0.3
Age at First Birth	0.2	0.3	0.9	1.0	0.9	0.3	0.5	0.1	0.3	0.6	0.3	0.5	-0.0	0.4
Height	0.2	3.8	9.4	1.6	1.5	2.4	3.1	1.7	-0.8	1.7	1.5	-1.6	2.5	2.1
Allergy or Eczema	0.2	0.6	1.9	-0.1	0.2	-0.6	-1.0	-0.7	0.4	-0.6	-0.6	0.7	-1.4	-1.1
Cardiovascular Disease	0.2	0.8	3.6	-1.9	-0.6	0.5	-1.1	0.5	-0.1	-0.1	-1.4	-0.9	-0.4	-0.5
Tanning	0.2	2.7	5.5	2.3	1.6	0.8	1.2	2.0	1.1	1.9	2.2	0.6	1.4	1.7
Sensitivity / hurt feelings	0.2	0.4	1.2	0.3	0.1	0.9	0.9	-0.1	-0.3	0.4	0.5	-0.7	0.6	1.1
Medication: Co-codamol	0.2	0.3	1.6	-0.3	-0.3	0.2	-0.4	1.3	0.4	0.3	0.6	0.0	0.5	-0.2
Fed-up feelings	0.2	0.3	1.5	0.9	1.2	0.1	0.5	0.1	0.5	0.5	0.0	0.5	0.1	0.5
High blood pressure	0.2	0.6	2.2	-0.7	0.1	0.2	-1.5	1.0	1.1	0.5	-0.6	0.2	-0.4	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.3	0.6	1.0	-0.1	-0.4	0.0	0.6	0.2	0.1	1.1	-0.7	-0.7
Medication: Atenolol	0.2	0.3	1.0	0.2	0.0	-1.0	-0.6	0.8	1.0	-0.2	-0.1	-0.1	-0.1	-0.5
Medication: Levothyroxine sodium	0.2	0.4	1.3	-0.1	0.5	-0.7	-0.4	1.1	0.8	0.4	0.7	-0.7	0.4	0.1
High blood pressure (mother)	0.2	0.3	0.6	-0.6	-0.6	-0.1	-0.7	-0.6	0.1	-0.6	-0.7	0.4	-0.6	-0.4
Alcohol usually taken with meals	0.2	0.3	0.8	0.4	0.2	0.2	0.7	0.5	0.4	0.4	0.9	0.5	0.7	-0.1
Allergy	0.2	0.4	1.0	-0.7	-1.0	-0.4	0.3	-0.8	-0.7	-0.8	-0.8	-0.9	0.0	0.1
Weight	0.2	0.9	2.6	-0.9	-1.0	-0.8	-1.6	-0.5	0.4	-0.7	-0.7	0.3	-1.3	-1.1
Worrier / anxious feelings	0.2	0.4	1.5	0.2	0.4	0.3	0.2	1.2	0.9	0.1	0.3	-0.8	0.7	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.8	0.6	0.9	0.5	0.6	0.1	-0.6	0.5	0.0	-0.1	0.3	0.4
Medication: Cholesterol lowering	0.2	0.3	1.6	-1.3	-0.7	0.3	0.1	0.6	-0.2	-0.3	-0.3	-0.3	0.5	-0.3
Medication: Lansoprazole	0.2	0.3	1.1	0.1	0.3	0.3	-0.5	-1.0	-0.1	0.2	-0.1	0.9	-0.8	-0.5
Standing height	0.2	2.0	5.1	1.1	1.4	1.9	2.2	0.7	-1.1	1.3	0.8	-1.4	1.4	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.1	0.8	1.1	-0.2	0.0	-0.8	0.4	0.0	0.0	0.5	-0.7	-0.3
Birth weight of first child	0.2	0.4	1.1	0.2	0.7	1.1	1.0	0.6	-0.9	0.3	-0.1	-0.6	0.6	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.7	0.8	1.3	-0.1	0.4	-0.3	0.3	0.4	0.3	0.3	-0.1	0.2
Exposure to tobacco smoke outside home	0.2	0.3	1.1	0.2	-0.1	-0.5	-0.7	1.1	0.8	0.2	0.4	-0.4	0.5	0.5
Comparative body size at age 10	0.2	0.5	2.2	0.8	-1.5	0.1	-0.4	-0.9	-0.6	-0.5	0.9	-0.4	-0.4	0.4
Number of full brothers	0.2	0.2	0.7	-0.1	-0.8	0.2	-0.2	-0.2	-0.7	-0.6	-0.5	-0.4	-0.3	-0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	1.2	-0.7	0.1	-0.6	0.0	-0.7	0.0	-0.9	-1.1	-0.3	-0.6	-0.4
Medication: Blood pressure	0.2	0.3	1.2	-0.7	-1.1	-0.0	-0.9	0.0	-0.3	-0.4	-0.7	-0.2	-0.3	-0.5
Medication: Allopurinol	0.2	0.3	0.9	-1.0	-0.4	-0.4	-0.7	0.1	-0.1	-0.2	-0.8	0.2	-0.4	-0.9
Hypertension (Self-reported)	0.2	0.6	2.5	-1.2	-0.2	-0.0	-1.6	0.6	0.7	0.1	-1.0	-0.3	-0.6	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.0	0.4	0.1	0.8	0.9	0.5	-0.0	0.8	0.7	-0.3	1.0	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.3	0.7	0.5	0.0	0.9	0.1	-0.2	0.5	0.9	-0.3	1.0	1.1
Miserableness	0.2	0.3	1.4	0.2	0.2	-1.2	-0.7	-0.4	0.6	-0.4	-0.5	-0.2	-0.6	-0.1
Medication: Bendroflumethiazide	0.2	0.3	0.8	-0.3	0.9	0.8	-0.1	0.5	-0.0	0.6	-0.3	-0.7	-0.0	-0.0
Medication: Paracetamol	0.2	0.4	0.9	0.7	-0.4	0.7	-0.6	0.7	0.2	0.7	0.7	1.0	0.1	0.5
Medication: Lisinopril	0.2	0.2	0.6	-0.6	0.8	0.1	-0.0	0.6	0.7	0.2	-0.2	0.4	0.1	-0.8
Alcohol drinker status: Never	0.2	0.2	0.6	0.5	-0.5	-0.6	-0.8	-0.1	0.3	-0.0	0.2	0.7	-0.6	-0.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.1	0.5	-0.1	-0.2	1.4	-1.2	-1.4	-0.5	0.4	-0.3	0.3	0.6
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.4	0.1	-0.2	-0.2	-0.3	-0.0	-0.2	0.1	-0.4	-0.1	-0.5
Triglycerides	0.1	0.1	0.7	0.2	0.8	-0.0	0.4	0.3	-0.1	0.1	0.1	0.1	0.1	-0.2
Heel T-Score	0.1	1.0	2.2	-1.5	-1.4	-1.1	-0.9	0.1	-0.2	-1.2	-0.5	-1.4	-0.4	-1.2
Lung FVC	0.1	0.4	1.4	-0.2	1.2	0.0	1.2	-0.1	-0.6	0.3	-0.2	-0.6	0.7	0.8
Chronotype (morning person)	0.1	0.2	0.5	0.3	-0.5	0.4	-0.3	0.4	0.7	0.3	0.7	0.6	0.1	0.0
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	-0.1	-0.2	-0.3	-0.7	-0.2	0.2	-0.3	-0.5	0.2	-0.7	-0.4
Leg fat-free mass (left)	0.1	0.3	0.8	-0.3	-0.6	-0.1	-0.7	-0.7	-0.2	-0.4	-0.4	-0.4	-0.9	-0.6
Relative age voice broke	0.1	0.2	0.5	0.3	0.3	0.1	0.5	0.5	-0.3	0.3	0.1	-0.6	0.7	0.5
Age when periods started (menarche)	0.1	0.3	0.6	0.2	0.7	-0.6	-0.1	-0.6	0.2	-0.1	-0.8	0.7	-0.6	-0.2
Leg predicted mass (left)	0.1	0.3	0.8	-0.4	-0.6	-0.1	-0.7	-0.6	-0.3	-0.4	-0.4	-0.4	-0.9	-0.7
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	-0.0	-0.7	0.1	0.0	-0.6	-0.3	-0.2	0.3	-0.1	-0.3	0.1
Medication: Ramipril	0.1	0.1	0.3	0.2	-0.1	-0.3	-0.2	-0.5	-0.3	0.0	-0.1	-0.6	-0.4	-0.0
Impedance of arm (right)	0.1	0.3	1.3	-0.9	0.6	0.4	0.2	0.2	-0.4	-0.1	-1.1	-0.3	0.2	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.5	0.7	0.3	-0.5	0.1	0.2	0.5	0.4	0.3	-0.3	0.4	0.7
Depression (self-reported)	0.1	0.1	0.5	-0.5	-0.2	0.3	0.0	0.0	-0.1	0.0	-0.2	-0.7	0.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.8	0.9	0.5	-0.5	0.4	-0.2	0.4	0.4	0.4	-0.1	0.3	0.9
Impedance of arm (left)	0.1	0.3	0.5	-0.1	0.6	0.7	0.7	0.5	-0.5	0.3	-0.5	-0.2	0.6	0.4
Breastfed as a baby	0.1	0.1	0.4	0.3	-0.1	0.0	0.0	0.6	-0.0	0.1	0.5	-0.3	0.4	0.0
Hair/balding pattern: Pattern 4	0.1	0.3	1.2	-0.7	1.1	0.2	0.2	0.3	-0.4	0.4	-0.6	-0.7	0.2	-0.3
Pulse wave reflection index	0.1	0.1	0.7	-0.1	-0.3	-0.2	-0.4	0.5	0.8	0.1	0.3	0.5	-0.0	0.1
Headache pain in last month	0.1	0.2	1.0	0.6	-0.0	0.7	0.3	-0.0	-0.6	0.2	0.0	-0.1	0.1	1.0
Gout (self-reported)	0.1	0.1	0.5	-0.7	-0.3	-0.0	-0.4	0.4	-0.2	-0.0	-0.5	-0.2	-0.1	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.3	0.9	0.2	0.4	0.4	0.9	-0.5	-0.6	0.1	0.2	-0.8	0.3	0.7
Arm fat-free mass (right)	0.1	0.3	1.1	0.2	-1.1	-0.2	-0.5	-0.8	-0.2	-0.4	0.3	-0.2	-0.7	-0.4
Medication: Ibuprofen	0.1	0.1	0.3	0.6	0.5	0.5	0.3	0.1	-0.6	0.4	-0.3	0.2	0.1	0.4
Arm predicted mass (right)	0.1	0.3	0.9	0.0	-0.9	-0.3	-0.5	-0.9	-0.2	-0.5	0.1	-0.3	-0.8	-0.5
Medication: Aspirin	0.1	0.1	0.4	-0.1	-0.6	-0.0	-0.4	0.6	0.1	0.1	0.5	-0.2	0.2	-0.7
Illnesses of father: Heart disease	0.1	0.2	0.6	-0.8	0.3	-0.5	-0.1	0.7	0.2	0.1	-0.3	-0.4	0.3	-0.4
Leg fat-free mass (right)	0.1	0.4	0.9	-0.4	-0.7	-0.2	-0.7	-0.9	-0.4	-0.5	-0.4	-0.6	-1.0	-0.7
Osteoarthritis (self-reported)	0.1	0.2	0.6	0.3	-0.8	-0.1	-0.7	-0.0	-0.1	-0.3	-0.1	0.6	-0.4	0.3
Medication: Aspirin	0.1	0.1	0.3	-0.2	-0.3	0.3	-0.0	0.6	-0.2	0.1	0.4	-0.5	0.4	-0.5
Leg predicted mass (right)	0.1	0.3	0.8	-0.4	-0.7	-0.2	-0.6	-0.9	-0.4	-0.5	-0.4	-0.6	-0.9	-0.7
Mother’s age at death	0.1	0.2	0.4	0.2	-0.5	-0.5	0.4	-0.5	-0.5	-0.6	0.1	-0.5	-0.2	-0.0
Basal metabolic rate	0.1	0.5	1.2	-0.5	-0.9	-0.4	-1.0	-0.8	-0.1	-0.7	-0.4	-0.3	-1.1	-0.8
Heart disease (siblings)	0.1	0.2	0.4	-0.2	-0.2	-0.5	-0.5	0.6	0.6	-0.1	-0.3	0.1	-0.2	-0.5
Impedance of whole body	0.1	0.3	1.0	-0.0	1.0	0.7	0.8	0.6	-0.1	0.5	-0.2	0.2	0.7	0.3
Arm predicted mass (left)	0.1	0.4	1.1	-0.3	-0.8	-0.6	-0.9	-0.8	0.3	-0.6	-0.1	0.0	-1.1	-0.8
Hair Pigment	0.0	1.1	4.2	0.1	0.5	-2.1	-0.3	-1.7	0.6	-1.1	-0.7	0.7	-1.2	-0.9
Impedance of leg (right)	0.0	0.2	0.6	-0.1	0.7	0.2	0.3	0.8	0.5	0.3	0.1	0.6	0.4	-0.1
Impedance of leg (left)	0.0	0.1	0.4	-0.2	0.5	-0.1	0.2	0.4	0.6	0.2	-0.0	0.6	0.2	-0.3
Forced vital capacity (FVC)	0.0	0.1	0.3	-0.0	0.3	0.2	0.5	-0.2	-0.1	0.1	0.1	-0.6	0.2	0.2
Trunk fat-free mass	0.0	0.2	0.4	-0.0	-0.4	-0.3	-0.5	-0.4	-0.0	-0.4	0.0	-0.6	-0.6	-0.5
Trunk predicted mass	0.0	0.2	0.4	-0.0	-0.5	-0.3	-0.5	-0.4	0.1	-0.4	0.0	-0.5	-0.6	-0.5
Comparative height size at age 10	0.0	0.2	0.6	0.0	-0.2	-0.3	-0.2	-0.5	-0.1	-0.4	-0.7	0.3	-0.7	-0.8
Whole body fat-free mass	0.0	0.3	0.7	-0.2	-0.6	-0.3	-0.6	-0.7	-0.2	-0.5	-0.2	-0.5	-0.8	-0.6
Whole body water mass	0.0	0.2	0.6	-0.2	-0.6	-0.1	-0.5	-0.7	-0.3	-0.4	-0.1	-0.5	-0.8	-0.5
Arm fat-free mass (left)	0.0	0.2	0.5	-0.1	-0.6	-0.3	-0.6	-0.6	0.1	-0.4	0.0	-0.2	-0.7	-0.5

Hub : Genes

C1orf190

Models

Trait associations