TWAS hub - C7orf49

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1230	0.0500	5.1e-03	0.076	NA	0.043	NA	0.052	8.9e-05	NA	2.9e-03	NA	1.0e-03
2	GTEx	Adrenal Gland	0.1902	0.0679	3.1e-03	0.055	NA	0.012	NA	0.043	4.9e-03	NA	1.2e-01	NA	1.2e-02
3	GTEx	Artery Coronary	0.2090	0.0770	2.4e-03	0.080	NA	0.163	NA	0.104	1.2e-03	NA	3.9e-06	NA	2.2e-04
4	GTEx	Cells EBV-transformed lymphocytes	0.4400	0.0790	4.0e-09	0.334	NA	0.300	NA	0.345	1.2e-11	NA	2.1e-10	NA	4.7e-12
5	GTEx	Colon Transverse	0.1500	0.0510	8.5e-04	0.069	NA	0.031	NA	0.045	3.3e-04	NA	1.2e-02	NA	3.2e-03
6	GTEx	Esophagus Mucosa	0.3730	0.0600	0.0e+00	0.203	NA	0.299	NA	0.324	1.2e-13	NA	2.4e-20	NA	3.2e-22
7	GTEx	Liver	0.2950	0.1050	1.9e-03	0.118	NA	0.188	NA	0.005	3.7e-04	NA	5.9e-06	NA	2.3e-01
8	GTEx	Pancreas	0.1310	0.0550	7.4e-03	0.092	NA	0.050	NA	0.064	1.1e-04	NA	3.5e-03	NA	1.1e-03
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1020	0.0390	2.6e-03	0.073	NA	0.046	NA	0.078	7.8e-05	NA	1.5e-03	NA	4.4e-05
10	GTEx	Skin Sun Exposed Lower leg	0.0620	0.0280	8.2e-03	-0.002	NA	-0.003	NA	-0.003	6.1e-01	NA	8.2e-01	NA	7.7e-01
11	METSIM	Adipose	0.0818	0.0240	5.1e-08	0.045	0.047	0.066	0.050	0.059	2.2e-07	1.3e-07	4.3e-10	5.8e-08	2.9e-09
12	ROSMAP	Brain Pre-frontal Cortex	0.0683	0.0229	4.6e-05	0.053	0.018	0.036	0.025	0.050	2.1e-07	1.7e-03	1.7e-05	3.0e-04	4.6e-07
13	TCGA	Cervical Squamous Cell Carcinoma	0.0610	0.0380	4.8e-03	0.044	0.047	0.032	NA	0.035	3.2e-03	2.2e-03	1.0e-02	NA	7.6e-03
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0362	0.0239	8.1e-04	0.016	0.021	0.012	NA	0.007	5.9e-03	1.7e-03	1.3e-02	NA	4.8e-02
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.1062	0.0531	1.6e-07	0.077	0.063	0.082	NA	0.079	5.3e-09	1.3e-07	1.5e-09	NA	3.0e-09
16	TCGA	Lung Adenocarcinoma	0.0478	0.0278	6.4e-06	0.021	0.027	0.034	NA	0.031	1.4e-03	3.6e-04	7.3e-05	NA	1.2e-04
17	TCGA	Pancreatic Adenocarcinoma	0.0650	0.0450	5.2e-03	0.001	0.043	0.008	NA	0.014	2.9e-01	6.9e-03	1.4e-01	NA	7.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Medication: Omeprazole (e.g. Zanprol)	5.6	6.8	12.2	1.9	2.6	2.7	2.5	3.4	3.2	2.9	2.5	2.7	-0.0	1.6	2.5	2.1	3.0	2.6	2.6	3.5
Commuting to job workplace: Cycle	5.3	6.4	11.5	2.9	1.7	1.8	2.9	3.4	2.6	1.7	2.5	1.5	1.8	3.2	3.1	2.3	2.5	3.1	2.6	2.5
Average weekly champagne plus white wine intake	4.2	5.8	9.7	-1.1	-0.9	-1.9	-3.0	-2.7	-3.1	-2.7	-3.0	-2.2	-1.7	-2.0	-1.9	-2.3	-2.7	-2.4	-2.7	-2.9
Medication: Omeprazole	3.5	4.1	9.1	1.6	1.5	1.8	1.8	3.0	2.6	2.1	1.8	2.4	-0.4	0.9	1.8	1.5	2.6	2.0	2.1	2.9
Other serious medical condition/disability diagnosed by doctor	3.4	4.5	9.3	2.4	2.7	0.5	1.9	3.0	2.3	2.1	1.9	1.7	0.5	1.6	2.6	1.7	2.2	2.5	1.9	2.4
Commuting to job workplace: Walk	3.4	3.7	8.0	1.4	1.4	1.2	2.1	2.6	2.3	1.2	2.4	1.6	0.3	1.4	2.0	1.9	2.1	2.3	2.8	2.1
Number of full brothers	3.2	4.0	8.2	1.1	0.6	2.0	2.5	2.6	2.7	1.7	2.2	1.9	0.4	1.8	1.7	1.6	2.5	2.0	2.9	2.3
Bipolar Disorder (2011)	3.1	3.0	7.2	1.5	0.5	0.7	2.4	2.0	1.7	2.2	2.4	-0.2	-0.6	1.6	1.9	2.7	1.6	2.1	1.3	1.7
Number of operations (self-reported)	2.9	4.3	8.2	2.5	1.4	0.6	2.3	2.9	2.0	2.0	2.2	0.7	-1.2	1.0	2.7	2.2	2.1	2.8	2.2	2.2
Bipolar Disorder (2018)	2.8	4.4	9.3	2.1	0.5	0.7	2.7	2.6	2.0	2.5	2.3	0.3	-0.5	1.9	2.4	2.4	2.2	2.6	3.0	2.0
Bipolar Disorder or Schizophrenia	2.6	6.3	11.6	2.2	1.1	0.8	2.9	3.0	2.4	3.4	2.6	0.5	-0.6	2.4	2.9	2.5	2.8	3.4	3.4	2.6
Schizophrenia (2014)	2.6	5.8	11.0	1.9	1.5	1.4	2.6	3.0	2.6	2.9	2.5	1.1	-0.0	2.2	2.7	2.3	2.8	3.3	3.1	2.7
Commuting to job workplace: Car/motor vehicle	2.6	3.0	5.9	-1.3	-2.4	-1.2	-1.5	-1.8	-2.1	-1.6	-1.6	-2.0	-1.4	-1.1	-1.7	-1.2	-1.6	-1.8	-2.4	-2.1
Birth weight of first child	2.5	4.6	9.2	0.9	-0.5	0.9	3.0	1.3	3.0	2.8	2.8	2.0	1.8	1.7	1.5	2.2	2.7	1.9	2.7	2.5
Illnesses of father: None of the above (group 1)	2.5	3.1	7.1	0.8	-0.2	2.7	1.8	0.9	2.2	1.4	1.9	1.9	1.7	2.6	1.0	1.6	2.2	1.0	1.9	2.2
Medication: Bendroflumethiazide	2.5	3.7	10.2	-3.2	-2.3	0.4	-1.6	-1.9	-1.7	-1.3	-1.2	-1.4	-1.3	-1.8	-3.0	-0.8	-2.0	-2.8	-2.0	-1.8
Blood Eosinophil Count	2.4	18.6	28.5	3.4	3.9	3.8	4.5	4.8	5.3	1.9	4.7	4.5	3.4	4.6	4.5	3.3	5.1	4.6	4.4	5.1
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	6.9	2.3	2.6	1.0	1.6	1.5	0.6	2.0	2.0	-0.9	-1.7	0.3	2.6	2.2	0.7	2.2	0.5	0.7
Pulse wave Arterial Stiffness index	2.4	2.8	5.7	2.0	1.4	1.8	1.2	1.9	1.6	0.4	1.6	1.9	0.7	1.7	1.9	1.1	2.4	1.6	2.0	2.1
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	5.2	1.4	2.3	1.9	1.5	0.9	1.2	2.1	1.9	0.8	1.4	2.3	1.7	1.7	1.4	1.1	0.4	1.5
Pulse wave peak to peak time	2.3	2.7	5.3	-2.0	-1.4	-2.2	-1.1	-2.0	-1.4	-0.4	-1.5	-1.9	-0.5	-1.5	-1.8	-1.1	-2.3	-1.4	-1.7	-2.0
Allergy or Eczema	2.2	5.7	15.4	2.6	3.9	-1.2	1.1	1.3	2.5	0.3	0.7	3.5	2.8	2.3	2.6	-0.2	2.8	2.8	2.9	2.9
Age at last live birth	2.2	3.2	5.9	-1.9	-1.4	-1.1	-2.2	-2.0	-1.6	-2.3	-2.2	-0.5	1.0	-0.7	-2.1	-2.3	-1.7	-1.9	-2.4	-1.7
Hypothyroidism (self reported)	2.1	4.9	8.9	1.5	0.9	1.7	2.6	2.6	2.8	2.1	2.6	2.5	0.8	1.7	1.9	2.2	2.9	1.9	2.2	3.0
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	6.4	1.6	1.0	0.1	1.1	1.8	2.0	1.3	1.0	2.1	0.9	1.4	1.6	0.6	2.5	1.7	1.9	2.2
Alcohol drinker status: Never	2.1	2.6	5.2	1.0	0.7	2.3	2.0	1.5	1.6	2.1	2.3	0.6	-1.7	0.0	1.3	2.3	1.4	1.2	1.3	1.7
Leg fat percentage (left)	2.1	7.5	17.3	1.8	2.1	4.0	3.6	3.3	2.8	3.8	4.2	0.7	0.8	1.8	2.5	4.2	1.7	2.1	0.7	2.4
Medication: Cholesterol lowering	2.0	3.1	6.4	-0.9	0.8	-2.3	-2.0	-1.8	-2.5	-1.8	-2.1	-1.8	-0.2	-1.4	-1.0	-1.9	-2.3	-1.1	-2.2	-2.0
Tinnitus: Yes, now most or all of the time	2.0	2.4	7.2	-1.7	-0.9	-2.0	-1.9	-1.1	-0.7	-2.2	-2.3	0.7	1.1	-1.5	-1.6	-2.7	-0.7	-1.0	-0.5	-0.9
Medication for cholesterol, blood pressure or diabetes	1.8	2.9	6.8	1.8	0.5	1.3	1.5	1.4	2.4	1.2	1.4	2.6	1.0	1.7	1.5	1.0	2.5	1.2	2.3	2.2
Rheumatoid Arthritis	1.7	2.4	7.1	-1.0	-0.4	-1.9	-2.1	-1.3	-0.8	-2.2	-2.4	1.1	2.1	-0.4	-1.4	-2.7	-0.6	-1.3	-0.7	-0.7
High blood pressure (mother)	1.7	2.4	4.8	-1.0	-0.5	-1.0	-1.7	-2.0	-2.1	-1.3	-1.4	-2.1	-1.2	-1.7	-1.1	-1.3	-2.2	-1.0	-1.5	-2.1
Leg fat percentage (right)	1.7	6.1	15.1	1.5	1.6	3.6	3.2	3.1	2.5	3.6	3.8	0.6	0.3	1.5	2.1	3.9	1.6	1.7	0.6	2.2
Wears glasses or contact lenses	1.7	1.9	5.7	1.6	1.8	2.4	1.3	1.7	1.1	0.7	1.0	0.5	0.6	1.4	1.6	1.4	1.2	1.2	1.2	1.5
HDL Cholesterol	1.6	2.6	8.0	-1.0	0.3	-2.0	-2.5	-2.0	-1.3	-1.5	-2.6	0.6	0.6	-0.9	-1.4	-2.8	-1.1	-1.6	-1.5	-1.2
Waist Hip Ratio (WHR)	1.6	7.1	14.8	2.6	2.5	2.6	3.1	3.4	2.1	3.9	3.0	0.7	1.4	2.9	3.2	2.5	2.5	3.1	1.5	2.6
Severe depression (siblings)	1.6	1.8	5.6	2.2	2.4	0.8	0.6	1.4	1.2	0.7	1.0	1.7	-0.5	0.8	1.9	0.6	1.6	1.3	0.4	1.5
Townsend deprivation index at recruitment	1.6	2.2	6.5	0.4	1.3	1.6	1.2	1.1	2.2	1.0	1.3	2.6	2.3	1.0	0.9	0.6	1.7	1.0	1.3	1.7
Hair/balding pattern: Pattern 2	1.6	2.0	3.9	1.0	1.4	1.5	1.2	2.0	1.7	1.8	1.3	1.8	0.6	0.5	1.1	1.0	1.7	1.0	1.5	2.0
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	6.7	0.7	0.2	1.0	1.8	1.9	2.6	2.3	2.0	1.8	0.9	0.8	1.1	1.8	1.9	1.3	1.5	2.0
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	6.1	0.9	0.9	1.6	2.1	2.3	2.4	1.5	1.9	2.3	0.4	0.7	1.4	1.4	2.4	1.7	1.9	2.5
Alcohol intake frequency.	1.6	3.8	6.2	1.6	1.1	2.5	2.1	2.5	1.9	1.9	2.2	1.0	0.4	2.2	1.8	2.2	2.1	1.9	1.9	2.3
Back pain experienced in last month	1.6	2.3	5.4	2.3	2.3	0.8	1.3	2.0	1.0	2.0	1.5	0.1	-0.9	1.0	2.2	1.8	1.0	1.7	0.4	1.3
Number of self-reported non-cancer illnesses	1.6	2.8	6.6	1.7	2.0	1.1	1.7	2.6	1.0	1.9	1.8	-0.5	-0.8	1.0	2.2	1.7	1.2	2.5	1.5	1.5
Medication: Co-codamol	1.5	1.7	2.9	1.5	1.2	0.7	1.1	1.6	1.4	1.6	1.2	0.8	1.4	1.7	1.6	1.0	1.3	1.6	0.8	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	6.4	-1.7	-2.0	-1.0	-0.9	-1.1	-0.9	-0.2	-0.5	-1.4	-2.2	-2.5	-1.5	-0.5	-1.2	-1.2	-1.2	-1.4
Number of live births	1.5	2.2	4.2	-1.9	-1.0	-1.3	-2.0	-2.0	-1.0	-1.4	-1.8	0.3	-0.3	-1.6	-2.0	-2.0	-0.8	-1.9	-0.9	-1.0
Systolic Blood Pressure	1.4	7.1	15.9	-0.9	-1.1	-1.9	-2.4	-2.1	-3.9	0.1	-2.0	-4.0	-3.5	-3.4	-1.4	-1.4	-3.6	-1.7	-3.4	-3.7
Cardiovascular Disease	1.4	4.7	14.2	-2.0	-1.8	0.0	-1.0	-1.6	-3.0	-0.2	-1.0	-3.8	-1.9	-2.4	-1.8	-0.7	-3.4	-1.6	-2.7	-3.2
Pack years adult smoking proportion	1.4	2.1	7.3	-0.0	-1.6	2.1	1.9	1.2	1.1	2.7	2.3	-0.6	-0.5	1.2	0.2	2.7	0.8	0.1	0.2	0.8
Loud music exposure frequency	1.4	1.6	3.5	-1.0	-0.2	-1.1	-1.8	-1.8	-1.0	-1.7	-1.8	0.0	1.1	-0.9	-1.1	-1.9	-1.1	-0.9	-0.6	-1.2
Miserableness	1.4	2.4	4.0	-1.2	-1.4	-1.2	-1.7	-1.8	-1.5	-1.8	-1.8	-1.1	0.2	-1.6	-1.5	-1.8	-1.8	-1.3	-2.0	-1.9
Lupus	1.3	2.0	4.8	-1.3	-1.6	-1.4	-1.5	-1.9	-1.3	-0.8	-1.5	-0.2	-0.8	-1.2	-1.9	-1.2	-1.0	-2.2	-1.6	-1.0
Ulcerative Colitis	1.3	1.9	4.6	-2.1	-1.8	-1.5	-1.2	-1.5	-0.2	-1.3	-1.9	0.7	1.2	-0.6	-2.0	-2.1	-0.6	-1.2	-0.2	-0.6
Had menopause	1.3	1.6	3.7	0.2	0.9	1.9	1.7	1.4	1.5	1.8	1.8	1.0	-0.3	0.3	0.6	1.6	1.1	0.6	1.1	1.6
Chest pain or discomfort	1.3	1.9	4.2	0.7	0.9	-0.3	0.8	1.5	2.0	0.6	0.7	1.9	1.6	2.0	1.1	0.5	1.8	1.5	1.8	1.8
Supplements: Fish oil (including cod liver oil)	1.3	1.6	5.1	1.3	0.6	0.9	1.8	0.9	1.3	2.3	1.5	0.6	1.0	1.5	1.2	1.8	1.1	0.7	0.8	1.2
Basal cell carcinoma (self-reported)	1.3	1.5	4.3	0.7	0.3	0.1	0.5	0.9	1.5	1.3	0.9	1.9	1.8	2.1	0.7	0.8	1.6	0.5	1.4	1.6
Pack years of smoking	1.3	1.9	7.3	0.3	-1.2	2.1	1.8	1.1	0.7	2.5	2.1	-0.9	-0.9	1.1	0.4	2.7	0.6	0.1	-0.1	0.6
Schizophrenia (2018)	1.2	2.5	5.7	1.2	1.0	0.5	1.5	1.8	1.4	2.3	1.5	0.3	-0.4	1.5	1.7	1.3	1.8	2.2	2.4	1.7
Reaction Time	1.2	2.3	4.3	1.2	0.5	1.0	1.5	1.9	1.6	1.6	1.7	1.2	0.8	1.4	1.6	1.3	1.9	1.7	2.1	1.7
Ovarian Cancer	1.2	1.6	3.2	-1.7	-1.5	-1.1	-1.2	-1.8	-1.0	-1.3	-1.2	-0.7	1.3	0.3	-1.7	-1.1	-1.3	-1.5	-0.6	-1.1
Neuroticism (2016)	1.2	1.7	5.3	-2.3	-1.8	0.6	-0.9	-2.0	-0.3	-1.1	-0.7	0.2	1.1	-0.9	-2.1	-0.8	-0.9	-2.0	-0.6	-0.7
Medication: Ibuprofen	1.2	1.4	7.5	-1.8	-2.7	-1.3	-0.9	-1.3	-0.2	-0.5	-1.2	0.0	-0.7	-1.3	-1.5	-1.2	-0.0	-0.9	0.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.8	-0.8	-0.6	-0.6	-1.3	-0.9	-1.4	-0.4	-0.8	-1.2	-0.6	-1.2	-1.2	-0.4	-1.8	-1.6	-2.0	-1.7
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	4.2	-1.3	-2.0	-0.0	-1.2	-1.5	-1.1	-2.0	-1.4	-0.7	-0.2	-1.3	-1.8	-0.9	-1.2	-2.0	-1.6	-1.3
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	5.1	0.3	1.7	1.2	0.9	0.7	1.4	2.2	1.2	1.4	1.8	1.2	0.7	1.0	0.9	0.5	0.8	1.3
Schizophrenia vs Biploar Disorder	1.1	1.5	3.5	-1.9	-0.5	-0.9	-1.5	-1.6	-0.9	-1.3	-1.6	-0.0	0.0	-1.3	-1.6	-1.8	-1.1	-1.2	-0.8	-1.0
Ulcerative Colitis (UC)	1.1	2.0	6.2	-2.5	-1.4	-1.0	-1.3	-2.0	-0.2	-0.6	-1.6	0.9	1.7	-0.2	-2.3	-1.9	-0.7	-1.7	-0.4	-0.6
Breast Cancer	1.1	2.7	6.9	1.6	2.6	1.9	1.4	1.8	2.0	0.7	1.1	2.3	0.3	0.5	1.9	0.8	1.8	1.8	1.6	1.9
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.5	0.2	0.4	1.6	0.9	1.3	1.6	1.9	1.4	1.7	-0.5	0.2	0.5	1.0	1.7	0.3	0.9	1.6
Medication: Levothyroxine sodium	1.1	1.8	4.7	0.2	1.0	2.2	1.7	1.3	1.7	1.5	1.6	1.6	0.8	0.8	0.8	1.3	1.4	0.8	0.8	1.7
Chronic bronchitis/emphysema (father)	1.1	1.3	9.2	0.0	0.3	0.9	0.2	1.2	-0.6	1.4	0.1	-1.8	-3.0	-2.0	0.2	0.4	-0.7	0.5	-0.4	-0.5
Waist circumference	1.1	4.1	11.2	0.4	0.8	3.0	2.7	2.1	2.4	2.8	3.3	0.8	1.8	1.7	1.2	3.1	1.2	0.9	-0.1	1.9
Had other major operations	1.1	1.3	2.8	0.6	0.6	1.2	1.4	1.5	0.8	1.4	1.7	-0.5	-1.6	-0.1	1.1	1.6	0.5	1.4	1.2	0.7
Pulse wave reflection index	1.1	1.3	4.2	2.0	0.4	0.2	0.5	1.2	0.7	-0.8	0.6	0.9	-0.2	1.3	1.7	0.5	1.8	1.5	1.8	1.1
Blood clot in the leg (DVT)	1.1	1.4	4.1	0.3	1.7	1.1	0.6	0.5	1.3	2.0	0.9	1.6	2.0	1.4	0.5	0.8	0.9	0.3	0.8	1.3
Body fat percentage	1.1	4.3	11.9	0.5	1.5	3.4	2.8	2.1	2.4	2.4	3.4	0.8	1.8	1.5	1.4	3.1	1.0	1.3	0.2	1.8
Mean time to correctly identify matches	1.1	2.1	4.2	1.0	1.0	1.4	1.3	1.7	1.7	0.8	1.6	1.5	0.4	1.4	1.4	1.2	2.0	1.3	2.0	1.9
Overall health rating	1.1	2.4	5.0	1.1	0.7	0.5	1.5	1.8	2.1	2.2	1.7	1.8	0.9	1.2	1.4	1.0	2.1	1.5	1.3	2.0
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.4	-1.6	-1.8	-0.4	-1.1	-0.9	-0.7	-1.7	-1.2	-0.5	-0.6	-1.4	-1.6	-1.2	-0.8	-1.1	-0.6	-0.8
Long-standing illness, disability or infirmity	1.1	1.7	2.9	1.1	1.5	-0.8	1.0	1.1	1.4	1.6	0.9	1.2	1.4	1.7	1.4	0.5	1.6	1.6	1.4	1.6
Friendships satisfaction	1.1	1.4	3.2	-1.3	-0.9	-0.6	-1.7	-1.7	-0.8	-1.8	-1.1	-0.1	0.1	-1.0	-1.4	-1.4	-0.8	-1.4	-1.0	-1.3
Eye problems/disorders: Cataract	1.1	1.2	3.0	1.1	0.8	1.4	1.5	0.8	1.1	0.9	1.7	0.4	0.0	1.3	1.2	1.7	1.2	0.8	0.4	1.0
Leg fat mass (left)	1.1	4.2	13.3	0.7	1.0	3.1	3.0	2.1	2.2	2.6	3.5	0.2	0.7	1.2	1.4	3.6	0.9	1.2	-0.0	1.6
Primary Biliary Cirrhosis	1.0	1.4	4.2	-0.0	-0.8	1.0	1.9	1.1	1.4	0.9	1.6	-0.2	0.4	0.4	0.8	1.4	0.7	1.9	2.0	0.8
Triglycerides	1.0	1.6	4.8	-0.6	-1.5	0.1	-0.6	-0.2	-1.5	-1.1	-0.2	-1.9	-1.6	-1.4	-1.0	0.4	-1.5	-1.3	-2.2	-1.5
Hayfever, allergic rhinitis or eczema	1.0	2.2	7.4	1.6	2.7	-1.7	0.1	0.3	1.3	-0.0	-0.1	2.2	1.7	0.9	1.6	-0.8	1.5	1.8	1.9	1.6
Birth weight	1.0	2.1	6.2	0.8	0.8	0.2	2.5	1.2	1.8	2.3	1.9	-0.0	0.5	0.4	1.4	2.2	0.4	2.1	1.1	1.1
Neck or shoulder pain in last month	1.0	1.4	2.9	1.1	1.2	0.5	1.4	1.4	1.6	1.3	0.6	1.3	1.2	0.6	1.3	0.3	1.2	1.7	0.9	1.3
Medication: Seretide 50 evohaler	1.0	1.2	5.0	-0.2	-0.1	2.2	1.0	0.8	1.1	1.4	1.4	0.3	0.2	1.3	0.4	1.5	1.0	0.3	1.5	1.1
Leg fat mass (right)	1.0	3.8	12.4	0.6	0.8	3.1	2.9	2.1	2.1	2.5	3.4	0.2	0.5	1.0	1.3	3.5	0.9	1.0	-0.1	1.6
Pulse rate, automated reading	1.0	3.1	12.1	1.8	1.7	1.6	1.8	2.7	0.7	3.5	1.9	-0.8	-0.7	0.5	2.1	2.0	0.6	2.3	0.7	1.0
Illnesses of father: Heart disease	1.0	1.4	4.3	-1.4	-0.8	-0.9	-0.9	-0.8	-1.1	-1.2	-0.8	-0.7	-1.4	-2.1	-1.4	-0.4	-1.3	-1.6	-1.6	-1.1
Breast cancer (self-reported)	1.0	1.2	2.2	0.9	0.6	1.0	1.5	0.9	1.4	0.8	1.5	0.5	0.8	1.5	1.1	1.5	1.1	1.1	0.7	1.0
Commuting to job workplace: Public transport	1.0	1.2	5.5	0.0	1.2	0.3	0.7	0.6	1.3	0.5	0.3	1.4	1.7	0.7	0.5	-0.2	1.0	1.1	2.3	1.4
Alzheimer’s Disease (including proxy)	0.9	1.4	2.7	-0.9	-1.4	-0.1	-0.9	-0.9	-1.5	-0.9	-1.0	-1.3	-1.6	-1.6	-1.1	-0.9	-1.3	-0.9	-1.0	-1.6
Lung FEV1/FVC ratio	0.9	4.6	28.5	-0.0	1.6	0.7	-1.5	-1.1	1.4	-1.4	-1.1	4.3	5.3	2.9	-0.5	-1.8	1.8	-0.9	0.8	1.6
Supplements: Zinc	0.9	0.9	2.6	0.0	-0.2	0.9	1.2	1.4	1.3	1.6	0.8	0.7	0.4	0.6	0.3	0.9	1.1	0.7	1.5	1.2
Medication: Metformin	0.9	1.3	3.0	0.1	1.2	0.9	1.1	0.9	1.5	-0.1	1.0	1.7	1.5	0.9	0.7	0.4	1.2	0.8	1.6	1.5
Trunk fat percentage	0.9	3.8	10.5	0.1	1.3	3.1	2.7	1.6	2.5	2.0	3.2	0.9	2.3	1.6	1.1	2.9	0.9	1.1	0.3	1.6
Mouth/teeth dental problems	0.9	1.5	8.0	-0.1	-1.2	0.2	0.8	0.4	1.0	2.8	0.9	0.5	1.4	2.0	0.2	0.7	1.0	0.6	2.0	0.7
Happiness	0.9	1.1	3.3	-1.2	-1.8	0.5	-0.6	-1.0	-0.8	-0.5	-0.3	-1.2	-0.5	-1.3	-1.2	-0.1	-1.1	-1.0	-1.3	-1.3
Lung cancer (father)	0.9	1.0	2.2	-1.5	-1.1	0.1	-1.1	-1.0	-0.9	-0.4	-0.7	-0.4	-0.5	-1.4	-1.5	-1.1	-0.9	-1.5	-1.0	-0.9
Illnesses of mother	0.9	1.1	3.6	1.9	1.5	-0.4	0.7	1.8	0.7	0.6	0.2	0.9	-0.8	0.2	1.5	0.5	1.2	1.1	0.6	1.2
Medication: Blood pressure	0.9	1.6	3.9	-2.0	-0.9	0.0	-1.0	-1.3	-1.6	-0.6	-0.8	-1.8	-0.4	-0.9	-1.6	-0.5	-1.7	-1.4	-1.7	-1.4
Smoking status: Previous	0.9	1.3	3.3	-1.2	-0.1	-1.1	-1.2	-1.8	-1.3	-1.3	-1.4	-0.6	0.6	-0.8	-1.1	-1.6	-1.2	-0.9	-0.8	-1.2
Medication: Gliclazide	0.9	1.0	4.8	0.5	0.5	0.4	0.8	0.8	1.1	-0.4	0.7	0.8	2.2	1.3	0.9	0.2	0.9	1.3	1.3	1.0
Body Mass Index (BMI) (2010)	0.8	1.0	4.0	-0.7	-0.8	2.0	1.2	0.6	0.6	1.2	1.6	-0.4	-1.1	-0.7	-0.3	1.9	-0.2	-0.4	-0.5	0.2
LDL Cholesterol	0.8	1.3	2.1	1.0	-0.3	1.5	0.9	1.3	1.4	0.8	0.7	1.5	1.2	1.3	0.8	0.7	1.5	0.9	1.4	1.3
Multivitamins +/- minerals	0.8	1.0	3.4	0.3	-0.5	0.6	1.1	0.8	1.4	1.8	1.2	0.8	1.3	1.1	0.5	1.2	0.9	0.5	0.9	0.7
Body mass index (BMI)	0.8	3.4	15.1	0.1	0.6	3.9	2.3	1.8	1.8	2.3	3.1	0.5	0.5	0.9	0.6	3.1	0.8	0.1	-0.6	1.4
Trunk fat mass	0.8	3.3	10.2	0.1	0.7	2.5	2.7	1.3	2.4	1.6	3.2	0.6	2.2	1.5	0.9	3.0	0.8	1.0	0.1	1.5
Alcohol usually taken with meals	0.8	1.3	3.8	0.2	0.2	-0.4	-1.5	-0.6	-1.4	-1.9	-1.6	-1.4	-1.6	-1.0	-0.3	-1.1	-1.2	-0.2	-0.4	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	5.7	-1.8	-2.4	-1.4	-0.8	-1.3	0.1	-0.7	-0.9	0.4	0.5	-1.0	-1.8	-0.8	-0.0	-1.5	-0.0	-0.3
Allergy	0.8	1.8	4.5	-1.5	-2.1	0.8	-0.5	-0.7	-1.3	-1.1	-0.6	-1.9	-1.5	-1.3	-1.5	-0.1	-1.6	-1.5	-1.6	-1.7
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	6.3	-0.8	0.9	-0.1	-0.5	-0.6	-0.6	-2.0	-0.5	-0.2	-0.8	-2.5	-0.5	-0.9	-1.1	-0.4	-1.4	-0.7
Whole body fat mass	0.8	3.4	10.7	0.3	0.9	2.8	2.8	1.7	2.2	2.0	3.3	0.4	1.4	1.3	1.1	3.2	0.8	1.0	-0.0	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	9.1	-0.7	0.7	0.8	-0.2	-0.9	0.7	-0.6	-0.4	1.4	3.0	0.8	-0.4	-0.9	-0.1	-0.2	0.6	0.2
Financial situation satisfaction	0.8	1.0	2.8	-1.2	-1.7	-0.4	-0.6	-0.3	-0.9	-0.8	-0.3	-1.3	-1.2	-0.8	-1.2	-0.1	-0.8	-1.2	-1.4	-1.2
Risk taking	0.8	1.2	3.3	-1.0	-1.8	-1.1	-1.0	-0.1	0.3	-0.9	-0.9	1.5	1.3	1.3	-1.3	-1.2	0.9	-1.3	0.2	0.5
Blood Red Count	0.7	6.9	33.4	0.2	0.4	-5.8	-2.9	-2.4	-0.1	-4.0	-3.1	3.4	3.3	1.1	-0.9	-4.1	1.2	-1.3	0.4	0.3
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.9	-2.2	-2.2	-0.3	-0.4	-0.9	0.7	0.1	-0.2	0.6	0.2	-1.3	-1.7	-0.6	-0.1	-1.1	-0.2	-0.3
Vitamin and mineral supplements	0.7	0.9	3.3	0.5	0.8	-0.2	-0.7	-0.5	-1.2	-1.6	-0.7	-0.9	-1.8	-1.4	0.1	-0.5	-1.0	-0.1	-1.1	-0.9
Stomach or abdominal pain in last month	0.7	0.9	2.3	-1.3	-1.2	0.4	-0.4	-1.5	-0.7	-0.2	-0.0	-1.0	-1.1	-1.3	-1.2	0.0	-0.9	-1.2	-0.5	-0.7
Qualifications: None of the above	0.7	1.6	4.3	-1.0	-1.0	0.9	-1.3	-1.3	-1.6	-0.2	-0.6	-1.2	-0.6	-0.9	-1.4	-0.4	-1.5	-2.0	-2.1	-1.6
Impedance of arm (right)	0.7	3.2	9.5	-0.8	0.3	-3.1	-2.1	-2.2	-0.8	-2.7	-2.6	0.7	2.8	0.3	-0.8	-3.1	-0.8	-0.2	0.2	-1.0
Alcohol intake versus 10 years previously	0.7	1.1	3.6	1.1	-0.3	0.9	1.1	1.7	0.7	1.9	1.4	0.1	0.9	1.1	1.0	1.3	0.7	0.9	0.4	0.5
Worrier / anxious feelings	0.7	1.3	4.4	1.2	0.5	0.1	1.0	0.3	1.4	0.9	0.7	1.8	2.1	1.0	1.0	0.3	1.5	0.9	0.9	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	7.5	-1.0	-2.7	-0.7	-0.7	-1.0	-0.1	-0.3	-1.0	0.3	-0.7	-0.4	-1.2	-0.8	0.7	-1.1	0.4	-0.1
Medication: Lansoprazole	0.7	0.8	2.8	0.9	1.7	1.5	0.9	1.1	-0.2	0.2	0.9	-0.6	-1.4	-0.1	1.0	1.0	-0.1	0.7	-0.4	0.1
Breastfed as a baby	0.7	0.9	2.3	1.1	0.8	0.6	0.8	1.5	0.8	1.0	1.0	1.1	-0.0	0.8	0.8	1.0	1.3	0.3	0.4	1.4
Glaucoma (self-reported)	0.7	0.8	2.5	-0.6	-0.1	-0.7	-1.0	-1.2	-0.5	-1.5	-0.9	0.3	1.6	0.9	-0.8	-1.1	-0.3	-0.8	-0.7	-0.3
Comparative body size at age 10	0.7	2.0	6.7	1.4	0.6	2.4	1.6	1.4	0.1	1.6	1.9	-1.7	-1.2	0.7	1.5	2.6	-0.1	1.0	-0.0	-0.0
Number of children fathered	0.7	0.7	2.0	-0.5	0.1	-0.5	-0.7	-0.0	-1.0	-1.1	-0.7	-1.1	-0.9	-1.2	-0.4	-0.6	-1.4	-0.3	-1.3	-1.1
Shortness of breath walking on level ground	0.7	0.8	3.2	-1.4	-1.5	-0.3	-0.6	-0.3	0.4	-0.0	-0.5	1.1	1.8	-0.0	-1.3	-0.9	0.1	-1.1	-0.3	0.1
Suffer from ‘nerves’	0.7	1.1	4.6	-0.3	-1.9	-1.1	0.1	0.1	1.2	-0.5	-0.6	2.1	1.1	-0.0	-0.5	-1.1	1.7	-0.2	1.1	1.0
Hypertension (Self-reported)	0.7	1.8	6.4	-1.4	-1.0	1.3	0.2	-0.3	-1.5	0.7	0.4	-2.5	-1.6	-1.3	-1.1	0.8	-1.9	-1.1	-1.8	-1.5
Loneliness, isolation	0.7	1.0	2.7	0.5	-0.9	-0.0	0.8	0.8	1.6	0.8	0.9	1.1	0.3	0.9	0.6	0.8	1.6	0.9	1.4	1.3
Hearing aid user	0.7	0.7	1.4	-0.5	0.7	-0.9	-0.9	-0.3	-1.2	-1.1	-0.9	-0.4	-0.7	-1.1	-0.5	-1.2	-1.0	-0.7	-0.9	-1.0
Ever smoked	0.7	1.1	7.3	0.6	1.1	-0.0	0.2	0.3	1.0	-1.2	-0.4	2.0	2.7	0.5	0.6	-1.1	0.9	0.7	0.3	0.9
Average weekly beer plus cider intake	0.7	1.0	2.7	-1.0	-1.6	-0.5	-0.4	-1.4	-0.8	-1.0	-0.6	-0.4	-0.4	-1.4	-1.1	-0.8	-0.8	-1.1	-1.3	-1.3
Irritability	0.7	1.3	4.8	0.8	-0.1	0.1	0.8	0.9	1.6	1.0	0.5	2.2	1.2	0.7	0.5	0.3	1.9	0.5	1.3	1.7
Pain experienced in last month	0.7	1.2	2.6	-1.6	-0.8	0.0	-1.1	-1.4	-0.9	-1.4	-0.9	-0.3	0.3	-0.7	-1.6	-0.9	-1.2	-1.6	-1.0	-1.2
Intelligence (Savage-Jansen 2018)	0.6	1.8	4.2	1.2	1.7	0.6	1.2	1.0	1.5	0.1	1.0	2.0	0.7	1.3	1.2	0.7	1.9	1.1	1.4	2.0
Average weekly spirits intake	0.6	0.7	3.5	0.9	1.9	-1.1	-0.9	0.1	-0.5	-1.3	-1.2	0.2	0.2	0.0	0.7	-1.2	0.1	0.4	0.3	0.0
Medication for hormone replacement therapy	0.6	0.6	2.6	-0.4	0.3	0.8	0.0	0.3	1.2	0.7	0.4	1.6	-0.8	-0.3	-0.0	-0.1	1.1	0.2	1.0	1.2
Current tobacco smoking	0.6	0.9	2.0	0.4	-0.3	1.1	1.4	1.3	1.2	1.4	1.3	0.7	0.9	0.7	0.7	1.1	0.9	0.7	0.3	1.0
Relative age voice broke	0.6	0.9	3.7	0.5	0.7	-1.1	-1.5	-0.9	-1.0	-1.7	-1.9	0.1	-0.3	-0.3	-0.2	-1.6	-0.3	-0.5	-0.4	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.1	1.2	0.6	1.4	1.1	2.0	1.4	0.2	1.0	1.3	-0.2	1.2	1.0	1.3	1.5	0.6	1.3	1.4
Medication: Atenolol	0.6	0.8	2.6	-1.0	0.9	0.0	-0.8	-0.9	-0.9	-0.2	-1.0	-0.3	-0.5	-1.6	-0.8	-1.0	-1.2	-0.8	-0.8	-0.7
Diabetes (self-reported)	0.6	0.9	4.1	-0.4	1.1	0.8	0.4	0.0	1.4	-0.2	0.3	2.0	1.6	0.2	0.2	-0.6	0.9	0.5	1.1	1.1
Time employed in main current job	0.6	0.7	4.2	-0.0	0.1	1.5	0.3	0.7	-0.4	-0.1	0.4	-1.2	-2.0	-1.0	0.1	0.9	-0.6	0.1	-0.4	-0.3
Falls in the last year	0.6	0.8	2.8	-0.1	0.6	0.9	1.0	0.6	1.1	1.1	1.0	0.3	1.7	1.4	0.4	1.1	0.5	0.7	0.7	0.9
Length of working week for main job	0.6	0.7	1.8	-0.9	-1.3	1.3	0.9	0.6	0.3	0.7	1.0	-0.4	-0.2	1.0	-0.7	1.3	-0.0	-0.6	0.0	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.9	-0.7	-2.2	0.7	0.3	-0.2	1.0	1.3	0.5	0.9	0.1	0.1	-0.8	0.7	0.9	-0.8	0.4	0.5
Age at first live birth	0.6	1.1	2.8	-1.7	-0.5	-0.5	-1.0	-1.6	-0.9	-0.5	-0.9	-0.5	1.3	0.0	-1.3	-1.2	-1.0	-1.1	-1.2	-0.9
Medication: Allopurinol	0.6	0.8	3.5	1.4	0.8	-0.1	0.1	0.3	-1.2	-0.7	-0.1	-1.9	-0.5	-0.3	1.1	0.0	-0.7	1.1	-0.8	-0.9
Arm fat percentage (left)	0.6	2.6	11.2	-0.4	0.9	3.3	1.8	1.1	2.1	1.3	2.5	1.3	2.3	1.2	0.3	2.2	0.6	0.1	-0.3	1.3
Osteoporosis (self-reported)	0.6	0.7	3.3	0.8	0.8	1.3	0.3	-0.1	0.8	0.1	0.5	1.3	1.8	1.2	0.6	0.3	0.9	0.2	0.5	0.9
Arm fat mass (left)	0.6	2.4	8.7	-0.4	0.3	2.9	2.1	1.0	1.9	1.4	2.8	0.6	1.5	0.9	0.3	2.7	0.5	0.1	-0.5	1.1
High cholesterol (Self-reported)	0.6	1.0	3.7	-0.5	0.5	-0.6	-0.3	-0.4	-1.6	-0.2	-0.5	-1.9	-1.2	-1.2	-0.3	-0.3	-1.5	-0.2	-1.7	-1.4
Medication: Lisinopril	0.6	0.8	6.2	0.0	0.8	0.0	-0.8	-0.3	-0.9	-0.5	-0.7	-1.1	-2.5	-1.5	0.1	-0.4	-0.7	0.1	-0.3	-0.7
Vascular/heart problems diagnosed by doctor	0.6	1.5	4.8	1.3	0.7	-0.6	0.2	0.1	1.4	-0.3	-0.1	2.2	1.3	1.4	1.0	-0.3	1.9	1.0	2.2	1.5
Crohns Disease (2017)	0.5	1.0	2.7	-0.2	1.3	-0.8	-1.1	-1.1	-1.2	-1.2	-1.5	-0.6	-0.3	-1.2	-0.2	-1.6	-1.1	-0.0	-0.6	-1.1
Irritable Bowel Disease (IBD)	0.5	1.2	3.5	-1.6	0.1	-1.0	-1.3	-1.8	-0.6	-0.8	-1.6	0.3	0.9	-0.6	-1.4	-1.9	-0.8	-0.9	-0.4	-0.7
Coronary Artery Disease (CAD)	0.5	0.6	1.7	0.1	1.3	0.6	1.0	0.3	0.9	0.9	1.3	0.5	0.1	0.2	0.6	0.8	0.7	0.8	0.8	0.9
Crohns Disease (2012)	0.5	0.8	2.3	0.6	1.0	-0.1	1.1	0.8	1.1	0.2	0.4	0.8	0.6	0.4	1.0	0.2	0.8	1.5	1.5	0.9
Fasting Glucose	0.5	0.6	1.6	-1.3	-0.8	0.9	0.1	-0.0	-0.4	0.9	0.2	-1.1	-0.8	-1.1	-0.7	0.5	-1.0	-0.3	-0.3	-0.6
Blood Platelet Count	0.5	6.1	11.8	-2.2	-1.0	-1.2	-3.4	-2.5	-3.1	-2.9	-3.4	-1.7	-0.8	-1.8	-2.5	-3.4	-2.5	-2.4	-2.4	-2.7
BMI	0.5	2.9	8.5	0.3	1.0	2.9	2.2	1.4	1.9	2.6	2.7	0.7	0.4	1.1	0.8	2.8	1.0	0.5	0.2	1.7
Relative age of first facial hair	0.5	1.0	4.3	1.0	1.1	-1.0	-1.1	0.0	-0.7	-2.1	-1.9	0.3	0.3	-0.3	0.4	-1.7	-0.2	0.4	-0.3	-0.4
Systolic blood pressure, automated reading	0.5	1.5	6.8	-0.3	-0.0	-1.0	-0.8	-0.9	-1.7	0.6	-0.7	-1.4	-2.6	-1.7	-0.6	-0.2	-1.2	-1.2	-2.0	-1.1
Angina	0.5	0.6	4.2	-0.1	0.2	-2.1	-1.0	-0.4	-0.4	-1.2	-1.1	0.1	0.3	-0.2	-0.2	-1.2	-0.3	-0.2	-0.3	-0.3
Diabetes (mother)	0.5	0.6	4.5	-0.6	-1.1	-0.2	0.4	-0.8	0.6	-0.0	0.5	0.9	2.1	0.9	-0.5	-0.1	0.8	-0.4	0.3	0.2
Fed-up feelings	0.5	0.9	2.5	-1.2	-1.6	-0.8	-1.0	-1.1	-0.2	-0.3	-1.0	0.0	0.6	-1.1	-1.3	-1.1	-0.6	-1.0	-0.9	-0.8
Age when periods started (menarche)	0.5	1.1	2.5	1.3	0.8	0.3	0.9	1.2	0.8	0.6	0.8	0.8	-1.6	0.2	1.2	0.8	1.6	0.8	1.5	1.4
High blood pressure	0.5	1.5	4.5	-1.3	-1.1	1.0	0.1	-0.2	-1.3	0.8	0.3	-2.1	-1.5	-1.4	-1.0	0.6	-1.7	-1.1	-1.8	-1.4
Impedance of leg (left)	0.5	2.3	9.3	2.0	1.6	-0.6	1.4	2.0	0.8	1.6	0.8	-0.2	0.0	0.8	2.4	0.6	1.1	3.1	2.2	0.9
Number of incorrect matches in round	0.5	0.9	4.5	-0.5	-0.2	2.1	0.8	0.5	-0.2	1.9	1.1	-1.1	-0.9	-0.2	-0.1	1.3	-0.3	-0.1	-0.0	0.1
Fluid intelligence score	0.5	1.1	2.7	1.5	1.2	0.1	0.6	0.4	0.9	-0.6	0.1	1.1	1.2	1.2	1.4	-0.1	1.3	1.6	1.3	1.2
Depression (self-reported)	0.5	0.7	2.4	0.1	-1.4	1.5	0.9	0.8	0.7	1.1	0.9	0.3	-0.5	0.3	0.0	0.9	1.0	-0.0	0.2	0.6
Impedance of arm (left)	0.5	2.1	8.8	-0.6	0.1	-2.4	-1.4	-1.6	-0.0	-2.0	-1.8	1.3	3.0	0.6	-0.5	-2.5	-0.1	0.2	0.8	-0.4
Tense / ‘highly strung’	0.5	0.9	5.3	-1.7	-2.3	-0.4	-0.4	-0.9	0.2	-0.1	-0.6	0.6	0.0	-0.3	-1.6	-0.8	0.3	-1.1	0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.9	0.6	0.5	-1.3	-1.2	0.0	-1.0	-0.9	-1.0	-0.6	-1.7	-1.1	0.4	-1.1	-0.4	0.4	-0.1	-0.6
Headache pain in last month	0.5	0.8	5.1	-0.3	-0.9	2.3	0.8	0.2	0.9	0.3	0.8	0.7	1.0	1.0	-0.1	0.7	0.7	0.1	1.0	0.9
Gout (self-reported)	0.5	0.6	2.3	1.4	1.1	-0.1	-0.1	-0.2	-1.0	-0.8	-0.1	-1.5	-0.5	-0.4	1.1	0.0	-0.7	0.9	-0.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.6	-0.6	0.5	0.3	0.3	-0.3	1.1	1.3	0.7	1.1	1.2	1.0	-0.0	0.3	0.7	0.0	1.0	0.8
Health satisfaction	0.5	0.7	2.5	-0.6	-0.2	-1.6	-1.1	-0.8	-0.3	0.2	-1.1	0.2	1.4	-0.2	-0.7	-1.3	-0.7	-0.4	-0.4	-0.6
Angina (self-reported)	0.5	0.7	4.6	-0.0	0.3	-2.1	-1.0	-0.5	-0.5	-1.2	-1.2	-0.0	0.1	-0.3	-0.2	-1.3	-0.3	-0.1	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	6.0	-0.9	-1.0	-2.4	-0.3	-1.2	-0.1	-1.5	-0.2	-0.6	1.8	0.1	-0.4	-0.6	-0.9	0.3	-0.2	-0.9
Qualifications: nursing, teaching	0.5	0.8	1.9	1.3	1.2	1.3	0.7	1.2	0.2	0.2	0.7	-0.3	-0.8	0.3	1.4	0.8	0.5	1.2	0.8	0.6
Medication for cholesterol	0.5	0.7	3.2	1.3	1.0	-1.8	-0.4	-0.2	-1.1	-1.2	-1.0	-0.9	-0.3	0.5	0.8	-0.6	-0.0	0.5	0.2	-0.3
Mineral and other dietary supplements	0.5	0.7	2.6	-0.9	-0.8	-0.6	-0.9	-0.5	-0.9	-1.6	-0.6	-0.7	-0.9	-0.6	-0.9	-0.7	-0.5	-0.7	-0.8	-0.7
Medication: Aspirin	0.5	0.6	1.9	-1.4	0.2	-0.4	-0.7	-1.1	-0.2	-1.2	-0.6	0.6	0.7	-0.4	-1.0	-1.2	-0.4	-0.8	-0.5	-0.3
Smoking status: Current	0.5	0.7	1.5	0.5	-0.3	0.8	1.1	1.2	1.1	1.1	0.9	0.8	1.2	0.7	0.7	0.7	0.9	0.7	0.2	0.9
Ever taken oral contraceptive pill	0.5	0.5	3.9	0.1	-0.7	-2.0	-0.5	0.6	-0.8	-0.3	-1.0	-0.9	-0.5	-0.1	0.0	-0.7	-0.5	0.4	-0.0	-0.7
Illnesses of father: High blood pressure	0.5	0.6	3.5	-0.3	-0.5	-1.9	-0.3	-0.7	-0.9	-0.3	-0.4	-1.4	-0.5	-0.8	-0.2	-0.2	-0.9	-0.1	-0.6	-1.1
Fractured/broken bones in last 5 years	0.5	0.7	2.5	-1.1	-1.6	-0.7	-0.6	-1.2	0.3	-0.5	-0.6	0.8	0.7	-0.5	-1.2	-0.6	0.2	-1.0	0.2	0.0
Ever depressed for a whole week	0.5	0.6	2.1	0.8	0.1	-0.7	0.6	0.7	0.9	0.5	0.3	1.0	0.3	0.8	0.7	0.5	1.5	0.6	1.2	1.0
Cholesterol lowering medication	0.5	0.8	3.4	-0.4	0.1	1.5	1.2	0.7	1.0	1.9	1.5	0.3	0.1	-0.4	0.3	1.1	0.2	0.5	-0.0	0.3
Prostate Cancer	0.4	0.6	1.2	0.0	-0.7	-0.6	-0.7	-0.3	-1.1	-0.5	-1.1	-0.9	-1.1	-0.9	-0.5	-0.6	-0.8	-0.7	-0.7	-1.1
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.2	0.0	0.4	1.0	0.9	0.9	1.1	0.9	0.8	0.3	0.5	0.5	0.4	0.8	0.3	0.7	1.0	0.6
Lung FVC	0.4	2.0	9.2	1.2	0.3	0.8	1.8	1.0	0.3	0.9	1.9	-1.6	-3.0	-0.5	1.4	2.7	0.1	1.1	0.7	0.3
Chronotype (morning person)	0.4	0.9	5.1	0.5	-0.3	0.1	0.1	0.4	-1.4	-1.0	-0.4	-2.3	-2.0	-0.8	0.4	0.0	-0.9	0.6	-0.1	-0.9
Number of treatments/medications taken	0.4	0.7	2.9	0.1	0.1	0.7	0.7	0.7	0.7	1.7	0.5	0.4	0.6	0.8	0.6	0.2	1.1	1.1	1.4	0.9
Ever had hysterectomy (womb removed)	0.4	0.4	1.5	0.3	-0.5	0.6	0.6	0.5	0.6	0.4	0.8	1.2	-0.3	0.2	0.0	0.5	1.2	-0.4	0.3	0.9
Diabetes (father)	0.4	0.5	1.6	0.9	1.3	-1.3	-0.7	0.0	0.0	-0.7	-0.5	0.8	1.2	1.0	0.4	-0.6	0.4	0.0	-0.3	0.3
Impedance of leg (right)	0.4	1.8	7.2	1.7	1.2	-1.0	1.1	1.7	0.6	1.4	0.4	-0.2	-0.5	0.5	2.1	0.3	1.1	2.7	2.1	0.8
Average weekly fortified wine intake	0.4	0.5	2.6	0.9	0.6	0.0	0.1	0.3	-1.0	-0.8	-0.1	-1.6	-1.3	0.0	0.7	0.2	-0.5	0.7	0.1	-0.5
Taking other prescription medications	0.4	0.6	1.4	0.6	1.0	0.0	0.7	1.0	0.8	0.8	0.6	0.7	0.3	0.7	0.9	0.2	1.0	1.1	1.0	1.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.8	-0.9	-1.0	1.0	-0.5	-0.1	-0.5	0.1	-0.4	-0.4	-1.3	-0.8	-1.0	-0.3	-0.2	-1.0	-0.1	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.7	0.9	1.6	-0.9	0.0	0.2	0.4	0.3	-0.2	1.1	-0.3	-0.1	0.9	-0.7	0.8	1.0	0.7	0.8
Medication: Ramipril	0.4	0.5	2.1	-1.5	-0.4	0.2	0.1	-1.1	-0.4	-0.0	0.3	-0.9	0.6	-0.6	-0.8	0.1	-1.2	-0.6	-0.7	-0.9
Medication: Simvastatin	0.4	0.5	1.8	-0.5	1.4	-0.4	-0.6	-0.7	-0.9	0.2	-0.3	-0.8	0.1	-0.5	-0.2	-0.5	-1.1	-0.3	-1.2	-0.9
Weight	0.4	2.0	8.0	-0.3	-0.6	1.5	2.4	0.9	1.9	1.2	2.8	0.2	1.2	1.0	0.4	2.8	0.5	0.4	-0.2	1.1
Arm fat percentage (right)	0.4	1.7	8.1	-0.5	0.7	2.9	1.3	0.7	1.6	0.8	1.9	1.0	2.1	0.9	0.0	1.7	0.3	-0.2	-0.7	0.9
Father’s age at death	0.4	0.6	3.0	-0.0	1.7	0.3	-1.1	-1.2	-0.3	-0.7	-0.9	0.8	0.5	0.2	-0.1	-1.0	0.1	-0.4	0.3	0.3
Pulse rate	0.4	0.6	2.4	-1.6	-0.5	0.5	0.0	-0.5	-0.4	0.8	0.3	-0.8	-0.1	-1.1	-1.0	0.1	-1.2	-0.5	-1.2	-0.8
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.0	-0.3	-0.1	-1.3	-1.2	-0.8	-0.9	-2.0	-1.5	-0.7	-0.2	-0.5	-0.3	-1.4	-0.6	0.0	0.5	-0.8
Mouth/teeth dental problems: Dentures	0.4	0.7	2.8	0.6	1.4	0.1	-0.5	0.4	-0.8	-1.7	-0.2	-0.7	-1.5	-0.9	0.4	-0.1	-0.8	0.1	-1.3	-0.6
Arm fat mass (right)	0.4	1.7	6.8	-0.6	0.1	2.6	1.7	0.7	1.6	1.0	2.3	0.5	1.5	0.6	0.0	2.3	0.3	-0.1	-0.7	0.9
Peak expiratory flow (PEF)	0.4	0.9	4.7	-0.3	-0.5	-0.6	-1.0	-1.7	0.0	-1.6	-0.8	1.0	2.2	0.3	-0.7	-0.8	-0.1	-0.9	-0.1	-0.3
Medication: Amlodipine	0.4	0.6	6.5	-1.0	-0.1	0.4	0.2	-0.9	0.4	0.1	0.3	0.5	2.6	0.9	-0.5	-0.1	-0.2	-0.2	0.6	-0.0
High blood pressure (siblings)	0.4	0.6	2.5	0.3	0.8	0.8	1.1	0.4	-0.1	1.3	1.4	-0.9	-0.2	0.7	0.6	1.6	-0.0	0.4	0.1	0.4
Exposure to tobacco smoke outside home	0.4	0.6	2.4	0.5	-0.7	0.9	0.6	0.9	-0.1	0.9	0.5	-1.0	-1.6	-0.5	0.3	1.2	-0.3	0.1	-0.2	-0.2
Wheeze or whistling in the chest in last year	0.4	0.8	3.4	-0.8	-1.5	0.7	0.7	-0.1	0.1	1.8	1.3	-0.7	0.8	0.6	-0.5	1.1	-0.2	-0.7	-0.9	-0.3
Emphysema/chronic bronchitis	0.4	0.4	1.1	-0.9	-0.6	0.9	0.1	0.6	0.1	1.0	0.5	-0.3	-1.0	-0.8	-0.7	0.5	-0.3	-0.6	-0.2	0.0
Migraine (self-reported)	0.4	0.5	1.7	0.7	1.0	1.3	0.1	0.3	0.1	-0.2	0.0	0.6	1.3	0.9	0.7	-0.3	0.5	0.7	0.9	0.5
Heart disease (mother)	0.4	0.5	2.9	-0.4	0.8	0.7	0.1	-0.4	0.9	0.1	0.6	1.4	1.7	0.6	-0.0	0.1	0.3	-0.2	-0.2	0.5
Number of full sisters	0.4	0.4	2.1	-0.8	-0.1	1.4	-0.1	-0.2	0.3	0.1	0.3	1.1	0.7	-0.3	-0.8	-0.2	0.0	-0.9	-1.1	0.1
Leg pain on walking	0.4	0.5	1.8	-1.2	-1.4	-0.3	-0.2	-0.7	0.2	0.9	-0.0	0.7	0.7	0.0	-1.0	-0.4	0.3	-0.9	-0.3	-0.1
Medication: Aspirin	0.4	0.5	1.9	-1.4	-0.3	-0.4	-0.6	-0.9	-0.2	-1.1	-0.5	0.3	0.3	-0.7	-1.0	-0.9	-0.4	-0.8	-0.7	-0.4
Knee pain experienced in last month	0.4	0.6	2.8	0.7	0.1	0.7	0.3	0.7	0.4	1.7	0.6	-0.4	1.5	1.0	0.8	0.3	-0.0	0.8	-0.2	-0.1
Illnesses of siblings: Diabetes	0.4	0.4	2.1	0.1	0.2	-0.5	-1.0	0.2	-0.5	-1.4	-0.8	-0.2	1.0	1.0	-0.2	-0.5	-0.2	-0.5	-0.6	-0.3
Osteoarthritis (self-reported)	0.4	0.5	3.3	0.2	1.8	0.1	-0.1	-0.0	-0.2	1.3	0.2	-0.6	-0.7	-0.8	0.6	-0.1	-0.9	0.6	-0.5	-0.4
Guilty feelings	0.4	0.6	4.2	-0.4	-1.0	0.1	-0.2	-0.6	0.7	-0.4	-0.3	1.5	2.1	-0.2	-0.7	-0.7	0.3	-0.6	-0.0	0.3
Eye problems/disorders: Glaucoma	0.4	0.5	1.4	-0.3	-0.3	-0.9	-0.7	-0.9	-0.3	-0.9	-0.8	0.3	1.2	0.8	-0.5	-0.9	-0.1	-0.6	-0.6	-0.2
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.7	0.0	-0.2	-1.3	-0.9	-0.6	-0.5	-0.9	-0.9	-0.6	0.5	0.8	-0.2	-0.6	-0.4	-0.1	0.1	-0.5
Alcohol drinker status: Previous	0.4	0.4	1.9	0.8	1.4	-0.3	0.7	0.8	0.5	-0.1	0.2	0.2	0.8	0.4	0.9	0.2	0.1	1.0	0.3	0.4
Alzheimer’s Disease (in father)	0.3	0.3	0.8	-0.1	-0.6	-0.9	-0.4	-0.8	-0.1	-0.5	-0.5	0.5	-0.3	-0.9	-0.3	-0.9	-0.1	-0.3	-0.4	-0.4
Major Depression (MDD)	0.3	0.3	1.7	-0.2	-0.4	-0.2	0.8	0.2	0.8	0.6	0.2	0.5	-0.3	-0.0	0.0	0.1	0.8	0.5	1.3	0.7
HbA1C	0.3	0.3	1.7	-0.6	-0.9	-0.1	0.1	-0.2	-0.2	-0.1	0.6	-0.9	-1.3	-0.4	-0.4	0.6	-0.3	-0.3	0.1	-0.3
Smoking Status	0.3	0.8	1.6	-1.0	-0.2	-0.9	-0.6	-1.2	-0.9	-0.5	-1.1	-0.7	0.5	-0.9	-0.7	-1.3	-1.1	-0.4	-1.0	-0.9
Respiratory disease	0.3	0.6	1.3	0.9	0.9	0.5	0.6	1.1	0.4	0.2	0.6	0.4	-0.1	1.0	0.9	0.5	1.0	0.9	1.2	1.0
Neuroticism	0.3	0.6	3.3	0.4	0.1	0.0	0.9	0.1	1.3	0.4	0.6	1.4	1.8	0.2	0.4	0.1	0.8	0.6	0.7	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.2	-0.3	0.7	-0.1	-0.2	-0.7	0.1	-1.0	-0.6	1.1	0.7	-0.3	-0.2	-1.1	0.4	-0.4	0.2	0.1
Qualifications: CSEs or equivalent	0.3	0.4	2.7	-1.4	-1.6	-0.1	-0.1	-0.1	0.0	0.1	0.0	-0.2	-0.1	-1.1	-0.9	-0.4	-0.2	-0.4	0.1	-0.4
Leg predicted mass (left)	0.3	1.3	6.6	-1.9	-2.6	-0.7	0.3	-1.5	0.1	-0.9	0.6	-0.7	0.7	-0.2	-1.6	0.9	-0.9	-1.4	-1.1	-0.7
Past tobacco smoking	0.3	0.6	2.1	0.5	-0.1	0.5	0.6	0.7	0.4	1.4	1.1	-0.6	-1.3	0.4	0.5	1.4	0.2	0.4	0.6	0.2
Nervous feelings	0.3	0.5	1.4	0.4	-1.2	-0.9	0.4	-0.0	0.9	-0.2	-0.3	1.1	1.0	-0.7	0.2	-0.8	0.7	0.6	0.7	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.7	0.8	0.4	1.3	0.4	1.2	0.7	-0.5	0.7	0.9	-0.3	1.1	0.5	0.8	1.1	-0.0	0.5	0.9
Heart attack	0.3	0.3	1.5	-0.1	0.8	0.0	-0.4	-0.4	-0.6	-1.1	-0.3	-0.5	0.2	-0.3	-0.0	-0.2	-0.9	0.0	-1.2	-0.4
Neuroticism score	0.3	0.7	3.0	-0.1	-1.1	-1.1	0.2	-0.2	1.0	-0.2	-0.3	1.5	1.7	-0.1	-0.2	-0.8	0.9	0.2	0.8	0.5
Hair/balding pattern: Pattern 3	0.3	0.4	1.8	-0.4	-1.0	0.0	-0.1	-0.6	-0.8	-0.1	-0.2	-1.4	-0.7	-0.1	-0.4	0.1	-0.8	-0.1	-0.5	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.7	0.2	1.3	1.0	-0.3	0.4	0.1	-0.3	-0.0	0.4	0.6	-0.8	0.3	-0.1	-0.6	0.1	-0.9	-0.4
Exposure to tobacco smoke at home	0.3	0.3	1.2	-0.6	-0.9	0.3	-0.5	-0.2	0.0	1.0	0.2	0.5	-0.7	0.2	-0.7	0.3	0.5	-1.1	-0.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.1	-1.2	-0.0	0.1	0.1	0.8	0.6	0.3	1.1	0.3	0.6	-0.2	0.3	1.2	-0.5	0.5	0.8
Medication: Paracetamol	0.3	0.5	2.8	0.3	0.6	1.1	0.5	0.7	0.4	1.7	0.2	0.4	0.8	0.1	0.5	-0.2	0.5	0.7	0.7	0.5
Qualifications: College or University degree	0.3	1.0	3.9	-0.4	-1.0	-0.4	0.3	-0.2	0.9	-1.7	-0.4	1.0	1.9	1.3	-0.2	-0.4	0.8	0.4	2.0	0.6
Had major operations	0.3	0.4	1.0	0.3	0.9	-0.1	0.2	0.9	0.8	0.3	0.2	1.0	0.0	0.2	0.4	0.3	0.8	0.4	0.6	1.0
Family relationship satisfaction	0.3	0.4	1.4	-0.6	-1.1	-0.8	-0.7	-0.7	0.0	-1.2	-0.6	0.2	0.3	-0.3	-0.7	-0.6	-0.1	-0.6	-0.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.7	0.2	-0.9	-0.3	0.7	1.6	0.6	1.0	0.1	-0.1	-0.4	-0.5	0.2	0.4	-0.1	0.8	0.2	0.2
Supplements: Vitamin C	0.3	0.4	1.0	-0.4	0.5	0.5	-0.3	0.4	0.4	-0.8	-0.1	0.8	-0.4	0.9	-0.4	0.0	0.9	-0.7	0.5	1.0
Average weekly red wine intake	0.3	0.5	2.2	1.0	0.7	0.1	0.5	0.8	0.2	-0.7	0.2	-0.5	0.8	0.4	1.1	0.2	-0.2	1.5	0.4	-0.2
Ever had bowel cancer screening	0.3	0.3	0.9	-0.2	-0.3	0.3	0.9	0.0	0.5	0.8	0.9	-0.3	-0.9	-0.8	0.1	0.9	0.0	0.2	0.4	0.2
Diabetes diagnosed by doctor	0.3	0.5	1.8	-0.2	0.8	0.9	0.2	0.1	0.9	-0.5	0.2	1.1	1.3	-0.2	0.3	-0.5	0.4	0.6	0.9	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.7	0.0	1.3	-0.4	-0.8	0.8	-0.5	0.3	-0.6	-0.2	-1.1	-0.4	-0.0	-0.5	-0.4	0.0	-0.7	0.0
Mother’s age at death	0.3	0.4	2.3	0.4	1.5	-0.1	-0.5	0.1	-0.4	-0.7	-0.6	-0.3	-1.2	-0.5	0.4	-0.3	-0.2	0.4	0.0	-0.1
Medication: Blood pressure	0.3	0.6	2.5	-1.2	-0.4	1.6	0.3	-0.2	-0.1	0.8	0.8	-0.8	-0.1	-0.6	-0.7	0.6	-1.0	-0.7	-0.7	-0.6
Age started oral contraceptive pill	0.3	0.3	2.5	-0.6	-0.4	1.6	0.6	-0.0	0.1	0.3	0.3	0.1	-0.8	-0.8	-0.4	0.4	-0.0	-0.4	0.0	0.2
Diastolic blood pressure, automated reading	0.3	0.9	5.4	0.1	-0.1	-0.9	-0.1	0.3	-1.0	1.5	0.2	-1.3	-2.3	-1.2	-0.1	0.5	-0.5	-0.4	-1.5	-0.5
Unable to work because of sickness or disability	0.3	0.4	1.0	0.6	0.1	-0.1	0.5	1.0	0.7	1.0	0.2	0.3	0.3	0.4	0.6	0.3	0.7	0.8	0.7	0.8
Myopia	0.3	0.4	0.9	0.2	0.5	0.8	0.7	0.5	0.5	0.8	0.7	-0.0	0.5	0.7	0.4	0.7	0.4	0.6	1.0	0.5
Supplements: Calcium	0.3	0.3	1.3	0.6	0.4	-0.5	0.1	1.1	-0.0	0.2	-0.1	-0.8	-0.6	-0.1	0.7	0.2	-0.1	1.1	0.6	0.2
Depression (Nagel 2018)	0.2	0.3	1.8	-0.4	-0.3	-0.6	-0.2	-0.1	0.0	-0.1	0.1	-0.5	-1.4	-1.1	-0.3	-0.0	-0.3	-0.2	-0.4	-0.3
Worry (Nagel 2018)	0.2	0.4	2.3	0.2	-0.1	-0.5	0.4	-0.3	0.8	-0.7	-0.2	1.5	0.9	-0.1	0.1	-0.8	0.9	0.2	0.9	0.6
Alzheimer’s Disease (in mother)	0.2	0.2	1.4	-0.0	-1.2	1.2	0.3	0.2	-0.3	-0.5	0.1	-0.7	-0.1	-0.1	-0.0	0.2	-0.1	0.1	0.3	-0.4
Mean Putamen Volume	0.2	0.2	0.7	-0.8	-0.1	-0.4	-0.3	-0.8	-0.5	0.1	-0.1	-0.8	0.3	-0.0	-0.5	-0.0	-0.8	-0.3	-0.4	-0.6
Height	0.2	4.2	35.2	-0.7	-2.3	-5.9	0.7	-1.6	1.3	-3.4	-0.2	0.3	2.6	1.1	-0.0	-0.5	0.3	1.5	1.8	0.1
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.3	-0.6	1.1	0.7	0.0	-0.8	0.3	-0.9	-0.1	0.5	0.9	-0.1	0.0	-0.7	0.0	0.5	0.6	0.2
Sensitivity / hurt feelings	0.2	0.3	0.9	0.6	1.0	-0.5	-0.5	-0.8	-0.5	-0.3	-0.6	-0.0	0.6	-0.4	0.2	-0.6	-0.3	-0.1	-0.8	-0.4
Hearing difficulty/problems: Yes	0.2	0.3	1.1	1.1	0.6	-0.6	-0.0	0.9	-0.3	-0.1	0.0	-0.4	-0.9	-0.4	0.9	-0.0	0.2	0.9	0.2	-0.1
Leg fat-free mass (left)	0.2	1.3	6.1	-1.9	-2.5	-0.6	0.4	-1.4	0.2	-0.9	0.7	-0.7	0.7	-0.1	-1.6	1.0	-0.9	-1.4	-1.1	-0.6
Serious illness, injury or assault to yourself	0.2	0.2	2.1	-0.3	0.5	-0.9	-0.2	-0.1	0.3	0.5	0.0	0.3	-0.1	-1.5	-0.1	-0.2	-0.2	0.1	-0.5	-0.0
Supplements: Glucosamine	0.2	0.3	2.2	0.6	0.8	0.4	0.3	0.3	0.4	1.5	0.4	0.3	-0.4	0.1	0.6	0.5	0.2	0.4	0.0	0.5
Sitting height	0.2	1.6	8.6	-1.5	-2.0	-2.9	0.6	-1.7	-0.2	-1.5	0.2	-1.8	-0.5	-0.8	-0.8	0.6	-1.1	0.1	-0.1	-0.8
Hearing difficulty/problems with background noise	0.2	0.4	2.2	0.9	1.5	0.2	-0.4	0.3	-0.0	0.3	-0.1	0.3	1.0	0.7	0.9	-0.4	0.2	0.9	0.1	0.1
Forced vital capacity (FVC)	0.2	0.9	5.1	0.2	-0.6	-2.3	0.9	-0.6	-0.1	-0.5	0.6	-1.8	-0.3	0.1	0.6	1.0	-0.7	1.2	0.6	-0.7
Financial difficulties in last 2 years	0.2	0.3	2.4	-0.7	0.1	-1.6	-0.2	-0.5	-0.1	0.3	-0.3	-0.0	0.2	-0.8	-0.3	-0.7	-0.5	0.1	-0.3	-0.6
Illnesses of siblings	0.2	0.2	1.6	-0.1	-1.3	-0.1	0.1	-0.1	0.7	0.0	-0.1	0.5	-0.6	-0.7	-0.2	-0.1	0.5	0.1	0.7	0.1
Trunk fat-free mass	0.2	0.9	5.6	-1.1	-2.4	-1.2	0.5	-0.9	-0.0	-0.8	0.5	-1.1	-0.5	-0.4	-0.9	1.0	-0.5	-0.8	-0.8	-0.5
Noisy workplace	0.2	0.3	2.6	-0.5	-0.4	-0.0	-0.3	0.3	-0.2	-0.4	-0.2	-0.1	1.6	0.0	-0.5	-0.3	-0.4	-0.5	-0.8	-0.5
Prospective memory result	0.2	0.3	0.7	-0.6	-0.7	0.3	0.8	0.8	0.2	0.8	0.9	-0.3	-0.8	-0.3	-0.1	0.6	0.1	-0.2	-0.3	0.0
Trunk predicted mass	0.2	1.0	6.1	-1.1	-2.5	-1.4	0.3	-1.0	-0.1	-0.9	0.4	-1.1	-0.6	-0.5	-1.0	0.9	-0.6	-0.9	-0.9	-0.5
Standing height	0.2	2.3	20.4	-0.7	-2.3	-4.5	0.6	-1.7	0.5	-2.1	-0.1	-0.8	1.5	0.5	-0.2	-0.0	-0.3	0.9	1.0	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.4	-0.9	-0.3	-0.7	0.2	-0.1	0.3	1.2	0.2	-0.2	0.2	-0.3	-0.5	0.4	-0.3	-0.5	-0.5	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.1	-0.2	0.8	0.8	0.3	-0.1	0.4	1.0	0.7	0.1	0.4	-0.0	0.2	0.2	0.1	0.2	0.5	0.2
Forced vital capacity (FVC), Best measure	0.2	0.9	3.0	0.5	-0.1	-1.7	1.5	-0.2	0.5	-0.0	1.2	-1.1	-0.3	0.2	1.1	1.4	-0.2	1.6	1.0	-0.0
Arm fat-free mass (right)	0.2	1.2	5.8	-0.6	-1.8	0.6	1.9	0.2	1.0	0.8	2.1	-0.9	-0.6	-0.1	-0.1	2.4	-0.0	-0.0	-0.3	0.2
Worry too long after embarrassment	0.2	0.4	0.8	0.7	0.4	-0.1	0.7	-0.1	0.9	0.0	0.2	0.9	0.8	0.2	0.7	-0.0	0.9	0.7	0.5	0.6
Medication for pain relief, constipation, heartburn	0.2	0.4	1.6	0.8	-0.0	-0.2	0.4	0.3	-0.4	-0.2	0.6	-1.3	-1.0	0.1	0.4	1.3	-0.8	-0.0	-0.6	-0.5
Arm predicted mass (right)	0.2	1.1	5.2	-0.5	-1.6	0.3	1.7	0.1	0.8	0.6	2.0	-1.0	-0.7	-0.1	-0.1	2.3	-0.1	0.0	-0.4	0.1
Comparative height size at age 10	0.2	1.1	7.5	-0.6	-1.3	-2.7	0.9	-0.5	1.0	-1.0	0.3	0.1	1.4	0.6	-0.0	0.2	0.1	0.9	1.4	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.6	0.1	-0.7	-1.3	-0.2	0.4	-0.1	-0.7	-0.4	-0.3	-0.5	0.3	-0.2	-0.2	0.2	-0.0	0.6	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.4	-0.1	0.2	1.2	0.3	0.3	0.2	0.3	0.6	0.1	-0.7	-0.1	0.0	0.6	0.2	-0.2	-0.3	0.4
Whole body fat-free mass	0.2	1.0	5.9	-1.3	-2.4	-0.9	0.6	-1.0	0.1	-0.8	0.8	-1.0	-0.1	-0.3	-1.1	1.2	-0.6	-0.9	-0.9	-0.5
Leg fat-free mass (right)	0.2	1.2	5.3	-1.8	-2.3	-0.5	0.4	-1.5	0.3	-1.0	0.7	-0.5	1.1	0.1	-1.5	0.9	-0.8	-1.3	-1.0	-0.6
Mood swings	0.2	0.3	1.5	0.0	-1.2	-0.8	-0.5	0.1	-0.1	-0.3	-0.5	0.2	-0.2	-0.9	-0.3	-0.7	0.1	-0.3	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.5	0.1	0.2	-0.6	-0.5	-0.7	-0.9	-1.2	-0.2	-1.2	-1.2	-0.6	0.0	0.1	-0.8	-0.0	-0.0	-0.7
Whole body water mass	0.2	1.1	6.4	-1.4	-2.5	-0.9	0.6	-1.1	0.1	-0.8	0.8	-1.0	-0.1	-0.4	-1.2	1.1	-0.7	-1.0	-1.0	-0.6
Leg predicted mass (right)	0.2	1.2	5.5	-1.8	-2.3	-0.5	0.4	-1.4	0.3	-1.0	0.7	-0.5	1.0	0.1	-1.5	0.9	-0.8	-1.3	-1.0	-0.6
Medication: Paracetamol	0.2	0.2	0.7	-0.4	0.4	0.8	-0.2	-0.1	-0.1	0.7	-0.5	0.1	0.7	-0.7	-0.1	-0.9	-0.4	0.2	-0.4	-0.3
Basal metabolic rate	0.2	0.9	4.5	-1.3	-2.1	-0.3	1.0	-0.6	0.6	-0.3	1.3	-0.8	0.3	-0.0	-0.9	1.6	-0.5	-0.7	-0.8	-0.2
Arm fat-free mass (left)	0.2	0.9	4.0	-0.9	-2.0	-0.3	1.1	-0.4	0.3	0.1	1.4	-1.2	-0.9	-0.6	-0.6	1.8	-0.5	-0.5	-0.8	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.3	0.1	1.1	0.2	-0.3	-0.2	-0.4	-1.1	-0.3	-0.3	0.3	-0.3	0.2	-0.2	-0.7	0.2	-1.1	-0.2
Impedance of whole body	0.2	1.0	3.1	0.8	1.1	-1.5	0.1	0.1	0.5	-0.1	-0.4	0.6	1.6	0.8	1.1	-1.0	0.5	1.8	1.7	0.3
Arm predicted mass (left)	0.2	1.1	4.4	-0.9	-2.1	-0.2	1.3	-0.3	0.3	0.3	1.5	-1.4	-1.0	-0.7	-0.6	2.0	-0.6	-0.4	-0.8	-0.3
Depressed Affect (Nagel 2018)	0.1	0.2	1.7	-0.1	-0.7	-1.3	-0.2	-0.5	-0.0	-0.7	-0.5	-0.0	0.5	-0.2	-0.2	-0.6	-0.2	-0.0	-0.3	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.9	0.5	0.1	-0.4	0.1	-0.3	0.6	-0.6	-0.4	1.0	0.9	-0.0	0.2	-0.5	0.4	0.2	0.1	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.5	0.4	0.7	0.2	0.1	-0.3	-0.0	-0.7	-0.0	0.4	0.6	0.3	0.3	-0.2	0.2	0.3	0.0	0.3
Age at First Birth	0.1	0.1	1.0	0.1	-0.2	0.1	0.4	0.5	0.2	-0.2	0.4	-0.2	-0.0	0.3	0.1	1.0	0.0	-0.2	-0.2	0.2
Blood White Count	0.1	1.0	3.0	-0.8	0.5	1.7	-0.8	-0.4	-1.3	-0.0	0.1	-1.1	-1.6	-0.4	-0.8	0.2	-1.0	-1.4	-1.6	-0.5
Heel T-Score	0.1	1.0	5.4	0.4	0.9	1.3	1.0	2.3	-0.1	-0.0	1.4	-0.7	-1.4	0.2	0.6	1.4	0.1	0.2	-0.0	0.2
Hair Pigment	0.1	2.5	5.6	-1.3	0.1	-2.2	-1.4	-1.0	-2.2	0.0	-1.4	-2.2	-1.2	-1.7	-1.2	-1.1	-2.4	-1.1	-2.2	-1.8
Tanning	0.1	1.3	4.2	0.2	-0.5	-1.9	-1.5	-0.7	-0.3	-1.9	-1.9	1.1	-0.0	-1.0	-0.5	-2.0	0.1	-0.5	0.1	-0.4
Hand grip strength (left)	0.1	0.3	2.8	0.5	-0.7	0.1	0.2	0.2	-0.0	0.0	0.1	-0.3	-1.7	-0.4	0.3	0.5	0.3	0.1	0.7	0.0
Hand grip strength (right)	0.1	0.3	1.7	0.9	-0.6	-0.3	0.4	0.8	0.2	0.5	0.3	-0.2	-1.3	0.1	0.5	0.7	0.6	0.4	0.7	0.2
Maternal smoking around birth	0.1	0.2	0.9	-0.4	-0.5	0.7	0.3	0.1	0.5	0.9	1.0	0.3	-0.0	0.1	-0.2	0.5	0.3	-0.3	0.1	0.4
Pain all over the body in last month	0.1	0.1	0.8	0.3	0.1	-0.0	-0.1	0.9	-0.2	0.2	-0.2	-0.3	-0.2	-0.2	0.3	-0.3	0.2	0.4	0.0	0.1
Hip circumference	0.1	0.6	1.7	-1.1	-1.0	0.4	0.5	-0.4	0.6	-0.3	1.1	-0.0	1.1	0.0	-0.8	1.1	-0.4	-0.9	-1.3	-0.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	2.3	0.1	-0.2	-1.5	0.2	-1.0	0.1	-1.2	0.2	-0.5	1.1	0.7	0.2	0.3	-0.2	0.5	0.6	-0.3
Asthma	0.1	0.1	0.3	-0.5	-0.4	-0.1	-0.5	-0.6	-0.6	-0.4	-0.1	-0.2	0.3	0.6	-0.5	-0.3	0.1	-0.5	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	1.1	0.3	-0.0	-0.7	1.0	-0.5	0.6	-0.5	1.1	-0.2	0.9	0.8	0.6	1.0	0.1	0.9	0.9	0.2
Hair/balding pattern: Pattern 4	0.1	0.4	2.5	-0.5	0.9	-1.6	-0.5	-0.8	0.3	0.1	-0.6	0.3	0.0	0.0	0.0	-0.9	-0.1	0.2	0.6	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.8	-0.2	-0.0	-0.5	0.1	-0.4	0.5	0.3	0.1	0.5	0.6	-0.2	-0.0	-0.0	0.2	0.1	0.9	0.2
Eye problems/disorders: None of the above	0.1	0.1	0.6	-0.5	-0.5	0.1	0.1	0.5	0.3	0.1	0.0	0.4	0.1	-0.4	-0.4	-0.0	0.0	-0.1	0.8	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.6	0.2	-0.1	-0.2	-0.5	-0.2	-0.3	-0.2	0.1	-0.1	-0.2	-0.3	-0.5	0.2	-0.4	-0.3	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	0.7	0.0	-0.2	-0.2	0.3	0.3	0.2	-0.2	0.2	-0.4	0.1	0.3	0.1	0.3	0.2	-0.2	0.2
Medication: Atorvastatin	0.1	0.1	0.4	0.0	-0.6	-0.6	0.3	0.3	0.2	-0.3	0.0	-0.0	-0.1	-0.0	0.2	-0.0	0.3	0.7	0.3	0.2
Heart disease (siblings)	0.1	0.2	0.9	0.4	1.0	-0.5	-0.1	0.7	-0.3	-0.1	-0.0	-0.1	-0.4	0.1	0.3	0.1	-0.2	-0.1	-0.8	-0.1
Asthma (self-reported)	0.0	0.1	0.3	-0.4	-0.3	0.1	-0.4	-0.5	-0.3	-0.2	0.1	-0.0	0.3	0.5	-0.3	-0.1	0.2	-0.4	-0.1	0.1

Hub : Genes

C7orf49

Models

Trait associations