Hub : Genes

C7orf43

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Skin Not Sun Exposed Suprapubic 0.102 0.040 1.1e-04 0.120 NA 0.081 NA 0.100 4.3e-07 NA 3.2e-05 NA 4.0e-06
2 GTEx Whole Blood 0.091 0.031 4.9e-06 0.073 NA 0.061 NA 0.079 3.0e-07 NA 2.8e-06 NA 8.8e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.2 3.4 5.8 -2.4 1.1
Bipolar Disorder or Schizophrenia 1.5 3.7 6.2 -2.5 1.1
Depressed Affect (Nagel 2018) 0.0 0.1 0.2 -0.2 0.4
Depression (Nagel 2018) 1.3 2.0 2.9 -1.1 1.7
Intelligence (Savage-Jansen 2018) 0.7 2.2 4.5 -2.1 0.1
Neuroticism (Nagel 2018) 0.3 0.8 0.9 -0.8 1.0
Schizophrenia (2018) 0.5 1.0 1.5 -1.2 0.6
Schizophrenia vs Biploar Disorder 1.4 1.9 2.3 1.5 -1.2
Worry (Nagel 2018) 0.2 0.5 0.8 0.9 0.5
Alzheimer’s Disease (in mother) 8.6 10.1 17.4 4.2 -1.7
Alzheimer’s Disease (in father) 2.8 3.0 5.9 2.4 -0.2
Alzheimer’s Disease (including proxy) 13.5 19.6 32.7 5.7 -2.5
Crohns Disease (2017) 0.4 1.0 1.9 -1.4 -0.0
Irritable Bowel Disease (IBD) 1.3 3.1 4.4 -2.1 1.4
Ulcerative Colitis (UC) 1.2 2.3 2.5 -1.5 1.6
Major Depression (MDD) 1.2 1.5 2.9 -0.2 1.7
Reaction Time 0.4 0.7 1.3 -1.1 0.4
Verbal and Numeric Reasoning (VNR) 0.8 1.8 2.9 -1.7 -0.8
Breast Cancer 1.4 3.3 6.2 -2.5 0.7
Ovarian Cancer 0.0 0.1 0.1 -0.3 -0.1
Prostate Cancer 0.8 1.2 1.2 1.1 -1.1
Age at First Birth 0.3 0.4 0.7 0.2 0.8
Bipolar Disorder (2011) 2.2 2.2 2.6 -1.6 1.3
Body Mass Index (BMI) (2010) 0.7 1.0 1.4 -0.8 1.2
Coronary Artery Disease (CAD) 2.2 2.6 2.9 -1.7 1.5
Crohns Disease (2012) 0.4 0.6 1.3 0.1 -1.1
Mean Putamen Volume 3.0 3.4 6.0 -2.4 0.9
Fasting Glucose 0.1 0.1 0.2 -0.5 -0.1
HbA1C 0.7 0.8 1.5 1.2 0.2
HDL Cholesterol 0.1 0.1 0.1 0.3 0.3
LDL Cholesterol 1.6 2.5 3.2 -1.8 1.4
Lupus 0.5 0.7 1.4 -0.0 1.2
Neuroticism (2016) 1.6 2.3 3.2 -1.2 1.8
Primary Biliary Cirrhosis 0.4 0.6 0.7 -0.8 -0.7
Rheumatoid Arthritis 2.0 2.8 5.6 2.4 0.1
Schizophrenia (2014) 0.7 1.5 2.7 -1.6 0.6
Triglycerides 0.7 1.1 2.2 -1.5 -0.2
Type 2 Diabetes (T2D) (2012) 1.1 1.3 2.3 1.5 -0.5
Ulcerative Colitis 0.8 1.1 1.7 -0.7 1.3
Blood Eosinophil Count 0.2 1.5 3.1 -1.8 0.1
Blood Platelet Count 1.5 16.9 29.6 2.1 5.4
Blood Red Count 2.5 24.0 41.1 2.6 -6.4
Blood White Count 0.1 0.9 0.9 -0.9 1.0
Heel T-Score 0.1 1.2 2.2 0.3 -1.5
BMI 0.5 2.9 5.2 -0.8 2.3
Height 0.3 6.5 9.7 -3.1 1.8
Waist Hip Ratio (WHR) 0.5 2.3 4.4 -2.1 -0.5
Systolic Blood Pressure 0.3 1.5 2.9 -1.7 0.3
Smoking Status 0.6 1.4 2.7 -0.3 1.6
Allergy or Eczema 2.6 7.0 8.7 2.3 -3.0
Cardiovascular Disease 3.2 10.6 18.4 -4.3 1.6
Hypothyroidism (self reported) 0.9 2.1 3.0 1.1 -1.7
Respiratory disease 3.1 6.9 13.2 -0.8 -3.6
Type 2 Diabetes (T2D) (2018) 0.7 1.3 2.0 -1.4 -0.8
Lung FEV1/FVC ratio 4.4 22.4 29.6 5.4 3.9
Lung FVC 2.2 11.0 17.9 -4.2 2.0
Neuroticism 0.0 0.0 0.0 0.2 0.2
Chronotype (morning person) 0.1 0.1 0.2 0.1 0.5
Hair Pigment 0.1 2.3 4.0 2.0 -0.8
Tanning 0.1 1.2 2.3 0.5 1.5
Hand grip strength (left) 2.5 6.5 10.6 -3.3 1.5
Number of treatments/medications taken 0.5 0.9 1.2 -0.8 -1.1
Average weekly spirits intake 0.1 0.1 0.2 0.4 0.1
Sensitivity / hurt feelings 0.1 0.1 0.2 0.4 0.2
Frequency of depressed mood in last 2 weeks 0.3 0.5 0.8 -0.4 0.9
Hearing difficulty/problems: Yes 1.8 2.8 4.0 -2.0 1.2
Relative age of first facial hair 2.4 4.9 6.9 -1.7 2.6
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.4 0.3 -0.6
Ever used hormone-replacement therapy (HRT) 0.9 1.2 1.5 0.9 1.2
Ever had hysterectomy (womb removed) 0.8 0.9 1.5 1.2 -0.5
Systolic blood pressure, automated reading 0.2 0.5 0.9 -1.0 0.2
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.3 0.2 0.6
Angina 0.1 0.2 0.3 -0.1 -0.5
Medication for hormone replacement therapy 0.6 0.6 1.2 -0.2 1.1
Vitamin and mineral supplements 0.2 0.3 0.4 -0.6 0.3
Supplements: Zinc 0.6 0.7 1.4 -1.2 -0.1
Medication: Co-codamol 0.1 0.1 0.2 -0.3 0.5
Medication: Metformin 0.2 0.3 0.6 -0.8 -0.2
Diabetes (father) 0.3 0.3 0.5 0.4 -0.7
Diabetes (mother) 0.7 0.9 0.9 0.9 -1.0
Severe depression (siblings) 0.4 0.4 0.7 -0.8 0.3
Pack years adult smoking proportion 3.2 4.9 7.2 -2.7 1.6
Impedance of leg (right) 0.7 3.5 5.3 -2.3 -1.2
Leg fat-free mass (left) 0.4 1.9 3.7 0.1 1.9
Trunk fat percentage 1.0 4.1 6.0 -2.4 1.5
Hand grip strength (right) 2.5 6.7 11.7 -3.4 1.3
Townsend deprivation index at recruitment 2.8 4.0 4.6 -1.8 2.1
Current tobacco smoking 0.1 0.1 0.1 0.3 -0.4
Average weekly fortified wine intake 0.3 0.3 0.5 0.7 -0.4
Maternal smoking around birth 0.8 1.2 2.2 -0.4 1.5
Fed-up feelings 1.2 2.2 2.8 1.7 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 1.6 -0.1 1.3
Relative age voice broke 2.5 3.8 5.1 -1.6 2.3
Taking other prescription medications 0.2 0.3 0.5 0.1 -0.7
Age when periods started (menarche) 6.4 15.4 16.7 -3.8 4.1
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 3.6 1.9 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.3 0.4 -0.6
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 2.0 1.4 -1.2
Qualifications: CSEs or equivalent 1.3 1.7 2.1 1.2 -1.4
Serious illness, injury or assault to yourself 0.4 0.5 0.9 0.3 1.0
High blood pressure 4.0 11.3 19.2 -4.4 1.8
Hayfever, allergic rhinitis or eczema 2.1 4.6 4.8 2.1 -2.2
Multivitamins +/- minerals 0.2 0.3 0.5 0.7 0.3
Stomach or abdominal pain in last month 3.4 4.2 5.4 2.3 -1.7
Supplements: Glucosamine 1.1 1.5 1.6 1.3 -1.2
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 1.8 1.4 0.8
Medication: Atenolol 2.8 3.5 4.0 -2.0 1.7
Medication: Levothyroxine sodium 1.6 2.7 3.6 1.9 -1.4
Sitting height 0.3 2.3 4.0 2.0 -0.8
Chronic bronchitis/emphysema (father) 1.4 1.6 2.5 -1.6 0.8
High blood pressure (mother) 0.0 0.0 0.1 -0.1 -0.3
Body mass index (BMI) 0.6 2.5 4.5 -0.6 2.1
Impedance of leg (left) 1.0 4.8 7.2 -2.7 -1.6
Leg predicted mass (left) 0.4 1.9 3.8 0.0 2.0
Trunk fat mass 1.0 4.2 5.0 -2.2 1.8
Waist circumference 0.3 1.2 1.4 -1.0 1.2
Number of incorrect matches in round 0.8 1.3 1.4 -1.2 1.1
Past tobacco smoking 2.2 4.1 7.5 0.8 -2.7
Alcohol usually taken with meals 1.2 1.9 2.5 1.1 -1.6
Nervous feelings 0.0 0.1 0.1 0.3 -0.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.0 0.3 1.0
Hearing difficulty/problems with background noise 1.5 2.4 4.8 -2.2 -0.1
Hair/balding pattern: Pattern 2 1.8 2.2 3.8 -2.0 0.8
Had menopause 0.4 0.5 1.0 -0.1 1.0
Had other major operations 2.2 2.6 5.2 2.3 0.1
Forced vital capacity (FVC) 0.6 2.5 4.3 -2.1 0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 0.3 -0.6 -0.3
Ever unenthusiastic/disinterested for a whole week 1.3 1.5 2.3 0.9 1.5
Qualifications: None of the above 0.4 0.8 1.3 -0.5 1.1
Financial difficulties in last 2 years 0.3 0.4 0.7 0.2 -0.8
Mouth/teeth dental problems 1.7 2.6 4.8 -2.2 0.7
Heart attack 0.1 0.1 0.2 -0.1 -0.5
Allergy 3.0 7.0 9.9 -2.0 3.1
Pain all over the body in last month 1.6 1.7 3.4 0.1 1.8
Diabetes (self-reported) 0.5 0.8 1.1 -1.1 -0.7
Hayfever/allergic rhinitis (self-reported) 3.2 4.3 8.2 2.9 -0.6
Medication: Ramipril 0.4 0.5 0.9 -0.9 -0.3
Medication: Simvastatin 3.0 4.5 8.7 -3.0 0.5
Fluid intelligence score 0.5 1.1 1.5 -1.2 -0.8
Illnesses of siblings 3.1 4.4 8.7 3.0 -0.1
Neuroticism score 0.0 0.0 0.1 0.1 0.2
Weight 0.6 2.8 4.1 -1.2 2.0
Impedance of arm (right) 0.2 0.9 1.2 -1.1 -0.8
Arm fat percentage (right) 0.4 1.6 2.3 -1.0 1.5
Trunk fat-free mass 0.1 0.5 0.9 0.2 0.9
Hip circumference 0.2 0.8 1.7 -0.1 1.3
Time employed in main current job 0.3 0.3 0.5 -0.7 -0.4
Alcohol intake versus 10 years previously 0.1 0.1 0.2 0.2 0.5
Father’s age at death 1.6 2.2 4.3 2.1 0.2
Worrier / anxious feelings 0.0 0.0 0.1 -0.2 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 0.7 0.8 -0.2
Falls in the last year 1.4 1.8 2.3 1.2 1.5
Hair/balding pattern: Pattern 3 3.6 5.4 7.3 2.7 -1.9
Number of live births 0.8 1.2 1.9 -0.6 -1.4
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 2.6 0.3 1.6
Pulse rate 7.8 13.1 13.3 -3.6 3.6
Happiness 1.4 1.7 2.2 1.5 -1.1
Noisy workplace 0.4 0.5 0.7 0.8 0.6
Qualifications: A levels/AS levels or equivalent 0.1 0.3 0.3 0.6 -0.6
Serious illness, injury or assault of a close relative in last 2 years 7.4 8.5 9.5 2.7 -3.1
Mouth/teeth dental problems: Dentures 1.6 2.7 5.3 2.3 0.3
Asthma 1.6 3.2 5.4 -1.0 -2.3
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 0.9 0.5 -1.0
Medication: Cholesterol lowering 6.7 10.4 16.3 -4.0 2.1
Depression (self-reported) 1.7 2.0 4.0 0.1 2.0
Medication: Lansoprazole 0.2 0.2 0.3 0.4 -0.5
Prospective memory result 0.1 0.1 0.3 0.5 0.1
Lung cancer (father) 1.3 1.5 2.2 0.9 1.5
Illnesses of mother 1.0 1.3 1.4 1.2 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 2.2 0.6 1.5
Pulse wave Arterial Stiffness index 0.4 0.5 0.8 -0.9 0.4
Impedance of arm (left) 0.3 1.5 1.8 -1.4 -1.1
Arm fat mass (right) 0.5 2.2 3.4 -1.1 1.8
Trunk predicted mass 0.1 0.4 0.8 0.3 0.9
Standing height 0.1 0.9 1.8 -1.4 -0.2
Length of working week for main job 0.9 0.9 1.3 -1.2 0.7
Exposure to tobacco smoke at home 0.5 0.5 0.8 0.4 0.9
Breastfed as a baby 0.7 0.9 1.6 0.4 -1.3
Tense / ‘highly strung’ 0.7 1.2 2.3 -0.4 1.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 0.6 0.6 0.8
Hair/balding pattern: Pattern 4 0.3 0.7 1.0 1.0 -0.6
Birth weight of first child 1.0 1.8 3.6 -0.0 1.9
Peak expiratory flow (PEF) 1.0 2.4 2.4 1.6 1.5
Pulse wave reflection index 0.3 0.3 0.4 0.5 -0.6
Ever highly irritable/argumentative for 2 days 1.4 1.7 2.0 -1.2 1.4
Loud music exposure frequency 0.0 0.0 0.0 -0.2 -0.1
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 0.5 -0.6 0.7
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 1.6 1.3 -0.1
Blood clot in the leg (DVT) 1.3 1.7 3.4 1.8 -0.2
Medication: Paracetamol 0.0 0.1 0.1 -0.4 -0.1
Headache pain in last month 0.4 0.8 1.2 0.6 -1.1
Medication for cholesterol, blood pressure or diabetes 7.7 12.7 22.3 4.7 -1.8
Glaucoma (self-reported) 0.2 0.3 0.3 0.6 -0.5
Gout (self-reported) 0.9 1.2 2.0 -0.6 1.4
Hypothyroidism/myxoedema (self-reported) 0.9 1.8 2.1 1.2 -1.4
Medication: Amlodipine 2.0 2.8 4.3 -2.1 1.2
Medication: Ventolin 100micrograms inhaler 1.9 2.4 4.1 -2.0 -0.8
Birth weight 2.4 5.3 6.4 -2.0 2.5
Chronic bronchitis/emphysema (mother) 4.4 5.1 6.9 -2.6 1.8
High blood pressure (siblings) 1.1 1.6 2.6 -1.6 0.8
Forced vital capacity (FVC), Best measure 0.5 1.8 2.9 -1.7 0.8
Body fat percentage 1.1 4.4 5.9 -2.4 1.7
Leg fat percentage (right) 1.2 4.4 6.2 -2.5 1.6
Arm fat-free mass (right) 0.3 1.4 2.6 -0.4 1.6
Exposure to tobacco smoke outside home 2.4 3.3 6.0 -0.7 2.5
Comparative body size at age 10 0.2 0.5 1.0 -0.1 1.0
Number of full brothers 1.1 1.4 2.7 -0.3 -1.6
Worry too long after embarrassment 0.5 0.8 1.4 -1.2 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 3.3 -0.8 1.8
Wheeze or whistling in the chest in last year 0.1 0.1 0.2 -0.2 -0.4
Number of children fathered 1.7 1.9 3.3 1.8 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 2.5 2.9 3.8 -2.0 -1.4
Age at first live birth 0.8 1.3 1.6 1.0 -1.3
Pulse wave peak to peak time 0.4 0.4 0.7 0.8 -0.4
Health satisfaction 0.2 0.2 0.5 0.7 -0.1
Shortness of breath walking on level ground 0.2 0.2 0.4 -0.6 -0.1
Qualifications: College or University degree 0.1 0.4 0.7 -0.4 -0.8
Eye problems/disorders: None of the above 0.8 1.0 1.9 1.4 -0.2
Mouth/teeth dental problems: Loose teeth 0.4 0.5 0.9 -1.0 0.2
Emphysema/chronic bronchitis 1.4 1.6 2.7 -1.7 0.6
Medication for pain relief, constipation, heartburn 0.4 0.6 1.3 0.1 1.1
Neck or shoulder pain in last month 2.2 3.1 5.4 2.3 -0.9
Medication: Blood pressure 4.8 8.4 14.4 -3.8 1.6
Angina (self-reported) 0.1 0.1 0.2 0.0 -0.5
Migraine (self-reported) 0.4 0.5 0.5 0.7 -0.7
Medication: Ibuprofen 0.9 1.1 1.6 0.7 -1.3
Medication: Allopurinol 1.6 2.1 2.9 -1.1 1.7
Medication: Omeprazole 1.7 2.0 3.4 0.7 1.8
Medication: Seretide 50 evohaler 0.4 0.5 0.9 -1.0 -0.2
Mean time to correctly identify matches 0.6 1.1 2.0 -1.4 -0.4
Heart disease (mother) 1.1 1.4 2.0 -1.4 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.0 2.0 1.4 0.3
Whole body fat mass 1.0 4.0 4.2 -1.9 2.0
Leg fat mass (right) 0.9 3.6 3.8 -1.9 1.9
Arm predicted mass (right) 0.2 0.9 1.5 -0.6 1.2
Pulse rate, automated reading 11.3 36.5 37.5 -6.0 6.1
Alcohol intake frequency. 1.2 2.9 3.6 1.9 1.4
Comparative height size at age 10 0.1 0.4 0.5 0.6 -0.7
Number of full sisters 2.7 3.3 6.0 -2.5 0.8
Suffer from ‘nerves’ 0.3 0.5 0.6 0.5 0.8
Overall health rating 0.3 0.7 1.4 1.2 -0.1
Chest pain or discomfort 0.4 0.5 1.0 0.3 -1.0
Had major operations 0.9 1.1 1.5 1.2 -0.8
Age at last live birth 0.5 0.7 0.9 -0.7 -1.0
Family relationship satisfaction 0.1 0.1 0.2 -0.1 0.4
Leg pain on walking 6.1 7.7 8.9 2.5 -3.0
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 2.8 1.7 -0.0
Commuting to job workplace: Car/motor vehicle 1.3 1.5 2.9 1.7 -0.4
Illness, injury, bereavement, stress in last 2 years 3.0 3.6 5.7 -2.4 1.2
Medication: Aspirin 0.0 0.1 0.1 -0.2 -0.3
Supplements: Vitamin C 2.7 3.2 6.4 0.4 -2.5
Knee pain experienced in last month 1.8 2.8 5.6 2.4 -0.1
Hypertension (Self-reported) 4.6 12.7 21.2 -4.6 2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.4 2.8 4.9 2.2 -0.9
Illnesses of father: Heart disease 0.9 1.3 2.6 -1.6 0.2
Illnesses of siblings: Diabetes 1.9 2.3 3.0 1.3 -1.7
Smoking status: Previous 2.5 3.7 6.9 -0.7 2.6
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 0.3 -0.1 0.6
Whole body fat-free mass 0.2 1.0 2.0 0.1 1.4
Leg fat-free mass (right) 0.3 1.3 2.7 0.2 1.6
Arm fat percentage (left) 0.5 1.9 2.4 -1.2 1.5
Average weekly red wine intake 0.4 0.6 0.6 -0.8 0.8
Handedness (chirality/laterality): Left-handed 0.3 0.4 0.4 -0.6 0.6
Mood swings 0.3 0.5 1.0 -0.0 1.0
Loneliness, isolation 0.8 1.0 1.4 1.2 -0.8
Long-standing illness, disability or infirmity 1.5 2.4 3.5 1.1 -1.9
Ever had bowel cancer screening 0.9 1.0 1.5 -0.7 1.2
Diabetes diagnosed by doctor 0.4 0.7 1.0 -1.0 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.0 0.0 0.0 0.2 0.1
Friendships satisfaction 2.2 2.7 3.1 1.5 -1.8
Qualifications: nursing, teaching 0.1 0.2 0.4 -0.0 0.7
Commuting to job workplace: Walk 1.6 1.7 2.0 -1.2 1.4
Eye problems/disorders: Cataract 4.1 4.7 9.3 -3.0 0.4
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 1.8 0.7 -1.3
Medication for cholesterol 1.3 1.9 3.3 1.8 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 0.8 0.3 -0.9
Back pain experienced in last month 1.7 2.4 3.2 1.8 -1.3
Mineral and other dietary supplements 1.4 1.9 2.6 -1.6 1.1
Breast cancer (self-reported) 1.7 2.1 3.9 2.0 -0.5
Asthma (self-reported) 1.5 3.0 4.1 -1.3 -2.0
Osteoporosis (self-reported) 0.0 0.0 0.1 -0.1 0.2
Osteoarthritis (self-reported) 2.7 3.6 6.4 2.5 -0.8
Medication: Aspirin 0.0 0.1 0.1 0.2 -0.2
Medication: Gliclazide 0.6 0.7 1.1 1.1 -0.5
Illnesses of father: None of the above (group 1) 2.2 2.7 5.4 2.3 -0.1
Smoking status: Current 0.3 0.5 0.5 0.7 -0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.0 0.1 0.2 -0.1 0.4
Whole body water mass 0.2 1.0 2.0 0.2 1.4
Leg predicted mass (right) 0.2 1.3 2.6 0.2 1.6
Arm fat mass (left) 0.5 2.2 3.2 -1.1 1.8
Number of self-reported non-cancer illnesses 0.2 0.3 0.3 -0.6 0.5
Average weekly champagne plus white wine intake 0.1 0.1 0.2 0.5 0.2
Miserableness 0.1 0.1 0.2 -0.4 0.1
Guilty feelings 0.1 0.1 0.2 -0.1 0.4
Wears glasses or contact lenses 0.0 0.0 0.0 -0.2 -0.1
Ever taken oral contraceptive pill 1.6 1.8 3.5 0.4 -1.9
Hearing aid user 0.6 0.7 1.3 1.1 0.2
Mother’s age at death 2.8 3.6 4.5 2.1 -1.6
Financial situation satisfaction 0.6 0.8 0.8 0.9 -0.9
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.3 -1.1 -0.4
Commuting to job workplace: Public transport 0.4 0.4 0.8 -0.0 -0.9
Eye problems/disorders: Glaucoma 1.2 1.4 2.7 0.4 -1.6
Medication: Blood pressure 1.2 2.2 4.5 -2.1 -0.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.0 1.0 -0.9
Supplements: Fish oil (including cod liver oil) 0.6 0.7 1.4 1.2 -0.1
High cholesterol (Self-reported) 2.0 3.6 6.8 -2.6 0.6
Medication: Bendroflumethiazide 0.7 1.1 2.2 -1.5 -0.0
Medication: Paracetamol 0.1 0.1 0.1 0.3 -0.3
Medication: Lisinopril 3.2 4.1 6.5 -2.5 1.3
Medication: Atorvastatin 2.7 3.3 5.7 -2.4 1.0
Illnesses of father: High blood pressure 1.2 1.5 1.9 -1.0 1.4
Alcohol drinker status: Never 1.9 2.2 2.6 1.4 -1.6
Ever smoked 0.7 1.3 2.6 -0.2 1.6
Basal metabolic rate 0.2 1.3 2.6 -0.3 1.6
Leg fat percentage (left) 1.2 4.2 6.5 -2.5 1.4
Arm fat-free mass (left) 0.3 1.3 2.4 -0.5 1.6
Number of operations (self-reported) 1.1 1.7 3.0 1.7 0.6
Average weekly beer plus cider intake 1.3 1.9 3.5 -1.9 -0.6
Irritability 2.0 3.4 3.9 -2.0 1.7
Risk taking 0.3 0.4 0.4 0.7 -0.6
Ever had prostate specific antigen (PSA) test 0.4 0.4 0.8 -0.9 -0.2
Fractured/broken bones in last 5 years 0.6 0.7 1.3 1.1 0.5
Age started oral contraceptive pill 1.4 1.8 3.2 -1.8 -0.6
Diastolic blood pressure, automated reading 4.9 15.1 19.1 -4.4 3.3
Ever depressed for a whole week 0.3 0.3 0.6 0.3 0.8
Unable to work because of sickness or disability 1.6 2.0 3.9 0.5 2.0
Commuting to job workplace: Cycle 0.3 0.4 0.7 0.2 -0.8
Myopia 4.0 5.7 8.6 -1.7 2.9
Vascular/heart problems diagnosed by doctor 3.6 9.7 17.6 4.2 -1.4
Cholesterol lowering medication 2.5 3.7 6.5 -2.5 1.0
Medication: Omeprazole (e.g. Zanprol) 1.3 1.5 2.3 0.8 1.5
Pain experienced in last month 1.3 2.2 3.8 -1.9 0.7
Supplements: Calcium 0.4 0.5 0.8 0.9 0.4
Basal cell carcinoma (self-reported) 0.5 0.6 0.7 -0.8 -0.7
Heart attack/myocardial infarction (self-reported) 0.0 0.0 0.0 -0.2 -0.2
Deep venous thrombosis (DVT) (self-reported) 2.0 2.5 4.9 2.2 -0.4
Heart disease (siblings) 5.1 6.2 10.3 -3.2 1.4
Alcohol drinker status: Previous 0.8 1.0 1.9 -0.2 1.4
Pack years of smoking 4.3 6.3 8.3 -2.9 2.0
Impedance of whole body 0.6 3.0 4.6 -2.1 -1.2
Leg fat mass (left) 0.9 3.6 3.9 -2.0 1.8
Arm predicted mass (left) 0.2 1.0 2.0 -0.2 1.4