TWAS hub - C8orf4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.052	0.0260	0.0280	0.038	0.002	0.022	0.009	0.030	1.7e-05	0.170	0.00094	0.028	0.00014
2	TCGA	Breast Invasive Carcinoma	0.014	0.0074	0.0058	0.006	0.004	0.006	NA	-0.001	1.5e-02	0.039	0.01900	NA	0.55000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Illnesses of mother	11.1	13.7	16.7	-4.1	-3.3
Diabetes (father)	6.0	7.4	8.8	2.5	3.0
Current tobacco smoking	4.7	7.7	9.6	2.4	3.1
Birth weight	4.6	9.9	12.7	-2.7	-3.6
Tinnitus: Yes, now most or all of the time	4.2	4.9	5.5	2.1	2.4
Hayfever/allergic rhinitis (self-reported)	4.1	5.4	7.8	-1.7	-2.8
Noisy workplace	4.0	4.9	8.1	2.8	1.3
Qualifications: None of the above	3.8	8.1	8.2	2.9	2.8
Smoking status: Current	3.8	6.1	7.9	2.1	2.8
Diabetes (mother)	3.6	4.5	7.3	2.7	1.3
LDL Cholesterol	3.4	5.4	7.8	-1.8	-2.8
Type 2 Diabetes (T2D) (2018)	3.2	6.1	11.0	-1.1	-3.3
Blood Red Count	2.9	27.8	54.5	-1.1	-7.4
Had major operations	2.9	3.4	5.8	2.4	1.0
Leg pain on walking	2.9	3.6	6.8	0.6	2.6
Rheumatoid Arthritis	2.8	3.9	3.9	2.0	2.0
Medication: Lansoprazole	2.8	3.2	6.3	2.5	0.4
Mouth/teeth dental problems	2.7	4.2	5.9	-1.5	-2.4
Eye problems/disorders: Cataract	2.7	3.1	4.9	-2.2	-1.1
Shortness of breath walking on level ground	2.6	3.1	5.6	2.4	0.8
Age at last live birth	2.6	3.8	4.1	-1.9	-2.0
Pack years adult smoking proportion	2.5	3.8	7.5	-0.2	2.7
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	4.7	-1.0	-2.2
Smoking status: Previous	2.5	3.7	5.2	-1.5	-2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	2.9	3.0	-1.7	-1.7
Pack years of smoking	2.5	3.6	7.2	-0.3	2.7
Severe depression (siblings)	2.4	2.6	3.9	-1.2	-2.0
Medication: Gliclazide	2.4	2.8	5.3	0.4	-2.3
Medication: Paracetamol	2.4	3.7	6.0	1.2	2.5
Ever depressed for a whole week	2.4	3.0	5.6	0.6	-2.4
Number of treatments/medications taken	2.3	4.2	6.5	1.4	2.5
Birth weight of first child	2.3	4.1	6.5	-2.6	-1.3
Medication: Paracetamol	2.3	3.8	6.3	1.1	2.5
Ulcerative Colitis	2.2	3.1	5.1	-1.1	-2.3
Medication: Levothyroxine sodium	2.2	3.8	4.8	-1.7	-2.2
Qualifications: nursing, teaching	2.2	3.4	3.8	-1.9	-1.7
Diastolic blood pressure, automated reading	2.2	6.8	9.4	2.1	3.1
Myopia	2.2	3.2	5.5	2.3	1.0
Qualifications: College or University degree	2.1	6.6	7.0	-2.6	-2.5
Serious illness, injury or assault to yourself	2.0	2.4	4.0	1.0	2.0
Qualifications: A levels/AS levels or equivalent	2.0	4.4	7.5	-1.1	-2.7
Overall health rating	2.0	4.2	5.7	1.6	2.4
Sitting height	1.9	13.4	21.7	-2.2	-4.7
Had other major operations	1.9	2.3	3.3	-1.8	-1.1
Glaucoma (self-reported)	1.9	2.2	2.7	1.3	1.6
Vitamin and mineral supplements	1.8	2.5	3.1	-1.4	-1.8
Mouth/teeth dental problems: Dentures	1.8	3.1	4.0	1.5	2.0
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.7	-1.0	-2.2
Pain experienced in last month	1.8	3.1	5.0	-1.1	-2.2
Age at first live birth	1.7	2.9	5.1	-0.9	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.9	3.7	-0.2	-1.9
Pain type(s) experienced in last month: Hip pain	1.7	2.1	3.9	0.5	2.0
Systolic Blood Pressure	1.6	8.2	14.9	1.2	3.9
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	3.8	-1.6	-1.9
High blood pressure (siblings)	1.6	2.3	4.0	2.0	0.7
Number of full brothers	1.6	2.0	3.6	0.6	1.9
Number of children fathered	1.6	1.8	3.5	-0.3	-1.9
Heart disease (mother)	1.6	1.9	2.7	1.6	1.1
Blood Platelet Count	1.5	17.6	32.4	1.7	5.7
Respiratory disease	1.5	3.4	5.5	2.4	1.1
Commuting to job workplace: Walk	1.5	1.6	2.5	-0.8	-1.6
Average weekly champagne plus white wine intake	1.5	2.0	2.9	-1.7	-1.1
Wears glasses or contact lenses	1.5	1.7	2.3	1.0	1.5
Ever smoked	1.5	2.6	3.2	-1.8	-1.4
Coronary Artery Disease (CAD)	1.4	1.7	1.7	-1.3	-1.3
High blood pressure	1.4	4.0	5.2	2.3	1.6
Past tobacco smoking	1.4	2.6	3.1	1.5	1.8
Medication for pain relief, constipation, heartburn	1.4	2.5	3.5	-1.2	-1.9
High cholesterol (Self-reported)	1.4	2.4	3.5	-1.9	-1.2
Prospective memory result	1.3	1.6	2.8	0.6	1.7
Gout (self-reported)	1.3	1.8	3.5	-1.9	-0.1
Hearing aid user	1.3	1.5	2.3	0.8	1.5
Schizophrenia vs Biploar Disorder	1.2	1.5	3.0	-0.2	1.7
Medication for hormone replacement therapy	1.2	1.3	2.5	-1.6	0.4
High blood pressure (mother)	1.2	1.6	2.7	1.6	0.8
Illnesses of siblings: Diabetes	1.2	1.4	2.6	1.6	-0.5
Osteoporosis (self-reported)	1.2	1.5	1.9	1.0	1.4
Ulcerative Colitis (UC)	1.1	2.1	4.2	-0.2	-2.0
Hypothyroidism (self reported)	1.1	2.6	3.6	-1.9	-1.3
Medication: Metformin	1.1	1.5	3.0	0.3	-1.7
Length of working week for main job	1.1	1.2	2.4	0.0	1.5
Tense / ‘highly strung’	1.1	1.8	2.9	0.9	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.0	-1.4	0.7
Friendships satisfaction	1.1	1.4	1.9	-0.9	-1.4
Alcohol drinker status: Never	1.1	1.3	2.2	-0.6	1.5
Fractured/broken bones in last 5 years	1.1	1.4	2.1	1.5	-0.8
Systolic blood pressure, automated reading	1.0	3.0	5.4	0.8	2.3
Illnesses of siblings	1.0	1.4	2.6	-1.6	-0.3
Breastfed as a baby	1.0	1.2	2.0	-0.7	-1.4
Exposure to tobacco smoke outside home	1.0	1.4	1.9	0.9	1.4
Wheeze or whistling in the chest in last year	1.0	1.9	2.9	1.7	0.9
Emphysema/chronic bronchitis	1.0	1.2	2.3	-0.1	-1.5
Medication: Ibuprofen	1.0	1.2	2.3	0.2	1.5
Family relationship satisfaction	1.0	1.3	2.4	-0.4	-1.5
Supplements: Vitamin C	1.0	1.1	1.5	1.2	0.9
Hypertension (Self-reported)	1.0	2.7	4.5	2.1	1.0
Long-standing illness, disability or infirmity	1.0	1.5	1.7	1.3	1.2
Diabetes diagnosed by doctor	1.0	1.7	3.4	-0.0	-1.8
Ever had prostate specific antigen (PSA) test	1.0	1.2	1.5	-0.9	-1.2
Vascular/heart problems diagnosed by doctor	1.0	2.6	2.7	-1.6	-1.7
Alzheimer’s Disease (in father)	0.9	1.0	2.0	1.4	0.3
Medication: Co-codamol	0.9	1.0	1.8	1.3	0.5
Medication: Atenolol	0.9	1.1	2.1	1.5	0.0
Financial difficulties in last 2 years	0.9	1.2	2.0	-1.4	-0.6
Pain all over the body in last month	0.9	0.9	1.2	0.8	1.1
Falls in the last year	0.9	1.2	1.7	-0.8	-1.3
Happiness	0.9	1.0	1.8	-0.5	-1.3
Eye problems/disorders: None of the above	0.9	1.1	2.1	1.4	0.4
Migraine (self-reported)	0.9	1.1	2.1	1.5	0.0
Number of full sisters	0.9	1.1	1.3	-1.1	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	2.5	0.6	1.6
Average weekly beer plus cider intake	0.9	1.3	2.2	0.6	1.5
Age started oral contraceptive pill	0.9	1.2	2.2	0.4	1.5
Unable to work because of sickness or disability	0.9	1.1	2.1	-0.3	1.5
Commuting to job workplace: Cycle	0.9	1.1	1.6	-0.9	-1.2
Worry (Nagel 2018)	0.8	1.7	2.5	-1.6	-0.9
Lupus	0.8	1.2	1.5	-0.9	-1.2
Hearing difficulty/problems with background noise	0.8	1.3	2.0	1.4	0.7
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	1.5	0.6	-1.2
Diabetes (self-reported)	0.8	1.2	2.3	-0.1	-1.5
Worrier / anxious feelings	0.8	1.5	2.2	-0.9	-1.5
Standing height	0.8	8.3	14.9	-1.4	-3.9
Guilty feelings	0.8	1.3	1.5	-1.0	-1.2
Ever taken oral contraceptive pill	0.8	0.9	1.7	1.3	0.3
Basal cell carcinoma (self-reported)	0.8	1.0	1.1	-1.1	-0.9
Major Depression (MDD)	0.7	0.8	1.5	-0.3	-1.2
Medication: Simvastatin	0.7	1.0	1.2	-0.9	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.5	1.2	0.3
Leg fat percentage (right)	0.7	2.5	2.8	1.5	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.2	-0.8	-1.1
Health satisfaction	0.7	1.0	1.1	0.9	1.0
Medication: Allopurinol	0.7	0.9	1.7	-0.3	1.3
Mineral and other dietary supplements	0.7	1.0	2.0	0.1	-1.4
Commuting to job workplace: Public transport	0.7	0.8	1.4	-0.4	-1.2
Leg fat percentage (left)	0.7	2.4	2.9	1.4	1.7
Verbal and Numeric Reasoning (VNR)	0.6	1.3	1.9	-0.8	-1.4
Waist Hip Ratio (WHR)	0.6	2.9	3.1	-1.6	-1.8
Smoking Status	0.6	1.4	1.9	1.0	1.4
Townsend deprivation index at recruitment	0.6	0.8	1.4	1.2	0.5
Average weekly fortified wine intake	0.6	0.7	0.9	0.9	0.7
Maternal smoking around birth	0.6	0.9	1.8	1.3	0.0
Qualifications: CSEs or equivalent	0.6	0.8	1.5	0.3	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.5	-0.0	1.2
Depression (self-reported)	0.6	0.7	0.7	-0.8	-0.8
Pulse wave peak to peak time	0.6	0.7	0.9	-0.9	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.5	-1.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	0.8	0.9	-0.9
Comparative height size at age 10	0.6	3.2	5.6	0.9	-2.4
Back pain experienced in last month	0.6	0.9	1.4	0.6	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	1.6	1.3	0.8
Irritability	0.6	1.1	1.4	1.2	0.9
Cholesterol lowering medication	0.6	0.9	1.0	-1.0	-0.9
Irritable Bowel Disease (IBD)	0.5	1.2	2.3	0.2	-1.5
Body Mass Index (BMI) (2010)	0.5	0.7	1.1	0.6	1.1
Primary Biliary Cirrhosis	0.5	0.7	1.3	-1.1	0.2
Triglycerides	0.5	0.8	0.8	-0.9	-0.9
Blood Eosinophil Count	0.5	3.5	6.8	0.4	2.6
Allergy or Eczema	0.5	1.4	2.7	-0.3	-1.6
Cardiovascular Disease	0.5	1.7	1.7	1.3	1.3
Lung FVC	0.5	2.4	2.8	1.7	1.4
Hand grip strength (left)	0.5	1.3	2.3	-0.6	-1.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	0.7	0.8	-0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.5	-0.7	-0.7
Supplements: Glucosamine	0.5	0.7	1.3	-0.1	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	-0.1	1.1
Alcohol usually taken with meals	0.5	0.8	1.5	-0.4	-1.2
Hair/balding pattern: Pattern 2	0.5	0.7	1.3	-1.1	-0.3
Medication: Ramipril	0.5	0.7	1.1	0.4	-1.1
Arm fat percentage (right)	0.5	1.8	2.0	1.4	1.3
Headache pain in last month	0.5	0.9	1.4	1.2	0.7
Worry too long after embarrassment	0.5	0.9	1.4	-1.2	0.6
Medication: Blood pressure	0.5	0.8	1.4	1.2	0.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	0.7	-0.8	-0.8
Average weekly red wine intake	0.5	0.8	0.8	-0.8	-0.9
Handedness (chirality/laterality): Left-handed	0.5	0.7	1.3	0.0	-1.1
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.2	-0.1	1.1
Medication: Bendroflumethiazide	0.5	0.7	0.9	0.7	1.0
Supplements: Calcium	0.5	0.5	0.7	0.9	-0.5
Heart disease (siblings)	0.5	0.6	0.7	0.8	-0.7
Bipolar Disorder (2018)	0.4	0.6	1.3	-0.1	-1.1
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.2	0.1	-1.5
HbA1C	0.4	0.4	0.7	0.8	-0.3
Blood White Count	0.4	3.0	5.9	0.4	2.4
Height	0.4	7.9	15.7	-0.3	-4.0
Hearing difficulty/problems: Yes	0.4	0.7	0.7	0.9	0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	0.4	0.9
Supplements: Zinc	0.4	0.5	0.8	0.9	0.4
Hand grip strength (right)	0.4	1.0	1.5	-0.7	-1.2
Multivitamins +/- minerals	0.4	0.6	0.6	0.8	0.7
Had menopause	0.4	0.5	1.0	-0.1	1.0
Hip circumference	0.4	1.9	3.3	1.8	0.7
Father’s age at death	0.4	0.6	0.7	-0.9	-0.7
Pulse rate	0.4	0.7	1.2	1.1	0.4
Asthma	0.4	0.7	1.3	1.1	0.4
Peak expiratory flow (PEF)	0.4	0.9	1.4	-0.7	-1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.8	0.9	0.6
Body fat percentage	0.4	1.4	1.8	1.3	1.0
Comparative body size at age 10	0.4	1.0	2.0	1.4	0.2
Neck or shoulder pain in last month	0.4	0.6	1.0	0.5	1.0
Angina (self-reported)	0.4	0.5	0.7	-0.8	-0.5
Leg fat mass (right)	0.4	1.4	1.8	1.4	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.0	1.0	-0.7
Loneliness, isolation	0.4	0.5	0.9	-1.0	-0.3
Breast cancer (self-reported)	0.4	0.5	0.5	-0.7	-0.7
Asthma (self-reported)	0.4	0.8	1.5	1.2	0.4
Miserableness	0.4	0.8	1.3	-1.2	0.5
Mother’s age at death	0.4	0.5	0.9	-0.4	0.9
Depressed Affect (Nagel 2018)	0.3	0.5	0.8	-0.5	0.9
Depression (Nagel 2018)	0.3	0.4	0.7	-0.3	-0.8
Alzheimer’s Disease (in mother)	0.3	0.3	0.6	-0.8	-0.0
Reaction Time	0.3	0.6	1.1	-0.5	1.0
Ovarian Cancer	0.3	0.4	0.7	-0.3	-0.8
Bipolar Disorder (2011)	0.3	0.3	0.4	-0.5	-0.6
HDL Cholesterol	0.3	0.4	0.8	-0.2	-0.9
Chronotype (morning person)	0.3	0.7	1.2	0.4	1.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	0.4	0.8
Fed-up feelings	0.3	0.5	0.6	0.8	0.6
Taking other prescription medications	0.3	0.4	0.5	0.5	0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	-0.7	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	0.9	1.0	0.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	0.8	-0.6	-0.9
Body mass index (BMI)	0.3	1.3	1.3	1.1	1.2
Heart attack	0.3	0.3	0.4	0.7	0.5
Trunk fat-free mass	0.3	1.8	3.4	-0.5	-1.9
Alcohol intake versus 10 years previously	0.3	0.4	0.5	0.7	0.6
Lung cancer (father)	0.3	0.4	0.4	-0.6	-0.6
Pulse wave Arterial Stiffness index	0.3	0.4	0.6	0.7	0.5
Trunk predicted mass	0.3	1.7	3.1	-0.6	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.9	1.0	0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.0	-1.0	-0.3
Medication: Seretide 50 evohaler	0.3	0.3	0.6	0.0	-0.8
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.5	-0.2	0.7
Whole body fat-free mass	0.3	1.5	3.0	-0.2	-1.7
Leg fat-free mass (right)	0.3	1.5	3.0	0.1	-1.7
Arm fat percentage (left)	0.3	1.4	1.5	1.2	1.1
Mood swings	0.3	0.6	0.7	0.6	0.9
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	-0.9	-0.3
Whole body water mass	0.3	1.7	3.4	-0.3	-1.8
Leg predicted mass (right)	0.3	1.4	2.8	0.1	-1.7
Medication: Blood pressure	0.3	0.6	0.7	0.7	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.4	0.6	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.7	0.8	0.2
Leg fat mass (left)	0.3	1.2	1.5	1.2	1.0
Neuroticism (Nagel 2018)	0.2	0.6	1.1	-1.1	0.0
Prostate Cancer	0.2	0.3	0.4	-0.5	-0.6
Crohns Disease (2012)	0.2	0.3	0.5	-0.7	0.1
Mean Putamen Volume	0.2	0.3	0.5	0.3	-0.7
Fasting Glucose	0.2	0.2	0.3	-0.3	-0.5
Neuroticism	0.2	0.6	1.0	-1.0	0.3
Tanning	0.2	2.4	2.7	1.6	1.4
Average weekly spirits intake	0.2	0.2	0.3	-0.5	0.5
Sensitivity / hurt feelings	0.2	0.3	0.3	-0.6	0.5
Angina	0.2	0.3	0.4	-0.7	-0.4
Leg fat-free mass (left)	0.2	1.2	2.3	0.3	-1.5
Trunk fat percentage	0.2	0.9	1.7	1.3	0.4
Age when periods started (menarche)	0.2	0.4	0.7	0.9	0.3
Stomach or abdominal pain in last month	0.2	0.3	0.5	-0.2	0.7
Leg predicted mass (left)	0.2	1.3	2.5	0.2	-1.6
Allergy	0.2	0.6	1.1	0.2	1.1
Neuroticism score	0.2	0.4	0.7	-0.8	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.4	-0.6	0.3
Hair/balding pattern: Pattern 3	0.2	0.2	0.3	0.4	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	0.6	0.7	-0.6
Arm fat mass (right)	0.2	0.7	1.1	1.1	0.5
Exposure to tobacco smoke at home	0.2	0.3	0.5	0.1	0.7
Pulse wave reflection index	0.2	0.3	0.3	0.6	-0.4
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	-0.1	0.6
Loud music exposure frequency	0.2	0.3	0.4	-0.4	0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.4	0.5	0.6
Blood clot in the leg (DVT)	0.2	0.3	0.3	0.6	-0.5
Medication: Amlodipine	0.2	0.2	0.4	0.6	-0.3
Whole body fat mass	0.2	0.7	1.3	1.1	0.4
Arm predicted mass (right)	0.2	0.9	1.4	-0.6	-1.2
Pulse rate, automated reading	0.2	0.5	0.9	0.2	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.3	0.6	-0.4
Medication for cholesterol	0.2	0.3	0.5	0.7	-0.3
Medication: Aspirin	0.2	0.3	0.4	0.6	0.5
Number of self-reported non-cancer illnesses	0.2	0.3	0.5	0.5	0.7
Financial situation satisfaction	0.2	0.2	0.3	0.3	-0.6
Medication: Lisinopril	0.2	0.2	0.5	0.7	-0.1
Illnesses of father: High blood pressure	0.2	0.2	0.3	-0.6	0.3
Basal metabolic rate	0.2	1.1	2.1	0.1	-1.4
Number of operations (self-reported)	0.2	0.3	0.5	0.7	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.2	0.2	-0.4	-0.3
Schizophrenia (2018)	0.1	0.1	0.3	-0.5	0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	-0.1	0.4
Crohns Disease (2017)	0.1	0.3	0.6	0.8	0.2
Age at First Birth	0.1	0.1	0.1	-0.4	-0.1
Schizophrenia (2014)	0.1	0.3	0.4	-0.4	0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	-0.3	0.3
Heel T-Score	0.1	0.5	0.6	0.6	-0.7
BMI	0.1	0.4	0.5	-0.5	0.7
Relative age of first facial hair	0.1	0.2	0.4	0.1	-0.7
Impedance of leg (right)	0.1	0.3	0.7	0.0	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.2	-0.4	-0.4
Relative age voice broke	0.1	0.2	0.4	-0.2	0.6
Chronic bronchitis/emphysema (father)	0.1	0.2	0.3	0.2	-0.5
Impedance of leg (left)	0.1	0.4	0.7	-0.1	0.9
Trunk fat mass	0.1	0.5	1.0	1.0	-0.2
Forced vital capacity (FVC)	0.1	0.5	0.9	0.2	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.4	0.6	0.5
Fluid intelligence score	0.1	0.1	0.2	-0.1	-0.5
Weight	0.1	0.4	0.5	0.6	-0.7
Time employed in main current job	0.1	0.1	0.2	0.0	0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.6	0.1	-0.8
Impedance of arm (left)	0.1	0.5	0.6	-0.5	-0.8
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.5	0.3
Forced vital capacity (FVC), Best measure	0.1	0.3	0.4	0.5	-0.6
Arm fat-free mass (right)	0.1	0.5	1.1	-0.1	-1.0
Medication: Omeprazole	0.1	0.1	0.2	0.4	-0.3
Mean time to correctly identify matches	0.1	0.2	0.2	-0.4	0.5
Alcohol intake frequency.	0.1	0.3	0.6	-0.0	0.8
Suffer from ‘nerves’	0.1	0.2	0.4	-0.6	0.1
Chest pain or discomfort	0.1	0.1	0.2	0.0	0.5
Medication: Aspirin	0.1	0.1	0.1	0.4	0.1
Knee pain experienced in last month	0.1	0.1	0.1	-0.3	0.3
Illnesses of father: Heart disease	0.1	0.1	0.1	0.2	0.4
Ever had bowel cancer screening	0.1	0.2	0.3	0.6	-0.1
Osteoarthritis (self-reported)	0.1	0.2	0.2	0.5	-0.3
Arm fat mass (left)	0.1	0.3	0.4	0.6	0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.0	0.4
Arm fat-free mass (left)	0.1	0.7	1.4	-0.2	-1.2
Risk taking	0.1	0.1	0.1	-0.4	0.3
Alcohol drinker status: Previous	0.1	0.1	0.2	0.5	0.1
Arm predicted mass (left)	0.1	0.5	1.0	-0.0	-1.0
Breast Cancer	0.0	0.0	0.1	0.1	0.3
Neuroticism (2016)	0.0	0.1	0.1	0.4	0.1
Lung FEV1/FVC ratio	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.7	0.7	-0.8	-0.9
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.1	0.2	0.1
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	0.2	-0.2
Waist circumference	0.0	0.1	0.1	0.4	-0.0
Number of incorrect matches in round	0.0	0.1	0.1	-0.2	0.2
Nervous feelings	0.0	0.1	0.1	-0.4	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.1	-0.3	-0.0
Impedance of arm (right)	0.0	0.2	0.4	-0.2	-0.6
Number of live births	0.0	0.0	0.0	0.1	-0.0
Medication: Cholesterol lowering	0.0	0.1	0.1	0.2	-0.3
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.3	0.3
Medication: Atorvastatin	0.0	0.0	0.1	-0.3	-0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.0	0.2	0.2
Impedance of whole body	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

C8orf4

Models

Trait associations