TWAS hub - C8orf40

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0670	0.0310	4.4e-08	0.088	0.082	0.073	NA	0.077	6.7e-08	1.8e-07	9.5e-07	NA	4.3e-07
2	TCGA	Breast Invasive Carcinoma	0.0323	0.0171	3.8e-07	0.031	0.035	0.032	NA	0.033	4.0e-07	9.7e-08	2.8e-07	NA	1.8e-07
3	TCGA	Cervical Squamous Cell Carcinoma	0.0860	0.0510	6.6e-05	0.056	0.078	0.059	NA	0.056	1.0e-03	1.2e-04	7.5e-04	NA	1.0e-03
4	TCGA	Colon Adenocarcinoma	0.1390	0.0610	9.5e-11	0.144	0.165	0.164	NA	0.175	1.1e-08	8.1e-10	9.2e-10	NA	2.3e-10
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.0543	0.0304	5.4e-06	0.051	0.055	0.056	NA	0.052	1.8e-06	8.2e-07	5.9e-07	NA	1.6e-06
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.1220	0.0457	0.0e+00	0.147	0.161	0.164	NA	0.160	2.9e-16	9.7e-18	4.8e-18	NA	1.4e-17
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1800	0.0700	3.9e-15	0.286	0.261	0.265	NA	0.269	1.0e-16	3.8e-15	2.0e-15	NA	1.2e-15
8	TCGA	Brain Lower Grade Glioma	0.0535	0.0229	9.2e-10	0.080	0.081	0.089	NA	0.086	1.9e-09	1.9e-09	2.9e-10	NA	5.5e-10
9	TCGA	Liver Hepatocellular Carcinoma	0.0710	0.0420	5.0e-04	0.103	0.050	0.067	NA	0.069	1.4e-05	2.3e-03	4.3e-04	NA	3.6e-04
10	TCGA	Lung Adenocarcinoma	0.0511	0.0210	1.1e-11	0.099	0.106	0.097	NA	0.104	1.2e-11	2.5e-12	1.9e-11	NA	3.8e-12
11	TCGA	Lung Squamous Cell Carcinoma	0.0424	0.0214	2.2e-06	0.028	0.040	0.031	NA	0.028	3.6e-04	1.9e-05	1.6e-04	NA	3.5e-04
12	TCGA	Pancreatic Adenocarcinoma	0.2210	0.1220	2.4e-05	0.074	0.088	0.042	NA	0.061	5.2e-04	1.6e-04	7.2e-03	NA	1.5e-03
13	TCGA	Pheochromocytoma and Paraganglioma	0.0560	0.0360	6.5e-03	0.068	0.053	0.055	NA	0.061	1.1e-03	3.6e-03	3.2e-03	NA	1.9e-03
14	TCGA	Prostate Adenocarcinoma	0.0298	0.0218	2.0e-03	0.016	0.021	0.015	NA	0.011	7.7e-03	2.7e-03	9.6e-03	NA	2.0e-02
15	TCGA	Soft Tissue Sarcoma	0.1460	0.0590	3.8e-10	0.125	0.151	0.146	NA	0.133	7.5e-08	2.8e-09	5.6e-09	NA	2.9e-08
16	TCGA	Skin Cutaneous Melanoma	0.1050	0.0600	1.1e-03	0.057	0.020	0.001	NA	0.006	1.3e-02	9.4e-02	3.0e-01	NA	2.2e-01
17	TCGA	Stomach Adenocarcinoma	0.0540	0.0440	1.5e-03	0.037	0.017	0.010	NA	0.020	9.8e-04	2.0e-02	5.7e-02	NA	1.2e-02
18	TCGA	Testicular Germ Cell Tumors	0.1790	0.0900	6.4e-07	0.199	0.199	0.198	NA	0.204	1.4e-07	1.4e-07	1.5e-07	NA	9.4e-08
19	TCGA	Thyroid Carcinoma	0.1200	0.0400	0.0e+00	0.291	0.274	0.283	NA	0.285	1.5e-28	1.0e-26	9.8e-28	NA	6.7e-28

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Blood Red Count	18.3	176.5	216.1	-14.0	-14.4	-12.3	-12.5	-12.9	-12.7	-13.1	-12.9	-13.7	-13.1	-12.6	-13.7	-13.0	-14.5	-14.7	-12.9	-13.0	-13.0	-13.1
HbA1C	11.3	12.5	14.3	3.4	3.1	3.7	3.6	3.7	3.8	3.6	3.7	3.7	3.7	3.7	3.4	3.4	3.1	3.0	3.8	3.5	3.7	3.6
Hearing aid user	9.5	10.8	13.9	-3.3	-3.3	-3.1	-3.3	-3.4	-3.2	-3.1	-3.1	-3.7	-3.2	-3.2	-3.2	-3.3	-3.4	-3.4	-3.2	-3.3	-3.4	-3.1
Crohns Disease (2012)	8.4	13.5	21.8	2.9	2.6	4.3	4.0	3.8	4.7	3.7	3.9	3.4	4.0	4.5	2.9	4.2	3.1	2.6	4.4	0.0	4.0	3.9
Wheeze or whistling in the chest in last year	6.6	11.7	14.8	3.0	2.3	3.8	3.7	2.8	3.6	3.7	3.6	3.4	3.8	3.7	3.4	3.5	2.6	2.6	3.7	3.6	3.7	3.7
Deep venous thrombosis (DVT) (self-reported)	6.5	8.3	11.3	-2.7	-2.7	-2.9	-3.0	-3.4	-3.1	-2.8	-2.8	-2.7	-2.9	-3.0	-2.5	-3.0	-2.8	-2.6	-3.0	-3.1	-2.9	-2.8
Crohns Disease (2017)	6.0	13.2	17.4	3.1	2.8	4.0	3.7	3.9	4.1	3.6	3.8	3.2	3.9	4.2	3.3	3.8	2.9	2.9	4.0	3.9	3.7	3.7
Unable to work because of sickness or disability	5.8	7.5	8.7	2.7	2.3	2.9	2.9	2.6	2.9	3.0	2.9	2.7	2.9	2.8	2.7	2.6	2.5	2.4	2.9	2.7	2.8	2.9
Qualifications: College or University degree	5.5	17.3	22.2	-3.4	-2.8	-4.6	-4.4	-4.1	-4.5	-4.2	-4.1	-4.1	-4.5	-4.7	-3.7	-4.6	-3.3	-3.2	-4.6	-4.6	-4.6	-4.2
Irritable Bowel Disease (IBD)	5.3	12.7	16.2	3.1	2.9	3.8	3.6	4.0	3.9	3.5	3.5	3.3	3.7	4.0	3.2	3.7	3.1	3.0	3.9	3.9	3.6	3.5
Alcohol usually taken with meals	5.2	8.3	11.7	-2.5	-1.6	-3.4	-3.1	-2.2	-3.0	-3.2	-3.2	-2.6	-3.3	-3.3	-3.0	-3.0	-2.0	-2.0	-3.2	-2.9	-3.1	-3.2
Average weekly spirits intake	4.9	6.1	7.4	2.5	2.3	2.4	2.6	2.3	2.3	2.3	2.4	2.7	2.5	2.5	2.5	2.6	2.5	2.4	2.5	2.6	2.6	2.3
Blood clot in the leg (DVT)	4.8	6.2	8.9	-2.3	-2.4	-2.4	-2.6	-3.0	-2.7	-2.4	-2.3	-2.4	-2.5	-2.5	-2.1	-2.6	-2.6	-2.3	-2.6	-2.7	-2.5	-2.3
Medication for hormone replacement therapy	4.7	5.3	6.4	2.2	2.0	2.5	2.3	2.1	2.5	2.5	2.5	2.1	2.4	2.5	2.3	2.3	2.0	2.0	2.5	2.3	2.3	2.5
Reason for reducing amount of alcohol drunk: Health precaution	4.7	5.5	7.0	-2.4	-2.0	-2.4	-2.5	-1.9	-2.1	-2.3	-2.3	-2.6	-2.5	-2.2	-2.6	-2.4	-2.2	-2.4	-2.2	-2.4	-2.5	-2.2
Exposure to tobacco smoke outside home	4.6	6.2	7.0	2.5	2.2	2.6	2.5	2.2	2.6	2.6	2.6	2.4	2.6	2.6	2.5	2.5	2.4	2.3	2.6	2.4	2.5	2.5
Bipolar Disorder (2011)	4.4	4.3	8.4	-2.6	-2.9	-1.6	-1.8	-2.2	-1.6	-1.9	-2.0	-2.2	-1.8	-1.5	-2.4	-1.9	-2.8	-2.8	-1.7	0.0	-1.8	-2.2
Other serious medical condition/disability diagnosed by doctor	4.4	5.7	8.7	2.2	2.4	2.4	2.0	2.9	2.5	2.2	2.1	2.1	2.4	2.7	2.2	2.5	2.5	2.7	2.4	2.4	2.2	2.3
Qualifications: None of the above	4.4	9.5	11.9	2.8	2.5	3.3	3.0	3.2	3.3	3.0	3.1	2.9	3.2	3.5	2.9	3.3	2.7	2.6	3.4	3.1	3.2	3.1
Alcohol drinker status: Never	4.3	5.2	9.2	-2.6	-3.0	-1.7	-1.9	-2.7	-1.9	-2.1	-1.9	-2.3	-2.0	-1.9	-2.3	-2.1	-3.0	-3.0	-2.0	-2.1	-2.0	-2.1
Qualifications: nursing, teaching	4.2	6.5	8.1	-2.4	-1.9	-2.8	-2.8	-2.1	-2.8	-2.7	-2.8	-2.6	-2.8	-2.6	-2.5	-2.5	-2.1	-1.9	-2.8	-2.5	-2.8	-2.7
Eye problems/disorders: None of the above	4.1	4.7	6.4	-1.8	-1.5	-2.4	-2.3	-2.2	-2.5	-2.2	-2.2	-1.8	-2.3	-2.5	-1.8	-2.5	-1.9	-1.6	-2.4	-2.5	-2.3	-2.3
Overall health rating	4.1	8.8	11.3	2.6	2.5	3.2	2.9	3.3	3.2	2.9	2.9	2.7	3.1	3.4	2.7	3.2	2.7	2.7	3.2	3.2	3.1	3.0
Back pain experienced in last month	4.1	6.0	8.1	2.2	1.9	2.6	2.6	2.2	2.6	2.8	2.7	2.1	2.6	2.5	2.3	2.5	2.1	1.9	2.7	2.5	2.6	2.8
Long-standing illness, disability or infirmity	4.0	6.1	9.2	2.1	2.0	2.6	2.4	3.0	2.6	2.3	2.2	2.4	2.6	2.9	2.1	2.7	2.3	2.3	2.6	2.7	2.6	2.3
Heart disease (siblings)	4.0	4.9	6.3	2.0	1.5	2.5	2.5	1.6	2.4	2.3	2.3	2.4	2.4	2.4	2.1	2.4	1.8	1.6	2.4	2.3	2.5	2.3
Bipolar Disorder (2018)	3.9	6.2	14.6	-3.3	-3.8	-1.5	-1.9	-2.5	-1.7	-2.3	-2.2	-2.6	-2.1	-1.5	-3.0	-2.1	-3.5	-3.7	-1.8	0.0	-2.0	-2.4
Guilty feelings	3.9	5.9	7.1	2.4	2.1	2.6	2.4	2.4	2.6	2.6	2.7	2.3	2.5	2.5	2.5	2.2	2.2	2.3	2.5	2.3	2.4	2.5
Townsend deprivation index at recruitment	3.7	5.3	6.4	2.3	2.0	2.5	2.2	2.1	2.3	2.4	2.5	2.2	2.5	2.5	2.5	2.2	1.9	2.2	2.4	2.2	2.3	2.3
Fed-up feelings	3.7	6.7	7.8	2.3	2.4	2.5	2.5	2.7	2.7	2.8	2.5	2.6	2.6	2.6	2.2	2.6	2.6	2.4	2.7	2.7	2.7	2.7
Depressed Affect (Nagel 2018)	3.6	7.5	9.1	2.6	2.6	2.7	2.7	2.7	2.9	3.0	2.9	2.5	2.8	2.7	2.6	2.7	2.7	2.6	2.8	2.7	2.6	3.0
Medication: Seretide 50 evohaler	3.5	4.0	5.4	2.0	2.2	1.7	1.9	1.9	1.7	2.0	1.7	2.3	1.9	1.8	2.0	2.0	2.3	2.3	1.9	2.1	2.0	2.0
Alzheimer’s Disease (including proxy)	3.4	4.9	6.8	-2.1	-1.6	-2.6	-1.7	-1.9	-2.6	-2.4	-2.2	-2.2	-2.4	-2.6	-2.1	-2.6	-1.9	-1.9	-2.4	-1.3	-2.5	-2.4
Bipolar Disorder or Schizophrenia	3.3	8.1	16.2	-3.5	-4.0	-2.3	-2.3	-3.3	-2.5	-2.5	-2.7	-3.0	-2.5	-2.3	-3.2	-2.5	-3.7	-3.9	-2.4	0.0	-2.5	-2.6
Serious illness, injury or assault to yourself	3.3	3.9	6.3	2.5	2.5	1.7	1.7	1.7	1.8	2.0	2.0	2.1	1.9	1.6	2.3	1.6	2.4	2.5	1.7	1.6	1.8	2.0
Chest pain or discomfort	3.3	4.7	6.1	2.0	2.2	2.0	1.9	2.5	2.2	2.1	1.9	2.3	2.1	2.3	2.0	2.3	2.3	2.4	2.1	2.2	2.2	2.1
Diabetes diagnosed by doctor	3.3	5.3	6.0	2.2	2.1	2.3	2.4	2.4	2.3	2.3	2.3	2.4	2.4	2.4	2.2	2.4	2.2	2.1	2.4	2.4	2.5	2.2
Number of full brothers	3.2	4.0	7.3	2.2	2.6	1.8	1.6	2.7	1.9	1.7	1.8	2.0	1.8	2.0	2.0	1.8	2.3	2.5	1.8	1.7	1.8	1.7
Mouth/teeth dental problems: Loose teeth	3.2	3.8	5.6	1.7	0.9	2.3	2.4	0.7	2.1	2.3	2.2	1.9	2.3	2.0	2.0	2.1	1.4	1.2	2.2	2.1	2.2	2.3
Maternal smoking around birth	3.1	4.4	6.8	1.2	0.7	2.5	2.3	1.6	2.4	2.5	2.1	1.7	2.4	2.6	1.5	2.4	1.3	0.9	2.6	2.4	2.4	2.6
Ulcerative Colitis (UC)	2.9	5.5	9.1	2.1	2.3	2.2	2.2	3.0	2.4	2.2	2.1	2.3	2.3	2.5	1.9	2.5	2.4	2.3	2.5	2.6	2.4	2.2
Eye problems/disorders: Cataract	2.9	3.4	5.0	1.7	1.6	1.9	1.9	2.2	2.0	1.7	1.9	1.6	1.9	2.0	1.6	2.0	1.7	1.6	2.0	2.1	1.8	1.7
Coronary Artery Disease (CAD)	2.5	3.0	5.9	1.1	0.9	2.2	1.9	1.7	2.4	1.7	1.7	1.7	2.0	2.4	1.1	2.1	1.2	1.0	2.2	0.0	2.0	1.6
Mouth/teeth dental problems: Dentures	2.5	4.3	5.4	2.0	2.1	2.0	1.9	1.9	2.0	2.0	1.9	2.1	2.1	2.0	2.1	2.2	2.3	2.3	2.0	2.2	2.1	2.0
Irritability	2.4	4.1	6.2	1.4	1.4	2.1	2.0	1.9	2.3	2.3	1.7	2.0	2.1	2.4	1.4	2.3	1.9	1.6	2.3	2.5	2.2	2.2
Smoking Status	2.3	5.5	8.1	1.8	1.2	2.9	2.6	1.6	2.7	2.5	2.5	1.8	2.7	2.8	2.1	2.7	1.6	1.5	2.8	2.7	2.4	2.6
Noisy workplace	2.3	2.9	3.6	1.5	1.0	1.9	1.9	1.1	1.7	1.9	1.8	1.8	1.9	1.8	1.8	1.8	1.3	1.3	1.8	1.7	1.9	1.9
Miserableness	2.3	4.0	4.6	1.9	1.8	2.1	1.9	1.8	2.1	2.0	2.0	1.9	2.1	2.1	2.0	1.9	1.9	2.0	2.1	1.9	1.9	2.1
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	3.7	-1.9	-1.7	-1.6	-1.6	-1.3	-1.5	-1.9	-1.8	-1.6	-1.7	-1.4	-1.9	-1.4	-1.8	-1.8	-1.6	-1.4	-1.5	-1.9
Hand grip strength (left)	2.1	5.7	7.5	2.0	1.6	2.6	2.7	1.9	2.7	2.4	2.5	2.4	2.6	2.5	2.0	2.6	2.0	1.6	2.7	2.7	2.6	2.5
Age when periods started (menarche)	2.1	4.9	7.2	-1.9	-1.6	-2.7	-2.2	-2.2	-2.7	-2.4	-2.6	-1.7	-2.4	-2.6	-2.0	-2.1	-1.6	-1.5	-2.6	-2.2	-2.2	-2.3
Average weekly beer plus cider intake	2.1	3.1	4.2	1.3	1.0	2.0	2.0	1.9	1.9	1.8	1.6	1.7	1.9	2.0	1.4	1.9	1.3	1.2	2.0	2.0	2.0	1.8
Commuting to job workplace: Cycle	2.1	2.6	4.1	-1.2	-0.7	-2.0	-1.8	-0.9	-1.8	-1.5	-1.6	-1.5	-1.9	-2.0	-1.5	-1.9	-1.1	-1.1	-1.8	-1.9	-1.8	-1.7
Systolic blood pressure, automated reading	2.0	5.7	7.8	2.8	2.4	2.3	2.6	2.0	2.2	2.6	2.8	2.5	2.5	1.9	2.7	2.0	2.3	2.1	2.4	2.0	2.5	2.5
Pack years adult smoking proportion	2.0	3.0	4.3	1.6	1.1	2.1	1.9	1.5	1.8	2.0	2.1	1.5	1.9	1.9	1.9	1.7	1.1	1.2	1.9	1.7	1.8	1.9
Hand grip strength (right)	2.0	5.4	7.6	2.0	1.4	2.7	2.6	1.6	2.8	2.5	2.6	2.2	2.5	2.5	2.0	2.4	1.7	1.4	2.7	2.5	2.5	2.5
Neck or shoulder pain in last month	2.0	2.9	3.8	1.6	1.6	1.8	1.5	1.8	1.8	1.6	1.6	1.4	1.8	1.9	1.6	1.8	1.7	1.8	1.8	1.7	1.7	1.7
Mood swings	2.0	3.6	4.8	1.6	1.5	2.0	1.8	2.2	2.2	2.1	1.9	1.6	1.9	2.2	1.6	1.9	1.6	1.5	2.1	2.0	1.9	2.1
Illnesses of father: None of the above (group 1)	2.0	2.4	4.9	2.0	2.2	1.0	1.4	1.8	1.1	1.5	1.4	1.5	1.3	0.9	1.7	1.4	2.1	2.1	1.2	1.3	1.3	1.5
Age started oral contraceptive pill	2.0	2.4	4.0	-1.1	-1.0	-1.8	-1.6	-1.8	-2.0	-1.6	-1.6	-1.3	-1.6	-2.0	-1.1	-1.6	-1.2	-1.0	-1.9	-1.8	-1.6	-1.6
Depression (Nagel 2018)	1.9	2.8	3.2	1.6	1.6	1.7	1.7	1.7	1.8	1.7	1.8	1.7	1.7	1.7	1.6	1.6	1.6	1.5	1.7	1.6	1.7	1.8
Major Depression (MDD)	1.9	2.4	3.7	1.3	1.2	1.8	1.5	1.7	1.9	1.6	1.5	1.4	1.7	1.9	1.3	1.7	1.4	1.3	1.8	0.0	1.7	1.5
Schizophrenia (2014)	1.9	4.2	7.2	-2.3	-2.6	-1.7	-1.7	-2.5	-1.9	-1.8	-1.7	-2.2	-1.9	-1.9	-2.1	-2.1	-2.6	-2.7	-1.8	0.0	-2.0	-1.8
Systolic Blood Pressure	1.9	9.3	13.2	3.5	3.0	3.0	3.2	2.8	2.8	3.5	3.6	3.1	3.2	2.6	3.4	2.5	2.7	2.6	3.2	2.5	3.0	3.3
Trunk fat percentage	1.9	7.8	10.3	2.3	1.7	3.0	3.2	2.2	2.8	2.9	2.7	2.9	3.0	2.9	2.5	3.2	2.4	2.0	3.1	3.2	3.2	3.0
Mineral and other dietary supplements	1.9	2.5	3.7	1.8	1.7	1.3	1.7	1.1	1.3	1.5	1.4	1.9	1.5	1.2	1.8	1.7	1.9	1.8	1.4	1.6	1.6	1.6
Risk taking	1.9	2.8	3.9	1.5	1.5	1.7	1.6	1.5	2.0	1.7	1.8	1.5	1.7	1.9	1.5	1.8	1.5	1.5	1.8	1.8	1.7	1.7
Diabetes (father)	1.8	2.2	3.6	-1.6	-1.2	-1.7	-1.5	-1.0	-1.4	-1.7	-1.8	-1.3	-1.7	-1.6	-1.9	-1.4	-1.0	-1.3	-1.5	-1.3	-1.4	-1.6
Tinnitus: Yes, but not now, but have in the past	1.8	2.0	2.9	-1.4	-1.1	-1.4	-1.6	-1.1	-1.4	-1.4	-1.4	-1.7	-1.5	-1.3	-1.4	-1.5	-1.3	-1.1	-1.5	-1.5	-1.6	-1.4
Hayfever, allergic rhinitis or eczema	1.8	3.8	5.4	2.2	2.2	1.6	2.0	1.3	1.6	2.2	1.9	2.3	1.9	1.5	2.2	1.8	2.3	2.2	1.8	1.8	1.9	2.2
Had menopause	1.8	2.3	3.8	-1.7	-1.9	-1.3	-1.2	-1.5	-1.4	-1.4	-1.3	-1.7	-1.4	-1.4	-1.6	-1.4	-1.8	-2.0	-1.4	-1.4	-1.4	-1.5
Glaucoma (self-reported)	1.8	2.1	2.8	1.5	1.4	1.4	1.5	1.2	1.3	1.7	1.4	1.3	1.5	1.3	1.6	1.6	1.5	1.6	1.4	1.5	1.4	1.7
Fasting Glucose	1.7	2.0	4.1	-1.4	-1.7	-1.3	-1.0	-2.0	-1.6	-0.9	-1.2	-1.1	-1.3	-1.6	-1.3	-1.6	-1.6	-1.7	-1.3	-1.5	-1.2	-1.0
Blood White Count	1.7	12.6	19.4	-4.2	-4.4	-3.0	-3.3	-3.3	-3.3	-3.4	-3.5	-3.9	-3.3	-2.8	-3.7	-3.2	-4.3	-4.2	-3.2	-3.1	-3.4	-3.5
Medication: Co-codamol	1.7	2.0	2.8	1.1	0.9	1.6	1.4	1.4	1.6	1.6	1.4	1.0	1.6	1.7	1.2	1.6	1.1	1.1	1.6	1.6	1.5	1.6
Diabetes (mother)	1.7	2.2	3.7	1.9	1.9	1.2	1.5	1.7	1.3	1.7	1.8	1.5	1.3	1.0	1.7	1.0	1.6	1.4	1.4	1.0	1.3	1.5
Current tobacco smoking	1.7	2.7	4.4	1.1	0.6	2.1	1.8	1.4	1.9	1.9	1.8	1.0	1.9	2.1	1.4	1.9	0.9	0.9	2.0	2.0	1.7	1.9
Depression (self-reported)	1.7	2.0	2.9	-1.6	-1.6	-1.2	-1.4	-1.6	-1.1	-1.4	-1.3	-1.5	-1.3	-1.1	-1.6	-1.4	-1.6	-1.7	-1.2	-1.4	-1.4	-1.3
Ever taken oral contraceptive pill	1.7	1.9	5.9	1.7	2.1	0.7	0.8	1.3	0.6	1.5	1.0	1.1	1.1	0.8	1.8	1.1	1.9	2.4	0.9	1.1	0.9	1.4
Ever had hysterectomy (womb removed)	1.6	1.8	3.3	-1.7	-1.8	-1.2	-1.1	-1.6	-1.3	-1.2	-1.5	-1.3	-1.3	-1.2	-1.6	-0.9	-1.4	-1.6	-1.2	-0.9	-1.1	-1.2
Medication: Metformin	1.6	2.3	4.7	1.3	1.4	1.5	1.4	2.2	1.6	1.4	1.5	1.3	1.5	1.7	1.2	1.6	1.3	1.2	1.7	1.5	1.5	1.4
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	3.7	1.7	1.8	1.0	1.4	0.9	1.1	1.6	1.4	1.7	1.3	0.8	1.6	1.2	1.9	1.8	1.2	1.1	1.3	1.7
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	4.9	1.3	1.6	1.4	1.5	2.2	1.6	1.6	1.3	1.6	1.5	1.7	1.2	1.7	1.8	1.6	1.6	1.8	1.6	1.6
Body fat percentage	1.6	6.2	8.7	2.1	1.5	2.7	2.9	1.9	2.5	2.7	2.5	2.6	2.7	2.6	2.3	2.8	2.0	1.7	2.8	2.8	2.9	2.7
Leg fat percentage (right)	1.6	5.9	8.9	2.0	1.3	2.8	3.0	1.8	2.5	2.7	2.5	2.5	2.7	2.5	2.2	2.7	1.8	1.5	2.7	2.6	2.8	2.7
Comparative height size at age 10	1.6	8.6	10.7	2.7	2.6	2.9	3.0	2.4	3.0	2.9	2.8	3.0	3.0	2.9	2.7	3.3	3.1	2.8	3.0	3.2	3.1	3.0
Medication: Ibuprofen	1.5	1.8	3.0	1.0	1.0	1.4	1.4	1.3	1.5	1.3	1.2	1.2	1.4	1.5	0.9	1.7	1.4	1.1	1.5	1.7	1.4	1.4
Illnesses of siblings: Diabetes	1.5	1.9	5.6	1.7	2.4	0.6	0.9	1.9	1.0	1.1	1.0	1.5	0.9	0.8	1.3	1.0	2.1	2.0	0.9	1.1	1.0	1.0
Leg fat percentage (left)	1.5	5.5	8.2	1.8	1.1	2.7	2.9	1.7	2.4	2.6	2.4	2.3	2.6	2.5	2.1	2.6	1.7	1.3	2.7	2.6	2.7	2.7
Neuroticism (Nagel 2018)	1.4	3.4	4.0	1.8	1.9	1.8	1.8	1.9	2.0	2.0	2.0	1.7	1.8	1.7	1.7	1.7	1.8	1.7	1.9	1.8	1.8	2.0
Schizophrenia (2018)	1.4	2.8	4.8	-1.9	-2.1	-1.7	-1.4	-2.2	-1.8	-1.3	-1.7	-1.8	-1.6	-1.7	-1.7	-1.5	-1.9	-2.0	-1.6	0.0	-1.6	-1.4
Type 2 Diabetes (T2D) (2012)	1.4	1.6	2.6	1.0	0.8	1.5	1.4	1.2	1.6	1.2	1.4	1.2	1.4	1.5	1.0	1.4	1.0	0.8	1.6	0.0	1.4	1.3
Type 2 Diabetes (T2D) (2018)	1.4	2.6	3.3	1.4	1.3	1.7	1.7	1.8	1.7	1.6	1.6	1.6	1.6	1.8	1.4	1.6	1.3	1.2	1.8	1.7	1.7	1.6
Past tobacco smoking	1.4	2.6	3.7	-1.4	-1.1	-1.7	-1.8	-0.9	-1.6	-1.9	-1.6	-1.4	-1.8	-1.6	-1.5	-1.8	-1.5	-1.2	-1.9	-1.8	-1.7	-1.9
Lung cancer (father)	1.4	1.6	2.2	1.4	1.4	1.2	0.9	1.5	1.4	1.2	1.4	0.8	1.2	1.4	1.4	1.2	1.1	1.3	1.3	1.2	1.0	1.2
Tinnitus: Yes, now most or all of the time	1.4	1.7	2.3	1.3	1.2	1.4	1.2	1.5	1.3	0.9	1.2	1.3	1.3	1.4	1.3	1.5	1.2	1.4	1.2	1.4	1.3	1.0
Supplements: Fish oil (including cod liver oil)	1.4	1.8	2.3	-1.3	-1.0	-1.5	-1.5	-0.9	-1.5	-1.2	-1.5	-1.5	-1.4	-1.4	-1.4	-1.4	-1.0	-1.0	-1.4	-1.3	-1.5	-1.4
Hearing difficulty/problems: Yes	1.3	2.0	2.8	-1.6	-1.6	-1.3	-1.5	-1.6	-1.7	-1.2	-1.6	-1.6	-1.3	-1.3	-1.3	-1.2	-1.5	-1.4	-1.3	-1.4	-1.4	-1.2
Impedance of leg (right)	1.3	6.2	8.8	2.5	2.3	2.8	2.3	2.7	3.0	2.4	3.0	2.0	2.6	2.8	2.5	2.2	1.9	2.1	2.7	2.2	2.3	2.4
Allergy	1.3	3.1	4.3	-1.9	-1.8	-1.6	-1.7	-1.0	-1.5	-2.1	-1.9	-1.8	-1.8	-1.5	-2.1	-1.5	-1.8	-1.8	-1.7	-1.6	-1.7	-2.0
Alcohol intake versus 10 years previously	1.3	2.0	5.1	0.9	0.8	1.8	1.1	2.3	1.8	0.8	1.3	1.1	1.5	2.2	0.9	1.6	0.7	1.0	1.6	1.5	1.4	1.0
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.1	-1.5	-1.6	-1.3	-1.4	-0.7	-1.4	-1.3	-1.3	-1.6	-1.5	-1.3	-1.5	-1.6	-1.8	-1.7	-1.4	-1.5	-1.4	-1.5
Medication: Aspirin	1.3	1.7	3.4	0.8	0.7	1.6	1.3	1.6	1.6	1.2	1.2	1.2	1.4	1.8	0.9	1.5	0.9	0.8	1.5	1.5	1.4	1.3
Schizophrenia vs Biploar Disorder	1.2	1.5	3.3	1.7	1.8	0.8	1.1	1.0	0.8	1.4	1.2	1.2	1.1	0.7	1.6	1.0	1.7	1.7	1.0	0.0	1.0	1.4
Alzheimer’s Disease (in father)	1.2	1.3	1.9	-1.4	-1.4	-0.9	-1.0	-0.9	-1.0	-1.4	-1.3	-0.9	-1.1	-0.9	-1.3	-0.9	-1.4	-1.3	-1.1	-1.0	-0.9	-1.3
Age at First Birth	1.2	1.7	2.8	-0.7	-0.4	-1.6	-1.6	-1.7	-1.5	-1.4	-1.4	-1.2	-1.4	-1.7	-0.8	-1.2	-0.4	-0.3	-1.6	-1.4	-1.5	-1.2
Mean Putamen Volume	1.2	1.3	3.0	-1.3	-1.5	-0.6	-1.2	-1.2	-0.6	-1.2	-0.7	-1.4	-1.0	-0.4	-1.2	-1.1	-1.7	-1.5	-0.9	-1.1	-1.1	-1.2
Lupus	1.2	1.8	3.0	1.4	1.6	1.3	1.3	1.7	1.4	1.3	1.3	1.6	1.3	1.3	1.4	1.2	1.5	1.5	1.3	0.0	1.4	1.2
Primary Biliary Cirrhosis	1.2	1.7	3.1	1.0	1.0	1.5	1.2	1.6	1.7	1.1	1.2	1.2	1.4	1.8	0.9	1.6	1.2	1.1	1.5	0.0	1.4	1.2
Blood Eosinophil Count	1.2	9.6	15.7	2.5	1.4	3.6	4.0	2.2	3.1	3.8	3.3	3.2	3.5	3.1	3.0	3.0	1.9	1.7	3.5	3.3	3.5	3.6
Cardiovascular Disease	1.2	3.8	4.9	2.0	1.5	2.2	2.2	1.3	2.0	2.1	2.2	2.1	2.1	1.9	2.1	1.8	1.6	1.5	2.1	1.8	2.1	2.1
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.5	-1.3	-1.4	-1.1	-1.0	-1.6	-1.3	-1.2	-1.4	-1.2	-1.1	-1.1	-1.3	-0.8	-1.0	-1.2	-1.1	-0.9	-1.0	-1.0
Supplements: Glucosamine	1.2	1.6	2.5	-1.5	-1.6	-1.0	-1.3	-0.9	-1.1	-1.2	-1.2	-1.5	-1.2	-1.0	-1.4	-1.3	-1.6	-1.5	-1.1	-1.2	-1.2	-1.2
Trunk fat mass	1.2	5.3	8.1	1.9	1.3	2.5	2.8	1.5	2.3	2.5	2.3	2.5	2.5	2.3	2.1	2.7	1.9	1.5	2.6	2.6	2.7	2.6
Mouth/teeth dental problems	1.2	1.8	2.6	-1.0	-0.8	-1.5	-1.5	-1.2	-1.4	-1.5	-1.4	-1.2	-1.5	-1.5	-1.2	-1.6	-1.0	-1.0	-1.5	-1.6	-1.5	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	2.2	0.8	0.5	1.4	1.4	0.7	1.5	1.4	1.2	1.0	1.4	1.4	0.9	1.5	1.0	0.7	1.4	1.5	1.4	1.5
Ovarian Cancer	1.1	1.5	3.8	1.7	1.9	0.7	1.0	1.0	0.8	1.0	1.0	1.4	0.9	0.7	1.5	1.0	1.8	1.9	0.7	0.9	1.0	0.9
Ulcerative Colitis	1.1	1.6	3.4	0.8	0.8	1.5	1.2	1.5	1.6	1.1	1.1	1.1	1.4	1.9	0.8	1.7	1.1	1.0	1.6	0.0	1.4	1.3
Chronic bronchitis/emphysema (father)	1.1	1.3	2.9	1.3	1.6	0.8	0.8	0.8	0.9	1.1	0.9	1.3	1.0	1.0	1.2	1.0	1.6	1.7	0.9	1.1	1.0	1.1
Impedance of leg (left)	1.1	5.3	8.1	2.3	2.1	2.7	2.0	2.5	2.8	2.2	2.8	1.7	2.4	2.8	2.3	2.1	1.7	2.0	2.5	2.1	2.0	2.2
Leg fat mass (right)	1.1	4.3	7.0	1.7	1.0	2.3	2.6	1.3	2.0	2.4	2.1	2.2	2.3	2.0	1.9	2.3	1.6	1.2	2.3	2.3	2.5	2.4
Pack years of smoking	1.1	1.6	2.4	1.1	0.7	1.5	1.4	0.9	1.3	1.4	1.5	1.1	1.4	1.4	1.4	1.2	0.7	0.8	1.4	1.2	1.3	1.4
Leg fat mass (left)	1.1	4.2	6.8	1.6	0.9	2.3	2.6	1.2	2.0	2.3	2.1	2.1	2.3	2.0	1.8	2.3	1.5	1.1	2.3	2.3	2.4	2.4
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.0	1.1	1.2	1.3	1.0	1.4	1.4	1.2	1.3	1.0	1.2	1.4	1.1	1.1	1.0	1.1	1.3	1.1	1.1	1.2
Arm fat percentage (right)	1.0	3.8	5.5	1.4	1.0	2.1	2.4	1.4	1.9	2.1	1.7	2.0	2.1	2.1	1.6	2.3	1.6	1.3	2.2	2.4	2.3	2.2
Pulse rate	1.0	1.7	2.6	-1.2	-1.4	-1.2	-1.1	-1.6	-1.4	-1.2	-1.2	-1.2	-1.2	-1.4	-1.2	-1.4	-1.4	-1.5	-1.3	-1.4	-1.2	-1.2
Asthma	1.0	2.0	2.8	1.4	1.1	1.6	1.4	1.2	1.4	1.5	1.7	1.4	1.6	1.6	1.6	1.3	1.0	1.2	1.5	1.4	1.4	1.5
Medication: Amlodipine	1.0	1.3	2.2	0.8	0.3	1.4	1.4	0.6	1.3	1.3	1.2	1.0	1.4	1.4	0.9	1.4	0.7	0.4	1.5	1.4	1.4	1.4
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.1	1.3	1.2	1.0	1.0	0.4	1.1	1.4	1.2	0.9	1.1	0.9	1.1	0.9	1.3	1.1	1.1	0.8	1.0	1.4
Shortness of breath walking on level ground	1.0	1.2	2.7	0.4	-0.1	1.6	1.2	0.6	1.5	1.1	1.2	0.8	1.3	1.6	0.8	1.3	0.1	0.2	1.4	1.3	1.3	1.1
Whole body fat mass	1.0	4.2	6.6	1.6	1.0	2.2	2.6	1.3	2.0	2.3	2.0	2.2	2.3	2.0	1.8	2.4	1.6	1.2	2.3	2.4	2.4	2.3
Loneliness, isolation	1.0	1.3	2.3	0.8	0.6	1.2	1.4	1.2	1.2	1.5	1.2	1.1	1.2	1.2	0.9	1.1	0.9	0.6	1.3	1.3	1.3	1.4
Mother’s age at death	1.0	1.2	1.9	-1.2	-1.2	-0.9	-1.0	-0.7	-1.1	-1.4	-1.2	-1.0	-1.1	-1.0	-1.2	-0.9	-1.2	-1.2	-1.1	-1.0	-1.0	-1.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.7	1.0	0.6	1.2	1.5	0.4	1.0	1.6	1.2	1.2	1.3	0.9	1.1	1.1	0.9	0.6	1.2	1.1	1.3	1.5
Pain experienced in last month	1.0	1.6	2.4	-1.0	-0.9	-1.4	-1.3	-1.6	-1.5	-1.4	-1.3	-1.2	-1.3	-1.5	-0.9	-1.4	-0.9	-0.7	-1.5	-1.3	-1.4	-1.4
Respiratory disease	0.9	2.0	2.8	1.4	1.3	1.4	1.3	1.7	1.4	1.3	1.4	1.4	1.5	1.5	1.5	1.4	1.2	1.3	1.4	1.4	1.4	1.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.8	1.0	0.5	1.2	1.2	0.0	1.2	1.3	1.3	0.8	1.2	1.0	1.1	0.9	0.8	0.5	1.2	0.9	1.0	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	1.8	1.1	1.1	1.1	1.2	1.1	1.2	1.3	1.1	1.3	1.2	1.2	1.1	1.2	1.2	1.1	1.2	1.2	1.3	1.3
Father’s age at death	0.9	1.2	1.7	-0.9	-0.6	-1.3	-1.2	-1.1	-1.2	-1.2	-1.2	-1.0	-1.2	-1.3	-1.0	-1.0	-0.6	-0.6	-1.2	-1.0	-1.1	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.7	-1.4	-1.6	-0.6	-0.8	-1.4	-0.5	-0.9	-0.8	-1.1	-0.8	-0.5	-1.2	-0.7	-1.5	-1.5	-0.7	-0.7	-0.8	-0.8
Breast cancer (self-reported)	0.9	1.1	1.9	-1.2	-1.3	-0.7	-1.0	-0.9	-0.8	-1.1	-0.8	-1.2	-1.0	-0.8	-1.1	-1.0	-1.4	-1.4	-0.9	-1.1	-1.0	-1.1
Diastolic blood pressure, automated reading	0.9	2.7	4.6	-1.8	-2.0	-1.4	-1.4	-1.6	-1.5	-1.6	-1.5	-1.6	-1.6	-1.6	-1.8	-1.7	-1.9	-2.1	-1.4	-1.6	-1.5	-1.6
Supplements: Calcium	0.9	1.0	2.2	-1.2	-1.1	-0.5	-1.3	-0.3	-0.3	-1.0	-0.6	-1.5	-0.9	-0.2	-1.2	-1.0	-1.4	-1.2	-0.6	-1.1	-1.1	-1.0
Blood Platelet Count	0.8	9.6	19.8	-3.3	-3.7	-2.8	-2.6	-4.5	-2.9	-2.9	-3.0	-2.8	-2.9	-3.0	-3.0	-2.7	-3.4	-3.6	-3.0	-2.9	-2.7	-2.8
Hypothyroidism (self reported)	0.8	1.7	3.2	1.2	1.5	1.1	1.1	1.8	1.3	1.4	1.1	1.2	1.2	1.3	1.1	1.3	1.6	1.6	1.2	1.4	1.2	1.4
Relative age of first facial hair	0.8	1.6	2.9	-1.2	-1.3	-1.2	-1.3	-1.7	-1.4	-1.0	-1.2	-1.5	-1.2	-1.3	-1.0	-1.3	-1.3	-1.1	-1.3	-1.3	-1.4	-1.0
Ever used hormone-replacement therapy (HRT)	0.8	1.1	2.2	-1.1	-1.4	-0.7	-0.8	-1.1	-0.9	-0.8	-0.7	-1.3	-0.9	-0.9	-1.0	-1.0	-1.4	-1.5	-0.8	-1.0	-1.0	-0.8
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.4	1.1	0.8	1.0	1.0	0.6	0.8	1.2	1.1	0.7	1.1	0.8	1.2	0.8	0.8	0.8	1.0	0.8	0.9	1.1
Fluid intelligence score	0.8	1.7	4.0	-0.5	-0.4	-1.6	-1.1	-1.7	-1.7	-1.4	-1.2	-0.8	-1.4	-2.0	-0.6	-1.5	-0.6	-0.5	-1.6	-1.6	-1.3	-1.3
Alcohol intake frequency.	0.8	1.8	3.2	-1.3	-1.6	-1.0	-1.3	-1.4	-1.2	-1.5	-1.1	-1.5	-1.2	-1.0	-1.1	-1.3	-1.8	-1.5	-1.3	-1.4	-1.3	-1.5
Arm fat percentage (left)	0.8	3.4	5.3	1.3	0.8	2.0	2.3	1.2	1.8	2.1	1.6	2.0	2.0	1.9	1.6	2.2	1.5	1.1	2.0	2.2	2.2	2.1
Smoking status: Current	0.8	1.3	2.7	0.4	-0.1	1.6	1.3	0.7	1.4	1.4	1.3	0.4	1.4	1.6	0.9	1.3	0.2	0.2	1.5	1.4	1.1	1.4
Eye problems/disorders: Glaucoma	0.8	0.9	1.8	0.9	0.6	0.9	1.1	0.4	0.8	1.3	0.9	0.8	1.0	0.7	1.0	1.0	1.0	0.8	1.0	1.0	1.0	1.3
Breast Cancer	0.7	1.6	2.1	1.4	1.3	1.2	1.0	1.1	1.2	1.5	1.4	1.0	1.3	1.3	1.4	1.2	1.3	1.4	1.3	1.0	1.1	1.4
Chronotype (morning person)	0.7	1.7	2.9	1.3	0.9	1.4	1.5	0.5	1.3	1.7	1.6	1.2	1.4	1.1	1.4	1.2	1.1	0.8	1.4	1.1	1.3	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	1.5	0.9	0.8	1.1	1.1	0.9	1.2	1.1	1.2	1.0	1.0	1.0	0.8	0.9	0.8	0.6	1.1	0.9	1.0	1.1
Hearing difficulty/problems with background noise	0.7	1.1	1.6	0.9	0.9	1.1	0.9	1.1	1.0	1.1	0.9	0.9	1.1	1.2	1.1	1.3	1.0	1.1	1.1	1.2	1.1	1.1
Hair/balding pattern: Pattern 2	0.7	0.9	1.5	1.2	1.2	0.8	0.9	1.2	0.7	0.9	1.0	1.0	0.9	0.7	1.2	0.8	1.0	1.1	0.8	0.8	0.8	0.8
Heart attack	0.7	0.9	1.9	0.5	0.3	1.1	1.0	1.2	1.1	0.8	0.7	0.9	1.0	1.4	0.7	1.2	0.5	0.6	1.1	1.2	1.1	0.9
Neuroticism score	0.7	1.4	2.0	0.9	0.9	1.2	1.1	1.4	1.4	1.4	1.2	1.1	1.2	1.4	0.9	1.1	1.0	0.9	1.4	1.2	1.2	1.4
Arm fat mass (right)	0.7	2.9	5.0	1.3	0.7	1.8	2.2	0.9	1.6	1.9	1.5	1.9	1.9	1.6	1.4	2.1	1.5	1.0	1.9	2.1	2.1	2.0
Emphysema/chronic bronchitis	0.7	0.8	1.6	0.9	0.3	1.2	1.1	-0.1	0.9	1.1	1.3	0.7	1.1	0.8	1.1	0.6	0.3	0.3	1.0	0.6	0.8	1.0
Medication: Aspirin	0.7	0.9	2.3	0.3	0.2	1.2	0.8	1.3	1.3	0.7	0.7	0.7	0.9	1.5	0.4	1.2	0.4	0.4	1.1	1.2	1.0	0.8
Smoking status: Previous	0.7	1.0	1.8	1.0	1.1	0.9	1.0	0.8	0.9	1.0	0.8	1.0	1.0	0.9	0.9	1.2	1.4	1.2	1.1	1.1	1.0	1.1
Ever smoked	0.7	1.3	2.2	0.9	0.6	1.3	1.3	0.5	1.2	1.5	1.2	0.9	1.4	1.2	1.0	1.2	0.9	0.6	1.5	1.3	1.2	1.4
Impedance of whole body	0.7	3.5	6.3	1.7	1.6	2.2	1.5	2.3	2.4	1.6	2.1	1.3	2.0	2.5	1.7	1.8	1.4	1.7	2.1	1.8	1.6	1.7
Number of treatments/medications taken	0.6	1.0	2.1	0.6	0.7	1.1	0.8	1.4	1.2	0.9	0.8	0.8	1.0	1.4	0.7	1.2	0.9	0.8	1.2	1.2	1.0	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.3	0.9	0.6	1.5	1.3	0.6	1.5	1.3	1.5	1.0	1.3	1.4	1.0	1.2	0.7	0.5	1.4	1.1	1.2	1.4
Qualifications: CSEs or equivalent	0.6	0.8	1.3	0.8	0.9	0.8	0.9	1.1	0.9	0.7	0.7	0.9	0.8	0.9	0.7	1.0	1.0	1.0	0.8	1.0	0.9	0.7
Diabetes (self-reported)	0.6	0.9	1.7	0.8	0.8	0.9	1.1	1.3	0.9	0.8	0.8	1.2	0.9	1.0	0.7	1.1	0.9	0.7	1.0	1.1	1.1	0.8
Length of working week for main job	0.6	0.6	2.2	-1.0	-1.5	-0.4	-0.4	-1.2	-0.7	-0.5	-0.7	-0.7	-0.5	-0.5	-0.7	-0.5	-1.2	-1.1	-0.6	-0.5	-0.5	-0.5
Pulse wave reflection index	0.6	0.8	1.7	0.7	0.7	1.0	0.9	1.3	1.0	0.8	1.0	0.5	0.9	1.1	0.7	1.1	0.7	0.7	1.0	1.1	0.8	0.9
Comparative body size at age 10	0.6	1.7	2.3	1.2	1.0	1.4	1.4	1.2	1.3	1.2	1.3	1.4	1.4	1.4	1.2	1.4	1.2	1.0	1.4	1.3	1.5	1.2
Number of full sisters	0.6	0.7	1.5	0.4	0.3	1.0	0.8	1.0	0.8	0.8	0.7	0.5	0.9	1.1	0.7	1.2	0.5	0.6	0.9	1.1	0.9	0.8
Friendships satisfaction	0.6	0.7	1.5	-1.2	-1.0	-0.8	-0.9	-0.4	-0.7	-0.9	-1.1	-1.0	-0.9	-0.5	-1.1	-0.6	-0.9	-0.8	-0.8	-0.5	-0.8	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	0.4	0.3	1.2	0.7	1.3	1.2	0.9	1.0	0.3	0.9	1.4	0.5	0.8	0.2	0.3	1.1	0.9	0.7	0.8
Arm fat mass (left)	0.6	2.7	5.0	1.2	0.6	1.7	2.2	0.7	1.5	1.9	1.5	1.9	1.8	1.4	1.4	1.9	1.3	0.9	1.8	1.9	2.0	1.9
Commuting to job workplace: Public transport	0.6	0.7	2.0	-0.8	-1.2	-0.5	-0.5	-1.4	-0.7	-0.7	-0.5	-0.8	-0.6	-0.9	-0.6	-0.9	-1.2	-1.2	-0.7	-1.0	-0.7	-0.7
Fractured/broken bones in last 5 years	0.6	0.7	1.7	-0.7	-1.0	-0.7	-0.7	-1.3	-1.0	-0.8	-0.7	-0.7	-0.7	-0.9	-0.5	-0.9	-1.0	-0.9	-0.8	-1.0	-0.8	-0.8
Alzheimer’s Disease (in mother)	0.5	0.6	1.0	-0.5	-0.3	-1.0	-0.9	-0.5	-0.9	-0.9	-0.8	-0.7	-0.9	-1.0	-0.7	-0.8	-0.5	-0.4	-0.9	-0.9	-0.8	-1.0
Body Mass Index (BMI) (2010)	0.5	0.6	1.3	-1.1	-1.1	-0.5	-0.8	-0.6	-0.5	-1.0	-0.9	-0.9	-0.7	-0.3	-1.0	-0.5	-1.0	-0.9	-0.6	0.0	-0.7	-0.8
Relative age voice broke	0.5	0.7	1.8	-0.7	-0.8	-0.8	-0.8	-1.4	-1.0	-0.8	-0.9	-0.7	-0.8	-0.9	-0.5	-0.7	-0.6	-0.5	-1.0	-0.7	-0.8	-0.7
Medication: Atenolol	0.5	0.6	1.0	0.8	0.6	0.8	0.9	0.7	0.6	0.6	0.7	0.9	0.9	0.8	0.9	1.0	0.8	0.8	0.8	0.9	0.9	0.7
High blood pressure (mother)	0.5	0.6	1.3	-0.5	0.1	-1.0	-1.1	-0.1	-0.9	-1.0	-0.9	-0.7	-1.0	-0.8	-0.7	-0.9	-0.2	-0.0	-1.0	-0.8	-1.0	-1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.6	0.2	0.4	0.8	0.6	1.9	0.9	0.6	0.5	0.4	0.7	1.1	0.2	0.9	0.3	0.3	0.9	1.0	0.7	0.6
Hip circumference	0.5	2.1	3.8	1.3	0.9	1.3	1.9	0.3	1.0	1.7	1.2	1.9	1.5	0.9	1.4	1.7	1.6	1.2	1.4	1.6	1.8	1.8
Qualifications: A levels/AS levels or equivalent	0.5	1.2	2.4	-0.2	0.5	-1.5	-1.3	-0.4	-1.4	-1.1	-1.1	-0.7	-1.3	-1.5	-0.5	-1.4	0.0	0.3	-1.4	-1.3	-1.3	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.0	0.5	0.2	1.0	0.8	0.9	1.0	0.8	0.8	0.5	0.9	1.0	0.5	0.8	0.4	0.3	1.0	0.8	0.8	0.8
Illnesses of mother	0.5	0.6	1.4	0.2	-0.3	1.2	0.9	0.2	1.1	0.6	0.8	0.4	0.9	1.1	0.5	1.0	-0.0	-0.0	1.0	1.0	0.9	0.7
Breastfed as a baby	0.5	0.6	1.1	-0.8	-0.6	-0.9	-0.9	-0.3	-1.0	-0.7	-1.1	-0.9	-0.9	-0.9	-0.8	-0.8	-0.5	-0.4	-0.9	-0.8	-0.9	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.8	1.3	1.3	0.5	1.0	0.5	0.5	1.0	1.0	1.2	0.8	0.3	1.2	0.6	1.1	0.9	0.7	0.5	0.9	0.9
Migraine (self-reported)	0.5	0.6	1.0	-1.0	-0.6	-0.6	-0.9	0.6	-0.5	-0.8	-0.8	-1.0	-0.8	-0.2	-1.0	-0.6	-1.0	-0.7	-0.6	-0.6	-0.8	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	0.6	0.5	1.0	1.0	0.5	1.0	0.8	0.9	0.8	0.9	0.9	0.7	0.9	0.5	0.4	1.0	0.8	0.9	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	1.4	-0.5	-0.4	-1.0	-0.8	-0.9	-1.0	-0.6	-0.7	-0.6	-0.9	-1.2	-0.6	-1.1	-0.5	-0.5	-1.0	-1.0	-0.9	-0.7
Asthma (self-reported)	0.5	1.0	1.5	1.0	0.8	1.1	1.0	0.6	1.0	1.1	1.2	1.0	1.1	1.1	1.2	0.9	0.7	0.8	1.1	1.0	1.0	1.0
Ever depressed for a whole week	0.5	0.6	1.1	0.6	0.8	0.6	0.7	0.9	0.6	0.9	0.5	0.6	0.8	0.8	0.7	1.0	0.9	0.9	0.8	1.0	0.8	1.0
Alcohol drinker status: Previous	0.5	0.5	0.9	-0.3	-0.2	-0.8	-0.8	-0.9	-0.9	-0.9	-0.6	-0.7	-0.7	-0.9	-0.3	-0.9	-0.4	-0.3	-0.9	-0.9	-0.9	-0.9
Lung FVC	0.4	1.8	2.9	1.4	1.5	1.3	1.1	1.0	1.4	1.3	1.3	1.1	1.3	1.3	1.3	1.4	1.7	1.6	1.3	1.4	1.2	1.4
Neuroticism	0.4	0.9	1.2	0.9	1.0	0.9	0.9	0.9	1.1	1.0	1.0	0.9	1.0	1.0	0.9	1.0	1.1	1.0	1.0	1.0	0.9	1.0
Stomach or abdominal pain in last month	0.4	0.5	1.1	0.9	1.0	0.5	0.5	1.0	0.4	0.8	0.8	0.6	0.6	0.5	1.0	0.4	0.7	0.9	0.6	0.4	0.5	0.6
Body mass index (BMI)	0.4	1.7	3.4	0.9	0.4	1.4	1.8	0.6	1.1	1.5	1.1	1.6	1.4	1.1	1.1	1.5	1.0	0.6	1.4	1.5	1.7	1.6
Impedance of arm (right)	0.4	1.9	4.4	1.1	1.3	1.6	0.8	2.0	1.8	1.0	1.2	0.9	1.4	2.1	1.1	1.5	1.2	1.5	1.5	1.5	1.1	1.0
Medication: Lansoprazole	0.4	0.5	1.0	-0.9	-0.9	-0.5	-0.7	-0.7	-0.4	-0.7	-0.7	-0.7	-0.6	-0.4	-0.9	-0.5	-0.9	-1.0	-0.5	-0.6	-0.6	-0.6
Birth weight of first child	0.4	0.7	2.2	-0.7	-0.9	-0.7	-0.8	-1.5	-0.7	-1.0	-0.8	-0.6	-0.8	-0.8	-0.6	-0.8	-0.8	-0.6	-0.9	-0.7	-0.7	-0.9
Medication: Paracetamol	0.4	0.6	2.4	1.1	1.6	-0.1	0.3	1.1	-0.1	0.5	0.2	1.1	0.3	-0.0	0.9	0.3	1.4	1.5	0.0	0.3	0.5	0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.1	-0.9	-1.0	-0.7	-0.7	-0.9	-0.8	-0.6	-0.7	-0.9	-0.8	-0.8	-0.8	-0.8	-1.0	-1.0	-0.8	-0.8	-0.8	-0.7
Worry too long after embarrassment	0.4	0.7	1.3	-0.5	-0.2	-1.0	-0.9	-0.5	-0.9	-0.7	-0.7	-0.8	-0.9	-1.1	-0.7	-1.1	-0.5	-0.5	-0.9	-1.0	-1.0	-0.8
Number of children fathered	0.4	0.5	1.4	-0.6	-0.8	-0.6	-0.5	-1.2	-0.6	-0.2	-0.3	-0.9	-0.6	-0.8	-0.6	-0.7	-0.8	-1.0	-0.6	-0.7	-0.6	-0.3
Angina (self-reported)	0.4	0.5	1.1	0.5	0.1	1.1	0.9	0.7	0.8	0.8	0.9	0.6	0.9	1.0	0.7	0.7	0.1	0.2	0.9	0.7	0.8	0.8
Medication: Allopurinol	0.4	0.6	0.9	-0.7	-0.4	-0.9	-0.9	-0.7	-0.8	-0.8	-0.9	-0.6	-0.9	-0.9	-0.9	-0.8	-0.4	-0.5	-0.8	-0.8	-0.8	-0.8
Knee pain experienced in last month	0.4	0.6	1.0	0.7	0.5	0.9	0.9	0.4	0.8	0.9	0.8	1.0	0.9	0.8	0.8	0.8	0.6	0.6	0.8	0.8	1.0	0.8
Medication: Blood pressure	0.4	0.7	2.9	-1.2	-1.7	-0.0	-0.6	-0.9	-0.3	-0.6	-0.4	-1.1	-0.4	0.0	-0.8	-0.6	-1.6	-1.5	-0.3	-0.5	-0.6	-0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.0	0.1	0.6	-1.0	-1.0	-0.4	-0.9	-0.7	-0.6	-0.5	-0.7	-0.9	-0.1	-0.8	0.2	0.5	-0.9	-0.8	-0.9	-0.7
Myopia	0.4	0.5	1.2	-0.3	0.5	-1.1	-1.0	0.1	-0.9	-0.8	-1.0	-0.4	-0.9	-0.8	-0.4	-0.7	0.2	0.5	-1.0	-0.6	-0.8	-0.8
Allergy or Eczema	0.3	0.7	1.2	0.8	0.7	0.7	0.9	0.3	0.6	1.1	0.7	0.9	0.9	0.6	0.9	0.8	0.9	0.8	0.8	0.8	0.9	1.1
Angina	0.3	0.3	0.8	0.3	-0.1	0.9	0.7	0.5	0.6	0.6	0.7	0.4	0.7	0.8	0.5	0.6	-0.1	0.0	0.7	0.6	0.7	0.6
Vitamin and mineral supplements	0.3	0.5	1.2	0.7	0.5	0.5	1.0	0.4	0.1	0.6	0.3	1.1	0.6	0.2	0.8	0.8	0.8	0.7	0.5	0.7	0.9	0.7
Supplements: Zinc	0.3	0.3	0.7	-0.5	-0.4	-0.2	-0.8	0.0	-0.0	-0.8	-0.4	-0.8	-0.5	0.1	-0.6	-0.5	-0.6	-0.5	-0.3	-0.5	-0.7	-0.7
Severe depression (siblings)	0.3	0.3	0.8	-0.0	0.0	-0.6	-0.7	-0.6	-0.5	-0.6	-0.2	-0.5	-0.6	-0.7	-0.1	-0.9	-0.4	-0.2	-0.6	-0.9	-0.7	-0.7
Multivitamins +/- minerals	0.3	0.4	0.8	-0.6	-0.4	-0.6	-0.9	-0.6	-0.3	-0.7	-0.6	-0.8	-0.7	-0.4	-0.7	-0.7	-0.5	-0.5	-0.6	-0.7	-0.8	-0.7
Medication: Ramipril	0.3	0.4	0.7	0.9	0.8	0.4	0.5	0.1	0.5	0.8	0.7	0.7	0.6	0.3	0.8	0.4	0.7	0.8	0.5	0.3	0.6	0.7
Weight	0.3	1.3	3.0	0.9	0.3	1.1	1.7	0.1	0.9	1.3	1.0	1.5	1.2	0.8	1.0	1.3	0.9	0.5	1.2	1.3	1.5	1.4
Headache pain in last month	0.3	0.5	2.0	0.8	1.1	0.5	0.5	1.4	0.9	0.4	0.6	0.9	0.5	0.7	0.5	0.5	0.9	0.9	0.6	0.6	0.6	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	-0.6	-1.0	-0.3	-0.4	-1.0	-0.4	-0.3	-0.2	-0.7	-0.4	-0.5	-0.5	-0.7	-1.0	-1.0	-0.4	-0.8	-0.5	-0.3
Age at first live birth	0.3	0.5	1.0	-0.1	0.2	-1.0	-0.9	-0.5	-0.9	-0.8	-0.6	-0.3	-0.8	-1.0	-0.2	-1.0	-0.2	0.0	-1.0	-1.0	-0.8	-0.8
Health satisfaction	0.3	0.4	0.6	0.7	0.6	0.8	0.5	0.5	0.7	0.4	0.7	0.6	0.7	0.8	0.8	0.6	0.5	0.7	0.6	0.6	0.6	0.4
Medication: Omeprazole	0.3	0.4	0.8	0.6	0.3	0.8	0.6	0.1	0.6	0.9	0.8	0.6	0.7	0.7	0.9	0.5	0.3	0.5	0.6	0.5	0.7	0.8
Hypertension (Self-reported)	0.3	0.9	1.3	0.9	0.5	1.1	1.1	0.2	0.9	1.1	1.1	1.0	1.1	0.9	1.1	0.9	0.7	0.6	1.1	0.9	1.1	1.1
Illnesses of father: Heart disease	0.3	0.4	0.8	0.2	-0.1	0.9	0.9	0.6	0.9	0.6	0.7	0.7	0.7	0.8	0.3	0.8	0.3	-0.0	0.8	0.9	0.8	0.7
Medication for cholesterol	0.3	0.4	0.8	-0.5	-0.4	-0.8	-0.5	-0.7	-0.8	-0.9	-0.8	-0.4	-0.7	-0.9	-0.6	-0.5	-0.3	-0.4	-0.8	-0.6	-0.6	-0.8
Number of self-reported non-cancer illnesses	0.3	0.5	0.8	0.8	0.7	0.6	0.6	0.5	0.4	0.8	0.7	0.8	0.7	0.6	0.9	0.6	0.6	0.7	0.6	0.5	0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.8	0.3	-0.2	0.8	0.8	-0.5	0.5	0.9	0.6	0.7	0.7	0.5	0.7	0.6	0.2	0.2	0.6	0.6	0.7	0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.2	0.0	0.8	0.6	0.9	0.8	0.5	0.4	0.5	0.7	1.0	0.3	0.8	0.2	0.2	0.8	0.9	0.8	0.5
Reaction Time	0.2	0.4	1.8	0.5	1.0	0.2	0.3	1.4	0.3	0.4	0.2	0.6	0.4	0.5	0.5	0.6	0.9	1.0	0.4	0.5	0.5	0.5
Neuroticism (2016)	0.2	0.3	0.6	-0.4	-0.1	-0.8	-0.7	-0.2	-0.5	-0.6	-0.7	-0.6	-0.7	-0.5	-0.6	-0.5	-0.1	-0.1	-0.6	-0.4	-0.7	-0.6
Triglycerides	0.2	0.3	0.6	0.1	-0.3	0.7	0.7	-0.1	0.7	0.7	0.7	0.1	0.6	0.5	0.2	0.5	-0.1	-0.5	0.7	0.0	0.6	0.8
Heel T-Score	0.2	1.2	2.8	0.1	-0.2	1.3	1.2	0.6	1.6	1.1	0.2	0.9	1.2	1.7	0.4	1.7	0.5	0.4	1.3	1.6	1.4	1.2
BMI	0.2	1.1	2.1	0.8	0.3	1.1	1.5	0.3	1.0	1.4	1.1	1.0	1.2	0.8	0.9	1.2	0.7	0.4	1.2	1.1	1.3	1.4
Height	0.2	3.2	5.2	-1.2	-1.3	-1.9	-1.6	-2.1	-2.1	-1.9	-1.6	-1.4	-1.8	-2.3	-1.3	-2.0	-1.6	-1.5	-2.0	-2.0	-1.8	-1.9
Hair Pigment	0.2	5.4	7.1	-2.3	-1.8	-2.3	-2.6	-1.0	-2.2	-2.6	-2.2	-2.6	-2.5	-2.1	-2.4	-2.4	-2.3	-2.1	-2.4	-2.4	-2.6	-2.7
Sensitivity / hurt feelings	0.2	0.4	1.2	0.3	0.5	0.6	0.5	1.1	0.8	0.6	0.5	0.5	0.6	0.8	0.2	0.7	0.6	0.4	0.8	0.8	0.6	0.6
Average weekly fortified wine intake	0.2	0.3	0.7	-0.7	-0.7	-0.4	-0.5	-0.8	-0.4	-0.6	-0.5	-0.5	-0.5	-0.4	-0.6	-0.4	-0.6	-0.6	-0.4	-0.4	-0.4	-0.5
High blood pressure	0.2	0.6	1.0	0.9	0.5	0.9	0.8	0.1	0.7	0.9	0.9	0.8	0.9	0.7	1.0	0.7	0.6	0.6	0.8	0.7	0.8	0.9
Medication: Levothyroxine sodium	0.2	0.4	0.9	0.1	0.1	0.7	0.7	0.7	0.7	0.7	0.3	0.5	0.7	0.9	0.2	0.9	0.4	0.3	0.8	0.9	0.7	0.8
Waist circumference	0.2	0.7	1.7	0.5	0.0	0.9	1.3	-0.2	0.7	1.0	0.7	1.1	0.9	0.7	0.6	1.1	0.7	0.3	0.9	1.1	1.2	1.1
Had other major operations	0.2	0.3	0.7	0.6	0.8	0.5	0.2	0.8	0.6	0.5	0.6	0.1	0.4	0.6	0.6	0.3	0.6	0.7	0.5	0.3	0.2	0.5
Medication: Simvastatin	0.2	0.4	0.8	-0.6	-0.2	-0.7	-0.9	-0.1	-0.6	-0.7	-0.7	-0.7	-0.7	-0.5	-0.6	-0.5	-0.4	-0.2	-0.6	-0.6	-0.7	-0.7
Time employed in main current job	0.2	0.2	0.6	-0.5	-0.4	0.0	-0.6	0.6	0.1	-0.4	-0.2	-0.8	-0.2	0.3	-0.5	-0.2	-0.7	-0.4	-0.1	-0.3	-0.4	-0.4
Worrier / anxious feelings	0.2	0.4	0.9	-0.7	-0.7	-0.6	-0.7	-0.6	-0.5	-0.7	-0.5	-1.0	-0.6	-0.6	-0.7	-0.6	-0.7	-0.8	-0.5	-0.6	-0.8	-0.6
Falls in the last year	0.2	0.3	0.5	0.5	0.3	0.6	0.6	0.4	0.6	0.6	0.6	0.4	0.5	0.5	0.4	0.5	0.5	0.3	0.6	0.5	0.6	0.7
Impedance of arm (left)	0.2	1.1	2.5	0.8	1.0	1.2	0.6	1.5	1.4	0.8	1.0	0.6	1.0	1.6	0.9	1.0	0.8	1.1	1.1	1.0	0.8	0.8
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.6	-0.8	-0.2	-0.5	-0.4	-0.3	-0.3	-0.3	-0.8	-0.3	-0.2	-0.4	-0.4	-0.7	-0.6	-0.3	-0.4	-0.5	-0.3
Tense / ‘highly strung’	0.2	0.4	0.7	-0.5	-0.2	-0.9	-0.8	-0.4	-0.7	-0.6	-0.8	-0.4	-0.7	-0.7	-0.6	-0.7	-0.3	-0.2	-0.7	-0.6	-0.6	-0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.1	0.8	1.0	0.3	0.3	0.6	0.3	0.4	0.5	0.6	0.4	0.3	0.7	0.2	0.8	1.0	0.3	0.3	0.3	0.3
Medication: Blood pressure	0.2	0.4	0.8	0.8	0.7	0.4	0.6	0.1	0.4	0.5	0.5	0.9	0.6	0.3	0.6	0.6	0.8	0.6	0.5	0.5	0.7	0.6
Suffer from ‘nerves’	0.2	0.4	1.6	-0.9	-1.1	0.0	-0.2	-0.0	0.2	-0.5	-0.3	-0.4	-0.3	0.2	-1.0	-0.2	-1.0	-1.3	-0.0	-0.1	-0.2	-0.5
Leg pain on walking	0.2	0.3	0.8	-0.6	-0.8	0.5	0.3	0.7	0.7	0.1	0.1	-0.1	0.2	0.7	-0.7	0.4	-0.6	-0.9	0.6	0.4	0.4	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	-0.5	-0.6	-0.4	-0.4	-0.8	-0.5	-0.5	-0.4	-0.6	-0.4	-0.4	-0.4	-0.4	-0.5	-0.5	-0.4	-0.4	-0.5	-0.4
Ever had bowel cancer screening	0.2	0.3	0.7	0.1	0.6	-0.8	-0.7	0.1	-0.7	-0.5	-0.7	-0.1	-0.5	-0.6	-0.1	-0.4	0.5	0.6	-0.7	-0.4	-0.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.3	-0.2	-0.5	-0.7	-0.3	-0.5	-0.4	-0.3	-0.6	-0.5	-0.5	-0.3	-0.7	-0.4	-0.2	-0.5	-0.6	-0.7	-0.5
Medication: Gliclazide	0.2	0.2	0.4	-0.4	-0.2	-0.5	-0.6	0.2	-0.5	-0.5	-0.4	-0.4	-0.5	-0.3	-0.3	-0.5	-0.6	-0.4	-0.5	-0.5	-0.4	-0.7
Number of operations (self-reported)	0.2	0.3	0.7	0.3	-0.0	0.8	0.7	0.1	0.7	0.6	0.6	0.4	0.7	0.7	0.4	0.8	0.3	0.2	0.7	0.6	0.7	0.7
Cholesterol lowering medication	0.2	0.3	0.8	-0.6	-0.6	-0.5	-0.5	-0.9	-0.6	-0.3	-0.5	-0.5	-0.5	-0.6	-0.5	-0.6	-0.5	-0.6	-0.6	-0.6	-0.5	-0.4
Worry (Nagel 2018)	0.1	0.3	0.4	-0.5	-0.4	-0.6	-0.5	-0.3	-0.5	-0.7	-0.4	-0.7	-0.6	-0.6	-0.6	-0.6	-0.5	-0.6	-0.5	-0.5	-0.6	-0.6
Prostate Cancer	0.1	0.2	0.9	-0.8	-0.9	0.1	-0.1	-0.3	-0.0	0.1	-0.3	-0.5	-0.1	0.2	-0.6	0.1	-0.6	-0.8	0.1	0.0	-0.0	0.1
LDL Cholesterol	0.1	0.1	0.5	0.1	-0.0	-0.4	0.0	-0.6	-0.4	0.1	-0.1	-0.1	-0.2	-0.7	0.1	-0.3	-0.0	-0.2	-0.4	0.0	-0.2	-0.1
Rheumatoid Arthritis	0.1	0.1	0.3	0.1	0.1	0.4	0.1	0.4	0.5	0.2	0.3	0.0	0.3	0.5	0.1	0.4	0.1	0.1	0.4	0.0	0.3	0.3
Waist Hip Ratio (WHR)	0.1	0.3	0.9	-0.8	-0.9	-0.2	-0.6	-0.5	-0.1	-0.6	-0.4	-0.9	-0.4	-0.0	-0.7	-0.3	-0.8	-0.9	-0.3	-0.3	-0.6	-0.5
Taking other prescription medications	0.1	0.1	0.9	-0.1	0.3	0.0	-0.1	0.9	0.1	0.0	-0.2	0.1	0.0	0.4	-0.2	0.3	0.4	0.4	0.1	0.3	0.1	0.1
Sitting height	0.1	0.8	1.6	1.0	0.6	0.9	1.3	0.1	0.9	1.1	1.1	1.1	1.0	0.6	1.0	0.9	0.7	0.5	0.9	0.9	1.1	1.1
Number of incorrect matches in round	0.1	0.2	0.5	-0.6	-0.7	-0.4	-0.2	-0.3	-0.6	-0.5	-0.6	-0.3	-0.4	-0.4	-0.6	-0.1	-0.4	-0.6	-0.4	-0.1	-0.2	-0.5
Nervous feelings	0.1	0.3	0.7	-0.3	0.2	-0.8	-0.7	0.2	-0.7	-0.6	-0.7	-0.2	-0.6	-0.6	-0.5	-0.5	0.0	0.1	-0.6	-0.5	-0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.8	0.3	0.2	0.8	0.6	0.4	0.9	0.5	0.9	0.3	0.6	0.7	0.3	0.5	0.1	-0.1	0.7	0.4	0.5	0.6
Financial difficulties in last 2 years	0.1	0.2	0.5	0.5	0.4	0.5	0.4	0.5	0.6	0.6	0.7	0.2	0.5	0.5	0.5	0.2	0.2	0.3	0.5	0.3	0.3	0.5
Pain all over the body in last month	0.1	0.1	0.2	-0.1	-0.3	0.3	0.2	-0.1	0.4	0.3	0.2	0.0	0.2	0.3	-0.1	0.2	-0.1	-0.3	0.3	0.2	0.2	0.3
Illnesses of siblings	0.1	0.2	0.8	-0.4	-0.9	0.4	0.4	-0.2	0.1	0.3	0.2	-0.4	0.2	0.2	-0.1	0.2	-0.6	-0.7	0.3	0.2	0.1	0.4
Trunk fat-free mass	0.1	0.7	2.3	-0.5	-0.7	-1.0	-0.2	-1.5	-1.1	-0.6	-0.8	-0.2	-0.8	-1.4	-0.6	-0.8	-0.5	-0.8	-0.9	-0.7	-0.5	-0.5
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	-0.9	-0.9	0.2	0.0	-0.1	0.4	-0.2	-0.3	-0.2	-0.0	0.5	-0.8	0.4	-0.5	-0.8	0.2	0.4	0.1	-0.1
Number of live births	0.1	0.1	0.3	-0.5	-0.5	-0.3	-0.4	-0.4	-0.4	-0.3	-0.5	-0.4	-0.3	-0.2	-0.4	-0.2	-0.4	-0.3	-0.3	-0.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	0.9	-0.4	-0.1	-0.9	-0.8	-0.8	-0.5	-0.7	-0.5	-0.6	-0.9	-0.9	-0.6	-0.9	-0.3	-0.3	-0.9	-0.8	-0.9	-0.7
Happiness	0.1	0.1	0.3	-0.3	-0.5	-0.1	-0.2	-0.5	-0.2	-0.4	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.5	-0.4	-0.3	-0.2	-0.2	-0.4
Medication: Cholesterol lowering	0.1	0.2	1.0	0.3	0.6	0.2	0.1	1.0	0.4	0.0	0.1	0.3	0.2	0.5	0.1	0.4	0.6	0.6	0.3	0.4	0.2	0.1
Prospective memory result	0.1	0.1	0.3	0.5	0.5	0.1	0.1	0.4	0.1	0.4	0.3	0.4	0.2	0.1	0.4	0.1	0.4	0.4	0.1	0.0	0.2	0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	0.1	-0.2	0.5	0.6	-0.0	0.3	0.5	0.5	-0.1	0.4	0.2	0.3	0.4	-0.0	-0.2	0.4	0.4	0.3	0.5
Trunk predicted mass	0.1	0.7	2.5	-0.6	-0.8	-0.9	-0.2	-1.6	-1.1	-0.6	-0.8	-0.2	-0.8	-1.4	-0.6	-0.8	-0.6	-0.9	-0.9	-0.7	-0.5	-0.6
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.7	-0.3	-0.4	0.6	0.0	0.7	0.7	0.1	0.3	-0.2	0.3	0.8	-0.1	0.2	-0.5	-0.2	0.4	0.2	0.1	0.1
Loud music exposure frequency	0.1	0.1	0.9	0.3	0.7	-0.1	-0.1	0.9	0.2	0.0	-0.0	0.2	-0.1	0.2	0.0	0.1	0.7	0.7	-0.0	0.2	0.0	-0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.3	-0.0	-0.3	0.4	0.6	0.1	0.2	0.4	0.2	0.2	0.4	0.3	0.1	0.5	-0.1	-0.2	0.4	0.5	0.4	0.5
Gout (self-reported)	0.1	0.1	0.6	-0.7	-0.6	-0.0	-0.2	0.2	0.1	-0.5	-0.4	-0.3	-0.2	0.1	-0.8	-0.0	-0.4	-0.6	-0.0	0.0	-0.1	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.7	0.4	0.8	0.1	0.2	0.8	0.2	0.4	0.1	0.5	0.3	0.3	0.3	0.4	0.8	0.9	0.2	0.5	0.3	0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.9	-0.5	-0.9	0.0	0.0	-0.6	-0.1	-0.1	-0.0	-0.3	-0.1	-0.1	-0.3	-0.3	-0.8	-0.9	-0.1	-0.2	-0.1	-0.1
Birth weight	0.1	0.2	0.4	-0.3	-0.0	-0.6	-0.5	-0.3	-0.4	-0.4	-0.4	-0.3	-0.5	-0.6	-0.5	-0.4	-0.1	-0.2	-0.5	-0.4	-0.4	-0.4
High blood pressure (siblings)	0.1	0.1	0.2	-0.0	0.2	-0.4	-0.4	0.0	-0.3	-0.5	-0.4	-0.0	-0.3	-0.2	-0.3	-0.3	0.1	0.1	-0.3	-0.3	-0.2	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.4	1.0	0.6	0.8	0.4	0.5	0.6	0.6	0.5	0.5	0.7	0.5	0.5	0.4	0.6	1.0	0.9	0.5	0.6	0.5	0.6
Arm fat-free mass (right)	0.1	0.4	2.2	-0.4	-0.8	-0.6	0.2	-1.5	-0.9	-0.2	-0.4	0.0	-0.4	-1.2	-0.3	-0.5	-0.5	-0.9	-0.6	-0.5	-0.2	-0.2
Pulse wave peak to peak time	0.1	0.1	0.3	-0.0	0.3	-0.5	-0.5	-0.0	-0.3	-0.4	-0.5	0.2	-0.4	-0.3	-0.2	-0.4	0.1	0.3	-0.4	-0.4	-0.2	-0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.4	-0.1	0.0	-0.5	-0.5	-0.6	-0.4	-0.5	-0.2	-0.6	-0.5	-0.7	-0.2	-0.7	-0.3	-0.2	-0.5	-0.6	-0.6	-0.6
Mean time to correctly identify matches	0.1	0.2	1.2	0.3	0.9	-0.2	-0.2	1.1	-0.1	-0.1	-0.1	0.2	-0.0	0.1	0.2	0.2	0.6	0.9	-0.0	0.1	-0.0	-0.1
Arm predicted mass (right)	0.1	0.3	1.9	-0.4	-0.8	-0.4	0.3	-1.4	-0.7	-0.1	-0.3	0.1	-0.3	-1.0	-0.3	-0.3	-0.5	-0.9	-0.4	-0.3	-0.0	-0.1
Pulse rate, automated reading	0.1	0.5	0.8	0.6	0.4	0.7	0.9	0.5	0.6	0.9	0.7	0.6	0.7	0.5	0.6	0.7	0.5	0.3	0.8	0.7	0.8	0.9
Age at last live birth	0.1	0.1	0.3	0.4	0.6	-0.4	-0.3	-0.3	-0.3	-0.2	-0.0	0.1	-0.3	-0.5	0.3	-0.4	0.2	0.4	-0.4	-0.4	-0.3	-0.3
Family relationship satisfaction	0.1	0.1	0.4	-0.5	-0.6	0.1	-0.1	0.2	0.1	-0.1	-0.2	-0.3	-0.0	0.3	-0.3	0.2	-0.4	-0.3	-0.0	0.1	-0.0	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	-0.0	0.2	-0.1	0.3	0.4	0.0	0.1	-0.1	0.5	0.1	0.1	-0.1	0.3	0.4	0.2	0.1	0.5	0.3	0.1
Supplements: Vitamin C	0.1	0.2	0.6	0.5	0.4	0.5	0.2	0.0	0.6	0.5	0.8	0.1	0.4	0.5	0.6	0.2	0.1	0.2	0.5	0.2	0.2	0.4
Whole body fat-free mass	0.1	0.6	2.2	-0.7	-0.9	-0.9	-0.2	-1.5	-1.1	-0.5	-0.8	-0.2	-0.7	-1.2	-0.7	-0.6	-0.5	-0.9	-0.8	-0.6	-0.4	-0.5
Leg fat-free mass (right)	0.1	0.5	1.5	-0.7	-0.8	-0.8	-0.2	-1.2	-0.9	-0.5	-0.9	-0.2	-0.6	-1.0	-0.8	-0.5	-0.4	-0.8	-0.7	-0.4	-0.3	-0.4
Average weekly red wine intake	0.1	0.2	1.2	-0.6	-0.9	0.0	-0.0	-1.1	-0.0	-0.2	-0.3	-0.3	-0.1	-0.0	-0.4	0.1	-0.4	-0.6	-0.1	0.1	-0.1	-0.0
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.1	-0.2	-0.3	-0.4	-0.5	-0.3	-0.2	-0.2	-0.4	-0.2	-0.3	-0.0	-0.5	-0.3	-0.1	-0.3	-0.5	-0.4	-0.2
Osteoporosis (self-reported)	0.1	0.1	0.7	0.4	0.5	0.2	-0.0	0.8	0.3	0.1	0.4	-0.0	0.1	0.2	0.3	-0.1	0.2	0.3	0.2	-0.1	-0.0	0.1
Osteoarthritis (self-reported)	0.1	0.1	0.6	0.3	0.7	-0.3	-0.3	0.5	-0.3	-0.1	-0.3	0.2	-0.1	-0.1	0.2	-0.1	0.5	0.8	-0.3	-0.1	-0.2	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.5	0.8	0.3	0.2	0.7	0.6	0.4	0.5	0.3	0.3	0.4	0.3	0.3	0.8	0.7	0.4	0.4	0.2	0.4
Whole body water mass	0.1	0.6	2.2	-0.7	-0.9	-0.9	-0.2	-1.5	-1.1	-0.5	-0.8	-0.2	-0.7	-1.2	-0.6	-0.6	-0.5	-0.9	-0.8	-0.6	-0.4	-0.5
Leg predicted mass (right)	0.1	0.4	1.3	-0.7	-0.8	-0.7	-0.1	-1.2	-0.9	-0.4	-0.8	-0.1	-0.6	-0.9	-0.7	-0.4	-0.3	-0.7	-0.6	-0.3	-0.3	-0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.3	-0.1	0.1	-0.4	-0.4	-0.5	-0.3	-0.0	-0.1	-0.3	-0.3	-0.4	-0.1	-0.4	-0.1	-0.0	-0.3	-0.4	-0.4	-0.1
Wears glasses or contact lenses	0.1	0.1	0.3	0.2	0.4	-0.1	0.2	0.4	-0.0	-0.0	-0.2	0.5	0.0	-0.1	-0.0	0.3	0.6	0.4	-0.0	0.3	0.2	0.0
Financial situation satisfaction	0.1	0.1	0.3	0.5	0.4	0.3	0.3	0.2	0.3	0.3	0.5	0.4	0.2	0.1	0.5	0.0	0.2	0.2	0.2	-0.0	0.3	0.2
High cholesterol (Self-reported)	0.1	0.2	0.4	0.3	0.4	0.4	0.2	0.6	0.4	0.4	0.3	0.3	0.4	0.6	0.4	0.4	0.4	0.5	0.4	0.4	0.3	0.3
Medication: Bendroflumethiazide	0.1	0.1	1.1	0.0	-0.4	-0.1	0.1	-1.1	-0.3	-0.1	-0.0	0.1	-0.1	-0.3	0.2	-0.2	-0.3	-0.3	-0.2	-0.2	-0.0	-0.1
Medication: Paracetamol	0.1	0.2	0.6	0.5	0.8	-0.4	-0.0	0.4	-0.5	-0.1	-0.2	0.5	-0.2	-0.4	0.4	-0.1	0.7	0.8	-0.4	-0.1	-0.0	-0.1
Medication: Atorvastatin	0.1	0.1	0.3	-0.4	-0.5	0.1	0.2	-0.1	0.1	-0.2	-0.2	0.0	-0.0	0.2	-0.4	0.0	-0.2	-0.5	0.1	0.2	0.1	-0.1
Illnesses of father: High blood pressure	0.1	0.2	0.8	-0.1	-0.1	0.6	0.2	0.7	0.7	0.3	0.4	0.1	0.4	0.9	-0.1	0.4	-0.1	-0.2	0.6	0.4	0.4	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.6	-0.7	-0.4	-0.6	-0.6	-0.0	-0.4	-0.7	-0.7	-0.6	-0.7	-0.4	-0.8	-0.4	-0.5	-0.4	-0.6	-0.4	-0.6	-0.7
Arm predicted mass (left)	0.1	0.3	1.9	-0.4	-0.8	-0.5	0.3	-1.4	-0.8	-0.2	-0.4	0.1	-0.3	-1.0	-0.3	-0.3	-0.4	-0.8	-0.4	-0.3	-0.0	-0.1
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.6	0.7	0.4	0.2	0.4	-0.4	-0.1	0.0	0.4	0.4	0.3	-0.2	0.8	0.1	0.3	0.4	0.1	0.0	0.2	0.2
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.5	0.5	0.3	-0.1	0.3	-0.7	-0.3	0.0	0.1	0.4	0.1	-0.5	0.5	0.1	0.4	0.4	-0.2	0.0	0.1	0.1
HDL Cholesterol	0.0	0.0	0.2	-0.3	-0.4	-0.1	0.1	-0.2	-0.3	0.0	-0.4	0.1	-0.1	-0.1	-0.2	-0.0	-0.2	-0.3	-0.1	0.0	0.0	-0.1
Lung FEV1/FVC ratio	0.0	0.2	1.3	-0.2	-0.7	0.0	0.3	-1.2	0.1	0.2	0.3	-0.2	-0.1	-0.4	-0.0	-0.6	-0.7	-0.7	-0.2	-0.7	-0.3	0.1
Tanning	0.0	0.2	0.8	-0.0	0.1	0.6	0.2	0.7	0.7	0.4	0.3	-0.1	0.5	0.9	0.1	0.7	0.1	0.2	0.6	0.7	0.4	0.4
Leg fat-free mass (left)	0.0	0.2	0.8	-0.3	-0.5	-0.4	0.2	-0.9	-0.6	-0.1	-0.5	0.3	-0.2	-0.7	-0.3	-0.1	-0.0	-0.4	-0.3	-0.0	0.1	-0.0
Leg predicted mass (left)	0.0	0.2	1.0	-0.4	-0.6	-0.5	0.1	-1.0	-0.7	-0.1	-0.6	0.1	-0.3	-0.7	-0.4	-0.2	-0.1	-0.5	-0.4	-0.1	-0.0	-0.1
Forced vital capacity (FVC)	0.0	0.2	0.3	-0.1	0.1	-0.5	-0.5	-0.5	-0.2	-0.4	-0.2	-0.4	-0.5	-0.6	-0.4	-0.6	-0.0	-0.1	-0.5	-0.5	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.5	0.3	0.6	0.2	0.2	0.4	0.5	0.3	0.2	0.5	0.2	0.3	0.2	0.3	0.7	0.6	0.2	0.3	0.3	0.3
Standing height	0.0	0.3	1.4	-0.3	-0.5	-0.5	-0.3	-1.2	-0.6	-0.5	-0.4	-0.3	-0.5	-0.8	-0.3	-0.6	-0.4	-0.6	-0.6	-0.6	-0.5	-0.5
Hair/balding pattern: Pattern 4	0.0	0.1	0.3	0.4	0.5	-0.4	-0.1	-0.0	-0.4	-0.2	-0.1	0.4	-0.2	-0.6	0.2	-0.3	0.4	0.4	-0.4	-0.3	-0.0	-0.2
Peak expiratory flow (PEF)	0.0	0.1	0.6	0.1	0.1	-0.3	-0.1	-0.8	-0.1	-0.3	-0.0	0.2	-0.3	-0.5	-0.0	-0.3	0.1	-0.0	-0.4	-0.2	-0.1	-0.2
Heart disease (mother)	0.0	0.1	0.4	-0.2	-0.0	-0.3	-0.1	0.2	-0.6	-0.0	-0.4	0.1	-0.2	-0.3	-0.0	-0.1	-0.1	0.1	-0.3	-0.1	-0.1	-0.1
Had major operations	0.0	0.0	0.1	0.0	-0.3	0.3	0.2	-0.2	0.1	0.3	0.3	-0.2	0.2	0.2	0.2	0.1	-0.2	-0.2	0.2	0.0	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.3	0.4	0.5	0.0	0.4	0.1	0.1	0.3	0.2	0.4	0.1	-0.1	0.2	0.1	0.6	0.4	0.1	0.2	0.2	0.3
Medication: Lisinopril	0.0	0.0	0.1	0.2	0.4	-0.0	-0.2	0.3	0.0	-0.2	0.0	-0.0	-0.1	0.1	0.2	-0.1	0.1	0.3	-0.1	-0.1	-0.1	-0.2
Basal metabolic rate	0.0	0.1	0.8	-0.1	-0.4	-0.2	0.5	-0.9	-0.4	0.1	-0.2	0.5	-0.1	-0.6	-0.1	-0.0	0.1	-0.4	-0.1	0.1	0.2	0.2
Arm fat-free mass (left)	0.0	0.2	1.7	-0.3	-0.7	-0.4	0.4	-1.3	-0.6	-0.1	-0.3	0.2	-0.2	-0.8	-0.2	-0.2	-0.3	-0.7	-0.3	-0.2	0.1	-0.0
Basal cell carcinoma (self-reported)	0.0	0.1	0.2	-0.4	-0.4	-0.0	-0.1	0.3	-0.1	-0.0	-0.2	-0.4	-0.1	0.1	-0.4	0.1	-0.2	-0.4	0.1	0.1	-0.1	0.0

Hub : Genes

C8orf40

Models

Trait associations