TWAS hub - C20orf135

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0183	0.0096	5.0e-04	0.019	0.004	0.009	NA	0.011	6.1e-05	3.4e-02	4.9e-03	NA	1.7e-03
2	TCGA	Cervical Squamous Cell Carcinoma	0.0560	0.0320	9.3e-03	0.068	0.007	0.023	NA	0.042	2.9e-04	1.5e-01	2.6e-02	NA	3.9e-03
3	TCGA	Colon Adenocarcinoma	0.0700	0.0360	1.0e-03	-0.005	0.055	0.053	NA	0.035	8.2e-01	3.9e-04	4.9e-04	NA	3.9e-03
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0363	0.0195	6.3e-04	0.023	0.024	0.018	NA	0.014	1.0e-03	9.1e-04	3.4e-03	NA	9.4e-03
5	TCGA	Brain Lower Grade Glioma	0.1899	0.0572	0.0e+00	0.182	0.183	0.178	NA	0.181	3.2e-20	2.5e-20	8.8e-20	NA	3.7e-20
6	TCGA	Lung Squamous Cell Carcinoma	0.0682	0.0336	5.8e-06	0.039	0.046	0.032	NA	0.035	2.7e-05	5.9e-06	1.4e-04	NA	7.1e-05
7	TCGA	Pheochromocytoma and Paraganglioma	0.1190	0.0660	5.8e-03	0.010	0.023	0.034	NA	0.017	1.3e-01	4.2e-02	1.6e-02	NA	6.5e-02
8	TCGA	Prostate Adenocarcinoma	0.1277	0.0491	4.7e-07	0.063	0.062	0.060	NA	0.056	3.8e-07	4.6e-07	7.0e-07	NA	1.5e-06
9	TCGA	Thyroid Carcinoma	0.0950	0.0450	1.8e-05	0.054	0.063	0.055	NA	0.053	5.3e-06	9.2e-07	4.5e-06	NA	6.2e-06
10	TCGA	Uterine Corpus Endometrial Carcinoma	0.1090	0.0630	9.4e-03	0.031	0.011	0.024	NA	0.053	4.6e-02	1.5e-01	6.9e-02	NA	1.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Ulcerative Colitis	7.9	11.4	21.7	3.0	3.0	3.9	4.7	3.0	3.4	3.0	3.8	2.2	3.0
Number of full sisters	7.4	9.0	11.9	-3.4	-3.4	-2.8	-2.7	-3.4	-3.3	-1.2	-2.8	-2.9	-3.4
Ever had hysterectomy (womb removed)	7.3	8.2	10.5	-2.7	-2.7	-3.2	-3.1	-2.8	-3.0	-2.5	-3.2	-2.6	-2.7
Angina	7.2	9.5	15.7	-3.3	-3.3	-2.7	-3.3	-2.6	-3.7	-4.0	-2.2	-2.0	-3.2
Angina (self-reported)	6.9	9.1	16.3	-3.1	-3.1	-2.7	-3.3	-2.4	-3.7	-4.0	-2.1	-1.9	-3.1
Length of working week for main job	6.2	6.8	8.6	2.9	2.9	2.6	2.5	2.9	2.2	1.6	2.7	2.5	2.9
Irritable Bowel Disease (IBD)	4.4	10.6	24.4	3.0	3.1	3.2	4.9	3.3	3.2	2.5	3.5	1.5	3.2
Ulcerative Colitis (UC)	4.4	8.3	16.8	2.9	2.9	2.9	4.1	2.8	3.1	2.1	2.9	1.3	2.9
Medication: Paracetamol	4.0	6.6	13.0	-2.3	-2.3	-2.3	-1.8	-2.3	-2.5	-3.6	-3.0	-2.7	-2.3
High blood pressure (siblings)	3.6	5.2	8.6	-2.4	-2.3	-2.1	-2.9	-2.7	-2.6	-1.2	-2.1	-1.8	-2.3
Medication: Bendroflumethiazide	3.6	5.5	7.8	-2.7	-2.7	-2.0	-2.2	-2.6	-2.8	-1.3	-1.9	-2.0	-2.7
Rheumatoid Arthritis	3.5	4.8	8.1	2.1	2.1	2.7	2.8	1.7	2.5	2.2	2.0	1.4	2.1
Average weekly spirits intake	3.1	3.9	6.6	1.8	1.8	2.4	2.6	1.7	2.5	1.8	1.7	1.3	1.8
Medication: Lansoprazole	3.0	3.4	4.9	-2.0	-2.0	-2.0	-1.5	-2.2	-1.6	-0.7	-1.7	-2.2	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.9	3.4	4.3	2.1	2.0	2.1	2.0	2.0	1.6	0.7	1.8	1.9	2.0
Mother’s age at death	2.6	3.3	5.5	2.0	2.0	1.6	1.7	2.3	1.5	0.7	2.0	1.7	2.0
Multivitamins +/- minerals	2.5	3.2	8.7	-1.5	-1.5	-1.9	-1.7	-1.1	-2.0	-3.0	-1.7	-1.4	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.2	6.8	2.2	2.2	2.6	2.4	2.3	1.8	2.2	2.4	2.3	2.2
Age at First Birth	2.4	3.4	5.5	-1.8	-1.7	-2.2	-2.3	-2.0	-1.5	-0.5	-2.3	-1.6	-1.8
Medication: Paracetamol	2.4	3.8	5.1	-1.8	-1.8	-1.8	-1.5	-2.0	-1.9	-2.3	-2.3	-2.2	-1.8
Medication: Lisinopril	2.4	3.2	5.1	-1.9	-1.9	-1.0	-1.6	-1.7	-2.2	-1.8	-2.0	-1.3	-1.9
Medication: Amlodipine	2.3	3.2	5.1	-2.0	-2.0	-1.2	-1.6	-1.7	-2.3	-2.2	-1.5	-1.3	-1.9
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	3.8	1.9	1.9	1.8	1.2	1.9	1.2	-0.8	1.6	1.7	1.8
Sensitivity / hurt feelings	2.2	3.8	5.1	-1.9	-1.9	-2.0	-1.9	-1.9	-1.9	-2.0	-2.3	-1.8	-1.8
Medication: Atorvastatin	2.2	2.7	5.1	-1.9	-1.9	-1.5	-1.8	-1.4	-2.3	-1.3	-1.0	-1.0	-1.9
HbA1C	2.1	2.3	3.4	1.8	1.8	1.4	0.9	1.4	1.5	0.7	1.5	1.9	1.8
Vitamin and mineral supplements	2.1	2.9	7.6	1.4	1.4	1.8	1.6	1.2	1.8	2.8	1.8	1.5	1.4
Exposure to tobacco smoke at home	2.1	2.3	5.7	-1.7	-1.7	-1.2	-0.5	-1.4	-0.8	-1.2	-1.7	-2.4	-1.7
Medication: Co-codamol	1.9	2.2	2.5	-1.6	-1.6	-1.6	-1.2	-1.6	-1.4	-1.1	-1.3	-1.6	-1.6
Supplements: Fish oil (including cod liver oil)	1.9	2.5	3.9	-1.7	-1.7	-1.6	-1.3	-1.2	-2.0	-1.7	-1.3	-1.5	-1.7
Townsend deprivation index at recruitment	1.8	2.5	4.0	-1.6	-1.6	-2.0	-1.7	-1.7	-1.2	-1.0	-1.7	-1.5	-1.6
Stomach or abdominal pain in last month	1.8	2.3	4.3	1.6	1.5	1.6	2.1	1.6	1.9	0.7	1.1	1.0	1.5
Bipolar Disorder (2018)	1.7	2.6	3.9	-1.9	-2.0	-1.6	-1.4	-1.6	-1.8	-1.0	-1.2	-1.6	-1.9
Crohns Disease (2012)	1.7	2.7	7.1	1.2	1.2	1.5	2.7	1.5	1.5	1.8	2.2	0.7	1.3
Birth weight of first child	1.7	3.0	6.3	1.5	1.4	1.7	2.3	1.4	2.2	2.5	1.3	0.9	1.4
Tinnitus: Yes, now most or all of the time	1.7	2.0	6.7	-0.9	-0.9	-1.5	-1.8	-0.8	-1.7	-2.6	-1.2	-0.6	-0.9
Pain type(s) experienced in last month: Hip pain	1.7	2.1	6.4	0.7	0.7	1.7	2.5	0.7	1.7	2.5	0.9	0.2	0.7
Blood Red Count	1.6	15.4	28.7	4.0	3.9	5.4	3.7	3.0	4.0	2.8	4.0	4.2	3.8
Mean time to correctly identify matches	1.6	3.1	5.2	1.7	1.6	2.3	2.3	1.3	2.0	1.4	1.7	1.5	1.6
Pulse rate, automated reading	1.6	5.1	11.1	-2.7	-2.7	-1.7	-0.6	-2.7	-1.1	0.6	-2.3	-3.3	-2.7
Medication: Gliclazide	1.6	1.8	2.7	-1.6	-1.6	-0.9	-1.1	-1.7	-1.5	0.1	-1.3	-1.2	-1.6
Myopia	1.6	2.3	4.0	1.5	1.5	1.4	0.8	1.5	1.3	2.0	1.5	1.9	1.5
High blood pressure	1.5	4.1	13.6	-1.8	-1.9	-0.9	-1.9	-1.5	-3.0	-3.7	-0.9	-0.6	-1.8
High blood pressure (mother)	1.5	2.1	5.1	-1.0	-1.0	-1.7	-1.7	-1.1	-2.3	-2.0	-1.2	-0.8	-0.9
Supplements: Vitamin C	1.5	1.8	3.8	-0.9	-0.9	-1.8	-2.0	-1.1	-1.6	-1.7	-1.3	-0.7	-0.9
Ever had bowel cancer screening	1.5	1.8	2.4	1.5	1.5	1.2	1.3	1.5	1.4	0.4	1.4	1.1	1.5
Pain experienced in last month	1.5	2.4	9.4	-0.1	0.0	-1.6	-2.9	0.2	-1.7	-3.1	-0.5	0.9	-0.0
Shortness of breath walking on level ground	1.4	1.7	3.1	-1.6	-1.5	-0.5	-0.2	-1.7	-0.8	0.0	-1.6	-1.8	-1.6
Hypertension (Self-reported)	1.4	4.0	12.8	-1.9	-1.9	-0.9	-1.8	-1.5	-3.0	-3.6	-0.8	-0.7	-1.9
Crohns Disease (2017)	1.3	2.9	10.1	1.1	1.2	1.3	3.2	1.7	1.6	1.7	2.0	0.1	1.3
Severe depression (siblings)	1.3	1.4	3.1	-1.3	-1.4	-0.5	-0.0	-1.8	-0.5	1.0	-1.2	-1.6	-1.4
Medication: Ramipril	1.3	1.6	3.5	1.1	1.1	1.9	1.6	1.1	1.1	0.9	1.4	1.2	1.1
Illnesses of siblings	1.3	1.8	3.8	1.4	1.3	1.2	2.0	1.5	1.9	1.0	0.9	0.6	1.2
Risk taking	1.3	1.9	3.7	1.3	1.3	1.3	1.9	1.2	1.2	1.7	1.6	0.7	1.3
Reaction Time	1.2	2.3	4.5	1.4	1.3	2.1	1.9	1.1	1.6	1.4	1.4	1.5	1.3
Lupus	1.2	1.8	6.4	-0.7	-0.8	-1.4	-2.2	-0.4	-1.7	-2.5	-0.6	0.1	-0.8
Primary Biliary Cirrhosis	1.2	1.7	4.9	1.0	1.0	2.0	2.2	1.3	1.1	0.6	1.2	0.7	1.0
Systolic blood pressure, automated reading	1.2	3.4	14.3	-1.4	-1.4	-1.1	-2.0	-1.0	-2.6	-3.8	-0.7	-0.3	-1.4
Heart attack	1.2	1.6	4.0	-1.4	-1.4	-0.8	-0.6	-1.0	-1.0	-2.0	-1.2	-1.2	-1.4
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	2.7	-1.5	-1.6	-0.7	0.1	-1.4	-0.9	1.5	-0.8	-1.4	-1.6
Lung cancer (father)	1.2	1.4	1.9	-0.9	-0.9	-1.2	-1.3	-1.3	-1.1	-1.4	-1.3	-1.4	-0.9
Leg fat percentage (right)	1.2	4.3	11.5	-2.7	-2.7	-0.7	0.8	-2.3	-0.8	1.0	-1.6	-3.4	-2.6
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.9	1.2	1.2	1.1	1.4	0.9	1.7	1.1	0.8	0.3	1.2
Financial situation satisfaction	1.2	1.5	3.2	1.0	0.9	1.7	1.8	1.0	1.5	1.2	1.0	0.7	0.9
Coronary Artery Disease (CAD)	1.1	1.3	1.9	1.3	1.2	1.4	1.1	1.1	0.9	0.6	1.3	1.3	1.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.0	1.3	1.3	1.3	1.4	1.1	1.1	-0.3	0.8	1.1	1.3
Arm fat percentage (right)	1.1	4.4	9.6	-2.7	-2.7	-1.1	0.4	-2.3	-1.1	1.3	-1.6	-3.1	-2.7
Medication for pain relief, constipation, heartburn	1.1	1.8	6.0	1.4	1.5	0.2	-0.9	1.2	0.5	1.2	1.5	2.4	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.1	-1.4	-1.3	-1.0	-0.5	-1.1	-1.2	-0.5	-1.0	-1.5	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.0	0.9	0.9	0.9	0.5	0.6	1.1	2.0	1.1	1.3	0.9
Number of self-reported non-cancer illnesses	1.1	2.0	5.0	-1.4	-1.4	-1.1	-0.8	-1.0	-1.8	-2.2	-1.1	-1.2	-1.4
Leg fat percentage (left)	1.1	4.1	10.9	-2.6	-2.6	-0.5	1.1	-2.2	-0.6	1.3	-1.5	-3.3	-2.5
Irritability	1.1	1.8	3.1	-1.1	-1.1	-1.8	-1.2	-1.6	-1.0	-0.6	-1.7	-1.7	-1.1
Vascular/heart problems diagnosed by doctor	1.1	3.0	11.3	1.6	1.6	0.6	1.5	1.1	2.5	3.4	0.6	0.5	1.6
Supplements: Calcium	1.1	1.2	2.6	1.3	1.3	0.3	-0.2	1.4	-0.2	-0.9	1.2	1.6	1.3
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.0	-1.1	-1.1	-1.0	-0.9	-1.0	-1.4	-0.7	-1.2	-1.4	-1.1
Current tobacco smoking	1.0	1.6	5.5	0.9	0.9	1.5	2.3	0.5	1.9	1.4	0.4	-0.3	0.9
Taking other prescription medications	1.0	1.5	3.1	-1.3	-1.4	-0.9	-0.1	-1.2	-0.8	-1.3	-1.4	-1.7	-1.4
Peak expiratory flow (PEF)	1.0	2.4	3.6	1.8	1.9	1.8	1.6	1.5	1.3	0.2	1.2	1.3	1.9
Medication: Blood pressure	1.0	1.8	4.9	-1.3	-1.2	-0.7	-1.3	-1.0	-1.9	-2.2	-0.9	-0.8	-1.2
Arm fat percentage (left)	1.0	3.9	8.9	-2.6	-2.6	-0.8	0.7	-2.1	-0.9	1.5	-1.4	-3.0	-2.5
Breast Cancer	0.9	2.2	3.0	-1.7	-1.7	-1.4	-1.1	-0.9	-1.5	-1.7	-1.3	-1.6	-1.7
Diabetes (father)	0.9	1.2	2.2	-1.3	-1.3	-0.8	-1.0	-1.5	-0.7	0.4	-0.9	-1.1	-1.3
Pack years adult smoking proportion	0.9	1.4	3.5	-1.4	-1.5	-0.7	0.0	-1.1	-0.8	-0.6	-1.1	-1.9	-1.5
Eye problems/disorders: None of the above	0.9	1.0	3.0	0.7	0.7	1.7	1.5	0.5	1.2	1.1	0.7	0.3	0.7
Medication: Seretide 50 evohaler	0.9	1.0	2.7	0.9	0.8	1.5	1.6	1.1	1.1	0.2	0.5	0.2	0.8
Comparative height size at age 10	0.9	5.1	5.9	2.3	2.3	2.4	2.1	2.0	2.3	2.2	2.2	2.4	2.3
Miserableness	0.9	1.6	2.9	-1.2	-1.2	-1.4	-0.9	-1.6	-0.8	-0.1	-1.7	-1.6	-1.2
Medication: Blood pressure	0.9	1.8	7.6	-1.1	-1.2	-0.2	-1.1	-0.9	-2.0	-2.7	-0.4	-0.2	-1.2
Commuting to job workplace: Cycle	0.9	1.1	2.9	-1.0	-0.9	-1.0	-1.7	-1.1	-1.1	-0.6	-1.0	-0.2	-1.0
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.0	-1.2	-1.3	-0.6	-0.4	-0.9	-0.8	-1.7	-1.1	-1.1	-1.2
Pack years of smoking	0.9	1.3	3.5	-1.4	-1.4	-0.8	-0.0	-1.0	-0.8	-0.8	-1.0	-1.9	-1.4
Alzheimer’s Disease (in mother)	0.8	1.0	2.1	0.6	0.6	1.2	1.5	0.9	1.1	1.4	0.9	0.5	0.6
Medication for hormone replacement therapy	0.8	0.8	2.3	-0.6	-0.6	-0.8	-0.9	-0.4	-1.2	-1.5	-1.0	-0.9	-0.6
Body mass index (BMI)	0.8	3.5	8.5	-2.4	-2.4	-0.6	0.7	-1.8	-1.4	-0.7	-1.6	-2.9	-2.4
Alcohol usually taken with meals	0.8	1.3	2.1	1.4	1.5	1.1	0.4	1.3	0.5	-0.6	1.1	1.3	1.4
Mouth/teeth dental problems	0.8	1.2	1.8	1.2	1.3	1.2	0.7	1.3	0.9	0.4	1.0	1.2	1.3
Happiness	0.8	1.0	3.1	0.7	0.6	1.2	1.8	0.8	1.3	0.8	0.9	0.2	0.7
Medication: Cholesterol lowering	0.8	1.2	3.5	-1.2	-1.2	-0.9	-1.2	-0.7	-1.9	-0.9	-0.3	-0.5	-1.1
Standing height	0.8	8.3	12.1	3.1	3.1	2.5	1.9	2.7	2.6	3.1	3.0	3.5	3.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.4	1.1	1.1	0.7	1.2	0.7	1.8	1.8	0.4	0.4	1.0
Body fat percentage	0.8	3.1	7.1	-2.0	-2.0	-0.1	1.6	-1.7	-0.1	2.4	-0.9	-2.7	-2.0
Number of children fathered	0.8	0.9	1.8	0.9	0.9	0.9	0.7	0.9	0.8	0.3	1.3	1.3	1.0
Qualifications: College or University degree	0.8	2.4	6.8	1.8	1.8	0.4	-0.9	1.8	0.7	-0.0	1.5	2.6	1.8
Leg fat mass (right)	0.8	3.0	8.3	-2.2	-2.2	-0.2	1.3	-1.7	-0.5	0.9	-1.3	-2.9	-2.1
Age at last live birth	0.8	1.2	3.5	1.2	1.2	0.2	-0.4	1.4	0.5	0.2	1.3	1.9	1.2
Medication: Aspirin	0.8	1.1	2.0	-1.4	-1.4	-0.3	-0.5	-1.0	-1.2	-0.7	-0.7	-1.2	-1.4
Knee pain experienced in last month	0.8	1.3	5.4	0.3	0.3	1.0	2.1	0.1	1.0	2.3	0.8	-0.3	0.3
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.9	0.7	0.7	1.1	1.7	0.9	0.9	1.0	1.0	0.2	0.7
Qualifications: nursing, teaching	0.8	1.3	2.2	1.4	1.4	0.7	0.5	1.4	1.2	-0.2	1.0	1.3	1.5
Number of treatments/medications taken	0.7	1.3	2.5	-1.2	-1.3	-0.7	-0.1	-1.1	-1.3	-1.3	-0.9	-1.6	-1.3
Medication: Atenolol	0.7	0.9	6.6	-0.5	-0.4	0.0	-0.3	-0.2	-1.0	-2.6	-0.3	-0.4	-0.4
Chronic bronchitis/emphysema (father)	0.7	0.8	1.5	-1.0	-1.0	-0.2	0.5	-1.2	-0.0	1.0	-0.8	-1.2	-1.0
Had other major operations	0.7	0.8	2.2	-0.6	-0.6	-1.2	-0.6	-0.9	-0.3	-0.6	-1.4	-1.5	-0.6
Prospective memory result	0.7	0.9	1.4	1.2	1.2	0.6	1.1	1.0	1.0	0.7	0.7	0.6	1.2
Wheeze or whistling in the chest in last year	0.7	1.2	5.5	0.0	0.0	0.7	2.3	-0.2	1.6	1.5	0.0	-1.0	0.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.6	-1.0	-1.0	-0.9	-0.7	-1.3	-0.5	0.3	-0.9	-0.9	-1.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.3	0.7	0.7	1.5	1.5	0.8	0.7	0.2	0.8	0.3	0.6
Commuting to job workplace: Walk	0.7	0.7	2.6	0.6	0.6	0.6	0.0	0.9	-0.5	0.1	1.4	1.6	0.7
Breast cancer (self-reported)	0.7	0.9	1.2	1.1	1.1	0.9	0.7	0.8	1.0	0.9	0.8	1.1	1.0
Smoking status: Current	0.7	1.1	3.5	0.9	0.8	1.2	1.9	0.5	1.6	1.2	0.3	-0.2	0.8
Wears glasses or contact lenses	0.7	0.8	1.9	1.1	1.2	0.3	-0.1	0.9	0.5	-0.3	0.7	1.4	1.2
Impedance of whole body	0.7	3.5	20.1	1.3	1.3	0.6	0.5	0.7	2.0	4.5	1.5	1.4	1.3
Leg fat mass (left)	0.7	2.9	7.9	-2.1	-2.1	-0.1	1.4	-1.7	-0.5	1.1	-1.2	-2.8	-2.1
Neuroticism	0.6	1.4	2.4	-1.0	-1.1	-1.1	-0.9	-1.2	-1.0	-1.4	-1.6	-1.3	-1.1
Chronotype (morning person)	0.6	1.4	5.7	-1.0	-1.0	-0.8	-0.5	-0.5	-1.3	-2.4	-0.7	-1.4	-0.9
Supplements: Zinc	0.6	0.7	1.8	-0.6	-0.6	-0.8	-1.3	-0.9	-1.3	-0.7	-0.6	-0.2	-0.7
Trunk fat percentage	0.6	2.4	8.8	-1.5	-1.5	0.2	1.7	-1.2	0.2	3.0	-0.4	-2.0	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.7	-0.9	-0.9	-0.7	-0.3	-1.1	-0.5	-0.5	-1.2	-1.3	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.4	0.4	0.4	-0.4	-0.5	0.4	-0.9	-2.1	-0.1	0.5	0.4
Qualifications: CSEs or equivalent	0.6	0.8	1.0	-0.9	-0.9	-0.9	-0.6	-0.9	-1.0	-0.9	-0.9	-0.8	-0.9
Waist circumference	0.6	2.3	4.7	-2.1	-2.1	-0.8	0.6	-1.6	-1.1	0.4	-1.0	-2.2	-2.0
Worrier / anxious feelings	0.6	1.2	1.9	-1.2	-1.2	-1.0	-0.8	-1.3	-0.3	0.2	-1.4	-1.4	-1.2
Qualifications: A levels/AS levels or equivalent	0.6	1.2	4.4	-0.7	-0.7	-1.4	-2.1	-0.8	-1.8	-0.5	-0.2	0.5	-0.7
Emphysema/chronic bronchitis	0.6	0.7	2.0	-0.1	-0.1	1.0	1.4	-0.0	1.1	1.2	-0.2	-1.1	-0.1
Medication: Ibuprofen	0.6	0.7	1.8	-0.4	-0.5	0.5	0.7	-0.9	1.0	1.3	-1.0	-1.2	-0.5
Alcohol intake frequency.	0.6	1.3	2.5	-1.5	-1.5	-0.4	-0.3	-1.5	-0.4	0.5	-1.1	-1.6	-1.5
Medication: Aspirin	0.6	0.8	1.5	-1.2	-1.2	-0.3	-0.4	-0.8	-1.0	-0.6	-0.4	-1.0	-1.2
Arm fat mass (left)	0.6	2.5	6.1	-2.0	-2.0	-0.4	1.0	-1.6	-0.7	1.0	-1.1	-2.5	-2.0
Cholesterol lowering medication	0.6	0.9	1.7	-1.3	-1.3	-0.6	-0.9	-0.9	-1.3	0.3	-0.2	-0.2	-1.3
Intelligence (Savage-Jansen 2018)	0.5	1.7	3.2	-1.4	-1.3	-1.8	-1.8	-1.4	-1.5	-0.1	-0.8	-0.8	-1.2
Fasting Glucose	0.5	0.6	1.5	1.0	1.0	0.3	-0.2	0.7	0.1	-1.0	0.5	1.2	1.0
LDL Cholesterol	0.5	0.7	3.7	-0.2	-0.3	-0.8	-1.9	-0.3	-1.3	-0.6	-0.3	0.7	-0.3
Triglycerides	0.5	0.8	2.1	-0.9	-0.9	-0.5	-0.7	-1.2	-0.7	1.5	-0.5	-0.4	-0.9
Heel T-Score	0.5	3.8	18.4	-0.6	-0.6	-1.6	-2.6	-0.4	-3.0	-4.3	-0.5	0.1	-0.6
Systolic Blood Pressure	0.5	2.7	14.9	-0.5	-0.6	0.1	-1.8	-0.4	-2.5	-3.9	-0.1	1.1	-0.6
Relative age of first facial hair	0.5	1.1	2.0	1.4	1.4	0.6	0.3	1.3	0.5	-0.6	0.8	1.4	1.4
Diabetes (mother)	0.5	0.6	1.0	0.9	0.9	0.5	0.6	0.9	1.0	-0.5	0.8	0.7	0.9
Age when periods started (menarche)	0.5	1.1	3.0	1.4	1.4	0.5	-0.2	1.1	0.5	0.7	0.8	1.7	1.2
Hair/balding pattern: Pattern 2	0.5	0.6	1.4	-0.9	-1.0	-0.7	0.1	-0.5	-0.7	-0.5	-0.5	-1.2	-1.0
Pain all over the body in last month	0.5	0.5	1.3	-0.5	-0.5	0.7	0.9	-0.6	0.4	1.1	-0.2	-1.0	-0.5
Alcohol intake versus 10 years previously	0.5	0.8	1.3	0.9	0.8	1.1	1.1	0.7	1.1	0.9	0.7	0.5	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	3.0	0.0	0.0	0.9	1.6	-0.4	1.0	1.7	-0.0	-0.3	0.0
Illnesses of mother	0.5	0.6	1.6	0.6	0.6	1.1	1.0	0.3	1.3	1.1	0.3	0.5	0.5
Impedance of arm (left)	0.5	2.1	17.4	0.5	0.6	-0.2	-0.2	0.1	1.2	4.2	0.9	0.9	0.6
Arm fat mass (right)	0.5	2.1	5.3	-1.8	-1.8	-0.2	1.2	-1.5	-0.5	1.2	-1.0	-2.3	-1.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.7	-0.4	-0.4	-0.7	-1.5	-0.7	-1.6	-1.2	-0.1	0.2	-0.4
Blood clot in the leg (DVT)	0.5	0.6	1.5	1.0	1.0	0.2	0.3	1.2	0.0	-0.1	0.8	1.1	0.9
Worry too long after embarrassment	0.5	0.8	1.5	-0.8	-0.8	-0.7	-0.8	-1.0	-0.9	-1.1	-1.2	-0.7	-0.8
Heart disease (mother)	0.5	0.7	1.3	0.8	0.9	0.6	0.5	1.1	0.5	0.3	1.1	1.0	0.9
Family relationship satisfaction	0.5	0.6	1.1	0.6	0.6	0.9	1.1	0.6	0.8	0.8	0.9	0.7	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	-1.0	-1.0	-0.6	-0.3	-1.0	-0.4	0.1	-0.8	-0.9	-1.0
Illnesses of father: Heart disease	0.5	0.7	2.6	-0.5	-0.4	-1.0	-1.6	-0.2	-1.4	-1.0	-0.1	0.2	-0.4
Average weekly red wine intake	0.5	0.8	1.9	-0.7	-0.7	-0.3	-0.8	-0.9	-0.9	-1.4	-1.1	-0.7	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.4	-0.5	-0.6	-0.9	-0.9	-0.5	-0.7	-1.5	-0.9	-0.8	-0.7
Age started oral contraceptive pill	0.5	0.6	1.7	-0.4	-0.4	-1.1	-1.3	-0.5	-0.8	-0.9	-0.5	-0.4	-0.4
Diastolic blood pressure, automated reading	0.5	1.7	8.5	-1.2	-1.2	-0.0	-0.1	-0.7	-1.5	-2.9	-0.4	-1.0	-1.2
Basal cell carcinoma (self-reported)	0.5	0.6	3.7	0.4	0.5	-0.1	-0.3	0.2	-0.0	1.9	0.6	0.9	0.5
Heart disease (siblings)	0.5	0.7	1.1	0.7	0.7	0.9	0.9	1.0	-0.1	-0.8	1.1	0.7	0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	1.6	0.5	0.5	0.8	1.2	0.7	0.9	1.1	0.7	0.3	0.5
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.7	-1.1	-1.1	-1.1	-1.2	-1.0	-1.3	0.5	-0.2	-0.3	-1.0
Schizophrenia (2014)	0.4	0.8	2.2	0.8	0.8	0.3	0.0	0.8	0.4	1.2	1.2	1.5	0.8
Type 2 Diabetes (T2D) (2012)	0.4	0.4	3.1	-0.2	-0.3	0.4	0.3	-0.4	0.6	1.8	0.1	-0.0	-0.3
Cardiovascular Disease	0.4	1.2	3.1	-1.3	-1.3	0.2	-0.9	-1.0	-1.7	-1.3	0.2	0.2	-1.3
Lung FVC	0.4	2.0	11.8	-0.4	-0.3	-1.3	-1.0	-0.2	-0.6	-3.4	-1.6	-1.5	-0.3
Average weekly fortified wine intake	0.4	0.4	1.2	-0.5	-0.5	-0.8	-1.1	-0.2	-0.6	-1.0	-0.6	0.1	-0.4
Maternal smoking around birth	0.4	0.5	1.6	-0.8	-0.8	0.4	1.0	-0.7	-0.2	0.5	-0.3	-1.3	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	4.3	0.6	0.6	-0.7	-0.7	0.7	-1.3	-2.1	0.8	1.0	0.7
Trunk fat mass	0.4	1.9	6.4	-1.3	-1.3	0.4	1.8	-1.0	0.2	2.5	-0.2	-1.8	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.3	0.2	0.2	-1.0	-0.9	0.4	-1.4	-2.1	0.4	0.5	0.3
Financial difficulties in last 2 years	0.4	0.6	0.9	-0.8	-0.8	-1.0	-0.7	-1.0	-0.1	0.4	-0.9	-0.8	-0.8
Impedance of arm (right)	0.4	2.1	17.3	0.4	0.5	-0.4	-0.5	-0.1	1.0	4.2	0.8	0.9	0.5
Time employed in main current job	0.4	0.5	0.7	0.8	0.9	0.1	0.2	0.8	0.8	0.6	0.7	0.5	0.9
Hair/balding pattern: Pattern 3	0.4	0.6	1.1	0.8	0.8	1.1	0.9	0.4	0.9	0.8	0.9	0.5	0.7
Pulse rate	0.4	0.6	1.3	-1.0	-1.0	-0.0	-0.1	-1.1	-0.4	0.7	-0.4	-1.1	-1.0
Asthma	0.4	0.9	1.4	-1.0	-1.0	-1.1	-0.6	-1.2	-0.8	-0.5	-0.8	-0.9	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	-0.2	-0.3	0.6	1.0	-0.6	1.0	0.6	-1.0	-1.1	-0.3
Pulse wave reflection index	0.4	0.5	3.4	0.3	0.3	-0.6	-0.5	0.4	-0.2	-1.8	-0.0	0.1	0.3
Headache pain in last month	0.4	0.7	3.6	0.4	0.3	1.1	1.0	0.1	0.8	1.9	0.6	0.4	0.3
Birth weight	0.4	1.0	3.8	0.3	0.3	0.6	1.4	0.2	1.5	2.0	0.2	-0.9	0.3
Comparative body size at age 10	0.4	1.2	3.9	-1.3	-1.3	-0.4	-0.0	-1.3	-0.2	0.5	-1.2	-2.0	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.1	0.2	0.1	1.0	1.4	0.4	0.8	1.0	0.2	0.0	0.1
Health satisfaction	0.4	0.5	1.0	-0.9	-0.9	-0.2	0.0	-0.9	-0.3	0.3	-0.7	-1.0	-0.9
Whole body fat mass	0.4	1.8	4.3	-1.4	-1.5	0.3	1.8	-1.1	0.1	1.8	-0.5	-2.1	-1.4
Smoking status: Previous	0.4	0.6	1.2	-1.0	-1.0	-0.8	-0.2	-0.8	-0.6	-0.4	-0.8	-1.1	-0.9
Medication for cholesterol	0.4	0.7	1.3	-0.5	-0.5	-1.1	-0.5	-0.9	0.5	0.9	-1.1	-1.0	-0.5
Asthma (self-reported)	0.4	0.7	1.2	-0.9	-0.9	-1.1	-0.5	-1.1	-0.8	-0.6	-0.7	-0.8	-0.9
Number of operations (self-reported)	0.4	0.6	1.2	0.9	0.9	0.4	0.4	0.8	0.0	-1.1	0.7	0.8	1.0
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.0	0.9	1.0	0.0	0.1	0.7	0.8	-0.8	0.0	0.4	1.0
Unable to work because of sickness or disability	0.4	0.5	1.2	-0.8	-0.9	-0.3	0.2	-0.7	-0.2	1.1	-0.2	-0.8	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.2	0.9	0.8	0.0	0.1	1.1	0.0	-0.1	0.6	1.0	0.8
Neuroticism (Nagel 2018)	0.3	0.6	2.2	-0.5	-0.5	-1.1	-0.8	-0.4	-0.4	-1.5	-1.0	-0.6	-0.6
Schizophrenia (2018)	0.3	0.7	2.2	0.8	0.8	0.3	-0.2	0.8	0.6	0.8	1.1	1.5	0.8
Body Mass Index (BMI) (2010)	0.3	0.3	1.2	0.6	0.6	0.9	1.1	0.4	0.0	0.0	0.3	0.1	0.6
Mean Putamen Volume	0.3	0.4	0.9	0.6	0.7	1.0	0.5	0.2	0.5	0.7	0.3	0.5	0.7
HDL Cholesterol	0.3	0.4	2.2	0.7	0.6	-0.2	0.0	0.8	0.3	-1.5	0.1	0.2	0.6
Blood White Count	0.3	2.1	4.8	0.9	0.9	2.2	2.1	0.7	1.8	1.9	1.5	0.7	0.9
Waist Hip Ratio (WHR)	0.3	1.5	4.8	-0.9	-1.0	-1.6	-1.7	-1.0	-0.7	2.2	0.3	0.5	-1.0
Smoking Status	0.3	0.7	3.2	0.2	0.3	0.4	1.8	0.1	1.3	1.0	-0.0	-1.0	0.4
Respiratory disease	0.3	0.6	1.3	-0.8	-0.8	-0.8	-0.2	-1.1	-0.3	-0.3	-0.9	-0.9	-0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.2	-0.3	-0.4	-0.5	-0.2	-0.0	-0.8	-1.5	-0.2	-0.3	-0.3
Medication: Metformin	0.3	0.4	0.8	-0.9	-0.8	-0.6	-0.5	-0.7	-0.9	0.1	-0.2	-0.2	-0.8
Impedance of leg (left)	0.3	1.5	9.1	0.8	0.8	0.5	0.5	0.3	1.5	3.0	0.8	0.6	0.8
Number of incorrect matches in round	0.3	0.6	1.6	0.8	0.7	0.2	0.2	1.2	0.3	-1.2	0.5	0.6	0.7
Past tobacco smoking	0.3	0.5	1.6	0.8	0.8	0.3	-0.5	0.7	0.1	-0.3	0.7	1.2	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.1	-0.5	-0.5	-0.8	-0.0	-0.5	-0.0	-0.8	-0.9	-1.1	-0.6
Forced vital capacity (FVC)	0.3	1.1	2.3	1.4	1.5	0.2	-0.6	1.0	0.5	-1.1	0.3	1.1	1.5
Fluid intelligence score	0.3	0.7	1.4	-1.0	-1.0	-0.7	-1.0	-0.8	-1.2	-0.0	-0.1	-0.1	-0.9
Neuroticism score	0.3	0.7	1.8	-0.8	-0.8	-0.7	-0.2	-0.9	-0.2	-0.4	-1.3	-1.1	-0.9
Hip circumference	0.3	1.5	4.8	-1.3	-1.3	0.4	1.8	-1.0	-0.3	0.3	-0.7	-2.2	-1.3
Father’s age at death	0.3	0.4	0.7	0.8	0.8	0.1	0.4	0.8	0.6	-0.1	0.7	0.6	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.9	0.7	0.7	-0.1	-0.6	0.4	0.8	0.5	0.4	1.0	0.7
Mouth/teeth dental problems: Dentures	0.3	0.5	2.2	-0.7	-0.7	0.1	0.9	-0.6	0.3	0.1	-0.4	-1.5	-0.7
Tense / ‘highly strung’	0.3	0.5	2.7	-0.2	-0.3	-0.3	0.2	0.0	0.1	-1.7	-1.0	-0.8	-0.3
Age at first live birth	0.3	0.5	2.3	-0.1	-0.1	-0.9	-1.5	0.3	-0.7	-0.8	-0.1	0.6	-0.0
Medication: Omeprazole	0.3	0.3	1.3	0.1	0.1	0.5	1.0	-0.0	0.6	1.1	-0.2	-0.4	0.1
Overall health rating	0.3	0.6	1.3	-0.9	-1.0	-0.2	0.9	-0.9	-0.2	0.7	-0.3	-1.2	-0.9
Osteoarthritis (self-reported)	0.3	0.3	0.9	-0.4	-0.4	0.5	0.9	-0.5	0.4	0.7	-0.3	-1.0	-0.5
Guilty feelings	0.3	0.4	1.2	-0.4	-0.5	-0.9	-1.1	-0.6	-0.4	-0.3	-0.8	-0.0	-0.5
Ever taken oral contraceptive pill	0.3	0.3	1.2	-0.1	-0.1	0.9	1.1	-0.2	0.7	0.7	-0.1	-0.5	-0.1
High cholesterol (Self-reported)	0.3	0.6	1.9	-0.9	-0.9	-0.2	-0.5	-0.3	-1.4	0.9	0.6	0.4	-0.8
Average weekly beer plus cider intake	0.3	0.5	1.5	-0.4	-0.4	0.3	1.2	-0.1	0.6	1.2	-0.4	-0.8	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.0	-0.4	-0.4	0.2	1.0	-0.3	0.3	0.7	-0.5	-1.0	-0.4
Depression (Nagel 2018)	0.2	0.3	0.6	-0.5	-0.6	-0.4	-0.0	-0.4	-0.3	-0.6	-0.6	-0.8	-0.6
Worry (Nagel 2018)	0.2	0.4	2.7	-0.3	-0.4	-0.5	-0.4	0.2	0.1	-1.6	-0.5	-0.3	-0.4
Prostate Cancer	0.2	0.2	0.5	0.7	0.7	0.1	-0.0	0.4	0.6	0.6	0.3	0.3	0.7
Neuroticism (2016)	0.2	0.4	1.6	0.0	-0.5	-0.8	-0.8	-0.3	-1.3	0.0	-0.4	-0.4	0.0
BMI	0.2	0.9	4.5	-0.7	-0.7	1.1	2.1	-0.2	-0.2	-0.3	-0.0	-1.2	-0.7
Height	0.2	4.0	12.2	2.1	2.1	1.2	0.7	1.2	1.9	3.5	1.6	2.2	2.0
Hypothyroidism (self reported)	0.2	0.4	1.8	0.0	-0.0	-0.4	-0.8	0.3	-0.7	-1.3	0.5	0.9	0.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.3	0.3	0.3	0.8	0.7	0.3	0.4	1.1	0.7	0.8	0.3
Lung FEV1/FVC ratio	0.2	1.1	5.4	-0.9	-0.9	0.4	1.2	-0.7	-0.2	-0.5	-0.8	-2.3	-1.0
Hearing difficulty/problems: Yes	0.2	0.3	0.5	0.7	0.7	0.1	0.0	0.4	0.5	-0.7	0.2	0.3	0.7
Impedance of leg (right)	0.2	1.0	6.7	0.5	0.6	0.3	0.1	0.0	1.2	2.6	0.5	0.4	0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.3	0.3	0.9	0.6	0.3	0.4	0.6	0.4	0.4	0.2
Supplements: Glucosamine	0.2	0.2	1.4	-0.2	-0.1	0.1	0.8	-0.5	0.2	-0.2	-0.3	-1.2	-0.1
Medication: Levothyroxine sodium	0.2	0.3	1.7	-0.0	-0.1	-0.3	-0.3	0.5	-0.6	-1.3	0.6	0.4	-0.1
Nervous feelings	0.2	0.4	0.5	-0.6	-0.6	-0.7	-0.7	-0.5	-0.6	-0.5	-0.7	-0.3	-0.6
Medication: Simvastatin	0.2	0.2	0.9	0.2	0.2	0.3	0.2	0.4	-0.1	0.7	0.9	0.8	0.2
Number of live births	0.2	0.3	1.4	0.1	0.2	0.7	0.7	0.2	0.1	1.2	0.8	0.4	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.7	1.2	1.3	0.6	0.0	0.9	0.4	-1.2	0.3	0.8	1.3
Noisy workplace	0.2	0.2	1.5	-0.2	-0.2	-0.4	-0.4	-0.2	-0.4	-1.2	-0.2	-0.1	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.9	-0.5	-0.5	-0.2	-0.1	-0.7	-0.2	-0.5	-0.9	-0.7	-0.5
Loud music exposure frequency	0.2	0.2	1.3	-0.1	-0.1	0.5	0.8	-0.1	0.5	1.1	0.1	-0.4	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.9	0.1	0.0	0.6	0.9	0.1	0.6	0.6	0.1	0.0	0.0
Forced vital capacity (FVC), Best measure	0.2	0.6	1.6	1.0	1.1	-0.0	-0.7	0.6	0.2	-1.3	-0.0	0.6	1.1
Number of full brothers	0.2	0.3	0.9	-0.5	-0.6	-0.2	0.1	-0.6	-0.2	1.0	-0.4	-0.3	-0.6
Migraine (self-reported)	0.2	0.2	1.0	-0.3	-0.3	1.0	0.9	-0.3	-0.2	0.3	0.0	-0.2	-0.4
Had major operations	0.2	0.2	0.3	0.4	0.5	0.5	0.6	0.5	0.5	-0.5	0.4	0.1	0.5
Loneliness, isolation	0.2	0.2	1.1	0.2	0.1	0.3	0.9	-0.1	0.6	1.1	0.1	0.1	0.1
Diabetes diagnosed by doctor	0.2	0.4	1.4	-0.7	-0.6	-0.6	-0.7	-0.6	-1.2	0.4	0.0	0.3	-0.6
Friendships satisfaction	0.2	0.2	0.7	-0.3	-0.4	0.4	0.5	-0.6	0.3	0.8	-0.2	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	2.8	0.4	0.5	0.1	-0.1	0.5	0.6	-1.7	-0.3	-0.2	0.5
Average weekly champagne plus white wine intake	0.2	0.3	0.8	0.6	0.6	0.5	0.6	0.9	0.7	-0.2	0.3	0.4	0.6
Hearing aid user	0.2	0.2	1.4	-0.2	-0.2	0.7	1.2	-0.2	0.4	-0.1	-0.1	-0.4	-0.2
Illnesses of father: High blood pressure	0.2	0.2	0.9	-0.3	-0.3	-0.2	-1.0	-0.4	-0.6	0.6	-0.0	0.5	-0.4
Alcohol drinker status: Never	0.2	0.2	0.7	-0.4	-0.5	0.2	0.7	-0.4	0.4	0.2	-0.4	-0.8	-0.5
Ever smoked	0.2	0.4	1.4	-0.6	-0.6	-0.1	0.8	-0.6	0.0	0.2	-0.7	-1.2	-0.5
Fractured/broken bones in last 5 years	0.2	0.2	0.6	0.4	0.4	0.8	0.7	0.3	0.3	0.1	0.1	0.5	0.4
Ever depressed for a whole week	0.2	0.3	1.9	0.3	0.4	0.3	0.2	0.3	-0.3	-1.4	0.0	0.4	0.4
Bipolar Disorder or Schizophrenia	0.1	0.3	0.9	-0.5	-0.6	-0.8	-0.9	-0.4	-0.5	0.6	0.2	0.2	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.3	0.1	0.1	-0.5	-0.5	0.0	0.1	-0.1	-0.2	0.1	0.1
Ovarian Cancer	0.1	0.1	0.4	0.2	0.3	-0.4	-0.0	-0.1	-0.0	-0.7	-0.3	-0.3	0.3
Blood Eosinophil Count	0.1	1.1	5.9	-1.0	-1.0	-0.2	0.3	-1.1	0.4	2.4	-0.2	-1.0	-0.9
Blood Platelet Count	0.1	1.0	2.5	-0.9	-0.9	-1.4	-1.0	-1.0	-1.6	0.8	0.2	-0.3	-0.9
Allergy or Eczema	0.1	0.2	0.9	-0.3	-0.3	-0.0	1.0	0.1	-0.4	0.2	0.7	-0.5	-0.3
Hair Pigment	0.1	1.5	5.1	-1.3	-1.3	-0.7	0.8	-1.1	0.2	0.9	-1.1	-2.3	-1.4
Hand grip strength (left)	0.1	0.3	0.8	0.5	0.5	0.8	-0.1	0.4	-0.1	-0.9	0.1	0.5	0.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.7	0.3	0.2	0.2	0.1	0.3	-0.3	-0.2	0.5	0.8	0.3
Hand grip strength (right)	0.1	0.2	1.1	0.2	0.2	1.0	-0.1	-0.1	-0.5	-0.6	-0.3	0.3	0.1
Fed-up feelings	0.1	0.1	0.6	0.2	0.1	0.4	0.8	0.0	0.6	0.1	-0.2	-0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.7	0.1	0.1	-0.2	-0.8	0.0	-0.2	0.1	0.0	0.9	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.1	0.1	0.0	0.2	1.0	0.5	-0.1	0.6	1.1	-0.3	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.1	-0.1	-0.3	-0.4	-0.1	0.2	-0.4	-0.7	-0.3	-0.1
Sitting height	0.1	0.7	1.4	1.1	1.1	0.1	-0.4	0.8	0.3	-0.6	0.5	1.2	1.1
Qualifications: None of the above	0.1	0.3	1.6	-0.1	-0.0	-0.2	0.3	0.2	-0.3	-1.3	-0.4	-0.7	-0.0
Allergy	0.1	0.1	0.8	0.1	0.1	0.1	-0.9	-0.3	0.1	-0.0	-0.5	0.5	0.0
Diabetes (self-reported)	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.2	-0.0	-0.6	0.3	0.3	0.6	-0.0
Weight	0.1	0.7	2.4	-0.8	-0.9	0.6	1.6	-0.5	-0.1	0.8	-0.1	-1.2	-0.9
Trunk fat-free mass	0.1	0.4	1.3	0.5	0.4	0.8	0.6	0.6	-0.2	-1.2	0.5	0.5	0.5
Falls in the last year	0.1	0.1	0.6	-0.1	-0.1	-0.4	-0.2	-0.4	-0.4	0.8	0.1	0.5	-0.1
Depression (self-reported)	0.1	0.1	0.5	0.3	0.2	-0.2	-0.2	0.2	-0.0	0.2	0.2	0.7	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.5	0.7	0.7	0.2	-0.5	0.3	-0.2	-1.6	-0.2	0.2	0.7
Pulse wave Arterial Stiffness index	0.1	0.1	0.5	-0.0	0.0	-0.6	-0.7	-0.1	0.1	-0.3	-0.1	0.1	0.0
Trunk predicted mass	0.1	0.4	1.2	0.5	0.5	0.8	0.7	0.7	-0.1	-1.1	0.5	0.6	0.5
Breastfed as a baby	0.1	0.2	0.6	0.2	0.2	0.3	0.3	0.3	0.6	0.7	0.5	0.5	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.6	-0.1	-0.2	0.4	0.5	0.3	-0.7	-0.8	0.2	-0.2	-0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.3	-0.4	-0.4	-0.5	-0.4	-0.4	-0.1	-0.3	-0.6	-0.1	-0.4
Glaucoma (self-reported)	0.1	0.1	0.2	-0.3	-0.3	0.0	-0.3	-0.0	-0.5	0.2	0.2	-0.0	-0.3
Gout (self-reported)	0.1	0.2	0.4	0.2	0.1	0.4	0.5	0.5	0.7	-0.0	0.4	0.5	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.6	-0.1	-0.2	-0.5	-0.4	0.3	-0.6	-1.3	0.5	0.3	-0.2
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.4	0.1	0.1	0.6	0.6	0.0	-0.1	0.6	0.6	0.4	0.2
Arm fat-free mass (right)	0.1	0.6	2.0	0.4	0.4	1.2	1.4	0.6	0.1	-1.1	0.3	0.1	0.4
Exposure to tobacco smoke outside home	0.1	0.1	0.3	-0.3	-0.2	0.0	0.3	-0.3	0.2	0.6	-0.1	-0.4	-0.2
Pulse wave peak to peak time	0.1	0.1	0.4	0.2	0.1	0.7	0.6	0.2	-0.0	0.4	0.2	0.2	0.1
Neck or shoulder pain in last month	0.1	0.1	0.4	0.1	0.0	0.3	0.7	-0.0	0.2	0.4	-0.1	-0.2	-0.0
Arm predicted mass (right)	0.1	0.7	2.6	0.6	0.5	1.5	1.6	0.8	0.3	-0.8	0.5	0.3	0.5
Suffer from ‘nerves’	0.1	0.1	0.4	0.1	0.0	-0.1	0.2	0.4	0.5	-0.6	-0.4	-0.1	0.0
Chest pain or discomfort	0.1	0.2	0.3	-0.6	-0.5	-0.3	-0.4	-0.6	-0.3	-0.2	-0.5	-0.2	-0.5
Leg pain on walking	0.1	0.1	0.3	-0.2	-0.2	0.2	0.3	-0.1	-0.6	-0.3	-0.0	-0.2	-0.2
Illnesses of siblings: Diabetes	0.1	0.2	0.5	0.4	0.5	0.1	-0.1	0.0	-0.1	0.7	0.5	0.5	0.5
Mood swings	0.1	0.1	0.6	-0.1	-0.1	-0.4	0.1	-0.5	0.0	0.3	-0.8	-0.5	-0.1
Long-standing illness, disability or infirmity	0.1	0.1	0.4	-0.2	-0.2	0.1	0.3	-0.0	-0.5	-0.6	0.1	0.1	-0.2
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.4	0.4	0.0	0.2	0.5	0.3	-0.3	-0.2	0.4	0.4
Back pain experienced in last month	0.1	0.2	0.7	0.1	0.1	0.0	0.9	-0.2	0.1	0.5	-0.2	-0.7	0.2
Mineral and other dietary supplements	0.1	0.1	0.7	-0.1	-0.1	-0.0	-0.2	-0.4	0.6	0.8	-0.3	-0.1	-0.1
Osteoporosis (self-reported)	0.1	0.2	0.3	0.5	0.5	0.3	0.3	0.5	0.2	0.5	0.4	0.4	0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.2	0.2	0.1	0.4	0.1	0.4	-0.1	-0.4	-0.4	0.2
Commuting to job workplace: Public transport	0.1	0.1	0.2	0.0	-0.1	0.4	0.3	0.1	0.1	0.4	0.4	0.4	-0.0
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	-0.3	-0.3	-0.0	-0.3	-0.1	-0.5	-0.3	-0.1	0.2	-0.4
Arm fat-free mass (left)	0.1	0.3	1.1	-0.1	-0.2	0.7	1.1	0.1	-0.2	-0.8	-0.0	-0.4	-0.2
Arm predicted mass (left)	0.1	0.3	1.5	0.2	0.2	1.0	1.2	0.4	0.1	-0.7	0.2	-0.0	0.2
Depressed Affect (Nagel 2018)	0.0	0.1	0.2	0.4	0.3	-0.1	0.5	0.4	0.4	-0.4	0.1	0.0	0.3
Alzheimer’s Disease (in father)	0.0	0.0	0.3	0.2	0.1	0.2	0.6	0.0	0.1	0.0	0.0	0.0	0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.5	4.2	-0.2	-0.2	-0.3	-0.6	0.0	-0.5	-2.0	-0.3	-0.4	-0.2
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.3	0.0	-0.0	0.1	0.5	0.2	0.2	0.1	-0.1	-0.2	-0.0
Leg fat-free mass (left)	0.0	0.2	1.1	-0.3	-0.3	0.6	1.0	-0.1	-0.2	0.3	0.0	-0.3	-0.3
Relative age voice broke	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3	-0.1	-0.3	-0.1	0.2	-0.0	0.1
Leg predicted mass (left)	0.0	0.2	1.1	-0.3	-0.3	0.6	1.0	-0.1	-0.2	0.3	0.0	-0.3	-0.3
Hearing difficulty/problems with background noise	0.0	0.1	0.4	0.1	0.1	0.1	0.2	0.1	0.1	-0.6	-0.1	-0.2	0.1
Had menopause	0.0	0.0	0.0	0.0	0.0	-0.1	-0.1	-0.1	-0.2	-0.0	0.1	-0.1	0.0
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	-0.1	-0.1	-0.4	-0.5	0.1	-0.4	-0.6	-0.3	-0.1	-0.1
Medication: Allopurinol	0.0	0.0	0.1	-0.2	-0.2	0.0	-0.0	0.1	0.1	-0.4	-0.1	0.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	-0.1	-0.1	-0.3	0.0	-0.1	-0.1	-0.2	-0.2	-0.3	-0.1
Whole body fat-free mass	0.0	0.2	0.8	0.2	0.1	0.7	0.9	0.4	-0.2	-0.7	0.3	0.2	0.1
Leg fat-free mass (right)	0.0	0.2	1.5	0.0	-0.0	0.8	1.2	0.3	0.1	0.3	0.3	0.0	0.0
Whole body water mass	0.0	0.2	0.8	0.2	0.2	0.8	0.9	0.4	-0.1	-0.8	0.3	0.2	0.2
Leg predicted mass (right)	0.0	0.2	1.5	0.0	-0.0	0.8	1.2	0.3	0.0	0.3	0.3	0.0	-0.0
Basal metabolic rate	0.0	0.2	1.2	-0.1	-0.2	0.7	1.1	0.1	-0.1	-0.2	0.1	-0.2	-0.1
Alcohol drinker status: Previous	0.0	0.0	0.1	-0.2	-0.2	-0.3	-0.2	-0.1	-0.1	0.1	0.3	-0.1	-0.2

Hub : Genes

C20orf135

Models

Trait associations