Hub : Genes

CAP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1250 0.0400 3.6e-04 -0.003 NA 0.023 NA 0.006 8.5e-01 NA 5.0e-03 NA 1.0e-01
2 GTEx Esophagus Mucosa 0.1230 0.0440 5.5e-04 0.021 NA 0.022 NA 0.049 1.5e-02 NA 1.2e-02 NA 3.4e-04
3 GTEx Heart Left Ventricle 0.4145 0.1048 2.9e-03 -0.004 NA 0.013 NA -0.004 6.6e-01 NA 6.1e-02 NA 6.3e-01
4 GTEx Nerve Tibial 0.1297 0.0396 2.2e-05 0.096 NA 0.097 NA 0.087 2.6e-07 NA 2.3e-07 NA 1.0e-06
5 GTEx Testis 0.1220 0.0480 2.8e-03 0.071 NA 0.068 NA 0.066 4.7e-04 NA 5.9e-04 NA 6.9e-04
6 GTEx Thyroid 0.1240 0.0440 2.1e-04 0.023 NA 0.038 NA 0.031 7.0e-03 NA 6.1e-04 NA 2.0e-03
7 NTR Blood 0.0175 0.0075 1.4e-03 0.013 0.009 0.010 0.011 0.014 2.5e-05 5.2e-04 3.3e-04 9.4e-05 1.8e-05
8 ROSMAP Brain Pre-frontal Cortex 0.1558 0.0308 5.6e-17 0.199 0.173 0.204 0.201 0.198 4.6e-25 9.7e-22 1.2e-25 2.5e-25 6.1e-25

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.2 0.5 -0.2 -0.1 0.0 -0.7 -0.7 -0.7 0.4 0.2
Bipolar Disorder or Schizophrenia 0.3 0.8 2.0 1.4 -1.3 0.0 -0.3 -0.3 0.1 -0.9 -1.2
Depressed Affect (Nagel 2018) 0.5 1.1 2.8 1.7 -0.3 0.0 1.0 1.1 1.4 -1.1 -0.7
Depression (Nagel 2018) 1.2 1.9 5.5 2.4 0.3 0.0 1.5 2.2 0.8 -1.1 -0.6
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.0 -0.3 -0.8 0.0 1.1 1.0 0.5 -1.7 -1.0
Neuroticism (Nagel 2018) 1.9 4.4 8.1 2.8 0.1 0.0 2.9 2.6 2.5 -2.3 -1.0
Schizophrenia (2018) 0.7 1.5 3.8 1.9 -1.6 0.0 0.3 0.3 0.7 -1.5 -1.7
Schizophrenia vs Biploar Disorder 0.4 0.6 2.3 1.5 -0.0 0.0 0.9 0.9 0.7 0.2 0.3
Worry (Nagel 2018) 1.3 2.7 6.3 2.5 -0.2 0.0 2.3 1.8 1.1 -2.0 -1.1
Alzheimer’s Disease (in mother) 0.3 0.4 1.3 -1.2 -0.5 0.0 -0.0 0.3 0.6 -0.6 -0.8
Alzheimer’s Disease (in father) 0.3 0.3 0.8 -0.1 -0.9 0.0 -0.4 -0.9 0.7 0.1 -0.1
Alzheimer’s Disease (including proxy) 0.1 0.2 0.7 -0.9 -0.5 0.0 -0.0 -0.1 0.8 -0.1 -0.3
Crohns Disease (2017) 0.3 0.7 2.5 -1.6 -0.5 0.0 -1.5 -0.7 -0.5 0.4 -0.4
Irritable Bowel Disease (IBD) 0.5 1.3 6.8 -2.6 0.3 0.0 -1.2 -0.4 -0.9 1.0 0.5
Ulcerative Colitis (UC) 0.9 1.7 5.7 -2.4 0.8 0.0 -0.8 -0.2 -1.2 1.7 1.5
Major Depression (MDD) 0.1 0.1 0.4 0.3 0.0 0.0 0.1 -0.4 0.7 0.2 0.2
Reaction Time 0.7 1.3 2.5 1.6 0.1 0.0 1.1 0.7 1.4 -1.6 -1.3
Verbal and Numeric Reasoning (VNR) 0.5 1.3 2.9 -1.4 -1.2 0.0 1.1 0.7 -0.7 -1.7 -1.3
Breast Cancer 0.3 0.8 2.8 -1.7 -0.5 0.0 -1.1 -0.7 -0.1 -0.9 -1.0
Ovarian Cancer 0.8 1.0 2.9 -1.2 1.7 0.0 0.9 0.4 -0.3 1.1 1.2
Prostate Cancer 0.8 1.2 3.5 -0.6 -0.1 0.0 -1.0 -0.4 -1.0 1.9 1.9
Age at First Birth 0.3 0.5 1.1 0.9 -1.1 0.0 -0.2 -0.2 -0.4 -0.9 -1.0
Bipolar Disorder (2011) 0.7 0.7 1.6 1.3 -0.3 0.0 -0.8 -1.2 -0.9 0.9 0.6
Body Mass Index (BMI) (2010) 0.3 0.3 1.2 -0.0 -0.5 0.0 0.2 -0.3 0.6 -1.1 -1.0
Coronary Artery Disease (CAD) 0.1 0.1 0.5 -0.7 0.2 0.0 -0.6 0.2 0.4 0.2 0.1
Crohns Disease (2012) 0.9 1.5 4.4 -0.9 0.8 0.0 -1.2 -0.3 -0.9 2.1 1.8
Mean Putamen Volume 0.4 0.4 2.0 -0.4 -0.3 0.0 0.3 -0.2 1.4 -0.8 -0.7
Fasting Glucose 0.9 1.1 3.1 0.8 -1.8 0.0 -1.3 -0.4 -0.1 -1.1 -1.3
HbA1C 1.0 1.1 3.6 -0.5 1.2 0.0 -0.5 0.4 -0.3 1.9 1.7
HDL Cholesterol 0.9 1.5 3.8 -1.5 1.1 0.0 0.2 0.3 -1.4 1.7 1.9
LDL Cholesterol 0.8 1.2 3.5 0.9 1.6 0.0 1.3 0.9 1.9 0.2 0.5
Lupus 0.8 1.3 4.1 -0.4 -0.4 0.0 -2.0 -1.1 -0.9 1.7 1.0
Neuroticism (2016) 1.8 2.6 7.3 2.7 -1.4 0.0 0.7 0.4 1.2 -2.2 -2.1
Primary Biliary Cirrhosis 0.4 0.6 3.2 -1.8 -0.3 0.0 -1.2 -0.4 0.2 0.3 -0.1
Rheumatoid Arthritis 0.1 0.2 1.1 -0.4 0.1 0.0 0.2 -1.0 -0.3 0.4 0.2
Schizophrenia (2014) 0.4 0.8 3.6 1.9 0.1 0.0 1.2 0.8 0.8 -0.3 -0.1
Triglycerides 0.4 0.7 3.2 1.8 -0.2 0.0 -0.0 -0.4 -0.2 -0.8 -1.2
Type 2 Diabetes (T2D) (2012) 0.5 0.6 1.8 -1.3 0.5 0.0 -0.9 -0.1 -0.6 1.0 0.7
Ulcerative Colitis 0.6 0.8 1.4 -1.1 0.1 0.0 -0.7 -0.8 -1.2 1.2 1.1
Blood Eosinophil Count 0.1 0.8 4.0 0.5 -1.0 0.0 -0.7 -0.6 -2.0 0.6 0.2
Blood Platelet Count 1.4 16.5 39.4 0.2 -0.1 0.0 -5.0 -6.3 -4.9 5.7 3.2
Blood Red Count 0.1 1.2 3.8 -1.0 1.9 0.0 0.3 1.6 0.5 0.9 1.2
Blood White Count 1.3 9.6 22.1 -0.2 -1.8 0.0 -4.5 -4.7 -4.3 3.2 1.4
Heel T-Score 0.4 3.4 15.0 -0.9 0.9 0.0 2.2 1.9 3.9 -1.4 -0.4
BMI 0.1 0.9 2.7 1.1 -0.2 0.0 0.8 0.4 -0.5 -1.4 -1.6
Height 0.7 13.9 50.7 -7.1 2.9 0.0 -2.2 -1.4 -3.3 4.5 3.8
Waist Hip Ratio (WHR) 0.5 2.2 6.3 -0.9 -2.5 0.0 -2.0 -1.7 -0.8 -0.8 -1.6
Systolic Blood Pressure 0.3 1.3 4.2 0.8 -1.5 0.0 -0.1 -0.2 0.7 -1.8 -2.0
Smoking Status 0.5 1.1 3.4 0.8 -1.8 0.0 -1.5 -1.4 -0.7 0.5 0.1
Allergy or Eczema 1.2 3.1 8.8 0.9 1.6 0.0 2.4 3.0 2.5 -1.0 -0.0
Cardiovascular Disease 0.1 0.3 1.0 -0.4 -1.0 0.0 -0.1 -0.4 -0.2 -0.7 -0.7
Hypothyroidism (self reported) 0.3 0.6 1.4 0.6 -1.0 0.0 -0.7 -1.2 -1.1 -0.3 -0.8
Respiratory disease 0.4 0.8 2.5 1.6 0.9 0.0 0.8 1.5 0.8 -0.2 0.2
Type 2 Diabetes (T2D) (2018) 0.1 0.1 0.5 -0.3 -0.7 0.0 0.0 0.3 0.2 0.2 0.4
Lung FEV1/FVC ratio 0.5 2.7 6.7 -2.0 -1.0 0.0 1.8 0.8 1.0 -2.6 -2.2
Lung FVC 0.5 2.8 7.8 0.4 1.9 0.0 2.8 2.4 0.4 0.9 2.0
Neuroticism 1.9 4.5 11.0 3.3 -0.6 0.0 2.2 1.6 2.3 -2.9 -1.9
Chronotype (morning person) 1.3 3.1 9.3 1.9 1.7 0.0 2.1 1.8 3.1 -0.9 -0.1
Hair Pigment 0.0 1.2 4.0 -1.4 -0.6 0.0 -0.9 -2.0 -1.0 -0.1 -1.3
Tanning 0.0 0.3 0.8 -0.2 0.9 0.0 0.6 0.8 0.2 0.2 0.6
Hand grip strength (left) 0.6 1.6 4.3 -0.2 1.9 0.0 0.0 0.5 0.5 2.1 2.1
Number of treatments/medications taken 2.4 4.4 8.9 2.6 -0.2 0.0 2.1 2.3 2.3 -3.0 -2.0
Average weekly spirits intake 0.1 0.1 0.3 0.2 0.3 0.0 0.5 0.3 0.4 -0.2 -0.1
Sensitivity / hurt feelings 2.5 4.2 8.1 2.6 -0.8 0.0 2.3 1.9 2.9 -2.6 -1.6
Frequency of depressed mood in last 2 weeks 1.2 1.7 7.8 2.8 -0.3 0.0 1.1 1.5 0.8 -1.2 -0.7
Hearing difficulty/problems: Yes 1.3 1.9 3.7 0.8 1.9 0.0 1.7 1.7 1.0 1.1 1.7
Relative age of first facial hair 1.1 2.3 5.1 -1.2 1.0 0.0 -1.7 -1.5 -1.7 2.3 1.5
Other serious medical condition/disability diagnosed by doctor 0.4 0.6 2.5 -1.6 -0.8 0.0 0.3 0.6 -0.5 -0.6 -0.5
Ever used hormone-replacement therapy (HRT) 0.8 1.0 5.9 -2.4 -0.2 0.0 -1.2 -0.7 -0.2 0.1 -0.1
Ever had hysterectomy (womb removed) 1.7 1.9 4.5 1.7 2.1 0.0 1.0 1.2 -0.1 1.3 1.8
Systolic blood pressure, automated reading 0.0 0.1 0.7 -0.8 -0.2 0.0 -0.1 0.2 0.5 -0.1 -0.1
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 4.3 0.1 -2.1 0.0 -1.2 -1.3 0.5 -1.2 -1.7
Angina 3.1 4.1 10.3 0.5 -3.1 0.0 -1.4 -0.9 1.3 -2.8 -3.2
Medication for hormone replacement therapy 0.5 0.6 1.6 0.1 0.2 0.0 0.6 0.9 1.3 -1.0 -0.8
Vitamin and mineral supplements 0.1 0.1 0.3 -0.2 -0.4 0.0 -0.3 -0.4 -0.2 -0.2 -0.6
Supplements: Zinc 0.3 0.3 0.9 0.5 -0.5 0.0 0.2 0.2 1.0 -0.8 -0.7
Medication: Co-codamol 0.2 0.2 0.5 -0.0 0.7 0.0 0.6 0.7 -0.4 -0.1 0.2
Medication: Metformin 0.1 0.2 0.5 -0.2 -0.3 0.0 -0.4 0.4 -0.3 0.6 0.7
Diabetes (father) 0.8 1.0 2.6 0.7 -1.2 0.0 -0.5 -0.5 1.3 -1.2 -1.6
Diabetes (mother) 1.1 1.4 4.4 -0.6 -2.1 0.0 -1.4 -0.9 -0.9 -1.0 -1.3
Severe depression (siblings) 1.0 1.2 2.4 -1.5 0.2 0.0 -1.0 -1.0 -1.3 1.6 0.9
Pack years adult smoking proportion 1.7 2.7 7.8 -0.9 -1.5 0.0 -2.8 -2.3 -1.8 1.2 -0.1
Impedance of leg (right) 0.7 3.4 8.6 -2.0 -1.6 0.0 -2.9 -2.9 -1.4 1.3 0.2
Leg fat-free mass (left) 0.1 0.7 3.2 -0.3 1.8 0.0 0.9 1.0 -0.4 -0.1 -0.1
Trunk fat percentage 0.3 1.1 3.7 -1.2 -0.6 0.0 -1.2 -1.1 -1.9 0.2 -0.6
Hand grip strength (right) 0.9 2.5 6.6 -1.1 2.6 0.0 -0.3 0.3 -0.0 2.5 2.3
Townsend deprivation index at recruitment 1.6 2.3 8.0 0.2 -2.8 0.0 -2.2 -1.8 -1.3 -0.2 -0.8
Current tobacco smoking 1.1 1.8 5.2 0.4 -2.3 0.0 -2.0 -1.5 -0.8 -0.6 -1.2
Average weekly fortified wine intake 0.9 1.0 3.1 -1.1 1.0 0.0 0.8 0.6 -1.8 0.9 1.0
Maternal smoking around birth 0.7 1.1 4.8 -0.7 -0.4 0.0 -0.4 -0.6 -2.2 1.1 1.1
Fed-up feelings 0.8 1.5 3.1 1.7 -1.8 0.0 0.2 -0.1 0.7 -1.7 -1.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 2.0 1.4 -0.5 0.0 0.3 0.5 -0.2 -0.8 -0.8
Relative age voice broke 1.0 1.5 4.0 -1.5 1.1 0.0 -1.0 -0.4 -1.0 2.0 1.5
Taking other prescription medications 1.3 2.0 4.7 2.2 0.3 0.0 1.6 2.0 1.0 -1.8 -1.0
Age when periods started (menarche) 1.6 3.8 10.1 -1.5 1.3 0.0 -1.1 -1.5 -2.3 3.2 2.8
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 5.3 2.3 0.8 0.0 0.7 1.3 0.8 -0.7 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.8 -0.8 0.0 0.0 0.1 -0.9 0.2 0.1 -0.2
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.5 -0.6 -0.7 0.0 0.0 0.7 -0.2 -0.2 -0.1
Qualifications: CSEs or equivalent 1.1 1.4 3.6 1.4 -1.1 0.0 -1.2 -1.2 -1.9 0.9 0.6
Serious illness, injury or assault to yourself 0.4 0.5 2.0 -0.4 1.4 0.0 0.6 0.8 -0.0 0.4 0.6
High blood pressure 0.1 0.3 0.9 -0.7 -0.0 0.0 0.9 0.8 0.3 -0.5 -0.1
Hayfever, allergic rhinitis or eczema 1.4 3.0 8.2 0.2 2.0 0.0 2.4 2.9 2.4 -0.7 0.1
Multivitamins +/- minerals 0.3 0.4 1.6 -0.3 0.7 0.0 0.6 0.5 -0.3 0.6 1.3
Stomach or abdominal pain in last month 0.7 0.9 3.1 -0.8 -0.9 0.0 -1.8 -1.2 -0.8 0.2 -0.4
Supplements: Glucosamine 0.9 1.2 3.2 1.0 1.3 0.0 0.7 0.7 -0.6 1.5 1.8
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.2 -0.4 0.4 0.0 -0.1 0.3 0.3 0.0 0.0
Medication: Atenolol 0.7 0.9 2.5 -1.0 -1.6 0.0 -0.8 -0.6 -1.1 -0.7 -1.0
Medication: Levothyroxine sodium 0.1 0.2 0.9 1.0 -0.2 0.0 -0.4 -0.5 -0.1 -0.1 -0.2
Sitting height 0.4 2.5 9.9 -3.1 2.0 0.0 0.2 0.8 -0.3 1.6 1.7
Chronic bronchitis/emphysema (father) 1.6 1.9 4.2 -1.4 -1.7 0.0 -1.9 -1.3 -2.1 1.0 0.3
High blood pressure (mother) 1.4 1.9 4.1 -1.1 -0.5 0.0 -2.0 -1.9 -1.9 1.6 0.4
Body mass index (BMI) 0.2 1.0 2.2 1.0 0.3 0.0 1.4 1.2 0.2 -1.5 -1.2
Impedance of leg (left) 0.8 3.8 9.7 -2.2 -1.4 0.0 -3.1 -2.8 -1.5 1.8 0.8
Leg predicted mass (left) 0.1 0.7 3.4 -0.3 1.8 0.0 1.0 1.0 -0.2 -0.1 -0.1
Trunk fat mass 0.2 0.7 2.7 -1.3 0.2 0.0 -0.7 -0.6 -1.7 0.3 -0.3
Waist circumference 0.1 0.4 1.2 -1.1 -0.1 0.0 -0.2 -0.2 -0.9 -0.6 -0.9
Number of incorrect matches in round 1.8 3.0 6.2 1.7 1.8 0.0 2.4 2.5 2.3 -0.4 0.8
Past tobacco smoking 0.2 0.3 1.2 -1.1 0.7 0.0 -0.6 -0.5 -0.2 0.0 -0.7
Alcohol usually taken with meals 0.8 1.3 6.2 -2.5 0.0 0.0 -1.2 -1.2 -1.0 0.5 -0.1
Nervous feelings 1.4 2.7 6.7 2.6 -1.2 0.0 1.4 1.1 1.9 -2.1 -1.5
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 7.0 2.6 0.1 0.0 1.7 2.0 1.2 -1.6 -0.9
Hearing difficulty/problems with background noise 0.5 0.8 1.8 0.1 0.1 0.0 1.4 1.3 1.3 0.3 1.1
Hair/balding pattern: Pattern 2 0.1 0.2 0.8 -0.1 -0.3 0.0 0.0 -0.1 0.3 -0.5 -0.9
Had menopause 1.0 1.3 4.5 -2.1 -0.6 0.0 0.8 0.8 1.1 -1.5 -0.9
Had other major operations 0.8 0.9 1.9 1.2 1.2 0.0 0.7 1.0 0.1 1.0 1.4
Forced vital capacity (FVC) 0.4 1.6 3.8 -1.9 0.9 0.0 -0.3 -0.6 -1.4 1.9 1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 2.3 -1.0 -0.7 0.0 -0.4 -1.5 0.2 -0.2 -0.9
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 1.9 0.6 -1.4 0.0 -0.0 -0.1 0.8 -1.1 -1.4
Qualifications: None of the above 0.2 0.5 1.4 0.1 -0.0 0.0 -1.2 -1.1 -0.2 0.9 0.7
Financial difficulties in last 2 years 0.0 0.1 0.3 0.5 -0.1 0.0 -0.1 -0.3 -0.4 0.1 0.0
Mouth/teeth dental problems 0.6 0.9 2.4 -0.6 0.8 0.0 -0.9 0.0 -1.0 1.5 1.4
Heart attack 2.5 3.3 7.8 2.2 -1.8 0.0 0.4 0.4 1.9 -2.8 -2.5
Allergy 1.4 3.1 9.1 -0.7 -2.1 0.0 -2.6 -3.0 -2.0 0.6 -0.3
Pain all over the body in last month 0.5 0.5 1.1 -1.0 0.2 0.0 0.7 0.1 0.9 -0.8 -1.0
Diabetes (self-reported) 0.2 0.3 0.6 -0.6 -0.8 0.0 -0.5 -0.3 -0.2 0.7 0.7
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.1 0.8 1.2 0.0 1.4 1.4 0.9 -0.4 0.0
Medication: Ramipril 0.8 1.1 3.0 0.3 -0.8 0.0 0.5 0.7 1.4 -1.7 -1.5
Medication: Simvastatin 0.8 1.1 2.7 -0.1 0.9 0.0 1.5 1.4 1.6 -1.1 -0.5
Fluid intelligence score 0.6 1.3 3.7 -1.1 -1.1 0.0 0.9 0.8 -0.0 -1.9 -1.6
Illnesses of siblings 1.5 2.1 6.7 0.3 2.6 0.0 0.5 0.5 -0.1 2.0 2.3
Neuroticism score 2.3 4.7 10.0 2.9 -1.6 0.0 1.4 0.9 2.8 -3.2 -2.5
Weight 0.1 0.6 1.8 -1.4 1.3 0.0 0.2 0.4 -0.9 0.2 -0.1
Impedance of arm (right) 1.0 4.8 10.3 -1.9 -1.6 0.0 -3.2 -2.9 -2.8 2.1 1.1
Arm fat percentage (right) 0.1 0.3 1.5 -0.3 -0.4 0.0 -0.2 -0.3 -1.2 -0.4 -0.7
Trunk fat-free mass 0.2 1.2 4.9 -1.1 2.2 0.0 1.2 1.3 0.3 0.0 0.1
Hip circumference 0.1 0.6 1.9 -1.4 1.4 0.0 0.2 0.2 -0.8 0.3 0.0
Time employed in main current job 0.5 0.5 2.2 0.3 0.8 0.0 1.0 1.5 0.6 -0.3 0.4
Alcohol intake versus 10 years previously 0.1 0.1 0.3 0.5 0.4 0.0 -0.5 0.1 0.0 0.3 0.4
Father’s age at death 0.3 0.3 0.8 0.9 0.2 0.0 0.7 0.5 0.8 -0.5 -0.5
Worrier / anxious feelings 2.3 4.3 8.6 2.1 0.2 0.0 2.8 2.3 2.9 -2.6 -1.2
Frequency of tiredness / lethargy in last 2 weeks 1.7 2.8 6.1 2.5 1.2 0.0 2.2 2.4 1.8 -1.0 -0.1
Falls in the last year 0.7 0.9 3.3 1.8 -0.8 0.0 -0.2 -0.5 -0.9 -1.0 -1.0
Hair/balding pattern: Pattern 3 0.7 1.0 3.6 1.1 -1.9 0.0 -0.8 -1.1 0.1 -0.9 -1.0
Number of live births 0.8 1.1 3.7 -0.3 -1.1 0.0 -1.7 -1.9 0.5 0.2 -0.6
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 4.6 -2.1 0.6 0.0 0.0 -0.5 -1.2 1.4 1.1
Pulse rate 0.2 0.3 1.4 -0.4 -0.1 0.0 -1.2 -0.6 -0.2 0.5 -0.0
Happiness 0.3 0.4 0.9 0.7 -0.5 0.0 -0.9 -0.4 -0.3 0.8 0.7
Noisy workplace 1.3 1.6 5.3 0.2 1.5 0.0 2.3 2.0 0.9 0.2 1.0
Qualifications: A levels/AS levels or equivalent 0.4 0.8 2.2 -1.2 0.4 0.0 0.8 1.5 0.8 -0.9 -0.6
Serious illness, injury or assault of a close relative in last 2 years 2.5 2.8 6.9 -1.1 -0.2 0.0 -2.2 -2.0 -2.6 2.0 1.2
Mouth/teeth dental problems: Dentures 0.4 0.8 1.8 -0.8 -0.3 0.0 0.9 0.5 1.1 -1.3 -1.2
Asthma 0.4 0.8 2.0 1.4 0.6 0.0 1.2 1.3 0.9 -0.2 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.4 -0.1 -1.0 0.0 -1.0 -0.6 0.2 -1.0 -1.6
Medication: Cholesterol lowering 0.8 1.2 4.0 0.2 -1.0 0.0 1.0 0.7 0.8 -2.0 -1.5
Depression (self-reported) 1.5 1.8 4.7 -1.1 -1.7 0.0 -1.4 -2.2 -1.6 -0.1 -0.9
Medication: Lansoprazole 0.1 0.1 0.6 0.2 -0.3 0.0 -0.4 -0.2 -0.8 0.2 -0.1
Prospective memory result 0.2 0.3 0.9 0.3 -0.5 0.0 0.9 -0.2 0.7 -0.6 -0.4
Lung cancer (father) 0.4 0.5 1.2 1.0 -0.9 0.0 -0.8 -1.1 -0.2 -0.2 -0.6
Illnesses of mother 0.9 1.1 2.9 1.2 0.7 0.0 1.7 1.4 1.1 -1.0 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.5 1.8 -1.4 0.7 0.0 0.4 0.1 -0.5 0.9 0.9
Pulse wave Arterial Stiffness index 1.4 1.6 4.2 0.6 0.6 0.0 1.7 2.1 1.6 -1.4 -0.7
Impedance of arm (left) 0.9 4.0 8.6 -2.2 -1.1 0.0 -2.9 -2.7 -2.3 2.0 1.0
Arm fat mass (right) 0.1 0.3 0.6 -0.1 0.4 0.0 0.5 0.5 -0.6 -0.7 -0.8
Trunk predicted mass 0.2 1.2 5.0 -1.1 2.2 0.0 1.2 1.3 0.2 0.1 0.2
Standing height 0.8 7.7 24.4 -4.9 2.4 0.0 -2.3 -1.6 -2.2 3.6 2.4
Length of working week for main job 0.3 0.4 0.9 -0.8 -0.3 0.0 -0.7 -1.0 -0.6 0.4 0.1
Exposure to tobacco smoke at home 1.5 1.7 3.8 -1.2 -1.6 0.0 -1.8 -1.9 -1.4 0.5 -0.4
Breastfed as a baby 0.8 1.0 5.4 -0.2 2.3 0.0 0.5 0.8 0.1 1.0 0.9
Tense / ‘highly strung’ 1.0 1.7 3.7 1.9 -0.3 0.0 1.7 1.2 1.3 -1.6 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 1.0 3.2 0.0 -1.4 0.0 -0.3 -0.7 0.1 -1.4 -1.8
Hair/balding pattern: Pattern 4 0.6 1.5 3.5 -0.7 1.8 0.0 1.1 0.8 -0.3 1.5 1.9
Birth weight of first child 1.6 2.9 8.2 0.7 2.9 0.0 1.0 1.8 1.8 1.8 2.1
Peak expiratory flow (PEF) 1.3 3.0 8.5 -2.0 2.0 0.0 0.7 0.7 -0.6 2.5 2.9
Pulse wave reflection index 0.3 0.4 1.3 0.7 -1.1 0.0 0.4 0.1 -0.9 -0.5 -0.5
Ever highly irritable/argumentative for 2 days 2.7 3.2 7.7 0.0 -1.8 0.0 -2.6 -2.8 -2.4 1.5 0.6
Loud music exposure frequency 0.2 0.3 0.9 0.9 0.7 0.0 -0.0 0.0 -0.3 0.5 0.5
Qualifications: O levels/GCSEs or equivalent 0.7 1.0 3.4 0.1 1.1 0.0 1.5 1.9 0.9 -0.9 -0.2
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 2.8 0.7 -0.3 0.0 -1.1 -1.7 -1.5 1.2 0.8
Blood clot in the leg (DVT) 1.3 1.6 4.8 -1.1 1.5 0.0 2.0 2.2 0.7 -0.4 0.3
Medication: Paracetamol 0.4 0.7 2.8 1.7 0.5 0.0 -0.4 0.1 -0.6 1.0 0.9
Headache pain in last month 0.2 0.3 0.9 0.6 -0.6 0.0 -0.9 -0.9 -0.2 -0.0 -0.3
Medication for cholesterol, blood pressure or diabetes 1.3 2.1 6.5 -0.1 0.4 0.0 -1.7 -1.4 -1.3 2.5 1.9
Glaucoma (self-reported) 0.2 0.3 0.6 -0.2 0.3 0.0 0.0 -0.8 -0.6 0.8 0.6
Gout (self-reported) 0.3 0.4 1.0 0.5 0.8 0.0 0.6 1.0 -0.3 -0.6 -0.8
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.5 0.7 -0.1 0.0 0.1 -0.2 -0.2 -0.6 -0.6
Medication: Amlodipine 2.2 3.1 7.5 0.2 0.6 0.0 2.7 1.9 2.7 -2.2 -1.3
Medication: Ventolin 100micrograms inhaler 1.7 2.2 4.2 1.4 0.6 0.0 1.9 2.0 1.9 -1.7 -0.7
Birth weight 0.8 1.7 5.7 0.7 2.4 0.0 1.5 1.9 1.0 0.1 0.7
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.6 -1.0 -0.1 0.0 -0.5 -0.1 -0.5 1.1 1.3
High blood pressure (siblings) 1.2 1.7 4.7 0.5 -2.1 0.0 -0.2 -0.4 0.7 -1.9 -2.2
Forced vital capacity (FVC), Best measure 0.3 1.0 2.5 -1.5 1.0 0.0 0.2 -0.0 -0.5 1.6 1.5
Body fat percentage 0.2 0.8 2.6 -1.0 -0.6 0.0 -1.0 -0.9 -1.6 -0.1 -0.7
Leg fat percentage (right) 0.1 0.5 1.6 -0.5 -0.7 0.0 -0.2 -0.2 -0.8 -0.8 -1.3
Arm fat-free mass (right) 0.1 0.8 2.5 -1.4 1.6 0.0 0.7 1.0 0.2 -0.4 -0.4
Exposure to tobacco smoke outside home 0.4 0.6 1.5 0.8 -0.8 0.0 -0.5 -0.3 0.5 -1.1 -1.2
Comparative body size at age 10 1.0 2.9 7.5 0.3 -1.1 0.0 1.9 2.2 1.4 -2.7 -1.9
Number of full brothers 0.5 0.7 2.6 0.3 -1.6 0.0 0.3 0.3 0.2 -1.2 -1.0
Worry too long after embarrassment 2.8 4.8 9.5 2.7 -0.3 0.0 2.6 2.2 3.1 -2.7 -1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 6.2 0.3 -1.8 0.0 -0.5 -1.4 0.5 -1.9 -2.5
Wheeze or whistling in the chest in last year 0.2 0.3 0.8 0.9 -0.4 0.0 0.1 0.1 -0.9 -0.5 -0.5
Number of children fathered 0.4 0.4 1.2 -0.0 0.4 0.0 0.2 -0.3 -1.1 1.0 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.0 0.5 1.1 0.0 1.4 0.7 0.3 0.9 1.1
Age at first live birth 0.4 0.7 1.9 0.8 1.4 0.0 1.4 1.1 0.0 -0.4 -0.1
Pulse wave peak to peak time 1.6 1.8 4.6 -1.0 -0.2 0.0 -1.7 -2.1 -1.7 1.6 0.9
Health satisfaction 0.2 0.3 2.2 -1.5 -0.0 0.0 -0.1 0.1 -0.0 -0.1 -0.2
Shortness of breath walking on level ground 1.0 1.2 3.3 -0.2 -1.0 0.0 0.4 0.5 1.8 -1.6 -1.4
Qualifications: College or University degree 0.5 1.5 3.7 -1.9 -0.9 0.0 -1.5 -1.2 -1.5 1.1 0.5
Eye problems/disorders: None of the above 1.5 1.7 6.5 0.6 0.4 0.0 1.2 1.3 2.6 -1.6 -1.0
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.7 -1.3 -0.0 0.0 -0.8 -1.0 -0.7 0.5 0.1
Emphysema/chronic bronchitis 0.3 0.4 1.5 -1.2 -0.8 0.0 -0.3 -0.4 0.1 -0.5 -0.7
Medication for pain relief, constipation, heartburn 0.3 0.5 1.2 -1.0 1.1 0.0 0.3 -0.4 -0.4 0.8 0.8
Neck or shoulder pain in last month 0.3 0.4 1.0 -0.3 -0.8 0.0 -1.0 -0.8 -0.1 -0.4 -0.6
Medication: Blood pressure 1.5 2.6 5.9 0.9 0.1 0.0 2.1 1.8 1.7 -2.4 -1.8
Angina (self-reported) 3.1 4.1 10.4 0.3 -3.2 0.0 -1.6 -1.1 0.9 -2.8 -3.2
Migraine (self-reported) 1.2 1.5 2.6 -1.2 0.2 0.0 -1.5 -1.6 -1.5 1.6 0.7
Medication: Ibuprofen 0.7 0.8 2.8 0.3 -0.9 0.0 -0.2 -0.0 0.9 -1.5 -1.7
Medication: Allopurinol 0.6 0.7 2.1 1.4 0.9 0.0 0.9 1.3 -0.2 -0.4 -0.6
Medication: Omeprazole 0.8 1.0 1.9 -0.9 -1.3 0.0 -1.1 -0.8 -1.4 -0.6 -1.1
Medication: Seretide 50 evohaler 2.6 3.0 11.2 -0.2 -3.3 0.0 -1.2 -1.7 -0.9 -1.6 -2.2
Mean time to correctly identify matches 0.6 1.1 2.0 1.2 0.1 0.0 1.2 0.5 1.3 -1.4 -1.3
Heart disease (mother) 0.3 0.4 1.2 -0.5 -1.1 0.0 -0.4 -0.5 -0.5 -0.6 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.4 1.6 3.8 -1.4 -1.5 0.0 -1.2 -1.9 -1.8 -0.4 -0.8
Whole body fat mass 0.1 0.2 1.0 -0.6 0.4 0.0 -0.1 -0.0 -1.0 -0.2 -0.6
Leg fat mass (right) 0.1 0.3 1.1 -0.2 0.2 0.0 0.3 0.2 -0.6 -0.8 -1.1
Arm predicted mass (right) 0.2 0.9 3.2 -1.0 1.8 0.0 1.0 1.2 0.6 -0.5 -0.5
Pulse rate, automated reading 1.2 3.9 13.2 -0.1 1.4 0.0 -1.9 -1.4 -0.8 3.6 3.1
Alcohol intake frequency. 0.4 0.9 3.3 -1.8 -0.5 0.0 -1.1 -1.6 -0.2 0.2 -0.0
Comparative height size at age 10 0.4 2.0 6.4 -2.5 1.3 0.0 -0.9 -0.6 -1.1 1.9 1.3
Number of full sisters 0.4 0.5 1.1 0.5 -1.0 0.0 0.1 -0.5 1.0 -1.0 -0.9
Suffer from ‘nerves’ 0.6 1.0 3.2 0.9 -1.8 0.0 -0.1 -0.9 0.3 -1.1 -1.2
Overall health rating 0.1 0.3 0.7 0.7 -0.0 0.0 0.6 0.5 -0.3 -0.9 -0.6
Chest pain or discomfort 1.1 1.6 4.1 -0.7 -1.9 0.0 -1.2 -0.4 -0.2 -1.6 -2.0
Had major operations 1.7 2.0 5.7 0.1 -2.4 0.0 -1.9 -1.8 -1.6 -0.4 -1.1
Age at last live birth 0.9 1.3 4.1 2.0 1.3 0.0 1.0 0.9 1.3 -0.8 -0.6
Family relationship satisfaction 0.2 0.3 1.5 0.5 -1.2 0.0 -0.2 -0.4 -0.4 -0.2 -0.3
Leg pain on walking 0.4 0.5 1.5 -0.6 0.3 0.0 -0.3 -0.6 -0.9 1.2 1.0
Qualifications: NVQ or HND or HNC or equivalent 1.8 2.1 5.1 0.2 -2.2 0.0 -1.6 -1.8 -1.9 -0.8 -1.6
Commuting to job workplace: Car/motor vehicle 0.8 1.0 2.8 -1.7 -0.2 0.0 -1.2 -0.9 -1.5 -0.0 -0.7
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 2.6 1.5 0.3 0.0 1.2 0.5 1.6 -0.5 -0.2
Medication: Aspirin 0.2 0.3 0.7 -0.2 -0.8 0.0 0.3 0.3 0.6 -0.7 -0.5
Supplements: Vitamin C 0.6 0.7 2.3 0.7 0.8 0.0 1.5 1.4 0.3 -0.4 0.2
Knee pain experienced in last month 0.8 1.3 2.8 1.1 1.5 0.0 1.5 1.7 1.2 0.0 0.5
Hypertension (Self-reported) 0.1 0.4 0.8 -0.7 -0.5 0.0 0.9 0.8 0.4 -0.8 -0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.3 0.8 -0.6 0.0 0.1 0.7 0.0 -1.5 -1.0
Illnesses of father: Heart disease 0.5 0.7 2.1 1.2 -0.4 0.0 0.9 0.4 0.1 -1.4 -1.1
Illnesses of siblings: Diabetes 0.2 0.2 0.9 0.0 -0.1 0.0 -0.4 -0.3 -0.9 0.5 0.4
Smoking status: Previous 0.4 0.5 1.5 0.7 -1.2 0.0 0.8 0.5 0.5 -1.0 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.0 -2.0 0.2 0.0 -1.7 -1.4 -0.7 1.0 0.4
Whole body fat-free mass 0.2 1.0 4.3 -0.7 2.1 0.0 1.1 1.3 0.2 -0.1 -0.0
Leg fat-free mass (right) 0.1 0.7 3.3 -0.3 1.8 0.0 0.8 1.0 -0.5 0.2 0.1
Arm fat percentage (left) 0.1 0.3 1.0 -0.3 -0.3 0.0 -0.0 -0.2 -1.0 -0.5 -0.8
Average weekly red wine intake 0.6 0.9 3.8 -2.0 1.0 0.0 0.5 -0.1 -0.4 0.8 1.0
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.5 1.2 -0.4 0.0 0.3 -0.0 0.6 -1.0 -0.7
Mood swings 1.3 2.3 4.7 1.8 -1.7 0.0 0.3 -0.0 1.9 -2.2 -2.0
Loneliness, isolation 0.7 0.9 2.0 1.3 -0.0 0.0 1.2 1.3 1.4 -0.4 0.3
Long-standing illness, disability or infirmity 0.5 0.8 2.2 1.5 0.2 0.0 1.2 1.4 0.6 -0.3 0.4
Ever had bowel cancer screening 0.5 0.5 3.2 -1.8 -0.1 0.0 0.2 0.4 0.2 -0.8 -0.5
Diabetes diagnosed by doctor 0.1 0.1 0.6 0.4 -0.8 0.0 -0.3 -0.2 0.1 0.2 0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 3.7 0.2 1.4 0.0 -1.0 -0.0 -1.3 1.9 1.8
Friendships satisfaction 0.4 0.5 1.5 0.6 -0.6 0.0 0.4 0.3 -0.9 1.0 1.2
Qualifications: nursing, teaching 0.9 1.3 4.7 0.3 1.0 0.0 2.0 2.2 0.8 -0.6 -0.1
Commuting to job workplace: Walk 1.8 1.9 5.6 -0.1 -0.1 0.0 -0.9 -1.0 -2.4 2.1 1.9
Eye problems/disorders: Cataract 2.5 2.9 10.2 -0.2 0.6 0.0 -0.9 -1.0 -3.2 2.6 2.0
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.7 0.7 0.2 0.0 0.8 -0.0 -0.6 -0.1 -0.1
Medication for cholesterol 0.3 0.5 2.4 1.5 0.0 0.0 0.9 0.8 0.0 -0.6 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.6 0.9 1.0 0.0 0.1 0.3 0.3 1.0 1.3
Back pain experienced in last month 0.3 0.4 1.4 0.0 -1.2 0.0 -1.0 -0.8 0.2 -0.5 -0.5
Mineral and other dietary supplements 1.3 1.7 3.9 -1.6 -0.7 0.0 -2.0 -1.9 -1.6 0.6 -0.3
Breast cancer (self-reported) 0.3 0.4 2.7 1.6 -0.1 0.0 0.1 -0.2 0.2 -0.1 0.0
Asthma (self-reported) 0.5 1.0 2.2 1.5 0.7 0.0 1.3 1.5 1.0 -0.2 0.4
Osteoporosis (self-reported) 1.2 1.5 4.9 -0.2 -2.2 0.0 -0.5 -0.6 0.1 -1.6 -1.9
Osteoarthritis (self-reported) 4.0 5.1 11.6 0.8 3.4 0.0 2.8 3.3 2.4 0.6 2.0
Medication: Aspirin 0.1 0.2 0.8 -0.4 -0.9 0.0 0.1 0.2 0.2 -0.5 -0.4
Medication: Gliclazide 0.1 0.1 0.5 -0.6 -0.5 0.0 -0.3 0.1 -0.7 0.1 0.1
Illnesses of father: None of the above (group 1) 0.1 0.1 0.4 0.1 0.6 0.0 0.0 -0.0 0.6 0.2 0.2
Smoking status: Current 0.7 1.1 3.3 0.7 -1.6 0.0 -1.8 -1.3 -0.9 0.2 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 1.0 -0.3 0.2 0.0 1.0 0.2 -0.3 0.2 0.4
Whole body water mass 0.2 0.9 4.0 -0.8 2.0 0.0 1.0 1.1 0.1 -0.0 -0.0
Leg predicted mass (right) 0.1 0.7 3.7 -0.4 1.9 0.0 0.8 1.0 -0.5 0.3 0.2
Arm fat mass (left) 0.1 0.3 0.4 -0.2 0.6 0.0 0.6 0.5 -0.4 -0.6 -0.7
Number of self-reported non-cancer illnesses 0.7 1.3 4.0 0.3 0.8 0.0 1.7 2.0 1.3 -0.8 0.1
Average weekly champagne plus white wine intake 0.5 0.6 1.7 0.3 -0.0 0.0 0.6 1.1 1.3 -1.0 -0.9
Miserableness 0.5 0.8 2.9 1.7 -1.6 0.0 -0.4 -0.4 0.5 -0.7 -0.6
Guilty feelings 1.8 2.7 6.9 1.0 -0.4 0.0 1.9 2.0 2.6 -2.1 -1.0
Wears glasses or contact lenses 0.4 0.5 1.8 -0.6 0.7 0.0 1.0 1.3 0.3 0.1 0.4
Ever taken oral contraceptive pill 0.3 0.4 1.4 0.6 -1.2 0.0 -0.2 -0.4 0.5 -0.6 -0.6
Hearing aid user 1.1 1.2 2.2 1.4 1.2 0.0 1.3 1.5 1.4 -0.3 0.4
Mother’s age at death 1.0 1.2 3.5 0.4 1.7 0.0 1.5 1.9 0.8 -0.3 0.6
Financial situation satisfaction 0.6 0.7 1.9 1.4 -0.3 0.0 -1.0 -0.9 -1.1 0.7 0.2
Tinnitus: Yes, now most or all of the time 2.0 2.4 10.6 3.2 1.1 0.0 1.8 1.6 0.0 0.5 1.1
Commuting to job workplace: Public transport 0.2 0.2 0.8 0.1 0.4 0.0 0.8 0.9 0.4 -0.4 -0.1
Eye problems/disorders: Glaucoma 1.1 1.3 4.1 0.2 2.0 0.0 1.3 1.2 0.6 0.9 1.4
Medication: Blood pressure 0.4 0.7 1.8 -1.3 -0.7 0.0 -1.2 -1.1 -0.8 0.4 0.2
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.0 1.4 -0.8 0.0 -0.9 -1.0 -0.7 0.8 0.2
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.5 0.4 -0.2 0.0 1.2 1.2 0.6 -0.9 -0.4
High cholesterol (Self-reported) 0.0 0.1 0.4 -0.6 -0.1 0.0 0.2 -0.0 -0.1 -0.4 -0.3
Medication: Bendroflumethiazide 0.2 0.4 2.1 1.5 -0.7 0.0 0.2 0.1 0.2 -0.5 -0.1
Medication: Paracetamol 0.2 0.3 2.0 1.4 0.3 0.0 -0.4 -0.1 -0.4 0.5 0.4
Medication: Lisinopril 0.6 0.8 1.7 -0.3 1.2 0.0 0.6 0.1 -1.0 1.3 1.2
Medication: Atorvastatin 1.0 1.2 4.3 -0.2 -2.1 0.0 -1.1 -1.3 -0.6 -0.9 -1.1
Illnesses of father: High blood pressure 0.4 0.4 1.3 -0.0 -0.1 0.0 0.5 0.8 0.7 -1.1 -0.9
Alcohol drinker status: Never 0.2 0.2 0.5 -0.2 -0.5 0.0 -0.2 -0.6 -0.5 0.6 0.7
Ever smoked 0.1 0.2 0.7 0.1 -0.8 0.0 -0.4 -0.2 -0.6 0.4 0.6
Basal metabolic rate 0.1 0.7 3.5 -0.7 1.9 0.0 0.9 1.1 -0.1 -0.1 -0.1
Leg fat percentage (left) 0.1 0.3 1.1 -0.5 -0.6 0.0 0.1 0.1 -0.6 -0.9 -1.1
Arm fat-free mass (left) 0.1 0.7 2.4 -1.0 1.6 0.0 0.8 1.1 0.1 -0.2 -0.2
Number of operations (self-reported) 0.7 1.1 4.5 0.6 -1.1 0.0 -1.4 -0.8 -2.1 0.5 -0.1
Average weekly beer plus cider intake 3.6 5.3 12.0 0.3 -2.7 0.0 -3.3 -3.3 -3.5 0.9 -0.5
Irritability 1.3 2.2 6.6 0.0 -1.7 0.0 -0.1 -0.2 1.4 -2.5 -2.6
Risk taking 0.6 0.8 1.8 1.0 0.1 0.0 -0.4 -1.0 -1.4 1.3 0.8
Ever had prostate specific antigen (PSA) test 0.5 0.5 1.5 0.3 0.2 0.0 0.8 1.1 1.2 0.4 0.8
Fractured/broken bones in last 5 years 0.5 0.6 1.7 1.3 -0.9 0.0 -0.2 -0.6 -1.1 -0.5 -0.7
Age started oral contraceptive pill 0.9 1.1 7.5 -2.7 0.9 0.0 -0.0 0.1 0.4 0.4 0.6
Diastolic blood pressure, automated reading 0.4 1.4 3.8 0.1 1.9 0.0 1.1 1.9 1.0 0.6 1.1
Ever depressed for a whole week 0.4 0.5 1.9 0.8 -1.4 0.0 -0.7 -0.7 0.4 -0.4 -0.5
Unable to work because of sickness or disability 0.8 1.0 2.0 -0.3 -1.4 0.0 -1.2 -1.4 -0.0 -0.8 -1.4
Commuting to job workplace: Cycle 0.8 0.9 2.0 -1.0 -1.3 0.0 -0.6 -0.4 1.4 -1.1 -1.1
Myopia 1.1 1.6 4.3 -1.0 0.6 0.0 2.1 2.0 1.5 -1.0 -0.2
Vascular/heart problems diagnosed by doctor 0.2 0.6 1.7 0.2 0.6 0.0 -0.9 -0.7 -0.8 1.3 1.0
Cholesterol lowering medication 0.3 0.5 2.1 -1.5 -0.2 0.0 -0.7 -0.7 -0.4 0.5 0.3
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.1 -1.1 -0.6 0.0 -0.7 -0.3 -0.9 -0.5 -1.0
Pain experienced in last month 0.4 0.7 1.9 0.4 -0.5 0.0 1.1 1.0 0.6 -1.4 -1.1
Supplements: Calcium 0.4 0.5 1.5 0.3 -0.4 0.0 0.8 0.8 1.2 -0.8 -0.2
Basal cell carcinoma (self-reported) 0.9 1.1 4.4 -0.9 -2.1 0.0 -0.8 -1.2 -0.3 -0.7 -1.0
Heart attack/myocardial infarction (self-reported) 2.7 3.4 8.9 1.8 -2.0 0.0 0.3 0.3 1.9 -3.0 -2.8
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 3.8 -1.4 1.3 0.0 1.7 2.0 0.3 -0.4 0.3
Heart disease (siblings) 0.3 0.3 1.3 -0.5 0.1 0.0 1.0 1.2 -0.2 -0.1 0.3
Alcohol drinker status: Previous 0.3 0.3 1.5 -1.2 0.1 0.0 0.4 -0.2 0.2 -0.6 -0.6
Pack years of smoking 1.3 1.9 5.6 -0.8 -1.4 0.0 -2.4 -2.0 -1.3 1.0 -0.0
Impedance of whole body 1.1 5.4 13.3 -2.4 -1.8 0.0 -3.6 -3.3 -2.2 2.0 0.8
Leg fat mass (left) 0.1 0.3 0.8 -0.2 0.3 0.0 0.5 0.4 -0.5 -0.8 -0.9
Arm predicted mass (left) 0.1 0.7 2.0 -1.1 1.4 0.0 0.9 1.1 0.1 -0.4 -0.3