TWAS hub - CAPZA2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0190	3.4e-03	-0.001	0.006	0.000	0.005	0.001	4.1e-01	6.1e-02	2.9e-01	6.6e-02	2.3e-01
2	GTEx	Artery Tibial	0.1059	0.0327	1.2e-04	0.082	NA	0.067	NA	0.077	5.8e-07	NA	6.3e-06	NA	1.3e-06
3	GTEx	Breast Mammary Tissue	0.1180	0.0510	9.0e-03	0.049	NA	0.030	NA	0.034	1.5e-03	NA	1.1e-02	NA	7.1e-03
4	GTEx	Breast Mammary Tissue (Male)	0.1420	0.0976	9.2e-02	-0.002	NA	0.016	NA	0.064	3.7e-01	NA	1.3e-01	NA	1.4e-02
5	GTEx	Esophagus Mucosa	0.1500	0.0550	2.6e-03	0.021	NA	0.097	NA	0.041	1.4e-02	NA	4.8e-07	NA	9.1e-04
6	GTEx	Esophagus Muscularis	0.2030	0.0520	3.2e-06	0.121	NA	0.150	NA	0.148	9.0e-08	NA	2.3e-09	NA	2.9e-09
7	GTEx	Nerve Tibial	0.0870	0.0365	5.1e-03	0.043	NA	0.038	NA	0.059	4.8e-04	NA	1.0e-03	NA	5.4e-05
8	METSIM	Adipose	0.0496	0.0169	1.1e-04	0.037	0.022	0.021	0.021	0.024	2.7e-06	2.7e-04	3.1e-04	3.5e-04	1.2e-04
9	YFS	Blood	0.1219	0.0291	0.0e+00	0.051	0.065	0.076	0.090	0.057	3.6e-16	1.7e-20	1.1e-23	7.6e-28	6.5e-18
10	TCGA	Lung Adenocarcinoma	0.0298	0.0183	5.0e-03	0.032	0.017	0.016	NA	0.024	1.0e-04	4.0e-03	4.4e-03	NA	6.8e-04
11	TCGA	Prostate Adenocarcinoma	0.0491	0.0284	4.1e-04	0.047	0.035	0.041	NA	0.044	1.0e-05	1.3e-04	3.7e-05	NA	2.2e-05
12	TCGA	Thyroid Carcinoma	0.0410	0.0280	7.9e-03	-0.002	0.008	0.003	NA	0.002	5.4e-01	5.3e-02	1.4e-01	NA	2.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Blood Platelet Count	13.7	158.8	234.1	9.1	15.3	15.3	13.1	9.0	14.4	9.4	14.6	8.6	12.7	15.3	11.1
Multivitamins +/- minerals	6.1	7.7	13.8	2.5	2.6	2.6	2.3	2.6	3.1	3.4	2.9	1.8	2.7	2.6	3.7
Chest pain or discomfort	5.6	8.1	12.4	3.3	3.0	2.8	1.7	1.1	3.0	3.1	2.9	3.5	2.8	2.9	3.2
Noisy workplace	5.2	6.5	12.7	3.6	2.3	2.3	1.4	0.6	2.7	3.5	2.5	1.8	2.4	2.2	3.6
Alzheimer’s Disease (in father)	4.8	5.2	8.8	1.4	2.4	2.5	3.0	1.7	2.7	2.2	2.6	1.2	2.0	2.5	2.4
Type 2 Diabetes (T2D) (2012)	4.7	5.4	8.6	-2.3	-2.5	-2.5	-1.5	-1.5	-2.4	-2.5	-2.9	-2.5	-1.8	-2.4	-2.5
Qualifications: nursing, teaching	4.7	7.3	11.9	-2.6	-3.1	-3.0	-2.1	-0.6	-3.2	-2.7	-3.0	-2.2	-2.2	-3.0	-3.5
Supplements: Fish oil (including cod liver oil)	4.7	6.1	16.0	2.5	2.3	2.3	0.9	1.6	2.7	4.0	2.0	1.1	2.7	2.3	3.4
Vitamin and mineral supplements	4.5	6.0	13.6	-2.8	-2.2	-2.2	-1.2	-2.4	-2.6	-3.4	-2.4	-1.2	-2.0	-2.2	-3.7
Smoking Status	4.3	10.3	22.2	4.7	2.8	2.4	2.1	1.8	3.5	4.4	2.9	1.8	3.5	2.5	4.4
Hayfever/allergic rhinitis (self-reported)	4.2	5.6	10.1	0.4	3.1	3.1	2.9	2.0	2.6	1.1	3.2	1.4	2.2	3.1	1.2
Birth weight of first child	4.1	7.4	10.9	2.0	2.9	2.8	2.1	2.9	3.3	2.9	2.9	1.3	2.8	2.9	3.3
Unable to work because of sickness or disability	4.1	5.3	11.3	3.0	2.2	2.0	1.4	1.3	2.3	2.6	2.2	3.4	2.2	2.0	2.3
Age at First Birth	3.9	5.7	8.6	-2.9	-2.6	-2.1	-1.8	-2.1	-2.5	-2.5	-2.8	-1.4	-2.2	-2.3	-2.9
Major Depression (MDD)	3.8	4.6	6.8	2.1	2.1	1.9	2.0	1.8	2.4	2.5	2.4	1.4	2.1	1.9	2.6
Osteoarthritis (self-reported)	3.8	5.0	9.6	1.7	2.4	2.5	2.1	1.8	2.5	1.5	2.2	3.1	1.8	2.5	2.0
Past tobacco smoking	3.7	6.8	14.2	-3.8	-2.4	-2.2	-1.4	-1.2	-3.0	-3.7	-2.3	-0.7	-2.9	-2.2	-3.4
Smoking status: Current	3.7	5.8	10.6	3.0	1.9	1.7	2.2	2.7	2.5	3.3	2.2	1.6	2.4	1.7	2.9
Hearing aid user	3.7	4.1	6.8	-1.8	-2.4	-2.5	-2.0	-0.4	-2.3	-2.0	-1.8	-1.0	-2.6	-2.5	-1.9
Qualifications: A levels/AS levels or equivalent	3.6	7.9	16.1	-2.6	-3.0	-3.0	-2.3	0.4	-3.1	-3.4	-3.0	-2.2	-2.2	-3.1	-4.0
Frequency of tenseness / restlessness in last 2 weeks	3.5	5.5	8.4	2.6	2.3	2.3	2.4	1.7	2.9	2.6	2.6	1.1	2.1	2.3	2.6
Pain type(s) experienced in last month: Hip pain	3.4	4.3	6.8	2.6	2.5	2.4	2.0	1.9	1.9	0.7	2.6	2.4	1.0	2.4	1.5
Qualifications: College or University degree	3.3	10.3	25.2	-5.0	-2.9	-2.8	-1.7	-0.2	-2.8	-3.6	-3.0	-3.7	-2.1	-2.8	-4.8
Supplements: Glucosamine	3.2	4.1	9.5	1.9	1.8	1.7	1.1	1.6	2.1	2.8	1.7	1.9	2.0	1.8	3.1
Fractured/broken bones in last 5 years	3.2	4.1	7.0	2.4	2.0	2.0	1.4	2.2	2.3	2.3	2.1	0.6	1.4	2.0	2.6
Bipolar Disorder or Schizophrenia	3.0	7.3	12.9	-1.5	-3.0	-3.0	-3.6	-1.4	-3.1	-2.2	-3.1	-2.4	-2.1	-3.0	-3.0
Blood Red Count	3.0	29.0	40.2	-4.6	-6.2	-6.1	-3.9	-4.8	-6.2	-4.8	-6.3	-3.8	-5.3	-6.1	-5.7
Eye problems/disorders: Cataract	3.0	3.5	6.1	-1.7	-1.8	-1.7	-2.5	-1.6	-2.0	-2.2	-1.8	-0.6	-2.0	-1.7	-2.2
Ever smoked	3.0	5.3	10.6	2.8	2.1	1.9	1.6	1.9	2.8	3.3	2.0	0.4	2.6	1.9	3.0
Average weekly beer plus cider intake	3.0	4.3	8.0	2.8	2.3	2.1	2.2	0.8	2.0	1.5	2.5	1.9	1.9	2.1	2.0
Commuting to job workplace: Cycle	3.0	3.7	6.0	-1.2	-2.4	-2.4	-1.2	-0.3	-2.2	-1.9	-2.3	-0.8	-2.2	-2.4	-2.2
Current tobacco smoking	2.9	4.8	8.9	2.6	1.6	1.4	2.0	2.4	2.2	3.0	2.0	1.9	2.2	1.4	2.7
Mouth/teeth dental problems: Mouth ulcers	2.9	4.5	9.2	-2.4	-2.2	-2.1	-0.5	-1.7	-2.3	-2.5	-2.0	-1.3	-2.3	-2.2	-3.0
Age started oral contraceptive pill	2.9	3.6	7.0	-2.0	-1.8	-1.7	-2.6	-1.8	-2.3	-2.1	-1.8	-0.9	-1.7	-1.7	-1.8
Schizophrenia (2018)	2.8	5.7	8.4	-2.0	-2.4	-2.3	-2.6	-1.8	-2.9	-2.4	-2.5	-2.5	-2.1	-2.4	-2.6
Hayfever, allergic rhinitis or eczema	2.8	6.1	11.4	0.5	3.2	3.0	2.9	3.0	2.5	0.5	3.4	1.9	2.1	3.0	1.0
Hypothyroidism/myxoedema (self-reported)	2.6	5.0	9.3	-2.9	-1.9	-1.7	-2.1	-2.4	-2.5	-3.0	-2.1	-1.2	-1.9	-1.7	-2.8
Average weekly spirits intake	2.5	3.1	5.4	2.2	1.7	1.6	2.1	2.1	2.0	1.0	2.1	0.1	0.3	1.6	2.3
Tinnitus: Yes, now most or all of the time	2.5	2.9	5.0	2.2	1.4	1.5	1.0	1.5	1.8	2.2	1.3	1.2	1.9	1.5	2.2
Depression (Nagel 2018)	2.4	3.7	12.0	3.5	1.6	1.3	1.6	1.6	1.8	2.2	1.9	-0.5	1.5	1.3	2.5
Medication: Levothyroxine sodium	2.4	4.1	7.4	-2.7	-1.8	-1.7	-1.7	-1.5	-2.1	-2.4	-2.1	-1.9	-1.7	-1.7	-2.3
Allergy	2.4	5.6	12.0	-1.3	-3.0	-2.8	-2.3	-3.5	-2.5	-0.5	-3.1	-1.8	-1.7	-2.8	-1.1
Illness, injury, bereavement, stress in last 2 years	2.4	2.9	6.6	-2.6	-1.5	-1.6	-1.8	-1.8	-1.8	-1.6	-1.7	-1.6	-1.3	-1.5	-1.7
Allergy or Eczema	2.3	6.2	11.4	0.8	3.2	3.1	2.9	3.4	2.4	0.3	3.3	1.5	1.9	3.1	0.9
Alcohol usually taken with meals	2.3	3.8	6.2	-2.5	-2.2	-2.2	-2.4	-0.6	-2.0	-1.6	-1.9	-1.4	-1.5	-2.2	-1.9
Qualifications: None of the above	2.3	5.0	10.3	3.2	2.1	2.2	2.0	0.3	2.3	2.7	1.9	1.7	1.6	2.1	3.2
Heart attack	2.3	2.9	9.3	3.0	1.7	1.6	0.6	-0.2	1.7	1.9	1.8	0.9	1.7	1.6	1.8
Length of working week for main job	2.3	2.6	6.2	1.9	1.6	1.5	0.6	1.0	2.0	2.1	1.5	0.6	2.5	1.5	1.3
Hearing difficulty/problems with background noise	2.2	3.6	8.8	2.9	1.1	1.0	0.5	3.0	1.7	2.4	1.0	2.5	1.4	1.1	2.1
Mineral and other dietary supplements	2.2	2.9	9.7	-1.7	-1.3	-1.4	-0.1	-1.3	-1.9	-3.1	-1.0	-0.7	-1.4	-1.4	-2.7
Average weekly fortified wine intake	2.1	2.4	4.4	-0.5	1.7	1.7	2.1	1.9	1.4	1.0	1.8	1.9	1.5	1.6	0.8
Financial difficulties in last 2 years	2.1	2.8	9.6	3.1	1.6	1.6	1.1	1.5	1.8	1.2	1.9	1.1	0.6	1.5	1.8
Loud music exposure frequency	2.1	2.3	5.6	2.3	1.2	1.0	0.5	-0.1	1.6	2.4	1.7	0.8	1.8	0.9	2.1
Smoking status: Previous	2.1	3.2	8.8	3.0	1.6	1.4	0.5	-0.1	2.0	2.5	1.5	0.6	1.9	1.4	2.4
Financial situation satisfaction	2.1	2.6	8.0	2.8	1.3	1.1	1.2	1.8	1.6	1.8	1.7	0.4	1.0	1.0	2.1
Heart attack/myocardial infarction (self-reported)	2.1	2.7	9.6	3.1	1.6	1.6	0.5	-0.0	1.7	1.9	1.6	0.9	1.5	1.5	1.8
Pain all over the body in last month	2.0	2.1	3.5	1.0	1.6	1.4	1.8	0.4	1.5	1.5	1.7	1.3	1.9	1.4	1.3
Wheeze or whistling in the chest in last year	2.0	3.6	8.6	2.1	1.7	1.6	1.3	2.9	1.9	1.8	2.0	1.6	1.2	1.6	2.4
Family relationship satisfaction	2.0	2.4	4.7	0.2	-1.6	-1.7	-1.5	0.6	-1.5	-2.0	-0.9	-1.7	-2.2	-1.7	-1.9
Miserableness	2.0	3.5	6.5	1.8	1.9	1.9	2.6	1.3	2.2	2.0	2.0	0.2	1.8	1.9	2.1
Schizophrenia (2014)	1.9	4.2	6.8	-1.0	-2.1	-2.1	-2.5	-0.1	-2.5	-2.2	-2.2	-2.1	-1.7	-2.1	-2.6
Frequency of depressed mood in last 2 weeks	1.9	2.7	5.5	2.1	1.5	1.3	2.2	2.3	1.8	1.5	1.7	-0.3	1.0	1.3	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.0	9.5	3.1	1.5	1.2	1.3	2.5	1.9	1.7	1.8	-0.6	1.3	1.3	1.2
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	7.4	-2.2	-1.4	-1.5	-0.3	-0.7	-1.7	-2.2	-1.5	-2.7	-1.1	-1.5	-2.3
Neuroticism (2016)	1.8	2.5	4.8	1.7	1.6	1.4	2.2	2.1	1.4	0.4	1.9	2.1	0.6	1.4	1.0
Blood White Count	1.8	13.1	21.5	4.3	4.3	4.0	3.7	2.5	4.0	2.0	4.6	3.0	2.7	4.1	3.0
Alcohol intake frequency.	1.8	4.1	7.5	-0.0	-2.5	-2.4	-1.4	-1.4	-2.5	-1.8	-2.6	0.4	-2.7	-2.4	-1.9
Ulcerative Colitis (UC)	1.7	3.2	7.7	-0.2	2.0	1.9	2.8	1.1	1.9	1.2	1.9	2.2	1.9	1.9	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	9.3	3.1	1.1	0.9	0.8	0.7	1.5	1.9	1.5	-0.5	1.0	0.9	2.0
Medication: Ventolin 100micrograms inhaler	1.7	2.2	8.9	-0.1	1.5	1.4	1.1	3.0	1.3	0.5	1.2	2.2	1.4	1.4	0.4
Rheumatoid Arthritis	1.6	2.3	4.1	1.1	2.0	2.0	1.4	1.2	1.7	1.1	1.3	0.0	1.8	2.0	1.0
Medication: Atenolol	1.6	2.0	11.3	3.4	0.2	0.1	0.1	-0.3	0.8	2.5	0.4	-0.2	0.6	0.1	2.2
Neuroticism score	1.6	3.3	7.8	2.2	1.9	1.8	2.8	1.7	1.8	1.4	2.0	0.7	1.3	1.8	1.6
Tense / ‘highly strung’	1.6	2.6	4.9	-1.6	-1.8	-1.9	-0.5	-1.2	-2.0	-1.9	-1.3	-1.0	-2.2	-1.9	-1.4
Medication: Lisinopril	1.6	2.0	5.0	0.1	-1.6	-1.6	-0.4	-1.6	-1.8	-1.4	-1.2	-1.3	-2.2	-1.6	-0.7
Intelligence (Savage-Jansen 2018)	1.5	4.7	8.9	-1.5	-1.9	-1.9	-1.7	-0.1	-2.2	-3.0	-1.7	-3.0	-2.5	-1.8	-3.0
Alzheimer’s Disease (including proxy)	1.5	2.1	3.8	0.7	1.4	1.6	1.9	0.8	1.9	1.9	1.5	0.1	1.5	1.5	1.6
Body Mass Index (BMI) (2010)	1.5	2.0	4.6	1.9	1.2	1.1	1.1	0.7	1.2	1.8	1.0	0.9	1.8	1.1	2.1
Mean Putamen Volume	1.5	1.8	3.2	1.0	1.7	1.6	1.8	0.5	1.5	0.8	1.7	0.0	1.2	1.6	1.2
Mouth/teeth dental problems: Dentures	1.5	2.4	5.7	2.4	1.6	1.5	0.1	0.4	1.4	1.7	1.6	1.7	1.3	1.4	2.2
Peak expiratory flow (PEF)	1.5	3.6	11.6	3.4	1.8	1.6	1.4	0.8	1.8	2.4	1.5	0.1	2.1	1.6	2.0
Comparative body size at age 10	1.5	4.1	5.8	1.6	2.2	2.0	2.0	1.5	2.4	2.3	2.0	-1.7	2.2	2.1	2.2
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.9	4.4	1.8	1.4	1.2	1.4	0.2	1.4	1.2	1.3	1.4	0.8	1.3	2.1
Bipolar Disorder (2018)	1.4	2.2	6.4	0.2	-1.8	-1.9	-2.5	0.0	-1.4	-0.6	-1.8	-0.8	-0.7	-1.9	-1.6
Heel T-Score	1.4	11.3	18.2	-3.3	-3.5	-3.9	-2.6	-3.2	-4.3	-3.6	-3.1	-0.5	-2.5	-3.8	-4.1
Fed-up feelings	1.4	2.6	7.9	2.8	1.3	1.3	2.2	1.3	1.6	1.4	1.4	-0.1	0.9	1.3	2.0
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.3	2.1	1.2	1.1	0.4	0.2	1.5	1.9	1.1	0.5	1.1	1.1	1.7
Medication: Amlodipine	1.4	2.0	6.0	2.4	1.2	0.9	1.0	-1.3	1.1	1.5	1.8	-1.3	0.7	1.0	2.0
Friendships satisfaction	1.4	1.8	2.9	-0.4	-1.5	-1.5	-1.2	-0.3	-1.3	-1.7	-1.2	-1.7	-1.3	-1.4	-1.7
Impedance of whole body	1.4	7.0	11.2	-2.7	-3.0	-2.9	-2.3	-0.9	-3.2	-2.7	-2.8	-0.7	-2.7	-2.9	-3.4
Lung FEV1/FVC ratio	1.3	6.7	22.9	4.8	1.0	0.8	0.2	0.1	2.0	4.7	0.9	1.4	2.3	0.8	4.5
Father’s age at death	1.3	1.8	6.3	-2.5	-1.3	-1.1	-0.4	0.7	-0.9	-1.1	-1.4	-2.0	-0.7	-1.1	-1.1
Headache pain in last month	1.3	2.2	3.4	-1.3	-1.8	-1.8	-1.4	0.2	-1.6	-1.5	-1.5	-0.9	-1.7	-1.8	-1.7
Neck or shoulder pain in last month	1.3	1.8	3.7	1.1	1.4	1.3	0.1	0.3	1.5	1.7	1.9	1.4	1.0	1.3	1.9
Supplements: Vitamin C	1.3	1.5	4.4	2.1	0.6	0.6	-0.5	1.6	0.8	1.6	0.7	-1.3	0.3	0.6	2.1
Illnesses of siblings: Diabetes	1.3	1.6	2.7	1.6	1.3	1.3	0.4	0.5	1.4	1.6	1.3	1.5	0.9	1.4	1.3
Hypothyroidism (self reported)	1.2	2.9	7.7	-2.8	-1.1	-1.0	-1.7	-1.5	-1.6	-2.4	-1.6	-0.7	-1.4	-0.9	-2.2
Maternal smoking around birth	1.2	1.7	5.3	2.3	1.0	0.9	1.1	-0.1	1.3	1.6	1.0	1.8	0.4	0.9	1.7
Medication: Simvastatin	1.2	1.8	5.7	2.4	-0.7	-0.8	-2.0	-2.4	-0.9	0.6	-0.8	0.5	-1.4	-0.7	0.7
Time employed in main current job	1.2	1.4	1.9	-0.2	1.3	1.3	1.0	0.9	1.3	1.0	1.4	1.3	1.3	1.3	1.2
Exposure to tobacco smoke outside home	1.2	1.6	4.7	2.2	1.0	0.9	1.8	0.6	1.1	1.5	1.4	0.2	0.4	0.9	1.6
Medication for pain relief, constipation, heartburn	1.2	2.0	6.7	-2.6	-0.9	-0.7	-0.5	-1.2	-1.4	-2.4	-0.8	-0.3	-1.1	-0.8	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	5.2	-1.0	-0.9	-0.8	-1.5	-1.1	-0.9	-0.9	-0.8	-2.3	-0.7	-0.8	-0.6
Osteoporosis (self-reported)	1.2	1.5	3.2	0.6	1.7	1.7	1.1	1.6	1.4	0.2	1.7	0.1	0.5	1.8	0.5
Angina	1.1	1.4	6.4	2.5	0.9	0.9	0.1	-1.1	1.0	1.2	1.0	0.6	0.2	0.9	1.6
Impedance of leg (right)	1.1	5.3	8.7	-2.0	-2.8	-2.7	-2.1	-1.8	-3.0	-1.6	-2.6	-0.9	-2.1	-2.7	-2.2
Eye problems/disorders: None of the above	1.1	1.2	3.4	1.4	1.1	1.1	1.9	-0.3	1.0	1.0	1.0	-0.6	0.8	1.1	1.4
Medication: Aspirin	1.1	1.4	5.0	1.1	0.9	1.0	1.0	0.0	1.3	2.2	1.1	0.3	1.4	1.0	1.5
Commuting to job workplace: Walk	1.1	1.2	2.7	0.5	1.5	1.6	1.6	0.0	0.9	0.0	1.3	0.9	0.5	1.6	-0.1
Diabetes (father)	1.0	1.3	2.6	0.2	-1.3	-1.4	-1.0	-1.6	-1.5	-0.4	-1.4	0.1	-0.8	-1.4	-1.2
Pulse wave Arterial Stiffness index	1.0	1.2	3.0	-0.2	-1.4	-1.4	-0.8	-0.1	-1.0	-0.5	-1.7	-0.8	-0.8	-1.3	-1.6
Impedance of arm (left)	1.0	4.6	10.7	-2.6	-2.1	-2.1	-1.8	-0.1	-2.4	-2.6	-2.0	-0.5	-2.2	-2.1	-3.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.6	-0.0	1.2	1.2	1.6	0.7	1.6	1.4	1.4	1.0	1.6	1.2	0.9
Number of children fathered	1.0	1.2	4.9	1.2	0.9	1.0	0.1	2.2	1.1	0.4	0.8	1.0	0.8	1.0	1.1
Medication: Seretide 50 evohaler	1.0	1.2	2.1	-0.5	-1.0	-1.0	-1.4	1.2	-1.1	-1.2	-1.3	0.1	-1.0	-1.1	-1.4
High cholesterol (Self-reported)	1.0	1.8	6.9	2.6	0.5	0.6	-1.0	-1.8	0.6	1.9	0.6	1.1	-0.1	0.6	2.2
Medication: Atorvastatin	1.0	1.3	2.1	1.2	0.9	1.0	1.0	1.0	1.4	1.4	1.2	0.8	1.2	1.0	1.3
Bipolar Disorder (2011)	0.9	0.8	3.5	1.4	-0.8	-1.0	-1.9	-0.0	-0.6	0.3	-0.8	-0.7	0.0	-1.1	-0.2
Fasting Glucose	0.9	1.1	2.0	0.8	1.3	1.1	1.4	-0.3	1.1	0.8	1.3	1.1	0.8	1.1	1.0
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.1	-1.0	-1.1	-1.3	-0.5	-1.0	-1.4	-0.8	-1.2	-0.8	-0.8	-1.3	-0.8
Had other major operations	0.9	1.1	2.2	-0.5	-1.4	-1.2	-0.1	0.7	-1.2	-1.1	-1.5	-0.6	-1.4	-1.2	-0.9
Diabetes (self-reported)	0.9	1.4	6.6	2.6	0.7	0.6	0.6	-0.6	0.6	1.4	1.1	1.1	0.3	0.6	1.8
Impedance of arm (right)	0.9	4.1	10.4	-2.2	-2.0	-2.0	-1.5	0.2	-2.4	-2.5	-1.7	0.4	-2.1	-2.0	-3.2
Happiness	0.9	1.1	2.4	-0.3	-1.0	-0.9	-0.8	1.1	-0.7	-1.3	-0.6	-1.6	-1.4	-0.9	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.5	-0.5	-1.2	-1.2	-0.8	-1.6	-1.1	-0.8	-1.1	-0.9	-1.3	-1.2	-1.1
Pulse wave peak to peak time	0.9	1.1	2.6	0.4	1.3	1.2	0.9	0.1	0.9	0.6	1.6	0.7	0.8	1.2	1.6
Migraine (self-reported)	0.9	1.1	2.4	-1.1	-1.0	-1.0	-0.5	-0.5	-1.2	-1.5	-0.7	-1.2	-0.8	-1.0	-1.6
Medication: Aspirin	0.9	1.2	3.3	1.4	0.9	0.9	0.6	0.2	1.2	1.8	1.2	0.4	1.2	1.0	1.3
Cholesterol lowering medication	0.9	1.4	5.7	2.4	0.6	0.6	-0.3	-1.5	0.5	1.2	0.2	1.5	-0.4	0.7	1.7
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.8	0.6	0.9	1.1	0.7	0.7	1.2	1.5	0.7	1.1	0.5	1.1	1.7
Pack years of smoking	0.9	1.3	3.6	1.9	1.0	0.9	0.8	0.8	1.3	1.7	0.6	1.1	1.0	1.0	1.1
Reaction Time	0.8	1.4	2.1	0.3	1.4	1.4	1.3	0.5	1.2	1.1	1.3	1.5	1.1	1.3	1.4
HDL Cholesterol	0.8	1.4	3.9	-1.7	0.7	1.0	1.4	1.5	-0.1	-2.0	1.0	0.6	-1.0	0.8	-1.1
Type 2 Diabetes (T2D) (2018)	0.8	1.5	7.6	2.8	0.9	0.7	0.9	1.0	0.7	1.4	1.0	0.6	0.2	0.7	1.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.8	1.9	1.0	0.9	1.0	-0.7	0.3	-0.0	1.2	0.6	0.2	0.9	0.5
Impedance of leg (left)	0.8	3.9	7.2	-1.6	-2.4	-2.4	-1.8	-1.2	-2.7	-1.6	-2.2	-0.2	-1.8	-2.4	-2.1
Pulse rate	0.8	1.4	4.6	2.0	-0.0	0.1	0.3	2.1	1.0	1.8	0.3	-0.3	0.1	0.1	2.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	7.0	-0.2	0.8	1.0	2.6	0.9	0.5	0.2	0.6	-0.2	0.7	1.0	0.1
Chronic bronchitis/emphysema (mother)	0.8	0.9	3.3	0.9	1.1	0.9	1.3	0.3	0.7	0.1	1.1	1.8	0.5	0.9	0.1
Shortness of breath walking on level ground	0.8	0.9	3.2	1.7	0.0	0.0	-0.1	0.6	0.5	1.5	-0.1	1.8	0.8	0.0	1.2
Medication: Ibuprofen	0.8	0.9	1.8	-0.5	-1.1	-1.1	-1.1	0.8	-0.9	-0.9	-0.9	-1.3	-1.0	-1.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.4	0.8	-1.6	-1.8	-1.0	0.9	-1.6	-1.0	-1.0	-0.9	-1.5	-1.9	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	6.2	2.5	-0.3	-0.5	0.1	-1.1	-0.3	0.6	-0.3	-1.2	-0.6	-0.5	0.5
Schizophrenia vs Biploar Disorder	0.7	0.9	4.1	-0.8	0.3	0.2	0.6	-0.5	-0.6	-2.0	0.3	-1.3	-1.2	0.2	-1.3
Verbal and Numeric Reasoning (VNR)	0.7	1.8	6.6	-1.1	-1.0	-1.0	-0.7	0.3	-1.2	-1.6	-1.0	-2.6	-0.9	-1.0	-2.0
Neuroticism	0.7	1.6	4.4	2.0	1.2	1.1	2.1	1.5	0.9	0.8	1.4	0.1	0.2	1.1	1.2
Medication: Metformin	0.7	1.0	5.2	2.3	0.5	0.5	1.0	0.0	0.4	1.3	0.6	-1.0	0.3	0.5	1.4
Pack years adult smoking proportion	0.7	1.1	3.7	1.9	0.9	0.9	0.9	0.7	1.2	1.4	0.6	0.9	0.9	0.9	0.9
Medication: Cholesterol lowering	0.7	1.1	3.6	1.9	-0.4	-0.6	-1.4	-1.9	-0.1	1.5	-0.1	0.1	0.1	-0.6	0.9
Ever highly irritable/argumentative for 2 days	0.7	0.8	4.2	2.1	-0.5	-0.7	-0.9	-0.4	0.3	1.4	-0.1	-0.5	0.6	-0.7	0.9
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	4.5	-2.1	0.5	0.7	1.2	1.6	0.0	-1.8	0.2	0.3	-0.2	0.7	-1.0
Glaucoma (self-reported)	0.7	0.8	4.1	2.0	-0.3	-0.6	-0.6	1.7	0.1	0.8	0.0	0.2	-0.3	-0.6	0.9
Medication: Blood pressure	0.7	1.2	7.5	2.7	-0.0	-0.3	-0.1	-1.3	0.1	1.4	0.3	-1.0	0.1	-0.3	1.2
Angina (self-reported)	0.7	1.0	5.4	2.3	0.7	0.7	-0.1	-1.3	0.6	0.8	0.8	0.6	-0.2	0.7	1.1
Heart disease (mother)	0.7	0.9	3.2	1.8	0.9	0.9	0.6	-0.6	0.8	0.9	1.0	-0.1	-0.1	0.9	1.4
Knee pain experienced in last month	0.7	1.1	4.9	2.2	1.0	0.8	-0.1	-0.1	1.1	0.7	1.3	1.0	-0.0	0.8	1.2
Leg fat-free mass (right)	0.7	3.9	8.4	2.9	2.0	1.9	1.9	0.6	2.2	2.1	1.9	0.3	1.6	1.9	2.7
Leg predicted mass (right)	0.7	3.9	8.4	2.9	2.0	1.9	1.9	0.7	2.3	2.1	1.9	0.3	1.6	1.9	2.7
Ever taken oral contraceptive pill	0.7	0.8	1.9	0.2	0.8	0.9	0.6	-0.3	1.2	0.9	0.8	1.2	0.9	0.9	1.4
Myopia	0.7	0.9	2.6	0.8	1.2	0.9	1.4	0.7	0.7	-0.3	1.6	0.9	-0.5	1.0	0.6
Vascular/heart problems diagnosed by doctor	0.7	1.9	12.5	-3.5	0.3	0.5	0.2	1.8	-0.0	-1.5	0.1	1.0	0.8	0.5	-1.5
Supplements: Calcium	0.7	0.7	3.8	1.1	-0.6	-0.5	-2.0	0.4	-0.2	0.3	-0.2	-1.2	-0.9	-0.5	0.7
Coronary Artery Disease (CAD)	0.6	0.7	4.6	2.1	0.2	0.1	-0.1	-0.2	0.6	0.8	0.6	0.7	0.0	0.1	1.2
Sensitivity / hurt feelings	0.6	1.1	3.9	0.8	0.8	0.7	2.0	1.2	1.1	1.3	0.8	0.0	0.6	0.7	1.2
Relative age of first facial hair	0.6	1.2	1.8	-1.4	-1.3	-1.2	-0.9	1.0	-1.0	-0.9	-1.4	-1.1	-0.6	-1.2	-0.9
Severe depression (siblings)	0.6	0.6	1.8	-0.5	-1.1	-1.1	-0.6	-0.3	-0.9	-0.3	-1.3	-0.4	-0.5	-1.1	-0.6
Leg fat-free mass (left)	0.6	3.4	7.8	2.8	1.7	1.6	1.7	0.3	2.1	2.3	1.6	-0.3	1.5	1.6	2.7
High blood pressure	0.6	1.7	11.2	3.3	-0.3	-0.6	0.2	-1.4	0.1	1.7	-0.1	-1.0	-0.4	-0.5	1.4
Leg predicted mass (left)	0.6	3.2	7.6	2.8	1.6	1.6	1.6	0.2	2.0	2.2	1.6	-0.2	1.4	1.6	2.6
Hair/balding pattern: Pattern 2	0.6	0.8	1.6	-0.4	1.1	1.0	0.7	0.4	1.0	0.6	0.8	1.2	1.3	1.0	0.3
Trunk fat-free mass	0.6	3.4	10.7	3.3	1.5	1.4	1.1	-0.1	1.8	2.5	1.4	-0.0	1.6	1.4	2.9
Worrier / anxious feelings	0.6	1.1	4.1	0.9	1.0	0.9	1.2	0.9	0.7	0.4	1.3	2.0	0.6	0.9	0.6
Prospective memory result	0.6	0.7	2.8	0.6	0.7	0.8	0.8	-0.3	0.7	0.9	0.7	0.8	0.6	0.7	1.7
Arm fat-free mass (right)	0.6	3.1	10.0	2.9	1.2	1.2	1.0	-0.8	1.6	2.6	1.0	-0.5	1.4	1.2	3.2
Number of full brothers	0.6	0.8	2.1	0.5	0.4	0.4	0.5	1.2	0.8	1.4	0.2	1.4	0.9	0.4	1.0
Arm predicted mass (right)	0.6	2.9	9.2	2.8	1.2	1.2	1.0	-0.7	1.6	2.5	1.1	-0.4	1.4	1.2	3.0
Pulse rate, automated reading	0.6	2.0	7.4	2.1	-0.6	-0.4	-0.2	0.6	0.7	2.7	-0.6	-1.5	0.6	-0.4	2.7
Number of full sisters	0.6	0.7	3.0	0.8	0.3	0.6	0.1	1.7	0.5	0.6	0.5	1.4	0.2	0.5	1.2
Hypertension (Self-reported)	0.6	1.6	10.0	3.2	-0.5	-0.9	0.0	-1.5	-0.1	1.6	-0.3	-1.0	-0.6	-0.8	1.3
Whole body fat-free mass	0.6	3.6	10.6	3.2	1.6	1.5	1.3	0.0	2.0	2.5	1.5	-0.0	1.6	1.5	3.0
Loneliness, isolation	0.6	0.8	1.6	-0.7	-1.1	-1.1	-0.0	-0.0	-0.9	-0.9	-1.2	0.1	-0.8	-1.0	-1.2
Diabetes diagnosed by doctor	0.6	1.0	6.1	2.5	0.4	0.3	0.5	-1.0	0.2	1.1	0.6	0.7	0.0	0.2	1.5
Medication for cholesterol	0.6	0.9	6.2	-1.7	0.0	0.1	-0.2	2.5	0.2	-0.3	0.2	-0.0	1.0	0.1	-0.8
Back pain experienced in last month	0.6	0.9	3.4	1.9	1.2	1.0	0.2	0.5	0.8	0.6	1.1	-0.6	0.7	1.1	0.6
Breast cancer (self-reported)	0.6	0.8	2.2	-1.5	-0.5	-0.3	-0.0	-0.5	-0.7	-1.4	-0.7	1.2	-0.7	-0.4	-1.1
Illnesses of father: None of the above (group 1)	0.6	0.7	3.0	-1.5	-0.6	-0.6	-1.2	0.5	-0.2	-0.0	-0.8	-1.7	0.2	-0.7	-0.2
Whole body water mass	0.6	3.5	10.2	3.2	1.6	1.5	1.3	-0.0	1.9	2.5	1.5	-0.0	1.5	1.5	2.9
Guilty feelings	0.6	0.8	3.6	1.4	-0.9	-1.0	-0.3	-0.3	-0.5	0.3	-0.9	-1.9	-0.6	-1.0	0.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.9	1.4	-0.7	-0.8	-1.1	1.2	0.1	1.2	-0.5	-0.2	-0.1	-0.8	0.8
Basal metabolic rate	0.6	3.3	9.9	3.1	1.5	1.4	1.4	-0.1	1.9	2.4	1.3	-0.1	1.4	1.4	2.9
Heart disease (siblings)	0.6	0.7	2.1	1.4	-0.8	-0.7	-1.0	-1.2	-0.7	0.4	-0.9	-0.3	-1.0	-0.7	0.1
Alcohol drinker status: Previous	0.6	0.6	1.8	0.3	-0.9	-1.1	-0.3	-0.6	-1.0	-0.4	-0.7	0.0	-1.3	-1.0	-0.7
Arm predicted mass (left)	0.6	3.3	10.0	3.2	1.3	1.2	1.1	-0.3	1.7	2.7	1.2	-0.1	1.5	1.2	3.1
Triglycerides	0.5	0.8	2.7	0.8	-0.8	-1.0	-1.0	-1.6	-0.3	1.4	-0.8	-0.6	0.2	-0.8	0.6
Cardiovascular Disease	0.5	1.8	11.2	3.3	0.3	-0.1	0.0	-0.9	0.5	2.0	0.4	1.1	-0.2	0.1	2.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.9	1.0	0.9	0.8	0.3	0.1	0.9	0.5	1.4	1.1	0.6	0.8	0.8
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.3	0.1	0.6	0.6	1.1	0.6	0.7	1.1	0.5	1.1	0.1	0.6	1.1
Medication: Co-codamol	0.5	0.6	3.1	1.1	-0.1	-0.1	-0.1	1.8	0.3	0.3	0.1	1.3	-0.5	-0.1	0.8
Townsend deprivation index at recruitment	0.5	0.7	3.4	1.2	0.6	0.4	1.1	-0.4	0.3	0.4	0.7	1.8	-0.1	0.4	0.7
Qualifications: CSEs or equivalent	0.5	0.7	2.9	1.1	0.8	0.8	1.7	0.0	0.4	-0.9	1.1	0.3	-0.5	0.8	0.4
Trunk predicted mass	0.5	3.0	10.1	3.2	1.3	1.2	0.9	-0.2	1.6	2.4	1.3	-0.2	1.5	1.3	2.7
Exposure to tobacco smoke at home	0.5	0.6	1.7	1.3	-0.3	-0.5	-0.7	-1.0	-0.6	-0.4	-0.2	1.2	-1.1	-0.4	-0.2
Breastfed as a baby	0.5	0.6	1.5	0.8	0.9	0.9	0.2	1.2	0.9	0.4	1.0	0.2	0.5	0.8	0.5
Worry too long after embarrassment	0.5	0.9	2.8	1.6	1.0	0.8	1.7	0.6	0.5	0.4	1.2	0.3	-0.2	0.9	0.8
Age at first live birth	0.5	0.8	4.1	-0.8	-0.4	-0.5	-0.6	-1.0	-0.8	-0.9	-0.3	-2.0	0.2	-0.5	-1.2
Emphysema/chronic bronchitis	0.5	0.5	3.5	0.6	0.4	0.3	0.0	1.9	0.8	0.8	0.4	-0.1	0.3	0.3	0.8
Mean time to correctly identify matches	0.5	0.9	1.3	-0.5	0.9	1.0	1.0	0.5	1.0	1.2	0.9	1.0	1.0	1.0	1.1
Asthma (self-reported)	0.5	0.9	4.9	0.3	1.1	0.9	0.7	2.2	0.5	-0.8	0.9	0.9	0.4	0.9	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.8	0.0	1.2	1.1	0.8	1.3	0.9	0.8	1.0	-0.3	1.7	1.2	0.5
Mother’s age at death	0.5	0.6	2.4	-0.9	-0.7	-0.7	-1.6	-0.0	-0.4	0.2	-0.6	-1.1	0.4	-0.8	-0.4
Risk taking	0.5	0.8	4.5	2.1	0.5	0.3	-0.2	0.1	0.6	1.3	0.7	-0.7	0.4	0.2	1.0
Basal cell carcinoma (self-reported)	0.5	0.6	6.4	-0.2	0.2	0.3	0.2	2.5	0.6	0.1	0.7	0.2	0.1	0.3	0.2
Breast Cancer	0.4	1.0	2.1	0.6	-1.3	-1.3	-1.4	-0.4	-1.2	-0.1	-1.3	-0.4	-1.2	-1.3	0.4
Lupus	0.4	0.6	1.9	-1.4	-0.8	-0.7	-0.4	-1.2	-0.7	-0.5	-1.2	-0.0	-0.1	-0.7	-0.5
Respiratory disease	0.4	0.9	3.7	0.6	1.0	0.9	0.4	1.9	0.2	-1.5	1.0	-0.0	-0.0	0.9	-0.4
Chronotype (morning person)	0.4	0.9	3.6	-0.2	-0.6	-0.7	0.2	-1.0	-1.0	-1.9	-0.4	-1.3	-0.8	-0.7	-1.3
Number of treatments/medications taken	0.4	0.7	3.2	1.8	0.1	-0.1	-0.5	-1.0	0.3	1.3	-0.0	-0.3	-0.3	-0.1	1.4
Medication for hormone replacement therapy	0.4	0.5	2.0	-0.1	0.7	0.5	1.4	-1.1	0.4	0.4	0.7	0.5	0.6	0.5	0.0
Supplements: Zinc	0.4	0.5	1.0	-0.2	-0.9	-1.0	-0.6	-0.5	-0.2	0.8	-0.7	0.5	-0.7	-0.9	0.6
Diabetes (mother)	0.4	0.6	2.2	1.5	0.6	0.5	0.4	0.2	0.8	1.0	0.4	-0.8	0.7	0.5	0.7
Relative age voice broke	0.4	0.7	1.3	-1.1	-0.9	-0.8	-0.6	0.5	-0.8	-1.1	-1.0	-0.3	-0.5	-0.8	-0.9
Taking other prescription medications	0.4	0.6	2.8	0.1	0.6	0.5	0.2	-0.3	0.6	1.0	0.5	1.5	0.1	0.5	1.7
Age when periods started (menarche)	0.4	0.8	1.5	-1.2	-0.9	-0.8	-1.2	-1.2	-1.0	-0.7	-0.9	-0.8	-0.4	-0.8	-0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.9	1.1	0.1	-0.0	-0.1	1.0	0.7	1.4	-0.2	0.7	0.6	0.0	0.7
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	-0.3	-0.4	-0.6	0.2	-1.5	-0.8	-0.7	-0.0	-0.2	-0.5	-0.6	-1.1
High blood pressure (mother)	0.4	0.5	2.1	1.4	0.4	0.3	0.8	0.2	0.7	0.9	0.5	-1.0	0.4	0.2	0.4
Fluid intelligence score	0.4	0.9	3.4	-0.1	-0.0	-0.1	0.3	1.0	-0.6	-1.6	0.2	-1.8	-0.5	-0.1	-1.8
Number of live births	0.4	0.5	3.2	1.2	0.3	0.3	-0.6	0.0	0.4	0.8	-0.1	-1.8	0.2	0.3	0.4
Depression (self-reported)	0.4	0.5	1.3	0.1	-1.0	-1.2	-0.2	-0.1	-0.7	-0.2	-0.8	-0.7	-0.8	-1.1	-0.5
Lung cancer (father)	0.4	0.5	1.8	0.9	0.4	0.5	0.1	1.3	0.6	-0.2	0.6	-1.3	-0.4	0.5	0.4
Illnesses of mother	0.4	0.5	3.5	-1.9	-0.0	0.2	0.0	-0.2	-0.3	-1.1	-0.2	0.5	-0.2	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.5	2.1	0.9	0.6	0.6	0.3	0.8	1.7	0.9	-0.7	1.6	0.7	1.4
Birth weight	0.4	0.9	3.9	2.0	0.8	0.7	0.0	0.7	0.8	1.0	0.9	-0.4	0.7	0.8	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.5	1.3	0.4	0.2	0.0	-1.9	0.1	0.6	0.6	0.3	0.0	0.2	0.2
Medication: Omeprazole	0.4	0.5	2.4	0.3	0.4	0.6	0.5	0.4	0.8	1.2	0.4	0.5	-0.0	0.6	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.4	0.2	-0.0	-0.1	-0.6	1.8	-0.1	-0.6	-0.3	-0.7	0.1	-0.1	-0.9
Suffer from ‘nerves’	0.4	0.6	1.7	1.0	1.0	0.7	1.3	-0.4	0.2	0.1	1.2	0.4	-0.0	0.8	0.8
Overall health rating	0.4	0.9	6.5	2.5	0.6	0.4	0.1	0.5	0.7	0.8	0.7	0.4	-0.3	0.4	1.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.6	1.3	0.4	0.4	0.8	0.4	0.3	0.5	0.7	-1.2	0.6	0.4	0.2
Long-standing illness, disability or infirmity	0.4	0.6	3.2	1.8	0.7	0.5	-0.0	0.1	0.6	0.8	0.9	0.5	0.1	0.5	1.0
Average weekly champagne plus white wine intake	0.4	0.6	2.5	-1.6	-0.3	-0.6	0.3	0.3	-0.7	-1.1	-0.2	0.5	0.1	-0.6	-1.2
Commuting to job workplace: Public transport	0.4	0.5	2.7	-1.6	-0.4	-0.3	0.9	-0.5	-0.2	-0.8	-0.6	0.2	-0.9	-0.3	-0.7
Medication: Blood pressure	0.4	0.7	1.8	1.3	-0.8	-0.8	-0.2	-1.3	-0.4	0.1	-0.7	-0.1	-1.3	-0.8	0.6
Arm fat-free mass (left)	0.4	2.2	8.2	2.9	0.9	0.9	0.7	-0.4	1.3	2.3	0.8	-0.4	1.0	0.9	2.7
Irritability	0.4	0.7	1.9	-0.3	-1.0	-0.9	0.2	0.4	-0.9	-1.1	-1.4	-0.4	-0.7	-0.8	-1.1
Leg fat mass (left)	0.4	1.6	4.4	1.8	0.9	0.9	1.3	-0.8	1.5	1.9	0.5	-0.1	0.9	1.0	2.1
Irritable Bowel Disease (IBD)	0.3	0.8	4.4	-0.4	0.6	0.7	1.5	0.7	0.6	0.3	0.4	2.1	0.6	0.6	0.1
Ovarian Cancer	0.3	0.3	2.5	0.9	-0.2	-0.1	-0.2	-1.6	-0.0	0.7	-0.2	-0.2	-0.1	-0.1	0.0
Height	0.3	4.9	30.1	5.5	1.0	0.7	-0.4	1.4	1.1	3.1	1.1	-0.3	1.3	0.8	3.2
Waist Hip Ratio (WHR)	0.3	1.3	3.9	0.6	-1.3	-1.2	-0.6	0.6	-0.9	-1.0	-1.2	-1.2	-2.0	-1.2	-1.1
Hand grip strength (left)	0.3	0.8	2.5	-1.6	-1.0	-0.8	-0.6	-0.3	-0.4	-0.3	-1.2	-1.6	0.2	-0.8	-0.5
Hearing difficulty/problems: Yes	0.3	0.4	1.0	-0.1	-0.8	-0.6	-1.0	0.6	-0.6	-0.1	-0.8	0.9	-0.7	-0.6	-0.1
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	-0.5	-0.3	-0.1	-0.2	-1.1	-0.5	-0.7	-0.3	-0.8	-0.7	-0.2	-0.0
Hand grip strength (right)	0.3	0.9	4.6	-2.1	-0.8	-0.5	-0.0	0.1	-0.4	-0.8	-1.4	-1.0	-0.1	-0.5	-0.9
Body mass index (BMI)	0.3	1.4	3.3	1.3	1.0	1.1	1.2	-0.7	1.6	1.5	0.5	0.1	0.8	1.1	1.8
Had menopause	0.3	0.4	1.2	-0.2	-0.6	-0.6	-1.1	-0.0	-0.4	0.4	-0.6	1.1	-0.6	-0.7	0.3
Medication: Ramipril	0.3	0.4	0.8	0.9	-0.6	-0.7	-0.8	-0.5	-0.5	-0.1	-0.8	0.4	-0.7	-0.7	-0.6
Weight	0.3	1.6	4.9	2.2	0.8	0.8	1.0	-0.3	1.4	1.9	0.5	-0.3	0.8	0.8	2.2
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.5	1.9	0.8	0.5	0.5	0.3	0.6	1.2	0.7	-1.2	1.5	0.6	0.8
Asthma	0.3	0.7	4.0	0.3	0.7	0.5	0.4	2.0	0.1	-1.1	0.6	0.7	-0.1	0.5	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	0.9	-0.6	-0.7	-0.6	0.7	-0.3	0.2	-0.5	-1.2	-0.5	-0.6	0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.0	0.6	-0.6	-0.8	-0.9	-1.0	-0.5	-0.2	-0.7	0.1	-0.2	-0.7	-0.2
Medication: Paracetamol	0.3	0.6	2.1	1.2	0.4	0.3	0.2	1.0	0.9	1.4	0.2	0.6	0.6	0.3	0.6
Gout (self-reported)	0.3	0.4	1.8	-1.3	-0.5	-0.4	0.1	-0.3	-0.4	-0.8	-0.3	-1.0	-0.0	-0.4	-0.8
High blood pressure (siblings)	0.3	0.4	2.8	0.4	-0.3	-0.5	-0.5	-1.7	-0.2	0.1	-0.3	-0.7	-0.3	-0.4	0.3
Health satisfaction	0.3	0.4	1.5	1.2	-0.5	-0.6	-1.1	0.3	0.1	0.5	-0.3	-0.8	-0.7	-0.6	0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.0	0.3	0.7	0.7	0.8	-0.5	0.3	-0.8	1.0	0.1	-0.6	0.8	-0.2
Leg fat mass (right)	0.3	1.3	3.9	1.7	0.5	0.6	1.0	-0.9	1.2	1.8	0.2	-0.3	0.6	0.7	2.0
Had major operations	0.3	0.4	2.9	-0.6	-0.1	-0.0	-0.0	1.7	0.6	0.7	0.1	-0.5	0.3	-0.0	0.3
Age at last live birth	0.3	0.4	2.0	0.3	-0.2	-0.4	-0.5	-0.2	-0.1	0.4	-0.2	-1.4	1.2	-0.4	-0.6
Medication: Gliclazide	0.3	0.3	2.1	0.1	0.1	0.2	1.5	-0.1	0.2	0.6	-0.0	0.9	0.3	0.2	0.5
Wears glasses or contact lenses	0.3	0.4	2.2	-0.9	0.1	0.2	0.2	-1.1	-0.0	-0.1	-0.1	1.5	0.1	0.2	0.0
Medication: Bendroflumethiazide	0.3	0.4	2.9	1.7	0.1	0.1	-0.2	-0.3	0.4	0.6	0.1	0.4	-0.4	0.1	0.9
Alcohol drinker status: Never	0.3	0.4	1.4	-0.1	0.6	0.7	1.1	0.0	0.4	0.5	0.5	1.2	0.4	0.7	0.4
Number of operations (self-reported)	0.3	0.4	1.7	0.2	0.1	0.2	0.9	0.5	0.5	1.3	-0.2	-0.4	1.1	0.2	0.6
Pain experienced in last month	0.3	0.5	3.2	-1.8	-0.6	-0.4	0.4	1.0	-0.4	-0.4	-0.7	-0.2	0.2	-0.4	-0.6
Depressed Affect (Nagel 2018)	0.2	0.3	1.4	1.2	0.3	0.2	1.2	0.4	0.4	0.4	0.3	-0.1	0.3	0.3	0.5
Worry (Nagel 2018)	0.2	0.5	1.7	0.9	0.4	0.2	1.3	-0.3	-0.2	-0.0	0.8	1.2	-0.4	0.2	0.7
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	-0.2	-0.4	-0.3	-0.3	0.3	0.2	0.9	-0.2	-0.8	0.3	-0.4	0.4
Prostate Cancer	0.2	0.2	1.1	0.6	-0.3	-0.4	-0.5	0.7	0.1	0.2	-0.2	-1.0	-0.1	-0.4	-0.5
Primary Biliary Cirrhosis	0.2	0.3	2.0	-0.3	0.2	0.2	0.9	1.4	0.4	0.3	0.1	0.1	0.4	0.2	-0.1
Ulcerative Colitis	0.2	0.3	0.7	0.0	0.7	0.5	0.5	-0.6	0.7	0.3	0.9	0.1	0.5	0.5	-0.2
Lung FVC	0.2	1.1	3.1	-0.6	1.2	1.2	1.3	0.7	1.0	1.0	1.0	-0.5	1.8	1.2	0.5
Serious illness, injury or assault to yourself	0.2	0.2	1.1	0.1	0.3	0.1	0.0	1.1	-0.1	-0.8	0.4	-0.6	-0.4	0.0	-0.6
Stomach or abdominal pain in last month	0.2	0.2	1.8	0.2	0.4	0.4	0.5	-0.1	0.4	0.3	0.1	-1.3	-0.1	0.4	0.1
Waist circumference	0.2	0.7	2.2	1.5	0.5	0.6	0.5	-0.3	1.2	1.1	0.0	-0.4	0.0	0.7	1.5
Nervous feelings	0.2	0.5	2.1	-0.1	0.6	0.5	1.2	-0.1	0.2	0.1	0.7	1.4	-0.0	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.6	-0.7	0.0	-0.1	0.0	-1.3	-0.5	-0.9	-0.1	0.3	0.3	-0.1	-1.2
Illnesses of siblings	0.2	0.3	1.6	-1.3	-0.1	-0.0	0.6	0.6	-0.3	-0.5	0.1	0.3	0.2	-0.1	-0.7
Alcohol intake versus 10 years previously	0.2	0.3	1.1	0.7	-0.3	-0.3	0.1	-0.1	-0.5	-1.0	-0.5	-0.1	-1.1	-0.3	-0.7
Falls in the last year	0.2	0.3	1.4	0.5	-0.4	-0.5	-0.2	-0.2	-0.2	0.9	-0.2	1.2	0.6	-0.5	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	0.6	-0.6	-0.7	-0.6	-0.8	-0.2	-0.3	-0.0	-0.4	0.4	-0.7	-0.6	0.2
Medication: Lansoprazole	0.2	0.2	1.2	1.1	0.3	0.2	-0.3	-0.1	0.1	0.5	-0.0	0.2	0.2	0.3	0.8
Arm fat mass (right)	0.2	0.8	2.6	1.6	0.6	0.6	1.0	-0.7	1.1	1.2	0.2	-0.1	0.3	0.6	1.4
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-1.0	-0.7	-0.6	0.1	-0.5	-0.7	-0.7	-0.7	-0.6	-0.7	-0.6	-0.8
Whole body fat mass	0.2	0.8	2.2	1.4	0.3	0.3	0.8	-1.0	0.9	1.3	-0.0	-0.7	0.1	0.4	1.5
Leg pain on walking	0.2	0.3	1.4	0.6	-0.2	-0.1	-0.4	-0.0	0.1	1.2	-0.6	0.5	0.5	-0.1	0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	0.1	-0.0	-0.1	-0.4	0.8	0.0	0.5	-0.1	0.8	0.8	-0.1	0.4
Illnesses of father: Heart disease	0.2	0.2	1.1	-0.2	-0.1	-0.1	-0.3	-1.1	-0.5	-0.4	-0.3	0.9	-0.5	-0.0	-0.2
Mood swings	0.2	0.4	1.8	0.1	0.7	0.6	1.3	0.2	0.9	0.0	0.8	-0.2	0.3	0.7	0.2
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	1.1	-0.1	-0.2	0.4	-0.8	0.0	0.3	0.1	0.8	-0.5	-0.2	0.7
Medication: Paracetamol	0.2	0.3	1.4	1.2	0.2	0.1	-0.2	0.6	0.5	1.0	0.1	0.7	0.1	0.2	0.5
Illnesses of father: High blood pressure	0.2	0.3	1.9	1.4	-0.1	-0.2	0.0	-0.5	-0.3	-0.0	0.1	0.7	-0.6	-0.2	0.2
Ever depressed for a whole week	0.2	0.2	1.3	0.6	0.3	0.2	-0.5	-1.1	0.2	0.6	0.0	0.0	0.4	0.2	-0.2
Neuroticism (Nagel 2018)	0.1	0.3	1.4	1.2	0.1	-0.1	1.2	-0.5	-0.3	-0.1	0.2	-0.0	-0.2	-0.0	0.7
Crohns Disease (2017)	0.1	0.2	1.0	0.2	-0.3	-0.1	0.4	0.7	-0.2	-0.1	-0.6	1.0	-0.5	-0.2	-0.0
Crohns Disease (2012)	0.1	0.2	0.5	0.4	-0.4	-0.3	-0.3	0.2	-0.4	0.4	-0.7	-0.1	-0.7	-0.3	0.0
HbA1C	0.1	0.1	0.5	-0.4	-0.0	0.2	0.1	0.2	0.4	0.2	-0.2	0.7	0.2	0.1	0.3
LDL Cholesterol	0.1	0.2	0.6	0.2	-0.3	-0.6	-0.6	-0.8	-0.3	0.5	-0.3	0.2	0.0	-0.2	0.1
BMI	0.1	0.4	2.7	0.7	0.0	0.0	0.1	-1.6	0.4	0.7	-0.4	-0.5	0.1	0.1	1.0
Systolic Blood Pressure	0.1	0.7	3.8	1.9	-0.5	-0.7	-0.0	-0.5	0.1	0.8	-0.3	-0.8	-1.0	-0.6	1.2
Hair Pigment	0.1	1.7	4.4	0.3	1.4	1.5	0.6	1.7	1.6	0.8	1.2	2.1	0.7	1.5	1.1
Systolic blood pressure, automated reading	0.1	0.3	1.0	0.6	-0.0	-0.1	0.3	0.4	0.6	0.7	0.0	-0.8	-0.4	-0.1	1.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.7	0.0	-0.1	0.1	0.2	-0.5	0.3	-0.0	0.3	-0.6	-0.5	0.1	0.9
Trunk fat percentage	0.1	0.6	1.9	-0.0	-0.8	-0.8	-0.2	-1.4	-0.3	0.0	-1.1	-0.8	-1.1	-0.7	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.8	-0.1	0.0	-0.1	0.1	-1.3	-0.3	-0.4	0.1	0.9	0.3	-0.1	-0.6
Sitting height	0.1	1.0	7.1	2.7	0.1	-0.2	-0.4	0.2	-0.2	1.3	0.4	0.5	0.5	-0.2	1.4
Trunk fat mass	0.1	0.5	1.4	1.0	-0.2	-0.2	0.3	-1.2	0.3	0.8	-0.5	-0.8	-0.5	-0.1	1.0
Number of incorrect matches in round	0.1	0.2	1.0	0.2	-0.3	-0.3	0.2	-1.0	-0.7	-0.6	-0.0	-0.2	-0.7	-0.4	-0.1
Forced vital capacity (FVC)	0.1	0.3	1.3	1.1	0.4	0.1	0.1	0.5	-0.2	0.0	0.3	-1.1	0.7	0.2	-0.2
Mouth/teeth dental problems	0.1	0.1	0.4	-0.4	0.1	0.3	0.4	0.4	0.2	0.4	-0.1	0.3	0.6	0.3	-0.1
Hip circumference	0.1	0.6	2.2	0.3	0.5	0.6	0.8	0.0	1.2	1.1	0.2	0.3	0.6	0.7	1.5
Standing height	0.1	0.9	5.4	2.3	-0.2	-0.4	-0.5	0.8	-0.2	1.2	0.0	-0.8	0.1	-0.4	1.2
Pulse wave reflection index	0.1	0.1	0.2	0.3	0.2	0.0	-0.2	-0.3	-0.0	0.4	0.2	0.4	0.3	0.1	-0.2
Blood clot in the leg (DVT)	0.1	0.1	0.6	-0.8	-0.3	-0.2	0.1	-0.1	0.3	0.4	-0.5	0.5	0.2	-0.2	-0.0
Forced vital capacity (FVC), Best measure	0.1	0.3	1.8	1.3	0.3	0.0	0.1	0.0	-0.2	0.4	0.3	-0.8	0.6	0.1	0.2
Body fat percentage	0.1	0.5	2.8	0.1	-0.6	-0.5	0.1	-1.7	-0.1	0.1	-1.0	-0.6	-1.0	-0.5	0.2
Leg fat percentage (right)	0.1	0.4	2.3	0.3	-0.5	-0.3	0.2	-1.5	0.2	0.7	-0.8	-0.3	-0.5	-0.3	0.8
Medication: Allopurinol	0.1	0.1	1.1	-0.2	0.1	0.1	1.1	0.4	0.1	-0.4	0.4	-0.0	-0.1	0.1	-0.3
Comparative height size at age 10	0.1	0.5	2.2	1.5	-0.0	-0.2	-0.3	-0.7	-0.3	0.6	0.1	-1.4	-0.1	-0.2	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.8	-0.1	0.1	0.1	-0.1	-0.9	0.1	0.6	-0.2	0.7	0.1	0.1	0.6
Arm fat percentage (left)	0.1	0.2	1.2	0.1	-0.2	-0.2	0.5	-1.1	0.2	-0.1	-0.6	-0.6	-0.6	-0.1	-0.0
Average weekly red wine intake	0.1	0.2	1.2	0.6	-0.3	-0.3	-0.3	0.7	0.0	0.4	0.0	-1.1	0.2	-0.3	-0.2
Ever had bowel cancer screening	0.1	0.1	0.4	0.4	0.0	-0.2	-0.3	-0.4	-0.2	0.6	-0.2	0.4	-0.2	-0.2	0.3
Arm fat mass (left)	0.1	0.6	1.7	1.3	0.4	0.4	1.0	-0.8	0.9	1.0	0.1	-0.4	0.2	0.5	1.2
Leg fat percentage (left)	0.1	0.4	1.3	0.7	-0.1	0.0	0.6	-1.1	0.5	0.9	-0.4	0.1	-0.1	0.1	1.0
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.4	0.6	0.2	0.2	-0.4	0.2	0.2	0.4	0.2	0.4	0.2	0.2	0.2
Diastolic blood pressure, automated reading	0.1	0.4	3.7	-0.1	-0.2	-0.2	0.2	-0.1	-0.2	-0.7	-0.2	-1.9	-0.8	-0.2	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.8	-0.9	-0.4	-0.3	-0.1	-0.2	0.1	0.0	-0.6	0.4	-0.2	-0.3	-0.3
Blood Eosinophil Count	0.0	0.2	0.9	0.1	0.1	0.1	0.3	0.9	0.4	0.1	-0.0	-0.9	0.2	0.1	0.1
Tanning	0.0	0.2	1.3	-1.2	0.0	-0.0	-0.4	-0.0	-0.0	0.0	-0.2	0.0	0.8	-0.0	0.1
Arm fat percentage (right)	0.0	0.2	0.6	0.5	-0.1	-0.1	0.6	-0.8	0.3	0.0	-0.4	-0.2	-0.5	-0.0	0.1

Hub : Genes

CAPZA2

Models

Trait associations