Hub : Genes

CAB39L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3480 0.0480 0.0e+00 0.240 0.260 0.315 0.310 0.306 7.3e-29 1.7e-31 4.2e-39 2.0e-38 7.2e-38
2 GTEx Artery Aorta 0.1350 0.0610 3.6e-03 0.008 NA -0.002 NA 0.005 1.1e-01 NA 4.0e-01 NA 1.5e-01
3 GTEx Brain Caudate basal ganglia 0.2560 0.1020 5.5e-03 0.132 NA 0.013 NA 0.069 1.3e-04 NA 1.3e-01 NA 5.0e-03
4 GTEx Brain Cerebellum 0.3460 0.0960 2.6e-06 0.116 NA 0.213 NA 0.165 2.7e-04 NA 6.3e-07 NA 1.3e-05
5 GTEx Brain Cortex 0.3960 0.1080 5.7e-04 0.151 NA 0.028 NA 0.039 5.8e-05 NA 5.6e-02 NA 3.0e-02
6 GTEx Brain Nucleus accumbens basal ganglia 0.2550 0.1180 6.0e-03 0.026 NA -0.008 NA 0.010 6.7e-02 NA 6.1e-01 NA 1.7e-01
7 GTEx Cells Transformed fibroblasts 0.3370 0.0680 1.4e-11 0.079 NA 0.125 NA 0.099 1.6e-06 NA 1.3e-09 NA 6.9e-08
8 GTEx Heart Atrial Appendage 0.2410 0.0810 1.8e-03 0.001 NA 0.002 NA 0.012 2.9e-01 NA 2.4e-01 NA 9.1e-02
9 GTEx Skin Sun Exposed Lower leg 0.0600 0.0260 3.1e-03 0.042 NA 0.032 NA 0.040 1.9e-04 NA 9.9e-04 NA 2.6e-04
10 METSIM Adipose 0.0422 0.0168 2.3e-04 0.001 0.032 0.019 0.029 0.010 1.8e-01 1.3e-05 5.9e-04 2.7e-05 9.7e-03
11 TCGA Kidney Renal Clear Cell Carcinoma 0.1294 0.0364 5.7e-15 0.135 0.146 0.136 NA 0.136 5.7e-15 4.4e-16 4.9e-15 NA 4.2e-15
12 TCGA Kidney Renal Papillary Cell Carcinoma 0.0890 0.0470 2.5e-03 0.020 0.055 0.020 NA 0.016 2.5e-02 4.1e-04 2.3e-02 NA 3.8e-02
13 TCGA Lung Squamous Cell Carcinoma 0.0289 0.0156 5.0e-03 -0.002 0.010 -0.002 NA -0.001 6.7e-01 2.2e-02 9.4e-01 NA 5.1e-01
14 TCGA Ovarian Serous Cystadenocarcinoma 0.1570 0.0650 2.9e-03 0.018 0.013 0.027 NA 0.008 2.0e-02 4.1e-02 6.0e-03 NA 8.2e-02
15 TCGA Pancreatic Adenocarcinoma 0.1190 0.0600 4.2e-03 0.123 0.045 0.090 NA 0.111 8.0e-06 5.7e-03 1.3e-04 NA 2.3e-05
16 TCGA Thyroid Carcinoma 0.1450 0.0460 2.3e-08 0.068 0.079 0.075 NA 0.061 3.8e-07 3.9e-08 8.6e-08 NA 1.3e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bipolar Disorder (2018) 0.7 1.0 5.7 -1.6 -1.1 -0.8 2.4 -1.5 -0.5 0.1 -0.7 0.9 0.5 1.0 1.0 -0.2 0.6 0.4 -0.1
Bipolar Disorder or Schizophrenia 0.5 1.1 5.8 -1.1 -1.5 -1.8 2.4 -0.7 -0.7 -0.7 -0.3 0.5 -0.3 0.2 0.2 -1.4 1.0 0.2 -0.4
Depressed Affect (Nagel 2018) 0.9 2.0 6.5 -1.0 -1.5 0.2 -0.4 -0.4 1.0 -1.4 -1.0 -2.6 -1.1 -2.1 -2.2 -0.5 -1.6 -0.9 -1.9
Depression (Nagel 2018) 0.2 0.3 1.6 0.0 0.2 0.9 -0.5 0.0 1.3 -0.0 0.2 -0.7 0.3 -0.8 -0.6 0.5 -0.2 -0.1 -0.4
Intelligence (Savage-Jansen 2018) 1.4 4.3 15.8 2.3 2.7 -0.0 -1.7 0.6 -1.2 -1.4 4.0 -3.8 0.9 -0.8 -1.5 -1.8 1.9 -3.0 -1.0
Neuroticism (Nagel 2018) 0.9 2.2 6.6 -0.5 -1.1 0.7 -0.6 -0.8 1.4 -2.0 -0.9 -2.6 -0.4 -2.3 -2.1 -0.1 -1.5 -1.7 -1.7
Schizophrenia (2018) 0.4 0.7 3.0 -0.1 -1.1 -1.7 1.1 0.4 -0.5 -1.1 0.2 -0.1 -0.7 -0.5 -0.6 -1.6 0.8 -0.1 -0.5
Schizophrenia vs Biploar Disorder 1.1 1.5 3.8 1.6 1.9 -1.6 -0.3 0.3 -1.7 0.1 1.8 -0.1 1.4 -0.7 -0.5 -1.4 1.7 -0.8 -0.5
Worry (Nagel 2018) 0.8 1.8 4.1 -0.9 -1.4 0.8 -0.2 -1.2 1.4 -1.9 -1.6 -2.0 -0.4 -1.7 -1.6 -0.1 -1.2 -1.7 -1.3
Alzheimer’s Disease (in mother) 2.6 3.0 12.1 0.0 -0.6 -1.4 2.6 -0.8 -0.3 2.4 3.5 2.7 1.3 1.5 2.0 0.4 0.4 1.4 1.6
Alzheimer’s Disease (in father) 0.3 0.3 2.1 0.2 0.3 0.5 0.1 0.1 1.5 -0.0 -1.3 0.3 0.4 0.1 0.1 0.7 0.5 0.1 0.4
Alzheimer’s Disease (including proxy) 1.4 2.0 7.3 0.0 -0.4 -1.7 2.7 -1.5 -0.2 1.8 1.9 1.9 1.2 1.1 1.2 0.0 0.9 1.1 1.5
Crohns Disease (2017) 0.9 2.1 8.1 -1.1 -1.1 -0.5 1.2 -0.6 -0.0 0.9 -0.4 2.7 -1.0 1.8 1.9 1.0 0.7 2.9 1.8
Irritable Bowel Disease (IBD) 0.6 1.3 5.2 -1.8 -1.6 -0.9 1.1 -0.2 -1.1 -0.4 -2.3 1.3 -1.6 0.2 -0.2 -0.8 -0.5 1.3 -0.2
Ulcerative Colitis (UC) 1.3 2.5 8.8 -1.7 -1.6 -1.6 1.1 -0.2 -2.4 -0.9 -3.0 -0.1 -1.1 -0.9 -1.7 -2.5 -1.3 -0.3 -1.8
Major Depression (MDD) 1.3 1.6 4.0 0.1 0.0 0.6 -1.2 -0.2 0.7 -1.8 -0.2 -2.0 -1.3 -1.7 -1.7 -1.1 -1.0 -1.3 -1.8
Reaction Time 0.2 0.4 1.9 0.3 -0.3 0.2 -0.7 0.7 0.2 -0.5 -1.4 -0.4 0.3 -0.8 -0.4 -0.4 -0.4 -0.8 -0.9
Verbal and Numeric Reasoning (VNR) 2.0 4.8 23.7 3.5 3.5 1.0 -2.0 1.2 -0.5 -0.4 4.9 -2.6 1.9 -0.5 -0.6 -0.7 1.9 -2.5 -0.4
Breast Cancer 0.2 0.4 2.5 -0.1 0.6 1.1 0.3 0.3 0.9 0.2 0.1 0.1 0.6 0.6 0.9 1.6 -0.6 -0.2 0.3
Ovarian Cancer 0.4 0.5 1.8 0.2 -0.4 -1.3 -0.0 0.4 -0.9 0.6 -1.3 -0.9 0.4 1.1 0.1 -0.8 0.3 -0.2 -0.4
Prostate Cancer 0.4 0.6 1.8 -0.2 -0.6 -1.3 0.5 -0.2 -1.3 -0.3 0.3 -1.2 -1.0 0.0 -0.4 -1.3 -0.9 -0.7 -0.2
Age at First Birth 0.4 0.6 2.1 -0.1 0.3 1.1 -0.4 -0.1 1.3 -1.4 0.7 -0.6 -0.4 -0.4 -0.4 -0.4 0.5 -1.5 -0.6
Bipolar Disorder (2011) 1.2 1.2 5.4 -2.0 -2.3 -0.8 1.5 -1.2 -0.1 -0.8 0.7 -0.0 -1.1 0.4 -0.0 -1.3 0.5 -0.1 -0.8
Body Mass Index (BMI) (2010) 0.2 0.3 1.1 -1.1 -0.6 -0.7 0.2 -0.5 -0.9 -0.5 0.7 0.4 -1.0 0.4 0.1 -0.2 0.1 -0.3 -0.2
Coronary Artery Disease (CAD) 1.6 1.9 6.2 -0.1 -0.4 0.1 -0.2 1.1 -0.5 1.3 0.9 2.5 1.4 2.1 2.0 1.4 1.5 1.7 1.8
Crohns Disease (2012) 0.7 1.1 3.7 -0.6 -0.1 -0.9 0.8 -0.2 -0.1 0.7 -0.6 1.9 -1.4 1.2 1.4 0.4 0.4 1.9 1.4
Mean Putamen Volume 1.5 1.7 8.4 1.7 1.3 0.2 -1.7 1.3 -0.2 -1.1 -0.9 -2.9 -0.7 -0.6 -1.8 -0.2 1.0 -1.5 -0.4
Fasting Glucose 0.3 0.4 1.9 0.8 1.4 0.2 -1.0 0.5 0.1 -0.3 0.6 -0.0 0.5 -0.1 -0.4 0.5 0.7 -0.5 -0.4
HbA1C 0.4 0.5 2.5 0.4 -0.6 -0.1 0.2 0.3 0.7 -0.5 -1.6 1.0 -0.1 -1.1 -1.0 0.4 0.3 0.3 0.0
HDL Cholesterol 0.2 0.4 1.8 -0.2 -0.7 -0.2 -0.4 0.2 0.0 0.9 0.5 -0.2 0.2 1.3 0.9 0.2 1.3 0.6 -0.0
LDL Cholesterol 0.3 0.5 1.3 -0.4 -0.6 -0.8 1.0 -0.6 -0.0 0.1 0.2 1.2 -1.1 0.1 0.0 -0.7 0.6 0.8 0.9
Lupus 1.0 1.6 4.2 -1.0 -0.5 1.5 0.4 -0.2 1.8 -1.8 -0.5 -0.0 -1.7 -1.7 -1.1 0.7 -2.0 -0.7 -1.5
Neuroticism (2016) 1.1 1.5 4.8 0.8 0.2 0.8 -1.8 0.1 1.4 -1.4 -0.4 -1.4 -1.3 -2.2 -1.7 0.5 -1.5 -1.0 -0.8
Primary Biliary Cirrhosis 1.0 1.4 9.3 -1.0 -0.5 0.3 1.5 -0.5 0.3 0.5 -3.1 1.5 -0.4 0.4 0.7 1.3 -0.6 1.8 1.1
Rheumatoid Arthritis 1.3 1.7 6.4 1.6 0.7 1.9 -2.0 1.9 2.5 0.3 -0.8 0.3 -0.4 0.7 1.0 1.8 0.7 0.6 1.1
Schizophrenia (2014) 0.8 1.8 7.2 -1.4 -2.0 -2.7 2.3 -0.8 -0.9 -1.2 -0.0 0.3 -1.5 -0.7 -0.8 -2.0 0.0 0.1 -0.6
Triglycerides 0.5 0.8 3.5 1.9 1.4 0.5 -1.2 0.7 -0.1 -0.4 -0.4 -0.3 0.8 -0.9 -0.8 -0.0 0.6 -1.5 0.1
Type 2 Diabetes (T2D) (2012) 2.4 2.7 6.9 -1.2 -1.4 0.2 -0.7 -0.6 0.4 -2.6 -1.4 -2.6 -2.6 -1.9 -2.3 -1.4 -0.4 -1.7 -1.8
Ulcerative Colitis 1.2 1.8 4.0 -1.0 -0.0 -1.6 -0.0 -0.6 -1.8 -1.6 -1.9 -0.6 -1.7 -1.2 -1.7 -2.0 -0.9 -1.0 -1.3
Blood Eosinophil Count 0.7 5.3 11.4 -1.4 -1.7 0.7 -2.2 -0.5 -1.0 -2.5 -3.3 -3.3 -3.0 -2.7 -3.1 -1.3 -2.5 -0.8 -3.4
Blood Platelet Count 0.8 9.4 29.5 0.7 0.9 -0.0 -1.6 -0.2 -1.3 -2.2 0.4 -4.4 -1.8 -4.5 -5.4 -3.2 -1.7 -5.4 -5.0
Blood Red Count 0.2 2.1 11.2 -2.7 -3.3 -0.5 1.2 -0.8 -0.2 -1.0 -2.7 0.9 -0.6 -0.5 -1.1 -0.6 -1.1 0.3 -1.0
Blood White Count 0.9 6.5 18.0 0.5 0.6 -2.1 -2.0 0.7 -3.3 -0.9 -1.4 -3.9 -1.4 -2.9 -4.2 -3.7 -1.0 -3.4 -3.3
Heel T-Score 0.5 4.3 15.5 1.4 -0.5 1.6 1.4 2.3 2.6 0.8 -3.9 1.4 2.0 1.8 1.2 2.9 1.4 1.4 3.2
BMI 0.6 3.8 7.5 -1.6 -1.1 -2.6 0.5 -2.1 -1.8 -2.7 0.4 -0.8 -2.4 -1.9 -1.3 -2.5 -2.4 -2.3 -2.2
Height 0.3 6.6 21.3 1.7 3.7 2.8 -4.6 0.5 1.4 -1.5 4.1 -4.1 -3.6 0.1 1.2 1.8 1.7 0.4 -1.2
Waist Hip Ratio (WHR) 1.2 5.3 17.8 -0.1 0.1 4.2 -2.6 3.3 3.1 -2.0 -2.8 -2.8 -2.4 -1.1 -2.0 1.8 -1.5 -1.4 -1.6
Systolic Blood Pressure 0.8 4.2 13.0 2.2 2.3 2.7 -3.6 2.2 2.3 -1.7 0.2 -2.7 -1.3 -2.0 -2.2 1.7 -0.5 -1.8 -0.1
Smoking Status 0.4 1.0 3.7 1.9 1.0 0.3 -1.7 1.5 0.3 0.4 0.7 0.4 1.9 -0.2 -0.2 -0.3 0.7 -0.8 -0.9
Allergy or Eczema 0.8 2.1 4.5 0.7 1.3 0.8 -0.6 1.0 -0.2 1.9 2.1 2.0 0.2 1.6 1.8 1.9 1.8 1.6 1.4
Cardiovascular Disease 1.2 4.0 11.2 0.3 0.6 0.8 -1.8 1.0 1.8 -3.3 -1.1 -2.9 -2.8 -3.1 -3.0 -0.1 -0.9 -2.0 -1.6
Hypothyroidism (self reported) 0.2 0.5 2.7 0.6 0.5 0.0 -1.0 -0.5 -0.5 0.5 -1.6 0.1 0.2 -0.1 -0.2 -0.4 1.3 0.8 -0.8
Respiratory disease 0.4 1.0 6.5 -1.4 -0.8 -1.2 0.2 -1.8 -0.7 -0.3 -0.2 0.3 -2.5 0.3 0.2 -0.5 0.2 0.7 0.4
Type 2 Diabetes (T2D) (2018) 0.5 0.9 4.0 -1.1 -1.5 -0.3 -0.4 -0.5 0.2 -1.5 -2.0 -0.6 -0.9 -0.6 -0.7 -0.7 -1.0 -0.3 -0.6
Lung FEV1/FVC ratio 0.2 0.8 4.6 -0.6 -0.2 -0.7 -0.5 -0.4 -0.0 0.7 2.1 0.3 -1.0 0.8 1.3 0.5 0.1 1.4 1.1
Lung FVC 2.7 13.8 34.7 -3.0 -1.2 -2.9 -0.1 -3.6 -3.4 -4.0 3.5 -2.9 -0.6 -4.5 -4.7 -5.3 -2.3 -5.9 -5.5
Neuroticism 1.1 2.6 7.2 -1.0 -1.3 0.3 -0.6 -0.9 1.1 -2.3 -1.6 -2.7 -1.7 -2.3 -2.2 -0.3 -1.7 -1.6 -1.6
Chronotype (morning person) 0.6 1.3 4.1 1.0 1.7 1.4 -1.2 0.3 1.3 -1.0 0.6 -0.3 1.3 -2.0 -1.0 1.6 -1.3 -0.5 -0.1
Hair Pigment 0.0 0.5 2.9 -0.6 -0.7 -0.1 0.3 -1.0 -0.3 -0.2 -0.3 -0.6 -0.6 -0.4 0.2 -0.8 -1.7 -0.2 -0.9
Tanning 0.1 1.4 6.5 1.4 1.3 -1.4 0.6 -0.3 -0.3 1.2 0.6 1.3 0.4 1.2 1.3 0.0 1.0 1.3 2.6
Hand grip strength (left) 1.3 3.5 12.5 -0.7 -0.5 -1.6 0.3 -0.7 -1.7 2.1 -0.2 2.2 1.4 3.0 2.4 -0.2 3.5 2.5 2.0
Number of treatments/medications taken 0.6 1.1 4.2 -0.5 -0.8 0.6 -0.3 -0.5 0.7 -1.1 -1.3 -1.2 -1.9 -1.3 -1.0 0.5 -0.9 -0.7 -2.1
Average weekly spirits intake 0.5 0.6 2.1 0.3 -0.3 0.9 0.2 0.2 1.3 -0.7 -1.5 0.2 -0.1 -1.2 -1.1 0.6 -0.2 -0.7 -0.6
Sensitivity / hurt feelings 1.8 3.1 6.4 -2.3 -1.9 -1.5 1.4 -2.4 -0.9 -2.3 -1.1 -1.4 -0.8 -2.2 -2.5 -1.7 -1.8 -1.6 -1.5
Frequency of depressed mood in last 2 weeks 0.4 0.6 3.3 -1.4 -1.0 -0.1 0.4 -1.8 0.0 -0.3 -0.1 -0.2 -0.8 -0.9 -0.6 -0.1 -1.1 0.2 -0.3
Hearing difficulty/problems: Yes 0.4 0.6 4.6 0.7 0.3 1.2 -0.6 2.1 0.4 0.3 0.2 -0.2 0.7 0.5 0.2 1.3 0.4 -0.3 -0.3
Relative age of first facial hair 0.7 1.4 4.0 1.8 1.4 1.0 -2.0 1.8 0.3 0.0 2.0 -0.4 1.4 -0.7 -0.5 0.0 0.5 -1.3 0.3
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 3.7 -0.3 -0.8 0.3 -0.5 0.3 1.1 -0.1 -1.9 0.6 -0.2 0.3 0.9 1.9 -1.1 1.9 0.3
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.9 0.1 -0.8 -0.7 0.3 0.0 -1.3 -0.1 -1.4 -0.4 0.4 -0.1 -0.5 -0.5 0.1 -0.0 -0.7
Ever had hysterectomy (womb removed) 3.0 3.3 6.8 -2.5 -2.6 -1.2 2.2 -2.6 -0.2 -1.1 -2.4 -0.5 -2.0 -1.7 -1.6 -1.5 -2.3 0.1 -1.9
Systolic blood pressure, automated reading 1.7 4.8 13.9 2.8 3.2 3.0 -3.7 2.3 2.5 -1.5 1.2 -2.3 -0.6 -1.8 -1.6 1.9 -0.7 -2.3 -0.3
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 4.5 -1.0 -0.5 -0.3 -1.1 -0.1 -1.0 -0.1 1.0 0.0 0.4 0.1 -0.5 -1.1 -0.3 -1.8 -2.1
Angina 1.3 1.7 6.4 1.5 0.5 1.4 -1.6 1.2 2.5 -0.8 -0.5 -1.3 0.5 -1.5 -1.7 0.5 -0.6 -1.7 -0.8
Medication for hormone replacement therapy 1.0 1.1 4.1 0.4 0.2 0.5 -0.5 0.7 -0.5 1.4 -0.4 0.9 0.9 2.0 1.5 1.1 1.2 1.3 1.5
Vitamin and mineral supplements 0.2 0.3 0.8 0.1 0.1 0.6 -0.9 0.6 0.6 -0.6 -0.8 -0.8 0.1 -0.4 -0.6 0.1 -0.6 -0.3 -0.4
Supplements: Zinc 0.8 0.8 2.5 -1.0 -0.9 -0.7 -0.3 -1.4 -1.5 0.4 0.7 0.1 -0.5 0.2 -0.4 -1.4 0.9 -0.7 -1.6
Medication: Co-codamol 0.3 0.4 1.2 -0.6 -0.7 -0.0 -0.0 -0.1 0.4 -1.0 -1.1 0.4 -0.9 -0.6 -0.3 0.4 -1.1 0.2 0.1
Medication: Metformin 0.5 0.6 2.3 -1.5 -1.5 -1.1 0.7 -1.1 -0.3 -0.5 0.1 0.7 -0.4 0.1 0.2 -0.9 -0.8 -0.1 -0.6
Diabetes (father) 0.9 1.1 2.8 -1.0 -1.2 -1.4 0.4 0.5 -1.3 0.1 -1.4 -1.2 -1.4 0.2 -1.4 -1.7 0.7 -0.3 -0.4
Diabetes (mother) 0.2 0.2 1.1 -0.4 -0.5 -0.5 0.3 -1.1 -0.9 -0.3 -0.5 -0.3 -0.1 -0.0 0.3 -0.2 0.4 -0.5 -0.4
Severe depression (siblings) 0.5 0.5 2.4 0.6 0.6 1.5 -0.6 0.2 1.5 -0.4 0.5 0.1 0.4 -0.3 0.5 1.4 -0.2 0.1 0.0
Pack years adult smoking proportion 2.1 3.2 9.7 -1.0 -2.1 -3.1 0.6 -1.4 -2.1 -1.1 -3.0 -1.4 -1.7 -1.4 -1.8 -2.6 -1.3 0.1 -1.0
Impedance of leg (right) 1.0 4.7 16.6 4.1 3.1 1.0 -1.4 3.9 -0.1 2.6 3.4 -0.5 2.0 1.0 0.2 1.1 1.7 -0.4 1.8
Leg fat-free mass (left) 0.8 4.0 12.4 -3.2 -1.7 -1.3 -0.0 -3.5 -0.8 -2.9 0.1 -1.5 -3.5 -1.5 -0.5 -1.3 -1.8 -0.2 -2.5
Trunk fat percentage 0.7 2.9 13.7 0.9 1.2 -1.1 -1.3 0.2 -1.5 -1.7 3.7 -1.7 -0.8 -1.3 -0.9 -1.4 -1.4 -2.8 -2.3
Hand grip strength (right) 0.3 0.7 2.1 -1.1 -0.5 -1.1 -0.6 -1.5 -1.0 0.2 -0.4 0.3 -0.4 0.8 0.7 -1.0 1.3 0.6 0.5
Townsend deprivation index at recruitment 0.3 0.4 1.7 -0.3 0.4 -0.8 -0.6 -0.5 -1.3 0.8 0.4 -0.6 0.6 0.3 -0.1 -0.9 -0.0 -0.3 -0.9
Current tobacco smoking 1.5 2.5 6.2 0.2 -0.2 -1.3 -1.3 -0.9 -1.6 -1.7 0.3 -1.9 0.8 -2.2 -2.5 -2.3 -1.2 -2.1 -2.0
Average weekly fortified wine intake 2.1 2.5 10.9 1.0 1.1 3.3 -1.4 2.3 2.9 0.6 0.9 1.1 0.0 0.6 1.0 2.6 -0.1 0.6 -0.3
Maternal smoking around birth 0.6 0.9 3.9 2.0 1.6 -0.1 -0.2 1.3 0.1 0.8 0.7 0.1 0.3 0.8 0.8 0.6 0.6 0.3 1.8
Fed-up feelings 0.9 1.6 5.8 -2.4 -2.0 -0.1 0.4 -1.9 -0.1 -0.7 -1.3 -0.2 -0.8 -1.6 -1.1 -0.2 -1.8 -0.2 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 4.9 0.3 0.4 0.7 0.2 -0.2 0.4 2.2 0.4 0.7 1.8 1.1 0.9 1.1 0.8 1.2 0.8
Relative age voice broke 0.5 0.8 1.9 1.2 1.1 1.2 -1.2 0.9 1.0 0.3 0.8 0.3 0.8 0.3 0.6 1.4 0.5 -0.2 1.2
Taking other prescription medications 0.6 0.9 5.0 -0.7 -0.6 0.7 -0.9 0.2 1.1 -0.7 -2.2 0.1 -1.9 -0.7 -0.6 1.0 0.0 0.5 -0.6
Age when periods started (menarche) 0.8 1.9 3.7 1.9 1.5 1.7 -1.8 1.5 0.5 0.3 1.7 -0.5 1.8 1.6 1.3 0.8 1.9 -0.8 0.7
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 3.4 0.3 -0.2 -0.7 0.2 -0.2 -0.4 -1.1 -0.6 -1.2 -1.3 -1.6 -1.1 -0.1 -1.9 -0.4 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 9.8 0.1 -0.8 -0.6 1.0 1.0 0.1 0.7 -3.1 1.8 1.4 1.5 1.1 1.2 0.6 1.1 2.1
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 3.3 0.2 0.3 0.6 0.3 0.5 0.2 0.4 1.8 1.2 1.0 0.1 0.6 0.5 -0.5 -0.4 0.0
Qualifications: CSEs or equivalent 0.8 1.1 5.7 -1.3 -1.2 1.0 0.6 -0.4 1.6 -1.0 -0.5 -0.2 -2.4 -1.1 -1.0 -0.0 -0.6 -0.0 -0.1
Serious illness, injury or assault to yourself 1.0 1.2 5.8 -2.2 -2.4 -0.2 -0.2 -0.8 -0.2 -0.4 -1.4 0.4 0.4 -0.0 -0.1 -1.0 -0.6 -0.2 -1.9
High blood pressure 1.0 2.8 7.7 0.7 1.4 1.6 -1.1 0.8 2.4 -2.8 -0.2 -2.1 -1.6 -2.6 -1.9 1.0 -1.7 -1.6 -1.1
Hayfever, allergic rhinitis or eczema 1.5 3.1 8.3 0.3 1.4 0.7 0.2 0.7 -0.0 2.3 1.5 2.9 0.7 2.3 2.5 2.1 1.7 2.1 2.8
Multivitamins +/- minerals 0.5 0.6 2.6 -0.9 -1.6 -1.2 0.8 -0.7 -1.1 0.3 -0.2 0.4 -0.4 1.0 0.7 -0.9 0.5 0.2 0.3
Stomach or abdominal pain in last month 1.3 1.6 3.4 -1.1 -0.7 1.1 -0.6 -0.3 1.3 -1.2 -1.8 -0.8 -1.6 -1.8 -1.8 0.1 -1.8 -0.8 -1.4
Supplements: Glucosamine 0.4 0.5 2.1 1.4 1.0 -0.7 1.2 0.2 -0.5 -0.1 1.2 -0.3 1.0 -0.2 -0.1 -0.0 -0.3 -0.4 0.6
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 3.0 -1.2 -1.2 -1.3 0.5 -1.6 -0.9 1.2 -1.0 1.5 0.3 1.3 1.7 -0.3 -0.4 1.4 0.2
Medication: Atenolol 0.4 0.5 2.6 -0.4 -0.1 0.4 -0.3 -0.4 1.6 -0.8 -0.8 -0.8 -0.8 -0.8 -0.6 0.4 -0.8 -0.0 -0.2
Medication: Levothyroxine sodium 0.6 1.1 6.6 -1.1 -0.7 0.4 -0.6 -1.2 0.4 0.2 -2.6 0.7 -0.9 0.8 1.0 0.5 0.9 1.7 -0.5
Sitting height 0.2 1.3 5.2 -1.3 0.2 -0.7 -1.6 -2.3 -1.1 -0.8 1.0 -1.8 -1.3 0.5 0.7 -0.9 1.1 0.4 -0.5
Chronic bronchitis/emphysema (father) 1.4 1.7 4.5 1.6 1.3 1.4 -1.1 1.1 1.0 1.3 0.3 0.7 1.9 1.1 0.9 2.1 1.9 0.8 0.9
High blood pressure (mother) 1.2 1.6 4.9 -1.2 -0.6 0.4 -1.0 -0.8 0.7 -2.2 -1.8 -0.1 -1.2 -1.6 -1.3 -0.6 -1.1 -1.7 -1.8
Body mass index (BMI) 1.0 4.3 8.6 -2.1 -1.5 -2.2 0.5 -2.6 -1.5 -2.9 0.6 -0.6 -2.6 -2.2 -1.5 -2.2 -2.9 -2.1 -2.9
Impedance of leg (left) 0.9 4.1 14.0 3.7 2.7 0.9 -0.9 3.6 -0.1 2.6 3.0 -0.6 2.2 1.3 0.2 0.6 2.0 -0.6 1.7
Leg predicted mass (left) 0.7 3.8 12.3 -3.1 -1.7 -1.3 0.1 -3.5 -0.8 -2.8 0.2 -1.3 -3.3 -1.5 -0.4 -1.3 -1.8 -0.2 -2.4
Trunk fat mass 0.7 3.1 11.5 -0.1 0.6 -1.4 -1.2 -0.8 -1.5 -2.1 3.4 -1.8 -1.9 -1.3 -0.8 -1.6 -1.6 -2.4 -2.5
Waist circumference 1.0 3.6 10.4 -1.2 -0.7 0.1 -1.2 -0.6 -0.0 -3.2 0.5 -2.2 -2.9 -2.1 -1.9 -1.2 -2.5 -2.3 -3.1
Number of incorrect matches in round 1.4 2.3 13.3 -1.8 -1.7 0.1 0.2 -0.9 1.5 -1.6 0.2 0.1 -3.6 -1.8 -1.2 -0.0 -2.4 0.0 -1.2
Past tobacco smoking 1.5 2.8 8.6 -2.9 -1.5 -1.6 1.0 -2.8 -1.6 -1.8 -2.2 -1.3 -1.5 -0.9 -1.5 -1.5 -1.5 -0.5 -0.7
Alcohol usually taken with meals 1.8 2.9 8.7 -2.9 -2.5 -0.7 1.3 -1.4 -0.5 -2.2 -0.4 -1.1 -2.0 -1.4 -1.6 -2.3 -1.9 -0.8 -1.6
Nervous feelings 0.6 1.2 2.5 -0.9 -1.2 0.9 -0.6 -0.8 1.6 -1.2 -0.6 -1.4 0.2 -1.3 -1.1 -0.1 -1.4 -1.6 -1.1
Frequency of tenseness / restlessness in last 2 weeks 1.1 1.7 8.0 -2.5 -1.9 -0.7 1.9 -2.8 -0.3 0.4 -0.9 1.0 0.0 -0.1 0.1 -0.3 -1.4 0.7 0.1
Hearing difficulty/problems with background noise 1.6 2.5 8.7 2.4 2.8 2.2 -1.2 3.0 2.0 0.3 0.7 -0.6 0.9 0.2 0.2 2.0 0.8 -1.1 0.4
Hair/balding pattern: Pattern 2 0.5 0.6 1.8 -0.1 0.3 -1.1 1.3 -1.1 -0.8 -0.0 -0.7 -0.2 -1.2 -0.7 -0.1 -1.2 -0.8 0.3 0.1
Had menopause 0.3 0.4 1.8 1.3 0.4 0.4 0.2 0.4 0.4 0.6 -0.4 -0.7 0.9 0.1 0.2 0.8 -0.1 0.8 0.2
Had other major operations 2.0 2.4 7.2 -0.4 -1.0 -0.1 -0.3 -0.2 0.0 -1.9 -0.7 -2.1 -1.5 -2.6 -2.7 -1.9 -1.5 -1.3 -2.3
Forced vital capacity (FVC) 1.2 4.5 10.0 -2.2 -0.4 -1.5 -1.0 -2.2 -2.3 -2.4 2.8 -2.1 -0.5 -2.3 -2.3 -2.9 -0.7 -2.5 -3.2
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 5.1 0.1 -0.6 -0.3 1.2 1.0 0.3 1.1 -2.0 2.1 1.6 1.5 1.4 1.4 0.1 1.1 2.3
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 3.5 -1.1 -0.5 0.4 -0.3 -1.8 0.8 -1.1 1.8 -0.5 0.4 -1.9 -1.4 -0.8 -1.2 -1.6 -1.7
Qualifications: None of the above 0.8 1.7 5.9 0.0 -0.4 0.1 1.5 -0.3 1.4 1.9 -1.2 1.8 -0.5 0.8 1.5 1.8 -0.1 2.4 1.2
Financial difficulties in last 2 years 2.6 3.4 13.0 -3.6 -2.9 -1.9 2.5 -2.8 -2.3 -0.8 -0.7 0.2 -1.0 -0.2 -0.9 -2.5 -1.1 -0.2 -0.8
Mouth/teeth dental problems 0.6 1.0 7.3 0.7 0.4 -0.2 0.0 -0.8 0.2 1.0 -0.8 0.3 2.7 0.4 0.6 0.1 1.0 1.1 1.5
Heart attack 0.4 0.5 2.9 -0.3 -1.1 0.4 -0.2 -0.8 1.7 -0.1 0.5 0.7 -0.6 -0.6 0.4 0.6 -1.0 0.6 -0.2
Allergy 1.1 2.4 9.1 0.8 -0.2 -0.2 -0.3 0.1 0.3 -2.1 -0.9 -3.0 0.1 -2.3 -2.3 -1.6 -1.6 -2.0 -2.1
Pain all over the body in last month 1.9 2.0 7.6 -2.8 -2.1 -0.9 1.7 -2.2 -0.8 -0.7 -1.3 -0.0 -1.9 -0.2 -0.4 -1.8 -0.4 -0.1 -1.3
Diabetes (self-reported) 0.5 0.7 3.3 -1.5 -1.1 -0.8 0.7 -1.1 -0.1 -0.5 -1.8 0.6 -0.5 0.4 0.7 -0.5 -0.7 0.5 -0.2
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.5 0.6 0.4 0.3 0.0 0.4 0.1 1.1 0.7 1.5 -0.3 1.0 1.2 1.0 0.4 1.5 1.6
Medication: Ramipril 1.8 2.3 6.9 1.3 1.2 0.6 -1.1 1.2 1.4 -2.6 0.4 -1.7 -1.4 -2.2 -2.1 -0.2 -0.5 -2.2 -1.5
Medication: Simvastatin 1.3 1.8 6.2 1.7 1.2 2.5 -1.9 2.4 2.3 -0.5 -0.3 -0.8 -0.3 -0.4 -0.1 1.4 0.9 -0.6 -0.3
Fluid intelligence score 1.5 3.1 12.7 1.5 1.5 0.1 -1.0 0.4 -1.2 -1.5 3.6 -3.1 0.1 -0.9 -1.5 -2.0 0.7 -2.7 -1.7
Illnesses of siblings 0.7 1.0 2.9 -0.4 -0.6 -0.3 1.3 -0.7 0.2 0.7 -1.6 1.3 1.2 0.8 0.7 0.2 1.7 1.5 1.0
Neuroticism score 1.3 2.7 5.7 -1.7 -1.5 -0.1 -0.3 -1.7 0.6 -2.0 -1.6 -2.3 -0.8 -2.4 -2.4 -0.6 -1.9 -1.8 -1.8
Weight 0.8 4.0 11.6 -1.8 -0.7 -1.4 -0.9 -2.5 -1.2 -3.0 1.9 -1.8 -3.4 -1.8 -0.9 -1.7 -2.0 -1.7 -2.9
Impedance of arm (right) 1.1 4.9 17.5 4.2 3.3 0.8 -1.8 3.4 -0.7 1.7 3.5 -1.8 2.9 0.7 -0.5 0.5 2.2 -1.2 1.0
Arm fat percentage (right) 0.8 3.2 7.4 -0.1 0.2 -1.7 -0.4 -1.0 -1.8 -2.1 2.7 -1.2 -1.5 -2.0 -1.5 -1.8 -2.3 -2.7 -2.7
Trunk fat-free mass 0.6 3.6 18.2 -3.4 -1.7 -0.3 -0.4 -3.3 0.3 -2.5 -0.1 -0.9 -4.3 -1.1 0.0 -0.6 -1.2 0.7 -1.6
Hip circumference 1.1 4.7 9.7 -1.5 -1.0 -2.9 0.0 -2.9 -2.4 -2.5 2.3 -1.3 -1.8 -1.9 -1.5 -3.1 -1.7 -2.3 -3.1
Time employed in main current job 0.3 0.3 1.3 -0.3 -1.2 0.9 0.0 0.2 0.6 -0.3 0.6 0.1 -0.3 -0.4 0.0 0.5 -1.0 -0.4 -0.8
Alcohol intake versus 10 years previously 1.4 2.1 6.1 -1.7 -1.6 0.7 -0.2 -1.6 -0.1 -1.5 -0.5 -1.6 -2.5 -1.7 -1.2 -0.8 -2.1 -0.9 -2.1
Father’s age at death 0.8 1.1 3.5 0.7 0.3 0.1 -1.9 1.6 -0.9 0.0 -0.8 -1.5 -0.7 0.1 -1.3 -1.1 1.7 -0.3 -0.6
Worrier / anxious feelings 0.7 1.4 4.6 -0.6 -0.7 -0.3 0.2 -1.9 0.2 -1.5 -0.0 -1.2 -0.9 -2.1 -1.7 -0.4 -1.7 -1.3 -0.8
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.6 5.3 -1.0 -0.2 -1.4 0.6 -2.3 -1.6 -0.7 0.4 -1.3 0.6 -1.2 -1.7 -1.6 -0.1 -1.6 -1.5
Falls in the last year 1.3 1.8 4.5 -1.5 -1.5 -2.1 1.3 -1.0 -1.3 -0.8 -0.9 -0.6 -2.1 -1.1 -1.6 -2.1 -0.2 0.1 -1.0
Hair/balding pattern: Pattern 3 0.8 1.1 7.2 0.3 1.3 1.7 -0.9 -0.2 2.7 -1.0 0.2 -0.1 -0.2 -0.6 0.3 1.9 0.1 -0.2 0.5
Number of live births 0.7 1.0 2.9 -0.6 -0.4 -0.6 0.1 -1.7 -0.5 -1.4 0.4 -1.7 -1.6 -0.6 -0.8 -1.3 -0.7 -0.8 -1.0
Forced expiratory volume in 1-second (FEV1) 1.2 4.2 8.1 -2.5 -0.8 -1.4 -1.1 -2.5 -2.0 -2.3 2.8 -2.0 -1.3 -2.1 -2.1 -2.5 -0.7 -2.1 -2.7
Pulse rate 0.3 0.5 1.7 -0.4 -0.8 0.9 -0.1 1.3 0.7 0.6 1.1 -0.1 0.3 1.1 0.4 0.8 0.8 0.7 0.1
Happiness 1.3 1.6 6.3 -1.2 -1.0 1.8 0.4 0.0 1.9 -0.9 -1.1 -0.0 -0.7 -1.8 -1.4 0.7 -2.5 -0.5 -0.7
Noisy workplace 1.9 2.3 6.6 2.5 2.6 1.8 -0.5 2.4 1.3 1.1 0.0 0.9 2.0 0.4 0.9 2.4 0.1 0.3 0.7
Qualifications: A levels/AS levels or equivalent 0.4 1.0 2.9 0.5 0.5 -0.9 -1.7 -0.3 -1.4 0.2 1.4 -1.5 0.5 0.0 -0.6 -1.5 -0.0 -1.2 -0.8
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 3.5 0.3 0.8 -0.4 -0.4 -0.7 -0.5 1.1 -0.8 0.3 1.9 0.7 0.8 -0.5 1.4 -0.3 0.4
Mouth/teeth dental problems: Dentures 0.1 0.1 0.6 -0.2 -0.4 -0.8 -0.0 0.0 -0.7 -0.1 0.2 0.1 -0.4 0.4 0.4 0.3 -0.4 0.4 -0.2
Asthma 0.3 0.6 2.0 -1.4 -0.7 -0.6 0.2 -1.1 -0.8 -1.2 -0.5 -0.5 -1.4 -0.2 -0.6 -0.6 -0.2 -0.2 -0.8
Medication: Ibuprofen (e.g. Nurofen) 3.3 4.2 19.7 -1.7 -1.9 -4.0 2.4 -1.5 -4.4 0.3 1.5 -0.4 -0.9 0.0 -1.5 -3.0 -0.6 -1.2 -1.0
Medication: Cholesterol lowering 2.2 3.4 11.3 2.9 1.8 2.6 -2.7 3.4 2.8 -0.1 0.1 -0.7 0.5 0.1 0.1 1.9 2.2 -0.4 0.0
Depression (self-reported) 0.5 0.6 2.0 -0.8 -0.8 -1.0 -0.4 -1.0 -1.1 0.0 -1.4 0.2 0.9 -0.3 -0.6 -0.8 -0.2 0.0 -0.3
Medication: Lansoprazole 1.8 2.1 7.2 1.2 1.1 2.7 -2.0 1.3 2.6 -0.5 -1.7 -0.4 0.1 -1.0 -0.3 2.3 -0.9 -0.3 -0.5
Prospective memory result 0.8 1.0 5.3 1.3 1.1 0.7 -2.3 1.1 0.5 -0.4 -0.8 -0.2 -0.1 -1.3 -1.1 0.5 -0.2 -1.4 -0.8
Lung cancer (father) 0.2 0.2 0.5 0.5 0.3 0.5 -0.2 -0.0 0.6 0.1 0.7 0.1 0.3 -0.3 -0.2 0.3 -0.7 -0.6 -0.5
Illnesses of mother 0.4 0.5 2.0 0.2 0.5 -0.4 0.0 0.4 -1.1 1.0 -0.9 -0.4 0.9 0.8 0.1 0.2 0.1 1.4 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 1.4 4.5 11.6 -2.4 -0.9 -1.5 -1.3 -2.2 -2.2 -2.0 3.4 -2.0 -1.6 -2.0 -2.2 -2.8 -1.1 -2.3 -2.7
Pulse wave Arterial Stiffness index 1.4 1.6 8.4 0.1 0.0 2.0 -0.5 1.5 1.9 0.5 -1.5 1.2 0.6 0.6 1.1 2.9 0.4 1.0 0.5
Impedance of arm (left) 1.0 4.7 17.6 4.2 3.1 1.1 -2.1 3.6 -0.3 1.4 2.6 -1.9 3.0 0.7 -0.4 0.8 2.2 -1.1 0.9
Arm fat mass (right) 0.9 3.7 9.4 -1.4 -0.5 -1.5 -0.6 -1.8 -1.5 -2.7 2.0 -1.3 -2.5 -1.9 -1.3 -1.9 -2.3 -2.3 -3.1
Trunk predicted mass 0.6 3.5 17.1 -3.4 -1.7 -0.3 -0.4 -3.3 0.2 -2.5 -0.1 -0.9 -4.1 -1.1 -0.0 -0.7 -1.2 0.6 -1.7
Standing height 0.3 2.9 11.6 0.4 1.7 1.6 -3.4 -0.0 0.6 -1.0 3.0 -2.9 -2.2 0.4 0.9 0.8 1.8 0.4 -0.5
Length of working week for main job 0.6 0.6 1.7 -1.3 -0.8 -0.9 1.0 -1.0 -0.1 0.0 -0.9 0.2 -1.2 0.9 0.7 0.1 0.5 0.8 0.5
Exposure to tobacco smoke at home 2.5 2.8 8.6 -1.5 -2.4 -0.6 1.8 -1.6 0.1 -1.3 0.0 -0.3 -1.3 -2.2 -1.9 -1.4 -2.9 -1.3 -2.6
Breastfed as a baby 0.8 0.9 2.1 0.7 0.8 0.6 -1.5 1.4 -0.2 0.8 -0.1 0.2 0.1 1.4 1.2 0.5 1.4 0.9 1.5
Tense / ‘highly strung’ 0.9 1.6 4.0 -1.4 -1.5 1.2 -0.4 -0.9 1.2 -1.1 -0.8 -0.8 -0.9 -2.0 -1.8 0.0 -1.6 -1.4 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 5.6 -0.7 -0.8 0.3 -0.8 -0.5 0.1 -2.1 0.0 -2.1 -1.5 -2.1 -2.0 -0.3 -2.4 -1.2 -2.0
Hair/balding pattern: Pattern 4 0.9 2.2 7.0 0.6 0.1 -1.4 1.1 0.5 -1.8 2.3 1.2 1.3 2.2 2.6 1.6 0.7 1.5 1.2 1.5
Birth weight of first child 2.2 4.1 10.3 -0.6 0.3 -1.5 -1.5 -1.5 -1.4 -2.7 0.7 -2.3 -1.4 -2.8 -2.6 -2.7 -1.5 -3.2 -2.5
Peak expiratory flow (PEF) 0.3 0.7 5.2 -0.1 1.1 0.1 -1.6 -0.3 -0.6 0.1 2.3 0.1 0.4 0.5 1.0 0.4 0.3 0.3 0.5
Pulse wave reflection index 1.1 1.4 14.3 -0.8 -1.4 0.6 0.8 0.5 0.5 -0.0 -3.8 1.0 0.4 -0.0 -0.2 1.1 0.4 1.0 -0.2
Ever highly irritable/argumentative for 2 days 1.1 1.3 4.4 -0.9 -0.8 -1.0 2.1 -1.5 -0.3 0.5 -1.3 0.5 1.1 0.4 0.7 0.7 -1.7 1.2 1.6
Loud music exposure frequency 0.5 0.5 1.4 -0.3 -0.0 -0.6 0.9 -0.9 -0.2 0.5 0.7 0.7 0.4 0.6 1.1 -0.0 -0.5 1.2 1.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 4.1 -0.1 0.2 0.2 -1.7 -0.2 -1.0 -1.4 0.9 -2.0 -0.5 -0.8 -1.0 -1.1 -0.4 -1.5 -0.8
Mouth/teeth dental problems: Bleeding gums 3.2 4.1 12.9 -3.3 -3.0 -0.4 2.2 -1.6 0.0 -2.0 -0.4 -0.4 -3.6 -1.8 -1.7 -1.4 -3.0 -0.8 -1.9
Blood clot in the leg (DVT) 0.7 1.0 4.2 -0.5 -0.9 -0.9 -0.6 -0.5 -0.8 1.8 1.0 2.1 0.6 0.9 0.6 -0.2 0.8 1.3 0.4
Medication: Paracetamol 0.8 1.3 3.0 -0.7 -0.5 -1.0 0.7 -0.9 -1.4 -0.3 1.6 -0.7 0.7 -0.7 -0.8 -1.5 -1.7 -1.5 -1.6
Headache pain in last month 1.3 2.2 6.2 -2.0 -1.5 -1.6 1.0 -2.5 -1.9 -0.3 -0.7 -1.2 -1.1 -1.1 -1.5 -2.3 -1.1 -0.8 -1.5
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 4.5 -1.5 -1.1 -1.8 1.9 -1.9 -2.1 1.2 -0.4 1.3 0.9 1.0 0.7 -1.2 -0.5 1.1 0.9
Glaucoma (self-reported) 2.0 2.4 7.6 2.4 2.8 2.3 -1.7 1.9 2.5 -0.1 1.1 -0.4 0.0 -0.3 0.6 2.0 -0.3 -0.6 0.0
Gout (self-reported) 0.9 1.3 7.1 2.3 1.4 1.2 -0.1 2.7 1.0 0.6 0.4 -0.1 0.0 0.5 0.3 1.4 -0.1 0.8 0.7
Hypothyroidism/myxoedema (self-reported) 0.4 0.9 4.1 0.2 0.1 0.2 -0.4 -0.5 -0.2 1.0 -1.9 0.8 0.2 0.8 0.9 0.4 1.6 2.0 -0.2
Medication: Amlodipine 2.5 3.5 8.7 -0.4 -0.5 0.2 -2.1 0.2 0.1 -2.6 -1.4 -1.9 -2.7 -2.7 -2.5 -1.0 -3.0 -1.7 -2.3
Medication: Ventolin 100micrograms inhaler 0.5 0.7 1.8 -0.7 0.1 -0.3 1.0 -0.5 -0.0 -1.3 -1.2 -0.2 -1.1 -1.0 -0.7 -0.2 -1.3 -1.0 -0.6
Birth weight 0.8 1.8 5.2 1.0 1.4 -0.7 -1.0 -0.5 -1.2 1.8 1.4 0.8 1.2 1.3 1.0 0.6 2.3 1.8 1.9
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.1 0.8 -1.0 0.3 -0.4 1.3 0.7 1.3 -0.8 0.3 -0.0 0.6 -0.2 0.3 1.5 1.4 1.2
High blood pressure (siblings) 0.4 0.6 1.8 0.3 0.0 0.5 -0.5 1.3 0.8 -0.6 0.1 -0.8 -1.4 -0.5 -0.6 0.1 -1.2 -0.6 -1.1
Forced vital capacity (FVC), Best measure 1.3 4.8 10.8 -2.1 -0.2 -1.6 -1.4 -2.0 -2.4 -2.1 3.2 -2.1 -1.0 -2.0 -2.3 -3.3 -1.0 -2.8 -3.2
Body fat percentage 0.8 3.1 11.4 0.5 0.7 -1.7 -0.6 -0.3 -1.9 -1.7 3.4 -1.4 -1.2 -1.6 -1.2 -1.8 -1.9 -2.7 -2.4
Leg fat percentage (right) 0.6 2.1 5.3 0.3 0.2 -1.8 -0.2 -0.3 -1.7 -1.2 2.3 -0.7 -1.3 -1.5 -1.2 -1.5 -1.9 -1.9 -2.0
Arm fat-free mass (right) 0.8 4.1 18.0 -3.6 -2.1 -1.0 0.0 -3.5 -0.3 -2.6 -0.2 -1.0 -4.2 -1.1 -0.1 -1.3 -1.5 0.3 -2.0
Exposure to tobacco smoke outside home 1.0 1.3 5.5 -1.5 -1.9 -1.1 2.2 -0.9 -0.7 -0.0 0.3 0.5 -2.3 -0.0 -0.3 -0.6 -0.6 0.9 -0.1
Comparative body size at age 10 0.3 0.9 3.6 -1.0 -0.2 -1.2 -0.5 -0.5 -1.1 -0.7 -0.5 -0.5 -1.9 -0.6 -0.8 -1.4 -0.9 -0.2 -1.4
Number of full brothers 0.4 0.5 2.5 -0.2 -0.2 -0.3 -0.3 -0.4 -0.2 -0.8 1.6 -0.4 -0.2 -0.8 -0.9 -0.7 -1.4 -0.9 -0.6
Worry too long after embarrassment 0.5 0.9 3.4 0.7 0.4 -0.3 -0.6 -0.2 0.6 -1.3 -0.2 -1.8 -0.4 -1.6 -1.5 -0.2 -0.7 -1.3 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 3.0 -1.7 -1.1 0.5 0.6 -1.1 0.9 -1.3 -0.3 -0.5 -1.1 -1.2 -1.2 -0.0 -1.1 -0.8 -1.6
Wheeze or whistling in the chest in last year 0.2 0.3 1.2 -0.1 -0.0 0.5 0.8 -1.1 0.6 0.4 -0.8 -0.1 0.0 0.1 0.4 1.0 0.3 0.8 0.6
Number of children fathered 0.7 0.8 3.8 -0.7 -1.9 -0.7 -0.2 0.3 0.2 -0.4 0.3 0.9 -1.4 0.8 1.1 -0.5 -0.3 1.2 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 2.2 0.4 0.4 0.4 0.2 1.2 0.5 -0.9 0.4 -0.8 -1.5 -0.2 -0.2 0.2 0.1 -0.2 0.2
Age at first live birth 1.0 1.9 7.1 1.0 0.8 0.9 -0.7 1.5 0.7 1.3 -0.3 0.8 2.6 1.8 1.3 0.7 2.7 0.9 1.2
Pulse wave peak to peak time 1.4 1.6 7.3 -0.1 0.2 -1.7 -0.0 -1.5 -1.6 -0.8 1.9 -1.6 -0.9 -0.8 -1.1 -2.7 -0.3 -1.1 -0.7
Health satisfaction 0.9 1.2 2.7 -0.8 -1.1 0.7 -1.1 0.1 0.7 -1.1 -1.1 -1.4 -1.2 -1.5 -1.4 -0.3 -1.1 -0.7 -1.6
Shortness of breath walking on level ground 0.9 1.1 3.0 1.0 0.8 -0.2 0.8 0.7 -0.1 1.2 -0.4 1.4 1.7 0.8 1.3 1.5 0.1 1.0 1.7
Qualifications: College or University degree 0.6 1.8 4.4 0.9 1.3 -1.3 -1.6 -0.6 -2.1 -1.0 1.9 -2.1 -0.4 -0.5 -1.3 -1.7 1.2 -1.4 -0.9
Eye problems/disorders: None of the above 0.8 0.9 3.1 -0.6 -1.2 -1.3 1.8 0.2 -1.1 0.7 -0.4 1.0 0.1 0.7 0.3 -0.4 0.6 1.6 1.0
Mouth/teeth dental problems: Loose teeth 1.1 1.4 3.9 1.1 1.9 1.5 -1.5 2.0 1.1 -1.2 -1.8 -0.7 -0.0 -0.5 -0.4 1.1 -0.3 -0.7 -0.3
Emphysema/chronic bronchitis 1.3 1.4 4.5 -0.0 -0.4 -0.8 1.2 -0.4 -0.0 2.1 -1.4 1.6 0.9 1.4 1.3 0.4 1.4 2.1 1.1
Medication for pain relief, constipation, heartburn 0.6 1.1 3.0 1.3 1.7 1.6 -1.7 1.5 1.5 -0.3 -1.2 -0.1 0.6 -0.2 -0.0 0.8 0.2 -0.2 0.7
Neck or shoulder pain in last month 1.4 2.0 5.8 -1.1 -1.0 -1.4 -0.0 -1.3 -1.2 -1.5 -0.1 -1.4 -2.2 -1.7 -1.7 -1.4 -2.4 -0.8 -1.2
Medication: Blood pressure 0.6 1.1 2.2 0.8 0.7 0.9 -0.6 0.7 1.4 -1.5 0.9 -1.5 -1.2 -1.3 -0.9 0.5 -0.5 -1.3 -1.0
Angina (self-reported) 1.1 1.5 5.8 1.3 0.4 1.3 -1.5 1.1 2.4 -0.6 -0.5 -1.1 0.6 -1.3 -1.5 0.5 -0.5 -1.7 -0.8
Migraine (self-reported) 2.1 2.6 7.7 0.0 -0.5 0.4 -0.7 -0.3 -0.0 -1.6 0.1 -2.8 -0.8 -2.3 -2.7 -1.6 -1.0 -2.5 -2.8
Medication: Ibuprofen 3.5 4.2 16.7 -2.3 -2.4 -3.9 2.5 -2.4 -4.1 0.4 0.6 -0.2 -1.1 -0.1 -1.2 -2.9 -1.0 -0.3 -0.9
Medication: Allopurinol 0.6 0.8 2.8 1.5 0.7 0.5 0.2 1.6 0.9 -0.3 1.7 -0.4 -1.0 0.1 0.2 0.8 -1.0 0.3 0.6
Medication: Omeprazole 0.5 0.6 2.3 -0.9 -0.8 -0.1 0.2 -1.5 0.5 0.3 -1.1 0.7 -0.9 -0.1 0.3 1.0 0.1 1.1 0.7
Medication: Seretide 50 evohaler 0.4 0.4 2.5 -1.2 -1.1 0.3 -0.0 -0.2 -0.3 -0.5 -1.6 0.5 0.4 0.3 -0.1 0.0 0.3 -0.3 -0.6
Mean time to correctly identify matches 0.2 0.4 1.1 1.0 0.3 0.9 -0.8 1.0 0.7 -0.0 -0.8 -0.3 0.5 -0.3 0.1 0.5 0.1 -0.5 -0.5
Heart disease (mother) 0.1 0.1 0.7 0.3 -0.2 -0.1 -0.1 0.2 0.4 -0.6 0.8 -0.1 -0.1 -0.2 -0.1 0.2 -0.1 -0.4 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 3.0 -0.4 -0.3 -0.6 1.4 -0.3 -0.5 0.4 -0.6 0.1 -1.3 0.1 -0.7 0.8 0.7 1.4 1.7
Whole body fat mass 0.9 3.6 8.6 -1.0 -0.3 -1.8 -0.6 -1.4 -1.8 -2.4 2.7 -1.5 -2.4 -1.7 -1.1 -2.1 -2.1 -2.2 -2.9
Leg fat mass (right) 0.8 3.2 7.6 -1.0 -0.4 -2.0 -0.1 -1.5 -1.8 -2.1 2.1 -1.1 -2.3 -1.8 -1.1 -2.0 -2.3 -1.9 -2.8
Arm predicted mass (right) 0.8 4.2 16.6 -3.5 -1.9 -1.0 -0.1 -3.5 -0.4 -2.8 -0.2 -1.1 -4.1 -1.3 -0.2 -1.4 -1.8 -0.1 -2.2
Pulse rate, automated reading 0.6 1.9 5.0 1.2 0.5 0.5 -1.7 1.5 0.5 -1.7 -0.1 -2.2 0.1 -1.6 -2.2 -0.4 -0.1 -2.1 -1.5
Alcohol intake frequency. 4.7 11.0 30.6 -5.5 -5.1 -1.9 2.6 -5.5 -1.5 -1.8 -4.0 -0.7 -2.4 -2.8 -2.9 -2.9 -3.4 -0.5 -3.8
Comparative height size at age 10 0.5 2.7 9.4 -1.8 -0.2 0.3 -1.5 -2.5 -0.1 -2.0 0.5 -3.1 -2.9 -1.5 -1.0 -0.9 -0.2 -0.5 -2.3
Number of full sisters 0.9 1.1 4.8 2.2 0.9 1.1 -1.3 1.6 1.0 0.9 -0.2 -0.2 1.1 -0.0 0.1 1.2 1.2 0.5 0.2
Suffer from ‘nerves’ 1.3 2.1 7.4 -2.3 -2.6 -0.8 0.6 -1.6 0.0 -1.2 -1.7 -1.8 -2.7 -0.4 -1.0 -0.7 -0.6 0.4 -0.7
Overall health rating 0.8 1.6 3.2 -1.7 -1.8 0.1 -0.1 -1.4 0.7 -1.4 -0.8 -1.2 -1.6 -1.5 -1.5 -0.2 -1.8 -0.7 -1.5
Chest pain or discomfort 0.5 0.7 2.5 0.3 -0.2 1.1 -0.9 0.9 1.4 0.6 -0.4 -0.1 -0.8 0.1 0.0 1.6 -0.2 1.2 1.0
Had major operations 0.6 0.7 3.0 0.3 -0.3 0.3 -1.4 0.0 -0.2 1.1 0.2 0.2 1.1 1.6 1.7 0.6 0.7 0.8 0.0
Age at last live birth 0.3 0.4 2.8 0.5 0.8 0.4 -0.3 0.1 0.0 0.3 0.9 -0.1 1.7 0.6 0.6 -0.0 1.2 0.0 -0.3
Family relationship satisfaction 1.3 1.6 6.4 -1.8 -1.2 0.9 0.9 -1.6 1.9 -0.8 -0.3 0.8 -1.9 -0.9 0.1 0.4 -2.5 0.2 0.2
Leg pain on walking 0.9 1.1 4.2 -0.5 -0.9 1.0 -1.0 0.1 1.1 -1.6 -0.7 -0.3 -1.1 -1.5 -0.8 0.6 -2.0 0.2 -0.9
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.7 7.1 -2.7 -2.5 -1.3 0.9 -1.1 -1.5 -0.3 -0.8 -0.0 0.1 0.4 -0.3 -2.0 -1.4 -0.8 -1.1
Commuting to job workplace: Car/motor vehicle 0.5 0.5 2.9 -0.5 -0.8 -0.3 0.8 0.2 -0.1 -0.3 1.0 1.0 -1.7 -0.4 0.4 -0.4 -1.1 0.5 -0.1
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 2.8 1.7 1.7 1.3 -0.9 1.3 1.2 0.2 -0.2 0.2 -0.6 -0.0 0.5 1.5 -0.4 0.4 1.0
Medication: Aspirin 0.5 0.7 2.9 0.8 -0.1 0.9 -0.4 0.9 1.7 0.0 -0.7 -0.2 -1.2 -0.0 0.1 1.3 0.7 1.1 0.7
Supplements: Vitamin C 0.7 0.8 2.7 -0.6 -0.4 -0.5 1.4 -1.6 0.1 0.4 1.0 1.5 0.6 0.3 1.1 1.0 0.1 0.9 0.9
Knee pain experienced in last month 1.0 1.5 3.8 0.8 0.0 1.1 -1.6 0.6 1.3 -1.2 -0.2 -0.5 -1.8 -2.0 -1.4 0.3 -1.4 -1.4 -1.4
Hypertension (Self-reported) 1.1 3.1 8.0 0.8 1.7 1.7 -1.5 0.9 2.5 -2.8 0.0 -2.4 -1.8 -2.6 -2.0 0.8 -1.2 -1.7 -1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 3.2 -1.0 -1.1 -1.6 0.5 -1.8 -1.5 0.9 -0.4 0.6 -0.2 -0.1 -0.4 -0.7 -0.5 0.0 -0.2
Illnesses of father: Heart disease 0.7 1.0 3.0 -0.0 -0.9 -0.9 0.4 -0.3 -1.4 1.6 1.3 1.0 1.7 0.5 0.2 0.2 0.2 1.5 0.7
Illnesses of siblings: Diabetes 1.0 1.3 3.5 -1.0 -1.3 -1.3 -0.2 -0.5 -1.9 -0.9 -0.7 -1.5 -1.8 -0.0 -0.6 -1.6 -0.7 -0.8 -1.1
Smoking status: Previous 3.4 5.1 8.9 3.0 2.2 2.2 -0.1 3.0 2.4 2.8 1.8 2.6 2.0 1.8 2.6 2.8 1.9 1.4 1.9
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 4.0 -1.7 -0.6 -0.7 1.0 -2.0 -0.6 0.1 0.1 0.1 -0.1 0.3 0.3 -0.7 -0.1 0.4 0.3
Whole body fat-free mass 0.7 4.1 16.6 -3.4 -1.8 -0.8 -0.2 -3.6 -0.2 -2.8 -0.1 -1.2 -4.1 -1.4 -0.3 -1.1 -1.5 0.2 -2.1
Leg fat-free mass (right) 0.8 4.1 13.1 -3.4 -2.0 -1.2 0.2 -3.6 -0.7 -2.9 -0.4 -1.4 -3.3 -1.4 -0.5 -1.4 -1.5 -0.3 -2.5
Arm fat percentage (left) 0.8 3.1 7.3 -0.3 0.0 -1.9 -0.3 -1.0 -1.9 -2.2 2.4 -1.1 -1.3 -1.9 -1.4 -1.9 -2.2 -2.6 -2.7
Average weekly red wine intake 0.3 0.5 1.9 0.5 0.9 0.2 0.1 -0.3 -0.2 -1.4 -0.2 -0.7 0.7 -1.1 -0.9 -0.2 0.1 -1.3 -0.4
Handedness (chirality/laterality): Left-handed 1.2 1.5 4.9 -1.2 -2.1 -1.0 -0.5 -0.2 -0.8 -1.5 -0.5 -0.5 -0.4 -0.7 -1.3 -1.6 -1.4 -1.2 -2.2
Mood swings 1.4 2.5 6.6 -1.8 -1.6 -0.5 0.6 -2.2 -0.0 -1.3 -1.2 -1.6 -0.9 -2.6 -2.0 -1.1 -2.2 -0.9 -2.0
Loneliness, isolation 0.5 0.7 3.2 -1.5 -1.8 -0.6 0.2 -1.4 0.2 0.3 -0.0 0.1 -1.3 0.3 0.1 0.5 -0.2 1.0 0.5
Long-standing illness, disability or infirmity 0.3 0.4 1.7 -0.5 -0.9 0.5 -0.4 0.4 0.5 0.2 -1.3 0.3 0.7 0.0 0.3 1.3 -0.5 0.5 -0.9
Ever had bowel cancer screening 2.2 2.6 8.8 2.2 1.6 3.0 -2.0 2.4 2.5 0.9 0.8 -0.5 0.4 -0.2 -0.2 2.3 1.2 0.3 -0.3
Diabetes diagnosed by doctor 0.4 0.6 4.0 -1.3 -1.0 -0.1 -0.3 -0.8 0.3 -1.0 -2.0 -0.1 -0.7 0.2 0.2 -0.2 -0.8 -0.1 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.2 3.7 -1.8 -1.9 -1.2 1.7 -1.3 -0.7 -0.4 -1.5 0.2 -0.1 -0.6 -1.3 -0.9 -0.9 0.1 -0.5
Friendships satisfaction 0.9 1.1 3.2 -1.2 -0.8 1.3 -1.1 0.1 1.7 -1.3 -0.5 0.2 -1.8 -1.0 -0.7 0.3 -1.7 -0.4 -0.6
Qualifications: nursing, teaching 1.1 1.7 5.7 0.8 1.1 -0.3 -2.4 0.2 -1.2 -1.6 1.8 -1.7 0.6 -0.4 -0.8 -1.2 0.6 -2.0 -1.3
Commuting to job workplace: Walk 0.4 0.5 3.9 0.0 -0.0 -0.2 -0.9 0.3 0.6 -0.1 -0.2 -0.9 0.2 0.3 -0.3 0.0 2.0 1.1 0.4
Eye problems/disorders: Cataract 0.4 0.5 1.6 -0.6 0.3 0.4 -1.1 -1.3 -0.5 -0.7 0.9 -0.4 -0.4 -0.5 -0.1 -0.2 -0.7 -0.6 -0.9
Mouth/teeth dental problems: Mouth ulcers 1.7 2.7 6.2 -1.0 -0.4 -0.7 1.0 -0.0 -1.7 -1.1 2.5 -0.8 -2.5 -1.6 -2.4 -2.1 -0.2 -2.1 -2.5
Medication for cholesterol 0.7 1.0 9.1 0.9 1.2 -1.0 0.3 -0.1 -1.0 0.5 3.0 0.3 0.8 0.4 0.5 -0.5 -0.1 -0.8 0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.8 0.9 0.1 -0.8 -0.4 -0.7 -0.7 0.2 -0.3 -0.7 0.9 0.1 0.3 -0.3 -0.1 -0.1 -0.0
Back pain experienced in last month 1.3 1.9 7.4 -1.6 -1.1 -1.5 1.7 -2.7 -0.4 -1.3 0.5 -0.9 -1.3 -1.2 -0.7 -1.3 -1.6 -1.5 -0.8
Mineral and other dietary supplements 0.5 0.6 3.0 -1.6 -1.4 -0.2 0.6 -0.1 0.0 -0.1 -1.7 0.5 -0.9 0.1 -0.3 -0.1 -0.3 0.8 0.3
Breast cancer (self-reported) 1.0 1.2 3.1 0.1 -0.6 0.9 -0.8 0.6 1.5 -0.9 0.5 -1.0 -1.3 -1.8 -1.2 -0.1 -1.5 -0.9 -1.6
Asthma (self-reported) 0.3 0.7 2.3 -1.0 -0.5 -0.6 0.3 -1.2 -0.9 -1.3 -0.3 -0.9 -1.5 -0.3 -0.7 -0.7 -0.2 -0.5 -0.9
Osteoporosis (self-reported) 0.3 0.4 1.2 0.5 0.6 0.5 -0.3 0.8 0.5 -0.2 0.8 0.5 -1.1 -0.7 0.2 0.8 0.0 0.9 -0.0
Osteoarthritis (self-reported) 0.4 0.5 2.1 -0.1 -0.4 -1.4 0.4 -0.2 -1.4 0.8 0.3 0.1 0.7 1.0 0.1 -0.9 0.6 0.3 0.5
Medication: Aspirin 0.6 0.8 3.6 0.6 -0.2 1.1 -0.8 1.0 1.9 0.0 -0.8 0.0 -1.2 0.1 0.3 1.5 0.6 1.1 0.6
Medication: Gliclazide 1.3 1.5 4.9 0.5 0.5 1.2 0.1 0.9 1.3 1.1 -0.1 1.5 0.7 1.8 2.2 1.6 -0.1 1.6 1.6
Illnesses of father: None of the above (group 1) 0.4 0.5 1.5 -0.1 0.1 1.0 -1.0 0.2 1.1 -0.9 -0.5 -0.2 -0.4 -0.3 0.8 0.5 -1.2 -0.5 -1.0
Smoking status: Current 1.7 2.7 7.3 0.5 -0.1 -1.0 -1.4 -0.5 -1.3 -1.9 0.2 -2.3 0.6 -2.4 -2.7 -2.1 -1.4 -2.2 -2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 7.7 -0.4 0.2 0.2 -2.0 0.4 -0.3 -1.3 2.8 -1.5 -0.7 -2.0 -2.0 -1.0 -1.1 -2.5 -2.0
Whole body water mass 0.7 4.0 17.0 -3.5 -1.9 -0.8 -0.1 -3.6 -0.2 -2.8 -0.1 -1.2 -4.1 -1.3 -0.2 -1.1 -1.5 0.3 -2.0
Leg predicted mass (right) 0.8 4.1 12.5 -3.3 -1.9 -1.1 0.0 -3.5 -0.6 -3.0 -0.4 -1.6 -3.3 -1.4 -0.6 -1.4 -1.5 -0.3 -2.5
Arm fat mass (left) 0.9 3.8 9.2 -1.4 -0.5 -1.7 -0.6 -1.8 -1.6 -2.8 1.8 -1.4 -2.6 -2.0 -1.4 -2.0 -2.3 -2.3 -3.0
Number of self-reported non-cancer illnesses 0.5 0.9 5.3 -0.7 -1.5 -0.6 0.1 0.1 0.1 -0.8 -2.3 -0.2 -1.4 -0.7 -1.2 0.4 -0.6 0.3 -0.9
Average weekly champagne plus white wine intake 0.3 0.4 2.2 0.2 0.6 0.0 -1.1 0.6 -0.2 -0.1 1.5 -0.3 -1.3 -0.1 -0.7 0.0 0.5 -0.1 0.3
Miserableness 0.6 1.1 5.3 -0.0 0.6 0.5 -0.8 -0.1 0.5 -1.2 -0.6 -2.3 0.1 -1.7 -1.8 0.2 -1.0 -1.1 -1.0
Guilty feelings 0.6 0.9 2.9 1.1 1.1 0.3 0.1 -0.0 0.9 0.8 1.3 1.4 1.7 -0.1 0.8 1.7 -0.4 0.2 0.9
Wears glasses or contact lenses 0.7 0.9 3.8 0.1 0.5 1.5 -0.5 0.0 1.4 -0.4 -1.9 -0.6 -0.1 -0.3 0.5 1.6 -1.2 0.4 -0.1
Ever taken oral contraceptive pill 0.8 0.9 3.4 -1.8 -1.1 -0.3 0.5 -0.9 -0.6 -1.0 -1.5 -0.4 -1.0 -0.4 -1.1 -1.0 -0.8 -0.9 -0.1
Hearing aid user 0.6 0.7 3.3 0.6 0.4 1.4 0.1 0.9 1.0 0.7 0.5 1.1 0.4 -0.5 -0.1 1.8 -0.3 0.6 -0.1
Mother’s age at death 0.8 1.0 3.1 -1.3 -1.1 -1.1 1.8 -1.0 -1.4 0.5 1.1 1.3 0.9 0.5 0.4 -1.2 -0.2 0.2 -0.4
Financial situation satisfaction 1.2 1.4 3.8 -1.3 -1.2 -0.2 0.9 -1.1 -0.2 -1.6 0.4 -0.1 -0.2 -1.5 -1.1 -1.4 -2.0 -1.9 -1.4
Tinnitus: Yes, now most or all of the time 0.6 0.6 2.4 0.1 -0.8 -1.5 1.2 -0.3 -0.7 1.1 -0.9 0.6 1.0 0.1 -0.0 -0.9 -0.8 0.9 0.4
Commuting to job workplace: Public transport 0.3 0.4 1.4 -0.1 -0.1 1.1 -1.2 0.4 1.1 -0.1 0.7 -0.1 -0.3 -0.2 -0.6 0.6 0.5 -0.8 -0.2
Eye problems/disorders: Glaucoma 1.6 1.9 6.1 2.5 2.4 1.3 -1.2 1.4 1.8 -0.0 2.4 0.1 0.5 -0.6 0.4 1.2 -1.0 -1.1 -0.0
Medication: Blood pressure 1.2 2.3 6.7 0.3 0.6 1.7 -1.5 0.6 2.2 -1.9 -1.4 -1.8 -1.4 -2.6 -2.3 0.4 -0.7 -1.2 -1.2
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.1 0.1 -0.4 0.1 -0.1 0.8 0.3 1.3 0.8 1.3 1.4 0.8 0.7 0.7 0.3 1.5 0.6
Supplements: Fish oil (including cod liver oil) 0.5 0.7 2.5 1.6 1.6 0.0 -0.9 0.1 -0.1 0.4 1.6 -0.0 1.0 0.5 0.8 0.3 0.8 -0.4 0.3
High cholesterol (Self-reported) 0.7 1.2 6.6 1.3 -0.0 1.3 -0.2 1.9 2.6 0.1 -1.4 0.1 -0.8 -0.3 -0.0 1.2 1.0 0.6 0.2
Medication: Bendroflumethiazide 1.9 2.9 7.4 0.5 0.8 2.4 -1.7 0.9 2.3 -1.9 -0.3 -2.0 -0.8 -2.7 -2.0 1.2 -1.5 -1.9 -1.9
Medication: Paracetamol 1.0 1.5 3.9 -1.4 -1.0 -0.7 1.5 -1.4 -1.0 -0.6 0.9 -0.8 0.3 -1.1 -1.1 -1.5 -1.7 -1.2 -2.0
Medication: Lisinopril 0.4 0.5 1.8 0.4 -0.3 1.3 -0.7 1.1 1.3 -0.0 -0.4 -0.8 0.6 0.6 0.8 0.9 0.2 -0.0 0.2
Medication: Atorvastatin 0.8 0.9 3.5 -1.0 -1.9 -1.0 1.3 -1.5 0.6 -0.8 -1.1 0.7 -0.5 -0.9 -0.3 -0.4 -0.0 0.6 -1.0
Illnesses of father: High blood pressure 0.3 0.4 1.4 -0.7 -0.6 -0.4 0.4 -1.1 -0.0 -0.5 1.0 -0.1 -1.1 -0.2 -0.2 0.1 -1.2 -0.3 0.5
Alcohol drinker status: Never 1.2 1.4 4.2 -1.3 -1.0 -0.2 -0.9 -1.4 0.2 -1.2 -2.1 -1.4 -1.1 -1.3 -1.6 -0.8 -0.7 -0.5 -1.5
Ever smoked 0.7 1.3 4.0 2.0 0.7 1.2 -1.1 1.9 1.2 0.9 1.6 0.7 0.5 0.8 1.3 0.9 0.9 0.5 0.4
Basal metabolic rate 0.7 4.1 16.5 -3.1 -1.7 -1.0 -0.4 -3.3 -0.6 -2.9 0.4 -1.4 -4.1 -1.5 -0.5 -1.4 -1.6 -0.3 -2.4
Leg fat percentage (left) 0.6 2.1 4.7 0.0 -0.0 -1.9 0.0 -0.5 -1.7 -1.3 1.9 -0.8 -1.4 -1.4 -1.2 -1.8 -1.8 -2.1 -2.2
Arm fat-free mass (left) 0.8 4.1 18.7 -3.4 -1.9 -1.0 -0.0 -3.6 -0.4 -2.7 0.2 -1.0 -4.3 -1.3 -0.2 -1.3 -1.7 0.1 -2.0
Number of operations (self-reported) 1.2 1.8 4.8 -0.7 -1.4 0.5 -2.0 0.1 0.7 -0.9 -2.1 -2.2 -2.1 -1.0 -1.5 -0.6 -0.7 0.0 -1.5
Average weekly beer plus cider intake 1.3 2.0 5.8 2.1 2.4 2.0 -2.2 1.7 1.4 -0.3 -0.7 -1.0 1.1 -0.0 0.3 1.3 0.7 -1.6 0.1
Irritability 0.7 1.1 3.4 -1.8 -1.4 -0.1 0.6 -1.7 -0.1 -0.7 -0.7 -0.4 0.3 -1.5 -1.1 -0.5 -1.4 -1.2 -1.2
Risk taking 0.7 1.0 3.5 -0.5 0.2 -0.1 -0.1 -0.5 -0.3 1.0 -0.5 1.2 1.4 1.7 1.9 0.6 1.2 1.4 0.9
Ever had prostate specific antigen (PSA) test 2.5 2.9 11.4 0.6 0.6 2.8 -1.7 1.5 2.9 0.9 0.2 1.6 -0.1 1.1 2.0 3.4 0.3 1.5 1.2
Fractured/broken bones in last 5 years 0.4 0.6 2.3 -0.5 -0.1 0.1 0.4 -0.6 0.4 1.2 0.8 1.5 1.1 0.7 0.9 0.2 -0.1 0.6 0.8
Age started oral contraceptive pill 0.2 0.3 0.8 0.3 -0.8 0.0 -0.7 0.9 -0.4 -0.5 0.4 -0.7 0.3 -0.3 -0.6 -0.3 0.5 -0.3 -0.5
Diastolic blood pressure, automated reading 1.3 4.1 11.8 1.4 1.4 1.0 -3.1 1.3 0.2 -2.5 -0.4 -3.4 -1.1 -2.3 -3.4 -0.1 -1.3 -3.0 -1.7
Ever depressed for a whole week 0.7 0.8 2.9 -0.6 -0.7 -0.0 -0.0 -0.7 0.8 -1.3 1.7 -0.7 -1.2 -1.4 -1.0 -0.5 -0.7 -0.6 -1.0
Unable to work because of sickness or disability 0.9 1.1 4.3 -2.1 -1.9 0.1 0.8 -0.9 0.6 -1.3 -1.6 0.3 -0.6 -0.6 -0.5 -0.7 -0.9 -0.6 -1.1
Commuting to job workplace: Cycle 0.7 0.8 4.8 1.4 1.8 -0.2 -0.3 0.1 0.2 0.1 -0.7 -0.5 0.1 0.7 0.8 0.7 0.8 0.4 2.2
Myopia 1.5 2.1 6.4 1.8 2.5 2.1 -1.1 2.5 1.3 -1.0 0.3 -1.7 -0.3 -1.2 -0.9 1.8 -0.7 -0.7 -0.5
Vascular/heart problems diagnosed by doctor 0.8 2.3 6.6 -0.8 -1.1 -1.7 1.6 -0.9 -2.6 2.3 0.5 1.7 1.4 2.0 1.4 -1.3 1.2 1.2 0.9
Cholesterol lowering medication 1.3 2.0 8.6 -1.4 -2.3 0.6 0.7 -0.4 1.7 -1.4 -2.9 -0.3 -1.5 -1.5 -0.8 -0.0 -1.1 0.8 -1.4
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.1 -0.8 -0.8 -0.1 0.5 -1.4 0.1 1.0 -0.9 1.5 -0.6 0.6 0.9 1.1 0.3 1.5 1.1
Pain experienced in last month 0.7 1.1 3.4 0.8 0.9 0.1 -0.8 1.8 -0.2 0.8 1.3 1.0 1.3 1.3 1.0 0.4 1.8 0.9 0.7
Supplements: Calcium 0.8 0.9 4.0 1.8 2.0 1.0 -0.4 0.9 1.1 0.4 1.0 -0.3 0.3 0.3 0.8 1.1 0.1 -0.5 0.5
Basal cell carcinoma (self-reported) 0.6 0.7 3.5 -1.0 -0.3 -1.2 1.3 -0.5 -1.1 0.3 0.2 1.9 0.3 0.3 0.8 -0.6 -0.3 0.9 0.5
Heart attack/myocardial infarction (self-reported) 0.5 0.6 3.1 -0.6 -1.4 0.5 -0.3 -0.8 1.8 0.0 0.1 0.7 -0.6 -0.3 0.5 0.6 -0.9 0.8 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 5.9 -0.5 -0.8 -0.7 -0.5 -0.5 -0.9 1.9 0.9 2.4 0.7 1.0 1.0 0.0 0.5 1.4 0.5
Heart disease (siblings) 0.5 0.7 3.7 0.4 1.3 0.1 -1.3 0.1 -0.0 -0.6 1.9 0.1 -0.0 -0.7 -0.3 -0.1 -0.9 -1.2 -0.1
Alcohol drinker status: Previous 0.2 0.2 1.3 -0.1 0.3 0.3 0.1 0.3 -0.4 0.5 -0.7 -0.8 1.1 0.5 -0.2 -0.3 0.3 -0.4 -0.4
Pack years of smoking 1.8 2.7 7.6 -0.8 -1.9 -2.5 0.3 -1.0 -1.4 -1.2 -2.8 -1.6 -2.0 -1.5 -1.6 -2.2 -1.5 -0.0 -1.3
Impedance of whole body 1.0 5.3 19.4 4.4 3.3 1.2 -1.8 3.9 -0.2 2.0 3.1 -1.5 2.9 1.0 -0.2 0.9 2.2 -1.0 1.4
Leg fat mass (left) 0.9 3.4 8.3 -1.1 -0.6 -2.0 0.0 -1.6 -1.7 -2.3 1.8 -1.3 -2.4 -1.8 -1.2 -2.2 -2.2 -2.1 -2.9
Arm predicted mass (left) 0.8 4.3 19.9 -3.1 -1.6 -0.7 -0.5 -3.2 -0.3 -3.0 0.2 -1.7 -4.5 -1.6 -0.7 -1.4 -1.6 -0.5 -2.4