Hub : Genes

C8orf12

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Brain Lower Grade Glioma 0.0723 0.0271 7.2e-08 0.102 0.045 0.088 NA 0.005 1.2e-11 7.0e-06 3.4e-10 NA 0.07900
2 TCGA Pheochromocytoma and Paraganglioma 0.2640 0.0970 6.0e-05 0.038 0.103 0.094 NA 0.097 1.3e-02 6.8e-05 1.5e-04 NA 0.00012

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.0 3.1 4.1 -1.5 2.0
Bipolar Disorder or Schizophrenia 3.1 7.5 9.2 -3.0 2.4
Depressed Affect (Nagel 2018) 0.0 0.1 0.1 0.3 -0.2
Depression (Nagel 2018) 0.3 0.4 0.6 -0.5 0.8
Intelligence (Savage-Jansen 2018) 0.8 2.5 2.7 1.7 -1.5
Neuroticism (Nagel 2018) 0.2 0.4 0.6 0.8 0.4
Schizophrenia (2018) 2.3 4.9 7.4 -2.7 1.5
Schizophrenia vs Biploar Disorder 0.3 0.5 0.9 -0.9 0.2
Worry (Nagel 2018) 1.3 2.7 3.9 -1.2 2.0
Alzheimer’s Disease (in mother) 0.5 0.6 1.2 -0.2 1.1
Alzheimer’s Disease (in father) 0.1 0.1 0.1 -0.4 -0.0
Alzheimer’s Disease (including proxy) 0.0 0.0 0.1 -0.1 0.3
Crohns Disease (2017) 1.6 3.4 4.2 -1.6 2.0
Irritable Bowel Disease (IBD) 0.2 0.5 0.6 -0.8 0.7
Ulcerative Colitis (UC) 0.1 0.1 0.2 -0.3 -0.4
Major Depression (MDD) 0.2 0.2 0.2 0.5 -0.4
Reaction Time 0.4 0.7 1.2 0.5 -1.1
Verbal and Numeric Reasoning (VNR) 1.4 3.5 4.9 2.2 -1.4
Breast Cancer 1.1 2.7 4.0 -2.0 1.1
Ovarian Cancer 0.4 0.5 0.8 0.5 0.9
Prostate Cancer 2.0 2.8 5.3 -2.3 0.6
Age at First Birth 0.6 0.9 1.3 1.1 -0.7
Bipolar Disorder (2011) 1.1 1.1 1.8 -1.3 0.6
Body Mass Index (BMI) (2010) 0.7 1.0 1.2 -1.1 0.9
Coronary Artery Disease (CAD) 1.3 1.5 1.7 1.3 -1.2
Crohns Disease (2012) 0.7 1.1 1.2 -1.1 0.9
Mean Putamen Volume 0.0 0.0 0.1 -0.1 -0.3
Fasting Glucose 1.1 1.3 1.6 -1.1 1.3
HbA1C 0.4 0.4 0.5 -0.6 0.7
HDL Cholesterol 0.3 0.4 0.8 0.3 -0.9
LDL Cholesterol 0.3 0.5 0.6 -0.6 0.8
Lupus 8.0 12.1 20.3 -4.5 2.0
Neuroticism (2016) 18.4 26.6 35.4 6.0 -4.2
Primary Biliary Cirrhosis 1.0 1.5 2.5 -1.6 0.7
Rheumatoid Arthritis 0.5 0.7 1.1 0.5 1.0
Schizophrenia (2014) 2.9 6.5 10.4 -3.2 1.6
Triglycerides 3.8 6.3 7.8 2.2 -2.8
Type 2 Diabetes (T2D) (2012) 0.5 0.6 0.8 -0.9 0.6
Ulcerative Colitis 0.4 0.6 1.2 0.2 -1.1
Blood Eosinophil Count 0.0 0.1 0.1 -0.1 0.4
Blood Platelet Count 0.0 0.3 0.6 -0.1 0.8
Blood Red Count 0.1 1.3 2.6 -0.2 -1.6
Blood White Count 0.6 4.4 6.8 -2.6 1.4
Heel T-Score 0.2 1.4 2.2 -1.5 -0.7
BMI 0.5 2.9 3.3 1.8 -1.6
Height 0.0 0.4 0.6 0.4 -0.8
Waist Hip Ratio (WHR) 0.0 0.1 0.1 0.3 -0.3
Systolic Blood Pressure 0.3 1.5 2.9 1.7 0.1
Smoking Status 0.2 0.6 1.2 -0.1 -1.1
Allergy or Eczema 0.3 0.8 1.5 0.1 -1.2
Cardiovascular Disease 0.1 0.3 0.5 0.7 -0.4
Hypothyroidism (self reported) 0.4 1.0 1.3 0.8 -1.1
Respiratory disease 0.1 0.1 0.1 -0.4 0.3
Type 2 Diabetes (T2D) (2018) 0.9 1.7 2.8 -1.7 -0.7
Lung FEV1/FVC ratio 0.2 1.1 1.8 -0.6 1.3
Lung FVC 0.2 1.0 2.0 -1.4 -0.2
Neuroticism 0.3 0.8 0.8 -0.9 0.9
Chronotype (morning person) 0.6 1.4 2.7 0.1 -1.6
Hair Pigment 0.0 0.6 1.0 -0.4 1.0
Tanning 0.0 0.4 0.9 0.2 0.9
Hand grip strength (left) 1.1 2.8 5.3 -2.3 0.6
Number of treatments/medications taken 0.8 1.4 2.7 0.1 1.6
Average weekly spirits intake 0.7 0.8 1.6 0.2 -1.3
Sensitivity / hurt feelings 9.9 16.9 24.2 4.9 -3.1
Frequency of depressed mood in last 2 weeks 1.7 2.4 3.8 1.0 -1.9
Hearing difficulty/problems: Yes 0.2 0.2 0.5 0.1 -0.7
Relative age of first facial hair 0.1 0.2 0.2 -0.5 0.5
Other serious medical condition/disability diagnosed by doctor 0.9 1.1 2.1 1.4 -0.4
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.0 -0.5 1.4
Ever had hysterectomy (womb removed) 4.9 5.6 6.9 -2.6 2.1
Systolic blood pressure, automated reading 4.5 13.0 15.5 -3.2 3.9
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.4 0.2 -0.6
Angina 0.6 0.7 1.1 -1.0 -0.6
Medication for hormone replacement therapy 0.3 0.3 0.6 -0.1 0.8
Vitamin and mineral supplements 0.7 0.9 0.9 1.0 -0.9
Supplements: Zinc 1.1 1.2 2.4 -0.1 1.5
Medication: Co-codamol 1.0 1.2 2.1 -0.6 1.4
Medication: Metformin 1.5 2.1 4.1 -2.0 0.4
Diabetes (father) 1.2 1.4 1.7 -1.3 1.1
Diabetes (mother) 0.4 0.5 0.6 -0.7 0.7
Severe depression (siblings) 0.2 0.2 0.4 -0.6 0.3
Pack years adult smoking proportion 2.2 3.4 4.6 -2.1 1.5
Impedance of leg (right) 3.1 15.0 21.1 4.6 -3.0
Leg fat-free mass (left) 1.2 6.6 7.8 -2.8 2.3
Trunk fat percentage 1.2 4.9 8.4 -1.2 2.9
Hand grip strength (right) 0.9 2.3 4.6 -2.1 -0.1
Townsend deprivation index at recruitment 2.8 3.9 4.2 2.1 -1.9
Current tobacco smoking 6.9 11.2 16.2 -4.0 2.5
Average weekly fortified wine intake 3.1 3.6 6.6 2.6 -0.8
Maternal smoking around birth 0.1 0.1 0.1 -0.3 -0.4
Fed-up feelings 4.6 8.4 9.8 2.6 -3.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.5 0.4 -0.7
Relative age voice broke 0.1 0.1 0.1 -0.3 -0.3
Taking other prescription medications 0.1 0.2 0.3 0.5 0.3
Age when periods started (menarche) 1.5 3.7 4.0 2.0 -1.9
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 1.2 -0.7 1.1
Heel bone mineral density (BMD) T-score, automated (left) 20.2 45.8 46.3 -6.7 6.8
Tinnitus: Yes, but not now, but have in the past 2.1 2.3 3.4 -1.8 1.1
Qualifications: CSEs or equivalent 0.3 0.3 0.4 0.6 0.5
Serious illness, injury or assault to yourself 0.2 0.3 0.4 0.4 -0.6
High blood pressure 4.7 13.2 18.4 -2.8 4.3
Hayfever, allergic rhinitis or eczema 0.4 0.8 1.6 -1.2 0.3
Multivitamins +/- minerals 0.7 0.8 1.5 -1.2 0.4
Stomach or abdominal pain in last month 2.5 3.1 5.4 2.3 -0.9
Supplements: Glucosamine 0.3 0.4 0.6 -0.8 0.4
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.3 0.4 0.5
Medication: Atenolol 1.3 1.6 2.1 -1.1 1.4
Medication: Levothyroxine sodium 6.0 10.2 10.6 3.3 -3.1
Sitting height 0.7 4.8 6.5 -2.5 1.8
Chronic bronchitis/emphysema (father) 0.4 0.5 0.6 -0.6 0.8
High blood pressure (mother) 0.1 0.1 0.2 0.1 0.4
Body mass index (BMI) 4.1 17.4 17.9 -4.1 4.2
Impedance of leg (left) 3.2 15.7 21.2 4.6 -3.2
Leg predicted mass (left) 1.3 6.8 7.8 -2.8 2.4
Trunk fat mass 1.3 5.7 8.3 -1.8 2.9
Waist circumference 0.2 0.8 1.1 -0.6 1.1
Number of incorrect matches in round 0.6 1.0 1.8 1.3 -0.5
Past tobacco smoking 0.1 0.2 0.4 -0.1 -0.6
Alcohol usually taken with meals 0.7 1.1 2.1 -1.4 0.4
Nervous feelings 14.3 26.7 30.2 5.5 -4.8
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.2 0.3 -0.4
Hearing difficulty/problems with background noise 2.0 3.2 4.2 1.5 -2.0
Hair/balding pattern: Pattern 2 1.5 1.9 3.8 -0.0 1.9
Had menopause 1.7 2.2 2.4 -1.6 1.4
Had other major operations 0.9 1.1 1.2 -1.1 1.0
Forced vital capacity (FVC) 1.1 4.4 7.1 1.3 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 21.8 50.0 52.7 -7.3 6.9
Ever unenthusiastic/disinterested for a whole week 1.5 1.8 3.6 1.9 0.1
Qualifications: None of the above 0.0 0.1 0.1 0.3 0.3
Financial difficulties in last 2 years 0.1 0.2 0.2 -0.5 0.3
Mouth/teeth dental problems 1.1 1.7 2.8 0.8 -1.7
Heart attack 0.1 0.1 0.2 0.5 -0.1
Allergy 1.2 2.8 4.0 2.0 -1.3
Pain all over the body in last month 1.3 1.4 2.3 -1.5 0.8
Diabetes (self-reported) 0.8 1.3 2.5 -1.6 0.3
Hayfever/allergic rhinitis (self-reported) 1.6 2.1 3.4 0.9 -1.9
Medication: Ramipril 1.5 1.9 2.3 -1.2 1.5
Medication: Simvastatin 0.0 0.1 0.1 -0.3 0.1
Fluid intelligence score 2.3 4.8 5.5 2.3 -2.0
Illnesses of siblings 1.4 2.0 2.7 1.1 -1.6
Neuroticism score 12.6 26.2 29.7 5.5 -4.8
Weight 1.4 6.6 6.8 -2.5 2.6
Impedance of arm (right) 3.4 16.0 24.2 4.9 -2.8
Arm fat percentage (right) 2.4 9.6 13.7 -2.4 3.7
Trunk fat-free mass 0.5 3.0 4.8 -2.2 1.1
Hip circumference 1.9 8.0 8.2 -2.9 2.8
Time employed in main current job 1.7 2.0 3.7 1.9 -0.5
Alcohol intake versus 10 years previously 0.7 1.0 1.9 -0.4 -1.4
Father’s age at death 3.9 5.3 6.9 1.9 -2.6
Worrier / anxious feelings 11.2 21.2 29.5 5.4 -3.6
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 1.5 1.2 -0.7
Falls in the last year 0.0 0.0 0.1 -0.0 0.2
Hair/balding pattern: Pattern 3 1.4 2.1 3.8 0.7 -1.9
Number of live births 0.3 0.4 0.9 0.9 0.0
Forced expiratory volume in 1-second (FEV1) 1.9 6.5 9.4 1.9 -3.1
Pulse rate 1.2 2.0 4.0 2.0 0.1
Happiness 0.1 0.2 0.3 0.5 -0.2
Noisy workplace 0.3 0.4 0.4 0.6 -0.7
Qualifications: A levels/AS levels or equivalent 1.6 3.5 4.3 2.1 -1.7
Serious illness, injury or assault of a close relative in last 2 years 3.7 4.2 5.8 2.4 -1.6
Mouth/teeth dental problems: Dentures 2.6 4.4 7.3 -1.3 2.7
Asthma 2.4 4.6 5.8 -2.4 1.9
Medication: Ibuprofen (e.g. Nurofen) 3.8 4.9 7.1 2.7 -1.6
Medication: Cholesterol lowering 0.5 0.8 1.4 1.2 -0.4
Depression (self-reported) 1.5 1.8 2.3 1.1 -1.5
Medication: Lansoprazole 0.8 0.9 1.3 -0.7 1.2
Prospective memory result 0.8 0.9 1.8 0.2 -1.3
Lung cancer (father) 0.1 0.1 0.2 -0.2 0.4
Illnesses of mother 1.0 1.3 2.5 -1.6 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.2 8.6 1.9 -2.9
Pulse wave Arterial Stiffness index 1.0 1.2 1.8 -0.8 1.3
Impedance of arm (left) 3.0 13.8 20.9 4.6 -2.6
Arm fat mass (right) 2.4 9.7 11.1 -2.9 3.3
Trunk predicted mass 0.5 2.9 4.8 -2.2 1.0
Standing height 0.8 8.4 8.5 2.9 -2.9
Length of working week for main job 0.9 1.0 1.4 -0.7 1.2
Exposure to tobacco smoke at home 0.4 0.5 0.9 -0.1 0.9
Breastfed as a baby 3.6 4.5 6.4 1.6 -2.5
Tense / ‘highly strung’ 4.4 7.3 8.6 2.5 -2.9
Seen doctor (GP) for nerves, anxiety, tension or depression 2.7 4.1 4.4 2.1 -2.0
Hair/balding pattern: Pattern 4 0.9 2.1 2.9 1.7 -1.1
Birth weight of first child 0.8 1.5 2.9 -0.4 1.7
Peak expiratory flow (PEF) 3.5 8.1 12.8 1.9 -3.6
Pulse wave reflection index 1.0 1.2 2.2 -1.5 0.4
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.6 0.8 0.4
Loud music exposure frequency 0.1 0.1 0.2 0.4 0.1
Qualifications: O levels/GCSEs or equivalent 1.8 2.8 4.2 2.0 -1.2
Mouth/teeth dental problems: Bleeding gums 3.1 4.0 4.5 -1.9 2.1
Blood clot in the leg (DVT) 1.5 1.9 2.2 -1.3 1.5
Medication: Paracetamol 1.5 2.5 3.7 1.9 -1.1
Headache pain in last month 2.3 3.9 5.1 2.3 -1.6
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 1.4 0.6 -1.2
Glaucoma (self-reported) 0.4 0.4 0.8 -0.2 0.9
Gout (self-reported) 0.2 0.3 0.5 0.7 0.3
Hypothyroidism/myxoedema (self-reported) 8.6 16.7 17.3 4.2 -4.0
Medication: Amlodipine 1.2 1.6 1.9 -1.2 1.4
Medication: Ventolin 100micrograms inhaler 0.4 0.5 0.8 -0.9 0.4
Birth weight 0.1 0.1 0.2 -0.5 0.3
Chronic bronchitis/emphysema (mother) 1.6 1.9 2.5 1.6 -1.1
High blood pressure (siblings) 1.5 2.1 4.2 -0.2 2.1
Forced vital capacity (FVC), Best measure 0.7 2.4 4.6 0.5 -2.1
Body fat percentage 1.5 6.0 9.5 -1.6 3.1
Leg fat percentage (right) 2.0 7.4 10.6 -2.0 3.2
Arm fat-free mass (right) 1.1 5.7 9.4 -3.1 1.4
Exposure to tobacco smoke outside home 0.7 0.9 1.3 1.1 -0.7
Comparative body size at age 10 5.0 13.7 21.5 -4.6 2.4
Number of full brothers 0.2 0.2 0.4 -0.7 -0.0
Worry too long after embarrassment 11.0 18.5 21.9 4.7 -3.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.4 0.7 -0.2
Wheeze or whistling in the chest in last year 1.6 2.8 3.7 -1.4 1.9
Number of children fathered 1.9 2.2 3.4 -1.8 1.0
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 1.0 0.7 -1.0
Age at first live birth 1.7 3.0 4.5 1.2 -2.1
Pulse wave peak to peak time 1.4 1.7 2.2 1.1 -1.5
Health satisfaction 3.4 4.5 6.9 -1.4 2.6
Shortness of breath walking on level ground 0.5 0.6 1.0 1.0 -0.4
Qualifications: College or University degree 0.5 1.6 3.0 -0.4 -1.7
Eye problems/disorders: None of the above 1.1 1.2 2.1 1.5 -0.5
Mouth/teeth dental problems: Loose teeth 3.0 3.6 5.3 -1.4 2.3
Emphysema/chronic bronchitis 2.7 3.0 4.8 -2.2 1.1
Medication for pain relief, constipation, heartburn 1.5 2.6 4.5 -2.1 0.8
Neck or shoulder pain in last month 1.1 1.5 1.8 1.1 -1.3
Medication: Blood pressure 2.4 4.1 4.6 -2.2 1.9
Angina (self-reported) 0.7 0.9 1.4 -1.2 -0.6
Migraine (self-reported) 0.0 0.0 0.1 0.0 -0.3
Medication: Ibuprofen 3.4 4.1 6.0 2.5 -1.5
Medication: Allopurinol 0.1 0.1 0.2 -0.4 0.2
Medication: Omeprazole 0.5 0.6 1.0 0.5 1.0
Medication: Seretide 50 evohaler 0.1 0.1 0.1 -0.3 -0.3
Mean time to correctly identify matches 0.0 0.1 0.1 0.2 -0.3
Heart disease (mother) 1.9 2.3 4.2 2.1 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 5.8 6.9 7.7 2.5 -2.8
Whole body fat mass 1.6 6.7 8.5 -2.2 2.9
Leg fat mass (right) 2.5 9.6 11.8 -2.7 3.4
Arm predicted mass (right) 1.2 5.9 9.6 -3.1 1.5
Pulse rate, automated reading 0.5 1.6 2.9 -0.5 1.7
Alcohol intake frequency. 0.0 0.1 0.1 0.4 -0.0
Comparative height size at age 10 0.1 0.4 0.9 -0.2 0.9
Number of full sisters 2.2 2.7 3.4 -1.8 1.4
Suffer from ‘nerves’ 4.0 6.2 6.4 2.5 -2.5
Overall health rating 2.6 5.6 7.4 -2.7 2.0
Chest pain or discomfort 1.7 2.5 3.8 1.1 -1.9
Had major operations 0.5 0.5 0.8 -0.9 0.6
Age at last live birth 5.9 8.6 11.3 2.4 -3.4
Family relationship satisfaction 1.6 2.0 2.7 1.6 -1.2
Leg pain on walking 0.6 0.7 1.2 -1.1 -0.5
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.1 0.3 -0.4
Commuting to job workplace: Car/motor vehicle 0.6 0.7 0.9 -0.7 1.0
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.3 -0.6 0.3
Medication: Aspirin 0.5 0.6 1.2 -1.1 0.2
Supplements: Vitamin C 0.3 0.4 0.5 -0.5 0.7
Knee pain experienced in last month 0.2 0.3 0.5 -0.7 0.4
Hypertension (Self-reported) 5.4 15.0 20.0 -3.2 4.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 0.6 -0.8 0.6
Illnesses of father: Heart disease 0.1 0.2 0.3 -0.1 -0.6
Illnesses of siblings: Diabetes 3.3 4.1 8.2 -2.9 0.1
Smoking status: Previous 1.0 1.6 1.8 1.3 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 0.6 0.0 0.8
Whole body fat-free mass 0.8 4.7 6.8 -2.6 1.6
Leg fat-free mass (right) 1.2 6.4 8.0 -2.8 2.2
Arm fat percentage (left) 2.6 10.2 13.9 -2.5 3.7
Average weekly red wine intake 0.3 0.4 0.6 -0.8 -0.4
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.5 -0.0 -0.7
Mood swings 4.5 8.1 8.2 2.9 -2.8
Loneliness, isolation 1.1 1.5 1.7 1.3 -1.1
Long-standing illness, disability or infirmity 0.5 0.8 1.0 1.0 0.8
Ever had bowel cancer screening 0.3 0.3 0.6 0.8 -0.1
Diabetes diagnosed by doctor 0.8 1.4 2.6 -1.6 0.3
Ever had stillbirth, spontaneous miscarriage or termination 3.1 3.3 6.5 -2.5 0.4
Friendships satisfaction 0.0 0.0 0.0 -0.0 0.2
Qualifications: nursing, teaching 0.1 0.1 0.2 -0.1 0.5
Commuting to job workplace: Walk 1.1 1.2 1.8 0.8 -1.4
Eye problems/disorders: Cataract 0.9 1.1 1.1 -1.0 1.0
Mouth/teeth dental problems: Mouth ulcers 2.9 4.6 5.1 2.3 -2.0
Medication for cholesterol 2.8 4.2 4.9 1.9 -2.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.2 -0.3 0.4
Back pain experienced in last month 0.1 0.1 0.2 0.3 -0.4
Mineral and other dietary supplements 9.0 12.0 17.4 2.6 -4.2
Breast cancer (self-reported) 0.1 0.1 0.2 -0.0 0.4
Asthma (self-reported) 2.6 5.1 6.5 -2.5 1.9
Osteoporosis (self-reported) 3.5 4.4 5.7 2.4 -1.8
Osteoarthritis (self-reported) 0.0 0.1 0.1 0.3 0.1
Medication: Aspirin 0.2 0.3 0.5 -0.7 0.0
Medication: Gliclazide 0.3 0.4 0.7 -0.9 0.2
Illnesses of father: None of the above (group 1) 4.3 5.4 5.6 2.3 -2.4
Smoking status: Current 8.2 13.0 18.3 -4.3 2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.1 4.2 1.4 -2.1
Whole body water mass 0.8 4.7 6.7 -2.6 1.6
Leg predicted mass (right) 1.2 6.5 8.1 -2.9 2.2
Arm fat mass (left) 2.4 10.0 11.4 -2.9 3.4
Number of self-reported non-cancer illnesses 0.2 0.3 0.5 0.7 0.1
Average weekly champagne plus white wine intake 1.3 1.8 2.5 -1.6 1.1
Miserableness 7.0 12.1 13.2 3.6 -3.3
Guilty feelings 5.5 8.2 10.7 3.3 -2.4
Wears glasses or contact lenses 0.4 0.5 0.8 0.9 -0.4
Ever taken oral contraceptive pill 1.4 1.5 2.9 1.7 0.3
Hearing aid user 1.0 1.2 1.6 0.8 -1.3
Mother’s age at death 0.2 0.3 0.4 0.6 -0.4
Financial situation satisfaction 1.0 1.2 1.3 -1.1 1.0
Tinnitus: Yes, now most or all of the time 1.8 2.2 2.7 1.3 -1.6
Commuting to job workplace: Public transport 2.0 2.4 2.6 1.6 -1.5
Eye problems/disorders: Glaucoma 1.3 1.5 2.5 -0.8 1.6
Medication: Blood pressure 8.8 16.7 24.7 -3.0 5.0
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.4 0.4 0.6
Supplements: Fish oil (including cod liver oil) 6.4 8.3 13.2 -1.9 3.6
High cholesterol (Self-reported) 0.1 0.2 0.3 0.3 0.5
Medication: Bendroflumethiazide 7.6 11.6 11.6 -3.4 3.4
Medication: Paracetamol 1.1 1.7 2.7 1.6 -0.8
Medication: Lisinopril 1.2 1.5 1.8 -1.3 1.1
Medication: Atorvastatin 0.2 0.2 0.4 -0.1 0.6
Illnesses of father: High blood pressure 2.5 3.1 4.3 -1.4 2.1
Alcohol drinker status: Never 0.2 0.2 0.4 0.6 -0.2
Ever smoked 0.1 0.2 0.3 0.6 0.2
Basal metabolic rate 1.0 5.3 6.9 -2.6 1.9
Leg fat percentage (left) 2.0 7.2 9.6 -2.2 3.1
Arm fat-free mass (left) 0.8 4.0 6.8 -2.6 1.2
Number of operations (self-reported) 3.1 4.7 6.3 -1.7 2.5
Average weekly beer plus cider intake 7.1 10.2 14.6 3.8 -2.4
Irritability 12.8 21.6 22.0 4.7 -4.6
Risk taking 7.1 10.4 17.6 -4.2 1.8
Ever had prostate specific antigen (PSA) test 0.0 0.0 0.1 0.2 0.1
Fractured/broken bones in last 5 years 1.0 1.3 2.4 1.5 -0.5
Age started oral contraceptive pill 1.6 2.0 2.5 1.6 -1.2
Diastolic blood pressure, automated reading 7.3 22.6 25.1 -5.0 4.5
Ever depressed for a whole week 3.4 4.2 6.2 2.5 -1.5
Unable to work because of sickness or disability 2.2 2.8 3.1 -1.8 1.6
Commuting to job workplace: Cycle 0.4 0.5 1.0 -1.0 -0.1
Myopia 0.3 0.5 0.6 0.6 -0.8
Vascular/heart problems diagnosed by doctor 2.9 7.9 12.1 1.9 -3.5
Cholesterol lowering medication 0.2 0.3 0.5 -0.7 0.2
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.0 -0.1 1.0
Pain experienced in last month 0.3 0.6 1.1 -1.0 0.3
Supplements: Calcium 0.0 0.0 0.0 -0.0 0.1
Basal cell carcinoma (self-reported) 0.4 0.5 0.7 -0.5 0.8
Heart attack/myocardial infarction (self-reported) 0.2 0.3 0.5 0.7 -0.2
Deep venous thrombosis (DVT) (self-reported) 2.4 3.0 3.7 -1.5 1.9
Heart disease (siblings) 0.2 0.3 0.4 0.4 0.6
Alcohol drinker status: Previous 0.5 0.5 1.0 -1.0 -0.3
Pack years of smoking 0.7 1.1 1.6 -1.3 0.7
Impedance of whole body 3.5 17.8 25.3 5.0 -3.2
Leg fat mass (left) 2.3 9.1 10.4 -2.8 3.2
Arm predicted mass (left) 0.8 4.1 6.2 -2.5 1.4