TWAS hub - C7orf28B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.1570	0.0640	5.9e-12	0.159	0.140	0.162	NA	0.159	2.2e-13	6.7e-12	1.2e-13	NA	2.2e-13
2	TCGA	Breast Invasive Carcinoma	0.1154	0.0532	0.0e+00	0.105	0.092	0.101	NA	0.102	9.9e-21	2.9e-18	6.2e-20	NA	3.5e-20
3	TCGA	Colon Adenocarcinoma	0.0770	0.0390	1.4e-04	0.049	0.074	0.072	NA	0.056	8.1e-04	4.6e-05	5.9e-05	NA	3.4e-04
4	TCGA	Glioblastoma Multiforme	0.2210	0.0950	5.7e-05	0.140	0.082	0.126	NA	0.137	5.1e-05	1.8e-03	1.2e-04	NA	5.9e-05
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.1454	0.0596	9.0e-14	0.132	0.123	0.129	NA	0.132	1.2e-14	1.2e-13	2.8e-14	NA	1.3e-14
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0803	0.0362	5.0e-09	0.083	0.072	0.079	NA	0.076	1.4e-09	1.5e-08	3.4e-09	NA	6.2e-09
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0910	0.0460	2.2e-04	0.081	0.056	0.066	NA	0.065	2.1e-05	3.8e-04	1.2e-04	NA	1.3e-04
8	TCGA	Brain Lower Grade Glioma	0.0993	0.0431	3.7e-11	0.116	0.087	0.109	NA	0.113	4.7e-13	4.0e-10	2.1e-12	NA	8.7e-13
9	TCGA	Lung Adenocarcinoma	0.0985	0.0421	6.8e-12	0.115	0.104	0.107	NA	0.116	2.2e-13	4.1e-12	1.7e-12	NA	2.1e-13
10	TCGA	Lung Squamous Cell Carcinoma	0.0764	0.0358	2.3e-08	0.087	0.047	0.055	NA	0.079	4.0e-10	3.9e-06	7.0e-07	NA	2.6e-09
11	TCGA	Ovarian Serous Cystadenocarcinoma	0.0820	0.0390	1.3e-05	0.098	0.084	0.094	NA	0.091	3.5e-07	2.7e-06	6.2e-07	NA	9.8e-07
12	TCGA	Pancreatic Adenocarcinoma	0.0810	0.0470	8.1e-03	0.056	0.026	0.028	NA	0.036	2.3e-03	2.9e-02	2.4e-02	NA	1.3e-02
13	TCGA	Pheochromocytoma and Paraganglioma	0.2390	0.0930	3.9e-08	0.232	0.180	0.216	NA	0.220	1.2e-09	1.2e-07	5.1e-09	NA	3.4e-09
14	TCGA	Prostate Adenocarcinoma	0.1020	0.0436	2.3e-11	0.121	0.103	0.114	NA	0.118	1.2e-12	6.4e-11	6.2e-12	NA	2.4e-12
15	TCGA	Soft Tissue Sarcoma	0.1370	0.0580	2.2e-06	0.112	0.089	0.083	NA	0.096	3.6e-07	5.8e-06	1.2e-05	NA	2.5e-06
16	TCGA	Stomach Adenocarcinoma	0.0900	0.0470	6.1e-06	0.067	0.069	0.067	NA	0.060	1.3e-05	1.1e-05	1.4e-05	NA	3.9e-05
17	TCGA	Thyroid Carcinoma	0.1240	0.0530	5.7e-12	0.144	0.117	0.138	NA	0.142	6.3e-14	2.0e-11	2.6e-13	NA	1.1e-13
18	TCGA	Uterine Corpus Endometrial Carcinoma	0.1590	0.0790	1.3e-03	0.111	0.135	0.039	NA	0.095	5.3e-04	1.4e-04	3.0e-02	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Other serious medical condition/disability diagnosed by doctor	7.9	10.3	12.7	-3.1	-3.4	-3.2	-1.0	-3.3	-3.4	-3.0	-3.5	-3.4	-3.5	-3.2	-3.2	-3.6	-3.4	-3.4	-3.1	-3.5	-2.8
Neck or shoulder pain in last month	5.5	7.9	9.2	-2.8	-2.8	-2.9	-1.9	-2.8	-2.9	-2.8	-2.8	-2.9	-2.8	-2.8	-2.8	-2.9	-2.8	-2.8	-3.0	-2.8	-3.0
Respiratory disease	4.9	10.9	14.1	-3.2	-3.7	-2.8	-0.6	-3.6	-3.3	-3.1	-3.8	-3.5	-3.8	-3.4	-3.4	-3.7	-3.6	-3.7	-2.8	-3.8	-2.4
Knee pain experienced in last month	4.5	7.0	8.8	-2.6	-2.6	-1.9	-2.5	-2.8	-2.7	-2.8	-2.7	-2.8	-2.7	-3.0	-2.9	-2.7	-2.5	-2.6	-2.6	-2.7	-2.5
Blood White Count	4.4	32.6	49.8	-6.4	-5.4	-6.0	-5.4	-5.5	-6.2	-6.0	-5.2	-5.4	-5.2	-5.2	-5.2	-5.5	-5.9	-5.5	-6.2	-5.2	-7.1
Medication: Seretide 50 evohaler	4.4	5.1	6.7	-2.2	-2.3	-2.6	-1.0	-2.2	-2.4	-2.1	-2.3	-2.3	-2.3	-2.1	-2.1	-2.4	-2.3	-2.3	-2.5	-2.3	-2.3
Length of working week for main job	4.1	4.5	11.8	-2.5	-1.9	-0.8	-3.4	-2.1	-2.2	-2.6	-1.8	-2.0	-1.8	-2.2	-2.2	-1.8	-2.0	-1.9	-1.6	-1.8	-2.3
Wheeze or whistling in the chest in last year	4.1	7.3	9.3	-2.7	-2.8	-3.0	-1.0	-2.7	-2.9	-2.5	-2.8	-2.8	-2.8	-2.5	-2.6	-2.9	-2.8	-2.8	-2.7	-2.8	-2.7
Asthma (self-reported)	3.6	7.1	9.8	-2.3	-3.0	-3.1	0.5	-2.7	-2.6	-2.1	-3.0	-2.8	-3.0	-2.5	-2.5	-3.0	-2.9	-3.0	-2.8	-3.0	-2.0
Asthma	3.4	6.7	8.7	-2.2	-2.9	-2.9	0.6	-2.7	-2.5	-2.0	-2.9	-2.7	-2.9	-2.4	-2.5	-3.0	-2.8	-2.9	-2.6	-2.9	-1.9
Illnesses of father: High blood pressure	3.4	4.2	7.5	1.9	2.0	2.3	1.3	2.0	1.9	2.0	2.0	2.0	2.0	2.0	2.0	2.0	2.0	2.0	2.7	2.0	2.3
Whole body fat mass	3.2	13.2	19.0	-3.6	-3.6	-4.1	-2.4	-3.6	-3.7	-3.6	-3.5	-3.6	-3.5	-3.5	-3.5	-3.6	-3.7	-3.6	-4.4	-3.5	-4.1
Prostate Cancer	3.0	4.2	5.2	1.9	2.2	1.7	1.1	2.2	2.0	2.0	2.2	2.2	2.2	2.3	2.3	2.2	2.0	2.1	2.1	2.2	1.7
Alcohol drinker status: Previous	3.0	3.4	4.1	-1.9	-1.9	-1.7	-1.3	-1.9	-2.0	-1.9	-1.9	-1.9	-1.9	-1.9	-1.9	-2.0	-1.9	-1.9	-1.7	-1.9	-1.9
Arm fat mass (right)	2.9	12.0	15.9	-3.5	-3.4	-3.6	-2.7	-3.5	-3.5	-3.5	-3.4	-3.4	-3.4	-3.4	-3.4	-3.4	-3.5	-3.4	-4.0	-3.4	-3.9
Diverticular disease/diverticulitis (self-reported)	2.8	3.3	4.1	-2.0	-1.8	-2.0	-1.2	-1.8	-1.9	-1.8	-1.8	-1.8	-1.8	-1.6	-1.7	-1.8	-2.0	-1.9	-2.0	-1.8	-2.0
Arm fat percentage (right)	2.7	10.7	15.7	-3.3	-3.2	-3.9	-1.8	-3.2	-3.3	-3.1	-3.2	-3.2	-3.2	-3.0	-3.0	-3.3	-3.4	-3.3	-4.0	-3.2	-3.7
Happiness	2.7	3.3	6.0	2.2	1.8	2.1	1.3	1.8	1.6	1.9	1.7	1.5	1.7	1.5	1.5	1.5	2.1	1.9	2.4	1.7	2.2
Body fat percentage	2.7	10.5	19.1	-3.1	-3.2	-4.4	-1.0	-3.1	-3.2	-2.9	-3.2	-3.1	-3.2	-2.8	-2.9	-3.3	-3.3	-3.3	-4.2	-3.2	-3.6
Myopia	2.7	3.9	5.1	2.2	2.0	0.7	2.2	2.1	2.1	2.3	2.0	2.1	2.0	2.2	2.2	2.0	2.1	2.0	1.2	2.0	1.6
Trunk fat percentage	2.5	9.9	18.6	-3.0	-3.1	-4.3	-0.9	-3.0	-3.1	-2.8	-3.1	-2.9	-3.1	-2.7	-2.8	-3.1	-3.3	-3.2	-4.2	-3.1	-3.5
Trunk fat mass	2.5	10.6	16.5	-3.2	-3.2	-3.8	-1.8	-3.2	-3.2	-3.1	-3.2	-3.1	-3.2	-3.0	-3.1	-3.2	-3.3	-3.3	-4.1	-3.2	-3.6
Hip circumference	2.5	10.6	15.8	-3.3	-3.2	-3.5	-2.4	-3.2	-3.2	-3.3	-3.1	-3.1	-3.1	-3.1	-3.1	-3.1	-3.3	-3.2	-4.0	-3.1	-3.7
Leg fat mass (right)	2.5	9.8	12.4	-3.2	-3.1	-3.2	-2.5	-3.1	-3.2	-3.2	-3.0	-3.1	-3.0	-3.1	-3.1	-3.1	-3.2	-3.1	-3.5	-3.0	-3.5
Arm fat mass (left)	2.5	10.4	13.3	-3.3	-3.1	-3.3	-2.6	-3.2	-3.3	-3.3	-3.1	-3.2	-3.1	-3.2	-3.2	-3.2	-3.3	-3.2	-3.6	-3.1	-3.6
Hearing aid user	2.5	2.8	4.0	1.8	1.6	1.9	1.3	1.6	1.9	1.7	1.6	1.7	1.6	1.6	1.6	1.7	1.7	1.6	1.8	1.6	2.0
Leg fat mass (left)	2.5	9.8	13.1	-3.2	-3.1	-3.4	-2.3	-3.1	-3.2	-3.1	-3.0	-3.1	-3.0	-3.0	-3.0	-3.1	-3.1	-3.1	-3.6	-3.0	-3.5
Illnesses of siblings	2.3	3.2	4.1	1.8	1.8	1.6	1.6	1.8	1.8	1.9	1.8	1.8	1.8	1.9	1.9	1.7	1.8	1.8	2.0	1.8	1.9
Arm fat percentage (left)	2.3	9.3	14.1	-3.1	-3.0	-3.7	-1.8	-3.0	-3.1	-2.9	-3.0	-2.9	-3.0	-2.8	-2.8	-3.0	-3.1	-3.1	-3.8	-3.0	-3.5
Headache pain in last month	2.2	3.8	8.2	-2.0	-1.6	-2.7	-1.9	-1.7	-2.2	-1.9	-1.6	-1.8	-1.6	-1.6	-1.6	-1.8	-1.8	-1.6	-2.4	-1.6	-2.9
Hypothyroidism (self reported)	2.1	4.9	6.1	-2.5	-2.3	-1.9	-1.4	-2.3	-2.3	-2.3	-2.3	-2.2	-2.3	-2.1	-2.2	-2.3	-2.5	-2.4	-2.0	-2.3	-2.1
Medication: Metformin	2.1	3.0	4.4	1.7	2.0	0.3	0.6	2.0	1.5	1.7	2.1	1.9	2.1	2.0	2.0	1.9	1.9	2.0	0.8	2.1	0.6
Chest pain or discomfort	2.1	3.1	7.7	-1.6	-1.6	-2.8	-0.7	-1.6	-1.9	-1.5	-1.6	-1.6	-1.6	-1.4	-1.4	-1.8	-1.7	-1.6	-2.4	-1.6	-2.3
Commuting to job workplace: Public transport	2.1	2.5	3.1	1.7	1.7	0.7	0.9	1.7	1.6	1.7	1.7	1.7	1.7	1.7	1.7	1.7	1.8	1.8	0.9	1.7	1.1
Type 2 Diabetes (T2D) (2018)	2.0	3.8	5.4	1.9	2.3	0.7	0.5	2.2	1.9	1.9	2.3	2.2	2.3	2.2	2.2	2.2	2.2	2.3	1.0	2.3	0.8
Time employed in main current job	2.0	2.4	6.8	-1.0	-1.4	-2.6	-0.1	-1.4	-1.4	-1.1	-1.5	-1.5	-1.5	-1.4	-1.4	-1.6	-1.3	-1.4	-2.5	-1.5	-1.7
Medication: Lansoprazole	2.0	2.3	2.9	-1.7	-1.5	-0.7	-1.6	-1.6	-1.6	-1.7	-1.5	-1.6	-1.5	-1.6	-1.6	-1.5	-1.6	-1.5	-0.9	-1.5	-1.3
Basal cell carcinoma (self-reported)	2.0	2.4	3.2	-1.6	-1.6	-0.5	-1.5	-1.7	-1.6	-1.7	-1.6	-1.7	-1.6	-1.8	-1.8	-1.6	-1.6	-1.6	-0.9	-1.6	-1.1
Allergy	1.9	4.5	5.8	1.8	2.4	2.3	-0.3	2.2	2.0	1.7	2.4	2.2	2.4	2.1	2.1	2.4	2.2	2.4	2.2	2.4	1.5
Weight	1.9	9.3	10.8	-3.1	-3.0	-2.5	-3.0	-3.1	-3.1	-3.3	-3.0	-3.1	-3.0	-3.2	-3.2	-3.0	-3.0	-3.0	-3.2	-3.0	-3.3
Leg fat percentage (right)	1.9	6.8	10.4	-2.5	-2.6	-3.2	-1.1	-2.6	-2.7	-2.4	-2.6	-2.6	-2.6	-2.4	-2.4	-2.7	-2.7	-2.7	-3.1	-2.6	-2.8
Hearing difficulty/problems: Yes	1.8	2.7	4.1	-1.6	-1.6	-2.0	-1.0	-1.6	-1.7	-1.6	-1.6	-1.6	-1.6	-1.5	-1.5	-1.6	-1.7	-1.6	-2.0	-1.6	-1.9
Guilty feelings	1.8	2.7	3.5	-1.5	-1.8	-1.0	-0.8	-1.8	-1.7	-1.6	-1.9	-1.9	-1.9	-1.9	-1.9	-1.8	-1.7	-1.8	-1.2	-1.9	-1.1
Leg fat percentage (left)	1.8	6.6	12.2	-2.4	-2.5	-3.5	-0.8	-2.5	-2.6	-2.3	-2.5	-2.5	-2.5	-2.3	-2.3	-2.6	-2.6	-2.6	-3.3	-2.5	-2.9
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	3.8	-1.3	-1.9	-1.8	0.7	-1.7	-1.6	-1.2	-1.9	-1.8	-1.9	-1.6	-1.6	-2.0	-1.8	-1.9	-1.5	-1.9	-0.9
Birth weight of first child	1.7	3.1	3.8	-1.7	-1.7	-1.7	-1.6	-1.7	-1.9	-1.8	-1.7	-1.9	-1.7	-1.8	-1.8	-1.8	-1.7	-1.7	-1.8	-1.7	-1.9
Hypothyroidism/myxoedema (self-reported)	1.7	3.4	4.0	-1.9	-1.9	-1.6	-1.1	-1.9	-1.8	-1.9	-1.9	-1.8	-1.9	-1.8	-1.8	-1.9	-2.0	-2.0	-1.8	-1.9	-1.8
Mouth/teeth dental problems: Loose teeth	1.7	2.0	6.6	1.1	1.4	2.6	-0.6	1.2	1.3	0.9	1.4	1.2	1.4	1.0	1.0	1.4	1.4	1.4	2.1	1.4	1.6
Osteoporosis (self-reported)	1.7	2.1	2.6	-1.5	-1.6	-0.5	-1.0	-1.6	-1.4	-1.5	-1.6	-1.5	-1.6	-1.6	-1.6	-1.5	-1.6	-1.6	-0.9	-1.6	-1.0
Ever had prostate specific antigen (PSA) test	1.7	2.0	3.0	-1.1	-1.6	-0.5	-0.3	-1.6	-1.4	-1.3	-1.7	-1.7	-1.7	-1.7	-1.7	-1.7	-1.4	-1.6	-0.7	-1.7	-0.5
Age at last live birth	1.6	2.4	3.1	1.6	1.5	1.7	1.0	1.5	1.7	1.5	1.5	1.6	1.5	1.5	1.5	1.6	1.6	1.5	1.6	1.5	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	6.1	-0.8	-1.4	-2.5	0.9	-1.2	-1.5	-0.8	-1.4	-1.5	-1.4	-1.1	-1.2	-1.7	-1.3	-1.4	-1.6	-1.4	-1.3
Body mass index (BMI)	1.5	6.5	7.8	-2.7	-2.5	-2.1	-2.6	-2.6	-2.7	-2.8	-2.5	-2.6	-2.5	-2.6	-2.6	-2.5	-2.5	-2.5	-2.6	-2.5	-2.8
Emphysema/chronic bronchitis	1.5	1.7	2.3	-1.4	-1.4	-1.5	-0.1	-1.4	-1.3	-1.2	-1.4	-1.3	-1.4	-1.2	-1.2	-1.4	-1.5	-1.5	-1.4	-1.4	-1.2
Long-standing illness, disability or infirmity	1.5	2.3	3.4	-1.5	-1.6	-1.8	-0.4	-1.5	-1.8	-1.4	-1.6	-1.6	-1.6	-1.4	-1.4	-1.7	-1.6	-1.6	-1.4	-1.6	-1.5
BMI	1.4	8.4	15.4	-3.1	-2.6	-2.1	-3.9	-2.8	-3.1	-3.3	-2.5	-2.9	-2.5	-3.0	-3.0	-2.6	-2.7	-2.6	-2.8	-2.5	-3.4
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.2	1.2	1.4	0.5	1.1	1.4	1.2	1.4	1.4	1.4	1.4	1.5	1.5	1.3	1.3	1.3	0.9	1.4	0.9
Exposure to tobacco smoke at home	1.4	1.6	2.0	-1.2	-1.3	-0.6	-1.2	-1.3	-1.4	-1.3	-1.3	-1.4	-1.3	-1.4	-1.4	-1.3	-1.2	-1.3	-0.8	-1.3	-1.0
Age at first live birth	1.4	2.4	3.6	1.6	1.5	1.9	0.9	1.5	1.8	1.5	1.5	1.6	1.5	1.4	1.4	1.6	1.6	1.5	1.7	1.5	1.8
Waist Hip Ratio (WHR)	1.3	6.1	7.3	2.6	2.7	1.1	1.9	2.7	2.6	2.6	2.7	2.7	2.7	2.7	2.7	2.6	2.6	2.6	1.5	2.7	1.8
Multivitamins +/- minerals	1.3	1.7	2.2	1.3	1.4	0.8	1.1	1.4	1.0	1.4	1.4	1.3	1.4	1.5	1.5	1.2	1.3	1.3	1.4	1.4	1.1
Blood clot in the leg (DVT)	1.3	1.7	2.6	-1.2	-1.5	-0.4	-0.8	-1.5	-1.3	-1.4	-1.5	-1.5	-1.5	-1.6	-1.6	-1.5	-1.3	-1.4	-0.7	-1.5	-0.7
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.1	-1.0	-1.4	-1.3	0.3	-1.3	-1.1	-1.0	-1.4	-1.3	-1.4	-1.2	-1.2	-1.4	-1.3	-1.4	-1.3	-1.4	-0.8
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.0	1.1	1.2	2.0	0.2	1.1	1.2	1.0	1.1	1.1	1.1	1.0	1.0	1.2	1.2	1.2	1.8	1.1	1.6
Mineral and other dietary supplements	1.3	1.8	2.6	1.3	1.5	1.0	0.3	1.4	1.5	1.2	1.5	1.5	1.5	1.3	1.4	1.6	1.5	1.5	0.7	1.5	0.9
Osteoarthritis (self-reported)	1.3	1.7	2.6	-0.9	-1.5	-0.7	0.4	-1.4	-1.2	-1.0	-1.6	-1.5	-1.6	-1.4	-1.5	-1.6	-1.3	-1.5	-0.6	-1.6	-0.3
Heart attack/myocardial infarction (self-reported)	1.3	1.7	2.2	1.2	1.5	0.8	0.6	1.4	1.2	1.3	1.5	1.4	1.5	1.5	1.5	1.4	1.4	1.4	1.1	1.5	0.9
Blood Red Count	1.2	11.2	17.0	-3.4	-3.3	-4.1	-2.0	-3.2	-3.4	-3.2	-3.2	-3.2	-3.2	-3.0	-3.0	-3.3	-3.4	-3.3	-4.1	-3.2	-4.0
Lung FVC	1.2	6.1	8.4	2.5	2.5	2.7	1.3	2.5	2.4	2.4	2.5	2.4	2.5	2.4	2.4	2.5	2.6	2.6	2.9	2.5	2.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	1.6	-1.1	-1.1	-1.0	-1.2	-1.1	-1.2	-1.2	-1.1	-1.2	-1.1	-1.2	-1.2	-1.1	-1.1	-1.1	-1.2	-1.1	-1.3
Average weekly fortified wine intake	1.2	1.4	2.3	-1.5	-1.3	-0.6	-0.8	-1.3	-1.3	-1.3	-1.2	-1.1	-1.2	-1.1	-1.1	-1.2	-1.5	-1.3	-0.7	-1.2	-1.0
Relative age voice broke	1.2	1.8	4.1	-1.5	-1.1	-1.9	-1.4	-1.2	-1.5	-1.4	-1.0	-1.1	-1.0	-1.1	-1.1	-1.2	-1.3	-1.2	-1.9	-1.0	-2.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.1	-1.2	-1.3	0.1	-0.7	-1.3	-1.4	-1.2	-1.4	-1.5	-1.4	-1.4	-1.4	-1.4	-1.2	-1.3	0.0	-1.4	-0.3
Medication: Cholesterol lowering	1.2	1.8	3.4	1.6	1.3	-0.1	1.8	1.4	1.6	1.6	1.3	1.5	1.3	1.5	1.5	1.4	1.4	1.3	0.1	1.3	1.0
Diastolic blood pressure, automated reading	1.2	3.7	5.4	-1.7	-2.3	-1.3	0.1	-2.1	-1.8	-1.7	-2.3	-2.1	-2.3	-2.0	-2.1	-2.2	-2.1	-2.3	-1.4	-2.3	-1.0
Leg fat-free mass (left)	1.1	5.9	13.4	-2.6	-2.2	-1.0	-3.7	-2.4	-2.4	-2.9	-2.2	-2.4	-2.2	-2.7	-2.7	-2.1	-2.2	-2.2	-2.0	-2.2	-2.5
Leg predicted mass (left)	1.1	5.8	13.1	-2.6	-2.2	-0.9	-3.6	-2.4	-2.4	-2.9	-2.2	-2.4	-2.2	-2.7	-2.7	-2.1	-2.2	-2.2	-1.9	-2.2	-2.4
Waist circumference	1.1	4.0	6.9	-2.0	-1.9	-2.4	-1.6	-1.9	-2.0	-2.0	-1.9	-1.9	-1.9	-1.9	-1.9	-1.9	-1.9	-1.9	-2.6	-1.9	-2.4
Hearing difficulty/problems with background noise	1.1	1.7	5.1	-1.0	-1.3	-2.3	0.5	-1.2	-1.3	-0.9	-1.3	-1.2	-1.3	-0.9	-1.0	-1.4	-1.3	-1.3	-1.8	-1.3	-1.4
Illnesses of father: Heart disease	1.1	1.5	1.8	-1.3	-1.3	-0.6	-0.9	-1.3	-1.2	-1.3	-1.3	-1.3	-1.3	-1.4	-1.4	-1.3	-1.3	-1.3	-0.9	-1.3	-0.9
Leg fat-free mass (right)	1.1	5.6	11.8	-2.6	-2.2	-1.1	-3.4	-2.4	-2.3	-2.8	-2.2	-2.4	-2.2	-2.6	-2.6	-2.1	-2.2	-2.2	-2.1	-2.2	-2.5
Leg predicted mass (right)	1.1	5.7	12.1	-2.6	-2.2	-1.0	-3.5	-2.4	-2.4	-2.8	-2.2	-2.4	-2.2	-2.7	-2.6	-2.1	-2.2	-2.2	-2.0	-2.2	-2.5
Supplements: Fish oil (including cod liver oil)	1.1	1.4	1.9	-1.1	-1.3	-1.4	-0.1	-1.2	-1.3	-1.0	-1.3	-1.3	-1.3	-1.1	-1.1	-1.4	-1.3	-1.3	-1.1	-1.3	-1.1
Basal metabolic rate	1.1	5.9	11.8	-2.6	-2.2	-1.2	-3.4	-2.5	-2.5	-2.8	-2.2	-2.5	-2.2	-2.7	-2.7	-2.2	-2.2	-2.2	-2.1	-2.2	-2.6
Average weekly beer plus cider intake	1.1	1.6	3.1	1.3	1.2	-0.1	1.8	1.3	1.3	1.5	1.2	1.4	1.2	1.5	1.5	1.2	1.2	1.2	0.3	1.2	0.8
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.0	-1.1	-1.4	-0.2	-0.5	-1.3	-1.1	-1.2	-1.4	-1.4	-1.4	-1.4	-1.4	-1.3	-1.2	-1.3	-0.5	-1.4	-0.5
Systolic blood pressure, automated reading	1.0	2.9	4.3	-1.6	-1.9	-2.1	0.3	-1.7	-1.6	-1.4	-1.9	-1.6	-1.9	-1.5	-1.5	-1.8	-1.9	-1.9	-1.9	-1.9	-1.4
Medication for hormone replacement therapy	1.0	1.2	1.7	0.9	1.2	1.1	0.0	1.1	0.9	0.9	1.2	1.1	1.2	1.1	1.1	1.1	1.1	1.2	1.3	1.2	0.8
Maternal smoking around birth	1.0	1.5	4.5	-1.4	-1.1	-0.2	-2.1	-1.2	-1.3	-1.5	-1.1	-1.2	-1.1	-1.3	-1.3	-1.1	-1.1	-1.1	-0.7	-1.1	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.3	1.0	1.2	1.5	-0.4	1.1	0.9	0.9	1.2	1.0	1.2	0.9	1.0	1.1	1.3	1.3	1.5	1.2	1.0
Cholesterol lowering medication	1.0	1.5	7.0	-1.1	-1.0	-2.6	0.2	-0.9	-1.2	-0.8	-0.9	-0.9	-0.9	-0.5	-0.6	-1.1	-1.2	-1.1	-2.0	-0.9	-1.8
Pain experienced in last month	1.0	1.6	2.1	1.2	1.2	1.2	1.2	1.3	1.4	1.3	1.2	1.4	1.2	1.4	1.4	1.4	1.1	1.2	1.2	1.2	1.4
Crohns Disease (2017)	0.9	2.0	2.6	-1.4	-1.4	-0.8	-1.5	-1.5	-1.5	-1.5	-1.4	-1.5	-1.4	-1.6	-1.6	-1.4	-1.3	-1.4	-1.1	-1.4	-1.3
Relative age of first facial hair	0.9	1.9	4.6	-1.6	-1.1	-1.3	-2.1	-1.2	-1.5	-1.6	-1.0	-1.2	-1.0	-1.2	-1.2	-1.1	-1.2	-1.1	-1.5	-1.0	-2.0
Townsend deprivation index at recruitment	0.9	1.3	2.0	1.0	1.2	1.0	0.6	1.2	1.0	1.1	1.2	1.2	1.2	1.3	1.3	1.2	1.1	1.2	1.4	1.2	0.9
Age when periods started (menarche)	0.9	2.1	3.8	-1.4	-1.4	-1.7	-1.1	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-2.0	-1.4	-1.7
Heart attack	0.9	1.2	1.5	1.0	1.2	0.7	0.5	1.2	1.0	1.1	1.2	1.2	1.2	1.2	1.2	1.2	1.1	1.2	1.0	1.2	0.7
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.5	-1.1	-1.0	-0.2	-1.2	-1.1	-1.1	-1.2	-1.1	-1.1	-1.1	-1.2	-1.2	-1.0	-1.0	-1.0	-0.5	-1.1	-0.7
Illnesses of siblings: Diabetes	0.9	1.1	1.9	-1.1	-1.0	-0.6	-1.4	-1.1	-1.1	-1.2	-1.0	-1.1	-1.0	-1.2	-1.1	-1.0	-1.0	-1.0	-1.0	-1.0	-1.1
Whole body fat-free mass	0.9	4.9	12.0	-2.3	-2.0	-0.9	-3.5	-2.2	-2.2	-2.6	-2.0	-2.2	-2.0	-2.5	-2.5	-1.9	-2.0	-1.9	-1.8	-2.0	-2.3
Whole body water mass	0.9	5.3	12.4	-2.4	-2.1	-0.9	-3.5	-2.3	-2.3	-2.7	-2.1	-2.4	-2.1	-2.6	-2.6	-2.1	-2.1	-2.1	-1.9	-2.1	-2.3
Arm fat-free mass (left)	0.9	4.6	10.4	-2.3	-2.0	-0.8	-3.2	-2.2	-2.2	-2.5	-2.0	-2.2	-2.0	-2.5	-2.4	-2.0	-1.9	-1.9	-1.6	-2.0	-2.1
Supplements: Glucosamine	0.8	1.0	1.6	-0.9	-1.2	0.0	-0.5	-1.1	-1.1	-1.0	-1.2	-1.2	-1.2	-1.2	-1.2	-1.2	-1.0	-1.1	-0.0	-1.2	-0.2
Number of incorrect matches in round	0.8	1.3	6.0	1.3	0.9	-1.3	2.4	1.1	1.1	1.5	0.9	1.1	0.9	1.3	1.3	0.8	0.9	0.9	-0.5	0.9	0.4
Neuroticism score	0.8	1.7	2.9	-0.9	-1.5	-1.5	0.8	-1.3	-1.4	-0.8	-1.5	-1.5	-1.5	-1.2	-1.2	-1.7	-1.3	-1.4	-0.8	-1.5	-0.6
Ever highly irritable/argumentative for 2 days	0.8	0.9	1.6	-0.7	-0.9	-1.3	-0.2	-0.9	-1.1	-0.8	-1.0	-1.1	-1.0	-0.9	-0.9	-1.1	-0.8	-0.9	-1.1	-1.0	-1.0
Medication: Omeprazole	0.8	1.0	1.5	-0.8	-1.2	-0.9	0.4	-1.1	-1.0	-0.8	-1.2	-1.1	-1.2	-1.0	-1.0	-1.2	-1.1	-1.2	-0.8	-1.2	-0.4
Family relationship satisfaction	0.8	1.0	1.2	1.1	1.1	0.7	0.6	1.1	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.1	1.1	0.9	1.0	0.9
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.5	1.0	0.9	1.1	0.9	0.9	1.1	1.0	0.9	1.0	0.9	0.9	0.9	1.0	0.9	0.9	1.0	0.9	1.2
Diabetes diagnosed by doctor	0.8	1.3	2.1	1.2	1.3	-0.6	1.1	1.3	0.9	1.3	1.3	1.2	1.3	1.5	1.4	1.1	1.2	1.3	0.1	1.3	0.2
High cholesterol (Self-reported)	0.8	1.4	2.4	1.3	1.2	-0.7	1.5	1.3	1.2	1.4	1.2	1.2	1.2	1.4	1.4	1.1	1.2	1.1	-0.2	1.2	0.4
Irritability	0.8	1.4	2.2	-0.7	-1.4	-1.3	1.1	-1.2	-1.1	-0.7	-1.4	-1.3	-1.4	-1.1	-1.1	-1.5	-1.2	-1.4	-1.0	-1.4	-0.4
Arm predicted mass (left)	0.8	4.2	9.4	-2.1	-1.9	-0.9	-3.1	-2.0	-2.1	-2.4	-1.9	-2.1	-1.9	-2.3	-2.3	-1.9	-1.8	-1.8	-1.7	-1.9	-2.1
Neuroticism	0.7	1.7	2.7	-1.0	-1.4	-1.5	0.2	-1.3	-1.5	-1.0	-1.5	-1.5	-1.5	-1.3	-1.3	-1.6	-1.3	-1.4	-1.1	-1.5	-0.9
Average weekly spirits intake	0.7	0.8	1.8	-1.0	-0.9	-1.3	-0.4	-0.8	-0.8	-0.9	-0.8	-0.7	-0.8	-0.7	-0.7	-0.8	-1.0	-0.9	-1.3	-0.8	-1.2
Sensitivity / hurt feelings	0.7	1.2	1.6	-1.1	-1.2	-0.7	-0.6	-1.2	-1.3	-1.1	-1.2	-1.3	-1.2	-1.2	-1.2	-1.3	-1.1	-1.2	-0.6	-1.2	-0.7
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.8	-0.9	-1.0	-1.3	0.2	-0.9	-1.1	-0.8	-1.0	-1.0	-1.0	-0.8	-0.8	-1.1	-1.1	-1.1	-0.9	-1.0	-0.9
Taking other prescription medications	0.7	1.0	1.6	-0.7	-1.1	-1.3	0.7	-1.0	-0.9	-0.6	-1.2	-1.1	-1.2	-0.9	-1.0	-1.2	-1.0	-1.1	-1.0	-1.2	-0.5
Trunk fat-free mass	0.7	3.8	10.4	-2.0	-1.7	-0.6	-3.2	-1.9	-1.9	-2.4	-1.7	-2.0	-1.7	-2.3	-2.2	-1.7	-1.7	-1.7	-1.5	-1.7	-2.0
Alcohol intake versus 10 years previously	0.7	1.0	1.7	-1.3	-0.9	-0.8	-1.3	-1.0	-1.2	-1.2	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-1.1	-0.9	-0.8	-0.9	-1.3
Trunk predicted mass	0.7	3.9	10.8	-2.1	-1.8	-0.6	-3.3	-2.0	-2.0	-2.4	-1.8	-2.0	-1.8	-2.3	-2.2	-1.7	-1.7	-1.7	-1.5	-1.8	-2.0
High blood pressure (siblings)	0.7	1.1	1.7	-0.9	-1.2	-0.4	0.0	-1.2	-0.8	-0.9	-1.3	-1.1	-1.3	-1.2	-1.2	-1.1	-1.1	-1.2	-0.8	-1.3	-0.2
Arm predicted mass (right)	0.7	3.4	10.2	-1.9	-1.6	-0.2	-3.2	-1.9	-1.8	-2.3	-1.6	-1.9	-1.6	-2.2	-2.1	-1.6	-1.6	-1.6	-1.2	-1.6	-1.7
Hypertension (Self-reported)	0.7	2.0	3.5	-1.2	-1.5	-1.9	0.5	-1.4	-1.2	-1.0	-1.5	-1.3	-1.5	-1.2	-1.2	-1.5	-1.5	-1.6	-1.8	-1.5	-1.1
Mood swings	0.7	1.3	2.0	-1.0	-1.3	-1.1	0.1	-1.2	-1.3	-0.9	-1.3	-1.3	-1.3	-1.1	-1.1	-1.4	-1.2	-1.3	-0.8	-1.3	-0.7
Ever taken oral contraceptive pill	0.7	0.8	2.7	0.6	0.9	1.6	-0.2	0.8	0.7	0.6	0.9	0.8	0.9	0.8	0.8	0.9	0.8	0.9	1.6	0.9	0.9
Irritable Bowel Disease (IBD)	0.6	1.3	2.1	-1.1	-1.1	-0.2	-1.4	-1.2	-1.2	-1.3	-1.2	-1.3	-1.2	-1.4	-1.4	-1.1	-1.1	-1.1	-0.7	-1.2	-0.9
Number of treatments/medications taken	0.6	1.0	1.4	-0.9	-1.1	-0.5	-0.4	-1.1	-1.1	-1.0	-1.1	-1.2	-1.1	-1.1	-1.1	-1.2	-1.0	-1.1	-0.5	-1.1	-0.6
Medication: Levothyroxine sodium	0.6	1.0	1.9	-0.9	-1.0	-1.4	-0.1	-1.0	-1.0	-0.8	-1.0	-0.9	-1.0	-0.8	-0.9	-1.0	-1.1	-1.0	-1.2	-1.0	-1.0
Chronic bronchitis/emphysema (father)	0.6	0.6	0.9	-0.7	-0.8	-0.6	-0.5	-0.9	-0.8	-0.8	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-0.7	-0.8	-0.8	-0.9	-0.6
Pain all over the body in last month	0.6	0.7	3.4	-0.5	-0.7	-1.8	0.6	-0.6	-0.9	-0.4	-0.7	-0.7	-0.7	-0.4	-0.4	-0.9	-0.7	-0.7	-1.1	-0.7	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.1	-0.6	-0.9	-1.0	0.2	-0.8	-0.9	-0.6	-1.0	-1.0	-1.0	-0.8	-0.8	-1.0	-0.8	-0.9	-0.8	-1.0	-0.6
Pulse wave Arterial Stiffness index	0.6	0.7	3.5	-0.6	-0.4	-1.7	-0.8	-0.5	-0.5	-0.6	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.5	-0.5	-1.9	-0.4	-1.5
Pulse wave reflection index	0.6	0.8	1.9	-0.9	-0.8	-0.9	-0.7	-0.9	-0.6	-0.9	-0.8	-0.7	-0.8	-0.8	-0.8	-0.7	-0.9	-0.9	-1.4	-0.8	-1.0
Number of full brothers	0.6	0.8	4.5	0.2	1.0	0.0	-2.1	0.7	0.2	0.1	1.1	0.7	1.1	0.5	0.6	0.9	0.8	1.0	-0.2	1.1	-0.9
Migraine (self-reported)	0.6	0.7	2.0	0.7	0.9	1.4	-0.2	0.8	0.8	0.6	0.8	0.7	0.8	0.6	0.7	0.9	0.9	0.9	1.3	0.8	0.9
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.5	-0.8	-0.9	-1.2	0.1	-0.8	-1.0	-0.7	-0.9	-0.9	-0.9	-0.7	-0.7	-1.0	-0.9	-0.9	-0.8	-0.9	-0.9
Medication: Blood pressure	0.6	1.2	1.6	-1.1	-1.2	-1.3	0.3	-1.1	-1.1	-0.9	-1.2	-1.1	-1.2	-0.9	-0.9	-1.3	-1.3	-1.3	-0.9	-1.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.0	-0.8	-0.9	-1.0	0.3	-0.9	-0.9	-0.6	-0.9	-0.9	-0.9	-0.7	-0.7	-1.0	-1.0	-1.0	-0.7	-0.9	-0.6
Reaction Time	0.5	0.9	1.3	0.8	1.1	-0.3	0.3	1.1	0.9	0.9	1.1	1.1	1.1	1.2	1.2	1.1	0.9	1.1	-0.1	1.1	-0.1
Breast Cancer	0.5	1.3	2.8	-1.3	-0.9	-1.1	-1.6	-1.0	-1.2	-1.3	-0.9	-1.0	-0.9	-1.0	-1.0	-0.9	-1.1	-1.0	-1.3	-0.9	-1.7
Ovarian Cancer	0.5	0.7	4.1	0.7	0.6	2.0	-0.4	0.5	0.8	0.4	0.5	0.5	0.5	0.2	0.2	0.7	0.8	0.7	1.4	0.5	1.2
Allergy or Eczema	0.5	1.3	3.2	-0.8	-1.2	-1.8	0.7	-1.0	-1.0	-0.7	-1.2	-1.1	-1.2	-0.9	-1.0	-1.3	-1.1	-1.2	-1.5	-1.2	-0.9
Alcohol usually taken with meals	0.5	0.8	1.4	0.6	1.1	0.5	-0.5	1.0	0.7	0.6	1.2	1.1	1.2	1.1	1.1	1.1	0.9	1.1	0.6	1.2	0.1
Fluid intelligence score	0.5	1.0	2.7	0.8	1.1	1.7	-0.5	0.9	0.8	0.7	1.1	0.9	1.1	0.8	0.8	1.0	1.0	1.1	1.5	1.1	0.9
Father’s age at death	0.5	0.6	4.8	-0.2	-0.5	-2.2	0.8	-0.3	-0.6	-0.1	-0.5	-0.4	-0.5	-0.2	-0.2	-0.6	-0.5	-0.5	-1.6	-0.5	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.3	-0.4	-0.9	-1.5	0.7	-0.8	-1.0	-0.4	-0.9	-1.0	-0.9	-0.7	-0.7	-1.1	-0.7	-0.9	-0.9	-0.9	-0.7
Depression (self-reported)	0.5	0.6	1.4	1.1	0.8	0.0	1.2	0.9	0.7	1.0	0.8	0.7	0.8	0.8	0.8	0.6	0.9	0.8	0.5	0.8	0.7
Birth weight	0.5	1.0	1.8	-1.0	-0.9	-0.6	-1.4	-1.0	-1.0	-1.1	-0.9	-1.1	-0.9	-1.2	-1.1	-0.9	-0.9	-0.9	-1.1	-0.9	-1.0
Arm fat-free mass (right)	0.5	2.8	9.2	-1.7	-1.4	-0.2	-3.0	-1.6	-1.7	-2.0	-1.4	-1.7	-1.4	-2.0	-1.9	-1.4	-1.4	-1.4	-1.1	-1.4	-1.6
Pulse wave peak to peak time	0.5	0.6	3.3	0.5	0.3	1.7	0.6	0.4	0.4	0.5	0.3	0.3	0.3	0.3	0.3	0.3	0.4	0.3	1.8	0.3	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.1	0.9	0.4	1.1	1.3	0.5	0.7	0.8	0.4	0.5	0.4	0.5	0.5	0.4	0.6	0.5	1.3	0.4	1.5
Leg pain on walking	0.5	0.6	2.0	-0.9	-0.7	-0.0	-1.4	-0.8	-0.8	-1.0	-0.7	-0.8	-0.7	-0.9	-0.9	-0.6	-0.7	-0.7	-0.4	-0.7	-0.7
Medication: Aspirin	0.5	0.7	1.3	1.0	0.8	-0.3	1.1	0.9	0.7	1.0	0.8	0.8	0.8	1.0	0.9	0.7	0.9	0.8	0.3	0.8	0.4
Smoking status: Current	0.5	0.8	1.2	0.9	1.0	-0.6	0.8	1.0	0.7	1.0	1.0	0.9	1.0	1.1	1.1	0.8	0.9	1.0	-0.0	1.0	0.1
Age started oral contraceptive pill	0.5	0.6	4.9	-0.0	-0.2	-2.2	1.7	-0.0	-0.1	0.3	-0.1	0.1	-0.1	0.4	0.4	-0.2	-0.4	-0.3	-1.5	-0.1	-0.8
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.7	1.0	0.9	1.6	0.5	0.9	0.9	0.9	0.9	0.8	0.9	0.8	0.8	0.9	1.0	0.9	1.6	0.9	1.4
Lung FEV1/FVC ratio	0.4	2.0	5.0	-1.5	-1.1	-1.3	-2.2	-1.3	-1.5	-1.6	-1.1	-1.3	-1.1	-1.4	-1.4	-1.2	-1.2	-1.1	-1.6	-1.1	-2.0
Chronotype (morning person)	0.4	0.8	1.4	0.9	1.0	-0.2	1.0	1.0	0.9	1.0	1.0	1.0	1.0	1.2	1.1	0.9	0.8	0.9	0.3	1.0	0.4
Medication: Co-codamol	0.4	0.5	0.9	-0.3	-0.8	-0.4	0.9	-0.7	-0.4	-0.3	-0.9	-0.7	-0.9	-0.6	-0.7	-0.8	-0.7	-0.8	-0.4	-0.9	0.1
Impedance of leg (right)	0.4	1.7	8.7	1.4	1.0	-0.8	2.9	1.2	1.1	1.7	1.0	1.2	1.0	1.6	1.5	0.9	1.0	0.9	0.3	1.0	0.9
High blood pressure	0.4	1.1	2.3	-0.8	-1.2	-1.5	0.8	-1.0	-0.8	-0.7	-1.2	-1.0	-1.2	-0.8	-0.9	-1.1	-1.2	-1.2	-1.4	-1.2	-0.7
Qualifications: None of the above	0.4	0.8	5.6	-0.3	-0.5	-2.4	1.1	-0.4	-0.7	-0.1	-0.5	-0.5	-0.5	-0.1	-0.2	-0.7	-0.6	-0.6	-1.6	-0.5	-1.1
Noisy workplace	0.4	0.5	0.7	-0.7	-0.8	-0.8	0.1	-0.8	-0.7	-0.6	-0.8	-0.7	-0.8	-0.7	-0.7	-0.8	-0.8	-0.9	-0.7	-0.8	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	1.0	6.3	0.5	0.5	2.5	0.1	0.5	0.8	0.4	0.5	0.6	0.5	0.4	0.4	0.6	0.5	0.5	2.1	0.5	1.7
Mouth/teeth dental problems: Dentures	0.4	0.6	1.0	0.7	0.9	0.3	-0.0	0.9	0.9	0.7	1.0	1.0	1.0	0.9	0.9	1.0	0.8	0.9	0.1	1.0	0.3
Tense / ‘highly strung’	0.4	0.6	3.0	0.6	0.4	1.6	0.8	0.5	0.6	0.6	0.4	0.4	0.4	0.4	0.4	0.4	0.5	0.4	1.7	0.4	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.6	0.8	0.3	1.3	1.2	0.4	0.4	0.7	0.2	0.2	0.2	0.3	0.3	0.2	0.6	0.4	1.6	0.2	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.8	-0.7	-0.9	-0.6	0.7	-0.7	-0.7	-0.5	-0.8	-0.7	-0.8	-0.5	-0.6	-0.8	-0.9	-0.9	-0.4	-0.8	-0.2
Shortness of breath walking on level ground	0.4	0.5	0.8	-0.7	-0.7	-0.6	-0.5	-0.7	-0.9	-0.7	-0.7	-0.8	-0.7	-0.7	-0.7	-0.8	-0.7	-0.7	-0.4	-0.7	-0.7
Medication for pain relief, constipation, heartburn	0.4	0.6	2.5	0.6	0.6	1.6	0.2	0.6	0.9	0.5	0.6	0.7	0.6	0.5	0.6	0.8	0.6	0.6	1.1	0.6	1.2
Medication: Aspirin	0.4	0.5	1.4	0.9	0.7	-0.5	1.2	0.8	0.6	0.9	0.7	0.7	0.7	0.9	0.9	0.6	0.7	0.7	0.1	0.7	0.3
Supplements: Vitamin C	0.4	0.5	0.8	-0.8	-0.7	-0.2	-0.9	-0.7	-0.8	-0.8	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.2	-0.7	-0.6
Commuting to job workplace: Walk	0.4	0.4	2.1	0.8	0.4	-0.1	1.4	0.5	0.8	0.8	0.4	0.6	0.4	0.6	0.6	0.5	0.5	0.4	0.1	0.4	0.7
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.8	-0.7	-0.8	0.1	-0.3	-0.8	-0.8	-0.7	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-0.7	-0.8	-0.0	-0.9	-0.1
Alcohol drinker status: Never	0.4	0.5	0.9	0.4	0.9	0.0	-0.5	0.8	0.5	0.5	0.9	0.8	0.9	0.8	0.9	0.9	0.7	0.8	0.1	0.9	-0.2
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.3	0.8	1.1	1.5	-0.7	0.9	0.8	0.6	1.1	0.9	1.1	0.7	0.8	1.1	1.1	1.1	1.3	1.1	0.7
Heart disease (siblings)	0.4	0.5	3.0	-0.7	-0.4	-0.2	-1.7	-0.6	-0.7	-0.9	-0.4	-0.6	-0.4	-0.7	-0.7	-0.4	-0.5	-0.4	-0.6	-0.4	-1.0
Heel T-Score	0.3	2.2	4.0	-1.2	-1.6	0.4	-1.4	-1.6	-1.3	-1.6	-1.7	-1.8	-1.7	-2.0	-2.0	-1.6	-1.3	-1.5	-0.3	-1.7	-0.3
Diabetes (father)	0.3	0.4	1.4	0.4	0.5	1.2	0.2	0.5	0.5	0.5	0.5	0.6	0.5	0.5	0.5	0.6	0.5	0.5	1.2	0.5	0.9
Diabetes (mother)	0.3	0.3	0.7	0.8	0.6	-0.4	0.7	0.6	0.4	0.7	0.6	0.4	0.6	0.6	0.6	0.4	0.7	0.6	-0.0	0.6	0.2
Qualifications: CSEs or equivalent	0.3	0.4	0.7	-0.6	-0.7	0.3	-0.7	-0.7	-0.6	-0.7	-0.7	-0.7	-0.7	-0.8	-0.8	-0.6	-0.6	-0.6	-0.0	-0.7	-0.2
Impedance of leg (left)	0.3	1.6	9.9	1.3	0.9	-1.2	3.1	1.1	0.9	1.6	0.9	1.1	0.9	1.5	1.5	0.7	0.8	0.8	0.0	0.9	0.7
Diabetes (self-reported)	0.3	0.4	1.0	0.7	0.6	-1.0	1.0	0.7	0.4	0.8	0.6	0.6	0.6	0.8	0.8	0.4	0.6	0.6	-0.4	0.6	-0.1
Medication: Ramipril	0.3	0.4	3.7	0.8	0.3	-0.3	1.9	0.5	0.5	0.9	0.3	0.4	0.3	0.7	0.6	0.2	0.4	0.3	0.3	0.3	0.7
Standing height	0.3	2.6	3.3	-1.6	-1.6	-1.2	-1.4	-1.7	-1.5	-1.7	-1.6	-1.6	-1.6	-1.8	-1.7	-1.5	-1.6	-1.6	-1.8	-1.6	-1.6
Hair/balding pattern: Pattern 4	0.3	0.7	2.5	0.4	0.7	1.6	0.0	0.7	0.8	0.5	0.7	0.8	0.7	0.7	0.7	0.9	0.6	0.7	1.4	0.7	1.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	3.0	-0.4	-0.3	1.7	-1.2	-0.4	-0.1	-0.6	-0.4	-0.4	-0.4	-0.7	-0.7	-0.2	-0.2	-0.3	0.9	-0.4	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.9	-0.7	-0.6	-0.9	-0.2	-0.6	-0.8	-0.6	-0.6	-0.6	-0.6	-0.5	-0.5	-0.7	-0.7	-0.6	-0.6	-0.6	-0.8
Eye problems/disorders: None of the above	0.3	0.4	3.8	0.5	0.2	-0.3	1.9	0.4	0.6	0.7	0.2	0.5	0.2	0.6	0.5	0.3	0.2	0.1	0.0	0.2	0.7
Average weekly red wine intake	0.3	0.4	1.8	0.1	0.6	1.4	-0.6	0.5	0.5	0.2	0.6	0.6	0.6	0.5	0.5	0.7	0.4	0.6	1.1	0.6	0.5
Loneliness, isolation	0.3	0.4	1.1	-0.6	-0.5	-1.1	-0.5	-0.5	-0.9	-0.6	-0.5	-0.7	-0.5	-0.5	-0.5	-0.7	-0.6	-0.5	-0.7	-0.5	-0.9
Medication for cholesterol	0.3	0.5	1.1	0.8	0.6	1.0	0.4	0.6	0.9	0.7	0.6	0.6	0.6	0.5	0.5	0.7	0.7	0.6	0.6	0.6	1.0
Back pain experienced in last month	0.3	0.4	1.6	-0.3	-0.4	1.3	-0.9	-0.5	-0.3	-0.5	-0.5	-0.6	-0.5	-0.8	-0.7	-0.4	-0.2	-0.3	0.8	-0.5	0.5
Breast cancer (self-reported)	0.3	0.3	0.5	-0.5	-0.6	0.2	-0.4	-0.6	-0.5	-0.6	-0.7	-0.7	-0.7	-0.7	-0.7	-0.6	-0.6	-0.6	-0.0	-0.7	-0.0
Medication: Gliclazide	0.3	0.4	3.0	-0.2	-0.2	-1.7	0.4	-0.1	-0.4	-0.1	-0.1	-0.1	-0.1	0.1	0.0	-0.3	-0.3	-0.2	-1.2	-0.1	-1.0
Number of self-reported non-cancer illnesses	0.3	0.6	0.8	-0.6	-0.9	-0.7	-0.0	-0.8	-0.7	-0.7	-0.9	-0.8	-0.9	-0.8	-0.8	-0.9	-0.8	-0.8	-0.7	-0.9	-0.5
Ever smoked	0.3	0.5	1.9	0.8	0.6	0.1	1.4	0.7	0.6	0.9	0.5	0.6	0.5	0.8	0.7	0.5	0.6	0.6	0.6	0.5	0.8
Ulcerative Colitis (UC)	0.2	0.3	0.8	-0.6	-0.6	0.1	-0.9	-0.6	-0.6	-0.7	-0.6	-0.7	-0.6	-0.8	-0.7	-0.6	-0.5	0.0	-0.2	-0.6	-0.4
Age at First Birth	0.2	0.2	0.8	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.9	0.8	0.8	0.0	0.0	0.0	0.0	0.9	0.0
Blood Eosinophil Count	0.2	1.4	3.3	-1.2	-1.1	-1.8	-0.7	-1.1	-1.3	-1.1	-1.0	-1.1	-1.0	-0.9	-0.9	-1.2	-1.2	-1.1	-1.6	-1.0	-1.6
Hand grip strength (left)	0.2	0.5	5.1	-0.5	0.2	1.2	-2.3	-0.1	-0.1	-0.6	0.2	0.0	0.2	-0.3	-0.2	0.3	0.0	0.2	0.6	0.2	-0.2
Ever had hysterectomy (womb removed)	0.2	0.2	1.0	0.2	0.3	0.8	0.4	0.4	0.3	0.4	0.4	0.4	0.4	0.4	0.4	0.3	0.3	0.3	1.0	0.4	0.7
Vitamin and mineral supplements	0.2	0.3	0.6	-0.4	-0.5	-0.1	-0.8	-0.5	-0.2	-0.6	-0.5	-0.5	-0.5	-0.7	-0.7	-0.3	-0.4	-0.4	-0.8	-0.5	-0.4
Severe depression (siblings)	0.2	0.2	1.3	0.4	0.4	0.8	0.1	0.4	0.1	0.3	0.4	0.2	0.4	0.3	0.3	0.2	0.4	0.4	1.2	0.4	0.6
Fed-up feelings	0.2	0.4	3.2	0.3	-0.5	-0.8	1.8	-0.3	-0.3	0.3	-0.5	-0.5	-0.5	-0.3	-0.3	-0.7	-0.2	-0.4	-0.1	-0.5	0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	0.5	0.4	-0.3	0.7	0.5	0.3	0.6	0.5	0.4	0.5	0.6	0.6	0.3	0.4	0.4	0.2	0.5	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.4	-0.1	-0.7	-0.9	1.2	-0.5	-0.4	-0.1	-0.7	-0.6	-0.7	-0.4	-0.5	-0.7	-0.5	-0.6	-0.6	-0.7	-0.0
Medication: Simvastatin	0.2	0.3	1.9	0.3	0.2	-1.4	1.1	0.3	0.3	0.5	0.2	0.4	0.2	0.5	0.5	0.2	0.1	0.1	-1.0	0.2	-0.4
Impedance of arm (right)	0.2	0.8	5.4	-0.2	-0.5	-2.3	2.2	-0.2	-0.3	0.3	-0.5	-0.1	-0.5	0.3	0.2	-0.5	-0.6	-0.6	-1.4	-0.5	-0.6
Hair/balding pattern: Pattern 3	0.2	0.2	0.9	0.3	0.6	0.6	-0.9	0.5	0.2	0.1	0.6	0.3	0.6	0.3	0.3	0.5	0.5	0.6	0.6	0.6	-0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	7.6	-0.6	-0.2	1.7	-2.8	-0.5	-0.5	-1.0	-0.2	-0.6	-0.2	-0.9	-0.8	-0.2	-0.1	-0.1	0.8	-0.2	-0.1
Prospective memory result	0.2	0.2	2.6	0.4	-0.0	-0.4	1.6	0.1	0.3	0.5	-0.0	0.2	-0.0	0.3	0.3	0.0	0.1	-0.0	-0.1	-0.0	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	4.8	-0.7	-0.4	0.8	-2.2	-0.6	-0.7	-1.0	-0.4	-0.7	-0.4	-0.9	-0.8	-0.4	-0.4	-0.3	0.3	-0.4	-0.5
Breastfed as a baby	0.2	0.2	0.3	0.6	0.6	-0.1	0.4	0.6	0.5	0.6	0.6	0.5	0.6	0.5	0.5	0.5	0.6	0.6	0.1	0.6	0.2
Peak expiratory flow (PEF)	0.2	0.4	4.0	-0.5	-0.1	1.2	-2.0	-0.3	-0.3	-0.7	-0.1	-0.3	-0.1	-0.5	-0.5	-0.0	-0.1	-0.0	0.5	-0.1	-0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.2	-0.6	-0.4	-0.2	-1.1	-0.5	-0.6	-0.7	-0.4	-0.5	-0.4	-0.6	-0.6	-0.4	-0.4	-0.4	-0.5	-0.4	-0.6
Worry too long after embarrassment	0.2	0.3	2.2	0.0	-0.5	-0.6	1.5	-0.3	-0.3	0.1	-0.5	-0.4	-0.5	-0.2	-0.2	-0.6	-0.4	-0.5	-0.1	-0.5	0.3
Medication: Blood pressure	0.2	0.3	2.0	0.2	-0.1	-1.3	1.4	0.1	0.2	0.4	-0.1	0.1	-0.1	0.3	0.2	-0.1	-0.1	-0.1	-1.0	-0.1	-0.2
Mean time to correctly identify matches	0.2	0.5	2.1	0.4	0.5	-1.4	0.8	0.5	0.4	0.6	0.5	0.6	0.5	0.8	0.7	0.5	0.3	0.4	-1.0	0.5	-0.6
Comparative height size at age 10	0.2	1.2	1.9	-1.2	-1.0	-0.8	-1.4	-1.1	-1.1	-1.3	-1.0	-1.0	-1.0	-1.1	-1.1	-1.0	-1.1	-1.1	-1.2	-1.0	-1.2
Had major operations	0.2	0.2	1.5	0.5	0.2	-1.0	1.2	0.3	0.2	0.5	0.2	0.2	0.2	0.4	0.4	0.1	0.2	0.2	-0.6	0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.5	-0.9	-0.6	-0.3	-1.2	-0.7	-0.8	-0.9	-0.5	-0.6	-0.5	-0.6	-0.6	-0.6	-0.7	-0.6	-0.4	-0.5	-0.9
Ever had bowel cancer screening	0.2	0.3	3.0	0.3	0.0	-1.1	1.7	0.2	0.1	0.6	0.0	0.2	0.0	0.5	0.4	-0.1	0.0	0.0	-0.3	0.0	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.1	-0.6	-0.3	-1.0	-0.4	-0.3	-0.6	-0.4	-0.2	-0.2	-0.2	-0.1	-0.1	-0.3	-0.5	-0.3	-0.6	-0.2	-1.0
Friendships satisfaction	0.2	0.3	2.6	0.6	0.1	0.1	1.6	0.2	0.1	0.6	0.0	-0.0	0.0	0.2	0.2	-0.2	0.3	0.1	0.8	0.0	0.9
Qualifications: nursing, teaching	0.2	0.4	1.9	-0.6	-0.5	0.7	-1.4	-0.6	-0.4	-0.8	-0.5	-0.6	-0.5	-0.8	-0.8	-0.4	-0.4	-0.4	0.0	-0.5	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	2.1	0.1	0.2	0.9	-1.4	0.0	-0.0	-0.3	0.1	-0.1	0.1	-0.3	-0.3	0.1	0.3	0.3	0.4	0.1	0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	-0.2	-0.5	-0.2	0.0	-0.5	-0.4	-0.4	-0.6	-0.5	-0.6	-0.6	-0.6	-0.5	-0.4	-0.5	-0.3	-0.6	-0.1
Miserableness	0.2	0.4	4.2	0.5	-0.1	-1.3	2.0	0.1	-0.1	0.6	-0.2	-0.1	-0.2	0.2	0.2	-0.4	0.1	-0.1	-0.4	-0.2	0.1
Financial situation satisfaction	0.2	0.3	2.2	0.6	0.3	-0.8	1.5	0.4	0.1	0.7	0.2	0.2	0.2	0.5	0.5	-0.0	0.4	0.3	0.0	0.2	0.2
Medication: Atorvastatin	0.2	0.3	2.1	0.5	0.3	-0.7	1.5	0.4	0.3	0.7	0.3	0.4	0.3	0.6	0.6	0.2	0.3	0.3	-0.1	0.3	0.3
Risk taking	0.2	0.3	0.4	0.3	0.6	0.4	-0.1	0.6	0.5	0.4	0.7	0.7	0.7	0.7	0.7	0.7	0.5	0.6	0.4	0.7	0.1
Unable to work because of sickness or disability	0.2	0.2	1.6	-0.6	-0.2	0.1	-1.2	-0.3	-0.6	-0.6	-0.2	-0.4	-0.2	-0.3	-0.3	-0.3	-0.3	-0.2	0.1	-0.2	-0.6
Impedance of whole body	0.2	1.0	8.1	0.7	0.4	-1.6	2.8	0.6	0.5	1.2	0.4	0.7	0.4	1.1	1.0	0.3	0.3	0.3	-0.5	0.4	0.3
Alzheimer’s Disease (in father)	0.1	0.2	0.2	0.4	0.4	0.1	0.5	0.4	0.4	0.4	0.4	0.5	0.4	0.5	0.5	0.4	0.4	0.4	0.2	0.4	0.3
Lupus	0.1	0.2	0.7	0.0	0.0	0.0	0.0	0.0	-0.6	0.0	-0.7	-0.7	-0.7	-0.8	-0.8	0.0	0.0	0.0	0.0	-0.7	0.0
Blood Platelet Count	0.1	1.1	4.5	-0.5	-1.0	-2.1	1.7	-0.8	-0.8	-0.2	-1.0	-0.8	-1.0	-0.4	-0.5	-1.1	-1.0	-1.0	-1.4	-1.0	-0.7
Systolic Blood Pressure	0.1	0.5	3.1	-0.3	-0.8	-0.5	1.8	-0.6	-0.3	-0.1	-0.8	-0.4	-0.8	-0.2	-0.3	-0.7	-0.8	-0.8	-0.1	-0.8	0.4
Smoking Status	0.1	0.3	0.9	0.7	0.5	-0.9	0.9	0.5	0.4	0.7	0.4	0.4	0.4	0.5	0.5	0.3	0.6	0.5	-0.6	0.4	-0.1
Cardiovascular Disease	0.1	0.2	2.1	-0.1	-0.5	-0.5	1.5	-0.3	-0.1	0.1	-0.5	-0.2	-0.5	-0.1	-0.1	-0.4	-0.4	-0.5	-0.2	-0.5	0.3
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.5	0.1	-0.3	-0.2	1.2	-0.2	-0.4	0.2	-0.4	-0.4	-0.4	-0.2	-0.2	-0.6	-0.2	-0.3	0.5	-0.4	0.4
Angina	0.1	0.1	0.9	-0.2	0.1	-0.1	-1.0	0.0	-0.2	-0.2	0.1	-0.1	0.1	-0.1	-0.1	0.0	0.1	0.1	-0.1	0.1	-0.4
Supplements: Zinc	0.1	0.1	0.5	-0.2	-0.1	0.6	-0.4	-0.1	-0.3	-0.2	-0.1	-0.2	-0.1	-0.2	-0.2	-0.2	-0.1	-0.1	0.7	-0.1	0.1
Pack years adult smoking proportion	0.1	0.1	0.3	0.3	0.3	0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.6	0.3	0.5
Hand grip strength (right)	0.1	0.3	3.8	-0.4	0.0	0.9	-1.9	-0.2	-0.3	-0.6	0.1	-0.2	0.1	-0.4	-0.3	0.0	-0.0	0.0	0.5	0.1	-0.3
Current tobacco smoking	0.1	0.2	0.6	0.3	0.5	-0.8	0.2	0.5	0.1	0.4	0.5	0.4	0.5	0.6	0.6	0.3	0.4	0.5	-0.3	0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.9	-0.5	-0.3	-0.1	-0.9	-0.4	-0.3	-0.6	-0.3	-0.3	-0.3	-0.4	-0.4	-0.2	-0.4	-0.3	-0.5	-0.3	-0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.3	-0.3	-0.2	-0.3	-0.6	-0.3	-0.4	-0.3	-0.2	-0.4	-0.2	-0.3	-0.3	-0.3	-0.2	-0.2	-0.3	-0.2	-0.4
Sitting height	0.1	0.4	2.2	-0.5	-0.4	0.9	-1.5	-0.5	-0.3	-0.7	-0.4	-0.5	-0.4	-0.8	-0.7	-0.3	-0.3	-0.3	0.1	-0.4	-0.1
High blood pressure (mother)	0.1	0.1	0.3	0.3	0.4	0.6	-0.2	0.3	0.3	0.2	0.4	0.3	0.4	0.3	0.3	0.4	0.4	0.4	0.5	0.4	0.3
Past tobacco smoking	0.1	0.2	2.2	-0.6	-0.2	0.6	-1.5	-0.3	-0.4	-0.6	-0.1	-0.3	-0.1	-0.4	-0.3	-0.1	-0.3	-0.2	0.3	-0.1	-0.4
Nervous feelings	0.1	0.2	1.2	-0.1	-0.4	-0.5	1.1	-0.2	-0.3	0.1	-0.4	-0.3	-0.4	-0.1	-0.1	-0.4	-0.3	-0.4	-0.0	-0.4	0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	-0.3	-0.4	-0.5	-0.2	-0.4	-0.3	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.3	-0.4	-0.4	-0.6	-0.4	-0.4
Had menopause	0.1	0.1	0.2	-0.2	-0.4	-0.2	0.2	-0.4	-0.3	-0.3	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.2	-0.4	-0.1
Forced vital capacity (FVC)	0.1	0.6	4.2	-0.5	-0.2	1.4	-2.0	-0.4	-0.5	-0.8	-0.3	-0.5	-0.3	-0.8	-0.7	-0.3	-0.2	-0.2	0.8	-0.3	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.9	-0.6	-0.4	-0.4	-0.9	-0.4	-0.4	-0.6	-0.3	-0.3	-0.3	-0.4	-0.4	-0.3	-0.5	-0.4	-0.7	-0.3	-0.8
Financial difficulties in last 2 years	0.1	0.1	1.2	-0.0	-0.1	-1.1	0.7	-0.0	-0.2	0.1	-0.1	-0.0	-0.1	0.2	0.2	-0.2	-0.1	-0.1	-0.6	-0.1	-0.4
Mouth/teeth dental problems	0.1	0.2	0.5	-0.3	-0.5	-0.7	0.5	-0.4	-0.6	-0.2	-0.5	-0.5	-0.5	-0.3	-0.4	-0.6	-0.5	-0.5	-0.2	-0.5	-0.3
Worrier / anxious feelings	0.1	0.1	1.0	0.0	0.0	-1.0	0.8	0.1	-0.2	0.3	0.1	0.0	0.1	0.3	0.3	-0.1	-0.1	-0.0	-0.2	0.1	-0.3
Falls in the last year	0.1	0.2	1.1	0.5	0.2	1.0	0.2	0.2	0.3	0.2	0.1	0.1	0.1	-0.0	-0.0	0.1	0.4	0.2	0.8	0.1	0.9
Pulse rate	0.1	0.2	1.4	-0.1	-0.2	-1.2	0.2	-0.1	-0.4	-0.1	-0.2	-0.3	-0.2	-0.1	-0.1	-0.4	-0.2	-0.2	-0.7	-0.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.1	-0.3	0.3	0.5	-0.2	0.1	-0.0	-0.4	-0.3	-0.4	-0.3	-0.3	-0.2	-0.1	-0.3	0.1	-0.4	0.5
Illnesses of mother	0.1	0.2	0.4	0.2	0.4	-0.4	0.4	0.4	0.3	0.4	0.5	0.5	0.5	0.6	0.6	0.4	0.3	0.4	-0.1	0.5	-0.1
Impedance of arm (left)	0.1	0.6	4.6	-0.1	-0.3	-2.0	2.1	-0.1	-0.1	0.4	-0.3	0.0	-0.3	0.4	0.3	-0.3	-0.5	-0.4	-1.2	-0.3	-0.4
Medication: Paracetamol	0.1	0.2	1.7	-0.1	-0.1	-1.3	0.3	-0.1	-0.4	-0.0	-0.1	-0.2	-0.1	0.0	-0.0	-0.3	-0.2	-0.2	-0.8	-0.1	-0.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.6	-0.2	0.1	1.3	-0.9	0.0	-0.1	-0.2	0.2	0.0	0.2	-0.0	0.0	0.1	0.1	0.1	1.2	0.2	0.3
Glaucoma (self-reported)	0.1	0.1	0.3	0.1	-0.2	-0.5	0.3	-0.2	-0.1	-0.0	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.0	-0.2	-0.6	-0.3	-0.1
Medication: Amlodipine	0.1	0.1	0.2	0.0	0.4	0.5	-0.4	0.3	0.3	0.1	0.4	0.4	0.4	0.4	0.4	0.4	0.2	0.3	0.4	0.4	0.1
Forced vital capacity (FVC), Best measure	0.1	0.4	2.7	-0.5	-0.3	1.1	-1.6	-0.5	-0.5	-0.8	-0.4	-0.6	-0.4	-0.8	-0.7	-0.4	-0.3	-0.3	0.7	-0.4	-0.0
Comparative body size at age 10	0.1	0.3	0.6	-0.6	-0.5	0.2	-0.8	-0.6	-0.3	-0.6	-0.5	-0.5	-0.5	-0.6	-0.6	-0.4	-0.5	-0.5	-0.4	-0.5	-0.3
Number of children fathered	0.1	0.1	0.7	0.5	0.2	-0.3	0.8	0.2	0.4	0.4	0.1	0.2	0.1	0.2	0.2	0.2	0.3	0.2	-0.3	0.1	0.2
Medication: Ibuprofen	0.1	0.1	0.3	-0.2	-0.3	0.5	-0.3	-0.4	-0.4	-0.3	-0.4	-0.5	-0.4	-0.5	-0.5	-0.4	-0.2	-0.3	0.5	-0.4	0.2
Medication: Allopurinol	0.1	0.1	0.9	0.2	-0.1	-0.5	1.0	0.0	-0.1	0.3	-0.1	-0.0	-0.1	0.1	0.1	-0.2	-0.0	-0.1	-0.0	-0.1	0.1
Heart disease (mother)	0.1	0.1	0.7	0.1	-0.3	-0.3	0.8	-0.2	0.1	0.1	-0.3	-0.2	-0.3	-0.1	-0.2	-0.2	-0.2	-0.2	-0.3	-0.3	0.2
Pulse rate, automated reading	0.1	0.3	0.6	0.6	0.5	0.7	0.1	0.5	0.4	0.5	0.5	0.3	0.5	0.3	0.4	0.4	0.6	0.6	0.8	0.5	0.6
Alcohol intake frequency.	0.1	0.2	1.3	-0.4	-0.0	-0.4	-1.2	-0.1	-0.4	-0.4	0.0	-0.2	0.0	-0.1	-0.1	-0.1	-0.2	-0.0	-0.4	0.0	-0.8
Smoking status: Previous	0.1	0.1	1.0	0.4	-0.0	-0.1	1.0	0.0	0.3	0.3	-0.1	0.0	-0.1	0.0	-0.0	-0.0	0.1	-0.0	-0.1	-0.1	0.5
Eye problems/disorders: Cataract	0.1	0.1	1.4	-0.2	-0.1	0.1	-1.2	-0.2	-0.5	-0.4	-0.1	-0.4	-0.1	-0.4	-0.4	-0.3	-0.0	-0.0	0.0	-0.1	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	0.1	0.5	0.7	-0.8	0.4	0.4	0.1	0.5	0.5	0.5	0.3	0.3	0.6	0.4	0.5	0.2	0.5	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.9	0.1	0.4	1.2	-1.4	0.2	0.2	-0.1	0.4	0.2	0.4	-0.1	-0.0	0.4	0.4	0.4	0.7	0.4	0.2
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.5	0.4	-0.4	-0.2	0.4	0.3	0.3	0.4	0.3	0.4	0.2	0.2	0.4	0.5	0.4	-0.5	0.4	-0.2
Wears glasses or contact lenses	0.1	0.1	0.4	-0.3	-0.3	-0.5	-0.4	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.6	-0.3	-0.5
Mother’s age at death	0.1	0.1	0.2	-0.1	-0.4	0.1	0.5	-0.4	-0.2	-0.2	-0.5	-0.5	-0.5	-0.4	-0.4	-0.5	-0.3	-0.4	0.1	-0.5	0.3
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.1	-0.5	-0.3	0.7	-0.4	-0.4	-0.2	-0.6	-0.6	-0.6	-0.5	-0.5	-0.6	-0.4	-0.5	-0.1	-0.6	0.1
Medication: Paracetamol	0.1	0.1	0.9	-0.3	-0.2	-0.9	-0.1	-0.2	-0.5	-0.2	-0.2	-0.3	-0.2	-0.2	-0.2	-0.4	-0.3	-0.2	-0.6	-0.2	-0.7
Medication: Lisinopril	0.1	0.1	0.8	-0.3	-0.1	-0.3	-0.9	-0.1	-0.3	-0.4	-0.0	-0.1	-0.0	-0.2	-0.2	-0.1	-0.2	-0.1	-0.4	-0.0	-0.6
Number of operations (self-reported)	0.1	0.1	0.5	-0.1	-0.2	0.7	-0.2	-0.2	-0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.3	-0.2	-0.1	-0.1	0.6	-0.2	0.5
Supplements: Calcium	0.1	0.1	0.6	-0.3	-0.3	0.8	-0.3	-0.3	-0.2	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.2	-0.2	-0.3	0.6	-0.3	0.4
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Depressed Affect (Nagel 2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Depression (Nagel 2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (Nagel 2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	0.1	-0.1	-0.0	0.0	-0.1	-0.0	-0.0	-0.1	-0.2	-0.1	-0.2	-0.2	-0.1	0.0	-0.1	-0.1	-0.1	0.0
Alzheimer’s Disease (including proxy)	0.0	0.0	0.0	0.1	-0.0	-0.1	0.2	-0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.0	0.0	-0.0	-0.2	-0.1	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	-0.0	0.0	-0.0	0.2	0.1	0.0	0.0	0.0	0.0	-0.0	0.0
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.1	0.3	-0.0	-0.3	0.4	0.0	-0.1	0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	0.2	0.0	-0.1	-0.1	0.1
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.9	1.6	-0.7	-0.9	-0.6	-1.1	-1.0	-0.8	-1.0	-1.0	-1.1	-1.0	-1.2	-1.2	-1.0	-0.7	-0.9	-1.2	-1.0	-0.8
Hair Pigment	0.0	0.0	0.1	-0.3	-0.1	0.3	-0.3	-0.1	-0.0	-0.2	-0.1	-0.0	-0.1	-0.1	-0.1	-0.0	-0.2	-0.1	0.1	-0.1	0.0
Tanning	0.0	0.1	0.8	0.2	-0.2	-0.2	0.9	-0.1	-0.0	0.2	-0.2	-0.1	-0.2	-0.0	-0.1	-0.2	-0.1	-0.2	0.0	-0.2	0.3
Stomach or abdominal pain in last month	0.0	0.0	0.2	-0.1	-0.2	-0.1	0.3	-0.1	-0.4	-0.0	-0.2	-0.3	-0.2	-0.1	-0.1	-0.4	-0.1	-0.1	0.4	-0.2	0.1
Medication: Atenolol	0.0	0.0	0.3	0.2	0.1	-0.3	0.5	0.1	0.2	0.2	0.1	0.1	0.1	0.2	0.2	0.1	0.1	0.1	-0.1	0.1	0.1
Had other major operations	0.0	0.0	0.3	0.2	0.1	0.2	0.5	0.1	0.0	0.2	0.1	0.0	0.1	0.1	0.1	-0.0	0.1	0.1	0.5	0.1	0.4
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	-0.0	-0.2	-0.1	-0.2	-0.2	-0.1	-0.2	-0.2	-0.2	-0.2	-0.3	-0.3	-0.2	-0.1	-0.1	-0.3	-0.2	-0.2
Number of live births	0.0	0.0	0.1	0.2	0.1	-0.3	0.3	0.2	0.0	0.2	0.1	0.1	0.1	0.2	0.2	0.0	0.2	0.1	-0.1	0.1	-0.1
Lung cancer (father)	0.0	0.0	0.2	-0.0	0.0	-0.1	-0.1	0.0	0.2	-0.0	0.1	0.1	0.1	0.1	0.1	0.2	-0.0	0.0	-0.4	0.1	-0.2
Loud music exposure frequency	0.0	0.0	0.5	0.0	-0.1	-0.3	0.7	-0.0	-0.0	0.1	-0.1	-0.0	-0.1	0.0	0.0	-0.1	-0.1	-0.1	-0.1	-0.1	0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.1	0.2	0.1	0.2	0.3	0.1	0.3	0.2	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.3
Gout (self-reported)	0.0	0.0	0.0	-0.1	0.1	-0.2	-0.1	0.1	-0.0	-0.0	0.1	0.1	0.1	0.1	0.1	0.1	-0.0	0.0	-0.1	0.1	-0.2
Health satisfaction	0.0	0.1	0.3	-0.2	-0.1	-0.1	-0.6	-0.1	-0.4	-0.3	-0.1	-0.3	-0.1	-0.2	-0.2	-0.2	-0.1	-0.1	0.0	-0.1	-0.3
Qualifications: College or University degree	0.0	0.0	0.2	-0.2	-0.2	0.4	0.1	-0.2	0.1	-0.1	-0.2	-0.0	-0.2	-0.1	-0.1	-0.0	-0.2	-0.2	0.2	-0.2	0.2
Angina (self-reported)	0.0	0.0	0.4	-0.0	0.2	-0.1	-0.6	0.1	-0.2	-0.1	0.2	0.0	0.2	0.1	0.1	0.1	0.1	0.2	-0.0	0.2	-0.4
Number of full sisters	0.0	0.0	0.1	-0.0	-0.1	-0.3	0.2	-0.1	-0.0	-0.0	-0.1	-0.0	-0.1	-0.0	-0.0	-0.1	-0.1	-0.1	-0.3	-0.1	-0.1
Suffer from ‘nerves’	0.0	0.1	0.1	0.3	0.3	-0.1	0.3	0.3	0.1	0.3	0.3	0.2	0.3	0.3	0.3	0.2	0.3	0.3	0.3	0.3	0.1
Overall health rating	0.0	0.0	0.0	0.0	0.2	-0.2	-0.1	0.1	-0.2	0.1	0.2	0.0	0.2	0.2	0.2	0.0	0.1	0.2	0.2	0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	0.3	0.3	-0.1	-0.1	0.2	0.2	0.2	0.3	0.2	0.3	0.1	0.2	0.3	0.3	0.3	-0.2	0.3	-0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	0.1	-0.2	-0.3	0.1	-0.2	-0.2	-0.1	-0.2	-0.3	-0.2	-0.3	-0.3	-0.3	-0.0	-0.2	-0.3	-0.2	-0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.2	-0.0	0.0	-0.3	-0.3	-0.0	0.0	-0.1	0.0	0.0	0.0	-0.0	-0.0	0.1	0.0	0.0	-0.4	0.0	-0.3
Fractured/broken bones in last 5 years	0.0	0.0	0.0	-0.1	0.0	-0.0	-0.0	0.0	-0.0	-0.0	0.1	0.1	0.1	0.1	0.1	0.0	-0.1	0.0	0.1	0.1	-0.1
Ever depressed for a whole week	0.0	0.0	0.1	-0.1	-0.0	0.3	-0.4	-0.1	-0.2	-0.1	-0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.0	-0.0	0.4	-0.1	0.1
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.1	-0.1	0.1	0.4	-0.1	-0.0	-0.0	-0.1	-0.1	-0.1	-0.0	-0.0	-0.1	-0.2	-0.2	0.2	-0.1	0.2
Pack years of smoking	0.0	0.0	0.2	-0.1	-0.2	-0.2	0.4	-0.2	-0.2	-0.0	-0.2	-0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-0.2	-0.0	-0.2	0.0

Hub : Genes

C7orf28B

Models

Trait associations