TWAS hub - C2orf28

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0172	0.0096	9.1e-03	0.009	0.009	0.006	0.01	0.010	3.8e-04	3.6e-04	4.6e-03	0.00019	2.1e-04
2	TCGA	Bladder Urothelial Carcinoma	0.0290	0.0210	9.8e-03	0.026	0.020	0.019	NA	0.020	2.6e-03	7.7e-03	9.0e-03	NA	7.9e-03
3	TCGA	Breast Invasive Carcinoma	0.0813	0.0424	5.2e-11	0.031	0.050	0.054	NA	0.055	4.2e-07	1.5e-10	3.4e-11	NA	2.4e-11
4	TCGA	Cervical Squamous Cell Carcinoma	0.2350	0.1880	1.2e-03	0.003	-0.005	-0.003	NA	0.003	2.2e-01	7.7e-01	4.6e-01	NA	2.1e-01
5	TCGA	Colon Adenocarcinoma	0.0700	0.0360	3.4e-05	0.092	0.069	0.071	NA	0.083	5.5e-06	8.4e-05	6.5e-05	NA	1.6e-05
6	TCGA	Esophageal Carcinoma	0.3040	0.1290	8.3e-05	0.039	0.103	0.106	NA	0.088	2.2e-02	3.6e-04	3.0e-04	NA	9.7e-04
7	TCGA	Glioblastoma Multiforme	0.1380	0.1120	4.1e-03	0.017	0.034	0.014	NA	0.050	9.5e-02	3.3e-02	1.2e-01	NA	1.2e-02
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0227	0.0165	6.5e-03	0.014	0.014	0.006	NA	0.010	8.6e-03	8.5e-03	5.5e-02	NA	2.6e-02
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0369	0.0288	8.2e-03	0.015	0.004	0.005	NA	0.005	7.5e-03	9.3e-02	7.3e-02	NA	7.9e-02
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0540	0.0390	9.7e-03	0.002	-0.003	-0.004	NA	0.014	2.4e-01	4.8e-01	7.4e-01	NA	4.8e-02
11	TCGA	Brain Lower Grade Glioma	0.0329	0.0207	2.2e-03	0.025	0.012	0.009	NA	0.015	6.1e-04	1.6e-02	2.9e-02	NA	6.9e-03
12	TCGA	Liver Hepatocellular Carcinoma	0.0670	0.0440	4.5e-03	0.040	0.043	0.024	NA	0.026	5.8e-03	4.1e-03	2.5e-02	NA	2.2e-02
13	TCGA	Lung Adenocarcinoma	0.0276	0.0224	6.1e-03	0.018	0.017	0.025	NA	0.013	3.2e-03	3.7e-03	5.8e-04	NA	9.5e-03
14	TCGA	Lung Squamous Cell Carcinoma	0.0194	0.0132	7.7e-03	0.007	0.016	0.010	NA	0.010	4.4e-02	6.0e-03	2.5e-02	NA	2.1e-02
15	TCGA	Pheochromocytoma and Paraganglioma	0.0740	0.0560	8.5e-03	0.033	0.052	0.044	NA	0.057	1.8e-02	4.2e-03	7.3e-03	NA	2.8e-03
16	TCGA	Prostate Adenocarcinoma	0.1609	0.0757	5.0e-14	0.111	0.134	0.137	NA	0.149	1.1e-11	6.7e-14	3.4e-14	NA	2.5e-15
17	TCGA	Stomach Adenocarcinoma	0.0590	0.0330	6.4e-05	0.050	0.046	0.050	NA	0.054	1.5e-04	2.7e-04	1.5e-04	NA	8.9e-05
18	TCGA	Testicular Germ Cell Tumors	0.1030	0.0700	9.4e-03	-0.001	0.024	0.001	NA	0.003	3.4e-01	4.8e-02	2.9e-01	NA	2.5e-01
19	TCGA	Thyroid Carcinoma	0.0980	0.0590	4.7e-07	0.076	0.063	0.071	NA	0.069	7.4e-08	9.1e-07	1.9e-07	NA	3.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Triglycerides	37.5	61.5	94.7	-6.0	-9.5	-9.2	-9.7	-5.8	-9.1	-7.2	-6.7	-5.1	-8.7	-4.2	-9.3	-7.6	-9.1	-5.8	-6.5	-7.8	-9.1	-9.2
Fasting Glucose	11.8	14.1	22.2	3.9	4.0	3.9	2.5	4.3	3.0	3.7	3.8	1.5	4.7	3.3	4.3	3.2	3.8	3.7	4.0	4.4	3.5	4.2
High cholesterol (Self-reported)	9.9	17.6	26.5	-2.0	-5.0	-4.8	-5.1	-4.4	-5.2	-3.7	-3.6	-3.0	-4.6	-2.2	-4.8	-4.1	-4.8	-3.0	-3.3	-4.1	-4.9	-4.9
Blood Platelet Count	8.5	98.4	144.0	-9.8	-10.9	-9.9	-8.4	-11.4	-9.6	-10.4	-9.8	-5.5	-12.0	-8.2	-11.3	-8.6	-10.0	-9.4	-9.5	-11.4	-9.8	-10.6
Alcohol intake frequency.	8.0	18.7	29.6	-2.9	-5.1	-4.8	-3.9	-5.2	-5.0	-4.7	-3.5	-1.4	-5.4	-2.6	-5.4	-3.0	-5.4	-3.5	-3.9	-4.8	-4.1	-4.9
Gout (self-reported)	7.5	10.3	13.8	-3.0	-3.4	-3.1	-2.5	-3.7	-3.0	-3.5	-3.4	-2.0	-3.7	-3.0	-3.6	-2.9	-3.0	-3.3	-3.2	-3.7	-3.1	-3.4
Medication for pain relief, constipation, heartburn	7.5	12.8	26.1	2.9	2.8	2.2	1.7	3.7	1.8	4.3	4.8	2.6	3.9	5.1	3.0	3.8	1.1	5.1	4.8	4.5	3.1	3.1
Had menopause	6.7	8.3	14.4	3.6	2.8	2.3	1.0	3.6	1.9	3.8	3.2	0.6	3.2	3.4	3.1	2.2	2.3	3.5	3.1	3.5	2.2	3.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	6.3	7.4	10.3	-1.9	-3.1	-2.9	-2.7	-3.1	-3.1	-2.8	-2.6	-1.6	-3.1	-1.9	-3.2	-2.3	-2.9	-2.5	-2.7	-2.9	-2.9	-2.9
Blood White Count	6.1	45.0	60.7	-7.1	-7.6	-7.3	-6.8	-7.4	-7.1	-6.2	-6.4	-4.8	-7.8	-4.7	-7.7	-5.8	-7.1	-5.6	-5.9	-7.2	-7.1	-6.9
Stomach or abdominal pain in last month	5.9	7.3	12.9	-3.6	-2.9	-2.9	-2.3	-3.1	-2.7	-2.4	-2.4	-1.8	-3.2	-1.9	-3.1	-2.0	-2.9	-2.5	-2.9	-2.9	-2.7	-2.5
Medication: Paracetamol	5.5	9.0	17.7	-2.0	-2.8	-2.6	-1.8	-3.3	-2.2	-3.0	-3.4	-2.5	-3.5	-3.4	-3.0	-3.0	-2.0	-3.8	-4.2	-3.6	-2.8	-2.8
Migraine (self-reported)	5.3	6.6	16.6	-1.6	-2.5	-1.8	-2.7	-2.1	-2.4	-2.6	-3.0	-2.1	-2.2	-2.6	-2.1	-4.1	-1.2	-2.8	-2.5	-2.5	-3.0	-3.4
Illnesses of siblings: Diabetes	5.2	6.4	10.0	1.8	2.9	3.0	2.8	2.5	3.1	1.4	2.2	2.9	2.3	1.3	2.8	2.7	2.8	2.1	2.6	2.2	3.2	2.5
Vitamin and mineral supplements	5.1	6.9	12.1	1.9	2.3	2.2	1.6	3.0	1.3	2.7	3.3	2.4	3.3	3.3	2.5	2.7	1.5	3.3	3.1	3.5	2.4	2.3
Number of operations (self-reported)	5.1	7.6	14.7	-1.2	-2.3	-1.7	-1.3	-2.8	-1.6	-3.4	-3.4	-1.8	-2.8	-3.7	-2.3	-3.6	-1.1	-3.8	-3.6	-3.3	-2.5	-3.1
High blood pressure (mother)	4.8	6.8	11.8	-2.0	-2.5	-2.2	-2.4	-2.6	-2.0	-2.9	-3.4	-2.4	-2.4	-3.0	-2.4	-3.1	-1.3	-2.9	-2.4	-2.9	-2.9	-2.7
Eye problems/disorders: None of the above	4.8	5.6	7.5	2.1	2.5	2.4	1.5	2.7	2.1	2.3	2.4	1.8	2.4	2.2	2.5	2.6	2.2	2.6	2.7	2.5	2.4	2.7
Multivitamins +/- minerals	4.7	5.9	9.0	-2.3	-2.3	-2.2	-2.4	-2.4	-1.8	-2.2	-3.0	-2.6	-2.9	-2.6	-2.2	-2.6	-1.4	-2.7	-2.5	-3.0	-2.6	-2.1
Illnesses of mother	4.7	5.9	8.6	2.4	2.5	2.3	2.4	2.5	2.0	2.5	2.9	2.4	2.4	2.5	2.4	2.7	1.6	2.5	2.3	2.6	2.7	2.4
Neuroticism	4.5	10.9	15.7	-3.2	-3.3	-2.9	-3.0	-3.3	-2.9	-3.5	-3.9	-2.9	-3.0	-3.4	-3.1	-4.0	-2.0	-3.7	-3.5	-3.4	-3.7	-3.5
Medication: Simvastatin	4.5	6.6	8.9	-0.8	-2.9	-2.7	-3.0	-2.6	-2.9	-2.3	-2.4	-1.9	-3.0	-1.7	-2.8	-2.8	-2.5	-2.3	-2.5	-2.7	-3.0	-2.9
Had other major operations	4.4	5.4	10.2	-0.5	-2.0	-1.8	-0.6	-2.8	-1.2	-2.7	-2.7	-1.3	-2.9	-3.0	-2.3	-2.5	-1.6	-3.1	-3.2	-3.0	-1.8	-2.4
Number of treatments/medications taken	4.2	7.5	13.5	-1.7	-2.6	-2.2	-1.8	-3.2	-1.9	-3.3	-3.1	-1.4	-3.7	-3.2	-2.8	-2.4	-1.9	-3.3	-3.3	-3.7	-2.4	-2.6
Medication for cholesterol	4.1	6.3	10.1	0.4	2.5	2.2	2.2	2.8	2.0	3.0	3.0	1.6	3.2	2.8	2.6	2.2	1.7	2.9	2.9	3.2	2.4	2.3
Medication: Paracetamol	4.1	6.4	12.2	-1.7	-2.4	-2.1	-1.6	-2.8	-2.0	-2.4	-2.7	-1.9	-3.2	-2.6	-2.6	-2.5	-1.9	-3.1	-3.5	-3.2	-2.3	-2.5
Medication: Atorvastatin	4.0	5.0	6.8	-1.9	-2.6	-2.5	-2.3	-2.5	-2.6	-2.0	-2.0	-1.6	-2.5	-1.3	-2.6	-2.0	-2.5	-1.8	-2.1	-2.3	-2.4	-2.4
Schizophrenia vs Biploar Disorder	3.9	5.1	8.5	2.5	2.6	2.1	1.5	2.5	2.5	2.9	1.9	0.1	2.5	1.8	2.8	1.8	2.7	2.1	2.1	2.4	1.9	2.9
Medication: Ibuprofen (e.g. Nurofen)	3.9	5.0	12.9	-1.6	-1.6	-1.1	-0.1	-2.5	-0.6	-3.1	-3.0	-0.9	-2.3	-3.6	-1.8	-2.3	-0.7	-3.3	-2.9	-2.9	-1.5	-2.2
Bilateral oophorectomy (both ovaries removed)	3.8	4.4	6.9	-2.3	-2.0	-1.8	-1.1	-2.4	-1.4	-2.5	-2.4	-1.1	-2.4	-2.4	-2.2	-1.9	-1.5	-2.5	-2.6	-2.5	-1.8	-2.1
Supplements: Fish oil (including cod liver oil)	3.8	5.0	7.6	-2.8	-2.1	-2.0	-2.0	-2.2	-1.6	-1.8	-2.6	-2.5	-2.5	-2.2	-2.1	-2.5	-1.4	-2.4	-2.5	-2.6	-2.4	-1.9
Medication: Ibuprofen	3.7	4.4	9.5	-1.9	-1.7	-1.2	-0.4	-2.4	-0.8	-2.9	-2.7	-0.8	-2.4	-3.1	-1.9	-2.0	-1.0	-2.9	-2.5	-2.8	-1.4	-2.1
Medication: Allopurinol	3.6	4.8	6.6	-1.6	-2.4	-2.0	-2.0	-2.4	-2.2	-2.6	-2.4	-1.3	-2.5	-2.0	-2.4	-2.0	-1.9	-2.3	-2.2	-2.5	-2.2	-2.3
Eye problems/disorders: Cataract	3.6	4.2	6.8	-2.4	-1.9	-1.6	-1.0	-2.4	-1.3	-2.6	-2.3	-0.8	-2.2	-2.5	-2.1	-1.8	-1.5	-2.6	-2.4	-2.5	-1.7	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	3.5	3.8	5.8	-0.1	-2.1	-2.1	-1.2	-2.4	-1.4	-1.6	-1.9	-1.6	-2.3	-1.7	-2.2	-2.1	-2.1	-2.0	-2.1	-2.3	-1.9	-2.2
Cholesterol lowering medication	3.5	5.1	8.7	-0.4	-2.7	-2.7	-3.0	-2.3	-2.8	-1.7	-2.1	-2.3	-2.5	-1.1	-2.6	-2.1	-2.5	-1.6	-1.9	-2.2	-2.7	-2.2
Ever highly irritable/argumentative for 2 days	3.4	4.1	6.8	-1.6	-2.2	-2.2	-1.6	-2.6	-1.4	-2.1	-2.2	-1.4	-2.6	-1.9	-2.4	-1.4	-2.1	-2.0	-1.9	-2.5	-2.0	-1.8
Hair/balding pattern: Pattern 2	3.3	4.2	5.7	-2.3	-2.4	-2.2	-2.0	-2.2	-2.4	-2.1	-1.9	-1.2	-2.0	-1.4	-2.3	-1.9	-2.2	-1.7	-1.8	-1.9	-2.2	-2.4
Supplements: Calcium	3.3	3.6	6.3	-0.7	-1.9	-2.0	-1.1	-2.3	-1.4	-1.3	-1.9	-1.9	-2.4	-1.7	-2.1	-1.9	-1.9	-2.1	-2.5	-2.3	-1.8	-1.8
Depression (Nagel 2018)	3.2	4.9	7.5	-2.7	-2.2	-2.0	-2.4	-2.3	-1.9	-2.2	-2.6	-2.0	-2.5	-2.0	-2.2	-2.0	-1.5	-2.2	-2.0	-2.5	-2.4	-1.9
Mouth/teeth dental problems	3.2	4.9	7.5	0.6	2.6	2.4	2.5	2.4	2.6	2.0	1.8	1.5	2.5	1.2	2.6	2.3	2.6	1.7	1.9	2.2	2.5	2.7
Mouth/teeth dental problems: Bleeding gums	3.1	4.0	8.1	-1.2	-2.4	-2.1	-2.3	-1.9	-2.9	-1.8	-1.5	-1.0	-1.8	-0.9	-2.2	-2.4	-2.3	-1.5	-1.7	-1.6	-2.4	-2.9
Medication: Cholesterol lowering	3.0	4.6	7.0	-1.1	-2.5	-2.2	-2.4	-2.3	-2.4	-2.0	-1.9	-1.3	-2.6	-1.4	-2.4	-2.2	-2.3	-1.7	-1.8	-2.4	-2.4	-2.6
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.4	6.9	-1.6	-2.1	-1.8	-1.1	-2.2	-1.7	-2.0	-1.5	-0.5	-2.1	-1.4	-2.1	-2.0	-2.2	-1.6	-1.8	-1.9	-1.7	-2.6
High blood pressure (siblings)	2.6	3.7	6.8	-0.9	-1.8	-1.5	-1.1	-2.3	-1.3	-2.6	-2.6	-1.2	-2.1	-2.6	-1.9	-1.7	-1.1	-2.5	-2.1	-2.4	-1.7	-1.7
Health satisfaction	2.6	3.4	5.8	-2.2	-1.8	-1.4	-1.7	-1.8	-1.5	-2.2	-2.1	-1.1	-1.8	-1.9	-1.7	-2.4	-1.1	-1.8	-1.4	-2.0	-2.0	-2.4
Had major operations	2.6	3.0	5.7	-1.8	-1.7	-1.3	-2.0	-1.4	-1.8	-1.8	-2.0	-1.6	-1.3	-1.6	-1.4	-2.4	-0.7	-1.9	-1.8	-1.6	-2.1	-1.9
Miserableness	2.6	4.4	6.2	-1.1	-2.4	-2.4	-2.0	-2.4	-2.3	-1.9	-2.1	-1.8	-2.3	-1.6	-2.5	-1.6	-2.2	-2.0	-2.3	-2.2	-2.3	-1.9
Average weekly spirits intake	2.5	3.1	5.0	-0.6	-2.0	-1.9	-2.0	-1.8	-2.2	-1.5	-1.6	-1.4	-1.9	-1.1	-2.0	-1.9	-1.8	-1.5	-1.8	-1.7	-2.1	-2.0
Neuroticism (2016)	2.4	3.5	5.5	-1.9	-2.1	-2.1	-1.5	-2.4	-1.8	-1.7	-1.9	-1.4	-1.9	-1.7	-2.2	-1.4	-2.0	-1.8	-1.9	-1.9	-2.0	-1.7
Leg predicted mass (left)	2.4	12.6	24.6	5.0	3.8	3.2	4.7	3.0	4.1	3.1	3.3	2.6	3.8	2.2	3.4	4.1	2.9	2.6	2.5	3.5	4.1	4.1
Whole body fat-free mass	2.4	13.8	24.3	4.8	4.0	3.3	4.9	3.3	4.3	3.7	3.6	2.2	4.1	2.5	3.7	4.1	3.0	2.7	2.4	3.8	4.2	4.4
Leg predicted mass (right)	2.4	12.7	23.0	4.8	3.9	3.3	4.6	3.2	4.2	3.1	3.3	2.6	3.9	2.2	3.5	3.9	3.1	2.6	2.6	3.5	4.1	4.1
Schizophrenia (2018)	2.3	4.7	12.6	3.0	1.4	0.8	0.6	2.2	0.6	3.1	3.0	0.9	2.0	3.6	1.5	2.2	0.1	3.1	2.5	2.7	1.5	1.9
Reaction Time	2.3	4.3	7.4	0.6	2.6	2.5	2.4	2.1	2.5	1.5	1.6	1.7	2.2	0.9	2.4	2.4	2.6	1.3	1.6	1.9	2.4	2.7
Medication: Co-codamol	2.3	2.7	6.5	0.1	-2.0	-2.3	-1.1	-2.1	-2.0	-0.9	-1.1	-1.4	-1.9	-0.6	-2.2	-1.2	-2.6	-1.1	-1.7	-1.5	-1.7	-1.7
Leg fat-free mass (left)	2.3	12.4	24.0	4.9	3.7	3.2	4.6	3.0	4.1	3.1	3.3	2.5	3.8	2.2	3.4	4.1	2.9	2.6	2.5	3.5	4.1	4.1
Townsend deprivation index at recruitment	2.3	3.2	7.0	1.7	1.4	0.9	1.0	1.7	0.8	2.4	2.4	1.0	1.6	2.6	1.3	2.5	0.3	2.4	1.8	2.1	1.7	2.1
Pulse rate, automated reading	2.3	7.3	19.7	-1.2	-3.6	-3.8	-3.4	-3.0	-3.7	-1.5	-1.4	-1.8	-3.1	-0.0	-3.6	-1.4	-4.4	-0.8	-1.6	-2.3	-3.0	-2.7
Medication: Bendroflumethiazide	2.3	3.5	8.0	-0.2	-2.2	-2.2	-2.8	-1.9	-2.2	-1.6	-2.0	-2.0	-2.0	-1.1	-2.1	-1.5	-1.7	-1.4	-1.5	-1.8	-2.4	-1.5
Depressed Affect (Nagel 2018)	2.2	4.7	6.4	-1.8	-2.3	-2.0	-2.3	-2.2	-2.2	-2.2	-2.5	-1.9	-2.1	-1.9	-2.2	-2.5	-1.6	-2.1	-2.1	-2.2	-2.5	-2.3
Diabetes (mother)	2.2	2.9	8.0	-0.1	2.3	2.2	1.6	2.0	2.4	1.4	0.9	0.6	1.8	0.3	2.3	1.0	2.8	0.8	1.2	1.4	1.7	2.0
Mean time to correctly identify matches	2.2	4.1	7.8	0.3	2.5	2.8	2.6	2.0	2.8	0.7	1.3	2.4	1.9	0.3	2.4	2.1	2.8	1.0	1.6	1.5	2.6	2.1
Illness, injury, bereavement, stress in last 2 years	2.2	2.6	5.0	0.6	2.0	1.7	2.1	1.5	2.2	1.4	1.0	0.5	2.0	0.5	1.9	1.7	2.1	1.0	1.2	1.6	1.8	2.2
Leg fat-free mass (right)	2.2	11.9	22.3	4.7	3.8	3.2	4.5	3.0	4.1	3.0	3.1	2.4	3.8	2.0	3.4	3.8	3.0	2.5	2.4	3.4	4.0	4.0
Whole body water mass	2.2	12.4	22.5	4.7	3.8	3.1	4.7	3.1	4.1	3.5	3.4	2.0	3.9	2.3	3.5	3.9	2.8	2.6	2.2	3.6	4.0	4.1
Trunk fat-free mass	2.1	12.0	21.1	4.5	3.7	2.9	4.6	3.1	4.0	3.9	3.4	1.6	3.8	2.5	3.4	3.8	2.7	2.6	2.0	3.6	3.9	4.2
Trunk predicted mass	2.1	12.1	21.6	4.4	3.8	2.9	4.7	3.1	4.0	3.9	3.4	1.6	3.9	2.5	3.4	3.7	2.7	2.6	2.0	3.6	3.9	4.2
Arm fat-free mass (right)	2.1	10.6	22.6	4.4	3.5	2.9	4.8	2.8	3.9	3.2	3.2	2.0	3.5	2.1	3.1	3.4	2.5	2.3	1.8	3.3	3.8	3.6
Loneliness, isolation	2.1	2.9	4.0	-1.7	-2.0	-2.0	-1.9	-1.8	-2.0	-1.2	-1.5	-1.6	-1.7	-0.9	-1.9	-1.6	-1.9	-1.3	-1.5	-1.6	-2.0	-1.8
Mineral and other dietary supplements	2.1	2.9	4.2	1.6	1.9	1.9	1.9	1.7	1.8	1.0	1.4	1.8	2.0	0.9	1.8	1.8	1.8	1.3	1.6	1.8	1.9	1.8
Hand grip strength (left)	2.0	5.1	12.7	1.4	2.3	1.6	1.3	2.8	1.8	3.6	2.4	-0.3	2.7	2.6	2.5	1.8	1.9	2.5	2.1	2.8	1.8	2.9
Maternal smoking around birth	2.0	2.9	5.9	1.5	1.4	1.3	1.8	1.4	1.2	1.3	2.2	2.2	1.5	1.9	1.2	2.4	0.4	2.1	1.9	1.8	2.0	1.5
Time employed in main current job	2.0	2.3	6.5	-0.7	1.9	2.3	1.6	1.9	1.8	0.6	0.8	1.4	2.0	0.2	2.1	0.5	2.5	0.6	1.2	1.5	1.5	1.1
Average weekly champagne plus white wine intake	2.0	2.8	5.3	2.3	1.8	1.7	2.0	1.5	1.9	1.5	1.5	1.4	1.6	1.0	1.6	2.0	1.4	1.2	1.3	1.5	1.9	2.0
Basal metabolic rate	2.0	11.2	22.5	4.7	3.5	2.9	4.5	2.9	3.9	3.1	3.2	2.2	3.6	2.2	3.2	3.8	2.6	2.5	2.2	3.4	3.9	3.9
Bipolar Disorder (2018)	1.9	3.0	9.3	0.2	-2.3	-2.6	-1.9	-1.8	-2.5	-0.7	-0.8	-1.3	-2.0	0.1	-2.4	-0.8	-3.0	-0.5	-1.3	-1.4	-1.8	-1.6
Neuroticism score	1.9	4.1	6.2	-1.5	-2.3	-2.2	-2.5	-2.0	-2.4	-1.8	-2.1	-2.0	-1.8	-1.4	-2.1	-2.1	-1.8	-1.8	-1.9	-1.8	-2.5	-2.0
Commuting to job workplace: Car/motor vehicle	1.9	2.1	7.5	-1.2	-1.2	-0.2	-0.6	-1.3	-0.9	-2.7	-1.5	1.1	-1.4	-1.9	-1.1	-1.9	-0.5	-1.6	-0.9	-1.7	-0.9	-2.5
Mood swings	1.9	3.4	5.5	-0.6	-1.8	-1.6	-1.4	-2.0	-1.5	-1.9	-2.3	-1.9	-1.6	-2.1	-1.8	-2.2	-1.1	-2.2	-2.2	-1.9	-2.0	-1.8
Type 2 Diabetes (T2D) (2018)	1.8	3.3	7.1	1.7	1.9	1.6	2.7	1.5	2.0	1.6	1.9	1.5	2.0	1.2	1.6	2.3	1.2	1.4	1.1	1.9	2.2	2.1
Sitting height	1.8	12.4	22.4	4.3	3.8	2.9	3.4	3.7	3.5	4.7	3.5	0.5	4.2	3.1	3.7	3.3	3.1	3.0	2.3	4.0	3.3	4.5
Arm predicted mass (right)	1.8	9.4	20.7	4.2	3.3	2.7	4.5	2.6	3.8	3.1	2.9	1.7	3.3	1.8	3.0	3.2	2.4	2.0	1.6	3.0	3.6	3.5
Number of full sisters	1.8	2.2	4.4	2.1	1.5	1.5	1.5	1.5	1.2	1.2	1.7	1.7	1.4	1.3	1.5	1.4	1.1	1.4	1.5	1.5	1.7	1.2
Alcohol intake versus 10 years previously	1.7	2.5	6.3	-2.5	-1.1	-0.7	-0.6	-1.5	-0.9	-1.8	-1.7	-0.6	-1.6	-2.1	-1.2	-1.8	-0.5	-2.2	-2.2	-1.9	-1.2	-1.6
Lung cancer (father)	1.7	2.0	5.8	1.3	0.6	0.3	0.6	1.0	0.2	1.6	2.2	1.5	1.1	2.4	0.6	2.1	-0.6	2.2	1.8	1.6	1.2	1.1
Financial situation satisfaction	1.7	2.1	4.5	-2.1	-1.1	-1.0	-0.7	-1.7	-0.3	-1.8	-2.0	-1.0	-1.6	-2.1	-1.2	-1.0	-0.5	-1.9	-1.5	-1.9	-1.1	-0.9
Systolic Blood Pressure	1.6	8.1	16.5	-2.6	-2.5	-1.8	-2.6	-2.8	-2.2	-4.1	-3.8	-1.5	-2.9	-3.7	-2.5	-3.0	-0.9	-3.6	-2.9	-3.4	-2.9	-2.8
Alcohol usually taken with meals	1.6	2.6	4.8	-1.9	-1.2	-1.1	-1.4	-1.4	-0.5	-1.3	-2.2	-2.1	-1.7	-2.1	-1.1	-2.0	-0.3	-2.1	-1.8	-2.0	-1.6	-1.1
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	4.1	1.1	1.5	1.3	1.8	1.6	1.3	1.7	2.0	1.3	1.9	1.8	1.4	1.9	0.8	1.8	1.6	2.0	1.8	1.6
Alcohol drinker status: Never	1.6	1.9	7.6	0.0	-1.8	-1.9	-1.5	-1.6	-2.1	-0.8	-0.1	0.2	-1.9	0.5	-2.0	0.1	-2.8	0.0	-0.5	-1.1	-1.1	-1.3
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.3	1.1	1.6	1.7	1.2	1.8	1.5	1.6	1.2	0.5	1.0	0.8	1.5	1.3	1.5	0.8	0.8	0.9	1.4	1.8
Impedance of leg (left)	1.5	7.2	15.6	-3.3	-3.0	-2.9	-4.0	-1.9	-3.9	-0.9	-1.8	-3.1	-2.5	-0.5	-2.6	-3.1	-2.8	-1.3	-2.1	-2.0	-3.4	-2.7
Happiness	1.5	1.8	5.1	-1.5	-1.3	-0.8	-1.0	-1.5	-0.8	-2.2	-1.4	0.6	-1.6	-1.6	-1.3	-1.3	-0.9	-1.3	-0.8	-1.6	-1.0	-2.0
Qualifications: A levels/AS levels or equivalent	1.5	3.4	7.1	0.7	2.2	2.4	1.3	2.5	1.7	1.5	1.5	1.3	2.5	1.1	2.5	0.7	2.7	1.4	1.7	2.2	1.7	1.5
Exposure to tobacco smoke outside home	1.5	2.0	4.1	-0.6	-1.7	-1.9	-1.4	-1.8	-1.5	-1.1	-1.1	-1.2	-1.8	-0.5	-1.9	-0.5	-2.0	-0.9	-1.2	-1.4	-1.4	-1.0
Comparative height size at age 10	1.5	8.2	15.9	2.3	3.3	2.5	3.0	3.1	3.1	3.8	2.6	0.2	3.4	2.1	3.2	2.8	2.9	2.1	1.6	3.2	2.8	4.0
Overall health rating	1.5	3.2	8.6	0.2	-2.3	-2.3	-1.4	-2.2	-2.4	-1.6	-0.9	-0.5	-1.9	-0.5	-2.4	-1.2	-2.9	-1.1	-1.6	-1.5	-1.8	-2.3
Illnesses of father: Heart disease	1.5	2.1	3.5	-1.2	-1.7	-1.4	-0.7	-1.8	-1.5	-1.7	-1.2	-0.3	-1.8	-1.1	-1.8	-1.2	-1.8	-1.4	-1.6	-1.6	-1.2	-1.9
Friendships satisfaction	1.5	1.9	3.6	-1.2	-1.8	-1.7	-1.6	-1.5	-1.7	-1.2	-1.0	-0.7	-1.4	-0.4	-1.7	-1.2	-1.9	-0.7	-0.7	-1.2	-1.5	-1.7
Arm fat-free mass (left)	1.5	7.8	17.8	4.2	2.9	2.4	4.0	2.3	3.2	2.7	2.8	1.8	3.1	1.9	2.6	3.0	2.0	2.0	1.6	2.8	3.2	3.1
Average weekly beer plus cider intake	1.5	2.2	5.3	1.5	0.9	0.7	0.2	1.6	0.3	1.7	1.9	0.9	1.8	2.3	1.2	1.2	0.4	2.3	2.3	2.0	0.9	1.0
Basal cell carcinoma (self-reported)	1.5	1.7	4.6	-0.3	-1.1	-1.0	-1.4	-0.9	-1.1	-0.6	-1.5	-2.1	-1.1	-1.3	-0.9	-2.1	-0.4	-1.6	-1.9	-1.2	-1.6	-1.2
Arm predicted mass (left)	1.5	7.6	17.1	4.1	2.9	2.3	4.0	2.3	3.2	2.7	2.7	1.7	3.1	1.8	2.6	2.9	2.0	1.9	1.5	2.8	3.1	3.0
Ulcerative Colitis (UC)	1.4	2.7	5.5	-0.6	-1.5	-1.5	-1.7	-1.5	-1.2	-1.4	-2.2	-2.4	-1.5	-1.8	-1.4	-1.9	-0.8	-1.9	-1.7	-1.8	-1.9	-1.3
Prostate Cancer	1.4	1.9	5.5	0.6	-1.7	-1.7	-2.2	-0.9	-2.4	-0.2	-0.6	-1.6	-0.8	0.3	-1.4	-1.8	-1.8	-0.3	-1.0	-0.5	-1.9	-1.7
Medication: Metformin	1.4	2.0	4.2	1.1	1.5	1.5	2.1	1.3	1.3	1.1	1.7	1.9	1.5	1.1	1.4	1.4	1.0	1.1	1.0	1.5	1.8	1.1
Average weekly red wine intake	1.4	2.0	7.4	0.7	1.9	1.9	1.6	1.5	2.2	1.1	0.2	-0.4	1.6	-0.5	2.1	-0.3	2.7	-0.0	0.3	1.0	1.2	1.3
Medication for hormone replacement therapy	1.3	1.5	2.6	-0.1	-1.4	-1.2	-0.8	-1.4	-1.2	-1.4	-0.9	0.0	-1.6	-0.9	-1.5	-1.0	-1.5	-1.2	-1.4	-1.4	-1.0	-1.6
Impedance of leg (right)	1.3	6.4	14.2	-3.0	-2.9	-2.9	-3.8	-1.9	-3.7	-0.9	-1.6	-2.8	-2.5	-0.3	-2.6	-2.6	-2.8	-1.1	-1.9	-1.9	-3.2	-2.5
Weight	1.3	6.5	21.1	4.6	2.5	2.1	3.2	2.0	2.6	1.9	2.5	2.4	2.6	1.7	2.2	3.1	1.7	2.0	1.9	2.5	2.9	2.6
Standing height	1.3	12.8	30.4	3.5	3.9	2.7	3.6	3.9	3.4	5.5	3.7	-0.4	4.2	3.3	3.8	3.3	3.0	3.0	1.6	4.2	3.2	4.9
Chest pain or discomfort	1.3	1.9	4.3	0.0	-1.6	-2.1	-1.8	-1.5	-1.8	-0.4	-0.8	-1.8	-1.7	-0.0	-1.7	-0.4	-2.0	-0.6	-1.1	-1.2	-1.5	-0.7
Schizophrenia (2014)	1.2	2.6	8.4	2.6	0.6	0.1	0.4	1.2	0.2	2.4	2.3	0.7	1.2	2.9	0.7	1.8	-0.7	2.5	1.9	1.8	1.1	1.1
Height	1.2	23.8	43.0	4.2	5.6	4.5	5.9	5.2	5.3	6.6	5.0	1.2	5.4	3.9	5.3	4.3	4.5	3.8	2.5	5.3	5.1	6.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.5	-0.7	-0.8	-0.7	-0.5	-0.9	-0.5	-0.8	-1.6	-1.9	-0.7	-1.6	-0.7	-1.9	-0.1	-1.6	-1.7	-1.1	-1.2	-1.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.8	-0.0	-1.5	-1.3	-1.7	-1.2	-1.5	-1.2	-0.9	-0.4	-1.5	-0.5	-1.4	-1.2	-1.5	-0.6	-0.6	-1.3	-1.3	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	3.6	-0.8	-1.4	-1.0	-1.1	-1.5	-1.3	-1.9	-1.4	-0.1	-1.6	-1.3	-1.4	-1.3	-1.1	-1.4	-1.3	-1.6	-1.2	-1.7
Medication: Seretide 50 evohaler	1.2	1.4	4.5	1.9	1.1	1.3	1.8	0.8	1.3	0.2	1.2	2.1	0.8	0.5	1.0	1.0	0.7	0.8	1.0	0.8	1.6	0.5
Supplements: Vitamin C	1.2	1.5	4.7	-0.9	-0.5	-0.4	0.6	-1.3	0.4	-1.1	-1.6	-1.1	-1.1	-2.2	-0.7	-1.4	0.1	-2.0	-1.9	-1.6	-0.6	-0.8
Mother’s age at death	1.2	1.5	3.1	-0.0	1.5	1.6	0.7	1.7	1.2	1.0	1.1	0.8	1.5	0.8	1.7	0.4	1.8	1.0	1.4	1.3	1.1	0.9
Impedance of whole body	1.2	6.0	18.1	-2.9	-2.7	-2.6	-4.2	-1.6	-3.7	-1.0	-1.7	-2.6	-2.3	-0.3	-2.3	-2.7	-2.3	-1.0	-1.4	-1.8	-3.3	-2.5
Age at First Birth	1.1	1.6	3.1	-1.6	-1.1	-1.1	-1.3	-0.5	-0.8	-0.8	-1.5	-1.8	-1.3	-1.3	-1.1	-1.6	-0.5	-1.5	-1.7	-1.4	-1.4	-1.1
Chronotype (morning person)	1.1	2.5	5.9	-1.1	-1.9	-2.4	-2.0	-1.6	-2.1	-0.1	-0.8	-2.2	-1.5	0.2	-2.0	-0.7	-2.4	-0.7	-1.5	-1.1	-1.9	-0.8
Serious illness, injury or assault to yourself	1.1	1.3	2.9	-0.4	-1.2	-0.9	-0.6	-1.3	-1.2	-1.5	-0.9	0.2	-1.4	-1.0	-1.3	-1.2	-1.3	-1.1	-1.2	-1.3	-0.9	-1.7
Ulcerative Colitis	1.0	1.5	2.7	0.8	-1.2	-1.0	-1.3	-1.0	-1.0	-1.3	-1.6	-1.2	-1.1	-1.4	-1.1	-1.6	-0.6	-1.3	-1.0	-1.3	-1.4	-1.4
Systolic blood pressure, automated reading	1.0	3.0	10.2	-2.2	-1.2	-0.4	-1.3	-1.5	-0.7	-3.2	-2.4	0.2	-1.8	-2.6	-1.2	-1.5	0.1	-2.2	-1.2	-2.2	-1.2	-1.7
Diabetes (self-reported)	1.0	1.5	5.2	0.1	1.6	1.6	2.3	0.9	1.9	0.7	0.4	0.6	1.2	-0.4	1.4	0.8	1.8	-0.1	-0.1	0.7	1.4	1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	3.6	-0.8	1.4	1.7	1.7	0.9	1.6	-0.2	0.5	1.9	0.9	-0.3	1.3	0.9	1.6	0.3	0.8	0.6	1.5	0.8
Falls in the last year	1.0	1.4	3.1	-0.3	-1.3	-1.2	-0.5	-1.6	-1.0	-1.3	-1.0	-0.1	-1.8	-1.0	-1.5	-0.6	-1.6	-1.1	-1.2	-1.6	-0.8	-1.4
Mouth/teeth dental problems: Dentures	1.0	1.7	2.5	-0.4	-1.4	-1.2	-1.3	-1.3	-1.2	-1.2	-1.5	-1.4	-1.4	-1.1	-1.3	-1.6	-1.0	-1.3	-1.4	-1.4	-1.5	-1.4
Heart disease (mother)	1.0	1.2	2.3	-0.7	-1.1	-1.2	-1.2	-1.0	-1.1	-0.8	-1.1	-1.5	-1.0	-0.7	-1.0	-1.5	-0.9	-1.0	-1.2	-1.0	-1.3	-1.2
Medication: Gliclazide	1.0	1.2	2.7	0.8	1.1	1.0	1.0	1.3	0.7	1.3	1.2	0.4	1.6	1.1	1.2	0.6	1.0	1.1	1.0	1.5	0.9	0.9
Cardiovascular Disease	0.9	3.0	5.2	1.1	-2.0	-2.2	-1.7	-2.3	-1.6	-1.8	-1.9	-1.5	-2.0	-1.4	-2.2	-0.7	-1.9	-1.5	-1.5	-1.9	-1.8	-1.1
Sensitivity / hurt feelings	0.9	1.5	2.3	-0.8	-1.2	-1.1	-0.9	-1.4	-0.9	-1.2	-1.4	-0.9	-1.5	-1.3	-1.3	-1.1	-0.9	-1.4	-1.5	-1.5	-1.2	-1.1
Pack years adult smoking proportion	0.9	1.3	3.5	-0.1	-1.1	-1.5	-0.2	-1.6	-0.6	-0.3	-0.8	-1.4	-1.9	-0.7	-1.5	-0.2	-1.6	-1.1	-1.8	-1.5	-0.8	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.8	-1.7	-1.0	-1.0	-0.8	-1.3	-0.6	-1.3	-1.2	-0.6	-1.5	-1.2	-1.1	-0.7	-0.8	-1.3	-1.2	-1.5	-0.9	-0.8
Financial difficulties in last 2 years	0.9	1.2	4.3	0.7	-1.2	-1.1	-2.1	-0.4	-1.9	-0.2	-0.4	-1.0	-0.6	0.3	-0.9	-1.5	-1.1	-0.3	-0.6	-0.4	-1.6	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	2.8	0.2	-1.5	-1.5	-1.6	-1.3	-1.7	-1.4	-0.8	-0.2	-1.5	-0.3	-1.6	-0.4	-1.7	-0.6	-0.7	-1.1	-1.2	-1.1
Diabetes diagnosed by doctor	0.9	1.5	5.5	0.6	1.5	1.5	2.3	1.0	1.8	0.7	0.7	0.9	1.4	-0.1	1.4	1.0	1.6	0.2	0.2	1.0	1.5	1.3
Pain experienced in last month	0.9	1.5	3.3	-0.3	1.1	0.7	-0.1	1.4	1.0	1.8	0.9	-0.6	1.5	1.3	1.3	1.0	1.1	1.5	1.7	1.5	0.6	1.7
Bipolar Disorder or Schizophrenia	0.8	2.0	8.0	2.5	-0.4	-1.0	-0.7	0.6	-1.1	2.0	1.9	-0.1	0.3	2.8	-0.3	1.2	-1.8	2.1	1.2	1.2	0.1	0.4
Neuroticism (Nagel 2018)	0.8	1.8	4.5	-1.8	-1.3	-1.1	-1.7	-1.0	-1.5	-1.1	-1.4	-1.3	-0.9	-0.9	-1.1	-2.1	-0.7	-1.1	-1.1	-1.0	-1.7	-1.7
Hand grip strength (right)	0.8	2.1	6.0	0.4	1.4	1.0	0.7	1.8	0.9	2.4	1.6	-0.3	1.9	1.8	1.6	1.0	1.1	1.7	1.2	1.9	1.0	1.7
Medication: Lansoprazole	0.8	0.9	3.3	-0.0	-1.0	-0.3	-0.8	-0.7	-1.3	-1.6	-0.6	0.8	-0.9	-0.6	-0.9	-1.2	-0.7	-0.7	-0.5	-0.8	-0.8	-1.8
Headache pain in last month	0.8	1.4	4.3	-0.7	-1.0	-0.7	-0.5	-1.4	-0.8	-2.1	-1.4	0.3	-1.6	-1.5	-1.2	-0.5	-0.7	-1.4	-1.2	-1.6	-0.7	-1.2
Medication: Amlodipine	0.8	1.1	3.2	1.2	-0.4	-0.2	-0.5	-0.8	-0.2	-1.3	-1.6	-0.9	-0.9	-1.8	-0.5	-1.0	0.5	-1.6	-1.4	-1.3	-0.8	-0.4
Chronic bronchitis/emphysema (mother)	0.8	0.9	3.0	-1.0	-0.5	-0.3	0.4	-1.0	-0.1	-1.3	-1.3	-0.4	-0.6	-1.7	-0.6	-1.0	-0.0	-1.5	-1.3	-1.0	-0.5	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	4.2	2.0	0.3	0.1	0.4	0.8	-0.5	1.5	1.7	0.6	0.6	1.9	0.3	0.4	-0.7	1.3	0.4	1.1	0.5	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.6	1.0	1.1	1.0	1.2	1.0	1.0	1.2	0.9	0.3	1.0	0.6	1.1	0.6	1.0	0.7	0.5	0.9	1.0	1.0
Leg pain on walking	0.8	1.0	1.9	0.3	-1.2	-1.1	-1.3	-0.9	-1.2	-0.8	-0.9	-0.8	-0.7	-0.5	-1.0	-1.4	-1.1	-0.6	-0.5	-0.8	-1.3	-1.4
Medication: Aspirin	0.8	1.0	2.5	-0.8	-0.7	-0.6	-0.4	-1.1	-0.4	-1.2	-1.5	-1.0	-1.0	-1.6	-0.8	-0.9	-0.1	-1.5	-1.5	-1.3	-0.9	-0.6
Knee pain experienced in last month	0.8	1.2	2.4	-0.2	-1.0	-0.9	-1.0	-1.0	-1.3	-1.0	-1.3	-1.2	-1.0	-1.1	-1.0	-1.3	-0.6	-1.3	-1.6	-1.1	-1.3	-1.0
Guilty feelings	0.8	1.2	2.7	-1.0	-1.4	-1.3	-1.0	-1.2	-1.6	-1.0	-0.6	-0.3	-1.1	-0.2	-1.4	-0.7	-1.6	-0.6	-0.9	-0.9	-1.1	-1.3
Commuting to job workplace: Cycle	0.8	1.0	7.3	-2.7	-0.6	-0.6	0.2	-1.1	-0.1	-0.9	-0.9	-0.3	-0.9	-1.1	-0.8	-0.4	-0.7	-1.1	-1.1	-1.0	-0.4	-0.6
Frequency of depressed mood in last 2 weeks	0.7	0.9	1.8	-0.7	-1.1	-1.2	-1.3	-1.0	-1.1	-0.8	-0.9	-0.9	-1.3	-0.5	-1.1	-0.5	-1.0	-0.7	-0.7	-1.1	-1.1	-0.7
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.8	-0.7	-1.0	-1.1	-1.0	-0.9	-1.2	-0.5	-0.9	-1.4	-0.9	-0.5	-1.0	-1.0	-1.0	-0.8	-1.1	-0.8	-1.1	-0.8
Illnesses of siblings	0.7	1.0	3.9	0.6	-0.0	-0.5	-0.8	0.8	-0.6	2.0	1.2	-1.1	1.0	2.0	0.2	0.1	-0.6	1.4	0.7	1.3	-0.3	0.5
Impedance of arm (left)	0.7	3.1	13.4	-2.2	-1.9	-1.8	-3.7	-0.8	-2.8	-0.6	-1.1	-1.9	-1.5	0.1	-1.5	-1.8	-1.5	-0.3	-0.6	-1.1	-2.5	-1.6
Hair/balding pattern: Pattern 4	0.7	1.7	4.1	-0.1	1.6	1.0	1.4	1.3	1.8	1.8	1.2	-0.2	1.4	0.9	1.5	1.4	1.3	1.1	0.9	1.3	1.3	2.0
Leg fat mass (right)	0.7	2.6	14.8	3.9	1.1	1.1	1.7	0.9	1.1	0.4	1.6	2.4	1.3	1.2	0.9	2.0	0.4	1.4	1.6	1.4	1.7	1.0
Suffer from ‘nerves’	0.7	1.1	4.2	-2.0	-1.1	-0.9	-1.5	-0.8	-1.2	-1.2	-1.1	-0.9	-0.6	-0.7	-0.9	-1.2	-0.6	-0.7	-0.4	-0.7	-1.3	-1.2
Osteoporosis (self-reported)	0.7	0.8	2.5	-0.8	-0.6	-0.4	-0.4	-0.9	-0.4	-1.1	-0.9	-0.1	-1.6	-1.1	-0.7	-1.0	-0.4	-1.2	-1.2	-1.4	-0.6	-1.0
Medication: Aspirin	0.7	0.9	2.6	-0.7	-0.5	-0.5	-0.2	-1.0	-0.1	-1.0	-1.4	-1.2	-0.8	-1.6	-0.6	-1.0	0.1	-1.5	-1.5	-1.1	-0.8	-0.4
Hearing aid user	0.7	0.8	2.7	1.6	0.7	0.4	0.0	1.0	0.8	1.5	0.7	-0.6	1.0	0.9	0.9	0.3	0.7	1.0	1.0	1.0	0.3	0.9
Ever depressed for a whole week	0.7	0.9	1.8	0.5	-1.2	-1.1	-1.2	-1.1	-1.0	-1.0	-0.6	-0.1	-1.3	-0.3	-1.1	-0.7	-1.3	-0.4	-0.3	-1.0	-0.9	-1.3
Worry (Nagel 2018)	0.6	1.4	4.7	-1.9	-1.0	-0.8	-1.4	-0.6	-1.3	-0.9	-1.1	-1.2	-0.4	-0.8	-0.7	-2.2	-0.3	-0.9	-0.9	-0.6	-1.5	-1.6
Irritable Bowel Disease (IBD)	0.6	1.4	3.1	-0.9	-1.1	-1.1	-1.2	-1.1	-1.0	-0.9	-1.6	-1.8	-0.9	-1.3	-1.0	-1.4	-0.6	-1.4	-1.1	-1.2	-1.4	-0.9
BMI	0.6	3.3	22.5	4.7	1.3	1.2	2.0	0.9	1.6	0.5	1.4	2.0	1.7	1.0	1.1	2.4	0.8	1.3	1.6	1.5	1.9	1.7
Allergy or Eczema	0.6	1.5	4.7	-2.2	-0.5	-0.2	-0.2	-1.0	-0.0	-1.7	-1.8	-0.7	-1.1	-2.1	-0.6	-1.1	0.4	-1.9	-1.6	-1.5	-0.7	-0.7
Hair Pigment	0.6	18.4	29.3	-3.3	-4.2	-3.7	-3.1	-4.6	-3.3	-4.5	-4.8	-2.8	-4.6	-4.5	-4.3	-4.9	-3.0	-5.2	-5.4	-4.9	-4.3	-4.7
Tanning	0.6	6.9	12.0	3.2	3.2	3.0	3.3	2.5	3.5	2.1	2.0	1.8	2.4	0.9	3.0	2.4	3.1	1.6	1.9	2.1	3.1	3.0
Fed-up feelings	0.6	1.2	3.2	-0.3	-1.4	-1.6	-1.8	-1.0	-1.8	-0.7	-0.6	-0.8	-0.9	0.2	-1.4	-0.2	-1.6	-0.2	-0.5	-0.6	-1.4	-0.7
Age when periods started (menarche)	0.6	1.5	6.0	0.7	-0.9	-1.4	-1.0	-0.3	-1.5	1.0	1.5	0.4	-0.5	2.3	-1.0	1.1	-2.5	1.7	0.8	0.5	-0.3	-0.2
Trunk fat mass	0.6	2.7	15.6	4.0	1.1	1.1	1.6	1.1	1.0	0.6	1.7	2.3	1.5	1.4	1.0	2.0	0.4	1.5	1.6	1.5	1.6	1.1
Impedance of arm (right)	0.6	3.0	13.5	-1.8	-1.9	-1.8	-3.7	-0.9	-2.9	-0.8	-1.1	-1.6	-1.5	0.1	-1.6	-1.6	-1.6	-0.3	-0.5	-1.0	-2.5	-1.6
Father’s age at death	0.6	0.8	1.7	-0.6	1.1	1.1	0.4	1.2	1.2	1.0	0.6	0.2	0.8	0.6	1.2	0.8	1.3	0.7	1.0	0.7	0.9	1.2
Arm fat mass (right)	0.6	2.4	14.8	3.9	1.0	1.0	1.5	0.8	1.1	0.2	1.4	2.4	1.3	1.0	0.8	2.0	0.4	1.3	1.6	1.3	1.6	1.0
Number of full brothers	0.6	0.8	2.2	-0.1	-1.1	-1.0	-0.7	-1.0	-1.3	-0.9	-0.2	0.3	-1.0	-0.1	-1.2	-0.7	-1.5	-0.4	-0.7	-0.8	-0.8	-1.4
Number of self-reported non-cancer illnesses	0.6	1.0	3.8	-0.6	-0.9	-0.5	-0.3	-1.2	-0.4	-2.0	-1.2	0.5	-1.2	-1.4	-1.0	-0.5	-0.6	-1.2	-0.8	-1.4	-0.5	-1.0
Ever taken oral contraceptive pill	0.6	0.7	1.7	0.6	1.1	1.2	1.2	0.9	1.1	0.8	0.5	0.3	0.8	-0.0	1.1	0.0	1.3	0.1	-0.1	0.6	0.9	0.7
Medication: Blood pressure	0.6	1.2	2.9	1.1	-0.8	-0.8	-1.1	-1.1	-0.6	-1.4	-1.7	-1.3	-1.1	-1.6	-0.9	-0.6	-0.0	-1.5	-1.3	-1.3	-1.1	-0.2
Age started oral contraceptive pill	0.6	0.8	1.8	-0.0	0.9	0.8	0.8	0.9	1.1	0.8	0.9	0.6	0.9	0.8	1.0	0.6	0.7	1.2	1.4	1.0	1.0	0.7
Myopia	0.6	0.8	3.7	-1.9	-1.0	-0.8	-0.8	-0.9	-1.1	-1.2	-0.8	-0.0	-0.6	-0.6	-0.9	-0.8	-0.9	-0.6	-0.4	-0.7	-0.9	-1.2
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.4	0.5	1.0	1.1	1.9	0.4	1.4	0.1	0.5	1.2	0.3	-0.3	0.8	0.9	0.9	-0.2	-0.1	0.2	1.3	0.7
Pack years of smoking	0.6	0.9	2.4	-0.0	-0.8	-1.2	-0.2	-1.2	-0.4	-0.2	-0.7	-1.3	-1.5	-0.6	-1.1	-0.2	-1.1	-1.0	-1.6	-1.2	-0.6	-0.2
Leg fat mass (left)	0.6	2.5	13.8	3.7	1.1	1.2	1.8	0.9	1.2	0.4	1.5	2.4	1.4	1.1	1.0	1.9	0.5	1.3	1.5	1.3	1.7	0.9
Bipolar Disorder (2011)	0.5	0.5	2.5	0.8	-0.9	-0.8	-0.8	-0.1	-1.2	0.4	0.4	-0.2	-0.5	0.7	-0.8	-0.4	-1.6	0.0	0.0	-0.1	-0.7	-0.8
Blood Eosinophil Count	0.5	3.5	8.1	-2.8	-1.5	-1.5	-0.6	-2.2	-0.9	-2.2	-2.3	-1.4	-1.8	-2.4	-1.8	-1.2	-1.0	-2.5	-2.5	-2.2	-1.5	-1.2
Average weekly fortified wine intake	0.5	0.6	5.2	-0.6	-0.2	-0.6	-0.7	-0.3	-0.0	0.5	-1.0	-2.3	-0.5	-0.7	-0.2	-0.8	0.3	-0.8	-1.0	-0.6	-0.8	0.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.5	0.3	0.4	0.4	-0.5	1.1	-0.1	1.2	0.8	-0.3	1.1	1.1	0.8	-0.5	0.5	1.1	0.9	1.1	0.0	0.1
Hayfever, allergic rhinitis or eczema	0.5	1.2	4.5	-2.1	-0.3	-0.0	-0.0	-0.9	0.2	-1.7	-1.6	-0.3	-0.8	-2.0	-0.4	-0.7	0.5	-1.6	-1.1	-1.2	-0.4	-0.4
Supplements: Glucosamine	0.5	0.7	2.3	-0.3	-1.0	-1.0	-1.3	-0.4	-1.5	-0.1	0.3	0.0	-0.6	0.9	-0.9	-0.3	-1.5	0.6	0.3	-0.1	-0.7	-1.0
Heart attack	0.5	0.6	2.5	0.4	1.0	1.0	1.6	0.3	1.3	0.0	0.3	0.9	0.2	-0.4	0.7	0.6	1.0	-0.3	-0.2	0.0	1.1	0.6
Pain all over the body in last month	0.5	0.6	2.3	0.7	-0.3	0.0	0.6	-0.9	0.3	-1.5	-0.8	0.8	-0.6	-1.4	-0.4	-0.4	-0.1	-1.1	-0.6	-0.9	0.0	-0.8
Pulse rate	0.5	0.9	4.5	-0.1	-1.2	-1.3	-1.1	-0.7	-1.4	-0.1	0.4	0.3	-0.8	1.1	-1.2	-0.0	-2.1	0.7	0.4	-0.2	-0.7	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.9	1.0	-0.7	-0.6	-0.5	-0.9	-0.6	-0.7	-0.5	0.0	-1.4	-0.5	-0.9	-0.1	-0.8	-0.7	-0.7	-1.1	-0.4	-0.5
Exposure to tobacco smoke at home	0.5	0.6	2.3	1.0	0.8	0.9	1.2	0.5	0.8	-0.1	0.6	1.5	0.3	0.0	0.6	1.0	0.6	0.2	0.4	0.3	1.1	0.6
Tense / ‘highly strung’	0.5	0.8	3.8	-0.5	-0.8	-1.1	-1.0	-0.5	-1.1	0.3	-0.5	-1.9	-0.4	0.0	-0.7	-1.2	-0.8	-0.5	-1.1	-0.3	-1.2	-0.5
Loud music exposure frequency	0.5	0.5	1.0	1.0	0.6	0.3	0.6	0.5	0.8	0.8	0.7	0.1	0.5	0.7	0.5	1.0	0.3	0.8	0.8	0.6	0.7	1.0
Glaucoma (self-reported)	0.5	0.6	1.9	0.1	-0.9	-1.0	-1.0	-0.4	-1.4	0.2	0.2	-0.7	-0.4	0.7	-0.8	-0.7	-1.3	0.1	-0.5	-0.1	-0.9	-0.8
Comparative body size at age 10	0.5	1.5	6.7	-0.7	-1.0	-0.4	-0.2	-1.5	-0.4	-2.6	-1.3	1.3	-1.6	-1.7	-1.2	-0.3	-0.7	-1.3	-0.6	-1.7	-0.4	-1.3
Pulse wave peak to peak time	0.5	0.5	1.8	-0.0	0.7	0.3	0.4	0.7	0.7	1.3	0.3	-1.3	1.0	0.4	0.8	0.3	0.9	0.4	0.1	0.9	0.2	1.2
Whole body fat mass	0.5	2.2	13.8	3.7	0.9	0.9	1.4	0.8	0.9	0.4	1.5	2.2	1.2	1.1	0.8	1.9	0.3	1.3	1.4	1.3	1.5	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.2	-0.5	-0.7	-0.4	-0.3	-0.8	-0.6	-1.1	-0.8	-0.1	-1.1	-0.9	-0.7	-1.0	-0.5	-0.9	-0.8	-1.1	-0.6	-1.1
Back pain experienced in last month	0.5	0.8	2.4	-0.2	-0.8	-0.9	-0.5	-0.8	-0.6	-0.1	-0.9	-1.5	-1.0	-0.7	-0.8	-1.2	-0.6	-1.1	-1.5	-0.9	-0.9	-0.7
Osteoarthritis (self-reported)	0.5	0.6	1.7	-0.9	-0.5	-0.4	0.2	-1.0	-0.2	-1.3	-0.8	0.4	-1.2	-1.1	-0.8	-0.1	-0.5	-1.1	-1.0	-1.2	-0.2	-0.6
Arm fat mass (left)	0.5	1.9	13.7	3.7	0.7	0.8	1.3	0.6	0.8	0.0	1.2	2.2	1.1	0.9	0.6	1.8	0.1	1.1	1.4	1.1	1.3	0.7
Commuting to job workplace: Public transport	0.5	0.6	2.1	0.7	-0.0	-0.6	-0.6	0.4	-0.4	1.4	0.8	-0.9	0.6	1.4	0.0	0.9	-0.5	1.0	0.4	0.9	-0.2	0.9
Illnesses of father: High blood pressure	0.5	0.6	2.1	-0.1	-0.1	-0.3	0.6	-0.7	0.5	-0.4	-1.2	-1.4	-0.4	-1.4	-0.3	-0.5	0.3	-1.3	-1.2	-0.8	-0.3	0.1
Fractured/broken bones in last 5 years	0.5	0.7	3.6	-0.2	-0.3	0.2	0.8	-0.9	0.2	-1.9	-0.9	1.2	-0.5	-1.5	-0.5	-0.3	0.0	-1.1	-0.5	-0.9	0.1	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.1	0.5	-0.6	-0.4	-0.5	-0.7	-0.4	-0.9	-1.0	-0.4	-0.9	-1.0	-0.5	-1.1	-0.2	-1.0	-0.8	-1.0	-0.6	-0.9
Major Depression (MDD)	0.4	0.5	2.2	0.2	0.1	0.1	-0.2	0.4	-0.4	0.6	1.2	1.0	0.0	1.5	0.1	1.3	-0.6	1.2	0.8	0.6	0.5	0.4
Breast Cancer	0.4	0.9	2.3	-0.9	-1.3	-0.8	-1.1	-0.9	-1.2	-1.1	-0.8	-0.1	-0.6	-0.5	-1.1	-1.2	-1.1	-0.6	-0.5	-0.7	-1.2	-1.5
HbA1C	0.4	0.4	2.1	-1.5	-0.3	-0.1	0.1	-0.6	-0.2	-1.2	-0.8	-0.4	-0.5	-0.8	-0.4	-0.4	-0.0	-0.9	-0.9	-0.7	-0.2	-0.3
HDL Cholesterol	0.4	0.7	1.8	-1.0	-0.6	-0.7	0.3	-1.3	-0.3	-0.6	-0.7	-0.6	-1.1	-0.9	-0.9	-0.3	-0.7	-1.1	-1.3	-1.1	-0.4	-0.4
Waist Hip Ratio (WHR)	0.4	1.8	6.7	2.5	-0.2	-0.2	0.0	0.7	-1.1	1.2	2.2	1.4	0.5	2.6	-0.1	0.5	-1.6	2.0	1.2	1.3	0.4	-0.7
Ever had hysterectomy (womb removed)	0.4	0.5	1.6	1.3	-0.8	-0.6	-0.5	-0.6	-1.0	-0.7	-0.3	0.1	-0.7	-0.2	-0.8	-0.6	-0.8	-0.4	-0.7	-0.5	-0.6	-1.0
High blood pressure	0.4	1.2	2.9	1.2	-0.8	-0.8	-0.9	-1.1	-0.4	-1.4	-1.7	-1.2	-0.9	-1.6	-0.9	-0.6	-0.1	-1.4	-1.2	-1.3	-1.0	-0.3
Waist circumference	0.4	1.6	11.5	3.4	0.5	0.7	1.1	0.6	0.4	-0.1	1.3	2.3	0.9	1.0	0.5	1.3	-0.1	1.1	1.3	1.0	1.1	0.2
Medication: Ramipril	0.4	0.5	1.9	-0.1	0.6	0.8	0.9	0.0	0.9	-0.6	-0.7	0.1	0.0	-1.4	0.5	-0.4	1.3	-1.1	-0.7	-0.5	0.3	0.2
Asthma	0.4	0.8	2.0	0.8	0.9	0.8	1.4	0.7	1.1	0.7	0.9	0.9	0.8	0.6	0.8	0.9	0.6	0.8	0.7	0.8	1.2	0.7
Prospective memory result	0.4	0.5	1.4	1.2	0.9	0.8	1.0	0.5	1.1	0.5	0.3	0.4	0.1	-0.1	0.7	0.9	0.9	-0.0	-0.1	0.1	0.9	1.1
Birth weight of first child	0.4	0.7	2.3	0.2	0.4	-0.1	0.8	0.4	0.3	1.5	1.3	0.0	0.5	1.4	0.2	1.2	-0.6	1.1	0.4	0.9	0.7	0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.4	0.3	0.8	1.4	0.6	0.7	0.9	-0.7	-0.5	0.7	1.0	-1.1	1.0	-0.7	1.9	-0.5	0.3	0.3	0.4	-0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.0	0.8	0.6	0.6	0.5	0.7	0.5	0.5	0.6	0.5	1.0	0.6	0.7	0.5	0.6	0.8	0.8	0.9	0.6	0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.3	-0.4	-0.8	-0.6	-1.1	-0.7	-0.8	-1.1	-0.8	-0.1	-0.6	-0.6	-0.7	-0.4	-0.5	-0.5	-0.1	-0.7	-0.8	-0.7
Medication: Blood pressure	0.4	0.6	1.8	0.3	-0.4	-0.2	-0.5	-0.7	-0.3	-1.1	-1.2	-0.6	-0.8	-1.3	-0.5	-0.9	0.2	-1.3	-1.0	-1.0	-0.7	-0.5
Smoking status: Previous	0.4	0.6	3.0	-0.2	1.0	1.3	0.9	0.6	1.0	-0.4	-0.3	0.6	0.4	-0.9	1.0	-0.1	1.7	-0.5	-0.0	0.0	0.7	0.5
Long-standing illness, disability or infirmity	0.4	0.6	1.5	-0.1	-0.6	-0.4	0.2	-1.0	-0.0	-1.1	-1.0	-0.1	-1.1	-1.2	-0.7	-0.6	-0.4	-1.1	-1.1	-1.2	-0.3	-0.8
Smoking status: Current	0.4	0.6	2.5	1.1	-0.2	-0.5	-0.7	0.3	-0.5	1.1	1.0	0.0	-0.2	1.6	-0.2	0.7	-1.0	1.2	0.7	0.5	0.0	0.3
Heart disease (siblings)	0.4	0.5	1.4	0.7	-0.8	-0.7	-0.3	-0.9	-0.8	-0.9	-0.2	0.5	-1.0	-0.2	-0.9	-0.0	-1.2	-0.3	-0.4	-0.8	-0.3	-0.9
Alcohol drinker status: Previous	0.4	0.4	1.5	0.3	0.7	0.5	1.2	0.4	0.8	0.7	0.8	0.6	0.2	0.5	0.5	1.0	0.2	0.4	0.1	0.4	1.0	0.8
Alzheimer’s Disease (in father)	0.3	0.4	2.2	1.5	0.5	0.3	0.9	0.4	0.7	0.6	0.5	0.1	0.6	0.4	0.5	0.5	0.3	0.4	0.3	0.6	0.6	0.7
Crohns Disease (2012)	0.3	0.6	1.5	-1.2	-0.7	-0.5	-0.7	-0.8	-0.9	-0.7	-0.7	-0.6	-0.6	-0.7	-0.7	-0.8	-0.4	-0.9	-1.0	-0.7	-0.7	-0.6
Rheumatoid Arthritis	0.3	0.3	1.4	0.6	0.7	0.7	0.4	0.6	1.0	0.2	-0.2	-0.2	0.7	-0.3	0.8	0.0	1.2	0.2	0.6	0.4	0.4	0.6
Heel T-Score	0.3	2.2	5.4	0.6	1.4	1.6	1.1	1.7	1.0	0.9	1.4	1.5	2.3	1.3	1.6	1.2	1.4	1.6	2.0	2.0	1.4	1.1
Supplements: Zinc	0.3	0.4	1.2	0.7	0.0	0.1	-0.4	-0.2	0.3	-0.3	-1.0	-1.0	-0.6	-1.1	0.1	-0.9	0.7	-0.7	-0.4	-0.7	-0.4	-0.2
Taking other prescription medications	0.3	0.5	1.6	0.8	0.8	1.0	1.3	0.4	1.1	-0.1	0.3	1.0	0.2	-0.3	0.7	0.6	0.9	0.0	0.2	0.1	1.0	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	0.7	0.7	0.7	0.3	1.0	0.5	0.7	0.8	0.5	1.4	0.9	0.8	0.8	0.7	1.0	1.2	1.2	0.6	0.8
Qualifications: CSEs or equivalent	0.3	0.4	1.3	-1.0	-0.6	-0.9	0.2	-0.8	-0.5	0.1	-0.4	-0.9	-0.4	-0.2	-0.8	-0.0	-0.9	-0.5	-1.1	-0.3	-0.4	-0.0
Body mass index (BMI)	0.3	1.4	9.7	3.1	0.5	0.7	1.5	0.1	0.9	-0.8	0.6	2.5	0.6	0.1	0.3	1.6	0.1	0.5	1.1	0.4	1.3	0.3
Number of incorrect matches in round	0.3	0.5	2.1	1.4	0.9	1.0	0.8	0.6	0.8	0.3	0.2	0.4	0.3	-0.2	0.8	0.5	1.1	0.0	0.2	0.2	0.8	0.9
Arm fat percentage (right)	0.3	1.0	8.4	2.9	-0.2	0.1	0.1	-0.2	-0.1	-1.1	0.5	2.3	0.2	0.4	-0.2	1.1	-0.5	0.6	1.2	0.2	0.5	-0.3
Number of live births	0.3	0.4	5.0	2.2	0.1	0.2	0.9	-0.1	0.3	-0.2	0.4	1.1	-0.0	0.1	-0.0	0.5	-0.3	0.0	0.1	-0.0	0.6	-0.1
Pulse wave Arterial Stiffness index	0.3	0.4	1.4	0.1	-0.5	-0.1	-0.2	-0.5	-0.5	-1.1	-0.2	1.2	-0.8	-0.3	-0.6	-0.2	-0.7	-0.4	-0.2	-0.7	-0.1	-1.0
Blood clot in the leg (DVT)	0.3	0.4	1.1	0.6	-0.6	-0.5	0.2	-0.6	-0.5	-0.6	-0.5	-0.4	-0.3	-0.6	-0.6	-0.9	-0.5	-0.8	-1.1	-0.4	-0.5	-0.9
Angina (self-reported)	0.3	0.4	3.1	1.8	0.4	0.3	-0.2	0.7	-0.1	0.7	0.7	0.2	0.6	0.8	0.5	0.2	0.3	0.7	0.6	0.7	0.2	0.4
Medication: Omeprazole	0.3	0.3	0.9	-0.1	-0.4	-0.0	-0.1	-0.5	-0.1	-0.9	-0.6	0.3	-0.8	-0.8	-0.3	-0.8	-0.1	-0.7	-0.5	-0.8	-0.2	-0.9
Hypertension (Self-reported)	0.3	0.9	3.0	1.2	-0.4	-0.4	-0.3	-0.9	0.0	-1.4	-1.6	-0.9	-0.7	-1.7	-0.5	-0.3	0.4	-1.5	-1.1	-1.1	-0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.2	1.1	0.9	0.6	1.4	0.7	0.8	1.5	0.9	-0.2	0.8	0.6	0.8	0.6	0.6	0.3	-0.3	0.9	0.8	1.0
Arm fat percentage (left)	0.3	1.0	8.4	2.9	-0.1	0.2	0.2	-0.0	-0.1	-1.0	0.6	2.3	0.3	0.5	-0.1	1.2	-0.5	0.7	1.3	0.4	0.6	-0.3
Qualifications: nursing, teaching	0.3	0.4	1.7	-0.5	0.4	0.7	0.8	-0.1	0.7	-0.7	-0.7	0.2	0.0	-1.3	0.3	-0.7	1.0	-1.1	-0.8	-0.4	0.2	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.2	0.3	-0.7	-0.5	-0.4	-0.8	-0.4	-1.1	-0.4	0.7	-1.1	-0.5	-0.7	-0.3	-0.8	-0.4	-0.1	-0.9	-0.3	-1.0
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.5	0.1	-0.7	-0.4	-0.5	-0.4	-1.2	-0.8	-0.2	0.3	-0.3	-0.1	-0.6	-0.7	-0.7	-0.5	-0.6	-0.3	-0.6	-1.1
Diastolic blood pressure, automated reading	0.3	1.0	5.4	-0.7	-0.6	0.1	-0.7	-0.8	-0.2	-2.3	-1.4	0.8	-0.9	-1.6	-0.6	-0.7	0.3	-1.2	-0.3	-1.2	-0.5	-1.1
Unable to work because of sickness or disability	0.3	0.4	1.6	0.6	-0.6	-0.8	-0.8	-0.1	-1.0	0.6	0.7	0.0	-0.1	1.2	-0.5	0.0	-1.3	0.8	0.4	0.3	-0.4	-0.5
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.0	-1.0	0.5	0.6	0.7	0.9	0.2	1.2	1.4	1.0	0.8	1.4	0.6	0.5	-0.1	1.3	1.0	1.1	0.8	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.7	-0.9	-0.6	-0.3	-1.6	0.0	-0.7	-0.6	-0.9	-0.8	-0.2	-0.4	-0.3	-1.2	0.1	-0.3	-0.0	-0.3	-1.1	-0.7
Alzheimer’s Disease (in mother)	0.2	0.2	1.0	0.9	-0.3	0.1	-0.8	-0.1	-0.4	-1.0	-0.5	0.5	0.1	-0.4	-0.1	-0.4	0.2	-0.1	0.6	-0.2	-0.4	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.5	2.1	-1.0	-0.4	-0.3	-1.5	0.0	-0.7	-0.4	-0.8	-1.2	0.2	-0.4	-0.1	-1.1	0.4	-0.3	-0.0	-0.1	-1.1	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.7	-0.3	0.5	0.6	0.3	0.7	0.4	-0.0	0.1	0.3	0.9	0.0	0.5	0.5	0.7	0.2	0.6	0.5	0.3	0.6
Mean Putamen Volume	0.2	0.2	0.6	-0.1	0.5	0.3	-0.2	0.7	0.3	0.8	0.2	-0.8	0.3	0.3	0.6	0.2	0.6	0.4	0.4	0.4	0.1	0.8
LDL Cholesterol	0.2	0.3	1.2	-0.4	0.0	-0.1	-0.6	0.2	-0.2	0.6	0.7	0.3	0.1	1.1	0.1	0.7	-0.3	1.0	0.7	0.5	0.1	0.3
Lupus	0.2	0.3	1.1	0.1	0.0	0.2	0.6	-0.4	0.3	-0.9	-0.6	0.2	-0.4	-1.1	-0.1	-0.3	0.3	-1.0	-0.7	-0.6	0.1	-0.3
Hypothyroidism (self reported)	0.2	0.5	2.8	1.7	0.8	0.6	0.6	0.5	1.0	0.4	0.3	0.3	0.4	0.1	0.7	1.1	0.8	0.4	0.6	0.4	0.7	1.1
Hearing difficulty/problems: Yes	0.2	0.4	2.1	1.5	0.6	0.4	0.4	0.6	0.5	0.5	0.2	-0.2	0.8	0.2	0.6	0.4	0.7	0.4	0.4	0.6	0.3	0.8
Relative age of first facial hair	0.2	0.4	1.8	-1.0	-0.6	-0.5	-1.3	-0.2	-1.0	-0.3	-0.3	-0.3	-0.3	0.1	-0.4	-0.6	-0.5	0.0	0.2	-0.2	-0.8	-0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.9	0.6	-0.0	-0.3	-0.5	0.3	-0.3	0.9	0.4	-0.8	-0.0	0.8	0.0	0.0	-0.2	0.4	-0.2	0.3	-0.2	0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	0.6	0.6	0.7	0.8	0.2	0.7	-0.1	-0.1	0.3	0.3	-0.4	0.5	0.4	0.9	-0.2	-0.0	0.1	0.5	0.6
Angina	0.2	0.3	2.5	1.6	0.3	0.3	-0.3	0.6	-0.1	0.6	0.5	0.1	0.6	0.7	0.4	0.1	0.3	0.6	0.5	0.6	0.1	0.3
Diabetes (father)	0.2	0.3	1.2	0.4	0.6	0.5	0.9	0.2	1.1	0.3	0.3	0.4	0.1	0.0	0.5	0.8	0.5	0.1	0.3	0.1	0.8	0.8
Trunk fat percentage	0.2	0.7	6.9	2.6	-0.2	0.1	0.1	-0.0	-0.4	-0.8	0.5	1.9	0.2	0.4	-0.2	0.7	-0.5	0.5	0.8	0.3	0.3	-0.4
Current tobacco smoking	0.2	0.4	1.4	0.7	-0.4	-0.8	-0.7	-0.1	-0.6	0.8	0.7	-0.1	-0.4	1.2	-0.4	0.7	-1.1	0.9	0.5	0.2	-0.1	0.2
Relative age voice broke	0.2	0.3	1.3	0.0	0.7	0.9	0.2	0.9	0.3	0.3	0.2	0.0	0.7	0.1	0.8	-0.3	1.1	0.1	0.2	0.5	0.3	0.3
Medication: Atenolol	0.2	0.2	3.0	1.7	0.2	0.3	-0.3	0.2	-0.0	-0.1	-0.1	-0.0	0.1	-0.2	0.2	0.0	0.6	-0.2	-0.1	0.0	-0.1	0.3
Past tobacco smoking	0.2	0.3	1.7	0.4	-0.6	-0.9	-0.4	-0.4	-0.6	0.4	0.4	-0.2	-0.0	0.8	-0.6	0.5	-1.3	0.6	0.3	0.2	-0.3	-0.1
Nervous feelings	0.2	0.4	1.8	-1.1	-0.3	-0.2	-0.8	-0.1	-0.3	-0.2	-0.8	-1.3	0.1	-0.5	-0.0	-1.2	0.4	-0.4	-0.4	-0.1	-0.8	-0.4
Hearing difficulty/problems with background noise	0.2	0.4	1.7	-0.4	0.5	0.7	0.4	0.2	0.9	-0.6	-0.7	0.0	0.3	-1.1	0.5	-0.0	1.3	-0.6	-0.0	-0.2	0.2	0.5
Forced vital capacity (FVC)	0.2	0.8	3.7	0.0	0.6	0.0	0.3	0.8	0.2	1.9	1.1	-0.7	1.0	1.4	0.6	0.9	0.0	1.0	0.4	1.2	0.4	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.9	0.5	0.7	0.7	0.2	0.8	0.5	0.4	0.4	0.3	0.9	0.4	0.7	0.7	0.8	0.5	0.7	0.8	0.5	0.8
Allergy	0.2	0.6	2.0	1.4	0.4	0.2	-0.1	0.8	-0.2	1.3	1.0	-0.0	0.7	1.3	0.5	0.5	0.0	1.0	0.7	0.9	0.2	0.6
Length of working week for main job	0.2	0.2	0.7	-0.4	-0.2	-0.3	0.1	-0.6	0.1	-0.6	-0.7	-0.5	-0.6	-0.8	-0.4	-0.1	-0.0	-0.8	-0.7	-0.7	-0.2	-0.0
Breastfed as a baby	0.2	0.3	1.0	-0.9	-0.1	0.1	0.2	-0.4	-0.1	-0.8	-0.6	-0.0	-0.4	-1.0	-0.2	-0.6	0.2	-1.0	-0.9	-0.6	-0.2	-0.4
Birth weight	0.2	0.4	1.0	-0.2	-0.4	-0.5	0.4	-1.0	0.2	-0.7	-0.7	-0.2	-1.0	-1.0	-0.7	-0.0	-0.5	-1.0	-1.0	-1.0	-0.1	-0.2
Forced vital capacity (FVC), Best measure	0.2	0.6	2.3	0.2	0.5	0.1	0.2	0.7	0.3	1.5	0.9	-0.5	0.8	1.1	0.5	0.9	0.1	0.9	0.4	1.0	0.3	1.1
Body fat percentage	0.2	0.7	6.6	2.6	-0.4	-0.1	-0.1	-0.3	-0.6	-0.9	0.4	1.7	-0.0	0.4	-0.4	0.7	-0.8	0.5	0.8	0.1	0.2	-0.6
Leg fat percentage (right)	0.2	0.7	4.5	2.1	-0.6	-0.3	0.0	-0.7	-0.6	-1.3	0.1	1.7	-0.5	0.1	-0.8	0.5	-1.1	0.1	0.4	-0.3	0.1	-0.8
Number of children fathered	0.2	0.3	0.5	0.3	-0.6	-0.5	-0.6	-0.4	-0.7	-0.4	-0.3	-0.4	-0.5	-0.1	-0.5	-0.7	-0.7	-0.2	-0.3	-0.4	-0.6	-0.7
Age at first live birth	0.2	0.4	1.6	-1.0	-0.1	0.3	0.1	-0.2	0.3	-0.8	-0.8	-0.1	-0.1	-1.1	0.1	-1.3	0.5	-0.9	-0.4	-0.5	-0.3	-0.9
Emphysema/chronic bronchitis	0.2	0.3	1.9	0.3	-0.4	-0.8	-1.0	-0.2	-0.3	0.5	-0.3	-1.4	-0.2	0.2	-0.3	-0.2	-0.4	0.1	0.1	-0.1	-0.6	0.2
Neck or shoulder pain in last month	0.2	0.2	1.3	0.4	-0.3	-0.3	0.3	-0.6	-0.1	-0.2	-0.3	-0.2	-0.8	-0.4	-0.5	0.0	-0.4	-0.8	-1.1	-0.7	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.5	0.3	0.6	0.7	0.4	0.7	0.5	0.6	0.4	0.3	0.2	0.3	0.7	0.0	0.6	0.5	0.6	0.3	0.6	0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.8	0.1	0.1	-0.3	0.4	-0.2	0.4	0.6	0.4	0.5	0.8	0.2	0.5	-0.1	0.7	0.6	0.6	0.1	0.3
Commuting to job workplace: Walk	0.2	0.2	1.4	-1.2	0.1	0.1	-0.2	-0.1	0.4	-0.2	-0.6	-0.7	-0.2	-0.7	0.1	-0.3	0.6	-0.6	-0.4	-0.4	-0.2	0.3
Breast cancer (self-reported)	0.2	0.2	1.3	-0.5	-0.0	0.2	-0.1	-0.0	0.3	-0.2	-0.6	-0.7	-0.1	-0.7	0.2	-1.1	0.5	-0.5	-0.3	-0.3	-0.3	-0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	0.6	-0.6	-0.2	-0.5	-0.4	-0.7	-0.8	-0.3	0.3	-0.2	-0.2	-0.5	-0.6	-0.4	-0.3	-0.3	-0.3	-0.5	-0.9
Medication: Lisinopril	0.2	0.2	2.2	-0.1	-0.1	-0.4	-0.4	-0.1	-0.2	0.6	-0.4	-1.5	0.3	-0.1	-0.1	-0.4	0.1	-0.3	-0.6	0.1	-0.6	0.3
Ever smoked	0.2	0.3	0.9	-0.9	0.2	0.4	-0.1	-0.0	0.3	-0.5	-0.7	-0.3	-0.4	-0.9	0.2	-0.6	0.8	-0.7	-0.5	-0.6	-0.1	-0.1
Leg fat percentage (left)	0.2	0.6	4.2	2.0	-0.6	-0.2	0.1	-0.6	-0.6	-1.3	0.1	1.6	-0.4	-0.1	-0.7	0.3	-0.9	-0.0	0.3	-0.3	0.1	-0.9
Irritability	0.2	0.3	2.4	0.1	0.1	-0.2	-0.4	0.3	-0.2	0.8	-0.2	-1.6	0.5	0.2	0.2	-0.5	0.3	0.1	-0.3	0.5	-0.5	0.3
Risk taking	0.2	0.4	2.5	1.5	-0.1	0.3	0.1	0.1	-0.4	-0.5	0.5	1.6	-0.0	0.4	-0.1	-0.0	-0.4	0.4	0.5	0.2	0.3	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	0.5	-0.4	-0.4	0.1	-0.4	-0.4	-0.3	-0.3	-0.6	-0.1	-0.4	-0.4	-0.8	-0.4	-0.6	-0.9	-0.2	-0.5	-0.6
Alzheimer’s Disease (including proxy)	0.1	0.2	2.2	1.5	0.1	0.2	-0.1	0.1	0.1	-0.1	-0.1	0.3	0.4	0.1	0.2	-0.1	0.3	0.1	0.5	0.2	-0.0	-0.1
Crohns Disease (2017)	0.1	0.1	0.7	-0.8	-0.3	-0.4	-0.4	-0.3	-0.6	0.0	-0.3	-0.5	-0.0	-0.1	-0.3	-0.5	-0.3	-0.3	-0.2	-0.2	-0.4	-0.3
Ovarian Cancer	0.1	0.2	0.7	-0.5	-0.2	0.1	0.5	-0.3	-0.2	-0.8	-0.3	0.6	0.3	-0.5	-0.2	-0.4	-0.0	-0.4	-0.2	-0.0	-0.0	-0.7
Body Mass Index (BMI) (2010)	0.1	0.2	1.5	1.2	0.0	0.2	-0.6	0.5	-0.1	-0.0	-0.1	-0.2	0.4	0.1	0.3	-0.4	0.4	0.2	0.5	0.2	-0.3	-0.2
Primary Biliary Cirrhosis	0.1	0.1	0.4	0.6	0.4	0.5	0.3	0.4	0.2	0.2	0.3	0.5	0.2	0.1	0.4	0.1	0.4	0.1	0.1	0.2	0.3	0.2
Blood Red Count	0.1	1.2	3.7	-0.2	-0.8	-0.5	-0.1	-1.4	0.0	-1.9	-1.4	0.1	-1.4	-1.8	-1.0	-0.6	-0.4	-1.5	-1.0	-1.6	-0.5	-1.0
Smoking Status	0.1	0.2	1.3	1.1	0.2	0.2	-0.3	0.4	-0.2	0.5	0.5	0.4	0.0	0.7	0.2	0.4	0.0	0.6	0.4	0.3	0.2	0.2
Respiratory disease	0.1	0.3	0.6	0.2	0.4	0.2	0.4	0.5	0.5	0.7	0.5	0.0	0.6	0.6	0.5	0.6	0.2	0.8	0.7	0.7	0.5	0.7
Lung FEV1/FVC ratio	0.1	0.5	2.8	1.7	-0.4	-0.3	-0.8	0.3	-1.1	0.6	0.7	0.1	0.3	1.1	-0.2	-0.7	-0.8	0.5	0.3	0.5	-0.5	-0.8
Lung FVC	0.1	0.6	2.4	-1.1	-0.7	-0.4	-0.3	-0.7	-0.6	-1.2	0.1	1.6	-0.5	0.2	-0.7	0.3	-1.1	0.4	0.7	-0.3	-0.1	-1.0
Severe depression (siblings)	0.1	0.1	0.5	-0.5	0.2	0.2	0.7	-0.2	0.6	-0.1	-0.4	-0.3	-0.3	-0.6	0.1	0.1	0.3	-0.5	-0.5	-0.4	0.3	0.3
Medication: Levothyroxine sodium	0.1	0.2	0.7	0.2	-0.0	0.0	0.3	-0.4	0.2	-0.8	-0.5	0.2	-0.4	-0.8	-0.2	0.1	0.2	-0.7	-0.7	-0.6	0.0	0.0
Chronic bronchitis/emphysema (father)	0.1	0.2	0.7	0.5	-0.2	-0.1	0.6	-0.5	0.2	-0.4	0.1	0.9	-0.4	-0.1	-0.3	0.5	-0.6	-0.0	0.1	-0.3	0.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.6	0.4	-0.5	-0.5	-0.8	-0.5	-0.3	-0.5	-0.6	-0.5	-0.6	-0.4	-0.5	-0.4	-0.3	-0.4	-0.3	-0.6	-0.5	-0.4
Fluid intelligence score	0.1	0.1	1.3	-1.2	-0.1	0.0	-0.6	0.0	-0.2	-0.5	-0.4	-0.1	0.1	-0.3	0.0	-0.4	0.3	-0.1	0.3	-0.1	-0.3	-0.2
Hip circumference	0.1	0.5	2.8	1.7	0.2	0.4	0.9	-0.3	0.6	-1.1	-0.1	1.5	0.3	-0.6	-0.0	0.8	0.2	-0.3	0.2	-0.0	0.6	0.1
Worrier / anxious feelings	0.1	0.3	0.9	-0.9	0.5	0.7	0.7	0.3	0.6	-0.3	-0.2	0.3	0.7	-0.5	0.5	-0.5	0.9	-0.3	-0.1	0.3	0.3	-0.1
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.6	0.3	0.1	-0.2	0.4	0.4	0.5	0.4	-0.1	0.5	0.5	0.4	0.5	0.2	0.6	0.6	0.5	0.2	0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.7	0.1	-0.2	-0.6	-0.4	0.3	-0.8	1.3	0.7	-0.8	0.5	1.3	-0.1	0.1	-0.7	0.7	0.0	0.8	-0.3	0.2
Noisy workplace	0.1	0.1	0.4	-0.3	0.2	0.3	-0.1	0.4	0.1	0.2	0.3	0.3	-0.0	0.4	0.3	0.3	0.2	0.5	0.6	0.1	0.3	0.2
Depression (self-reported)	0.1	0.1	0.2	-0.3	-0.0	0.2	0.5	0.0	-0.3	-0.2	0.1	0.4	0.3	-0.1	-0.0	-0.4	0.0	-0.3	-0.5	0.1	0.1	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	1.1	0.3	0.0	-0.3	-0.1	0.3	-0.2	1.1	0.6	-0.5	0.5	0.9	0.1	0.3	-0.3	0.6	0.1	0.7	-0.1	0.4
Peak expiratory flow (PEF)	0.1	0.3	1.0	-0.1	-0.5	-0.8	-0.4	-0.3	-0.8	0.8	0.3	-0.9	-0.1	0.6	-0.5	-0.2	-1.0	0.2	-0.4	0.1	-0.5	-0.2
Pulse wave reflection index	0.1	0.1	0.4	0.6	-0.1	0.1	-0.0	-0.1	-0.1	-0.2	0.2	0.6	-0.4	0.1	-0.1	0.1	-0.2	0.0	0.0	-0.2	0.1	-0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.7	0.6	0.3	-0.0	0.0	0.1	0.3	0.4	0.1	-0.3	-0.1	0.2	0.1	0.8	0.2	0.2	-0.0	0.0	0.2	0.8
Worry too long after embarrassment	0.1	0.1	1.1	-0.5	-0.3	-0.2	-1.0	-0.0	-0.5	-0.4	-0.2	-0.2	0.1	0.1	-0.2	-0.2	-0.0	0.1	0.3	0.0	-0.5	-0.1
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	-0.1	-0.1	-0.2	0.6	-0.2	0.4	-0.1	0.3	0.5	0.3	0.3	-0.1	0.7	-0.5	0.6	0.7	0.4	0.4	0.1
Shortness of breath walking on level ground	0.1	0.1	0.4	-0.6	-0.3	-0.2	-0.5	-0.2	-0.4	-0.3	-0.4	-0.4	-0.3	-0.2	-0.2	-0.6	-0.1	-0.2	-0.2	-0.3	-0.4	-0.5
Qualifications: College or University degree	0.1	0.5	1.8	-0.5	0.8	1.1	0.6	0.9	0.9	0.2	0.1	0.3	0.9	-0.3	1.0	-0.6	1.4	-0.0	0.3	0.5	0.4	0.0
Age at last live birth	0.1	0.2	0.9	-0.4	-0.3	0.0	0.0	-0.3	0.0	-0.6	-0.1	0.7	-0.3	-0.4	-0.2	-0.7	-0.2	-0.2	0.2	-0.4	-0.1	-1.0
Family relationship satisfaction	0.1	0.2	0.9	-0.9	-0.2	0.1	-0.4	-0.1	-0.3	-0.6	-0.0	0.6	-0.2	-0.1	-0.1	-0.5	-0.1	0.0	0.3	-0.2	-0.2	-0.7
Ever had bowel cancer screening	0.1	0.1	1.0	0.3	0.3	0.5	1.0	0.1	0.3	-0.1	0.0	0.4	0.2	-0.4	0.2	-0.3	0.3	-0.4	-0.4	0.1	0.4	-0.3
Asthma (self-reported)	0.1	0.3	1.3	0.2	0.6	0.5	1.1	0.3	0.8	0.2	0.5	0.6	0.5	0.1	0.5	0.5	0.3	0.4	0.4	0.4	0.8	0.4
Illnesses of father: None of the above (group 1)	0.1	0.2	0.8	-0.1	0.3	0.4	-0.4	0.5	0.1	-0.1	-0.1	0.2	0.9	-0.0	0.5	-0.0	0.8	0.2	0.7	0.6	-0.0	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.4	0.6	0.2	0.2	0.1	0.4	0.1	0.5	0.2	-0.1	0.6	0.3	0.3	-0.3	0.2	0.3	0.4	0.5	0.0	-0.1
Wears glasses or contact lenses	0.1	0.1	0.7	-0.8	0.2	0.4	0.4	0.1	0.4	-0.4	-0.1	0.8	0.2	-0.3	0.3	-0.1	0.4	0.0	0.5	0.0	0.4	-0.2
Eye problems/disorders: Glaucoma	0.1	0.2	0.6	-0.1	-0.2	-0.4	-0.2	0.0	-0.5	0.6	0.6	-0.3	-0.1	0.8	-0.2	-0.1	-0.7	0.4	-0.1	0.2	-0.2	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.4	0.5	0.1	0.3	0.3	0.0	0.1	-0.4	-0.0	0.6	0.1	-0.3	0.1	0.0	0.2	-0.2	0.1	-0.1	0.2	-0.1
Qualifications: None of the above	0.0	0.1	0.3	0.2	-0.2	-0.1	-0.3	-0.1	-0.3	-0.3	0.1	0.5	-0.5	0.1	-0.2	0.2	-0.3	0.0	0.2	-0.3	0.0	-0.2

Hub : Genes

C2orf28

Models

Trait associations