TWAS hub - C9orf170

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0520	0.0210	0.0041	0.030	0.020	0.023	0.022	0.027	0.00014	0.0015	0.0007	0.00095	0.00027
2	TCGA	Lung Squamous Cell Carcinoma	0.0189	0.0131	0.0090	0.007	0.004	-0.001	NA	-0.002	0.04800	0.0980	0.5200	NA	0.82000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication for hormone replacement therapy	5.6	6.3	9.9	1.7	-3.1
Serious illness, injury or assault to yourself	4.3	5.2	7.2	-1.8	2.7
Serious illness, injury or assault of a close relative in last 2 years	3.9	4.5	8.6	2.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.9	8.3	8.9	3.0	-2.8
Heel T-Score	3.8	30.2	60.4	7.8	0.3
Comparative height size at age 10	3.8	21.2	38.8	-1.9	6.2
Hearing difficulty/problems: Yes	3.5	5.4	7.8	1.7	-2.8
Height	3.4	66.0	123.2	-3.0	11.1
Diabetes (father)	3.3	4.1	4.3	-2.1	2.0
Standing height	3.2	31.3	58.1	-2.1	7.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.2	3.7	6.9	-2.6	-0.7
Alcohol drinker status: Never	3.1	3.8	7.2	-2.7	0.5
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.3	12.0	-0.7	3.5
Leg pain on walking	2.6	3.2	6.2	-2.5	-0.5
Commuting to job workplace: Car/motor vehicle	2.6	3.0	5.5	0.7	-2.3
Impedance of whole body	2.6	13.1	20.3	-2.4	4.5
Mouth/teeth dental problems: Dentures	2.5	4.2	5.0	-2.2	1.9
Medication: Blood pressure	2.5	4.3	8.7	2.9	0.1
Smoking status: Previous	2.5	3.7	7.1	-0.5	-2.7
Fractured/broken bones in last 5 years	2.5	3.3	5.6	-2.4	1.0
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	3.7	1.6	-1.9
Impedance of arm (left)	2.3	10.7	17.2	-2.1	4.1
Impedance of leg (left)	2.2	10.7	14.1	-2.7	3.8
Impedance of arm (right)	2.2	10.4	16.9	-2.0	4.1
Respiratory disease	2.1	4.7	6.8	-1.7	2.6
Current tobacco smoking	2.1	3.4	4.0	-1.6	2.0
Blood clot in the leg (DVT)	2.1	2.7	3.7	-1.3	1.9
Alcohol intake frequency.	2.1	4.8	8.1	-1.2	2.9
Ever used hormone-replacement therapy (HRT)	2.0	2.6	4.9	0.5	-2.2
Happiness	2.0	2.4	4.7	2.2	-0.3
Asthma	2.0	3.9	7.3	-0.6	2.7
Medication: Amlodipine	2.0	2.8	5.3	2.3	-0.6
Mouth/teeth dental problems: Loose teeth	2.0	2.3	4.7	-2.2	0.2
Smoking status: Current	2.0	3.2	4.2	-1.5	2.1
Basal cell carcinoma (self-reported)	2.0	2.4	4.6	2.1	-0.3
Alcohol drinker status: Previous	2.0	2.3	4.1	-0.7	2.0
Impedance of leg (right)	1.9	9.2	10.9	-2.7	3.3
High blood pressure (mother)	1.9	2.7	4.4	1.0	2.1
Chest pain or discomfort	1.9	2.8	5.5	-0.3	-2.4
Asthma (self-reported)	1.9	3.9	7.6	-0.4	2.8
Lung FEV1/FVC ratio	1.8	9.2	10.7	2.8	-3.3
Number of incorrect matches in round	1.8	2.9	5.4	2.3	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	2.9	-1.3	1.7
Schizophrenia vs Biploar Disorder	1.7	2.2	4.4	2.1	0.2
Medication for cholesterol, blood pressure or diabetes	1.7	2.8	5.2	-2.3	-0.6
Forced vital capacity (FVC), Best measure	1.7	6.3	8.9	1.9	3.0
Medication: Aspirin	1.7	2.2	4.4	-0.1	2.1
Ulcerative Colitis (UC)	1.6	3.0	3.5	-1.9	1.6
Systolic Blood Pressure	1.6	7.8	8.5	2.7	2.9
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	4.0	-0.1	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	1.8	1.4	-1.3
Osteoporosis (self-reported)	1.6	1.9	3.9	-2.0	0.1
Ever taken oral contraceptive pill	1.6	1.8	2.5	1.6	-1.0
Irritable Bowel Disease (IBD)	1.5	3.5	4.2	-2.0	1.7
Lung FVC	1.5	7.5	14.3	3.8	-0.8
Multivitamins +/- minerals	1.5	1.9	3.7	1.9	0.1
Past tobacco smoking	1.5	2.7	5.3	0.4	2.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	2.0	-1.4	-1.2
Medication: Aspirin	1.5	2.0	4.0	-0.2	2.0
Medication: Atorvastatin	1.4	1.7	2.9	1.7	0.7
Ever had prostate specific antigen (PSA) test	1.4	1.6	3.2	1.8	-0.0
Ever depressed for a whole week	1.4	1.7	2.0	-1.4	-1.2
Lupus	1.3	2.0	3.5	-1.9	0.7
Vitamin and mineral supplements	1.3	1.7	3.3	-1.8	0.4
Forced vital capacity (FVC)	1.3	5.1	6.2	2.0	2.5
Noisy workplace	1.3	1.6	3.1	-1.8	0.3
Hair/balding pattern: Pattern 4	1.3	3.1	5.5	-2.3	0.8
Suffer from ‘nerves’	1.3	2.1	4.1	-0.2	-2.0
Hypertension (Self-reported)	1.3	3.7	7.3	2.7	-0.3
Mother’s age at death	1.3	1.6	3.0	0.5	-1.7
Alzheimer’s Disease (in mother)	1.2	1.4	1.8	-1.3	1.0
Coronary Artery Disease (CAD)	1.2	1.4	2.7	1.6	0.3
HbA1C	1.2	1.3	2.4	0.3	1.6
Systolic blood pressure, automated reading	1.2	3.6	4.9	1.5	2.2
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.5	-0.3	1.6
High blood pressure	1.2	3.3	6.7	2.6	0.2
Allergy	1.2	2.7	4.8	-0.7	-2.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	6.7	2.6	1.2
Prospective memory result	1.2	1.4	2.1	-0.8	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	4.0	6.3	2.5	1.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.7	-0.4	1.6
Knee pain experienced in last month	1.2	1.9	3.6	-0.5	-1.9
Friendships satisfaction	1.2	1.4	2.2	-0.8	1.5
Medication for cholesterol	1.2	1.8	2.8	-0.9	1.7
Number of operations (self-reported)	1.2	1.7	2.4	-1.6	1.0
Hand grip strength (left)	1.1	3.0	3.4	-1.6	1.9
Trunk fat percentage	1.1	4.4	5.8	-1.8	2.4
Hayfever, allergic rhinitis or eczema	1.1	2.5	4.9	2.2	0.2
Trunk fat mass	1.1	4.6	6.8	-1.5	2.6
Alcohol usually taken with meals	1.1	1.8	2.8	1.7	0.8
Glaucoma (self-reported)	1.1	1.3	2.0	1.4	-0.8
Medication: Seretide 50 evohaler	1.1	1.3	2.3	-0.5	1.5
Wears glasses or contact lenses	1.1	1.3	2.1	-0.7	1.4
Commuting to job workplace: Public transport	1.1	1.3	1.9	1.4	-0.9
High cholesterol (Self-reported)	1.1	2.0	3.5	1.9	0.7
Smoking Status	1.0	2.3	3.8	-2.0	0.9
Allergy or Eczema	1.0	2.6	5.1	2.3	-0.1
Relative age of first facial hair	1.0	2.0	4.0	-0.0	2.0
Severe depression (siblings)	1.0	1.2	2.1	1.4	-0.5
Pack years adult smoking proportion	1.0	1.5	2.6	-0.6	1.6
Maternal smoking around birth	1.0	1.4	2.2	-0.8	1.5
Stomach or abdominal pain in last month	1.0	1.2	1.9	-1.4	0.7
Financial difficulties in last 2 years	1.0	1.3	2.6	-1.6	-0.0
Hair/balding pattern: Pattern 3	1.0	1.5	2.8	0.5	-1.7
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.1	1.8	-0.5
Medication: Paracetamol	1.0	1.7	3.4	-0.3	-1.8
Shortness of breath walking on level ground	1.0	1.2	2.3	0.4	-1.5
Number of full sisters	1.0	1.2	1.7	0.8	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.9	0.8	-1.4
Medication: Gliclazide	1.0	1.1	1.4	0.9	1.2
Hearing aid user	1.0	1.2	1.4	-1.0	-1.2
Eye problems/disorders: Glaucoma	1.0	1.2	2.2	1.5	-0.4
Ever smoked	1.0	1.8	3.6	0.2	-1.9
Vascular/heart problems diagnosed by doctor	1.0	2.6	5.3	-2.3	0.0
Verbal and Numeric Reasoning (VNR)	0.9	2.1	2.9	1.1	-1.7
Neuroticism (2016)	0.9	1.3	2.6	1.6	0.1
Ever had hysterectomy (womb removed)	0.9	1.0	1.4	-0.7	-1.2
Hair/balding pattern: Pattern 2	0.9	1.2	2.0	-1.4	-0.7
Falls in the last year	0.9	1.2	2.4	-1.5	-0.2
Number of full brothers	0.9	1.1	2.3	-0.1	-1.5
Worry too long after embarrassment	0.9	1.6	3.1	1.8	0.0
Neck or shoulder pain in last month	0.9	1.3	2.3	-0.5	1.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	2.1	0.8	-1.4
Medication: Bendroflumethiazide	0.9	1.3	2.3	1.5	-0.5
Myopia	0.9	1.3	1.7	1.3	-1.0
Ovarian Cancer	0.8	1.0	1.1	1.0	1.1
Crohns Disease (2012)	0.8	1.2	1.9	-1.4	0.7
Fasting Glucose	0.8	0.9	1.3	1.1	-0.7
Waist Hip Ratio (WHR)	0.8	3.8	6.3	-2.5	1.1
Number of treatments/medications taken	0.8	1.5	3.0	1.7	0.2
Angina	0.8	1.1	2.1	-0.1	-1.4
Hand grip strength (right)	0.8	2.1	2.6	-1.3	1.6
Hearing difficulty/problems with background noise	0.8	1.3	2.2	1.5	-0.7
Had menopause	0.8	1.0	1.9	-0.2	-1.4
Fluid intelligence score	0.8	1.6	2.7	1.6	-0.8
Birth weight of first child	0.8	1.5	2.9	-0.2	1.7
Wheeze or whistling in the chest in last year	0.8	1.5	2.9	-1.7	-0.0
Pulse wave peak to peak time	0.8	0.9	1.6	-0.5	1.3
Eye problems/disorders: None of the above	0.8	1.0	1.0	1.0	-1.0
Angina (self-reported)	0.8	1.0	2.0	-0.1	-1.4
Medication: Ibuprofen	0.8	1.0	1.9	0.1	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.8	-0.1	1.4
Pack years of smoking	0.8	1.2	2.5	-0.0	1.6
Schizophrenia (2014)	0.7	1.5	1.8	1.4	-1.0
Type 2 Diabetes (T2D) (2012)	0.7	0.8	0.9	0.9	-0.8
Cardiovascular Disease	0.7	2.4	4.7	2.2	0.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.2	-1.1	0.9
Sitting height	0.7	4.6	7.1	1.5	2.7
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	1.5	1.2	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.2	-0.4	1.5
Pulse rate	0.7	1.3	2.0	1.4	-0.7
Breastfed as a baby	0.7	0.8	1.3	1.1	-0.6
Gout (self-reported)	0.7	0.9	1.7	-0.5	1.3
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.7	-0.3	1.3
Whole body fat mass	0.7	3.0	3.9	-1.5	2.0
Had major operations	0.7	0.8	1.5	-1.2	0.4
Illnesses of father: Heart disease	0.7	1.0	2.1	-1.4	-0.1
Back pain experienced in last month	0.7	1.0	1.4	-1.2	-0.7
Osteoarthritis (self-reported)	0.7	1.0	1.9	-0.1	1.4
Primary Biliary Cirrhosis	0.6	0.9	1.2	-0.8	1.1
Ulcerative Colitis	0.6	0.9	1.2	-0.8	1.1
Sensitivity / hurt feelings	0.6	1.1	1.9	0.5	1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.1	0.6	-1.0
Chronic bronchitis/emphysema (father)	0.6	0.7	1.2	1.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.2	-0.8	1.1
Number of live births	0.6	0.9	1.2	-0.8	-1.1
Medication: Lansoprazole	0.6	0.6	1.1	0.4	-1.1
Body fat percentage	0.6	2.6	2.8	-1.5	1.7
Exposure to tobacco smoke outside home	0.6	0.8	1.6	0.1	-1.3
Qualifications: College or University degree	0.6	2.0	2.7	1.6	-1.1
Migraine (self-reported)	0.6	0.7	1.2	0.4	1.1
Medication: Allopurinol	0.6	0.7	1.5	0.0	1.2
Eye problems/disorders: Cataract	0.6	0.7	1.2	0.4	1.1
Breast cancer (self-reported)	0.6	0.7	0.8	0.9	0.8
Irritability	0.6	0.9	1.7	-1.3	-0.5
Risk taking	0.6	0.9	1.7	-1.3	-0.4
Diastolic blood pressure, automated reading	0.6	1.8	3.5	1.9	0.1
Unable to work because of sickness or disability	0.6	0.7	1.5	0.0	1.2
Alzheimer’s Disease (including proxy)	0.5	0.7	1.0	-0.5	1.0
Crohns Disease (2017)	0.5	1.2	1.7	-1.3	0.8
Major Depression (MDD)	0.5	0.6	0.9	0.6	1.0
HDL Cholesterol	0.5	0.9	1.6	-0.3	-1.3
Average weekly spirits intake	0.5	0.6	0.8	0.9	0.6
Medication: Co-codamol	0.5	0.5	0.7	-0.8	-0.7
Qualifications: CSEs or equivalent	0.5	0.7	1.2	1.1	-0.3
Had other major operations	0.5	0.6	1.3	0.1	-1.1
Qualifications: None of the above	0.5	1.0	1.1	-1.0	1.0
Medication: Ramipril	0.5	0.6	1.2	1.1	0.4
Length of working week for main job	0.5	0.5	1.0	1.0	0.3
Peak expiratory flow (PEF)	0.5	1.3	1.5	1.0	1.2
Pulse wave reflection index	0.5	0.6	1.1	0.2	-1.1
Commuting to job workplace: Walk	0.5	0.5	1.0	1.0	-0.1
Guilty feelings	0.5	0.7	1.4	-0.0	-1.2
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.9	-0.9	0.5
Alzheimer’s Disease (in father)	0.4	0.4	0.6	0.8	-0.5
Blood White Count	0.4	2.6	5.2	0.2	2.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.0	-1.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.2	1.1	-0.7
Supplements: Glucosamine	0.4	0.5	0.6	0.8	-0.7
Weight	0.4	2.0	3.2	-0.9	1.8
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.5	1.2	-0.6
Depression (self-reported)	0.4	0.5	0.5	-0.7	0.6
Comparative body size at age 10	0.4	1.2	2.2	1.5	0.4
Medication: Omeprazole	0.4	0.5	0.9	1.0	-0.3
Heart disease (mother)	0.4	0.5	0.6	-0.8	-0.6
Medication: Paracetamol	0.4	0.7	1.1	-0.5	-1.1
Medication: Lisinopril	0.4	0.6	0.9	-0.5	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.7	0.9	-0.4
Pain experienced in last month	0.4	0.7	1.4	1.2	-0.0
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.8	0.4	-1.3
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	0.1	-0.8
LDL Cholesterol	0.3	0.4	0.7	-0.4	-0.8
Supplements: Zinc	0.3	0.3	0.6	0.8	-0.2
Diabetes (mother)	0.3	0.4	0.7	-0.9	0.1
Leg fat-free mass (left)	0.3	1.6	3.0	-0.3	1.7
Age when periods started (menarche)	0.3	0.6	0.7	-0.8	0.8
Medication: Levothyroxine sodium	0.3	0.4	0.5	0.6	-0.7
Body mass index (BMI)	0.3	1.5	3.0	0.0	-1.7
Leg predicted mass (left)	0.3	1.5	3.0	-0.3	1.7
Waist circumference	0.3	1.2	1.9	-1.4	0.7
Alcohol intake versus 10 years previously	0.3	0.4	0.8	0.2	-0.9
Medication: Cholesterol lowering	0.3	0.5	1.0	1.0	0.1
Illnesses of mother	0.3	0.4	0.5	-0.6	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.5	-0.6	0.7
Arm fat-free mass (right)	0.3	1.5	2.6	-0.7	1.6
Number of children fathered	0.3	0.3	0.5	-0.4	-0.7
Emphysema/chronic bronchitis	0.3	0.4	0.4	-0.6	0.6
Medication for pain relief, constipation, heartburn	0.3	0.5	0.7	0.8	0.6
Leg fat mass (right)	0.3	1.2	1.5	-1.0	1.2
Pulse rate, automated reading	0.3	1.1	1.8	1.3	0.7
Family relationship satisfaction	0.3	0.4	0.6	0.4	0.7
Leg fat-free mass (right)	0.3	1.5	2.9	-0.1	1.7
Diabetes diagnosed by doctor	0.3	0.5	0.8	-0.5	0.9
Qualifications: nursing, teaching	0.3	0.4	0.7	0.3	0.9
Leg predicted mass (right)	0.3	1.7	3.3	-0.1	1.8
Number of self-reported non-cancer illnesses	0.3	0.5	0.6	0.8	0.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.7	-0.0	-0.8
Illnesses of father: High blood pressure	0.3	0.3	0.4	0.6	-0.6
Basal metabolic rate	0.3	1.5	2.8	-0.4	1.7
Age started oral contraceptive pill	0.3	0.4	0.8	0.9	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	0.0	-0.9
Heart disease (siblings)	0.3	0.3	0.6	-0.2	-0.8
Bipolar Disorder (2018)	0.2	0.3	0.4	0.6	-0.4
Depression (Nagel 2018)	0.2	0.4	0.5	-0.5	0.7
Worry (Nagel 2018)	0.2	0.4	0.7	-0.8	0.3
Age at First Birth	0.2	0.3	0.7	0.8	-0.1
Triglycerides	0.2	0.3	0.5	-0.1	0.7
BMI	0.2	1.1	2.2	-0.1	-1.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.5	-0.7	0.0
Townsend deprivation index at recruitment	0.2	0.3	0.6	-0.2	-0.8
Average weekly fortified wine intake	0.2	0.2	0.2	0.4	0.5
Relative age voice broke	0.2	0.3	0.6	-0.2	0.8
Medication: Atenolol	0.2	0.3	0.5	0.7	0.2
Heart attack	0.2	0.3	0.5	0.1	-0.7
Pain all over the body in last month	0.2	0.2	0.4	-0.0	-0.7
Hip circumference	0.2	0.8	0.9	-0.9	0.8
Father’s age at death	0.2	0.3	0.6	-0.8	-0.0
Worrier / anxious feelings	0.2	0.5	0.9	0.0	1.0
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	0.4	-0.5
Loud music exposure frequency	0.2	0.2	0.3	-0.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	0.8	0.3	-0.9
Leg fat percentage (right)	0.2	0.8	1.5	-1.2	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.4	0.4	-0.7
Arm predicted mass (right)	0.2	1.0	1.7	-0.5	1.3
Whole body fat-free mass	0.2	1.2	2.3	-0.2	1.5
Ever had bowel cancer screening	0.2	0.2	0.5	-0.0	0.7
Whole body water mass	0.2	1.0	2.0	-0.1	1.4
Miserableness	0.2	0.3	0.4	0.6	-0.5
Leg fat percentage (left)	0.2	0.6	1.0	-1.0	0.5
Arm fat-free mass (left)	0.2	0.8	1.7	-0.1	1.3
Commuting to job workplace: Cycle	0.2	0.3	0.3	0.5	0.6
Cholesterol lowering medication	0.2	0.3	0.4	0.5	-0.7
Leg fat mass (left)	0.2	1.0	1.3	-0.8	1.1
Arm predicted mass (left)	0.2	1.1	2.0	-0.4	1.4
Bipolar Disorder or Schizophrenia	0.1	0.3	0.6	0.8	-0.0
Schizophrenia (2018)	0.1	0.1	0.2	0.4	0.3
Breast Cancer	0.1	0.3	0.5	0.7	-0.3
Bipolar Disorder (2011)	0.1	0.1	0.3	0.0	-0.5
Mean Putamen Volume	0.1	0.1	0.1	0.3	-0.4
Neuroticism	0.1	0.1	0.3	0.5	-0.1
Chronotype (morning person)	0.1	0.3	0.5	0.7	0.4
Hair Pigment	0.1	3.6	7.2	2.7	-0.3
Tanning	0.1	0.9	1.4	-1.2	-0.7
Medication: Metformin	0.1	0.2	0.3	-0.5	0.3
Fed-up feelings	0.1	0.2	0.4	0.6	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.5	-0.0
Taking other prescription medications	0.1	0.1	0.2	-0.0	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.0	0.4
Nervous feelings	0.1	0.2	0.5	-0.0	0.7
Medication: Simvastatin	0.1	0.2	0.4	0.6	0.0
Illnesses of siblings	0.1	0.1	0.1	0.3	-0.3
Trunk fat-free mass	0.1	0.7	1.3	0.1	1.1
Time employed in main current job	0.1	0.1	0.2	0.5	0.0
Arm fat mass (right)	0.1	0.3	0.6	-0.8	0.2
Trunk predicted mass	0.1	0.8	1.6	-0.0	1.2
Exposure to tobacco smoke at home	0.1	0.2	0.3	-0.5	0.1
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	0.1	0.6
Birth weight	0.1	0.1	0.2	-0.3	-0.4
High blood pressure (siblings)	0.1	0.2	0.2	0.5	0.3
Age at first live birth	0.1	0.2	0.3	0.2	0.6
Health satisfaction	0.1	0.1	0.1	0.3	-0.2
Mean time to correctly identify matches	0.1	0.3	0.4	-0.3	-0.7
Overall health rating	0.1	0.1	0.3	-0.5	-0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.4	-0.0	-0.6
Arm fat percentage (left)	0.1	0.3	0.6	-0.8	0.1
Average weekly red wine intake	0.1	0.1	0.2	-0.2	0.4
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.3	0.1	0.6
Loneliness, isolation	0.1	0.1	0.1	-0.1	-0.3
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	0.3	0.4
Arm fat mass (left)	0.1	0.4	0.7	-0.8	0.3
Financial situation satisfaction	0.1	0.2	0.3	-0.5	0.3
Medication: Blood pressure	0.1	0.3	0.6	0.7	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.2	-0.4	-0.4
Supplements: Calcium	0.1	0.2	0.3	0.1	0.6
Depressed Affect (Nagel 2018)	0.0	0.0	0.0	-0.0	-0.0
Neuroticism (Nagel 2018)	0.0	0.1	0.2	-0.0	0.4
Reaction Time	0.0	0.0	0.1	0.3	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.1	-0.2	0.2
Blood Eosinophil Count	0.0	0.1	0.1	-0.3	0.2
Blood Platelet Count	0.0	0.3	0.6	-0.8	0.0
Blood Red Count	0.0	0.1	0.2	-0.3	0.4
Hypothyroidism (self reported)	0.0	0.0	0.0	0.1	-0.2
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.1	0.4	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.0	0.1	-0.1
Mouth/teeth dental problems	0.0	0.0	0.0	-0.0	-0.1
Diabetes (self-reported)	0.0	0.1	0.1	0.3	-0.2
Neuroticism score	0.0	0.0	0.0	-0.1	0.1
Arm fat percentage (right)	0.0	0.2	0.4	-0.6	-0.0
Lung cancer (father)	0.0	0.0	0.0	-0.2	0.2
Tense / ‘highly strung’	0.0	0.0	0.0	-0.0	-0.1
Headache pain in last month	0.0	0.0	0.1	0.1	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.1	-0.1
Age at last live birth	0.0	0.1	0.1	-0.0	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.1	0.2
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	0.1	0.1
Supplements: Vitamin C	0.0	0.0	0.0	0.1	-0.1
Mood swings	0.0	0.1	0.2	-0.1	0.4
Long-standing illness, disability or infirmity	0.0	0.1	0.1	0.3	-0.2
Mineral and other dietary supplements	0.0	0.0	0.0	-0.0	0.1
Average weekly champagne plus white wine intake	0.0	0.1	0.1	0.2	-0.3
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.1	-0.0

Hub : Genes

C9orf170

Models

Trait associations