TWAS hub - C21orf49

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0790	0.0310	2.5e-03	0.007	0.025	0.001	0.027	0.013	0.03800	4.4e-04	2.5e-01	2.6e-04	8.8e-03
2	METSIM	Adipose	0.1180	0.0307	1.1e-05	0.023	0.045	0.068	0.058	0.060	0.00019	2.7e-07	2.0e-10	4.3e-09	2.5e-09
3	TCGA	Bladder Urothelial Carcinoma	0.0620	0.0370	1.6e-03	0.020	0.034	0.033	NA	0.036	0.00710	6.5e-04	7.7e-04	NA	5.2e-04
4	TCGA	Breast Invasive Carcinoma	0.0332	0.0220	4.1e-04	0.003	0.008	0.012	NA	0.006	0.06600	7.4e-03	1.1e-03	NA	1.4e-02
5	TCGA	Cervical Squamous Cell Carcinoma	0.2920	0.1490	6.1e-04	0.017	0.073	0.072	NA	0.043	0.04700	1.9e-04	2.1e-04	NA	3.4e-03
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0521	0.0306	2.1e-03	0.030	0.032	0.017	NA	0.021	0.00024	1.6e-04	4.0e-03	NA	1.8e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0339	0.0214	5.7e-03	0.014	0.016	0.015	NA	0.014	0.00930	6.0e-03	6.3e-03	NA	9.2e-03
8	TCGA	Pancreatic Adenocarcinoma	0.1630	0.0920	1.6e-03	0.067	0.061	0.020	NA	0.053	0.00090	1.5e-03	4.9e-02	NA	2.9e-03
9	TCGA	Pheochromocytoma and Paraganglioma	0.0990	0.0610	8.4e-03	-0.007	0.003	0.006	NA	-0.007	0.82000	2.5e-01	1.8e-01	NA	9.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Time employed in main current job	5.2	6.0	10.6	-1.5	-1.6	-3.2	-1.4	-3.3	-3.0	-3.0	-2.6	-1.5
Medication: Co-codamol	5.0	5.8	9.0	-2.0	-2.0	-3.0	-2.7	-2.1	-3.0	-2.9	-2.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	4.3	6.9	11.8	-1.3	-2.2	-3.4	-3.4	-2.4	-3.3	-3.2	-2.1	-1.1
Major Depression (MDD)	3.8	4.6	9.6	-1.3	-1.4	-3.1	-1.6	-3.1	-2.3	-2.4	-2.2	-0.6
Pain all over the body in last month	3.2	3.4	5.4	-1.6	-0.9	-2.3	-1.8	-1.9	-1.9	-2.1	-1.7	-1.9
Financial situation satisfaction	2.8	3.4	7.0	-1.1	-0.9	-2.0	-2.4	-0.5	-1.8	-2.4	-2.6	-1.7
Eye problems/disorders: Glaucoma	2.6	3.0	6.0	-1.8	-0.9	-2.4	-1.0	-2.4	-2.4	-1.8	-1.0	0.2
Eye problems/disorders: None of the above	2.4	2.8	6.9	1.9	1.6	1.9	-0.6	2.6	2.1	1.3	1.4	0.3
Friendships satisfaction	2.3	2.8	6.7	-0.3	-0.1	-1.8	-1.8	-1.5	-1.2	-2.0	-2.0	-2.6
Bipolar Disorder (2018)	2.2	3.4	5.4	0.6	1.8	1.6	2.3	0.9	1.9	2.3	2.1	2.2
Qualifications: CSEs or equivalent	2.1	2.7	5.6	-2.4	-0.3	-1.7	-1.0	-1.9	-2.2	-1.7	-0.8	-1.6
Serious illness, injury or assault to yourself	2.1	2.6	5.6	-1.4	2.0	-1.5	-1.6	-1.2	-2.4	-1.6	-0.9	-1.3
Mouth/teeth dental problems	2.1	3.2	5.0	1.4	1.2	2.0	1.6	1.8	2.2	2.2	1.7	1.7
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	6.0	0.1	-1.2	-2.1	-2.5	-1.2	-1.9	-2.1	-1.5	-0.6
Medication: Ventolin 100micrograms inhaler	2.1	2.7	6.3	0.7	1.0	1.8	2.5	1.5	1.2	2.2	1.2	1.8
Arm fat percentage (right)	2.0	7.7	31.0	-5.6	-1.2	-2.2	-1.6	-2.3	-3.8	-2.2	-0.6	-2.3
Arm fat mass (right)	1.9	7.8	24.6	-5.0	-0.6	-2.6	-2.2	-2.5	-4.0	-2.5	-0.6	-2.2
Suffer from ‘nerves’	1.9	3.0	9.9	3.1	1.6	0.5	0.6	0.3	2.5	1.2	1.0	2.3
Waist circumference	1.8	6.5	15.0	-3.8	-0.0	-2.5	-1.6	-2.6	-3.9	-2.6	-1.0	-2.5
Osteoporosis (self-reported)	1.8	2.3	8.0	1.3	1.0	1.5	-0.2	2.8	1.8	1.4	1.2	0.7
Schizophrenia vs Biploar Disorder	1.7	2.2	7.7	-2.4	-2.0	-0.6	-2.8	0.7	-0.8	-0.8	0.6	-0.7
Relative age of first facial hair	1.7	3.4	5.5	1.0	1.0	2.3	1.8	2.1	2.1	2.4	1.8	1.8
Body mass index (BMI)	1.7	7.1	25.4	-5.0	0.4	-2.1	-1.7	-2.2	-4.0	-2.1	0.0	-2.3
Knee pain experienced in last month	1.7	2.6	8.3	0.6	2.9	1.9	1.0	1.7	1.0	1.6	1.7	1.0
Handedness (chirality/laterality): Left-handed	1.7	2.0	6.4	1.4	1.5	1.4	2.5	0.5	1.4	1.4	0.3	1.2
Arm fat mass (left)	1.7	7.1	23.9	-4.9	-0.6	-2.5	-2.0	-2.4	-3.8	-2.3	-0.4	-2.1
Vitamin and mineral supplements	1.6	2.2	4.9	1.4	0.9	1.0	0.8	1.0	2.2	1.7	1.4	2.2
Number of live births	1.6	2.2	5.4	-0.6	-0.2	2.2	0.9	2.3	1.7	1.9	1.4	-0.2
Qualifications: A levels/AS levels or equivalent	1.6	3.6	8.5	2.9	-2.3	1.5	1.9	0.9	2.1	1.8	1.1	1.9
Exposure to tobacco smoke at home	1.6	1.8	6.7	2.1	1.2	-0.6	0.4	-0.1	1.0	0.6	1.3	2.6
Arm fat percentage (left)	1.6	6.5	26.8	-5.2	-1.1	-1.9	-1.4	-2.1	-3.4	-1.9	-0.5	-2.1
Neuroticism (2016)	1.5	2.2	3.2	1.1	1.6	1.3	1.8	0.9	1.6	1.8	1.6	1.5
BMI	1.5	8.6	32.5	-5.7	-0.8	-2.3	-2.6	-1.7	-4.5	-2.3	0.2	-2.0
Leg fat mass (right)	1.5	5.7	13.7	-3.7	-0.6	-2.5	-1.6	-2.5	-3.7	-2.3	-0.7	-1.8
Ever taken oral contraceptive pill	1.5	1.7	6.5	-1.1	-2.5	-0.6	-0.7	-0.5	-1.2	-1.2	-1.1	-1.6
Hip circumference	1.4	5.9	16.9	-4.1	-0.4	-2.6	-2.3	-2.5	-3.0	-2.3	-0.5	-1.6
Happiness	1.4	1.7	4.0	-0.8	0.5	-1.2	-1.7	-0.2	-0.8	-1.6	-1.6	-2.0
Ever had bowel cancer screening	1.4	1.7	5.1	0.3	2.3	1.5	1.4	0.8	1.1	1.5	1.1	-0.5
Average weekly beer plus cider intake	1.4	2.1	8.9	-3.0	-1.5	-0.5	-1.7	0.1	-1.7	-0.8	0.2	-0.9
Age when periods started (menarche)	1.3	3.1	7.7	-1.0	-1.0	2.5	0.9	2.8	1.6	2.1	2.1	0.4
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	5.1	0.0	0.5	1.6	0.2	2.3	1.4	1.2	0.7	0.5
Impedance of leg (left)	1.3	6.4	13.1	3.6	-1.2	2.3	3.5	1.4	3.3	2.8	0.1	2.2
Neck or shoulder pain in last month	1.3	1.9	5.1	-0.9	1.5	1.4	-0.1	2.3	0.5	1.3	1.9	1.1
Medication: Omeprazole	1.3	1.6	3.2	-1.6	-0.3	-1.3	-1.3	-0.8	-1.8	-1.6	-1.1	-0.6
Whole body fat mass	1.3	5.6	17.2	-4.1	-0.5	-2.4	-1.6	-2.4	-3.4	-2.1	-0.5	-1.6
Family relationship satisfaction	1.3	1.6	2.5	-1.3	0.2	-1.3	-1.4	-0.6	-1.2	-1.5	-1.5	-1.6
Commuting to job workplace: Car/motor vehicle	1.3	1.4	3.1	-0.1	-1.8	-1.6	-1.3	-1.0	-1.5	-1.5	-0.4	-0.2
Hearing aid user	1.3	1.5	2.9	-0.8	-1.2	-1.5	-0.5	-1.7	-1.4	-1.3	-1.5	-0.5
Leg fat mass (left)	1.3	5.2	13.7	-3.7	-0.3	-2.4	-1.4	-2.4	-3.5	-2.1	-0.6	-1.6
Chronotype (morning person)	1.2	2.7	6.9	2.6	1.6	1.2	1.2	0.9	2.5	1.5	0.8	1.3
Impedance of leg (right)	1.2	5.7	12.2	3.5	-1.9	2.1	3.3	1.2	2.9	2.5	0.0	2.0
Maternal smoking around birth	1.2	1.7	3.6	-0.9	-0.7	1.7	0.8	1.9	0.7	1.5	1.7	1.1
Trunk fat mass	1.2	5.0	14.4	-3.8	-0.8	-2.3	-1.4	-2.4	-3.2	-2.1	-0.7	-1.5
Weight	1.2	6.0	12.7	-3.5	-0.1	-2.7	-2.2	-2.6	-3.6	-2.6	-0.5	-1.7
Worrier / anxious feelings	1.2	2.3	5.5	1.4	1.1	1.7	1.1	1.1	2.3	1.7	1.6	1.2
Mouth/teeth dental problems: Dentures	1.2	1.9	3.6	-1.9	1.7	1.4	1.0	1.2	1.1	1.4	1.8	0.4
Body fat percentage	1.2	4.9	18.1	-4.3	-1.1	-1.9	-0.9	-2.2	-3.1	-1.7	-0.6	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.1	-0.8	0.0	-1.6	-1.0	-1.1	-2.0	-1.6	-1.0	0.2
Mean Putamen Volume	1.1	1.2	3.4	1.3	1.8	1.4	1.6	0.8	0.4	0.9	0.1	-0.0
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.1	-2.0	-2.0	0.0	-1.5	0.9	-0.7	-0.5	0.1	-0.8
Trunk fat percentage	1.1	4.4	16.7	-4.1	-1.2	-1.8	-1.1	-2.0	-2.8	-1.7	-0.7	-1.6
Average weekly fortified wine intake	1.1	1.3	4.0	-2.0	-0.6	-1.2	-1.2	-1.2	-1.3	-1.2	-0.1	-0.6
High blood pressure (mother)	1.1	1.5	3.1	1.3	1.0	0.7	1.7	-0.1	1.5	1.3	0.8	1.8
Alcohol usually taken with meals	1.1	1.7	7.8	2.8	0.1	1.3	1.3	0.8	1.6	1.0	-0.1	0.1
Neuroticism score	1.1	2.2	5.7	1.0	1.1	1.3	1.2	0.8	2.4	1.8	1.8	1.2
Pulse rate	1.1	1.9	5.0	-0.5	-0.0	-1.7	-2.2	-0.5	-1.4	-1.9	-1.2	-1.2
Leg fat percentage (right)	1.1	4.1	10.9	-3.3	-0.9	-1.9	-0.2	-2.6	-3.2	-1.5	-0.7	-1.3
Worry too long after embarrassment	1.1	1.8	5.7	0.8	-0.1	0.4	-0.4	0.7	1.8	1.1	2.4	2.2
Shortness of breath walking on level ground	1.1	1.3	2.4	-1.6	0.0	-1.1	-1.5	-0.7	-1.4	-1.3	-0.7	-1.0
Age at last live birth	1.1	1.6	3.3	1.4	-1.2	1.6	1.8	0.9	1.5	1.0	-0.9	-0.5
Average weekly red wine intake	1.1	1.6	8.3	2.9	-0.1	0.3	1.2	-0.5	1.5	0.5	-0.4	1.3
Smoking status: Current	1.1	1.7	7.8	-2.8	-0.5	0.8	-0.9	1.8	-0.3	0.4	1.4	-0.1
Commuting to job workplace: Public transport	1.1	1.3	3.0	1.4	1.7	0.8	-0.5	1.3	0.8	0.9	1.2	0.8
Fractured/broken bones in last 5 years	1.1	1.4	3.7	-1.9	0.5	-1.1	-1.8	-0.4	-1.8	-1.1	-0.2	-0.4
Blood White Count	1.0	7.1	25.6	-2.3	-5.1	-2.6	-1.9	-1.7	-3.2	-2.3	-2.0	-0.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.3	0.7	0.1	1.0	-0.3	1.4	1.5	1.2	1.3	1.1
Stomach or abdominal pain in last month	1.0	1.3	2.8	0.9	-0.4	-1.3	-0.7	-1.7	-1.0	-1.3	-0.9	-1.3
Hair/balding pattern: Pattern 2	1.0	1.3	7.2	-1.3	-2.7	-0.1	-0.6	0.4	-0.5	-0.5	-0.8	-0.8
Medication: Lansoprazole	1.0	1.1	3.1	0.5	1.8	0.7	0.1	1.5	0.2	0.6	0.7	1.7
Pulse wave Arterial Stiffness index	1.0	1.2	2.3	0.5	-1.2	-1.5	-1.3	-1.1	-0.5	-1.4	-1.2	-0.1
Medication: Amlodipine	1.0	1.4	5.8	0.7	2.4	1.2	1.4	0.2	1.0	1.0	1.1	-0.1
Qualifications: College or University degree	1.0	3.0	12.2	3.5	-3.4	0.0	0.3	0.1	1.3	0.0	-1.2	0.8
Emphysema/chronic bronchitis	1.0	1.1	2.9	0.4	-0.1	1.7	1.6	0.8	1.1	1.2	0.3	-0.8
Diabetes diagnosed by doctor	1.0	1.6	4.3	-1.7	0.0	-1.1	-0.2	-1.7	-2.1	-1.2	-0.7	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	4.0	-1.0	-2.0	-0.6	-1.6	0.4	-0.4	-0.8	-0.6	-0.1
Medication: Gliclazide	1.0	1.1	4.6	0.3	0.5	-0.1	-0.3	0.2	-1.1	-0.9	-1.7	-2.1
Leg fat percentage (left)	1.0	3.6	11.4	-3.4	-0.4	-1.8	-0.0	-2.4	-2.9	-1.3	-0.5	-1.2
Worry (Nagel 2018)	0.9	1.9	5.3	2.3	2.0	0.5	0.8	0.3	2.2	0.9	0.5	1.1
Alzheimer’s Disease (in father)	0.9	1.0	2.2	-1.5	0.7	-0.8	-0.1	-1.1	-1.0	-0.8	-0.6	-1.4
Reaction Time	0.9	1.6	4.6	0.3	2.1	1.4	2.1	0.4	0.7	1.5	0.9	-0.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	6.7	-2.6	1.2	0.0	-1.2	1.0	-0.0	0.0	0.4	0.1
Supplements: Zinc	0.9	1.0	2.3	-0.8	-1.3	-1.3	-0.3	-1.5	-1.0	-0.8	-1.0	0.0
Leg fat-free mass (left)	0.9	5.0	11.1	-2.3	-0.1	-2.6	-3.3	-1.6	-3.1	-2.8	-0.5	-1.2
Current tobacco smoking	0.9	1.5	6.8	-2.6	-0.7	0.8	-0.7	1.7	-0.2	0.4	1.3	-0.2
Multivitamins +/- minerals	0.9	1.2	3.4	-0.7	-0.9	-0.9	-0.8	-0.8	-1.8	-1.3	-1.0	-0.9
Leg predicted mass (left)	0.9	5.0	11.5	-2.3	-0.1	-2.6	-3.4	-1.6	-3.1	-2.8	-0.4	-1.1
Financial difficulties in last 2 years	0.9	1.2	3.2	-1.8	-0.1	-0.3	-1.4	0.9	-1.6	-0.9	-0.3	-1.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	4.9	-1.1	0.2	0.2	-0.2	0.6	0.7	0.9	1.7	2.2
Blood clot in the leg (DVT)	0.9	1.2	2.3	-1.4	-0.5	-0.8	-1.5	0.4	-1.1	-1.2	-1.4	-0.9
Exposure to tobacco smoke outside home	0.9	1.2	2.7	-0.5	0.2	1.4	0.6	1.6	0.2	1.3	1.6	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	4.2	-0.9	2.0	0.6	0.4	-0.1	-0.2	0.2	0.2	-2.0
Guilty feelings	0.9	1.4	3.1	0.1	-0.1	1.5	1.3	0.6	1.6	1.5	1.8	0.4
Medication: Lisinopril	0.9	1.1	4.4	-2.1	0.2	0.9	0.8	0.4	0.5	1.0	1.7	0.3
Irritability	0.9	1.5	3.6	1.3	-1.1	0.6	1.8	-0.2	1.9	1.2	-0.1	1.4
Ever had prostate specific antigen (PSA) test	0.9	1.0	3.7	1.9	1.2	0.7	1.2	0.4	1.2	0.4	-0.7	-0.2
Alzheimer’s Disease (in mother)	0.8	0.9	2.2	0.1	1.1	1.1	1.0	0.6	0.5	1.1	1.5	0.9
Fasting Glucose	0.8	0.9	3.3	0.9	-1.8	-0.4	1.1	-0.9	0.7	0.5	0.2	1.2
LDL Cholesterol	0.8	1.2	3.3	0.1	-1.8	-0.8	-0.3	-0.8	-1.4	-1.1	-1.3	-1.1
Primary Biliary Cirrhosis	0.8	1.1	7.0	-2.6	-0.1	-0.4	-0.6	-0.0	-1.1	-0.5	-0.5	-0.7
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.2	-0.1	0.5	-1.3	-1.5	-1.0	-1.0	-1.1	0.1	-0.7
Hair/balding pattern: Pattern 3	0.8	1.2	8.8	1.0	3.0	0.3	0.7	-0.1	0.9	0.3	-0.1	0.0
Number of full brothers	0.8	1.0	2.6	-0.4	1.6	1.4	0.7	0.7	0.1	0.9	0.9	-1.4
Wheeze or whistling in the chest in last year	0.8	1.5	5.0	-1.9	-0.2	1.5	-0.1	2.2	-0.3	0.9	0.9	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.7	1.6	-1.0	-0.1	1.2	-0.6	0.8	-0.1	-1.6	0.1
Pulse wave peak to peak time	0.8	1.0	1.9	-0.4	1.2	1.4	1.1	1.0	0.5	1.2	1.2	0.0
Medication: Seretide 50 evohaler	0.8	0.9	2.6	-1.0	0.8	1.1	-0.4	1.6	0.7	0.8	1.2	-0.2
Pulse rate, automated reading	0.8	2.7	7.9	-1.4	0.6	-1.5	-2.8	-0.2	-2.2	-2.0	-0.8	-1.4
Alcohol intake frequency.	0.8	1.8	10.2	-1.8	3.2	-0.7	-0.8	-0.2	-0.8	-0.1	0.6	-0.1
Leg fat-free mass (right)	0.8	4.0	10.0	-2.2	0.4	-2.4	-3.2	-1.4	-2.6	-2.5	-0.3	-0.8
Mood swings	0.8	1.4	5.1	0.5	1.1	-0.0	0.9	-0.5	1.5	1.2	1.2	2.3
Long-standing illness, disability or infirmity	0.8	1.3	5.8	-1.2	2.4	0.6	-1.0	1.1	0.6	0.6	1.0	-0.2
Back pain experienced in last month	0.8	1.2	5.7	0.4	1.5	-0.4	-2.4	0.7	-0.7	-0.8	0.7	-0.4
Breast cancer (self-reported)	0.8	1.0	4.8	2.2	1.5	-0.5	-0.6	0.4	0.7	-0.3	-0.4	0.7
Illnesses of father: None of the above (group 1)	0.8	1.0	2.8	-0.3	-1.7	-0.9	0.6	-1.3	-0.9	-0.7	-1.3	-0.4
Leg predicted mass (right)	0.8	4.2	10.3	-2.2	0.3	-2.5	-3.2	-1.4	-2.7	-2.5	-0.3	-0.9
Number of self-reported non-cancer illnesses	0.8	1.4	8.5	0.2	2.9	0.6	1.4	0.3	0.5	0.9	0.5	0.8
Wears glasses or contact lenses	0.8	1.0	2.8	-0.0	1.7	1.4	1.6	0.7	-0.3	0.8	0.6	0.2
Arm fat-free mass (left)	0.8	3.9	9.2	-1.9	0.6	-2.6	-2.4	-1.9	-3.0	-2.3	-0.2	-0.8
Commuting to job workplace: Cycle	0.8	1.0	2.3	1.5	-0.8	1.0	1.5	0.5	0.8	0.7	-0.9	0.5
Impedance of whole body	0.8	4.1	8.5	2.5	-2.3	1.8	2.2	1.3	2.9	2.0	-0.5	1.5
Smoking Status	0.7	1.7	4.0	-1.9	-1.4	1.6	0.3	2.0	0.6	1.1	1.1	0.2
Average weekly spirits intake	0.7	0.8	3.9	-1.6	0.2	-0.2	0.3	0.0	-0.4	0.3	0.8	2.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.9	-2.0	-0.5	0.0	-0.6	0.5	-0.8	0.0	1.2	0.6
Angina	0.7	0.9	4.7	-2.2	0.6	-0.4	0.7	-1.3	-0.6	-0.2	0.2	-0.8
Hand grip strength (right)	0.7	1.8	13.6	3.7	1.0	-0.3	0.3	0.1	0.4	-0.2	-0.8	0.6
Relative age voice broke	0.7	1.1	4.4	-0.1	-0.7	0.5	1.3	0.1	1.0	1.2	0.5	2.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	6.0	1.1	2.4	-0.5	-0.5	0.2	0.0	-0.1	0.4	0.6
Medication: Ramipril	0.7	0.9	2.3	1.2	-0.1	-1.5	-0.0	-1.4	-0.4	-0.5	-0.4	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.3	1.2	0.5	-0.8	1.0	-0.8	-0.1	-0.1	-1.0	1.5
Medication: Cholesterol lowering	0.7	1.1	2.8	-0.0	-0.5	-1.3	-0.1	-1.7	-1.1	-1.1	-1.7	-0.6
Lung cancer (father)	0.7	0.8	1.6	1.2	-0.7	0.9	-0.0	1.1	1.2	0.8	1.0	0.5
Length of working week for main job	0.7	0.8	2.4	-0.1	1.1	0.8	1.6	0.5	-0.4	0.9	1.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.8	1.2	0.2	1.1	1.7	-0.2	0.8	1.1	1.5	0.6
Glaucoma (self-reported)	0.7	0.8	1.7	-0.7	0.2	-1.3	-1.1	-1.1	-1.2	-0.9	-0.4	0.7
Chronic bronchitis/emphysema (mother)	0.7	0.9	3.7	-1.9	-0.5	0.4	-1.1	1.0	-0.3	0.2	1.1	-0.4
Comparative body size at age 10	0.7	2.1	6.0	-1.8	0.5	-1.4	0.2	-2.5	-1.4	-1.4	-1.4	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	4.0	-0.4	2.0	0.5	1.4	-0.3	-0.1	0.5	-0.5	0.2
Number of full sisters	0.7	0.8	3.1	-1.4	1.2	0.5	0.3	-0.3	-0.5	0.1	0.3	-1.8
Loneliness, isolation	0.7	0.9	2.8	-0.3	1.2	0.6	0.1	1.3	0.4	1.0	1.7	0.8
Osteoarthritis (self-reported)	0.7	0.8	2.7	-1.6	0.8	1.0	-0.4	1.1	0.3	0.5	1.2	-0.1
Miserableness	0.7	1.1	2.1	1.4	0.4	0.7	0.8	0.7	1.4	1.2	1.0	1.5
Alcohol drinker status: Never	0.7	0.8	2.3	-1.5	1.2	-1.1	0.0	-1.3	-0.5	-0.2	0.2	0.7
Basal metabolic rate	0.7	3.9	8.2	-1.9	0.3	-2.6	-2.5	-2.0	-2.9	-2.4	-0.3	-0.8
Ever depressed for a whole week	0.7	0.9	1.9	0.9	1.4	-1.0	-0.4	-0.7	-1.3	-1.1	-1.0	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.9	-1.4	-0.4	-0.4	-1.3	0.8	-0.8	-0.9	-1.2	-0.8
Arm predicted mass (left)	0.7	3.7	9.1	-1.7	0.6	-2.6	-2.1	-2.2	-3.0	-2.2	-0.1	-0.8
Coronary Artery Disease (CAD)	0.6	0.8	2.0	0.3	1.2	0.7	1.4	-0.1	1.2	0.9	-0.0	0.7
Systolic Blood Pressure	0.6	2.8	8.6	2.3	2.9	-0.5	2.4	-1.6	0.1	0.2	-1.2	1.0
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.8	1.5	-0.3	-1.9	-0.9	-1.4	-1.0	-1.6	-1.6	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.8	0.9	0.8	-0.4	-1.7	0.2	-0.8	-1.0	-0.5	-0.4
Breastfed as a baby	0.6	0.7	2.4	-1.1	-1.2	-0.2	-1.5	0.5	-0.3	-0.8	0.1	-0.7
Tense / ‘highly strung’	0.6	1.0	2.8	1.0	0.1	0.7	1.1	0.2	1.7	1.3	1.2	1.0
Peak expiratory flow (PEF)	0.6	1.3	4.3	2.1	1.5	-0.9	-0.9	0.4	-0.4	-0.6	-0.5	1.7
Pulse wave reflection index	0.6	0.8	2.3	-0.5	-1.5	0.5	-0.4	1.2	0.6	0.7	0.8	1.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.4	-1.5	0.9	0.2	1.2	-0.4	-0.5	0.1	-0.5	-0.8
Loud music exposure frequency	0.6	0.7	1.9	0.4	0.3	-1.2	-0.1	-1.4	-0.8	-0.9	-0.9	0.6
Headache pain in last month	0.6	1.1	2.2	-0.4	1.1	-1.3	-1.0	-1.4	-1.5	-1.1	-0.6	-0.6
Angina (self-reported)	0.6	0.8	4.2	-2.1	0.7	-0.3	0.5	-1.1	-0.5	-0.2	0.1	-1.0
Mean time to correctly identify matches	0.6	1.1	4.0	-0.4	2.0	1.1	1.8	0.1	0.3	1.0	0.5	-0.3
Comparative height size at age 10	0.6	3.3	5.7	2.4	-0.1	-2.4	-1.7	-1.5	-1.5	-2.4	-2.2	-0.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.6	0.2	-1.2	1.2	0.4	0.7	1.3	0.9	0.5	-0.5
Medication: Aspirin	0.6	0.8	3.3	-0.7	1.0	0.5	1.8	-0.8	-0.1	0.5	-0.2	-1.1
Illnesses of siblings: Diabetes	0.6	0.8	2.5	-0.5	0.0	0.1	1.3	-0.6	0.1	1.0	1.1	1.6
Smoking status: Previous	0.6	0.9	3.6	1.1	-0.3	0.6	1.9	-0.5	1.1	0.8	-0.2	0.8
Asthma (self-reported)	0.6	1.3	2.8	-0.8	-0.1	1.5	0.4	1.6	0.9	1.4	1.7	-0.1
Medication: Aspirin	0.6	0.7	2.0	-1.2	0.4	0.1	1.0	-0.8	-0.7	-0.2	-0.8	-1.4
Whole body water mass	0.6	3.3	6.6	-1.4	0.4	-2.5	-2.6	-1.8	-2.6	-2.3	-0.2	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.9	-0.8	0.8	1.4	1.3	0.5	0.1	0.9	0.8	-0.6
Illnesses of father: High blood pressure	0.6	0.8	3.0	1.7	-0.4	-0.1	1.2	-0.8	0.7	0.5	0.1	1.1
Diastolic blood pressure, automated reading	0.6	1.8	5.5	-1.2	-0.2	-1.7	0.4	-2.3	-2.0	-1.2	-1.0	-0.6
Myopia	0.6	0.8	3.1	1.5	0.8	-0.1	-1.8	0.9	0.7	-0.3	-0.3	0.1
Vascular/heart problems diagnosed by doctor	0.6	1.6	6.2	1.4	-2.5	0.6	-1.0	1.7	1.1	0.1	-1.0	-0.2
Pain experienced in last month	0.6	0.9	4.2	-0.2	-2.0	0.5	1.1	0.3	1.1	0.9	-0.2	0.7
Depression (Nagel 2018)	0.5	0.7	2.5	-0.3	-0.2	-0.9	0.0	-1.6	-0.7	-0.8	-0.2	-1.2
Intelligence (Savage-Jansen 2018)	0.5	1.5	4.8	1.6	-2.2	-1.0	-0.5	-0.4	0.8	-0.2	-0.6	2.0
Schizophrenia (2018)	0.5	1.0	3.2	-0.2	-0.3	-1.8	-0.8	-1.6	-0.9	-1.3	-0.7	-0.1
Verbal and Numeric Reasoning (VNR)	0.5	1.3	3.8	1.8	-2.0	-0.6	-0.2	-0.3	1.0	0.1	-0.3	1.7
Breast Cancer	0.5	1.3	2.8	-0.3	0.1	1.1	-0.0	1.7	0.8	1.3	1.6	1.6
Triglycerides	0.5	0.7	2.1	-1.2	-1.2	-0.6	-1.5	-0.1	-0.8	-0.6	0.1	-0.3
Neuroticism	0.5	1.1	3.0	1.1	1.3	0.7	1.0	0.2	1.7	1.1	1.1	0.6
Hand grip strength (left)	0.5	1.3	10.5	3.2	0.3	-0.7	-0.4	-0.1	-0.1	-0.5	-0.5	0.5
Systolic blood pressure, automated reading	0.5	1.4	2.9	-0.6	1.6	-0.8	1.6	-1.7	-1.4	-0.6	-1.2	-0.2
Medication: Metformin	0.5	0.7	2.6	-0.4	-0.8	-0.9	-0.3	-1.0	-1.6	-0.9	-0.2	-0.5
Diabetes (mother)	0.5	0.7	1.9	-1.4	0.6	-0.1	1.1	-1.0	-0.2	0.5	1.1	-0.0
Severe depression (siblings)	0.5	0.5	1.9	-0.4	-0.3	-0.3	-0.4	-0.2	-0.8	-0.8	-1.0	-1.4
Pack years adult smoking proportion	0.5	0.8	2.0	-0.8	-1.4	0.2	-1.1	0.9	-0.6	-0.3	0.5	-1.3
Townsend deprivation index at recruitment	0.5	0.7	2.8	-1.7	1.3	0.1	-0.8	0.8	-0.3	0.1	0.7	0.1
Fed-up feelings	0.5	0.9	1.7	-0.6	-0.1	-0.9	-1.1	-0.1	-1.3	-1.2	-1.3	-0.9
Taking other prescription medications	0.5	0.8	4.7	-0.8	2.2	0.7	0.4	0.8	0.2	0.6	0.2	0.3
High blood pressure	0.5	1.5	6.4	-0.7	2.5	-0.8	1.1	-1.8	-1.1	-0.3	0.4	0.2
Supplements: Glucosamine	0.5	0.7	2.5	1.1	-0.3	0.7	0.2	0.8	1.6	0.7	0.5	0.6
Chronic bronchitis/emphysema (father)	0.5	0.5	1.5	-1.1	-1.2	-0.3	-1.2	0.4	-0.2	-0.2	0.7	0.3
Number of incorrect matches in round	0.5	0.8	2.9	0.5	0.7	-1.4	-0.8	-1.7	-0.2	-0.9	-0.7	0.3
Forced vital capacity (FVC)	0.5	1.7	3.5	1.3	-0.7	-1.9	-0.9	-1.3	-0.6	-1.4	-1.7	1.5
Diabetes (self-reported)	0.5	0.7	2.6	-1.6	0.3	-0.4	0.1	-1.1	-1.4	-0.4	0.4	-0.7
Fluid intelligence score	0.5	1.1	4.2	1.7	-2.1	-0.7	-0.8	-0.4	0.6	-0.3	-0.4	0.9
Asthma	0.5	1.1	2.8	-0.8	-0.2	1.4	0.1	1.7	0.6	1.2	1.5	-0.4
Prospective memory result	0.5	0.6	1.4	0.2	-0.0	0.8	-0.3	1.0	1.2	0.7	1.1	0.4
Illnesses of mother	0.5	0.6	2.3	-0.5	0.1	-0.5	-1.0	-0.3	-0.8	-0.9	-0.6	-1.5
Impedance of arm (left)	0.5	2.4	8.4	1.0	-2.9	1.3	0.6	1.3	2.5	1.1	-0.6	0.9
Age at first live birth	0.5	0.9	3.0	1.7	-1.2	0.6	0.7	0.1	0.7	-0.0	-1.2	-0.9
Health satisfaction	0.5	0.7	3.2	-0.6	1.8	-0.2	-0.2	-0.2	-0.7	-0.5	-0.5	-1.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	3.2	1.8	-0.4	0.3	0.7	0.2	0.6	0.4	-0.1	0.8
Migraine (self-reported)	0.5	0.6	2.2	-0.4	-1.3	-0.7	-1.5	-0.2	-0.6	-0.7	-0.3	-0.3
Medication: Ibuprofen	0.5	0.6	1.6	1.2	1.0	-0.1	-1.2	0.2	-0.5	-0.8	-0.6	-0.7
Overall health rating	0.5	1.0	3.7	-1.9	1.8	0.3	-0.8	0.9	-0.4	0.2	0.7	-0.5
Hypertension (Self-reported)	0.5	1.5	6.6	-0.7	2.6	-0.9	0.8	-1.8	-1.2	-0.5	0.3	0.3
Whole body fat-free mass	0.5	2.9	5.8	-1.2	0.5	-2.3	-2.4	-1.6	-2.4	-2.1	-0.2	-0.4
Eye problems/disorders: Cataract	0.5	0.5	1.3	-0.7	0.0	-0.3	1.0	-1.1	-1.0	-0.4	-0.5	-0.7
Medication: Bendroflumethiazide	0.5	0.7	1.2	-0.9	0.8	-0.9	-0.5	-0.9	-1.1	-0.8	-0.9	-0.7
Medication: Atorvastatin	0.5	0.7	1.7	-1.3	-0.5	-0.8	-0.8	-0.9	-0.5	-0.7	-0.6	-0.9
Supplements: Calcium	0.5	0.6	3.1	0.4	0.0	-0.2	-1.8	1.1	0.4	-0.2	0.8	0.1
Heart disease (siblings)	0.5	0.6	1.7	1.0	0.0	0.4	-0.0	0.7	1.3	0.8	0.5	1.1
Alcohol drinker status: Previous	0.5	0.6	1.6	-0.1	0.5	0.9	0.2	0.7	1.2	1.0	1.3	0.1
Neuroticism (Nagel 2018)	0.4	1.0	2.4	1.5	1.4	0.1	0.8	-0.2	1.4	0.6	0.4	1.1
Alzheimer’s Disease (including proxy)	0.4	0.6	2.6	0.0	1.6	0.7	0.8	0.3	0.5	0.7	0.8	-0.0
Irritable Bowel Disease (IBD)	0.4	1.0	3.0	-0.6	0.2	-1.6	-1.7	-0.8	-0.6	-1.1	0.5	0.7
Ulcerative Colitis (UC)	0.4	0.7	2.2	-0.7	-0.5	-1.0	-1.5	0.1	-0.2	-0.5	1.0	1.1
Bipolar Disorder (2011)	0.4	0.4	0.8	0.5	-0.9	-0.1	0.7	-0.1	0.9	0.5	0.4	0.8
Crohns Disease (2012)	0.4	0.6	2.3	1.5	1.5	0.0	0.6	-0.2	0.3	0.1	0.3	0.4
HbA1C	0.4	0.5	0.9	0.4	0.7	0.8	0.8	0.8	1.0	0.7	0.1	0.1
HDL Cholesterol	0.4	0.7	2.8	0.4	-0.4	-0.3	1.3	-1.0	-0.3	-0.3	-1.7	-0.4
Schizophrenia (2014)	0.4	0.9	2.0	-0.6	-0.7	-1.3	-1.4	-0.8	-0.7	-1.3	-0.7	-0.7
Blood Eosinophil Count	0.4	2.7	14.7	-3.8	-3.0	0.0	-0.6	0.1	0.2	0.2	0.7	-0.2
Medication for hormone replacement therapy	0.4	0.4	2.3	1.5	-0.2	0.1	-0.7	0.9	-0.1	-0.2	-0.4	-0.0
Diabetes (father)	0.4	0.5	1.5	-0.3	0.9	0.0	-0.9	0.3	-0.8	-0.7	-0.4	-1.2
Past tobacco smoking	0.4	0.7	2.1	-0.0	0.6	-0.7	-1.5	-0.1	-1.0	-0.9	-0.3	-1.1
Nervous feelings	0.4	0.8	2.2	0.5	1.2	0.8	-0.8	1.0	1.5	0.4	0.9	-0.2
Had menopause	0.4	0.5	1.3	-1.1	0.5	0.7	0.2	0.8	0.9	0.6	0.5	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.4	0.7	1.6	0.5	-0.5	0.6	0.4	0.2	0.5	-0.8
Falls in the last year	0.4	0.5	1.5	-0.2	0.4	-1.2	-0.4	-1.2	-0.5	-0.6	-0.8	0.4
Depression (self-reported)	0.4	0.4	1.3	-0.5	-0.0	0.3	-0.8	1.2	1.0	0.4	0.0	0.7
Trunk predicted mass	0.4	2.1	4.5	-0.6	0.4	-2.1	-2.0	-1.6	-1.9	-1.8	-0.0	-0.1
Birth weight of first child	0.4	0.8	3.0	1.7	0.9	1.0	0.4	1.2	0.1	0.6	0.4	0.4
Gout (self-reported)	0.4	0.5	2.2	-0.6	-1.5	0.2	0.9	-0.3	-0.9	-0.0	-0.3	0.2
Birth weight	0.4	0.8	1.9	0.1	0.9	-1.1	-0.2	-1.4	-0.9	-1.0	-0.9	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.5	-1.2	0.8	-0.0	-1.1	0.9	-0.2	-0.2	0.1	-0.5
Medication: Blood pressure	0.4	0.6	2.5	-0.1	1.6	-0.3	1.3	-1.1	-0.1	0.2	0.2	0.3
Medication: Allopurinol	0.4	0.5	1.9	-1.0	-1.4	-0.3	0.5	-0.6	-1.0	-0.3	-0.4	0.4
Arm predicted mass (right)	0.4	2.1	4.4	-0.8	0.8	-2.1	-1.8	-1.6	-2.1	-1.7	0.3	-0.1
Had major operations	0.4	0.4	2.6	1.6	0.8	-0.1	0.3	-0.2	0.5	-0.2	-0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.5	-0.2	-1.1	-0.8	-1.6	-0.3	0.0	-0.4	1.2	1.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.6	0.5	1.6	0.6	0.5	0.3	-0.9	0.1	0.6	0.2
Risk taking	0.4	0.6	1.7	0.2	-1.3	-1.1	-0.1	-0.8	-0.7	-0.7	-0.8	0.5
Age started oral contraceptive pill	0.4	0.4	1.9	-0.6	0.2	0.9	-0.2	1.4	0.6	0.4	0.2	-0.5
Basal cell carcinoma (self-reported)	0.4	0.4	1.3	0.7	0.1	-0.6	-0.0	-0.5	-1.2	-0.8	-0.8	-0.4
Pack years of smoking	0.4	0.6	1.4	-0.5	-1.1	0.5	-0.8	1.2	-0.4	-0.1	0.5	-1.2
Ovarian Cancer	0.3	0.4	1.0	0.5	0.8	0.1	-1.0	1.0	0.4	0.1	0.8	-0.0
Prostate Cancer	0.3	0.5	1.3	1.1	-1.1	0.3	-0.2	0.8	-0.1	-0.1	-0.9	0.2
Body Mass Index (BMI) (2010)	0.3	0.4	1.1	0.2	0.4	0.4	0.6	0.0	0.6	0.8	0.9	1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.7	-0.2	0.9	0.7	0.3	0.6	0.7	0.6	0.6	0.4
Waist Hip Ratio (WHR)	0.3	1.4	4.1	1.2	0.1	-0.5	1.2	-0.9	-1.5	-0.9	-2.0	-1.0
Cardiovascular Disease	0.3	1.0	5.7	0.2	2.4	-0.7	0.7	-1.0	-0.7	-0.2	0.4	1.0
Hypothyroidism (self reported)	0.3	0.8	2.0	0.3	1.4	0.7	1.0	0.7	-0.0	0.9	0.4	1.3
Respiratory disease	0.3	0.7	1.9	0.1	-0.8	0.9	-0.5	1.4	0.8	0.7	1.1	-0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.0	-1.0	0.3	-0.6	0.0	-0.9	-1.4	-0.6	-0.6	-0.5
Number of treatments/medications taken	0.3	0.5	2.0	-0.5	1.4	-0.3	0.8	-0.6	-0.5	-0.0	-0.4	0.6
Ever had hysterectomy (womb removed)	0.3	0.4	1.8	-0.7	-1.3	0.4	-0.0	0.0	0.6	0.2	-0.2	-0.7
Medication: Atenolol	0.3	0.4	2.4	-0.6	-0.3	0.1	0.5	-0.6	-0.2	-0.1	-0.1	-1.6
Sitting height	0.3	1.8	7.6	2.8	0.4	-1.6	-0.6	-1.3	-0.2	-1.0	-0.7	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.5	1.6	0.3	0.3	0.7	0.0	0.4	0.2	-0.1	0.4
Hearing difficulty/problems with background noise	0.3	0.5	2.3	-0.8	-0.0	0.4	-0.1	0.6	-0.5	-0.0	-0.6	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	3.3	1.0	0.5	-0.5	-0.7	-0.3	0.5	0.3	1.2	1.8
Qualifications: None of the above	0.3	0.7	2.6	-1.5	1.6	-0.0	0.1	-0.3	-0.6	0.2	0.8	-0.3
Heart attack	0.3	0.4	1.5	-1.1	-0.2	0.1	-0.4	0.2	0.3	0.3	1.2	0.5
Impedance of arm (right)	0.3	1.6	8.1	0.1	-2.8	0.8	0.3	0.7	1.9	0.7	-0.9	0.4
Trunk fat-free mass	0.3	2.0	4.3	-0.6	0.4	-2.1	-1.9	-1.6	-1.9	-1.8	-0.0	-0.0
Father’s age at death	0.3	0.5	2.3	0.0	-0.2	-0.4	-1.5	0.6	-0.6	-0.8	-0.4	-0.4
Noisy workplace	0.3	0.4	1.2	-0.3	0.6	-0.9	0.2	-1.1	-0.6	-0.3	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.1	1.1	0.1	-1.4	-0.2	-1.2	-0.7	-1.1	-1.2	1.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.6	-0.2	-1.1	0.2	-1.3	1.1	0.4	0.0	0.6	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.8	0.7	1.3	0.0	1.0	-0.2	0.2	0.4	-0.2	1.3
High blood pressure (siblings)	0.3	0.4	1.1	0.5	1.1	-0.8	-0.3	-1.1	-0.0	-0.3	-0.2	0.5
Arm fat-free mass (right)	0.3	1.7	3.5	-0.3	1.1	-1.9	-1.7	-1.3	-1.8	-1.5	0.3	-0.0
Medication for pain relief, constipation, heartburn	0.3	0.5	2.5	0.6	-1.6	-0.1	0.5	-0.3	0.9	0.1	-0.3	-0.1
Heart disease (mother)	0.3	0.4	1.4	-0.7	0.1	-0.7	0.5	-1.2	-0.8	-0.6	-0.4	-0.2
Leg pain on walking	0.3	0.4	1.8	-1.0	1.3	0.2	0.7	-0.2	-0.4	0.2	0.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.5	1.0	0.1	0.7	0.1	1.2	0.0	0.3	0.1	0.3
Illnesses of father: Heart disease	0.3	0.4	1.1	0.9	0.5	0.0	-0.5	0.6	0.7	0.4	0.6	1.0
Qualifications: nursing, teaching	0.3	0.4	1.7	-0.3	-1.3	0.6	-0.1	0.5	0.5	0.4	0.7	-0.5
Commuting to job workplace: Walk	0.3	0.3	0.5	0.1	-0.7	-0.6	-0.4	-0.6	-0.3	-0.7	-0.6	-0.6
Average weekly champagne plus white wine intake	0.3	0.4	1.8	0.8	-0.1	0.5	0.3	-0.1	0.5	-0.0	-0.3	-1.4
Mother’s age at death	0.3	0.4	1.3	-0.7	-0.3	-0.3	0.7	-1.1	-0.6	-0.2	-0.1	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.4	2.7	0.7	0.2	-0.5	-0.3	-0.1	0.2	0.0	0.1	1.6
Medication: Paracetamol	0.3	0.5	1.7	-0.3	1.3	-0.8	-0.0	-0.8	-0.6	-0.1	-0.1	0.9
Unable to work because of sickness or disability	0.3	0.4	1.3	-0.8	1.1	0.6	0.6	0.5	-0.3	0.4	0.1	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.5	-1.2	-0.2	-0.0	-0.5	0.2	0.1	0.2	1.1	0.6
Bipolar Disorder or Schizophrenia	0.2	0.5	1.7	0.3	0.8	-0.4	0.8	-0.7	0.5	0.5	0.8	1.3
Depressed Affect (Nagel 2018)	0.2	0.4	2.0	0.5	1.4	-0.5	-0.2	-0.3	0.4	-0.0	0.3	0.7
Crohns Disease (2017)	0.2	0.5	1.2	0.3	1.1	-1.0	-0.6	-0.6	-0.2	-0.5	0.5	0.9
Lupus	0.2	0.3	1.6	1.3	0.2	-0.0	0.2	-0.2	1.0	0.3	0.2	0.4
Rheumatoid Arthritis	0.2	0.2	0.9	-0.2	0.9	0.0	-1.0	0.4	-0.2	-0.2	0.4	-0.2
Ulcerative Colitis	0.2	0.3	0.7	-0.8	-0.0	-0.8	-0.7	-0.4	-0.3	-0.5	0.4	0.1
Blood Red Count	0.2	2.0	5.5	1.3	1.9	0.7	0.4	1.3	1.0	1.2	1.5	2.4
Allergy or Eczema	0.2	0.5	1.2	-1.1	1.0	0.5	-0.5	0.3	-0.0	0.2	1.0	-0.8
Lung FEV1/FVC ratio	0.2	0.9	3.2	-1.3	1.1	-0.4	-0.9	0.4	-1.8	-0.9	-0.1	0.0
Sensitivity / hurt feelings	0.2	0.3	1.0	0.0	0.6	0.5	1.0	-0.2	0.6	0.6	0.6	-0.0
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.8	-0.7	-0.3	-0.7	-0.5	-0.9	-0.1	-0.4	0.6	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.6	-0.3	0.7	-0.1	-0.1	-0.2	0.2	0.5	1.3	1.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.2	-0.9	0.4	0.7	0.1	0.5	0.4	0.7	1.1	0.0
Medication: Simvastatin	0.2	0.3	1.3	0.3	0.2	-0.8	0.4	-1.2	-0.3	-0.3	-0.6	0.1
Illnesses of siblings	0.2	0.2	0.7	0.4	-0.6	0.2	-0.1	0.7	-0.3	-0.4	-0.8	-0.5
Alcohol intake versus 10 years previously	0.2	0.3	0.7	0.5	0.3	-0.8	-0.0	-0.6	-0.4	-0.3	-0.5	0.7
Standing height	0.2	1.6	5.9	2.4	-1.1	-1.4	-1.1	-0.9	0.3	-1.1	-1.1	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.8	0.4	0.9	-0.7	-0.3	-0.7	-0.1	-0.4	0.1	0.5
Hair/balding pattern: Pattern 4	0.2	0.5	1.8	-1.3	-0.7	0.3	-0.8	0.5	-0.2	0.3	0.8	-0.5
Medication: Paracetamol	0.2	0.3	0.9	-0.5	0.9	-0.5	-0.0	-0.5	-0.6	0.2	0.3	0.9
Forced vital capacity (FVC), Best measure	0.2	0.9	1.7	0.9	-0.5	-1.3	-0.2	-1.0	-0.4	-0.9	-1.3	1.3
Number of children fathered	0.2	0.2	0.9	-0.3	0.3	0.1	-0.5	-0.2	0.2	-0.4	0.5	-0.9
Supplements: Vitamin C	0.2	0.2	0.8	-0.3	-0.9	0.0	0.9	-0.4	0.5	0.3	-0.1	-0.2
Mineral and other dietary supplements	0.2	0.3	1.0	0.3	-0.9	-0.5	0.2	-0.7	0.2	0.1	0.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.9	0.7	0.2	-0.3	-0.0	-0.1	0.2	0.3	0.9	1.7
Medication: Blood pressure	0.2	0.4	2.7	-1.6	-0.0	-0.4	-0.3	-0.5	-0.5	-0.2	0.3	-0.1
Ever smoked	0.2	0.3	0.8	-0.2	-0.6	0.7	0.9	0.3	0.5	0.5	0.1	0.2
Number of operations (self-reported)	0.2	0.4	1.8	1.3	-0.0	-0.3	-0.4	0.0	0.1	-0.5	-0.9	-0.5
Cholesterol lowering medication	0.2	0.3	1.2	-0.3	0.2	-0.1	0.3	-0.1	0.2	0.5	0.8	1.1
Age at First Birth	0.1	0.2	1.0	0.4	0.1	-0.3	-0.1	-0.2	1.0	0.0	-0.6	-0.1
Heel T-Score	0.1	0.7	3.4	-0.3	1.8	0.4	0.4	0.2	0.6	0.7	1.1	0.6
Height	0.1	1.9	6.3	2.5	0.3	-1.5	-0.4	-1.3	0.4	-0.7	-0.6	2.3
Lung FVC	0.1	0.6	3.4	-0.5	0.0	-0.0	1.0	-0.4	0.3	0.4	0.1	1.8
Hearing difficulty/problems: Yes	0.1	0.2	0.5	0.4	0.3	-0.2	0.7	-0.5	-0.5	-0.2	-0.5	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.8	-0.9	0.0	0.2	0.5	-0.4	-0.0	0.3	0.6	-0.4
Medication: Levothyroxine sodium	0.1	0.2	1.1	0.1	1.1	0.2	0.2	0.2	0.3	0.3	0.1	0.9
Had other major operations	0.1	0.2	0.5	0.1	0.7	-0.3	0.5	-0.4	0.2	0.2	-0.2	0.7
Allergy	0.1	0.3	0.7	0.8	0.4	-0.5	-0.2	-0.2	-0.3	-0.5	-0.6	0.6
Chest pain or discomfort	0.1	0.2	0.8	-0.4	-0.9	-0.5	-0.1	-0.4	0.2	0.2	0.4	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.7	-0.3	0.0	-0.2	-0.5	0.1	-0.3	-0.0	0.3	0.9
Medication for cholesterol	0.1	0.2	0.9	0.4	0.0	0.4	0.9	-0.5	0.5	0.2	-0.2	-0.4
High cholesterol (Self-reported)	0.1	0.2	1.1	0.6	-0.2	-0.6	0.0	-1.0	-0.1	-0.2	-0.4	0.3
Blood Platelet Count	0.0	0.6	2.6	1.6	0.3	-0.3	0.2	-1.1	0.2	-0.8	-0.4	0.0
Hair Pigment	0.0	0.7	2.6	0.4	0.5	1.0	-0.9	0.8	0.8	0.4	0.3	-1.6
Tanning	0.0	0.3	0.9	1.0	-0.6	0.5	0.8	0.2	0.4	0.3	0.1	-0.0

Hub : Genes

C21orf49

Models

Trait associations