TWAS hub - C7orf28A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0514	0.0197	1.2e-09	0.009	0.057	0.056	NA	0.049	5.1e-03	8.3e-12	1.6e-11	NA	3.0e-10
2	TCGA	Cervical Squamous Cell Carcinoma	0.0850	0.0470	8.1e-03	0.010	0.033	0.017	NA	0.012	1.0e-01	9.4e-03	4.8e-02	NA	7.8e-02
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0654	0.0281	4.9e-06	0.068	0.041	0.038	NA	0.062	4.5e-08	1.9e-05	3.4e-05	NA	1.6e-07
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0595	0.0249	1.3e-05	0.022	0.030	0.023	NA	0.022	1.4e-03	2.5e-04	1.0e-03	NA	1.5e-03
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0850	0.0450	2.6e-03	0.020	0.026	0.025	NA	0.011	2.5e-02	1.3e-02	1.4e-02	NA	7.2e-02
6	TCGA	Brain Lower Grade Glioma	0.0576	0.0256	7.3e-05	0.003	0.041	0.024	NA	0.016	1.2e-01	1.7e-05	8.5e-04	NA	5.3e-03
7	TCGA	Lung Adenocarcinoma	0.0672	0.0356	2.3e-04	0.036	0.038	0.018	NA	0.025	4.2e-05	2.9e-05	2.8e-03	NA	5.7e-04
8	TCGA	Pancreatic Adenocarcinoma	0.1170	0.0590	9.2e-03	0.002	0.010	-0.004	NA	0.008	2.5e-01	1.2e-01	5.2e-01	NA	1.4e-01
9	TCGA	Prostate Adenocarcinoma	0.0840	0.0337	2.3e-07	0.036	0.077	0.069	NA	0.060	1.2e-04	2.0e-08	1.1e-07	NA	7.6e-07
10	TCGA	Soft Tissue Sarcoma	0.0760	0.0420	2.1e-03	-0.003	0.019	0.007	NA	-0.003	5.8e-01	2.7e-02	1.1e-01	NA	5.7e-01
11	TCGA	Thyroid Carcinoma	0.1010	0.0380	2.5e-08	0.019	0.097	0.098	NA	0.092	5.0e-03	1.2e-09	8.2e-10	NA	3.1e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Commuting to job workplace: Cycle	6.9	8.3	12.4	3.3	2.9	2.1	2.9	2.7	3.0	2.8	2.9	2.3	3.0	3.5
Diabetes (father)	6.0	7.5	11.5	-2.9	-3.4	-3.2	-2.6	-2.3	-2.3	-2.8	-2.0	-1.6	-3.3	-3.0
Alzheimer’s Disease (including proxy)	5.8	8.4	10.4	2.9	3.2	2.8	3.1	3.1	2.7	3.1	2.7	2.8	2.1	3.2
Nervous feelings	5.7	10.6	14.3	-3.8	-3.4	-2.1	-3.7	-3.1	-3.7	-2.8	-3.7	-2.7	-2.4	-3.7
Myopia	5.2	7.5	14.7	3.5	2.8	1.4	2.4	2.3	2.8	2.6	2.5	1.8	3.8	3.1
Alzheimer’s Disease (in mother)	5.0	5.8	9.4	2.3	2.9	3.1	2.5	2.6	2.3	2.3	2.3	1.8	1.9	2.4
Heart attack/myocardial infarction (self-reported)	4.6	6.0	11.7	-3.1	-1.4	-0.1	-2.8	-2.4	-2.2	-1.9	-3.0	-3.4	-1.9	-2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	4.4	5.8	9.4	-2.9	-2.4	-1.3	-2.7	-2.6	-2.8	-1.6	-3.1	-2.0	-1.4	-2.7
Suffer from ‘nerves’	4.4	7.0	10.6	-3.1	-2.2	-0.9	-2.9	-2.4	-3.3	-2.5	-3.2	-2.7	-2.0	-3.0
Heart attack	4.2	5.4	10.7	-2.9	-1.4	-0.0	-2.7	-2.3	-2.2	-1.8	-2.9	-3.3	-1.7	-2.6
Medication: Ibuprofen (e.g. Nurofen)	4.0	5.0	6.7	-2.6	-2.1	-1.4	-2.5	-2.4	-2.3	-1.9	-2.6	-2.2	-1.8	-2.6
Frequency of depressed mood in last 2 weeks	3.9	5.5	9.1	-2.8	-2.1	-0.0	-2.5	-2.2	-3.0	-2.2	-2.9	-2.4	-1.4	-2.6
Ever unenthusiastic/disinterested for a whole week	3.6	4.5	10.0	-2.2	-1.8	-0.3	-2.2	-1.9	-3.2	-2.4	-2.8	-2.1	-1.1	-1.8
Qualifications: O levels/GCSEs or equivalent	3.6	5.8	9.4	3.0	1.6	1.2	2.4	2.4	2.3	1.8	2.7	2.4	2.9	3.1
Depression (Nagel 2018)	3.4	5.2	10.0	-2.7	-1.4	-0.3	-2.8	-2.0	-3.0	-1.7	-3.2	-2.6	-1.0	-2.5
Serious illness, injury or assault to yourself	3.4	4.1	6.4	-1.8	-1.8	-1.3	-2.1	-2.5	-2.2	-2.1	-2.3	-2.4	-0.8	-2.1
Cholesterol lowering medication	3.4	4.9	7.5	-2.3	-2.6	-0.8	-2.0	-2.4	-2.6	-2.7	-2.3	-2.0	-1.8	-2.4
Bilateral oophorectomy (both ovaries removed)	3.1	3.6	6.1	-2.2	-1.9	-0.7	-2.1	-1.0	-2.5	-2.4	-2.0	-1.6	-1.5	-2.1
Lung cancer (father)	3.1	3.6	5.4	1.7	2.0	1.7	2.0	2.3	1.4	2.2	1.6	2.2	1.2	2.3
Neuroticism (2016)	3.0	4.3	7.7	-2.6	-1.6	-0.2	-2.0	-1.6	-2.8	-2.0	-2.6	-1.9	-2.1	-2.1
Medication: Metformin	2.9	4.1	7.6	-2.6	-2.2	-1.6	-2.1	-2.1	-1.9	-1.2	-2.1	-1.1	-2.0	-2.8
Allergy	2.9	6.6	11.1	-3.3	-1.4	-0.6	-2.7	-2.5	-2.7	-1.8	-3.2	-2.9	-2.4	-3.2
Alcohol drinker status: Previous	2.9	3.3	5.5	-1.6	-2.2	-2.2	-1.6	-1.2	-2.0	-2.3	-1.4	-0.8	-2.3	-1.6
Other serious medical condition/disability diagnosed by doctor	2.6	3.3	6.8	-1.5	-1.9	-2.6	-1.7	-2.4	-1.8	-1.5	-1.9	-1.4	-1.1	-1.7
Hayfever/allergic rhinitis (self-reported)	2.5	3.4	6.8	2.3	1.4	1.1	1.6	1.7	1.5	1.7	1.7	1.8	2.6	2.3
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.0	4.1	-1.9	-1.9	-1.5	-1.5	-1.6	-1.9	-1.7	-1.6	-1.1	-2.0	-2.0
Age started oral contraceptive pill	2.5	3.1	5.3	-1.5	-2.3	-1.3	-1.7	-2.1	-2.2	-2.1	-1.9	-1.4	-0.6	-1.6
Asthma	2.3	4.5	8.6	2.9	0.9	1.0	2.3	1.8	1.9	1.2	2.4	2.2	2.7	2.8
Eye problems/disorders: Cataract	2.3	2.7	5.2	-1.4	-2.3	-2.3	-1.5	-1.9	-1.4	-1.7	-1.3	-0.9	-1.2	-1.7
Medication: Atorvastatin	2.3	2.9	6.0	-1.7	-1.8	-0.4	-1.2	-1.4	-1.8	-2.5	-1.3	-1.5	-2.2	-1.8
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	6.8	-2.6	-1.3	-0.3	-2.0	-1.3	-2.0	-1.3	-2.1	-1.6	-2.2	-2.2
Hearing difficulty/problems with background noise	2.2	3.5	9.8	-2.3	-1.8	-2.4	-1.8	-0.7	-1.7	-1.4	-1.4	-0.5	-3.1	-2.0
Neuroticism score	2.2	4.5	6.5	-2.4	-1.5	-0.6	-2.1	-2.0	-2.5	-2.3	-2.5	-2.5	-2.0	-2.1
Loneliness, isolation	2.2	3.1	5.7	-1.5	-1.2	-0.2	-1.8	-1.6	-2.3	-2.4	-2.1	-2.4	-0.6	-1.6
Long-standing illness, disability or infirmity	2.2	3.3	3.9	-1.9	-1.9	-1.4	-1.6	-2.0	-1.9	-2.0	-1.9	-1.6	-2.0	-1.8
Qualifications: A levels/AS levels or equivalent	2.1	4.6	8.0	2.6	1.9	0.7	2.1	2.3	2.5	1.6	2.6	1.8	1.8	2.8
Medication for pain relief, constipation, heartburn	2.1	3.6	8.5	2.5	1.1	-0.3	1.5	1.3	2.1	1.6	2.1	1.7	2.9	2.4
Medication: Aspirin	2.1	2.8	4.7	-2.1	-1.0	0.0	-1.8	-1.7	-1.5	-1.2	-2.0	-2.2	-1.4	-2.1
Ever taken oral contraceptive pill	2.1	2.4	3.6	-1.5	-1.7	-1.5	-1.5	-1.6	-0.6	-1.9	-0.9	-1.9	-1.7	-1.6
Worry (Nagel 2018)	2.0	4.1	7.1	-2.1	-1.8	-1.0	-2.4	-2.0	-2.7	-2.1	-2.6	-2.2	-0.8	-2.0
Lung FEV1/FVC ratio	2.0	10.1	19.7	-3.2	-2.7	-0.7	-2.7	-3.0	-4.4	-4.1	-3.6	-3.0	-2.7	-3.3
Chronic bronchitis/emphysema (mother)	2.0	2.3	3.9	-1.9	-1.5	-1.2	-1.5	-1.2	-2.0	-1.2	-1.7	-0.7	-1.7	-1.6
Overall health rating	2.0	4.2	11.1	-2.5	-2.0	-1.1	-1.5	-1.4	-2.6	-2.0	-2.0	-0.8	-3.3	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.1	6.6	2.1	2.4	1.6	2.1	2.0	2.6	2.2	2.2	1.3	1.2	2.2
Asthma (self-reported)	2.0	4.1	8.0	2.8	1.0	0.9	2.2	1.6	1.8	1.2	2.3	2.1	2.6	2.6
Medication: Aspirin	2.0	2.6	4.5	-1.9	-1.2	-0.1	-1.8	-1.7	-1.5	-1.3	-2.0	-2.1	-1.2	-2.0
Ever depressed for a whole week	2.0	2.5	3.6	-1.6	-1.7	-1.6	-1.8	-1.7	-1.9	-1.3	-1.9	-1.1	-0.8	-1.6
Alzheimer’s Disease (in father)	1.9	2.1	3.6	1.7	1.2	0.5	1.5	1.1	1.2	1.8	1.2	1.7	1.4	1.9
Number of incorrect matches in round	1.9	3.1	5.0	1.8	1.6	2.2	1.9	1.6	2.2	1.4	2.1	1.1	1.5	1.6
Medication: Cholesterol lowering	1.9	2.9	5.0	-1.6	-1.0	-0.6	-1.4	-1.9	-2.0	-2.2	-1.9	-2.2	-1.5	-1.7
High cholesterol (Self-reported)	1.9	3.4	8.4	-1.5	-1.9	-0.8	-1.4	-1.8	-2.5	-2.9	-1.9	-1.8	-1.4	-1.7
Type 2 Diabetes (T2D) (2018)	1.8	3.3	5.2	-1.7	-2.0	-1.7	-1.8	-1.8	-2.3	-2.0	-2.0	-1.2	-1.0	-2.2
Ever used hormone-replacement therapy (HRT)	1.8	2.2	5.5	-1.1	-1.5	-0.6	-1.5	-1.2	-2.3	-2.2	-1.8	-1.4	-0.3	-1.2
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	4.5	1.8	1.7	1.3	1.9	1.9	1.1	1.7	1.5	2.1	1.6	1.8
Qualifications: nursing, teaching	1.7	2.6	4.8	1.6	1.5	-0.4	0.9	1.6	2.1	2.2	1.6	1.4	1.9	1.6
Relative age voice broke	1.6	2.4	5.0	-1.9	-1.5	-2.2	-1.9	-1.2	-0.7	-0.9	-1.0	-1.2	-1.9	-1.8
Age at first live birth	1.6	2.8	5.2	2.3	1.4	0.2	1.7	1.8	1.9	1.1	2.0	1.4	1.4	2.0
Medication: Ibuprofen	1.6	1.9	2.7	-1.6	-1.3	-1.2	-1.5	-1.4	-1.1	-1.0	-1.4	-1.3	-1.6	-1.6
Hearing difficulty/problems: Yes	1.5	2.4	5.4	-1.4	-1.9	-2.3	-1.5	-0.8	-1.7	-1.6	-1.1	-0.3	-1.6	-1.5
Hayfever, allergic rhinitis or eczema	1.5	3.2	5.0	2.2	1.0	0.4	1.8	1.7	2.0	1.3	2.2	1.9	1.9	2.2
Worrier / anxious feelings	1.5	2.9	5.4	-1.1	-2.0	-1.4	-1.6	-2.2	-1.8	-2.3	-1.7	-1.9	-0.8	-1.3
Pulse rate	1.5	2.5	5.9	-1.8	-0.5	-0.5	-1.8	-2.2	-1.3	-0.7	-2.1	-2.4	-0.6	-1.9
Pulse wave reflection index	1.5	1.8	3.8	1.6	-0.1	-0.3	1.4	0.9	1.8	1.0	2.0	1.9	1.0	1.4
Loud music exposure frequency	1.5	1.6	2.7	-1.3	-1.0	-1.2	-1.4	-0.8	-1.6	-1.5	-1.3	-1.2	-1.3	-1.0
Alcohol intake frequency.	1.4	3.2	6.8	-2.6	-1.6	-0.5	-1.8	-1.7	-1.7	-0.9	-2.0	-1.2	-2.2	-2.5
Medication: Gliclazide	1.4	1.6	2.6	-1.3	-1.5	-1.1	-1.1	-1.4	-1.3	-1.2	-1.1	-0.7	-1.2	-1.6
Townsend deprivation index at recruitment	1.3	1.8	3.9	-1.9	-1.4	-0.6	-1.2	-1.3	-1.2	-0.8	-1.3	-0.8	-2.0	-1.7
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	3.6	-1.2	-1.0	-0.3	-1.1	-0.9	-1.9	-1.7	-1.4	-1.1	-1.2	-1.3
Father’s age at death	1.3	1.8	4.1	2.0	1.0	0.7	1.6	0.7	1.0	0.6	1.4	1.1	1.8	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	3.7	1.9	0.7	-0.5	1.3	1.3	1.3	0.3	1.7	1.2	0.8	1.7
Medication for hormone replacement therapy	1.2	1.4	2.6	-1.2	-1.5	-1.6	-1.3	-1.1	-1.3	-1.1	-1.1	-0.6	-0.8	-1.1
Qualifications: CSEs or equivalent	1.2	1.6	4.5	-1.4	-1.4	-1.4	-0.8	-1.0	-1.1	-1.0	-0.8	-0.1	-2.1	-1.7
Depression (self-reported)	1.2	1.5	2.5	-1.3	-1.4	-1.2	-1.1	-1.3	-1.6	-1.1	-1.3	-0.6	-0.9	-1.2
Medication: Amlodipine	1.2	1.7	5.2	-1.8	-0.3	-0.4	-1.1	-1.2	-0.8	-0.8	-1.2	-1.5	-2.3	-1.7
Diabetes diagnosed by doctor	1.2	2.0	3.6	-1.7	-1.5	-1.1	-1.3	-1.5	-1.5	-1.1	-1.5	-0.9	-1.4	-1.9
Supplements: Calcium	1.2	1.3	1.9	1.4	1.1	0.1	1.0	1.2	1.3	1.3	1.2	1.2	1.2	1.2
Lupus	1.1	1.6	3.1	-0.8	-1.4	-1.8	-1.1	-1.6	-1.2	-1.6	-1.0	-1.3	-1.0	-0.8
Medication: Simvastatin	1.1	1.7	2.4	-1.3	-1.1	-0.7	-1.1	-1.5	-1.5	-1.4	-1.5	-1.3	-1.0	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	3.7	-1.9	-1.1	-1.2	-1.2	-0.9	-1.4	-0.5	-1.3	-0.3	-1.9	-1.6
Comparative body size at age 10	1.1	3.0	5.4	2.3	1.7	1.5	2.0	1.6	1.3	1.1	1.7	1.6	2.3	1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	4.7	-1.2	-1.3	-1.7	-0.6	-0.8	-0.7	-0.9	-0.5	-0.0	-2.2	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	3.8	-1.4	-1.2	-0.7	-0.8	-1.0	-1.0	-0.8	-1.0	-0.5	-1.9	-1.1
Neuroticism	1.0	2.4	4.2	-1.6	-1.2	-0.5	-1.6	-1.8	-1.6	-1.6	-1.8	-2.0	-1.2	-1.4
Supplements: Zinc	1.0	1.0	1.8	1.1	1.4	1.3	0.7	1.3	0.5	0.7	0.6	0.4	1.4	1.2
Age when periods started (menarche)	1.0	2.5	5.7	-2.3	-0.5	0.1	-1.8	-1.3	-0.8	-0.8	-1.6	-2.4	-1.6	-2.1
Diabetes (self-reported)	1.0	1.6	2.8	-1.3	-1.4	-1.1	-1.0	-1.6	-1.4	-0.8	-1.4	-0.5	-1.0	-1.7
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	2.7	1.4	0.6	0.1	1.0	1.4	1.6	1.5	1.6	1.6	1.4	1.4
Wheeze or whistling in the chest in last year	1.0	1.8	4.6	0.8	1.6	1.0	1.1	1.6	1.5	2.1	1.2	1.4	0.4	1.2
Family relationship satisfaction	1.0	1.3	3.0	1.0	0.8	1.3	1.2	1.1	1.7	0.7	1.6	0.6	0.5	1.1
Illnesses of father: None of the above (group 1)	1.0	1.2	2.5	1.0	0.8	1.6	1.2	1.3	0.8	0.7	1.2	1.1	1.1	1.0
Financial situation satisfaction	1.0	1.3	3.0	-1.3	-1.7	-0.7	-0.8	-0.4	-1.2	-1.4	-0.6	-0.0	-1.7	-1.2
Depressed Affect (Nagel 2018)	0.9	1.9	3.7	-1.6	-0.6	0.2	-1.5	-1.0	-1.7	-1.4	-1.8	-1.9	-1.2	-1.4
Number of treatments/medications taken	0.9	1.7	2.2	-1.3	-1.4	-1.1	-1.4	-1.4	-1.5	-1.2	-1.5	-1.1	-1.0	-1.4
Supplements: Glucosamine	0.9	1.2	2.8	1.2	0.9	1.7	1.1	0.8	0.9	0.8	1.0	0.7	1.3	1.0
Length of working week for main job	0.9	1.0	4.0	-0.9	-1.4	-2.0	-1.2	-0.2	-0.1	-0.9	-0.1	-0.3	-1.2	-1.0
Shortness of breath walking on level ground	0.9	1.0	1.9	0.7	1.3	1.1	1.2	1.4	0.9	0.2	1.1	0.5	-1.0	1.0
Pulse rate, automated reading	0.9	2.9	6.2	-2.1	-1.2	-0.4	-1.9	-2.5	-1.3	-0.6	-2.1	-2.2	-0.3	-2.0
Commuting to job workplace: Walk	0.9	1.0	3.5	1.0	1.5	1.9	0.9	0.2	-0.3	0.4	-0.1	-0.2	1.3	1.2
Fractured/broken bones in last 5 years	0.9	1.1	2.9	-0.8	-0.9	-0.2	-1.2	-1.7	-0.9	-0.4	-1.5	-1.5	0.6	-0.9
Tanning	0.8	10.3	22.1	-2.6	-3.8	-2.7	-3.1	-2.8	-4.0	-4.7	-3.0	-2.7	-2.3	-2.8
Hand grip strength (left)	0.8	2.0	4.2	1.5	0.7	0.4	2.0	1.2	1.8	1.2	2.0	2.1	0.0	1.2
Relative age of first facial hair	0.8	1.7	3.5	-1.9	-1.5	-0.7	-1.4	-0.9	-1.2	-1.0	-1.1	-0.7	-1.6	-1.8
Diabetes (mother)	0.8	1.0	5.7	-1.6	0.1	0.2	-0.4	-0.3	-0.5	0.3	-0.8	-0.2	-2.4	-1.3
Hand grip strength (right)	0.8	2.1	4.6	1.6	0.5	-0.1	1.9	1.2	1.7	1.0	2.1	2.1	0.3	1.3
Illnesses of siblings	0.8	1.1	2.5	-1.0	-0.3	-0.1	-1.0	-1.0	-1.6	-1.2	-1.4	-1.4	-0.4	-0.9
High blood pressure (siblings)	0.8	1.2	2.7	0.8	0.4	0.4	1.0	1.2	1.4	1.5	1.4	1.6	0.4	0.9
Medication: Blood pressure	0.8	1.4	2.3	-1.1	-0.7	-0.5	-0.9	-1.5	-1.4	-1.3	-1.4	-1.4	-1.2	-1.1
Miserableness	0.8	1.3	2.3	-1.3	-0.8	-0.4	-1.0	-1.1	-1.5	-1.3	-1.3	-1.2	-1.5	-0.9
Blood White Count	0.7	4.9	29.7	-3.0	-1.7	-1.7	-1.0	-0.9	-0.6	-0.4	-0.7	0.2	-5.5	-2.7
Respiratory disease	0.7	1.6	4.2	1.8	-0.1	0.1	1.1	0.9	1.0	0.3	1.4	1.4	2.0	1.6
Taking other prescription medications	0.7	1.1	1.8	-1.3	-0.9	-1.0	-1.1	-1.1	-1.0	-0.4	-1.2	-0.6	-1.1	-1.3
Medication: Atenolol	0.7	0.8	2.5	-0.8	-0.3	-0.9	-1.3	-0.6	-0.8	-0.9	-1.1	-1.6	-0.5	-0.7
Qualifications: None of the above	0.7	1.6	7.5	-1.6	0.3	1.7	-0.1	-0.3	-1.1	-0.6	-1.0	-0.7	-2.7	-1.2
Falls in the last year	0.7	0.9	1.6	-1.1	-0.9	-0.7	-1.2	-1.1	-1.1	-0.6	-1.2	-0.9	-0.3	-1.1
Happiness	0.7	0.8	1.9	-1.0	-1.0	-0.7	-1.2	-0.9	-0.2	-0.9	-0.7	-1.4	-0.7	-0.9
Noisy workplace	0.7	0.8	2.1	0.6	0.5	0.7	0.8	1.4	0.8	1.0	1.0	1.3	0.2	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	4.5	-1.0	-0.4	-1.3	-0.4	0.6	-0.6	-0.3	-0.1	0.6	-2.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	2.6	-1.1	-0.7	0.4	-1.1	-0.7	-1.6	-1.1	-1.3	-0.9	-0.1	-1.1
Number of children fathered	0.7	0.8	1.5	1.2	0.5	-0.3	1.0	1.2	0.7	0.1	1.2	1.1	0.1	1.1
Emphysema/chronic bronchitis	0.7	0.8	2.0	1.1	0.6	-0.2	1.2	0.9	0.7	0.5	1.1	1.4	0.1	1.0
Neck or shoulder pain in last month	0.7	1.0	1.9	-1.2	-0.7	-0.4	-1.3	-1.0	-1.1	-0.8	-1.4	-1.3	-0.5	-1.0
Migraine (self-reported)	0.7	0.8	2.0	-0.7	-1.0	-0.9	-1.0	-1.4	-0.9	-0.5	-1.1	-0.8	-0.1	-0.9
Mean time to correctly identify matches	0.7	1.3	3.5	-0.6	-1.0	-1.3	-1.3	-1.8	-0.5	-1.1	-1.1	-1.9	-0.0	-0.6
Smoking status: Previous	0.7	1.1	2.1	1.4	0.6	0.6	1.4	0.5	1.2	0.6	1.2	0.9	0.8	1.4
Smoking status: Current	0.7	1.1	2.4	-1.3	-0.6	-0.3	-1.5	-0.9	-1.0	-0.7	-1.4	-1.6	-0.4	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.4	-0.7	-1.0	-1.9	-0.6	0.0	-0.7	-0.9	-0.2	0.2	-1.5	-0.9
Pain experienced in last month	0.7	1.1	3.1	1.7	0.1	-1.0	0.7	0.2	1.1	0.3	1.1	0.6	1.8	1.3
Neuroticism (Nagel 2018)	0.6	1.4	3.0	-1.0	-0.6	0.3	-1.3	-0.9	-1.7	-1.5	-1.6	-1.7	-0.2	-0.9
Breast Cancer	0.6	1.5	3.8	-1.6	-0.7	-1.3	-1.3	-0.8	-0.5	-0.4	-1.0	-1.0	-1.9	-1.6
Allergy or Eczema	0.6	1.5	3.0	1.6	0.5	0.0	1.2	1.2	1.6	0.6	1.7	1.3	1.1	1.5
Current tobacco smoking	0.6	1.0	1.9	-1.2	-0.5	-0.4	-1.4	-0.7	-1.0	-0.6	-1.3	-1.3	-0.5	-1.1
Had menopause	0.6	0.8	2.0	-0.3	-0.8	-1.1	-0.8	-1.0	-1.4	-1.1	-1.1	-0.7	0.1	-0.3
Hair/balding pattern: Pattern 3	0.6	0.8	2.1	-1.4	-0.2	1.0	-0.7	-0.4	-0.1	-0.6	-0.5	-1.4	-1.3	-1.1
Medication: Omeprazole	0.6	0.7	4.3	-0.4	-0.6	-2.1	-0.3	0.2	0.0	-0.3	0.2	0.5	-1.4	-0.5
Back pain experienced in last month	0.6	0.8	3.4	-1.4	-0.3	0.6	-0.4	-0.0	-1.2	-0.3	-0.9	0.0	-1.8	-0.9
Vascular/heart problems diagnosed by doctor	0.6	1.7	3.2	1.4	1.3	0.7	1.1	1.1	1.4	1.5	1.2	1.1	1.8	1.3
Basal cell carcinoma (self-reported)	0.6	0.8	1.7	-0.6	-1.3	-0.7	-0.8	-0.9	-1.3	-0.9	-0.9	-0.2	0.5	-0.8
BMI	0.5	2.9	6.5	-2.1	-1.1	-0.7	-1.4	-1.6	-2.5	-0.7	-2.3	-0.6	-1.6	-2.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	3.2	-0.3	0.8	0.8	0.6	0.2	0.6	1.8	0.2	0.9	-0.3	0.0
Medication: Co-codamol	0.5	0.6	2.5	0.7	0.6	1.0	0.5	-0.1	0.5	1.1	0.1	0.3	1.6	0.8
Severe depression (siblings)	0.5	0.5	1.5	0.5	0.3	0.0	0.5	0.9	0.8	1.1	0.9	1.2	0.5	0.7
Pack years adult smoking proportion	0.5	0.8	3.0	1.1	0.6	0.2	1.3	1.1	0.0	0.4	0.8	1.7	-0.1	0.9
Maternal smoking around birth	0.5	0.7	1.3	1.0	1.1	0.6	1.1	0.5	0.9	1.0	0.7	0.8	0.4	0.7
Stomach or abdominal pain in last month	0.5	0.6	2.3	-1.0	-1.0	-0.8	-0.4	-0.2	-0.2	-0.2	-0.1	0.4	-1.5	-1.0
Chronic bronchitis/emphysema (father)	0.5	0.6	1.6	-0.6	0.3	0.5	-0.8	-0.8	-0.6	0.3	-1.3	-1.2	0.8	-0.2
Alcohol usually taken with meals	0.5	0.8	2.1	0.9	-0.3	-0.7	0.7	0.6	1.3	0.4	1.5	1.2	0.5	0.8
Financial difficulties in last 2 years	0.5	0.7	1.8	-1.3	-1.1	-0.8	-0.8	-0.4	-0.7	-0.2	-0.7	0.1	-1.3	-0.9
Number of live births	0.5	0.7	2.7	0.9	-0.9	-1.6	-0.2	-0.3	-0.7	-1.2	-0.1	0.2	1.0	0.5
Birth weight of first child	0.5	0.9	2.1	-0.9	-0.3	-1.2	-1.0	-0.7	-1.5	-0.4	-1.4	-0.6	-0.8	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.4	-0.5	-1.2	-1.0	-0.4	-1.6	-0.8	-1.4	-0.7	-0.9	-1.0	-1.0
Qualifications: College or University degree	0.5	1.5	5.3	1.6	0.5	-0.7	0.6	0.5	1.5	1.2	1.1	0.7	2.3	1.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.6	0.5	-0.1	-0.3	0.4	0.8	1.0	1.1	0.9	1.3	0.5	0.8
Angina (self-reported)	0.5	0.6	1.2	-0.8	-1.1	-0.2	-0.7	-1.1	-1.1	-0.7	-0.9	-0.5	-0.2	-0.8
Medication: Seretide 50 evohaler	0.5	0.6	1.2	0.6	0.8	0.5	1.1	0.8	0.7	0.9	0.8	1.1	-0.4	0.7
Heart disease (mother)	0.5	0.6	1.7	0.2	-1.0	-1.3	-0.6	-0.9	-0.6	-0.4	-0.7	-0.2	1.1	-0.2
Age at last live birth	0.5	0.8	1.5	0.9	0.8	-0.2	0.6	1.2	1.0	1.0	1.0	1.0	0.5	0.9
Medication: Lisinopril	0.5	0.7	2.4	-0.5	0.1	0.8	-0.3	-0.9	-0.8	-1.1	-0.9	-1.5	-0.8	-0.4
Angina	0.4	0.5	1.2	-0.8	-0.9	0.1	-0.6	-1.1	-0.9	-0.6	-0.9	-0.6	-0.2	-0.7
Average weekly fortified wine intake	0.4	0.5	1.3	0.8	0.2	-0.1	0.8	0.4	0.5	0.7	0.7	1.1	0.8	0.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	2.2	0.7	-0.9	-1.0	-0.1	-0.4	0.1	-0.5	0.3	0.1	1.5	0.3
Past tobacco smoking	0.4	0.7	1.5	-1.1	-0.6	-0.3	-1.1	-0.6	-1.2	-0.6	-1.1	-0.6	-0.3	-1.2
Pain all over the body in last month	0.4	0.4	1.1	-0.6	-0.0	0.9	-0.4	-0.2	-1.0	-0.7	-0.8	-0.7	-0.2	-0.5
Fluid intelligence score	0.4	0.9	1.9	-0.5	-0.8	-0.9	-1.1	-0.9	-0.8	-1.4	-0.8	-1.2	0.4	-1.0
Arm fat percentage (right)	0.4	1.7	4.7	-1.6	-0.4	-0.5	-0.9	-0.6	-1.8	-1.0	-1.6	-0.6	-2.2	-1.6
Time employed in main current job	0.4	0.5	1.3	-0.9	0.3	1.1	-0.3	-0.6	-0.1	-0.0	-0.6	-1.0	-0.7	-0.8
Alcohol intake versus 10 years previously	0.4	0.6	1.6	-1.3	-0.8	0.1	-0.6	-1.1	0.7	0.9	-0.4	-0.5	-0.7	-1.0
Illnesses of mother	0.4	0.5	1.3	0.3	0.5	1.1	0.6	0.8	1.1	0.5	1.0	0.3	-0.1	0.5
Arm fat mass (right)	0.4	1.6	4.4	-1.7	-0.2	-0.2	-0.8	-0.6	-1.8	-0.5	-1.6	-0.3	-2.1	-1.7
Hair/balding pattern: Pattern 4	0.4	1.0	2.2	1.3	0.6	-0.0	0.6	0.9	1.3	0.9	1.1	0.7	1.5	1.2
Peak expiratory flow (PEF)	0.4	0.8	1.9	0.7	0.8	1.3	1.4	0.9	0.7	0.5	1.0	1.0	-0.1	0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.2	-0.6	0.4	-0.0	-0.2	0.5	-1.2	-0.9	-0.6	-0.2	-1.5	-0.5
Medication: Paracetamol	0.4	0.6	1.8	-0.7	0.3	1.3	-0.4	-0.2	-1.1	-0.6	-1.0	-1.0	-0.4	-0.6
Glaucoma (self-reported)	0.4	0.5	1.0	0.9	0.9	1.0	0.7	0.9	0.3	-0.3	0.6	0.0	0.3	0.8
Forced vital capacity (FVC), Best measure	0.4	1.3	6.2	0.4	1.5	2.5	0.8	0.5	1.2	1.4	0.6	-0.1	0.9	0.7
Body fat percentage	0.4	1.5	3.6	-1.4	-0.4	-0.5	-0.9	-0.7	-1.9	-0.9	-1.6	-0.6	-1.7	-1.4
Leg fat percentage (right)	0.4	1.3	5.5	-1.5	-0.4	-0.2	-0.5	-0.4	-1.6	-0.7	-1.2	-0.1	-2.3	-1.4
Worry too long after embarrassment	0.4	0.7	2.9	-0.1	-1.1	-1.7	-0.5	-0.8	-0.8	-1.1	-0.5	-0.3	-0.5	-0.3
Health satisfaction	0.4	0.6	1.4	0.3	0.6	0.3	0.6	1.2	1.0	0.8	1.0	0.9	-0.3	0.8
Had major operations	0.4	0.5	1.7	-0.1	1.0	1.3	0.1	0.8	0.5	1.1	0.1	-0.0	0.5	0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.6	0.6	-1.0	-0.1	0.6	0.5	0.5	-0.3	1.0	1.3	0.2	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	2.2	-0.6	0.4	0.7	0.2	1.0	0.0	-0.0	0.2	0.3	-1.5	-0.3
Illnesses of father: Heart disease	0.4	0.6	1.4	-0.7	-0.5	-1.2	-0.6	-1.0	-0.3	-0.4	-0.7	-0.7	-1.2	-0.7
Arm fat percentage (left)	0.4	1.5	3.5	-1.4	-0.3	-0.4	-1.0	-0.7	-1.9	-0.8	-1.7	-0.6	-1.6	-1.5
Mineral and other dietary supplements	0.4	0.5	3.6	-0.8	-0.5	-0.8	-0.2	0.1	-0.2	-0.2	-0.0	0.3	-1.9	-0.3
Commuting to job workplace: Public transport	0.4	0.5	1.4	0.8	1.1	0.4	0.3	0.5	0.5	0.4	0.4	-0.2	1.2	0.7
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.0	-0.0	0.6	0.8	0.9	0.7	0.4	0.6	0.6	0.9	-1.0	0.3
Illnesses of father: High blood pressure	0.4	0.5	2.1	-0.4	-0.6	-1.1	-0.1	-0.1	-0.7	-0.8	-0.1	0.4	-1.4	-0.7
Alcohol drinker status: Never	0.4	0.5	2.3	-0.2	0.7	1.5	0.0	0.0	0.2	1.1	-0.3	-0.1	1.0	0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.4	0.4	0.9	1.2	0.7	0.9	0.8	0.7	0.8	0.4	0.0	0.8
Pack years of smoking	0.4	0.6	2.5	1.0	0.4	0.1	1.2	0.9	-0.1	0.2	0.7	1.6	-0.0	0.8
Intelligence (Savage-Jansen 2018)	0.3	0.8	4.0	0.9	-1.1	-1.1	-0.3	-0.6	-0.0	-0.9	0.2	-0.3	2.0	0.3
Ulcerative Colitis (UC)	0.3	0.6	1.3	-0.9	-0.4	0.5	-0.9	-0.9	-0.5	-0.3	-0.9	-1.1	0.2	-1.0
Ovarian Cancer	0.3	0.4	1.0	0.0	0.1	0.4	0.7	0.5	0.6	0.7	0.6	1.0	-0.9	0.0
HbA1C	0.3	0.3	1.2	-0.3	0.3	0.6	-0.6	-0.5	-0.3	0.0	-0.7	-1.1	0.8	-0.4
Blood Platelet Count	0.3	3.2	7.0	1.8	2.1	2.6	2.2	2.2	1.5	0.7	1.9	1.2	0.5	1.7
Chronotype (morning person)	0.3	0.7	1.8	1.3	0.7	-0.0	0.9	0.8	0.6	0.1	0.8	0.7	0.9	1.3
Sensitivity / hurt feelings	0.3	0.6	0.9	-0.8	-0.6	-0.4	-0.8	-0.7	-0.9	-0.7	-0.9	-0.7	-0.6	-0.7
Trunk fat percentage	0.3	1.3	3.7	-1.2	-0.3	-0.3	-0.9	-0.8	-1.9	-0.9	-1.7	-0.8	-1.2	-1.3
Fed-up feelings	0.3	0.5	1.3	-1.0	0.3	0.8	-0.5	-0.1	-0.5	0.0	-0.7	-0.7	-1.1	-0.7
High blood pressure	0.3	1.0	2.5	-0.8	-0.9	-0.6	-0.5	-0.8	-1.1	-1.5	-0.8	-0.7	-1.6	-0.9
Body mass index (BMI)	0.3	1.3	3.6	-1.5	-0.5	-0.5	-0.7	-0.6	-1.7	-0.5	-1.4	0.0	-1.9	-1.6
Trunk fat mass	0.3	1.1	2.9	-1.4	-0.0	0.0	-0.8	-0.5	-1.7	-0.4	-1.6	-0.4	-1.4	-1.4
Hair/balding pattern: Pattern 2	0.3	0.4	1.7	0.5	-0.7	-1.3	-0.1	-0.3	-0.8	-1.2	-0.2	0.1	0.3	0.2
Forced vital capacity (FVC)	0.3	1.0	5.6	0.2	1.2	2.4	0.8	0.4	0.9	1.2	0.5	-0.0	0.9	0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.1	-1.1	-0.9	-0.3	-1.1	-0.5	-0.3	-0.4	-0.7	-0.8	-0.6	-0.7
Pulse wave Arterial Stiffness index	0.3	0.3	1.1	-0.1	-0.5	-0.5	0.5	-0.8	0.7	0.3	0.4	0.3	-1.0	-0.1
Blood clot in the leg (DVT)	0.3	0.4	1.0	0.3	0.7	1.0	0.7	0.8	0.6	0.5	0.7	0.5	-0.2	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.5	-0.1	0.8	1.0	0.2	1.2	0.5	0.4	0.4	0.1	-0.5	0.6
Birth weight	0.3	0.6	1.8	1.3	0.5	0.1	1.0	0.1	0.5	0.2	0.7	0.6	1.1	1.0
Pulse wave peak to peak time	0.3	0.3	1.0	0.1	0.6	0.6	-0.4	0.8	-0.6	-0.3	-0.3	-0.3	1.0	0.2
Whole body fat mass	0.3	1.3	3.1	-1.4	-0.2	-0.2	-0.7	-0.6	-1.8	-0.4	-1.5	-0.2	-1.8	-1.4
Leg fat mass (right)	0.3	1.3	5.1	-1.6	-0.4	-0.4	-0.6	-0.4	-1.6	-0.3	-1.3	0.2	-2.3	-1.5
Leg pain on walking	0.3	0.4	1.7	-0.7	0.4	1.3	0.1	0.2	-0.6	0.1	-0.5	-0.0	-0.8	-0.5
Knee pain experienced in last month	0.3	0.5	2.1	-1.0	0.3	1.4	-0.2	-0.1	-0.6	0.1	-0.7	-0.5	-0.7	-0.8
Illnesses of siblings: Diabetes	0.3	0.3	1.5	0.2	0.6	1.2	0.2	0.1	0.4	0.7	-0.0	-0.1	1.0	0.1
Mood swings	0.3	0.5	3.3	-0.4	0.9	1.8	0.3	0.6	0.0	0.3	-0.0	-0.2	-1.0	-0.1
Medication for cholesterol	0.3	0.5	1.0	0.8	1.0	0.5	0.8	0.6	0.8	0.7	0.7	0.4	0.4	0.7
Osteoarthritis (self-reported)	0.3	0.4	1.3	-0.9	0.1	0.1	-0.1	0.4	0.3	1.1	-0.1	0.7	-1.0	-0.6
Arm fat mass (left)	0.3	1.2	2.9	-1.4	-0.2	-0.2	-0.7	-0.4	-1.7	-0.4	-1.4	-0.2	-1.7	-1.5
Average weekly champagne plus white wine intake	0.3	0.5	2.8	-0.6	0.2	0.1	-0.1	0.4	-0.9	-0.9	-0.3	-0.1	-1.7	-0.2
Wears glasses or contact lenses	0.3	0.3	1.7	0.7	-0.1	-1.3	-0.0	0.1	0.8	0.0	0.6	0.1	0.6	0.4
Hearing aid user	0.3	0.3	0.7	0.8	0.0	0.2	0.6	0.7	0.5	-0.0	0.9	0.6	0.5	0.8
Leg fat percentage (left)	0.3	0.9	4.5	-1.2	-0.4	-0.3	-0.3	-0.3	-1.2	-0.6	-0.9	0.1	-2.1	-1.2
Irritability	0.3	0.6	3.6	-0.1	0.7	1.9	0.1	0.1	-0.1	-0.7	-0.2	-1.2	-0.4	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.9	0.9	-0.2	-0.7	0.4	0.1	-0.1	0.0	0.3	0.8	1.0	0.8
Leg fat mass (left)	0.3	1.2	5.1	-1.4	-0.4	-0.5	-0.4	-0.3	-1.3	-0.2	-1.0	0.4	-2.3	-1.4
Arm predicted mass (left)	0.3	1.3	3.8	-1.8	-0.4	-0.1	-0.7	-0.5	-1.4	0.1	-1.2	0.1	-2.0	-1.8
Crohns Disease (2017)	0.2	0.4	1.2	-0.1	0.6	1.1	0.6	0.7	0.5	0.3	0.6	0.3	-0.9	0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.4	0.0	-0.3	-0.7	-1.0	-0.3	-0.4	-0.9	-0.5	-1.1	1.2	-0.3
Fasting Glucose	0.2	0.3	0.9	0.3	0.4	0.0	0.4	0.3	0.9	0.9	0.7	0.3	0.0	0.0
Blood Red Count	0.2	1.8	3.3	-1.6	-0.2	1.5	-0.9	-1.3	-1.6	-0.8	-1.8	-1.7	-1.0	-1.4
Height	0.2	4.4	9.4	1.5	2.6	2.6	2.0	2.0	1.8	3.1	1.5	2.0	1.6	1.8
Smoking Status	0.2	0.4	0.9	-0.8	-0.4	0.4	-0.6	-0.9	-0.5	-0.2	-0.9	-0.9	-0.2	-0.7
Cardiovascular Disease	0.2	0.7	2.5	-0.3	-1.1	-0.8	-0.1	-0.2	-1.1	-1.6	-0.2	0.2	-1.3	-0.5
Hypothyroidism (self reported)	0.2	0.4	1.0	-0.4	-0.6	-0.4	-0.0	-1.0	-0.6	-0.7	-0.4	-0.3	-0.8	-0.7
Average weekly spirits intake	0.2	0.2	0.6	0.1	0.5	0.5	0.4	0.8	-0.2	-0.1	0.2	0.4	-0.8	0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	-0.4	-0.4	-0.5	-0.2	-0.2	-0.8	-0.4	-0.4	0.3	-0.4	-0.4
Waist circumference	0.2	0.9	2.5	-1.2	-0.4	-0.1	-0.6	-0.7	-1.6	-0.2	-1.4	-0.1	-1.1	-1.3
Mouth/teeth dental problems	0.2	0.4	1.7	-0.3	-0.4	-0.1	-0.3	-1.3	-0.1	-0.6	-0.4	-1.0	0.0	-0.7
Weight	0.2	1.1	2.4	-1.5	-0.0	0.1	-0.7	-0.5	-1.6	0.1	-1.5	-0.0	-1.5	-1.6
Impedance of arm (right)	0.2	0.9	2.1	1.1	1.1	1.3	0.5	0.6	0.8	0.2	0.5	-0.5	1.5	1.4
Medication: Lansoprazole	0.2	0.2	0.7	0.1	0.4	0.6	0.5	0.1	0.1	-0.5	0.2	-0.3	-0.9	0.4
Prospective memory result	0.2	0.2	0.8	0.4	-0.2	-0.6	0.0	0.2	0.9	0.7	0.6	0.4	0.5	0.5
Impedance of arm (left)	0.2	1.1	5.8	1.2	0.9	1.0	0.2	0.2	0.5	0.1	0.1	-0.8	2.4	1.4
Gout (self-reported)	0.2	0.3	0.6	-0.1	-0.5	-0.3	-0.6	-0.7	-0.7	-0.6	-0.7	-0.7	0.6	0.1
Arm fat-free mass (right)	0.2	1.0	2.5	-1.6	-0.5	-0.4	-0.7	-0.6	-1.2	0.3	-1.2	0.2	-1.4	-1.6
Number of full brothers	0.2	0.3	1.1	0.8	0.2	-0.1	0.5	0.5	0.1	-0.6	0.6	0.2	0.4	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.7	0.3	-0.8	-0.4	-0.0	-0.4	-0.6	-0.4	-0.2	0.3	0.8	0.3
Medication: Allopurinol	0.2	0.3	0.7	-0.5	-0.4	-0.1	-0.6	-0.9	-0.6	-0.3	-0.8	-0.8	0.1	-0.3
Number of full sisters	0.2	0.3	0.8	0.3	0.9	-0.1	0.5	0.3	0.6	0.8	0.4	0.3	-0.2	0.5
Hypertension (Self-reported)	0.2	0.5	1.5	-0.5	-0.7	-0.3	-0.1	-0.6	-0.7	-1.2	-0.4	-0.4	-1.2	-0.5
Average weekly red wine intake	0.2	0.3	1.2	0.2	-0.5	-1.1	-0.6	0.1	-0.7	-1.0	-0.3	-0.3	0.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.5	-0.2	0.7	0.7	0.0	0.3	0.4	0.7	0.0	-0.2	0.3	0.2
Osteoporosis (self-reported)	0.2	0.3	1.9	0.6	-0.1	-0.3	-0.1	-0.2	0.4	0.4	0.1	-0.0	1.4	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.8	0.5	0.8	1.7	0.9	0.4	0.4	0.4	0.4	0.2	0.5	0.4
Number of self-reported non-cancer illnesses	0.2	0.3	1.4	-0.4	-1.2	-0.7	-0.4	-0.4	-0.6	-0.3	-0.4	0.4	-0.1	-0.4
Guilty feelings	0.2	0.3	1.9	-0.2	1.0	1.4	0.1	-0.0	-0.1	0.2	-0.4	-0.7	-0.0	0.1
Mother’s age at death	0.2	0.2	0.8	0.5	0.5	0.9	0.7	0.1	0.4	-0.4	0.5	-0.3	-0.2	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.2	0.5	-0.8	-0.2	-0.1	-0.3	0.0	-0.6	0.2	0.0	1.1	-0.0
Arm fat-free mass (left)	0.2	1.2	2.9	-1.6	-0.4	-0.0	-0.6	-0.6	-1.4	0.0	-1.2	0.1	-1.7	-1.7
Unable to work because of sickness or disability	0.2	0.2	0.6	-0.3	-0.2	0.2	-0.2	-0.7	-0.8	-0.6	-0.7	-0.5	-0.3	-0.3
Heart disease (siblings)	0.2	0.2	0.4	-0.6	-0.5	-0.4	-0.6	-0.3	-0.5	0.0	-0.6	-0.1	-0.2	-0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.8	-0.8	-0.1	0.8	-0.5	-0.3	-0.4	-0.2	-0.6	-0.7	-0.3	-0.9
Reaction Time	0.1	0.1	0.4	0.3	0.3	-0.4	0.0	-0.4	0.6	0.1	0.0	-0.7	-0.2	0.3
Prostate Cancer	0.1	0.1	0.4	-0.3	0.4	0.1	0.0	0.4	0.3	0.2	0.2	-0.1	-0.6	0.1
Heel T-Score	0.1	1.0	3.8	-0.5	-0.7	0.2	-0.8	-0.7	-1.6	-1.9	-1.0	-1.2	0.3	-0.6
Waist Hip Ratio (WHR)	0.1	0.3	2.1	0.1	0.3	1.5	0.6	-0.2	-0.4	0.1	-0.2	0.1	0.1	0.4
Systolic Blood Pressure	0.1	0.4	1.0	0.5	0.0	1.0	0.7	0.8	0.1	0.1	0.6	0.9	0.2	0.6
Hair Pigment	0.1	2.9	7.4	0.8	2.3	2.3	0.8	2.1	1.6	2.7	0.9	0.9	1.4	1.3
Vitamin and mineral supplements	0.1	0.1	0.4	0.6	0.3	0.4	0.6	0.3	-0.0	-0.2	0.2	0.2	0.1	0.6
Leg fat-free mass (left)	0.1	0.5	0.9	-0.9	0.7	0.5	-0.2	0.1	-0.9	0.9	-1.0	0.3	-0.8	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.6	-0.6	-0.6	-0.4	-0.7	-0.4	-0.8	-0.7	-0.7	-0.5	-0.1	-0.6
Multivitamins +/- minerals	0.1	0.1	0.5	0.4	0.3	-0.1	-0.1	0.7	0.3	0.0	0.4	0.1	0.4	0.1
Medication: Levothyroxine sodium	0.1	0.2	0.8	-0.0	0.2	0.4	0.5	-0.3	-0.2	-0.4	0.1	-0.1	-0.9	-0.3
Sitting height	0.1	0.6	2.6	-0.5	1.0	1.6	0.2	0.2	0.2	1.6	-0.2	0.3	0.2	-0.2
High blood pressure (mother)	0.1	0.2	1.5	-0.0	-0.4	-1.2	-0.3	-0.4	-0.1	0.1	-0.2	0.1	0.1	-0.0
Leg predicted mass (left)	0.1	0.5	1.0	-0.9	0.8	0.6	-0.2	0.1	-0.9	1.0	-0.9	0.4	-0.7	-0.8
Had other major operations	0.1	0.1	0.2	-0.3	0.1	-0.3	-0.2	0.2	-0.5	-0.1	-0.3	0.1	-0.3	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.3	-0.3	-0.2	-0.5	-0.6	-0.0	-0.4	-0.4	-0.4	-0.3	0.4	-0.2
Medication: Ramipril	0.1	0.1	0.1	-0.4	-0.4	0.4	0.0	-0.2	-0.3	0.1	-0.2	0.3	-0.1	-0.3
Trunk fat-free mass	0.1	0.8	2.6	-1.4	0.3	0.7	-0.2	-0.0	-0.5	0.9	-0.7	0.4	-1.6	-1.3
Hip circumference	0.1	0.4	1.1	-0.8	0.4	0.1	-0.4	-0.1	-1.1	0.2	-1.0	0.0	-0.7	-0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	3.5	-0.3	0.5	1.9	0.3	-0.1	-0.2	0.0	-0.1	-0.4	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	3.9	-0.1	0.6	2.0	0.4	-0.1	0.2	0.2	0.0	-0.5	0.2	-0.0
Trunk predicted mass	0.1	0.8	2.7	-1.5	0.3	0.8	-0.3	-0.1	-0.6	0.8	-0.7	0.3	-1.6	-1.4
Standing height	0.1	0.6	2.3	-0.2	1.1	1.5	0.1	0.4	0.3	1.5	-0.2	0.1	0.7	0.1
Exposure to tobacco smoke at home	0.1	0.1	0.7	-0.2	0.1	0.0	-0.2	0.4	-0.2	-0.3	-0.0	-0.2	-0.9	0.0
Breastfed as a baby	0.1	0.2	0.6	0.1	0.6	0.6	0.2	-0.0	0.3	0.4	-0.0	-0.4	0.2	0.7
Tense / ‘highly strung’	0.1	0.2	0.7	-0.4	-0.5	0.3	-0.2	0.3	-0.2	-0.7	0.0	-0.2	-0.8	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.5	-0.4	-0.2	0.2	-0.2	-0.1	-0.5	-0.5	-0.3	-0.3	-0.7	-0.2
Headache pain in last month	0.1	0.3	2.0	-0.4	0.2	0.5	0.2	-0.0	-0.1	-0.1	-0.1	-0.1	-1.4	-0.4
Exposure to tobacco smoke outside home	0.1	0.1	0.3	0.0	0.1	0.5	0.1	0.2	0.3	0.4	0.2	0.2	0.5	-0.2
Eye problems/disorders: None of the above	0.1	0.1	0.2	0.4	0.2	0.5	0.4	0.3	0.3	0.3	0.4	0.4	0.5	0.2
Arm predicted mass (right)	0.1	0.6	1.5	-1.1	-0.2	-0.1	-0.4	-0.4	-1.1	0.4	-0.9	0.5	-0.9	-1.2
Chest pain or discomfort	0.1	0.1	0.6	-0.2	0.0	0.2	-0.0	0.0	0.3	0.8	0.0	0.2	-0.2	0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.4	0.1	0.2	0.6	0.3	0.6	0.5	0.5	0.3	0.4	0.1	0.3
Supplements: Vitamin C	0.1	0.1	0.2	-0.1	-0.4	-0.3	-0.2	0.2	-0.0	0.3	0.1	0.5	0.5	0.0
Whole body fat-free mass	0.1	0.7	1.5	-1.2	0.5	0.6	-0.2	0.1	-0.8	0.9	-0.8	0.4	-1.2	-1.1
Leg fat-free mass (right)	0.1	0.4	1.0	-0.7	0.7	0.5	-0.2	0.1	-0.7	1.0	-0.8	0.4	-0.3	-0.7
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.1	0.2	-0.3	-0.1	-0.4	-0.2	-0.3	-0.4	-0.5	0.2	-0.3
Ever had bowel cancer screening	0.1	0.2	0.3	0.5	0.3	-0.4	0.2	0.5	0.4	-0.6	0.5	-0.2	-0.3	0.5
Friendships satisfaction	0.1	0.1	0.2	-0.3	-0.5	-0.3	-0.3	0.1	0.3	-0.3	0.3	-0.2	-0.4	-0.2
Breast cancer (self-reported)	0.1	0.1	0.4	0.4	0.6	0.2	0.2	0.1	0.3	0.4	0.1	-0.0	0.3	0.1
Whole body water mass	0.1	0.8	1.9	-1.4	0.3	0.5	-0.4	-0.2	-1.0	0.7	-1.0	0.2	-1.3	-1.3
Leg predicted mass (right)	0.1	0.4	1.0	-0.7	0.7	0.5	-0.1	0.1	-0.7	1.0	-0.8	0.4	-0.3	-0.7
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.5	-0.4	0.1	0.4	0.2	-0.1	0.3	0.3	0.1	-0.0	-0.7	-0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.4	0.5	0.4	0.3	0.4	0.1	-0.3	0.2	-0.1	0.0	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.6	0.0	-0.5	-0.8	-0.1	-0.4	0.1	-0.7	0.1	-0.3	-0.4	-0.4
Medication: Paracetamol	0.1	0.1	0.9	-0.1	0.5	0.9	0.3	0.3	-0.1	0.0	-0.1	-0.1	-0.4	0.0
Ever smoked	0.1	0.1	0.6	0.1	-0.1	0.1	0.4	0.2	0.1	-0.3	0.3	0.3	-0.8	0.3
Basal metabolic rate	0.1	0.8	2.3	-1.4	0.4	0.5	-0.3	-0.0	-1.0	0.7	-1.0	0.3	-1.5	-1.3
Number of operations (self-reported)	0.1	0.1	0.3	-0.3	0.6	0.5	0.0	0.4	-0.2	0.3	-0.1	0.1	-0.3	-0.1
Average weekly beer plus cider intake	0.1	0.1	0.7	-0.1	-0.0	-0.3	-0.2	0.2	0.0	0.8	-0.0	0.5	0.5	0.1
Risk taking	0.1	0.2	0.6	-0.3	-0.5	-0.6	0.0	-0.5	0.6	0.8	0.4	0.4	0.0	-0.1
Diastolic blood pressure, automated reading	0.1	0.3	1.2	-1.1	-0.3	0.7	-0.5	0.1	-0.0	0.4	-0.3	-0.1	-0.9	-0.9
Impedance of whole body	0.1	0.7	3.4	1.2	0.4	0.6	0.3	0.2	0.6	-0.1	0.5	-0.5	1.8	1.3
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.2	1.0	0.1	0.1	-0.3	0.2	0.7	-0.1	0.5	0.2	1.0	-0.3	0.0
Lung FVC	0.0	0.2	1.0	-0.4	-0.0	0.8	0.3	-0.6	0.5	1.0	0.1	0.2	0.1	-0.4
Systolic blood pressure, automated reading	0.0	0.1	0.5	-0.0	0.1	0.7	0.2	0.5	0.1	0.3	0.2	0.5	-0.1	0.0
Impedance of leg (right)	0.0	0.1	0.2	-0.0	-0.3	0.2	-0.0	-0.1	0.1	-0.5	0.2	-0.4	-0.3	0.2
Impedance of leg (left)	0.0	0.1	0.2	0.3	-0.3	0.1	0.2	0.0	0.4	-0.5	0.5	-0.2	0.1	0.4
Comparative height size at age 10	0.0	0.3	1.2	-0.3	0.8	1.1	0.1	0.3	-0.3	0.5	-0.5	-0.1	-0.3	-0.2
Medication: Blood pressure	0.0	0.0	0.1	-0.2	-0.0	0.1	-0.1	0.3	-0.1	-0.1	-0.0	0.1	-0.3	-0.1

Hub : Genes

C7orf28A

Models

Trait associations