TWAS hub - C2orf54

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0960	0.0640	4.5e-03	0.013	0.020	0.026	NA	0.031	2.5e-02	8.0e-03	2.8e-03	NA	1.1e-03
2	TCGA	Breast Invasive Carcinoma	0.0926	0.0317	0.0e+00	0.103	0.078	0.088	NA	0.097	2.9e-20	1.0e-15	1.8e-17	NA	3.1e-19
3	TCGA	Colon Adenocarcinoma	0.0810	0.0460	1.7e-03	0.029	0.013	0.012	NA	0.021	8.4e-03	5.4e-02	6.0e-02	NA	2.1e-02
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.1787	0.0512	0.0e+00	0.231	0.204	0.205	NA	0.222	1.1e-25	1.6e-22	1.2e-22	NA	1.5e-24
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3340	0.1270	4.9e-13	0.268	0.229	0.208	NA	0.268	1.3e-15	2.6e-13	4.2e-12	NA	1.4e-15
6	TCGA	Liver Hepatocellular Carcinoma	0.2870	0.0930	8.9e-13	0.312	0.222	0.318	NA	0.002	3.1e-15	9.2e-11	1.5e-15	NA	2.4e-01
7	TCGA	Lung Adenocarcinoma	0.1538	0.0547	1.9e-12	0.113	0.117	0.116	NA	0.106	3.7e-13	1.6e-13	2.1e-13	NA	2.4e-12
8	TCGA	Lung Squamous Cell Carcinoma	0.1278	0.0496	7.1e-06	0.022	0.050	0.045	NA	0.032	1.4e-03	2.0e-06	7.2e-06	NA	1.4e-04
9	TCGA	Prostate Adenocarcinoma	0.4076	0.0818	0.0e+00	0.374	0.387	0.393	NA	0.400	3.8e-41	8.4e-43	1.2e-43	NA	1.1e-44
10	TCGA	Stomach Adenocarcinoma	0.1580	0.0660	1.2e-05	0.051	0.026	0.032	NA	0.018	1.4e-04	5.2e-03	2.1e-03	NA	1.7e-02
11	TCGA	Thyroid Carcinoma	0.4860	0.1010	0.0e+00	0.248	0.277	0.281	NA	0.263	5.0e-24	4.3e-27	1.7e-27	NA	1.5e-25

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Lung FVC	8.1	41.2	54.0	3.6	7.3	7.2	7.2	7.3	7.3	6.2	3.0	7.2	6.9	5.3
Forced vital capacity (FVC), Best measure	6.8	24.8	35.4	3.1	5.7	5.7	5.6	6.0	5.8	4.6	2.1	5.5	5.0	4.1
Forced vital capacity (FVC)	5.9	22.7	32.9	2.8	5.5	5.5	5.4	5.7	5.5	4.2	1.7	5.3	5.0	3.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	5.3	11.2	15.5	3.4	3.8	3.8	3.7	3.9	3.5	2.7	1.6	3.6	3.0	3.0
Commuting to job workplace: Car/motor vehicle	4.7	5.3	6.4	2.3	2.5	2.5	2.5	2.5	2.5	2.2	1.4	2.5	2.0	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	4.4	14.0	20.0	2.5	4.3	4.3	4.2	4.5	4.3	3.4	1.6	4.2	3.8	3.1
Medication: Lansoprazole	4.0	4.5	7.2	1.5	2.2	2.2	2.3	2.2	2.3	2.0	1.3	2.3	2.0	2.7
Tinnitus: Yes, but not now, but have in the past	3.9	4.2	7.1	-1.6	-2.2	-2.2	-2.2	-2.2	-1.9	-1.6	-1.8	-1.9	-1.9	-2.7
Number of self-reported non-cancer illnesses	3.9	6.8	12.7	3.6	2.7	2.8	2.7	3.0	2.8	2.3	1.0	2.7	1.4	2.6
Fractured/broken bones in last 5 years	3.8	4.9	6.8	2.2	2.2	2.2	2.2	2.0	2.1	2.6	2.6	2.2	1.7	2.3
Pain experienced in last month	3.8	6.4	9.0	-1.9	-2.6	-2.5	-2.6	-2.4	-2.5	-3.0	-2.5	-2.6	-2.9	-2.2
Hip circumference	3.6	15.3	22.2	4.1	4.4	4.5	4.3	4.7	4.0	3.6	2.2	4.0	3.4	3.1
Angina	3.2	4.2	5.7	1.5	2.2	2.2	2.2	2.4	2.4	2.0	1.3	2.3	1.6	2.1
Angina (self-reported)	3.2	4.2	5.6	1.4	2.2	2.2	2.2	2.3	2.4	2.1	1.5	2.2	1.5	2.2
Number of treatments/medications taken	3.1	5.5	8.3	2.9	2.5	2.6	2.5	2.7	2.7	1.9	0.7	2.5	1.1	2.7
Alcohol usually taken with meals	3.1	4.9	9.0	-1.8	-2.0	-2.0	-2.1	-1.8	-1.9	-2.9	-3.0	-2.0	-2.4	-2.1
Forced expiratory volume in 1-second (FEV1)	3.1	10.4	15.5	2.2	3.8	3.7	3.7	3.9	3.7	2.8	1.0	3.6	3.4	2.4
Mother’s age at death	3.1	3.9	8.1	-1.2	-1.8	-1.8	-1.9	-1.6	-1.9	-2.8	-2.6	-2.0	-2.1	-1.3
Medication: Paracetamol	3.0	5.0	6.0	1.3	2.3	2.3	2.3	2.2	2.3	2.5	2.1	2.3	2.3	2.4
Medication for cholesterol, blood pressure or diabetes	3.0	5.0	10.4	-3.2	-2.4	-2.5	-2.4	-2.6	-2.4	-1.7	-0.1	-2.3	-1.1	-2.1
Commuting to job workplace: Walk	3.0	3.2	4.1	-1.5	-1.9	-1.9	-1.9	-1.9	-1.9	-1.5	-1.1	-1.9	-2.0	-2.0
Medication: Paracetamol	3.0	4.7	6.2	1.4	2.1	2.1	2.2	2.0	2.1	2.5	2.4	2.2	2.1	2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.9	3.4	7.1	2.7	1.8	1.9	1.8	2.0	1.9	1.6	1.2	1.8	1.2	2.0
Taking other prescription medications	2.8	4.3	7.6	2.8	2.3	2.3	2.2	2.5	2.2	1.4	0.4	2.1	0.9	2.4
Osteoporosis (self-reported)	2.8	3.5	5.2	0.4	2.1	2.0	2.1	2.0	2.0	1.7	1.2	2.0	2.3	2.0
Rheumatoid Arthritis	2.7	3.7	5.4	1.6	1.9	1.9	2.0	1.8	1.9	2.3	2.1	1.9	2.1	1.7
Pack years of smoking	2.7	3.9	6.5	1.2	1.9	1.8	1.9	1.7	1.8	2.3	2.6	1.9	2.1	2.3
Pack years adult smoking proportion	2.6	4.0	6.9	1.1	1.9	1.8	1.9	1.7	1.8	2.4	2.6	1.9	2.2	2.3
Chronic bronchitis/emphysema (mother)	2.5	3.0	3.8	-0.8	-1.8	-1.8	-1.8	-1.6	-1.9	-1.9	-1.5	-1.9	-2.0	-1.6
Medication: Atenolol	2.4	3.0	4.8	1.0	2.0	2.0	2.0	2.2	2.1	0.8	-0.3	2.0	1.3	1.9
Heart attack	2.3	3.0	3.9	1.4	1.8	1.8	1.8	1.9	2.0	1.6	0.8	1.9	1.8	1.9
Medication: Ramipril	2.3	3.0	4.9	2.2	1.9	2.0	1.9	2.2	2.0	1.2	0.4	1.9	1.0	1.4
Headache pain in last month	2.3	4.0	8.4	0.5	2.3	2.2	2.2	2.1	2.1	1.9	1.1	2.2	2.9	1.5
High cholesterol (Self-reported)	2.3	4.1	10.1	3.2	2.1	2.2	2.1	2.4	2.0	1.3	0.5	2.0	1.0	2.0
Lung FEV1/FVC ratio	2.2	11.3	16.9	-0.6	-3.9	-3.8	-3.8	-4.1	-4.1	-2.9	-1.1	-3.8	-3.7	-3.1
Family relationship satisfaction	2.2	2.7	3.7	1.9	1.7	1.8	1.7	1.9	1.7	1.9	1.2	1.6	0.9	1.3
Medication: Aspirin	2.2	2.8	4.4	1.1	1.9	1.9	1.9	1.9	1.9	1.4	1.0	1.9	1.2	2.1
Tinnitus: Yes, now most or all of the time	2.2	2.6	5.2	2.1	1.5	1.6	1.5	1.5	1.4	1.3	1.9	1.4	0.4	2.3
Average weekly beer plus cider intake	2.2	3.2	6.1	2.5	1.5	1.6	1.6	1.4	1.6	2.2	2.1	1.7	1.2	1.8
Vascular/heart problems diagnosed by doctor	2.2	5.9	9.7	-3.1	-2.6	-2.7	-2.6	-3.1	-2.9	-2.0	-0.1	-2.7	-1.2	-2.0
Waist circumference	2.1	7.8	12.2	3.5	3.1	3.2	3.0	3.5	2.9	2.5	1.5	2.8	1.9	2.0
Hair/balding pattern: Pattern 2	2.1	2.7	4.0	-0.5	-1.8	-1.8	-1.8	-1.7	-1.8	-1.8	-1.5	-1.8	-2.0	-1.2
Medication: Ventolin 100micrograms inhaler	2.1	2.7	3.2	1.0	1.7	1.6	1.7	1.6	1.6	1.7	1.8	1.7	1.8	1.8
Neck or shoulder pain in last month	2.1	3.0	11.3	1.9	1.1	1.1	1.2	0.9	1.0	2.5	3.4	1.2	1.8	1.2
Whole body fat mass	2.1	9.0	14.0	3.2	3.5	3.5	3.4	3.7	3.1	2.4	1.3	3.1	2.5	2.5
Heart attack/myocardial infarction (self-reported)	2.1	2.7	3.5	1.2	1.7	1.7	1.7	1.7	1.9	1.5	0.7	1.8	1.7	1.8
Heart disease (siblings)	2.1	2.6	4.1	1.1	1.6	1.6	1.7	1.6	1.7	1.6	1.4	1.7	1.4	2.0
Trunk fat mass	2.0	8.4	13.8	2.8	3.5	3.5	3.3	3.7	3.1	2.3	0.9	3.0	2.5	2.3
Medication: Simvastatin	2.0	2.9	6.8	2.6	1.9	1.9	1.8	2.1	1.7	1.2	0.2	1.7	0.9	1.6
Weight	2.0	10.0	16.2	3.3	3.7	3.7	3.5	4.0	3.3	2.6	1.3	3.3	2.6	2.3
Medication: Cholesterol lowering	2.0	3.1	8.9	3.0	1.9	1.9	1.8	2.1	1.9	1.0	-0.3	1.8	0.6	1.6
Prospective memory result	2.0	2.4	3.8	-1.6	-1.9	-1.9	-1.8	-2.0	-1.4	-0.9	-0.8	-1.6	-1.4	-1.4
Leg fat mass (right)	2.0	7.6	10.8	3.1	3.1	3.2	3.0	3.3	2.7	2.3	1.6	2.8	2.4	2.3
Arm fat percentage (right)	1.9	7.5	10.6	2.8	3.1	3.1	3.0	3.2	2.7	2.5	1.9	2.7	2.4	2.4
Arm fat mass (right)	1.9	7.8	12.2	3.2	3.2	3.2	3.1	3.5	2.9	2.4	1.4	2.8	2.3	2.1
Ever highly irritable/argumentative for 2 days	1.9	2.3	3.8	1.9	1.4	1.4	1.4	1.5	1.3	1.5	1.9	1.3	1.2	1.6
Hypothyroidism/myxoedema (self-reported)	1.9	3.7	5.2	1.2	2.3	2.2	2.2	2.3	2.1	1.3	0.1	2.1	2.1	2.0
Comparative height size at age 10	1.9	10.7	15.1	2.2	3.8	3.7	3.7	3.9	3.5	2.6	1.7	3.4	3.4	3.4
Had major operations	1.9	2.3	3.1	1.6	1.7	1.7	1.7	1.7	1.5	1.1	1.0	1.6	0.9	1.8
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.0	0.1	1.7	1.6	1.6	1.8	2.0	1.5	-0.6	1.8	1.5	0.8
Commuting to job workplace: Cycle	1.9	2.3	4.1	-1.1	-1.7	-1.8	-1.7	-2.0	-1.8	-1.1	-0.8	-1.6	-1.0	-1.5
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	3.5	-1.4	-1.6	-1.6	-1.6	-1.8	-1.9	-1.1	-0.3	-1.7	-1.1	-1.6
Osteoarthritis (self-reported)	1.8	2.4	4.9	2.0	1.4	1.5	1.5	1.5	1.4	1.2	1.6	1.4	0.4	2.2
Sensitivity / hurt feelings	1.7	3.0	5.4	-2.0	-1.7	-1.7	-1.7	-1.7	-1.9	-1.5	-1.4	-1.8	-1.2	-2.3
Leg fat percentage (right)	1.7	6.2	8.6	2.9	2.8	2.8	2.7	2.9	2.5	2.2	1.4	2.5	1.9	2.2
Leg fat mass (left)	1.7	6.5	9.2	2.9	2.9	2.9	2.8	3.0	2.5	2.2	1.6	2.5	2.1	2.1
Trunk fat percentage	1.6	6.4	10.2	2.4	3.0	3.0	2.9	3.2	2.7	2.0	0.8	2.6	2.1	2.2
Father’s age at death	1.6	2.1	2.5	-1.5	-1.5	-1.4	-1.5	-1.4	-1.5	-1.6	-1.3	-1.5	-1.4	-1.4
Body fat percentage	1.6	6.3	9.5	2.6	2.9	2.9	2.8	3.1	2.6	2.1	1.1	2.6	2.0	2.2
Arm fat percentage (left)	1.6	6.3	9.4	2.8	2.9	2.9	2.8	3.1	2.5	2.2	1.6	2.5	2.0	2.2
Height	1.5	28.8	45.0	2.1	6.5	6.3	6.2	6.7	6.3	4.1	-0.1	6.0	6.1	4.1
Hypothyroidism (self reported)	1.5	3.5	4.9	1.0	2.2	2.2	2.1	2.1	1.9	1.4	0.7	2.0	2.2	2.0
Shortness of breath walking on level ground	1.5	1.8	2.9	-0.8	-1.5	-1.5	-1.5	-1.6	-1.7	-1.2	-0.1	-1.6	-1.6	-0.8
Arm fat mass (left)	1.5	6.3	10.2	2.9	2.9	2.9	2.8	3.2	2.6	2.1	1.2	2.5	2.0	1.8
Mean Putamen Volume	1.4	1.6	2.8	-0.8	-1.3	-1.3	-1.3	-1.2	-1.4	-1.3	-0.8	-1.3	-1.7	-0.9
Leg fat-free mass (left)	1.4	7.3	12.2	2.3	3.2	3.2	3.0	3.5	2.9	2.3	1.0	2.8	2.8	1.5
Ever had bowel cancer screening	1.4	1.6	2.4	0.2	1.5	1.5	1.5	1.6	1.5	0.8	0.1	1.4	1.4	1.3
Ever taken oral contraceptive pill	1.4	1.5	2.7	-0.2	-1.5	-1.5	-1.4	-1.6	-1.4	-0.4	0.7	-1.4	-1.6	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.4	-2.1	-1.0	-1.1	-1.1	-1.1	-1.4	-1.2	-1.2	-1.4	0.0	-1.7
Body mass index (BMI)	1.3	5.4	11.1	3.3	2.5	2.5	2.4	2.7	2.2	2.1	1.8	2.2	1.6	1.8
Leg predicted mass (left)	1.3	6.8	11.4	2.3	3.1	3.1	3.0	3.4	2.8	2.3	1.0	2.7	2.7	1.4
Medication: Blood pressure	1.3	2.3	4.9	2.2	1.6	1.7	1.6	1.9	1.7	0.8	-0.8	1.6	0.5	1.3
Medication: Aspirin	1.3	1.7	3.0	1.2	1.5	1.5	1.5	1.6	1.6	0.8	0.3	1.5	0.5	1.7
Guilty feelings	1.3	2.0	4.5	-2.0	-1.1	-1.1	-1.1	-1.1	-1.1	-1.2	-2.1	-1.1	-0.7	-2.0
Financial situation satisfaction	1.3	1.6	2.8	-1.4	-1.4	-1.5	-1.4	-1.5	-1.7	-0.5	0.3	-1.6	-0.6	-1.1
Basal metabolic rate	1.3	7.1	11.7	2.6	3.1	3.1	3.0	3.4	2.8	2.4	1.1	2.8	2.6	1.4
Body Mass Index (BMI) (2010)	1.2	1.6	2.1	0.2	1.5	1.4	1.5	1.4	1.4	1.4	0.7	1.5	1.5	0.8
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	4.1	0.6	1.3	1.2	1.3	1.1	1.1	1.2	0.8	1.3	2.0	0.6
Illnesses of siblings: Diabetes	1.2	1.4	2.3	-0.9	-1.4	-1.4	-1.3	-1.3	-1.3	-0.9	-0.6	-1.3	-0.9	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	3.5	1.2	1.8	1.7	1.7	1.9	1.7	1.5	1.1	1.6	1.4	1.4
Leg fat percentage (left)	1.2	4.4	6.7	2.6	2.3	2.3	2.3	2.4	2.0	1.9	1.3	2.1	1.6	1.8
High blood pressure (mother)	1.1	1.6	2.0	-1.3	-1.4	-1.4	-1.3	-1.4	-1.1	-1.1	-1.3	-1.2	-1.1	-1.3
Financial difficulties in last 2 years	1.1	1.5	2.6	-0.8	-1.1	-1.0	-1.1	-0.9	-1.1	-1.5	-1.5	-1.2	-1.2	-1.6
Diastolic blood pressure, automated reading	1.1	3.4	4.4	1.4	2.1	2.1	2.0	2.1	1.9	1.8	1.3	1.9	1.9	1.7
Cardiovascular Disease	1.0	3.2	5.6	2.4	2.0	2.1	1.9	2.3	2.0	1.5	0.1	1.9	1.1	1.2
Diabetes (mother)	1.0	1.2	2.3	-0.4	-1.1	-1.1	-1.2	-1.1	-1.2	-1.5	-1.1	-1.2	-1.0	-1.0
Townsend deprivation index at recruitment	1.0	1.4	3.2	1.0	1.0	1.0	1.0	0.9	1.1	1.8	1.7	1.1	0.8	1.2
Medication: Levothyroxine sodium	1.0	1.7	2.4	1.1	1.5	1.5	1.5	1.5	1.3	0.8	0.2	1.3	1.4	1.5
Trunk fat-free mass	1.0	5.8	9.3	2.3	2.8	2.8	2.6	3.0	2.6	2.2	1.0	2.5	2.5	1.2
Trunk predicted mass	1.0	5.5	8.9	2.3	2.7	2.7	2.6	3.0	2.5	2.2	1.0	2.5	2.4	1.1
Medication for pain relief, constipation, heartburn	1.0	1.7	3.6	-0.7	-1.4	-1.3	-1.4	-1.3	-1.3	-1.1	-1.0	-1.3	-1.2	-1.9
Knee pain experienced in last month	1.0	1.5	2.3	1.1	1.3	1.3	1.2	1.2	1.0	1.2	1.5	1.1	1.0	1.5
Whole body fat-free mass	1.0	5.5	9.0	2.2	2.7	2.7	2.6	3.0	2.5	2.2	1.0	2.4	2.5	1.1
Leg fat-free mass (right)	1.0	5.4	9.2	2.0	2.8	2.8	2.6	3.0	2.5	2.1	0.9	2.4	2.4	1.0
Whole body water mass	1.0	5.5	9.1	2.3	2.7	2.7	2.6	3.0	2.5	2.2	1.0	2.4	2.4	1.1
Leg predicted mass (right)	1.0	5.2	9.0	2.0	2.7	2.7	2.6	3.0	2.4	2.0	0.8	2.4	2.4	1.0
Reaction Time	0.9	1.8	5.4	-2.3	-1.3	-1.4	-1.3	-1.6	-1.4	-0.4	0.1	-1.3	0.1	-1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	1.9	1.4	1.1	1.2	1.1	1.3	1.1	0.9	0.9	1.0	0.3	1.4
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.6	1.0	1.0	1.0	1.0	0.9	0.6	0.8	1.3	0.8	1.0	1.2
Vitamin and mineral supplements	0.9	1.2	5.5	-0.6	-0.7	-0.7	-0.7	-0.6	-0.6	-1.0	-2.3	-0.6	-0.7	-1.7
Had menopause	0.9	1.1	1.8	-0.5	-1.0	-1.0	-1.0	-0.8	-0.9	-1.3	-1.3	-1.0	-1.3	-1.2
Illnesses of siblings	0.9	1.3	1.9	-0.6	-1.3	-1.2	-1.3	-1.2	-1.3	-1.0	-0.4	-1.3	-0.9	-1.4
Alcohol intake versus 10 years previously	0.9	1.4	2.3	-0.5	-1.4	-1.4	-1.4	-1.4	-1.5	-0.7	0.0	-1.5	-1.1	-0.9
Peak expiratory flow (PEF)	0.9	2.1	3.7	1.7	1.6	1.7	1.6	1.9	1.7	1.1	-0.0	1.6	1.1	0.7
Qualifications: nursing, teaching	0.9	1.5	3.8	-1.2	-1.2	-1.1	-1.2	-1.0	-0.9	-0.9	-1.4	-1.0	-1.2	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.8	-1.7	-1.0	-1.0	-1.0	-1.0	-1.1	-1.0	-0.7	-1.1	-0.8	-0.8
Eye problems/disorders: Glaucoma	0.9	1.0	1.4	-0.7	-0.9	-0.9	-1.0	-1.0	-1.1	-1.1	-1.2	-1.1	-0.8	-1.2
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.6	-0.5	-1.1	-1.1	-1.1	-1.0	-0.9	-1.1	-1.3	-1.0	-1.6	-1.0
Ever depressed for a whole week	0.9	1.1	2.1	1.0	1.0	1.0	1.0	1.0	0.9	1.4	1.4	0.9	0.8	0.7
Basal cell carcinoma (self-reported)	0.9	1.1	1.4	1.0	1.2	1.2	1.2	1.1	1.1	0.8	0.3	1.1	0.9	1.2
Medication for hormone replacement therapy	0.8	0.9	2.0	1.4	0.8	0.9	0.8	0.9	0.8	0.8	1.1	0.8	0.8	1.0
Severe depression (siblings)	0.8	0.9	2.5	0.5	1.1	1.1	1.0	1.3	1.1	0.2	-1.6	1.0	0.3	-0.1
Serious illness, injury or assault to yourself	0.8	1.0	2.2	0.9	-1.0	-0.9	-1.0	-1.0	-1.3	-0.3	1.5	-1.1	-1.0	-0.3
Pain all over the body in last month	0.8	0.9	1.3	0.5	1.1	1.1	1.1	1.1	0.9	0.6	0.2	0.9	1.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	5.1	-2.2	-0.5	-0.6	-0.6	-0.5	-0.8	-0.9	-1.7	-0.7	0.2	-1.9
Pulse wave Arterial Stiffness index	0.8	0.9	1.5	0.6	1.2	1.2	1.2	1.2	1.2	0.7	-0.4	1.2	0.7	0.4
Pulse wave peak to peak time	0.8	0.9	1.4	-0.7	-1.2	-1.2	-1.1	-1.2	-1.2	-0.7	0.3	-1.2	-0.6	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	4.5	-0.7	-0.8	-0.8	-0.8	-0.8	-1.1	-0.1	-0.2	-0.9	-0.2	-2.1
Miserableness	0.8	1.3	3.8	-0.5	1.3	1.2	1.2	1.2	1.1	1.3	-0.1	1.2	2.0	-0.1
Medication: Atorvastatin	0.8	1.0	3.0	1.7	0.9	1.0	0.9	1.1	1.0	1.0	0.2	0.9	0.3	0.7
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.2	0.5	1.6	1.6	1.5	1.6	1.3	0.8	0.2	1.4	1.8	0.9
BMI	0.7	4.1	7.0	2.6	2.1	2.2	2.1	2.3	1.9	2.1	1.8	1.9	1.6	1.1
High blood pressure	0.7	1.9	5.0	2.2	1.4	1.5	1.4	1.8	1.6	1.0	-0.5	1.4	0.3	1.0
Number of incorrect matches in round	0.7	1.1	2.0	1.4	1.1	1.1	1.1	1.2	1.2	1.2	0.4	1.1	0.5	0.8
Noisy workplace	0.7	0.8	1.3	1.0	1.0	0.9	1.0	0.8	0.6	0.9	0.9	0.8	1.1	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	3.0	0.0	1.1	1.0	1.1	0.9	0.9	1.1	1.1	1.0	1.7	1.2
Standing height	0.7	6.9	12.8	0.7	3.2	3.1	3.0	3.6	3.3	1.7	-0.7	3.0	2.9	1.7
Number of full sisters	0.7	0.8	4.5	-1.3	-0.3	-0.3	-0.3	-0.3	0.3	-0.2	-2.1	0.1	-0.3	-1.5
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.6	0.6	1.0	1.0	1.0	1.2	1.3	0.9	-0.0	1.0	0.5	0.7
Back pain experienced in last month	0.7	1.0	2.1	0.5	0.9	1.0	1.0	1.0	1.5	1.1	0.5	1.3	0.6	0.9
Arm fat-free mass (left)	0.7	3.6	6.0	1.9	2.2	2.2	2.1	2.5	2.1	1.8	0.6	2.0	1.9	0.6
Arm predicted mass (left)	0.7	3.4	5.4	2.1	2.1	2.1	2.0	2.3	1.9	1.8	0.8	1.9	1.8	0.7
HbA1C	0.6	0.7	4.2	0.1	-0.5	-0.4	-0.3	-0.2	-0.4	-1.4	-0.5	-0.9	-2.1	-0.2
Chronotype (morning person)	0.6	1.3	2.1	-1.1	-1.3	-1.4	-1.3	-1.5	-1.4	-1.0	-0.4	-1.3	-0.7	-0.7
Hand grip strength (left)	0.6	1.6	3.0	-1.2	-1.3	-1.3	-1.3	-1.3	-1.4	-1.1	-0.9	-1.4	-0.5	-1.7
Maternal smoking around birth	0.6	0.9	6.3	0.9	-0.6	-0.5	-0.5	-0.7	-0.7	0.4	2.5	-0.6	-0.5	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	3.5	0.7	1.2	1.1	1.1	1.0	0.7	1.3	1.7	1.0	1.9	0.9
Qualifications: CSEs or equivalent	0.6	0.8	1.3	0.1	-1.0	-1.0	-1.0	-1.0	-1.1	-0.6	-0.6	-1.0	-0.8	-1.1
Chronic bronchitis/emphysema (father)	0.6	0.7	1.5	-0.4	0.9	0.9	0.9	1.1	1.1	0.2	-1.2	1.0	0.6	-0.2
Mouth/teeth dental problems	0.6	0.9	3.1	0.7	-0.9	-0.7	-0.8	-0.6	-0.7	-1.0	-0.8	-0.8	-1.8	-1.0
Hair/balding pattern: Pattern 4	0.6	1.5	4.0	-1.3	-1.3	-1.3	-1.2	-1.5	-1.3	-0.5	-0.3	-1.2	-0.6	-2.0
Pulse wave reflection index	0.6	0.8	1.5	0.6	1.1	1.1	1.1	1.2	1.2	0.6	-0.5	1.1	0.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.4	1.2	1.2	1.2	1.1	1.1	0.8	0.6	0.7	0.9	1.1	0.7
Health satisfaction	0.6	0.8	1.3	-1.1	-0.8	-0.9	-0.9	-0.9	-1.2	-0.7	-0.5	-1.1	-0.7	-1.1
Age at last live birth	0.6	0.9	2.1	-1.1	-0.8	-0.8	-0.8	-0.6	-0.5	-1.2	-1.4	-0.7	-0.8	-0.9
Lupus	0.5	0.7	1.6	0.5	-1.0	-0.9	-1.0	-0.9	-0.6	-1.0	-0.8	-0.8	-1.2	-0.3
Neuroticism (2016)	0.5	0.7	1.2	-0.2	0.9	0.9	0.9	0.9	1.0	0.9	-0.2	1.0	1.1	0.4
Triglycerides	0.5	0.8	1.1	-0.6	-0.9	-0.9	-0.9	-0.9	-1.0	-0.9	-0.6	-1.0	-0.8	-1.0
Neuroticism	0.5	1.2	4.6	-1.7	-0.5	-0.6	-0.6	-0.5	-0.7	-1.0	-2.1	-0.7	-0.1	-1.7
Impedance of leg (left)	0.5	2.6	4.5	-2.1	-1.8	-1.8	-1.7	-2.0	-1.6	-1.5	-1.0	-1.6	-1.4	-0.7
Past tobacco smoking	0.5	0.9	1.4	-1.1	-1.2	-1.2	-1.1	-1.2	-1.0	-0.4	0.6	-1.0	-0.3	-0.6
Happiness	0.5	0.6	1.3	1.1	0.9	0.9	0.8	1.1	0.8	0.6	0.1	0.7	-0.1	0.6
Birth weight of first child	0.5	0.9	2.5	-0.3	1.1	1.0	1.0	1.0	0.7	0.7	1.0	0.8	1.6	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.6	-1.2	-0.8	-0.8	-0.8	-0.8	-0.7	-0.3	-0.6	-0.7	-0.4	-1.1
High blood pressure (siblings)	0.5	0.8	1.5	0.2	1.0	1.0	1.0	1.1	1.2	0.5	-0.6	1.1	0.6	0.8
Number of full brothers	0.5	0.6	1.1	0.3	0.7	0.7	0.8	0.5	0.8	1.0	0.9	0.9	1.0	0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.4	-0.7	-1.0	-1.0	-0.9	-1.2	-1.0	-0.4	0.2	-0.9	-0.6	-0.1
Medication: Seretide 50 evohaler	0.5	0.6	1.1	-0.9	-0.8	-0.9	-0.8	-1.1	-0.9	-0.6	0.2	-0.8	-0.2	-0.4
Mean time to correctly identify matches	0.5	0.9	2.0	-1.4	-1.0	-1.1	-1.0	-1.2	-1.1	-0.5	-0.5	-1.0	-0.3	-0.6
Arm predicted mass (right)	0.5	2.3	4.1	2.0	1.7	1.8	1.6	2.0	1.6	1.4	0.5	1.6	1.2	0.3
Hypertension (Self-reported)	0.5	1.5	3.7	1.9	1.3	1.3	1.2	1.6	1.4	0.9	-0.5	1.2	0.3	0.7
Eye problems/disorders: Cataract	0.5	0.6	1.2	0.0	0.8	0.8	0.8	0.7	0.7	0.8	0.8	0.8	0.8	1.1
Medication for cholesterol	0.5	0.8	2.3	-1.5	-0.9	-0.9	-0.9	-1.0	-0.9	-0.7	-0.6	-0.8	-0.1	-0.9
Mineral and other dietary supplements	0.5	0.7	1.1	-1.0	-0.9	-0.9	-0.9	-1.0	-1.0	-0.6	0.2	-0.9	-0.1	-0.9
Commuting to job workplace: Public transport	0.5	0.6	2.0	-1.4	-0.6	-0.7	-0.7	-0.7	-0.7	-1.0	-0.4	-0.7	-0.4	-0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.3	-1.1	-0.8	-0.9	-0.8	-0.9	-1.0	-0.9	-0.0	-0.9	-0.7	-0.1
Depressed Affect (Nagel 2018)	0.4	0.9	1.8	-0.5	1.2	1.1	1.1	1.2	0.9	0.6	-0.4	0.9	1.3	0.1
Depression (Nagel 2018)	0.4	0.6	2.5	-1.3	-0.1	-0.2	-0.3	0.0	-0.4	-1.1	-1.6	-0.5	-0.1	-0.7
Age at First Birth	0.4	0.6	1.3	0.1	-1.0	-0.9	-0.9	-0.9	-0.9	-0.6	-0.3	-0.8	-1.1	-0.8
Coronary Artery Disease (CAD)	0.4	0.5	1.3	-0.0	0.5	0.5	0.6	0.7	1.1	0.9	-0.5	1.1	0.6	0.2
LDL Cholesterol	0.4	0.6	1.3	-1.0	-0.7	-0.8	-0.7	-1.0	-1.1	-0.8	0.2	-0.9	0.2	-0.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.3	0.8	-0.6	-0.5	-0.6	-0.3	-0.1	-0.4	-0.4	-0.1	-1.5	-0.9
Systolic Blood Pressure	0.4	1.8	2.5	0.9	1.5	1.5	1.5	1.5	1.6	1.5	0.6	1.5	1.2	0.9
Ever had hysterectomy (womb removed)	0.4	0.5	0.7	0.2	0.8	0.8	0.8	0.8	0.8	0.5	0.4	0.8	0.7	0.5
Diabetes (father)	0.4	0.5	0.9	-0.8	0.7	0.7	0.7	0.8	0.9	0.6	-0.3	0.8	1.0	-0.2
Age when periods started (menarche)	0.4	0.9	4.5	-2.1	-0.6	-0.7	-0.6	-0.7	-0.7	-1.0	-1.1	-0.7	0.2	-0.7
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.6	1.6	0.8	0.9	0.8	1.1	1.1	0.9	0.0	1.0	0.2	0.4
Multivitamins +/- minerals	0.4	0.6	0.8	-0.9	-0.8	-0.8	-0.8	-0.8	-0.8	-0.6	0.6	-0.9	-0.8	0.2
Supplements: Glucosamine	0.4	0.6	2.7	1.6	0.6	0.7	0.6	0.7	0.5	0.1	0.2	0.5	-0.4	1.0
Had other major operations	0.4	0.5	2.5	0.9	0.3	0.4	0.3	0.4	0.1	0.1	1.6	0.2	-0.4	1.0
Lung cancer (father)	0.4	0.4	1.8	0.5	-0.4	-0.3	-0.4	-0.1	0.1	-0.6	-1.3	-0.1	-1.4	-0.2
Length of working week for main job	0.4	0.4	2.0	-0.9	-0.4	-0.5	-0.4	-0.3	-0.1	-0.1	-1.0	-0.3	0.2	-1.4
Loud music exposure frequency	0.4	0.5	1.7	0.6	0.5	0.5	0.5	0.4	0.3	0.3	1.3	0.4	0.4	1.2
Birth weight	0.4	0.9	1.3	0.3	1.1	1.0	1.1	1.0	1.1	0.9	0.4	1.1	0.8	1.1
Arm fat-free mass (right)	0.4	2.1	3.6	1.9	1.6	1.6	1.5	1.9	1.5	1.3	0.6	1.4	1.2	0.4
Pulse rate, automated reading	0.4	1.2	2.9	1.4	1.0	1.0	1.0	1.0	0.5	1.0	1.7	0.7	0.9	1.3
Chest pain or discomfort	0.4	0.5	0.9	0.0	0.9	0.9	0.9	1.0	0.8	0.5	-0.3	0.8	0.9	0.4
Alcohol drinker status: Previous	0.4	0.4	2.5	-0.5	-0.3	-0.4	-0.3	-0.5	-0.5	0.7	1.6	-0.4	0.3	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.5	0.9	1.1	1.1	1.1	1.2	1.0	0.4	0.2	1.0	1.2	0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	3.4	-1.8	0.2	0.1	0.2	0.2	0.1	-0.3	-0.6	0.1	0.9	0.1
Alzheimer’s Disease (in father)	0.3	0.4	1.7	1.3	-0.5	-0.5	-0.5	-0.5	-0.6	0.0	0.3	-0.6	-0.5	-0.5
Crohns Disease (2017)	0.3	0.7	1.8	-0.4	-0.8	-0.8	-0.9	-0.6	-0.5	-1.0	-0.9	-0.9	-1.4	-0.5
Ovarian Cancer	0.3	0.4	2.4	1.5	0.2	0.3	0.2	0.5	0.6	0.6	0.5	0.3	-0.8	0.1
Prostate Cancer	0.3	0.4	2.2	0.7	-0.5	-0.4	-0.4	-0.4	-0.5	-0.6	0.4	-0.5	-1.5	-0.1
Allergy or Eczema	0.3	0.8	1.7	1.3	0.8	0.9	0.8	1.1	1.3	0.7	-0.9	1.1	0.2	-0.0
Average weekly spirits intake	0.3	0.4	1.6	0.9	0.4	0.4	0.4	0.3	0.1	0.5	1.3	0.2	0.4	0.7
Medication: Co-codamol	0.3	0.3	0.8	-0.6	-0.6	-0.6	-0.6	-0.4	-0.1	-0.4	-0.9	-0.4	-0.8	-0.6
Impedance of leg (right)	0.3	1.5	3.5	-1.9	-1.2	-1.3	-1.2	-1.4	-1.1	-1.3	-1.1	-1.1	-0.9	-0.3
Fed-up feelings	0.3	0.6	2.7	-1.3	0.6	0.5	0.6	0.4	0.2	0.6	-0.0	0.4	1.6	-0.2
Sitting height	0.3	1.9	3.8	0.1	1.6	1.5	1.4	2.0	1.6	0.1	-1.9	1.4	1.3	-0.3
Nervous feelings	0.3	0.5	1.6	-0.5	0.7	0.7	0.6	0.8	0.8	-0.0	-1.3	0.7	0.4	0.1
Hearing difficulty/problems with background noise	0.3	0.4	3.3	1.8	0.3	0.4	0.3	0.3	0.1	0.1	0.6	0.2	-0.4	0.5
Diabetes (self-reported)	0.3	0.5	1.3	-0.0	-0.7	-0.7	-0.7	-0.7	-0.8	-0.3	-0.4	-0.7	-0.9	-1.1
Time employed in main current job	0.3	0.3	0.6	-0.4	-0.5	-0.5	-0.5	-0.5	-0.5	-0.8	-0.7	-0.5	-0.7	0.0
Worrier / anxious feelings	0.3	0.7	1.7	-0.9	-0.7	-0.7	-0.7	-0.6	-0.7	-0.8	-1.3	-0.8	-0.6	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.5	1.2	0.4	0.4	0.4	0.3	0.2	0.3	0.7	0.4	0.2	0.9
Wheeze or whistling in the chest in last year	0.3	0.5	2.2	1.5	0.7	0.7	0.6	0.9	0.6	0.5	0.5	0.6	0.0	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.2	0.9	0.4	0.5	0.5	0.5	0.6	1.1	0.7	0.5	0.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.2	1.5	-0.1	0.0	0.0	-0.1	0.1	0.3	0.9	0.1	-0.6	0.7
Alcohol intake frequency.	0.3	0.7	1.3	0.2	-0.9	-0.9	-1.0	-0.8	-1.2	-0.7	0.2	-1.1	-0.8	-1.0
Overall health rating	0.3	0.6	1.7	1.0	0.6	0.6	0.6	0.6	0.6	1.1	1.3	0.5	0.4	0.8
Supplements: Vitamin C	0.3	0.3	2.4	0.3	0.0	0.0	0.1	-0.1	-0.0	0.7	1.5	0.1	0.4	0.4
Average weekly red wine intake	0.3	0.4	1.4	0.7	0.6	0.6	0.5	0.6	0.1	-0.1	1.2	0.3	0.1	1.2
Mood swings	0.3	0.5	3.0	-1.7	-0.2	-0.3	-0.3	-0.3	-0.3	-0.2	-0.9	-0.3	0.2	-0.8
Loneliness, isolation	0.3	0.4	0.9	-0.4	0.6	0.6	0.6	0.7	0.6	0.9	-0.2	0.6	0.7	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	0.3	0.7	0.8	0.7	0.9	0.9	0.5	0.4	0.8	0.5	0.8
Hearing aid user	0.3	0.3	0.7	0.5	0.5	0.6	0.5	0.7	0.8	-0.2	-0.8	0.7	-0.0	0.5
Illnesses of father: High blood pressure	0.3	0.4	0.9	0.3	-0.5	-0.4	-0.5	-0.3	-0.4	-0.8	-0.9	-0.5	-0.9	-0.9
Cholesterol lowering medication	0.3	0.5	2.3	1.5	0.6	0.7	0.6	0.9	0.7	0.2	-0.2	0.6	-0.4	0.5
Impedance of whole body	0.3	1.4	5.7	-2.4	-0.9	-1.0	-0.9	-1.1	-0.8	-1.3	-1.4	-0.9	-0.6	-0.4
Bipolar Disorder (2018)	0.2	0.4	1.6	1.3	0.4	0.5	0.4	0.5	0.3	0.8	0.6	0.4	-0.5	0.4
Neuroticism (Nagel 2018)	0.2	0.4	1.8	-1.1	0.2	0.1	0.1	0.3	0.0	-0.2	-1.4	-0.0	0.2	-1.1
Worry (Nagel 2018)	0.2	0.3	1.7	-0.9	-0.1	-0.2	-0.2	-0.0	-0.2	-0.7	-1.3	-0.3	-0.3	-0.5
Bipolar Disorder (2011)	0.2	0.2	1.0	0.0	-0.4	-0.3	-0.3	-0.3	-0.2	0.1	-0.3	-0.2	-1.0	-0.6
Crohns Disease (2012)	0.2	0.3	1.3	-0.6	-0.2	-0.2	-0.2	-0.1	0.0	-0.5	-1.1	-0.1	-0.8	-0.5
Waist Hip Ratio (WHR)	0.2	0.8	1.4	-0.5	-1.1	-1.1	-1.1	-1.0	-0.8	-0.5	-0.1	-0.9	-1.1	-1.2
Relative age of first facial hair	0.2	0.3	1.0	0.2	0.7	0.7	0.6	1.0	0.8	0.2	-0.0	0.6	0.2	0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.8	0.6	0.2	0.2	0.2	0.5	0.6	0.1	-0.9	0.3	-0.5	0.1
Current tobacco smoking	0.2	0.3	1.0	-1.0	-0.2	-0.3	-0.2	-0.3	-0.2	0.6	0.8	-0.3	0.7	-0.6
Relative age voice broke	0.2	0.3	1.7	-1.3	-0.4	-0.5	-0.4	-0.5	-0.4	-0.2	0.0	-0.4	0.1	-0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.4	1.2	0.3	0.3	0.3	0.3	0.0	-0.1	0.4	0.1	-0.2	1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	0.2	-0.1	-0.1	-0.1	0.0	0.2	-0.7	-1.1	0.0	-0.6	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.4	-1.6	-0.1	-0.2	-0.2	-0.3	-0.4	-0.1	-0.5	-0.3	0.6	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.9	0.1	0.4	0.4	0.4	0.3	0.2	0.8	1.3	0.3	1.4	0.2
Neuroticism score	0.2	0.5	1.9	-1.4	0.3	0.2	0.3	0.3	0.3	0.4	-1.1	0.3	1.0	-0.9
Impedance of arm (right)	0.2	0.8	2.9	-1.7	0.8	0.7	0.7	0.7	0.8	0.1	-0.7	0.7	1.1	0.7
Hair/balding pattern: Pattern 3	0.2	0.3	2.2	-1.5	-0.1	-0.1	-0.0	-0.2	0.2	0.1	-0.6	0.2	0.3	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.9	0.9	0.6	0.6	0.5	0.8	0.5	-0.1	-0.7	0.4	-0.4	0.3
Blood clot in the leg (DVT)	0.2	0.2	0.4	0.4	0.4	0.4	0.4	0.4	0.3	0.7	0.6	0.3	0.4	0.5
Glaucoma (self-reported)	0.2	0.2	0.4	0.2	-0.5	-0.5	-0.5	-0.6	-0.6	-0.5	-0.1	-0.6	-0.6	-0.1
Gout (self-reported)	0.2	0.3	0.9	0.3	-0.5	-0.4	-0.4	-0.4	-0.2	-0.8	-0.9	-0.3	-0.8	-0.3
Medication: Amlodipine	0.2	0.3	1.2	1.0	0.1	0.1	0.1	0.4	0.4	-0.2	-1.1	0.2	-0.8	0.2
Worry too long after embarrassment	0.2	0.4	2.8	-1.7	0.2	0.1	0.2	0.0	0.3	0.1	-0.7	0.3	0.8	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.9	0.9	0.2	0.3	0.2	0.6	0.4	-0.3	-0.8	0.2	-0.9	0.1
Number of children fathered	0.2	0.2	0.8	0.2	-0.3	-0.3	-0.3	-0.2	-0.2	-0.3	-0.9	-0.2	-0.5	-0.6
Age at first live birth	0.2	0.3	0.7	-0.8	-0.6	-0.6	-0.6	-0.5	-0.5	-0.6	-0.3	-0.6	-0.4	-0.6
Migraine (self-reported)	0.2	0.2	0.7	0.1	0.4	0.3	0.4	0.1	0.2	0.3	0.7	0.3	0.8	0.8
Medication: Ibuprofen	0.2	0.2	1.5	-0.4	0.1	0.1	0.1	-0.0	-0.1	0.3	1.2	0.0	0.4	0.6
Medication: Allopurinol	0.2	0.3	0.9	0.3	0.5	0.6	0.6	0.6	0.8	-0.2	-0.9	0.7	0.2	0.5
Smoking status: Previous	0.2	0.3	1.4	0.4	0.6	0.6	0.6	0.7	0.5	-0.2	-1.2	0.5	-0.2	0.1
Long-standing illness, disability or infirmity	0.2	0.4	1.5	1.2	0.5	0.5	0.5	0.6	0.5	0.5	0.6	0.4	-0.0	0.8
Diabetes diagnosed by doctor	0.2	0.4	1.0	0.8	-0.6	-0.5	-0.6	-0.6	-0.7	-0.4	-0.2	-0.6	-1.0	-0.6
Asthma (self-reported)	0.2	0.4	1.8	1.3	0.5	0.5	0.4	0.6	0.6	0.8	0.5	0.5	0.7	0.2
Medication: Gliclazide	0.2	0.2	1.0	0.7	-0.2	-0.2	-0.2	-0.4	-0.5	0.0	1.0	-0.3	-0.1	0.1
Wears glasses or contact lenses	0.2	0.2	0.5	0.4	0.3	0.4	0.4	0.3	0.4	0.7	0.7	0.4	-0.2	0.3
Medication: Bendroflumethiazide	0.2	0.3	1.1	0.3	-0.5	-0.4	-0.5	-0.3	-0.3	-0.4	-1.1	-0.4	-0.5	-0.8
Medication: Lisinopril	0.2	0.2	0.7	-0.8	0.4	0.4	0.3	0.3	0.3	0.3	-0.6	0.4	0.7	-0.5
Alcohol drinker status: Never	0.2	0.2	1.2	0.7	-0.1	-0.1	-0.1	-0.1	-0.5	-0.3	1.1	-0.3	-0.3	0.5
Ever smoked	0.2	0.4	1.3	-0.1	0.8	0.8	0.7	0.8	0.6	-0.1	-1.2	0.6	0.2	-0.0
Bipolar Disorder or Schizophrenia	0.1	0.1	0.8	0.7	0.1	0.1	0.1	0.1	-0.1	0.4	0.9	-0.1	-0.2	0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.5	-0.3	-0.1	-0.5	0.1
Alzheimer’s Disease (including proxy)	0.1	0.2	1.4	1.2	-0.1	-0.1	-0.1	-0.1	-0.2	-0.0	0.4	-0.1	-0.6	0.2
Irritable Bowel Disease (IBD)	0.1	0.1	0.8	0.1	-0.2	-0.2	-0.3	0.1	0.1	-0.4	-0.3	-0.3	-0.9	-0.0
Major Depression (MDD)	0.1	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0
Breast Cancer	0.1	0.3	1.2	1.1	0.3	0.4	0.3	0.5	0.4	0.5	0.7	0.3	-0.3	0.4
Fasting Glucose	0.1	0.1	0.6	0.1	0.2	0.1	0.1	0.1	0.4	0.5	-0.3	0.4	0.8	-0.4
Primary Biliary Cirrhosis	0.1	0.1	0.7	0.2	0.0	0.0	-0.0	0.1	-0.3	-0.0	0.9	-0.2	0.4	0.0
Ulcerative Colitis	0.1	0.1	0.3	0.5	0.1	0.1	0.1	0.2	0.1	0.3	0.6	0.0	-0.5	0.3
Blood Eosinophil Count	0.1	0.5	3.2	-0.7	-0.2	-0.3	-0.3	-0.2	-0.3	-0.0	-1.8	-0.3	0.1	-1.1
Blood Platelet Count	0.1	0.8	4.4	-0.8	-0.2	-0.1	-0.2	0.2	0.1	-0.2	-2.1	-0.2	-1.2	-1.5
Blood White Count	0.1	0.7	1.2	0.5	-0.8	-0.8	-0.8	-0.7	-0.8	-0.6	-0.7	-0.8	-1.0	-1.1
Respiratory disease	0.1	0.3	2.3	1.5	-0.2	-0.2	-0.2	-0.0	-0.1	0.1	0.5	-0.2	-0.2	0.4
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.3	-0.3	0.3	0.3	0.3	0.3	-0.1	0.2	0.4	0.0	0.5	0.2
Hearing difficulty/problems: Yes	0.1	0.2	1.0	0.8	-0.1	0.0	-0.1	0.1	0.1	-0.3	-0.4	-0.0	-1.0	-0.0
Systolic blood pressure, automated reading	0.1	0.3	0.6	0.5	0.5	0.6	0.5	0.6	0.8	0.6	-0.2	0.7	0.3	0.2
Supplements: Zinc	0.1	0.1	0.2	0.4	-0.2	-0.1	-0.2	-0.2	-0.2	-0.2	0.2	-0.2	-0.4	-0.1
Medication: Metformin	0.1	0.2	0.8	0.8	-0.3	-0.2	-0.3	-0.2	-0.2	0.2	-0.4	-0.2	-0.5	-0.9
Hand grip strength (right)	0.1	0.3	0.8	-0.6	-0.5	-0.5	-0.5	-0.4	-0.5	-0.4	-0.4	-0.5	0.0	-0.9
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.1	-0.3	-0.4	-0.4	-0.4	-0.5	-0.5	0.2	-0.4	-0.1	-0.0
Qualifications: None of the above	0.1	0.3	1.2	-0.4	0.2	0.1	0.3	-0.0	0.3	0.8	1.1	0.3	0.6	0.9
Allergy	0.1	0.1	0.9	-0.9	0.2	0.2	0.2	-0.0	-0.1	-0.3	0.2	0.1	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.6	0.1	0.1	0.1	0.1	0.2	0.3	0.1	-0.8	0.2	0.2	-0.6
Fluid intelligence score	0.1	0.2	1.0	-1.0	-0.1	-0.2	-0.2	-0.2	-0.3	-0.5	-0.6	-0.3	0.3	-0.7
Falls in the last year	0.1	0.1	0.4	0.2	0.3	0.3	0.3	0.1	0.3	0.6	0.6	0.4	0.3	0.4
Number of live births	0.1	0.1	0.8	0.9	0.1	0.1	0.1	0.2	0.2	0.0	0.0	0.2	-0.3	0.1
Pulse rate	0.1	0.1	0.8	0.2	0.2	0.2	0.1	0.2	-0.1	0.5	0.9	-0.0	0.5	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.1	0.3	-0.1	-0.0	-0.1	0.2	-0.1	-0.6	-1.0	-0.2	-0.8	-0.4
Asthma	0.1	0.2	0.8	0.9	0.2	0.2	0.2	0.4	0.4	0.5	0.1	0.2	0.5	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	-0.5	0.0	-0.0	0.0	-0.1	-0.2	0.2	0.6	-0.1	0.4	0.3
Depression (self-reported)	0.1	0.2	0.8	0.9	0.4	0.4	0.3	0.6	0.1	-0.0	0.2	0.1	-0.4	0.1
Illnesses of mother	0.1	0.2	0.6	0.8	0.2	0.3	0.3	0.3	0.2	0.5	0.7	0.3	0.3	0.0
Impedance of arm (left)	0.1	0.5	2.7	-1.6	0.3	0.3	0.3	0.4	0.4	-0.4	-1.1	0.3	0.3	0.5
Exposure to tobacco smoke at home	0.1	0.1	0.8	-0.6	-0.1	-0.1	-0.1	-0.0	0.1	-0.1	-0.9	0.0	-0.1	-0.5
Breastfed as a baby	0.1	0.1	0.4	0.3	-0.3	-0.2	-0.2	-0.3	-0.2	-0.1	-0.4	-0.2	-0.6	-0.5
Tense / ‘highly strung’	0.1	0.1	0.5	-0.5	-0.3	-0.3	-0.3	-0.2	-0.1	0.0	-0.6	-0.2	-0.1	-0.7
Qualifications: College or University degree	0.1	0.3	1.5	-0.1	-0.0	0.0	-0.1	0.3	0.2	-0.7	-1.2	0.0	-0.9	-0.5
Eye problems/disorders: None of the above	0.1	0.1	0.3	0.5	-0.2	-0.1	-0.2	-0.1	0.0	-0.1	-0.4	-0.1	-0.5	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.8	-0.1	-0.1	-0.1	-0.1	-0.1	0.1	-0.3	-0.9	-0.0	-0.3	0.0
Suffer from ‘nerves’	0.1	0.2	1.1	-0.6	0.0	0.0	-0.0	0.1	0.2	-0.2	-1.0	0.0	-0.1	-0.5
Leg pain on walking	0.1	0.2	0.6	-0.3	-0.2	-0.2	-0.3	-0.3	-0.6	-0.8	-0.1	-0.4	-0.6	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	1.2	-0.1	-0.0	-0.0	-0.0	0.1	0.1	-0.1	-1.1	0.1	-0.3	-0.4
Breast cancer (self-reported)	0.1	0.1	0.4	0.6	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0.5	-0.1	-0.4	0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	-0.2	-0.3	-0.3	-0.2	-0.3	-0.3	0.2	0.4	-0.2	-0.2	-0.3
Smoking status: Current	0.1	0.2	0.9	-0.6	-0.2	-0.3	-0.2	-0.4	-0.3	0.5	1.0	-0.3	0.5	-0.4
Average weekly champagne plus white wine intake	0.1	0.1	0.2	-0.3	-0.1	-0.1	-0.1	-0.1	-0.1	-0.4	-0.4	-0.1	-0.5	-0.3
Medication: Blood pressure	0.1	0.2	0.8	0.9	0.3	0.4	0.3	0.5	0.5	0.0	-0.3	0.4	-0.5	0.5
Number of operations (self-reported)	0.1	0.2	0.8	0.9	0.4	0.5	0.4	0.5	0.1	0.1	0.4	0.2	-0.2	0.4
Risk taking	0.1	0.1	0.6	0.7	-0.2	-0.1	-0.1	0.1	0.1	0.0	-0.1	-0.0	-0.8	-0.4
Age started oral contraceptive pill	0.1	0.1	0.4	-0.3	-0.3	-0.3	-0.3	-0.3	-0.1	-0.5	-0.6	-0.2	-0.5	0.1
Unable to work because of sickness or disability	0.1	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.1	0.4	0.9	0.0	0.0	-0.0
Myopia	0.1	0.1	0.7	0.1	-0.0	0.0	-0.0	0.0	0.1	-0.3	-0.9	0.1	-0.7	-0.3
Supplements: Calcium	0.1	0.1	0.6	0.0	-0.3	-0.3	-0.3	-0.3	-0.3	-0.4	-0.1	-0.4	-0.8	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	0.1	0.3	0.2	0.3	0.2	0.1	0.6	0.5	0.2	0.4	0.2
Schizophrenia (2018)	0.0	0.1	0.4	-0.3	-0.2	-0.2	-0.2	-0.3	-0.4	-0.1	0.6	-0.4	0.2	0.1
Ulcerative Colitis (UC)	0.0	0.0	0.2	0.2	0.1	0.1	-0.0	0.2	0.1	-0.2	0.2	-0.1	-0.4	0.2
HDL Cholesterol	0.0	0.1	0.4	0.4	0.2	0.1	0.1	0.2	0.1	-0.2	-0.6	0.1	0.4	0.1
Schizophrenia (2014)	0.0	0.1	0.6	-0.2	0.0	0.0	0.0	0.0	-0.3	0.3	0.8	-0.1	0.3	0.1
Blood Red Count	0.0	0.1	0.5	-0.3	-0.3	-0.3	-0.3	-0.5	-0.4	0.1	0.7	-0.3	0.4	-0.2
Heel T-Score	0.0	0.2	0.9	-0.5	-0.1	-0.1	-0.1	-0.4	-0.3	0.3	1.0	-0.1	0.3	0.3
Smoking Status	0.0	0.1	0.2	0.2	0.3	0.3	0.3	0.3	0.3	0.4	0.1	0.2	0.2	-0.0
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.2	0.5	-0.0	0.0	0.0	-0.1	-0.1	0.4	0.4	0.0	0.0	-0.1
Hair Pigment	0.0	0.1	0.4	0.6	0.2	0.2	0.2	0.4	0.3	0.3	0.3	0.2	0.1	0.1
Tanning	0.0	0.6	1.3	-0.7	-0.9	-0.9	-0.9	-1.1	-1.0	-0.2	0.5	-0.9	-0.3	-0.5
Average weekly fortified wine intake	0.0	0.0	0.1	0.2	0.2	0.2	0.2	0.1	-0.2	-0.2	-0.2	0.0	0.1	0.1
Exposure to tobacco smoke outside home	0.0	0.1	0.2	-0.2	-0.1	-0.1	-0.1	-0.2	-0.1	0.4	0.4	-0.1	0.1	-0.3
Comparative body size at age 10	0.0	0.1	0.4	0.4	-0.3	-0.2	-0.2	-0.3	-0.3	-0.1	0.1	-0.3	-0.6	-0.3
Medication: Omeprazole	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.2	-0.1	-0.1	0.1	-0.2	0.4
Heart disease (mother)	0.0	0.0	0.1	-0.3	-0.2	-0.3	-0.2	-0.2	0.1	-0.1	-0.3	-0.1	-0.3	-0.0
Illnesses of father: Heart disease	0.0	0.0	0.2	-0.1	-0.1	-0.1	-0.1	0.0	0.1	-0.4	-0.4	-0.0	-0.2	0.2
Friendships satisfaction	0.0	0.0	0.1	-0.4	-0.0	-0.0	-0.0	-0.0	-0.0	0.2	0.2	-0.0	-0.2	-0.3
Irritability	0.0	0.1	0.2	0.1	0.2	0.2	0.2	0.2	0.2	0.4	-0.0	0.2	0.1	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.0	0.1	0.3	0.3	0.1	0.2	0.1	0.2	0.1	-0.3	-0.2	0.1	-0.1	0.5

Hub : Genes

C2orf54

Models

Trait associations