TWAS hub - C22orf45

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.1016	0.0452	1.8e-06	0.033	0.052	0.039	NA	0.059	0.00011	1.5e-06	2.8e-05	NA	3.4e-07
2	TCGA	Prostate Adenocarcinoma	0.0921	0.0471	1.6e-04	0.015	0.046	0.034	NA	0.039	0.00900	1.3e-05	1.6e-04	NA	5.7e-05
3	TCGA	Thyroid Carcinoma	0.0770	0.0580	9.7e-03	0.018	-0.003	0.010	NA	0.002	0.00610	8.2e-01	3.1e-02	NA	2.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Chronic bronchitis/emphysema (mother)	8.8	10.3	13.8	3.7	3.3	2.5
Medication: Co-codamol	5.5	6.4	10.6	-3.3	-2.3	-1.8
Fractured/broken bones in last 5 years	5.2	6.8	10.0	-3.0	-1.1	-3.2
Blood Eosinophil Count	4.8	36.6	72.8	-5.4	-2.8	-8.5
Tinnitus: Yes, now most or all of the time	4.2	4.9	6.3	-2.5	-1.5	-2.5
Peak expiratory flow (PEF)	3.9	9.0	15.4	-3.2	-1.2	-3.9
Heart attack	3.6	4.6	7.4	-2.3	-2.7	-1.2
Worry too long after embarrassment	3.6	6.1	9.9	2.7	3.1	1.0
Heart attack/myocardial infarction (self-reported)	3.6	4.6	6.7	-2.4	-2.6	-1.3
Respiratory disease	3.4	7.5	13.7	-2.7	-1.2	-3.7
Age at first live birth	3.2	5.6	10.2	2.5	0.5	3.2
Medication: Paracetamol	3.1	5.2	9.6	-2.3	-3.1	0.9
Ever had hysterectomy (womb removed)	2.9	3.3	4.3	-2.1	-1.8	-1.6
Blood White Count	2.8	20.7	29.3	-3.6	-4.4	-5.4
Miserableness	2.8	4.8	11.2	-1.8	-0.0	-3.3
Medication: Paracetamol	2.6	4.1	7.6	-1.9	-2.8	0.9
LDL Cholesterol	2.5	4.0	6.7	-2.2	-0.6	-2.6
Medication: Ventolin 100micrograms inhaler	2.4	3.1	7.0	-1.6	0.1	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	5.5	-1.8	-0.7	-2.4
Number of full sisters	2.4	2.9	5.1	-1.6	-2.3	-1.0
Depressed Affect (Nagel 2018)	2.3	4.9	11.6	-1.7	-0.4	-3.4
Fed-up feelings	2.2	3.9	6.7	-2.2	-0.6	-2.6
Alcohol usually taken with meals	2.2	3.5	4.7	-2.0	-1.3	-2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.5	4.2	-1.2	-2.1	-1.4
Multivitamins +/- minerals	2.1	2.6	4.3	1.5	1.1	2.1
Wheeze or whistling in the chest in last year	2.1	3.7	4.8	-2.2	-1.3	-2.1
Qualifications: CSEs or equivalent	2.0	2.7	3.4	-1.8	-1.7	-1.3
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	4.5	1.5	1.0	2.1
Gout (self-reported)	2.0	2.8	6.1	1.0	2.5	-1.1
Supplements: Vitamin C	2.0	2.4	3.9	-2.0	-1.7	0.6
Supplements: Zinc	1.9	2.1	2.6	1.5	1.2	1.6
Taking other prescription medications	1.9	2.9	5.1	-2.3	-0.9	-1.7
Mouth/teeth dental problems: Loose teeth	1.9	2.3	3.3	1.6	1.8	0.9
Leg pain on walking	1.9	2.4	4.1	1.7	2.0	0.6
Long-standing illness, disability or infirmity	1.9	2.9	4.6	-2.2	-1.8	-0.9
Qualifications: College or University degree	1.8	5.8	10.6	2.3	1.3	3.3
Had major operations	1.8	2.1	5.1	-1.1	0.2	-2.3
Financial difficulties in last 2 years	1.7	2.2	2.6	-1.6	-1.6	-1.3
Birth weight of first child	1.7	3.1	4.3	2.1	1.4	1.7
Health satisfaction	1.7	2.1	4.1	1.5	2.0	0.4
Crohns Disease (2017)	1.6	3.6	4.7	-2.2	-1.8	-1.7
Lung FEV1/FVC ratio	1.6	8.1	8.3	-2.9	-2.9	-2.8
Sensitivity / hurt feelings	1.6	2.7	6.2	1.4	2.5	-0.1
Vitamin and mineral supplements	1.6	2.2	6.2	-0.6	-0.2	-2.5
Alcohol intake frequency.	1.6	3.7	5.1	-1.4	-2.0	-2.3
Worrier / anxious feelings	1.5	2.8	6.8	0.8	2.6	-1.0
Asthma (self-reported)	1.5	2.9	6.6	-1.5	0.0	-2.6
Neuroticism (Nagel 2018)	1.4	3.3	5.9	0.3	2.0	-2.4
Fasting Glucose	1.4	1.7	2.1	-1.3	-1.1	-1.4
Neuroticism (2016)	1.4	2.1	4.6	1.3	2.1	-0.2
Neuroticism	1.4	3.4	5.5	0.4	2.1	-2.3
Serious illness, injury or assault to yourself	1.4	1.6	2.8	1.3	0.6	1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	6.4	-1.7	-2.5	-0.7
Asthma	1.4	2.7	5.8	-1.5	-0.2	-2.4
Qualifications: nursing, teaching	1.4	2.1	4.8	1.2	0.4	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	3.2	1.3	1.8	0.6
Medication: Ramipril	1.3	1.7	3.8	-0.9	-2.0	0.7
Depression (self-reported)	1.3	1.6	3.7	1.0	1.9	0.2
Worry (Nagel 2018)	1.2	2.5	4.1	0.0	2.0	-1.8
Lupus	1.2	1.8	2.6	1.4	0.8	1.6
Hearing difficulty/problems: Yes	1.2	1.8	4.3	0.9	2.1	-0.5
Relative age voice broke	1.2	1.8	4.2	-1.1	0.4	-2.0
Medication: Atenolol	1.2	1.5	2.8	-1.0	-1.7	-0.9
Hearing difficulty/problems with background noise	1.2	1.9	4.9	-0.1	2.2	-0.9
Neuroticism score	1.2	2.6	4.5	0.3	2.1	-1.8
Illnesses of mother	1.2	1.5	3.1	-0.7	0.9	-1.8
Medication for pain relief, constipation, heartburn	1.2	2.0	3.1	1.6	1.8	0.7
Medication: Allopurinol	1.2	1.6	2.8	0.1	1.4	-1.7
Ovarian Cancer	1.1	1.4	2.8	-1.1	-0.5	-1.7
Ulcerative Colitis	1.1	1.6	2.8	1.7	0.7	1.2
Mouth/teeth dental problems	1.1	1.7	4.0	-0.9	-0.6	-2.0
Tense / ‘highly strung’	1.1	1.8	4.6	0.8	2.2	-0.1
Family relationship satisfaction	1.1	1.3	2.1	-1.2	-0.5	-1.5
Eye problems/disorders: Cataract	1.1	1.3	2.1	1.0	1.5	0.9
Guilty feelings	1.1	1.7	2.5	0.7	1.6	-1.4
Wears glasses or contact lenses	1.1	1.2	2.9	-0.9	0.1	-1.7
Hayfever, allergic rhinitis or eczema	1.0	2.2	3.0	1.1	1.6	1.7
Happiness	1.0	1.2	1.7	-1.3	-0.9	-1.0
Medication: Lansoprazole	1.0	1.1	2.7	-0.7	0.3	-1.6
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	3.0	-1.7	-1.6	-0.7
Number of children fathered	1.0	1.1	2.3	-0.8	0.7	-1.5
Medication for cholesterol	1.0	1.5	2.3	1.4	1.5	0.5
Osteoporosis (self-reported)	1.0	1.2	2.7	-0.9	0.5	-1.6
Osteoarthritis (self-reported)	1.0	1.3	2.4	-1.5	-0.8	-0.9
High cholesterol (Self-reported)	1.0	1.7	2.9	-1.3	-0.7	-1.7
Alcohol drinker status: Never	1.0	1.2	1.8	-1.1	-1.3	-0.9
Irritability	1.0	1.8	4.2	0.8	2.0	0.6
Cholesterol lowering medication	1.0	1.4	3.2	-1.0	-0.2	-1.8
Heart disease (siblings)	1.0	1.2	3.4	-0.3	-1.9	0.3
Alzheimer’s Disease (in father)	0.9	1.0	1.5	-0.9	0.7	-1.2
Blood Platelet Count	0.9	10.4	11.9	-3.0	-3.2	-3.5
Hypothyroidism (self reported)	0.9	2.2	3.0	-1.5	-1.7	-1.1
Number of treatments/medications taken	0.9	1.5	2.6	-1.6	-1.1	-0.9
Average weekly fortified wine intake	0.9	1.1	1.8	1.1	0.5	1.3
Age when periods started (menarche)	0.9	2.2	3.4	1.8	0.2	1.8
Pain all over the body in last month	0.9	1.0	2.8	0.1	1.7	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.4	0.8	1.5	0.4
Medication: Cholesterol lowering	0.9	1.3	3.7	0.2	0.6	-1.9
Glaucoma (self-reported)	0.9	1.0	1.8	-1.3	-1.1	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.6	-0.9	-1.6	0.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.4	-0.4	0.7	-1.5
Angina	0.8	1.0	2.1	-0.7	-0.7	-1.4
Pack years adult smoking proportion	0.8	1.2	1.3	-1.1	-1.2	-1.1
Maternal smoking around birth	0.8	1.2	2.1	1.1	1.4	0.7
Nervous feelings	0.8	1.5	4.0	0.4	2.0	-0.6
Qualifications: None of the above	0.8	1.6	4.3	-0.3	0.7	-2.1
Time employed in main current job	0.8	1.0	1.7	-0.0	-1.1	1.3
Mouth/teeth dental problems: Dentures	0.8	1.4	3.5	0.8	0.0	1.9
Exposure to tobacco smoke at home	0.8	0.9	1.1	-1.0	-0.8	-1.1
Hair/balding pattern: Pattern 4	0.8	1.9	2.7	1.4	0.9	1.7
Basal cell carcinoma (self-reported)	0.8	0.9	2.1	0.1	1.5	-0.8
Bipolar Disorder (2018)	0.7	1.0	2.5	-0.7	-1.6	0.4
Bipolar Disorder or Schizophrenia	0.7	1.6	3.2	-1.3	-1.8	-0.3
Crohns Disease (2012)	0.7	1.1	1.4	-1.2	-1.1	-0.8
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.1	-0.4	-0.7	-1.8
Diabetes (father)	0.7	0.8	1.2	0.5	1.0	1.1
Stomach or abdominal pain in last month	0.7	0.9	1.2	-1.1	-0.5	-1.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.3	-0.5	-1.5	-0.1
Medication: Simvastatin	0.7	1.0	2.8	-0.1	0.4	-1.7
Medication: Aspirin	0.7	0.9	1.9	-0.9	-0.4	-1.4
Supplements: Fish oil (including cod liver oil)	0.7	1.0	2.1	-0.3	-1.5	0.8
Irritable Bowel Disease (IBD)	0.6	1.3	2.0	-1.1	-1.4	-0.9
Prostate Cancer	0.6	0.9	2.2	-0.7	-0.1	-1.5
Age at First Birth	0.6	0.9	1.9	0.9	0.2	1.4
Primary Biliary Cirrhosis	0.6	0.9	1.5	-0.4	1.0	-1.2
Relative age of first facial hair	0.6	1.3	2.2	-0.4	1.5	-1.3
Medication: Metformin	0.6	0.8	1.4	0.4	0.9	-1.2
Hand grip strength (right)	0.6	1.7	4.3	0.9	0.2	2.1
Diabetes (self-reported)	0.6	0.9	2.4	-0.6	-0.1	-1.6
Qualifications: A levels/AS levels or equivalent	0.6	1.4	1.7	1.1	1.1	1.3
Prospective memory result	0.6	0.8	1.7	-0.4	0.6	-1.3
Lung cancer (father)	0.6	0.7	1.0	-1.0	-0.6	-0.8
Loud music exposure frequency	0.6	0.6	1.1	-0.3	0.8	-1.0
Birth weight	0.6	1.4	1.5	1.2	1.2	1.1
Leg fat percentage (right)	0.6	2.2	4.7	-0.9	-2.2	1.0
Shortness of breath walking on level ground	0.6	0.7	1.3	-0.9	-1.1	-0.2
Angina (self-reported)	0.6	0.8	1.5	-0.7	-0.7	-1.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.4	0.2	1.2	-0.8
Illnesses of father: None of the above (group 1)	0.6	0.7	2.0	-0.4	-1.4	0.0
Financial situation satisfaction	0.6	0.8	1.4	0.9	1.2	0.3
Medication: Atorvastatin	0.6	0.8	1.9	0.4	1.4	-0.6
Coronary Artery Disease (CAD)	0.5	0.6	0.8	-0.9	-0.4	-0.9
Mean Putamen Volume	0.5	0.5	1.0	-1.0	-0.5	-0.5
Rheumatoid Arthritis	0.5	0.6	1.0	-0.3	1.0	-0.9
Heel T-Score	0.5	3.9	8.7	1.5	-0.8	3.0
Allergy or Eczema	0.5	1.2	2.4	0.8	0.8	1.6
Hand grip strength (left)	0.5	1.4	3.9	0.6	-0.0	2.0
Average weekly spirits intake	0.5	0.6	1.2	0.3	1.1	-0.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	0.9	-0.2	-0.8	-0.9
Medication: Levothyroxine sodium	0.5	0.9	1.2	-1.1	-0.9	-0.8
Chronic bronchitis/emphysema (father)	0.5	0.5	1.1	0.7	-0.1	1.1
Impedance of leg (left)	0.5	2.2	5.7	0.9	-0.3	2.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.5	-0.1	-0.8	1.2
Alcohol intake versus 10 years previously	0.5	0.8	2.0	-0.5	0.4	-1.4
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	2.9	-1.7	-1.0	-0.8
Noisy workplace	0.5	0.6	1.0	1.0	0.4	0.9
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.0	-0.1	-0.7	1.4
Medication: Amlodipine	0.5	0.7	1.8	0.2	1.3	-0.4
Neck or shoulder pain in last month	0.5	0.7	1.5	-0.4	-1.2	0.6
Migraine (self-reported)	0.5	0.6	1.4	-0.4	1.2	-0.7
Heart disease (mother)	0.5	0.7	1.0	-0.2	-1.0	1.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	2.6	-0.1	1.6	-0.0
Mineral and other dietary supplements	0.5	0.6	1.8	-0.2	-0.1	-1.4
Number of self-reported non-cancer illnesses	0.5	0.9	2.0	-1.4	-0.9	-0.2
Leg fat percentage (left)	0.5	1.8	3.3	-0.3	-1.8	1.5
Age started oral contraceptive pill	0.5	0.6	1.3	0.7	1.1	0.2
Commuting to job workplace: Cycle	0.5	0.6	0.8	0.8	0.5	0.9
Schizophrenia (2018)	0.4	0.9	1.1	-1.1	-1.0	-0.7
Major Depression (MDD)	0.4	0.5	1.2	-0.4	0.1	-1.1
Reaction Time	0.4	0.7	1.5	-1.2	-0.8	-0.3
Schizophrenia (2014)	0.4	0.8	1.0	-0.9	-1.0	-0.8
Triglycerides	0.4	0.7	0.9	-0.8	-0.8	-1.0
Lung FVC	0.4	2.1	4.3	0.7	1.2	2.1
Chronotype (morning person)	0.4	0.9	2.5	0.1	0.6	-1.6
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.3	-0.6	-0.0	-1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.5	0.6	0.7	0.7
Sitting height	0.4	2.6	4.5	-1.8	-0.1	-2.1
Waist circumference	0.4	1.3	2.4	-1.2	-1.6	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.3	-0.6	0.5	-1.1
Trunk fat-free mass	0.4	2.1	2.8	-1.7	-1.4	-1.3
Father’s age at death	0.4	0.5	1.4	0.2	-0.3	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	1.8	-1.4	-0.8	-1.0
Trunk predicted mass	0.4	2.2	3.0	-1.7	-1.4	-1.3
Breastfed as a baby	0.4	0.4	0.9	-0.7	0.1	-0.9
Eye problems/disorders: None of the above	0.4	0.5	0.7	-0.3	-0.8	-0.8
Emphysema/chronic bronchitis	0.4	0.5	0.8	0.1	0.9	0.7
Suffer from ‘nerves’	0.4	0.6	1.7	0.0	1.3	-0.4
Illnesses of siblings: Diabetes	0.4	0.5	0.7	0.8	0.9	-0.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	-0.4	0.1	-1.1
Diabetes diagnosed by doctor	0.4	0.6	1.9	-0.0	0.0	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.3	0.1	-0.1	1.1
Breast cancer (self-reported)	0.4	0.4	0.7	0.6	-0.4	0.9
Pain type(s) experienced in last month: Hip pain	0.4	0.6	1.3	-0.2	1.1	-0.6
Ever smoked	0.4	0.8	1.8	0.2	-0.7	1.3
Unable to work because of sickness or disability	0.4	0.6	0.8	-0.9	-0.5	-0.9
Pack years of smoking	0.4	0.5	1.2	-0.5	-0.4	-1.1
Alzheimer’s Disease (in mother)	0.3	0.4	0.8	-0.4	-0.9	0.5
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.1	-0.5	-1.0	0.8
Medication for hormone replacement therapy	0.3	0.4	0.8	-0.4	-0.9	-0.2
Severe depression (siblings)	0.3	0.3	0.8	0.9	-0.1	0.5
Leg fat-free mass (left)	0.3	1.5	1.9	-1.4	-0.8	-1.4
Townsend deprivation index at recruitment	0.3	0.4	0.8	0.8	0.9	-0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.4	0.5	0.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.4	-0.7	-1.2	-0.1
Supplements: Glucosamine	0.3	0.5	1.3	-0.1	1.1	0.3
High blood pressure (mother)	0.3	0.4	0.6	0.8	-0.3	0.7
Hair/balding pattern: Pattern 2	0.3	0.4	0.6	-0.7	-0.7	0.2
Fluid intelligence score	0.3	0.7	1.2	-0.9	-1.1	0.3
Hip circumference	0.3	1.2	1.6	-1.3	-1.2	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.6	0.6	0.8	0.6
Pulse wave reflection index	0.3	0.4	0.7	-0.6	-0.5	-0.8
Headache pain in last month	0.3	0.4	1.1	-0.2	-1.0	0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.6	-0.7	-0.6	0.6
High blood pressure (siblings)	0.3	0.5	0.8	-0.3	-0.9	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.4	0.6	0.6	0.3
Medication: Omeprazole	0.3	0.3	0.6	-0.8	-0.4	-0.5
Mean time to correctly identify matches	0.3	0.6	1.0	-0.8	-0.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.8	0.9	0.3	-0.3
Leg fat mass (right)	0.3	1.2	2.5	-0.6	-1.6	0.8
Comparative height size at age 10	0.3	1.5	3.7	-0.9	-0.2	-1.9
Age at last live birth	0.3	0.5	0.8	0.7	0.1	0.9
Knee pain experienced in last month	0.3	0.4	1.0	-0.2	-0.5	1.0
Illnesses of father: Heart disease	0.3	0.5	0.8	0.9	-0.1	0.8
Average weekly red wine intake	0.3	0.5	1.3	-1.2	-0.2	0.3
Mood swings	0.3	0.5	1.5	-0.1	0.2	-1.2
Loneliness, isolation	0.3	0.4	0.8	0.1	0.6	-0.9
Ever had bowel cancer screening	0.3	0.4	0.6	0.0	0.8	-0.7
Medication: Aspirin	0.3	0.4	0.9	-0.5	-0.0	-1.0
Average weekly champagne plus white wine intake	0.3	0.4	0.6	0.3	0.8	-0.6
Hearing aid user	0.3	0.3	0.7	-0.5	-0.8	0.2
Mother’s age at death	0.3	0.3	0.6	0.8	0.3	0.6
Medication: Lisinopril	0.3	0.4	0.7	0.8	0.6	-0.4
Basal metabolic rate	0.3	1.5	2.0	-1.4	-1.2	-1.0
Number of operations (self-reported)	0.3	0.4	0.6	-0.4	0.8	-0.5
Average weekly beer plus cider intake	0.3	0.4	0.8	0.3	0.9	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.7	-0.5	-0.1	-0.8
Ever depressed for a whole week	0.3	0.3	0.8	-0.3	0.4	-0.9
Supplements: Calcium	0.3	0.3	0.6	0.3	0.8	0.4
Alcohol drinker status: Previous	0.3	0.3	0.6	0.3	-0.5	0.8
Leg fat mass (left)	0.3	1.0	2.3	-0.5	-1.5	0.8
Depression (Nagel 2018)	0.2	0.2	0.6	0.1	0.3	-0.8
Alzheimer’s Disease (including proxy)	0.2	0.2	0.7	-0.8	-0.2	-0.1
Breast Cancer	0.2	0.5	1.2	-0.3	-0.2	1.1
Bipolar Disorder (2011)	0.2	0.2	0.4	0.7	0.3	0.4
HDL Cholesterol	0.2	0.4	0.6	0.4	-0.7	0.8
Systolic blood pressure, automated reading	0.2	0.5	0.7	0.8	-0.4	0.8
Diabetes (mother)	0.2	0.3	0.4	0.6	0.6	0.4
Impedance of leg (right)	0.2	1.1	2.8	0.1	-0.8	1.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.1	-0.6	0.6
High blood pressure	0.2	0.7	1.2	0.8	0.5	1.1
Leg predicted mass (left)	0.2	1.3	1.8	-1.3	-0.8	-1.3
Had menopause	0.2	0.3	0.6	0.1	0.5	-0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.3	0.5	0.5	0.5
Allergy	0.2	0.6	1.6	0.1	-1.3	-0.0
Weight	0.2	1.1	1.5	-1.2	-1.2	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	-0.3	0.9	0.1
Pulse rate	0.2	0.3	0.9	0.0	0.3	-0.9
Pulse wave Arterial Stiffness index	0.2	0.2	0.7	0.8	0.1	0.2
Length of working week for main job	0.2	0.2	0.3	0.5	0.1	0.5
Exposure to tobacco smoke outside home	0.2	0.2	0.5	-0.2	0.7	-0.2
Number of full brothers	0.2	0.2	0.4	0.6	0.4	-0.2
Medication: Blood pressure	0.2	0.4	1.1	-0.2	-1.0	-0.0
Medication: Ibuprofen	0.2	0.2	0.3	0.0	-0.6	0.5
Arm predicted mass (right)	0.2	1.0	1.7	-1.1	-1.3	-0.4
Overall health rating	0.2	0.4	0.7	-0.1	0.8	-0.8
Chest pain or discomfort	0.2	0.2	0.3	0.4	0.5	0.5
Hypertension (Self-reported)	0.2	0.5	0.9	0.7	0.2	1.0
Whole body fat-free mass	0.2	1.4	1.8	-1.4	-1.0	-1.1
Leg fat-free mass (right)	0.2	1.0	1.6	-1.0	-0.5	-1.3
Arm fat percentage (left)	0.2	0.6	1.3	-0.8	-1.1	-0.2
Commuting to job workplace: Walk	0.2	0.2	0.3	-0.4	0.5	-0.4
Medication: Gliclazide	0.2	0.2	0.4	0.3	-0.2	0.6
Smoking status: Current	0.2	0.3	0.4	-0.4	-0.6	0.7
Whole body water mass	0.2	1.4	1.9	-1.4	-1.1	-1.1
Leg predicted mass (right)	0.2	0.9	1.5	-0.9	-0.5	-1.2
Risk taking	0.2	0.3	0.6	0.5	0.1	0.8
Diastolic blood pressure, automated reading	0.2	0.7	1.5	-0.1	-0.8	1.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.4	-0.1	-0.6	0.7
Schizophrenia vs Biploar Disorder	0.1	0.1	0.3	0.1	0.5	-0.3
Ulcerative Colitis (UC)	0.1	0.1	0.2	0.5	-0.3	0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.3	0.2	0.6	-0.1
HbA1C	0.1	0.1	0.4	0.1	0.6	0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.3	0.3	0.1	0.6
Blood Red Count	0.1	1.2	2.7	-0.7	-1.6	-0.7
BMI	0.1	0.6	1.4	-0.5	-1.2	0.1
Height	0.1	1.2	3.0	-0.6	1.7	-0.6
Systolic Blood Pressure	0.1	0.6	1.4	0.5	-0.5	1.2
Smoking Status	0.1	0.2	0.3	-0.5	-0.5	0.5
Hair Pigment	0.1	1.7	2.7	1.2	0.9	1.6
Trunk fat percentage	0.1	0.2	0.5	0.4	-0.0	0.7
Current tobacco smoking	0.1	0.2	0.3	-0.6	-0.3	0.3
Body mass index (BMI)	0.1	0.6	1.4	-0.6	-1.2	0.3
Number of incorrect matches in round	0.1	0.1	0.2	-0.1	-0.5	-0.3
Had other major operations	0.1	0.2	0.4	0.0	-0.2	0.6
Forced vital capacity (FVC)	0.1	0.4	1.2	-1.1	-0.1	-0.1
Illnesses of siblings	0.1	0.1	0.2	-0.0	0.4	-0.2
Impedance of arm (right)	0.1	0.4	1.1	0.2	1.0	-0.5
Arm fat percentage (right)	0.1	0.5	1.1	-0.7	-1.0	-0.2
Falls in the last year	0.1	0.2	0.4	0.1	-0.2	-0.6
Hair/balding pattern: Pattern 3	0.1	0.1	0.3	0.1	0.6	0.2
Number of live births	0.1	0.1	0.2	-0.3	0.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.5	-0.3	-0.7	0.1
Impedance of arm (left)	0.1	0.3	0.6	0.1	0.8	-0.4
Arm fat mass (right)	0.1	0.5	0.8	-0.8	-0.9	-0.2
Standing height	0.1	1.3	2.3	-1.2	-0.2	-1.5
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	-0.1	0.6	-0.2
Body fat percentage	0.1	0.5	0.8	-0.1	-0.9	0.8
Arm fat-free mass (right)	0.1	0.7	1.4	-0.9	-1.2	-0.2
Comparative body size at age 10	0.1	0.2	0.6	0.1	0.3	0.8
Pulse wave peak to peak time	0.1	0.2	0.5	-0.7	0.1	-0.1
Whole body fat mass	0.1	0.5	1.3	-0.4	-1.1	0.4
Pulse rate, automated reading	0.1	0.4	1.1	-0.1	-1.1	0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	0.4	0.2	0.0
Smoking status: Previous	0.1	0.2	0.2	-0.5	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.2	0.4	-0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.3	-0.6	-0.4	-0.2
Arm fat mass (left)	0.1	0.5	0.7	-0.8	-0.9	-0.4
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.0	-0.4	-0.2
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.3	-0.4	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.2	0.2	-0.3
Medication: Blood pressure	0.1	0.2	0.5	-0.1	0.2	0.7
Medication: Bendroflumethiazide	0.1	0.1	0.2	-0.4	-0.4	-0.1
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.2	0.1	-0.5
Arm fat-free mass (left)	0.1	0.5	0.9	-0.8	-1.0	-0.2
Myopia	0.1	0.1	0.1	0.4	-0.3	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.4	-0.6	0.0	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	-0.4	-0.1	-0.3
Impedance of whole body	0.1	0.6	0.8	0.7	0.7	0.9
Arm predicted mass (left)	0.1	0.4	0.7	-0.8	-0.8	-0.1
Waist Hip Ratio (WHR)	0.0	0.1	0.2	-0.4	-0.3	0.1
Cardiovascular Disease	0.0	0.1	0.2	-0.4	0.0	-0.3
Tanning	0.0	0.1	0.3	0.3	0.2	-0.5
Trunk fat mass	0.0	0.2	0.4	-0.2	-0.6	0.2
Past tobacco smoking	0.0	0.0	0.1	0.1	0.2	-0.3
Blood clot in the leg (DVT)	0.0	0.0	0.0	0.2	-0.1	0.0
Forced vital capacity (FVC), Best measure	0.0	0.2	0.4	-0.6	0.0	-0.4
Medication: Seretide 50 evohaler	0.0	0.0	0.1	-0.3	-0.1	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	0.0	-0.3	-0.0
Friendships satisfaction	0.0	0.0	0.1	-0.1	-0.4	0.1
Back pain experienced in last month	0.0	0.0	0.1	-0.0	0.0	-0.3
Pain experienced in last month	0.0	0.1	0.2	-0.1	-0.2	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	0.2	-0.1	0.1

Hub : Genes

C22orf45

Models

Trait associations