Hub : Genes

C9orf170

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0520 0.0210 0.0041 0.030 0.020 0.023 0.022 0.027 0.00014 0.0015 0.0007 0.00095 0.00027
2 TCGA Lung Squamous Cell Carcinoma 0.0189 0.0131 0.0090 0.007 0.004 -0.001 NA -0.002 0.04800 0.0980 0.5200 NA 0.82000

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.3 0.4 0.6 -0.4
Bipolar Disorder or Schizophrenia 0.1 0.3 0.6 0.8 -0.0
Depressed Affect (Nagel 2018) 0.0 0.0 0.0 -0.0 -0.0
Depression (Nagel 2018) 0.2 0.4 0.5 -0.5 0.7
Intelligence (Savage-Jansen 2018) 0.3 1.0 1.8 0.4 -1.3
Neuroticism (Nagel 2018) 0.0 0.1 0.2 -0.0 0.4
Schizophrenia (2018) 0.1 0.1 0.2 0.4 0.3
Schizophrenia vs Biploar Disorder 1.7 2.2 4.4 2.1 0.2
Worry (Nagel 2018) 0.2 0.4 0.7 -0.8 0.3
Alzheimer’s Disease (in mother) 1.2 1.4 1.8 -1.3 1.0
Alzheimer’s Disease (in father) 0.4 0.4 0.6 0.8 -0.5
Alzheimer’s Disease (including proxy) 0.5 0.7 1.0 -0.5 1.0
Crohns Disease (2017) 0.5 1.2 1.7 -1.3 0.8
Irritable Bowel Disease (IBD) 1.5 3.5 4.2 -2.0 1.7
Ulcerative Colitis (UC) 1.6 3.0 3.5 -1.9 1.6
Major Depression (MDD) 0.5 0.6 0.9 0.6 1.0
Reaction Time 0.0 0.0 0.1 0.3 0.0
Verbal and Numeric Reasoning (VNR) 0.9 2.1 2.9 1.1 -1.7
Breast Cancer 0.1 0.3 0.5 0.7 -0.3
Ovarian Cancer 0.8 1.0 1.1 1.0 1.1
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.2 0.3 0.7 0.8 -0.1
Bipolar Disorder (2011) 0.1 0.1 0.3 0.0 -0.5
Body Mass Index (BMI) (2010) 0.3 0.4 0.7 0.1 -0.8
Coronary Artery Disease (CAD) 1.2 1.4 2.7 1.6 0.3
Crohns Disease (2012) 0.8 1.2 1.9 -1.4 0.7
Mean Putamen Volume 0.1 0.1 0.1 0.3 -0.4
Fasting Glucose 0.8 0.9 1.3 1.1 -0.7
HbA1C 1.2 1.3 2.4 0.3 1.6
HDL Cholesterol 0.5 0.9 1.6 -0.3 -1.3
LDL Cholesterol 0.3 0.4 0.7 -0.4 -0.8
Lupus 1.3 2.0 3.5 -1.9 0.7
Neuroticism (2016) 0.9 1.3 2.6 1.6 0.1
Primary Biliary Cirrhosis 0.6 0.9 1.2 -0.8 1.1
Rheumatoid Arthritis 0.0 0.0 0.1 -0.2 0.2
Schizophrenia (2014) 0.7 1.5 1.8 1.4 -1.0
Triglycerides 0.2 0.3 0.5 -0.1 0.7
Type 2 Diabetes (T2D) (2012) 0.7 0.8 0.9 0.9 -0.8
Ulcerative Colitis 0.6 0.9 1.2 -0.8 1.1
Blood Eosinophil Count 0.0 0.1 0.1 -0.3 0.2
Blood Platelet Count 0.0 0.3 0.6 -0.8 0.0
Blood Red Count 0.0 0.1 0.2 -0.3 0.4
Blood White Count 0.4 2.6 5.2 0.2 2.3
Heel T-Score 3.8 30.2 60.4 7.8 0.3
BMI 0.2 1.1 2.2 -0.1 -1.5
Height 3.4 66.0 123.2 -3.0 11.1
Waist Hip Ratio (WHR) 0.8 3.8 6.3 -2.5 1.1
Systolic Blood Pressure 1.6 7.8 8.5 2.7 2.9
Smoking Status 1.0 2.3 3.8 -2.0 0.9
Allergy or Eczema 1.0 2.6 5.1 2.3 -0.1
Cardiovascular Disease 0.7 2.4 4.7 2.2 0.4
Hypothyroidism (self reported) 0.0 0.0 0.0 0.1 -0.2
Respiratory disease 2.1 4.7 6.8 -1.7 2.6
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.1 0.4 -0.1
Lung FEV1/FVC ratio 1.8 9.2 10.7 2.8 -3.3
Lung FVC 1.5 7.5 14.3 3.8 -0.8
Neuroticism 0.1 0.1 0.3 0.5 -0.1
Chronotype (morning person) 0.1 0.3 0.5 0.7 0.4
Hair Pigment 0.1 3.6 7.2 2.7 -0.3
Tanning 0.1 0.9 1.4 -1.2 -0.7
Hand grip strength (left) 1.1 3.0 3.4 -1.6 1.9
Number of treatments/medications taken 0.8 1.5 3.0 1.7 0.2
Average weekly spirits intake 0.5 0.6 0.8 0.9 0.6
Sensitivity / hurt feelings 0.6 1.1 1.9 0.5 1.4
Frequency of depressed mood in last 2 weeks 0.7 1.0 1.2 -1.1 0.9
Hearing difficulty/problems: Yes 3.5 5.4 7.8 1.7 -2.8
Relative age of first facial hair 1.0 2.0 4.0 -0.0 2.0
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.5 -0.7 0.0
Ever used hormone-replacement therapy (HRT) 2.0 2.6 4.9 0.5 -2.2
Ever had hysterectomy (womb removed) 0.9 1.0 1.4 -0.7 -1.2
Systolic blood pressure, automated reading 1.2 3.6 4.9 1.5 2.2
Eye problems/disorders: Diabetes related eye disease 0.6 0.7 1.1 0.6 -1.0
Angina 0.8 1.1 2.1 -0.1 -1.4
Medication for hormone replacement therapy 5.6 6.3 9.9 1.7 -3.1
Vitamin and mineral supplements 1.3 1.7 3.3 -1.8 0.4
Supplements: Zinc 0.3 0.3 0.6 0.8 -0.2
Medication: Co-codamol 0.5 0.5 0.7 -0.8 -0.7
Medication: Metformin 0.1 0.2 0.3 -0.5 0.3
Diabetes (father) 3.3 4.1 4.3 -2.1 2.0
Diabetes (mother) 0.3 0.4 0.7 -0.9 0.1
Severe depression (siblings) 1.0 1.2 2.1 1.4 -0.5
Pack years adult smoking proportion 1.0 1.5 2.6 -0.6 1.6
Impedance of leg (right) 1.9 9.2 10.9 -2.7 3.3
Leg fat-free mass (left) 0.3 1.6 3.0 -0.3 1.7
Trunk fat percentage 1.1 4.4 5.8 -1.8 2.4
Hand grip strength (right) 0.8 2.1 2.6 -1.3 1.6
Townsend deprivation index at recruitment 0.2 0.3 0.6 -0.2 -0.8
Current tobacco smoking 2.1 3.4 4.0 -1.6 2.0
Average weekly fortified wine intake 0.2 0.2 0.2 0.4 0.5
Maternal smoking around birth 1.0 1.4 2.2 -0.8 1.5
Fed-up feelings 0.1 0.2 0.4 0.6 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.2 -0.5 -0.0
Relative age voice broke 0.2 0.3 0.6 -0.2 0.8
Taking other prescription medications 0.1 0.1 0.2 -0.0 0.4
Age when periods started (menarche) 0.3 0.6 0.7 -0.8 0.8
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.0 -1.0 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 1.2 1.1 -0.7
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 2.5 -0.3 1.6
Qualifications: CSEs or equivalent 0.5 0.7 1.2 1.1 -0.3
Serious illness, injury or assault to yourself 4.3 5.2 7.2 -1.8 2.7
High blood pressure 1.2 3.3 6.7 2.6 0.2
Hayfever, allergic rhinitis or eczema 1.1 2.5 4.9 2.2 0.2
Multivitamins +/- minerals 1.5 1.9 3.7 1.9 0.1
Stomach or abdominal pain in last month 1.0 1.2 1.9 -1.4 0.7
Supplements: Glucosamine 0.4 0.5 0.6 0.8 -0.7
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.2 0.0 0.4
Medication: Atenolol 0.2 0.3 0.5 0.7 0.2
Medication: Levothyroxine sodium 0.3 0.4 0.5 0.6 -0.7
Sitting height 0.7 4.6 7.1 1.5 2.7
Chronic bronchitis/emphysema (father) 0.6 0.7 1.2 1.1 -0.5
High blood pressure (mother) 1.9 2.7 4.4 1.0 2.1
Body mass index (BMI) 0.3 1.5 3.0 0.0 -1.7
Impedance of leg (left) 2.2 10.7 14.1 -2.7 3.8
Leg predicted mass (left) 0.3 1.5 3.0 -0.3 1.7
Trunk fat mass 1.1 4.6 6.8 -1.5 2.6
Waist circumference 0.3 1.2 1.9 -1.4 0.7
Number of incorrect matches in round 1.8 2.9 5.4 2.3 -0.6
Past tobacco smoking 1.5 2.7 5.3 0.4 2.3
Alcohol usually taken with meals 1.1 1.8 2.8 1.7 0.8
Nervous feelings 0.1 0.2 0.5 -0.0 0.7
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 1.2 -0.8 1.1
Hearing difficulty/problems with background noise 0.8 1.3 2.2 1.5 -0.7
Hair/balding pattern: Pattern 2 0.9 1.2 2.0 -1.4 -0.7
Had menopause 0.8 1.0 1.9 -0.2 -1.4
Had other major operations 0.5 0.6 1.3 0.1 -1.1
Forced vital capacity (FVC) 1.3 5.1 6.2 2.0 2.5
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.0 0.0 0.1 -0.1
Ever unenthusiastic/disinterested for a whole week 1.5 1.8 2.0 -1.4 -1.2
Qualifications: None of the above 0.5 1.0 1.1 -1.0 1.0
Financial difficulties in last 2 years 1.0 1.3 2.6 -1.6 -0.0
Mouth/teeth dental problems 0.0 0.0 0.0 -0.0 -0.1
Heart attack 0.2 0.3 0.5 0.1 -0.7
Allergy 1.2 2.7 4.8 -0.7 -2.2
Pain all over the body in last month 0.2 0.2 0.4 -0.0 -0.7
Diabetes (self-reported) 0.0 0.1 0.1 0.3 -0.2
Hayfever/allergic rhinitis (self-reported) 0.7 1.0 1.5 1.2 -0.7
Medication: Ramipril 0.5 0.6 1.2 1.1 0.4
Medication: Simvastatin 0.1 0.2 0.4 0.6 0.0
Fluid intelligence score 0.8 1.6 2.7 1.6 -0.8
Illnesses of siblings 0.1 0.1 0.1 0.3 -0.3
Neuroticism score 0.0 0.0 0.0 -0.1 0.1
Weight 0.4 2.0 3.2 -0.9 1.8
Impedance of arm (right) 2.2 10.4 16.9 -2.0 4.1
Arm fat percentage (right) 0.0 0.2 0.4 -0.6 -0.0
Trunk fat-free mass 0.1 0.7 1.3 0.1 1.1
Hip circumference 0.2 0.8 0.9 -0.9 0.8
Time employed in main current job 0.1 0.1 0.2 0.5 0.0
Alcohol intake versus 10 years previously 0.3 0.4 0.8 0.2 -0.9
Father’s age at death 0.2 0.3 0.6 -0.8 -0.0
Worrier / anxious feelings 0.2 0.5 0.9 0.0 1.0
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 2.2 -0.4 1.5
Falls in the last year 0.9 1.2 2.4 -1.5 -0.2
Hair/balding pattern: Pattern 3 1.0 1.5 2.8 0.5 -1.7
Number of live births 0.6 0.9 1.2 -0.8 -1.1
Forced expiratory volume in 1-second (FEV1) 1.2 4.0 6.7 2.6 1.2
Pulse rate 0.7 1.3 2.0 1.4 -0.7
Happiness 2.0 2.4 4.7 2.2 -0.3
Noisy workplace 1.3 1.6 3.1 -1.8 0.3
Qualifications: A levels/AS levels or equivalent 0.4 0.9 1.5 1.2 -0.6
Serious illness, injury or assault of a close relative in last 2 years 3.9 4.5 8.6 2.9 -0.7
Mouth/teeth dental problems: Dentures 2.5 4.2 5.0 -2.2 1.9
Asthma 2.0 3.9 7.3 -0.6 2.7
Medication: Ibuprofen (e.g. Nurofen) 1.6 2.0 4.0 -0.1 -2.0
Medication: Cholesterol lowering 0.3 0.5 1.0 1.0 0.1
Depression (self-reported) 0.4 0.5 0.5 -0.7 0.6
Medication: Lansoprazole 0.6 0.6 1.1 0.4 -1.1
Prospective memory result 1.2 1.4 2.1 -0.8 1.5
Lung cancer (father) 0.0 0.0 0.0 -0.2 0.2
Illnesses of mother 0.3 0.4 0.5 -0.6 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.2 4.0 6.3 2.5 1.3
Pulse wave Arterial Stiffness index 0.2 0.2 0.3 0.4 -0.5
Impedance of arm (left) 2.3 10.7 17.2 -2.1 4.1
Arm fat mass (right) 0.1 0.3 0.6 -0.8 0.2
Trunk predicted mass 0.1 0.8 1.6 -0.0 1.2
Standing height 3.2 31.3 58.1 -2.1 7.6
Length of working week for main job 0.5 0.5 1.0 1.0 0.3
Exposure to tobacco smoke at home 0.1 0.2 0.3 -0.5 0.1
Breastfed as a baby 0.7 0.8 1.3 1.1 -0.6
Tense / ‘highly strung’ 0.0 0.0 0.0 -0.0 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 0.5 -0.6 0.7
Hair/balding pattern: Pattern 4 1.3 3.1 5.5 -2.3 0.8
Birth weight of first child 0.8 1.5 2.9 -0.2 1.7
Peak expiratory flow (PEF) 0.5 1.3 1.5 1.0 1.2
Pulse wave reflection index 0.5 0.6 1.1 0.2 -1.1
Ever highly irritable/argumentative for 2 days 0.1 0.2 0.3 0.1 0.6
Loud music exposure frequency 0.2 0.2 0.3 -0.2 -0.5
Qualifications: O levels/GCSEs or equivalent 1.0 1.6 3.1 1.8 -0.5
Mouth/teeth dental problems: Bleeding gums 2.4 3.1 3.7 1.6 -1.9
Blood clot in the leg (DVT) 2.1 2.7 3.7 -1.3 1.9
Medication: Paracetamol 1.0 1.7 3.4 -0.3 -1.8
Headache pain in last month 0.0 0.0 0.1 0.1 -0.3
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 5.2 -2.3 -0.6
Glaucoma (self-reported) 1.1 1.3 2.0 1.4 -0.8
Gout (self-reported) 0.7 0.9 1.7 -0.5 1.3
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 0.8 0.3 -0.9
Medication: Amlodipine 2.0 2.8 5.3 2.3 -0.6
Medication: Ventolin 100micrograms inhaler 0.7 0.9 1.7 -0.3 1.3
Birth weight 0.1 0.1 0.2 -0.3 -0.4
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.7 -0.4 1.6
High blood pressure (siblings) 0.1 0.2 0.2 0.5 0.3
Forced vital capacity (FVC), Best measure 1.7 6.3 8.9 1.9 3.0
Body fat percentage 0.6 2.6 2.8 -1.5 1.7
Leg fat percentage (right) 0.2 0.8 1.5 -1.2 0.5
Arm fat-free mass (right) 0.3 1.5 2.6 -0.7 1.6
Exposure to tobacco smoke outside home 0.6 0.8 1.6 0.1 -1.3
Comparative body size at age 10 0.4 1.2 2.2 1.5 0.4
Number of full brothers 0.9 1.1 2.3 -0.1 -1.5
Worry too long after embarrassment 0.9 1.6 3.1 1.8 0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.0 0.0 0.0 -0.1 -0.1
Wheeze or whistling in the chest in last year 0.8 1.5 2.9 -1.7 -0.0
Number of children fathered 0.3 0.3 0.5 -0.4 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.4 0.4 -0.7
Age at first live birth 0.1 0.2 0.3 0.2 0.6
Pulse wave peak to peak time 0.8 0.9 1.6 -0.5 1.3
Health satisfaction 0.1 0.1 0.1 0.3 -0.2
Shortness of breath walking on level ground 1.0 1.2 2.3 0.4 -1.5
Qualifications: College or University degree 0.6 2.0 2.7 1.6 -1.1
Eye problems/disorders: None of the above 0.8 1.0 1.0 1.0 -1.0
Mouth/teeth dental problems: Loose teeth 2.0 2.3 4.7 -2.2 0.2
Emphysema/chronic bronchitis 0.3 0.4 0.4 -0.6 0.6
Medication for pain relief, constipation, heartburn 0.3 0.5 0.7 0.8 0.6
Neck or shoulder pain in last month 0.9 1.3 2.3 -0.5 1.5
Medication: Blood pressure 2.5 4.3 8.7 2.9 0.1
Angina (self-reported) 0.8 1.0 2.0 -0.1 -1.4
Migraine (self-reported) 0.6 0.7 1.2 0.4 1.1
Medication: Ibuprofen 0.8 1.0 1.9 0.1 -1.4
Medication: Allopurinol 0.6 0.7 1.5 0.0 1.2
Medication: Omeprazole 0.4 0.5 0.9 1.0 -0.3
Medication: Seretide 50 evohaler 1.1 1.3 2.3 -0.5 1.5
Mean time to correctly identify matches 0.1 0.3 0.4 -0.3 -0.7
Heart disease (mother) 0.4 0.5 0.6 -0.8 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 1.8 -0.1 1.4
Whole body fat mass 0.7 3.0 3.9 -1.5 2.0
Leg fat mass (right) 0.3 1.2 1.5 -1.0 1.2
Arm predicted mass (right) 0.2 1.0 1.7 -0.5 1.3
Pulse rate, automated reading 0.3 1.1 1.8 1.3 0.7
Alcohol intake frequency. 2.1 4.8 8.1 -1.2 2.9
Comparative height size at age 10 3.8 21.2 38.8 -1.9 6.2
Number of full sisters 1.0 1.2 1.7 0.8 -1.3
Suffer from ‘nerves’ 1.3 2.1 4.1 -0.2 -2.0
Overall health rating 0.1 0.1 0.3 -0.5 -0.1
Chest pain or discomfort 1.9 2.8 5.5 -0.3 -2.4
Had major operations 0.7 0.8 1.5 -1.2 0.4
Age at last live birth 0.0 0.1 0.1 -0.0 0.4
Family relationship satisfaction 0.3 0.4 0.6 0.4 0.7
Leg pain on walking 2.6 3.2 6.2 -2.5 -0.5
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.0 0.0 0.1 0.2
Commuting to job workplace: Car/motor vehicle 2.6 3.0 5.5 0.7 -2.3
Illness, injury, bereavement, stress in last 2 years 0.0 0.0 0.0 0.1 0.1
Medication: Aspirin 1.5 2.0 4.0 -0.2 2.0
Supplements: Vitamin C 0.0 0.0 0.0 0.1 -0.1
Knee pain experienced in last month 1.2 1.9 3.6 -0.5 -1.9
Hypertension (Self-reported) 1.3 3.7 7.3 2.7 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 3.2 3.7 6.9 -2.6 -0.7
Illnesses of father: Heart disease 0.7 1.0 2.1 -1.4 -0.1
Illnesses of siblings: Diabetes 0.1 0.2 0.4 -0.0 -0.6
Smoking status: Previous 2.5 3.7 7.1 -0.5 -2.7
Forced expiratory volume in 1-second (FEV1), predicted 3.0 6.3 12.0 -0.7 3.5
Whole body fat-free mass 0.2 1.2 2.3 -0.2 1.5
Leg fat-free mass (right) 0.3 1.5 2.9 -0.1 1.7
Arm fat percentage (left) 0.1 0.3 0.6 -0.8 0.1
Average weekly red wine intake 0.1 0.1 0.2 -0.2 0.4
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.3 0.1 0.6
Mood swings 0.0 0.1 0.2 -0.1 0.4
Loneliness, isolation 0.1 0.1 0.1 -0.1 -0.3
Long-standing illness, disability or infirmity 0.0 0.1 0.1 0.3 -0.2
Ever had bowel cancer screening 0.2 0.2 0.5 -0.0 0.7
Diabetes diagnosed by doctor 0.3 0.5 0.8 -0.5 0.9
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 1.8 1.4 -1.3
Friendships satisfaction 1.2 1.4 2.2 -0.8 1.5
Qualifications: nursing, teaching 0.3 0.4 0.7 0.3 0.9
Commuting to job workplace: Walk 0.5 0.5 1.0 1.0 -0.1
Eye problems/disorders: Cataract 0.6 0.7 1.2 0.4 1.1
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 2.1 0.8 -1.4
Medication for cholesterol 1.2 1.8 2.8 -0.9 1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 1.9 0.8 -1.4
Back pain experienced in last month 0.7 1.0 1.4 -1.2 -0.7
Mineral and other dietary supplements 0.0 0.0 0.0 -0.0 0.1
Breast cancer (self-reported) 0.6 0.7 0.8 0.9 0.8
Asthma (self-reported) 1.9 3.9 7.6 -0.4 2.8
Osteoporosis (self-reported) 1.6 1.9 3.9 -2.0 0.1
Osteoarthritis (self-reported) 0.7 1.0 1.9 -0.1 1.4
Medication: Aspirin 1.7 2.2 4.4 -0.1 2.1
Medication: Gliclazide 1.0 1.1 1.4 0.9 1.2
Illnesses of father: None of the above (group 1) 0.1 0.1 0.1 0.3 0.4
Smoking status: Current 2.0 3.2 4.2 -1.5 2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.9 8.3 8.9 3.0 -2.8
Whole body water mass 0.2 1.0 2.0 -0.1 1.4
Leg predicted mass (right) 0.3 1.7 3.3 -0.1 1.8
Arm fat mass (left) 0.1 0.4 0.7 -0.8 0.3
Number of self-reported non-cancer illnesses 0.3 0.5 0.6 0.8 0.7
Average weekly champagne plus white wine intake 0.0 0.1 0.1 0.2 -0.3
Miserableness 0.2 0.3 0.4 0.6 -0.5
Guilty feelings 0.5 0.7 1.4 -0.0 -1.2
Wears glasses or contact lenses 1.1 1.3 2.1 -0.7 1.4
Ever taken oral contraceptive pill 1.6 1.8 2.5 1.6 -1.0
Hearing aid user 1.0 1.2 1.4 -1.0 -1.2
Mother’s age at death 1.3 1.6 3.0 0.5 -1.7
Financial situation satisfaction 0.1 0.2 0.3 -0.5 0.3
Tinnitus: Yes, now most or all of the time 0.3 0.3 0.7 -0.0 -0.8
Commuting to job workplace: Public transport 1.1 1.3 1.9 1.4 -0.9
Eye problems/disorders: Glaucoma 1.0 1.2 2.2 1.5 -0.4
Medication: Blood pressure 0.1 0.3 0.6 0.7 -0.1
Pain type(s) experienced in last month: Hip pain 0.5 0.6 0.9 -0.9 0.5
Supplements: Fish oil (including cod liver oil) 0.0 0.0 0.0 -0.1 -0.0
High cholesterol (Self-reported) 1.1 2.0 3.5 1.9 0.7
Medication: Bendroflumethiazide 0.9 1.3 2.3 1.5 -0.5
Medication: Paracetamol 0.4 0.7 1.1 -0.5 -1.1
Medication: Lisinopril 0.4 0.6 0.9 -0.5 -1.0
Medication: Atorvastatin 1.4 1.7 2.9 1.7 0.7
Illnesses of father: High blood pressure 0.3 0.3 0.4 0.6 -0.6
Alcohol drinker status: Never 3.1 3.8 7.2 -2.7 0.5
Ever smoked 1.0 1.8 3.6 0.2 -1.9
Basal metabolic rate 0.3 1.5 2.8 -0.4 1.7
Leg fat percentage (left) 0.2 0.6 1.0 -1.0 0.5
Arm fat-free mass (left) 0.2 0.8 1.7 -0.1 1.3
Number of operations (self-reported) 1.2 1.7 2.4 -1.6 1.0
Average weekly beer plus cider intake 0.1 0.2 0.2 -0.4 -0.4
Irritability 0.6 0.9 1.7 -1.3 -0.5
Risk taking 0.6 0.9 1.7 -1.3 -0.4
Ever had prostate specific antigen (PSA) test 1.4 1.6 3.2 1.8 -0.0
Fractured/broken bones in last 5 years 2.5 3.3 5.6 -2.4 1.0
Age started oral contraceptive pill 0.3 0.4 0.8 0.9 0.1
Diastolic blood pressure, automated reading 0.6 1.8 3.5 1.9 0.1
Ever depressed for a whole week 1.4 1.7 2.0 -1.4 -1.2
Unable to work because of sickness or disability 0.6 0.7 1.5 0.0 1.2
Commuting to job workplace: Cycle 0.2 0.3 0.3 0.5 0.6
Myopia 0.9 1.3 1.7 1.3 -1.0
Vascular/heart problems diagnosed by doctor 1.0 2.6 5.3 -2.3 0.0
Cholesterol lowering medication 0.2 0.3 0.4 0.5 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.7 0.9 -0.4
Pain experienced in last month 0.4 0.7 1.4 1.2 -0.0
Supplements: Calcium 0.1 0.2 0.3 0.1 0.6
Basal cell carcinoma (self-reported) 2.0 2.4 4.6 2.1 -0.3
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.8 0.0 -0.9
Deep venous thrombosis (DVT) (self-reported) 1.8 2.3 2.9 -1.3 1.7
Heart disease (siblings) 0.3 0.3 0.6 -0.2 -0.8
Alcohol drinker status: Previous 2.0 2.3 4.1 -0.7 2.0
Pack years of smoking 0.8 1.2 2.5 -0.0 1.6
Impedance of whole body 2.6 13.1 20.3 -2.4 4.5
Leg fat mass (left) 0.2 1.0 1.3 -0.8 1.1
Arm predicted mass (left) 0.2 1.1 2.0 -0.4 1.4