Hub : Genes

CCDC125

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.5600 0.0550 0.0e+00 0.155 0.247 0.279 0.203 0.287 1.8e-18 8.6e-30 5.3e-34 3.6e-24 4.0e-35
2 GTEx Adipose Subcutaneous 0.1680 0.0550 3.5e-07 0.119 NA 0.096 NA 0.120 5.9e-10 NA 3.0e-08 NA 5.5e-10
3 GTEx Adipose Visceral Omentum 0.1220 0.0530 1.2e-03 0.024 NA 0.030 NA 0.033 2.1e-02 NA 1.0e-02 NA 7.5e-03
4 GTEx Artery Tibial 0.0899 0.0402 2.3e-03 0.020 NA 0.011 NA 0.014 9.6e-03 NA 4.6e-02 NA 2.7e-02
5 GTEx Brain Cerebellar Hemisphere 0.3450 0.1010 2.7e-04 0.238 NA 0.004 NA 0.135 8.5e-07 NA 2.5e-01 NA 2.6e-04
6 GTEx Brain Cerebellum 0.3020 0.1090 1.5e-03 0.086 NA 0.113 NA 0.083 1.6e-03 NA 3.3e-04 NA 1.9e-03
7 GTEx Breast Mammary Tissue 0.2010 0.0610 2.1e-07 0.156 NA 0.145 NA 0.143 2.2e-08 NA 6.9e-08 NA 8.5e-08
8 GTEx Breast Mammary Tissue (Male) 0.1863 0.0805 2.1e-03 0.230 NA 0.127 NA 0.016 4.7e-06 NA 7.3e-04 NA 1.3e-01
9 GTEx Breast Mammary Tissue (Female) 0.1931 0.0811 9.7e-04 0.060 NA 0.100 NA 0.070 7.1e-03 NA 6.5e-04 NA 4.1e-03
10 GTEx Cells Transformed fibroblasts 0.1320 0.0450 1.3e-07 0.111 NA 0.148 NA 0.122 1.1e-08 NA 3.1e-11 NA 2.0e-09
11 GTEx Colon Transverse 0.2450 0.0700 7.2e-09 0.260 NA 0.259 NA 0.257 1.0e-12 NA 1.2e-12 NA 1.4e-12
12 GTEx Esophagus Gastroesophageal Junction 0.1330 0.0580 7.9e-04 0.083 NA 0.049 NA 0.015 6.5e-04 NA 7.5e-03 NA 9.4e-02
13 GTEx Esophagus Mucosa 0.1190 0.0450 1.9e-04 0.017 NA 0.046 NA 0.037 2.3e-02 NA 5.1e-04 NA 1.5e-03
14 GTEx Esophagus Muscularis 0.0730 0.0370 5.0e-03 0.035 NA 0.024 NA 0.024 3.3e-03 NA 1.2e-02 NA 1.3e-02
15 GTEx Heart Left Ventricle 0.1365 0.0558 6.6e-05 0.053 NA 0.069 NA 0.060 8.8e-04 NA 1.5e-04 NA 3.8e-04
16 GTEx Lung 0.0952 0.0302 9.5e-08 0.127 NA 0.127 NA 0.152 6.4e-10 NA 6.3e-10 NA 1.1e-11
17 GTEx Muscle Skeletal 0.2591 0.0505 0.0e+00 0.194 NA 0.248 NA 0.240 9.9e-19 NA 3.3e-24 NA 2.3e-23
18 GTEx Nerve Tibial 0.2513 0.0860 6.7e-05 0.125 NA 0.099 NA 0.117 4.0e-09 NA 1.7e-07 NA 1.3e-08
19 GTEx Ovary 0.3040 0.0980 1.7e-04 0.115 NA 0.209 NA 0.087 9.5e-04 NA 7.3e-06 NA 3.8e-03
20 GTEx Pancreas 0.2590 0.0920 1.1e-06 0.248 NA 0.234 NA 0.239 7.3e-11 NA 2.9e-10 NA 1.8e-10
21 GTEx Pituitary 0.3990 0.0970 5.3e-07 0.072 NA 0.176 NA 0.078 7.1e-03 NA 3.5e-05 NA 5.3e-03
22 GTEx Prostate 0.1460 0.0660 3.1e-03 0.152 NA 0.080 NA 0.130 1.3e-04 NA 4.8e-03 NA 3.9e-04
23 GTEx Skin Not Sun Exposed Suprapubic 0.3410 0.0710 1.8e-13 0.386 NA 0.364 NA 0.375 2.1e-22 NA 6.3e-21 NA 1.2e-21
24 GTEx Skin Sun Exposed Lower leg 0.2840 0.0590 0.0e+00 0.303 NA 0.292 NA 0.293 1.9e-25 NA 1.9e-24 NA 1.6e-24
25 GTEx Spleen 0.2210 0.0740 2.2e-05 0.147 NA 0.140 NA 0.171 1.3e-04 NA 2.0e-04 NA 3.7e-05
26 GTEx Stomach 0.1550 0.0660 8.4e-05 0.092 NA 0.047 NA 0.058 3.6e-05 NA 2.6e-03 NA 9.0e-04
27 GTEx Testis 0.0840 0.0430 7.4e-03 0.004 NA 0.020 NA 0.008 2.0e-01 NA 4.4e-02 NA 1.4e-01
28 GTEx Thyroid 0.2820 0.0700 2.6e-15 0.286 NA 0.299 NA 0.293 4.0e-22 NA 3.2e-23 NA 9.6e-23
29 GTEx Whole Blood 0.1620 0.0470 1.1e-11 0.147 NA 0.169 NA 0.155 1.7e-13 NA 2.2e-15 NA 3.9e-14
30 METSIM Adipose 0.1229 0.0305 0.0e+00 0.154 0.180 0.191 0.177 0.175 2.6e-22 4.1e-26 8.1e-28 8.7e-26 1.7e-25
31 NTR Blood 0.0162 0.0069 3.1e-05 0.015 0.014 0.014 0.013 0.018 8.1e-06 1.6e-05 1.3e-05 3.0e-05 1.3e-06
32 ROSMAP Brain Pre-frontal Cortex 0.0488 0.0248 4.3e-04 0.035 0.017 0.040 0.037 0.052 2.0e-05 2.6e-03 5.7e-06 1.5e-05 2.5e-07
33 TCGA Breast Invasive Carcinoma 0.1155 0.0436 5.4e-04 0.035 -0.001 0.030 NA 0.032 1.0e-07 6.9e-01 8.0e-07 NA 2.7e-07
34 TCGA Head and Neck Squamous Cell Carcinoma 0.0293 0.0216 2.6e-03 0.013 0.021 0.017 NA 0.017 1.2e-02 1.6e-03 4.0e-03 NA 4.3e-03
35 TCGA Brain Lower Grade Glioma 0.1623 0.0625 7.3e-06 0.028 0.058 0.046 NA 0.046 3.6e-04 3.9e-07 6.1e-06 NA 5.1e-06
36 TCGA Lung Adenocarcinoma 0.2523 0.1180 4.2e-04 0.032 0.008 0.023 NA 0.056 1.2e-04 3.5e-02 9.1e-04 NA 4.0e-07
37 TCGA Lung Squamous Cell Carcinoma 0.1179 0.0547 4.7e-03 0.057 -0.002 0.052 NA 0.059 4.1e-07 5.8e-01 1.4e-06 NA 2.5e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Bipolar Disorder (2018) 0.8 1.3 6.3 -0.4 -0.4 -0.4 1.0 0.3 -0.6 -0.9 0.0 -1.6 0.8 -0.1 -0.8 -1.6 -1.0 -2.3 -0.9 -2.5 -0.5 -1.9 -0.6 -0.5 -0.9 -0.5 -0.7 -1.0 -0.9 -2.2 -0.7 -1.2 -1.9 -1.6 -1.6 0.0 1.0 -0.0 0.0 0.0
Bipolar Disorder or Schizophrenia 0.2 0.5 3.3 0.4 -0.1 0.0 1.4 0.5 0.3 -0.5 0.5 -1.7 0.7 0.5 -0.9 -1.0 0.1 -1.2 -0.3 -1.1 -0.3 -1.0 -0.4 0.1 -0.5 -0.3 -0.4 -0.2 -0.4 -1.8 -0.2 -0.2 -0.4 -0.4 -0.4 0.0 0.7 0.5 0.0 0.0
Depressed Affect (Nagel 2018) 0.4 0.9 5.3 -1.2 0.1 -1.6 -2.3 -1.1 -1.1 0.6 0.7 0.7 -0.8 0.2 0.4 -0.8 0.5 -1.7 0.5 -0.1 0.5 -0.3 0.5 0.1 0.9 0.6 0.5 0.9 0.3 0.4 0.8 0.5 1.1 1.2 -0.9 -1.2 -0.3 -1.2 -1.5 -1.4
Depression (Nagel 2018) 0.6 0.8 3.7 -0.2 -0.5 -1.8 -1.9 -1.4 -1.0 0.1 0.3 -0.0 -0.2 -0.5 -0.6 -1.3 0.0 -1.7 0.1 0.6 -0.1 -0.6 -0.2 -0.2 0.2 -0.0 -0.2 0.3 -0.3 -0.3 0.0 0.3 0.8 1.2 -1.4 -1.7 -0.1 -0.9 -1.9 -1.7
Intelligence (Savage-Jansen 2018) 1.1 3.5 7.7 0.9 -2.1 -1.0 0.5 -1.4 -0.9 -2.1 -2.5 -1.6 1.1 -2.1 -2.6 -2.3 -2.5 -0.3 -2.2 0.2 -2.1 -1.7 -2.1 -2.8 -2.4 -2.0 -2.2 -2.3 -2.0 -2.6 -2.5 -2.4 -2.3 -1.7 -2.0 -1.4 0.9 0.5 -0.0 -1.1
Neuroticism (Nagel 2018) 0.8 1.9 4.4 -1.9 1.0 -0.6 -2.0 -0.8 -1.0 1.3 1.5 0.6 -1.7 1.4 0.4 -0.3 1.3 -0.8 1.5 0.4 1.5 1.0 1.5 1.0 2.1 1.6 1.5 1.8 1.3 1.0 1.7 1.5 1.9 1.9 -0.1 -0.9 -1.1 -2.0 -1.9 -1.1
Schizophrenia (2018) 0.1 0.2 0.9 0.0 0.1 0.4 0.9 0.4 0.8 0.0 0.5 -1.0 0.2 0.7 -0.5 -0.1 0.9 0.2 0.4 0.6 0.0 0.2 -0.0 0.7 0.1 -0.0 -0.0 0.5 0.2 -0.7 0.2 0.7 1.0 0.7 0.5 0.0 0.0 0.7 0.0 0.0
Schizophrenia vs Biploar Disorder 0.2 0.3 1.4 0.0 0.2 -0.8 -0.7 -0.2 0.1 0.7 -0.1 1.2 -0.3 -0.1 -0.6 0.1 0.4 0.3 0.5 0.8 0.4 0.4 0.5 -0.3 0.7 0.4 0.5 0.5 0.6 1.1 0.4 0.4 1.2 0.5 0.6 0.0 -0.6 0.0 0.0 0.0
Worry (Nagel 2018) 0.5 1.0 4.1 -1.0 0.9 0.4 -0.0 0.4 0.9 0.6 1.3 -0.3 -0.8 0.9 -0.4 0.8 1.3 -0.1 1.1 1.0 0.8 1.5 0.7 1.5 1.4 0.9 0.7 1.2 0.5 1.2 0.9 1.5 1.4 1.5 -0.5 -1.3 -0.2 -0.1 -2.0 -1.2
Alzheimer’s Disease (in mother) 0.4 0.5 2.3 0.6 -0.9 -0.7 0.1 -0.9 -0.6 -0.7 -0.3 -0.2 0.5 -1.1 -0.6 -0.7 -0.7 0.3 -0.7 0.2 -0.8 -1.0 -0.8 -1.5 -1.0 -0.8 -0.9 -0.5 -1.0 -0.8 -0.8 -0.4 -0.6 -0.5 -0.4 -0.4 0.6 0.3 -0.3 -0.1
Alzheimer’s Disease (in father) 0.2 0.2 0.8 -0.5 0.4 0.8 -0.9 0.5 0.3 0.4 -0.3 -0.2 -0.4 0.7 -0.6 -0.5 0.7 -0.1 0.4 -0.2 0.4 0.3 0.5 0.4 0.2 0.3 0.5 0.4 0.4 0.1 0.6 0.4 0.3 0.0 -0.2 -0.4 0.1 0.1 -0.3 -0.2
Alzheimer’s Disease (including proxy) 0.2 0.3 0.8 0.6 -0.9 -0.7 -0.5 -0.7 -0.5 -0.5 -0.4 -0.4 0.3 -0.7 -0.5 -0.9 -0.2 0.0 -0.5 0.3 -0.8 -0.7 -0.7 -0.9 -0.8 -0.8 -0.7 -0.2 -0.7 -0.6 -0.6 0.0 -0.0 -0.1 -0.4 -0.6 0.6 0.3 -0.5 -0.2
Crohns Disease (2017) 0.2 0.4 1.2 -0.1 -0.5 -0.4 -0.5 -0.4 -0.6 -0.3 -0.3 -0.3 -0.3 -0.7 -0.1 -1.0 -1.0 -0.2 -0.7 -0.2 -0.5 -1.1 -0.4 -1.0 -0.5 -0.4 -0.5 -0.8 -0.2 -1.0 -0.8 -1.1 -1.0 -0.6 -0.6 -0.2 -0.5 -0.8 0.6 -0.3
Irritable Bowel Disease (IBD) 0.3 0.7 2.6 -0.2 -0.7 -0.6 -0.9 -0.6 -0.6 -0.6 -0.5 -0.7 -0.1 -0.9 -1.1 -1.4 -0.8 -0.5 -0.7 0.0 -0.6 -1.3 -0.6 -0.6 -0.7 -0.6 -0.7 -0.8 -0.4 -1.6 -0.9 -1.0 -0.8 -0.4 -1.6 -1.5 -0.2 -0.6 -0.8 -1.4
Ulcerative Colitis (UC) 0.3 0.5 2.6 -0.3 -0.1 -0.1 -0.9 0.6 0.6 -0.4 -0.0 -0.9 0.2 -0.4 -1.4 -0.6 -0.1 -0.5 -0.3 -0.1 -0.3 -0.8 -0.5 0.4 -0.4 -0.3 -0.4 -0.5 -0.3 -1.3 -0.4 -0.4 -0.1 -0.4 -1.4 -1.6 0.4 0.4 -1.2 -1.5
Major Depression (MDD) 0.2 0.2 1.5 0.8 0.0 -0.6 -0.6 -0.9 -1.0 -0.2 0.2 -0.7 0.3 0.3 0.2 -0.2 -0.1 -0.5 -0.0 -0.8 0.2 -0.9 0.1 0.2 0.3 0.3 0.1 0.2 -0.2 0.0 0.4 -0.2 0.3 0.1 -0.4 0.0 0.1 -1.2 0.0 0.0
Reaction Time 1.1 2.1 9.0 2.2 -0.6 0.4 3.0 0.9 1.5 -1.0 -0.5 -1.6 2.5 -0.8 -0.9 0.1 -0.4 0.4 -1.1 -1.0 -1.1 -1.1 -1.5 -0.4 -1.4 -1.1 -1.5 -1.4 -1.5 -1.8 -1.2 -1.1 -0.9 -1.6 0.7 1.9 2.3 2.3 2.2 1.8
Verbal and Numeric Reasoning (VNR) 0.3 0.8 2.5 -0.2 -0.9 -0.5 -0.6 -0.3 0.3 -0.9 -1.0 -0.4 0.2 -1.0 -1.2 -0.9 -1.2 -0.5 -0.9 0.9 -1.0 -0.5 -1.0 -1.6 -0.8 -1.0 -1.0 -0.9 -0.7 -0.8 -1.2 -1.0 -0.8 -0.5 -1.3 -1.4 0.2 0.5 -0.9 -1.3
Breast Cancer 0.4 1.0 8.5 0.0 -0.0 -0.0 -0.9 -0.2 0.6 0.5 -0.3 2.2 -0.3 -0.5 0.3 0.8 1.1 1.4 0.8 2.9 0.1 0.9 0.1 -1.0 0.2 0.1 0.2 0.8 0.4 0.4 0.1 1.3 1.4 1.4 -0.1 -1.2 -0.7 0.3 -2.4 -0.7
Ovarian Cancer 2.5 3.3 9.4 1.9 -2.3 -2.6 -1.1 -1.6 -1.2 -2.0 -1.7 -1.4 1.8 -2.4 -1.6 -1.9 -1.9 -0.6 -2.0 -0.2 -2.3 -3.1 -2.1 -1.9 -2.6 -2.2 -2.2 -1.9 -2.0 -2.6 -2.1 -1.9 -1.3 -1.4 -0.8 -0.2 1.4 0.7 0.5 0.1
Prostate Cancer 1.2 1.6 3.6 1.3 -1.5 -1.6 1.1 -1.9 -1.9 -1.5 -1.2 -1.8 1.0 -0.9 -0.9 -1.5 -1.6 -0.4 -1.5 -0.7 -1.3 -1.4 -1.3 -0.8 -1.4 -1.2 -1.5 -1.2 -1.5 -1.6 -1.4 -1.4 -1.3 -0.9 -1.0 0.0 0.7 -1.6 0.0 0.0
Age at First Birth 0.6 0.8 3.9 -0.2 0.7 0.9 0.6 1.0 2.0 0.7 1.0 0.5 -0.6 0.5 0.1 1.1 1.2 1.5 1.0 1.9 0.5 0.7 0.5 1.2 0.3 0.5 0.5 0.7 0.9 0.6 0.6 1.1 1.0 0.6 0.9 0.2 -0.8 1.3 -0.6 0.6
Bipolar Disorder (2011) 0.8 0.7 3.5 0.0 1.3 1.3 0.0 1.0 0.6 0.7 0.8 -0.1 -0.5 1.9 0.8 0.9 1.2 0.2 1.2 -0.3 1.2 0.8 1.1 1.2 0.9 1.1 1.0 1.0 1.0 -0.2 1.2 1.0 0.4 0.4 0.8 0.0 -0.5 -0.3 0.0 0.0
Body Mass Index (BMI) (2010) 0.5 0.7 3.1 0.0 0.8 -0.0 -1.4 -0.1 -0.0 0.9 0.7 0.7 -0.9 1.0 0.7 0.2 0.8 0.3 1.1 0.5 0.9 0.0 1.1 0.3 0.9 0.9 1.1 1.1 1.1 -0.2 1.2 0.9 1.8 1.3 1.1 0.0 -1.1 -0.2 0.0 0.0
Coronary Artery Disease (CAD) 0.6 0.7 6.2 0.0 -0.3 -0.9 -1.6 -2.2 -2.2 -0.0 0.1 0.1 -0.1 -0.2 0.7 -0.8 -0.2 0.6 0.2 0.7 0.2 0.0 0.4 -0.8 0.1 0.3 0.3 0.4 0.1 -0.7 0.3 0.1 0.5 0.4 0.7 0.0 -1.0 -2.5 0.0 0.0
Crohns Disease (2012) 0.2 0.3 1.8 0.0 0.1 0.2 -0.5 -0.4 -0.0 0.6 0.7 0.4 -1.0 0.1 -0.3 -0.4 0.2 0.8 0.4 1.4 0.2 -0.1 0.4 -0.9 0.6 0.2 0.3 0.5 0.7 0.1 0.1 0.2 0.8 0.8 0.4 0.0 -1.1 -0.2 0.0 0.0
Mean Putamen Volume 0.6 0.7 2.4 1.5 -1.3 -1.5 -0.7 -1.5 -1.3 -0.6 0.6 0.1 0.9 -0.9 1.0 -0.5 -0.7 0.5 -0.8 0.3 -0.9 -0.9 -0.7 -1.0 -0.8 -1.0 -0.7 -0.6 -0.6 -1.0 -0.6 -0.7 0.2 -0.4 1.3 0.0 -0.2 -0.4 0.0 0.0
Fasting Glucose 0.5 0.6 5.8 0.1 -0.8 -1.6 -0.9 -0.7 -1.1 -0.5 -0.7 0.1 0.5 -0.9 -0.1 -1.1 -0.8 -1.3 -0.7 -1.0 -0.6 -2.4 -0.6 -0.7 -0.5 -0.6 -0.6 -0.6 -0.8 -0.0 -0.5 -0.7 -0.0 -0.3 -0.3 0.0 0.7 -0.3 -0.2 -0.0
HbA1C 1.1 1.2 5.5 0.0 0.8 1.5 1.4 0.2 0.7 0.9 1.4 0.6 -1.3 0.9 1.4 0.8 1.0 2.3 1.3 1.6 0.9 1.5 0.9 1.3 1.1 0.9 0.9 1.5 1.1 0.5 0.8 1.1 1.2 2.0 0.6 0.0 -0.6 0.8 0.0 0.0
HDL Cholesterol 0.6 0.9 2.5 0.0 -0.9 0.4 0.8 -0.1 0.3 -1.3 -1.6 -1.5 1.0 -1.2 -1.5 -0.3 -1.3 0.1 -1.3 -0.9 -1.1 0.1 -1.2 -0.1 -1.0 -1.0 -1.2 -1.4 -1.3 -0.1 -1.2 -1.2 -1.2 -1.1 -0.8 0.0 1.3 0.4 0.0 0.0
LDL Cholesterol 0.3 0.5 1.5 0.0 -0.8 -1.2 -0.1 -1.0 -1.1 -0.5 0.2 -0.4 0.6 -0.6 -0.7 -1.1 -0.8 -1.0 -0.8 -0.4 -0.6 -1.0 -0.6 -0.8 -0.7 -0.6 -0.6 -0.8 -0.5 -1.0 -0.7 -0.9 -0.7 -0.7 -0.1 0.0 0.1 -0.6 0.0 0.0
Lupus 0.2 0.4 2.2 -0.5 0.8 0.9 -1.0 0.3 0.2 0.1 -0.3 -1.0 -0.3 0.8 -0.4 0.1 -0.2 -0.2 0.2 -1.2 0.6 1.2 0.5 1.1 -0.1 0.7 0.5 0.0 0.3 -0.5 0.6 -0.2 0.1 -0.1 -1.5 0.0 -0.1 -0.4 0.0 0.0
Neuroticism (2016) 0.7 0.9 3.5 -0.1 0.9 0.1 -1.2 0.7 1.1 1.1 0.9 1.1 -0.8 0.6 0.5 1.3 0.9 1.3 1.1 1.0 0.7 0.1 0.7 1.8 0.9 0.8 0.9 1.1 0.9 0.9 1.1 1.2 1.9 1.1 1.4 0.0 -0.5 1.4 0.0 0.0
Primary Biliary Cirrhosis 0.6 0.8 2.8 -1.4 0.9 1.3 1.7 -0.0 -1.0 0.6 0.7 0.0 -1.1 1.4 0.4 0.2 1.0 1.0 1.0 -0.9 1.1 0.3 1.1 0.7 1.1 1.1 0.9 1.0 0.9 -0.4 1.0 0.9 -0.1 0.6 -0.7 0.0 -0.7 -1.6 0.0 0.0
Rheumatoid Arthritis 0.3 0.4 2.8 0.0 0.5 0.5 0.8 1.7 0.6 0.4 0.7 0.2 0.2 -0.0 0.8 0.9 0.8 -1.4 0.2 -1.4 0.2 -0.3 -0.0 0.1 0.2 0.1 0.2 0.3 -0.1 0.6 0.0 0.7 0.1 0.0 0.2 0.0 0.7 0.9 0.0 0.0
Schizophrenia (2014) 0.1 0.2 0.8 0.0 0.4 0.1 0.1 0.4 0.3 0.4 0.9 -0.6 -0.2 0.8 -0.2 -0.4 0.9 -0.5 0.5 0.0 0.3 -0.2 0.3 0.3 0.3 0.3 0.3 0.5 0.4 -0.6 0.4 0.5 0.8 0.6 0.4 0.0 -0.3 0.1 0.0 0.0
Triglycerides 0.3 0.5 2.5 0.0 0.7 -1.1 -0.8 0.2 -0.2 0.7 1.1 0.3 -0.6 1.1 0.9 -0.1 0.6 -0.7 0.6 -0.3 0.8 -0.5 0.7 0.8 0.8 0.8 0.8 0.7 0.8 0.1 0.9 0.4 1.0 0.7 1.6 0.0 -0.9 -0.5 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.6 0.0 1.2 1.6 1.4 1.6 0.6 0.9 0.8 0.5 -0.7 1.0 1.3 1.3 1.3 0.8 1.0 -0.6 1.0 0.3 0.9 0.8 1.2 1.0 1.0 1.0 0.9 0.1 1.0 1.3 0.6 0.9 0.6 0.0 -0.3 0.1 0.0 0.0
Ulcerative Colitis 0.4 0.6 2.7 0.5 -0.8 -0.4 -0.3 -0.2 0.2 -0.7 -0.1 -1.1 0.4 -0.9 -1.6 -1.0 -0.8 0.3 -0.9 0.2 -0.8 -1.6 -0.8 -0.6 -0.8 -0.8 -0.8 -0.9 -0.8 -1.6 -0.8 -0.9 -0.4 -0.8 -0.5 0.0 0.6 1.1 0.0 0.0
Blood Eosinophil Count 0.1 0.6 3.4 -1.8 0.5 -0.0 -1.1 0.6 -0.1 0.2 0.2 1.0 -0.7 0.5 0.8 0.4 0.0 -1.8 0.1 -0.8 0.4 -0.3 0.4 -0.1 0.0 0.3 0.5 0.1 0.4 1.3 0.2 -0.1 -1.2 -0.4 -0.9 -0.9 -0.7 -1.0 -0.6 -1.4
Blood Platelet Count 0.1 0.6 2.6 0.2 0.7 1.3 1.2 1.6 0.5 0.1 0.6 -0.4 0.0 0.8 1.3 1.3 0.6 0.2 0.3 -1.1 0.3 1.0 0.1 1.2 0.3 0.3 0.3 0.4 0.0 1.5 0.1 0.8 0.3 0.4 0.9 1.1 0.5 0.3 1.1 1.0
Blood Red Count 0.2 2.0 10.5 -0.2 -0.4 -1.5 -2.0 -2.2 -3.2 -0.3 -0.3 -1.9 -0.3 0.3 0.3 -2.0 -1.5 -2.2 -0.7 -2.5 0.3 -1.7 0.4 -0.1 -0.2 0.3 0.2 -0.4 -0.2 -0.6 0.2 -1.6 -0.5 -0.7 0.8 2.1 -0.4 -2.7 3.1 1.4
Blood White Count 10.3 76.5 123.2 9.7 -10.3 -9.0 1.5 -4.3 -3.2 -10.5 -7.3 -9.2 10.7 -10.6 -6.3 -6.4 -10.2 -5.8 -11.0 -5.3 -10.7 -9.5 -10.8 -7.8 -11.1 -10.7 -10.8 -10.9 -10.8 -9.0 -10.9 -10.3 -8.4 -9.5 -2.4 3.9 9.3 4.4 9.7 3.8
Heel T-Score 0.3 2.3 9.1 0.9 1.2 1.0 -0.1 2.1 2.5 1.7 2.1 2.3 -0.2 0.1 3.0 2.7 1.6 1.3 1.2 1.1 0.7 1.1 0.5 1.0 0.4 0.6 0.7 1.1 1.0 1.0 0.7 1.6 1.9 1.4 2.4 2.0 -0.4 1.9 0.8 2.1
BMI 0.3 2.0 14.7 -1.3 0.1 0.3 0.1 0.9 -0.5 -0.8 -0.7 -1.9 0.8 0.2 -0.9 -1.8 -1.1 -3.5 -1.1 -3.8 -0.1 -1.8 -0.3 -0.2 -0.7 -0.1 -0.4 -1.3 -0.9 -1.2 -0.4 -1.7 -2.5 -2.3 -1.6 -0.7 1.4 -0.9 0.8 -1.4
Height 0.2 4.3 18.0 0.9 -2.6 -4.2 -3.1 -3.9 -3.0 -2.1 -1.6 -1.2 0.8 -2.1 -1.4 -3.1 -2.4 -2.3 -1.9 1.1 -1.9 -2.3 -1.7 -2.5 -1.9 -1.8 -1.9 -1.6 -1.7 -2.7 -1.7 -2.1 -0.9 -0.5 -1.8 -1.3 -0.1 -1.8 -0.6 -1.4
Waist Hip Ratio (WHR) 1.1 4.8 10.6 -2.0 2.4 3.3 1.8 2.4 2.8 2.0 2.3 1.1 -2.2 2.4 0.8 2.4 2.7 1.7 2.5 2.0 2.1 3.2 2.0 2.2 2.2 2.0 2.1 2.4 2.4 1.4 2.1 2.8 2.1 2.7 0.4 -1.4 -2.1 -0.1 -3.0 -1.4
Systolic Blood Pressure 0.6 3.2 9.5 0.2 -1.4 0.9 3.1 0.5 0.4 -2.0 0.1 -2.7 1.2 -1.3 -2.6 -1.1 -1.4 0.9 -1.9 -1.1 -1.8 0.5 -2.0 -1.3 -1.9 -1.8 -2.1 -2.1 -1.8 -2.9 -2.1 -1.8 -2.9 -2.2 -2.7 -2.0 1.8 -0.2 -0.2 -2.0
Smoking Status 0.2 0.5 2.3 0.5 -0.1 -1.0 -1.5 0.6 0.9 -0.2 -0.2 1.0 0.8 -1.1 1.2 1.1 -0.2 -0.6 -0.5 -0.8 -0.3 0.1 -0.4 1.0 -0.2 -0.3 -0.2 -0.6 -0.6 1.1 -0.1 -0.4 0.0 -0.7 0.0 0.6 1.0 1.1 1.1 0.5
Allergy or Eczema 0.1 0.3 1.7 -0.2 0.3 0.2 -0.9 0.7 0.4 -0.2 -0.2 -0.2 0.3 -0.2 -0.3 0.4 0.8 -0.5 0.4 -0.1 0.1 0.5 -0.2 0.2 -0.2 0.1 -0.1 0.3 -0.4 -0.5 0.0 1.0 0.4 -0.0 -0.9 -1.3 0.9 0.8 -1.3 -1.0
Cardiovascular Disease 0.6 1.8 7.2 -2.5 1.1 1.7 2.2 -0.2 -0.6 0.5 1.1 -0.4 -1.6 1.7 -1.0 -0.7 0.0 1.0 0.7 -0.1 1.2 1.0 1.1 -0.1 0.9 1.3 0.8 0.6 0.9 -1.2 1.0 0.1 -0.8 0.5 -1.8 -2.6 -1.2 -2.7 -2.4 -2.7
Hypothyroidism (self reported) 1.6 3.7 10.5 -3.0 2.5 2.8 0.4 1.7 0.8 2.1 0.4 1.7 -2.5 2.5 1.2 1.4 2.0 0.5 2.1 -0.4 2.5 1.5 2.4 1.1 3.2 2.4 2.4 2.0 2.2 3.1 2.4 1.7 0.8 1.5 -0.5 -1.4 -1.3 -0.9 -1.8 -1.4
Respiratory disease 0.3 0.6 3.3 0.9 -0.7 -0.9 -0.8 -0.4 -0.1 -0.5 -0.3 -1.0 0.5 -0.6 -1.2 -0.8 -1.1 -0.8 -0.9 -0.1 -0.6 0.1 -0.5 -0.5 -0.5 -0.6 -0.4 -0.8 -0.4 0.3 -0.5 -1.1 0.1 -0.4 0.6 1.4 -0.0 0.3 1.8 1.4
Type 2 Diabetes (T2D) (2018) 0.5 0.9 3.5 -1.3 1.5 1.9 1.8 1.5 0.5 1.1 0.5 0.6 -0.9 1.0 0.3 0.5 0.9 0.6 1.0 -1.0 1.3 1.0 1.0 -0.2 1.0 1.3 1.0 1.0 0.7 0.2 0.9 0.9 0.3 0.6 -0.3 -0.6 -0.0 -0.4 -0.7 -0.5
Lung FEV1/FVC ratio 0.1 0.6 2.0 0.0 0.9 1.0 -0.5 0.2 -0.2 0.9 0.4 0.3 -0.7 0.8 0.2 0.1 1.1 1.3 1.0 0.4 0.9 -0.1 0.7 0.6 0.9 1.0 0.7 1.0 0.6 0.0 1.0 1.1 1.4 1.3 1.0 0.5 -0.4 0.2 -0.3 0.7
Lung FVC 0.2 0.9 7.8 -0.9 -0.1 -0.7 -2.1 -1.4 -0.9 0.9 0.8 2.8 -0.6 -0.6 1.6 -0.2 -0.5 0.1 0.1 0.5 0.3 0.3 0.5 -1.3 0.3 0.4 0.4 0.1 0.6 1.1 0.2 -0.4 -0.4 0.0 -0.5 -0.5 -1.4 -2.0 -0.5 -0.7
Neuroticism 0.8 2.0 7.7 -0.8 0.8 -0.6 -1.9 -1.1 -0.6 1.3 1.5 1.1 -1.6 1.0 1.1 0.7 1.4 0.6 1.6 1.7 1.2 1.3 1.3 1.1 1.9 1.3 1.3 2.2 1.2 1.3 1.7 1.9 2.5 2.8 0.9 -0.0 -1.2 -1.3 -1.3 0.0
Chronotype (morning person) 1.5 3.4 9.6 -3.1 2.4 1.4 -1.2 0.4 -0.5 2.4 1.2 2.7 -2.7 2.2 1.8 0.7 1.6 -0.5 2.0 -0.1 2.6 1.0 2.5 0.6 2.4 2.7 2.4 1.9 2.3 2.3 2.2 1.0 0.7 1.4 -0.3 -1.1 -2.1 -2.0 -1.7 -1.4
Hair Pigment 0.0 0.8 4.4 -1.2 0.9 -0.2 -0.9 -0.2 -0.6 1.0 1.4 1.6 -0.5 0.7 1.8 0.8 0.5 -0.6 0.7 -0.7 1.1 -0.6 0.9 0.7 1.0 1.1 0.9 0.6 0.5 2.1 1.1 0.2 -0.1 -0.5 0.7 0.8 -0.5 -0.8 0.7 0.2
Tanning 0.1 1.4 3.5 1.7 -1.1 -0.2 1.4 -0.5 0.4 -1.1 0.0 -0.5 1.3 -1.2 0.6 -0.2 -1.1 0.7 -1.2 0.5 -1.3 -1.4 -1.3 -1.6 -1.3 -1.3 -1.4 -1.2 -1.0 -1.8 -1.4 -1.2 -1.0 -0.9 1.2 1.8 0.7 1.5 1.9 1.8
Hand grip strength (left) 0.3 0.8 3.2 0.6 -0.4 -1.0 -1.2 -1.6 -1.8 0.3 -0.4 1.7 -0.3 -0.3 1.4 0.4 -0.3 0.4 0.1 0.9 0.0 -0.5 0.3 -0.6 0.4 0.0 0.3 0.3 0.4 1.5 0.0 0.1 0.7 0.6 1.4 1.6 -0.8 -1.0 1.3 1.6
Number of treatments/medications taken 0.1 0.1 1.0 0.3 0.3 0.5 0.8 0.2 -0.3 0.1 0.1 -1.0 0.1 0.4 -1.0 -0.5 0.3 -0.3 0.1 -0.6 0.3 -0.7 0.1 -0.4 0.4 0.3 0.0 0.1 -0.1 0.0 0.2 0.2 -0.0 0.1 -0.1 -0.1 -0.0 -0.5 -0.0 0.0
Average weekly spirits intake 0.2 0.3 2.1 1.0 -0.6 -0.9 0.2 -0.2 0.2 -0.7 -0.2 -1.5 0.6 -0.2 -0.0 -0.3 -0.4 -0.5 -0.4 0.3 -0.5 -0.8 -0.4 -0.0 -0.7 -0.5 -0.3 -0.3 -0.4 -1.0 -0.3 -0.2 -0.1 -0.3 0.4 0.3 0.1 0.2 0.3 0.5
Sensitivity / hurt feelings 1.2 2.0 4.8 -0.6 1.1 0.3 -0.1 -0.7 -1.2 1.5 1.8 1.1 -1.3 1.5 1.6 0.5 1.5 0.9 1.6 0.5 1.6 0.3 1.7 -0.0 2.0 1.6 1.8 1.9 1.5 0.8 1.8 1.7 2.0 1.9 2.2 1.8 -1.3 -1.3 0.7 1.7
Frequency of depressed mood in last 2 weeks 0.9 1.2 3.9 -1.4 0.7 -0.6 -1.6 -0.8 -0.9 1.0 0.6 0.8 -1.4 0.9 0.4 -0.7 0.7 -1.3 1.1 0.4 1.1 0.3 1.0 0.2 1.3 1.1 0.9 1.4 0.9 0.3 1.2 1.0 1.2 1.7 -0.7 -1.4 -1.1 -1.7 -2.0 -1.6
Hearing difficulty/problems: Yes 1.4 2.2 4.8 1.5 -2.0 -1.8 1.6 -0.9 -0.8 -1.9 -2.2 -1.3 2.0 -1.5 -1.8 -1.0 -1.6 -0.9 -1.7 -0.6 -2.0 -0.7 -1.9 -1.3 -1.6 -2.0 -1.9 -1.6 -1.8 -0.9 -2.0 -1.1 -1.2 -1.1 -1.3 -0.7 1.6 0.5 -0.1 -0.7
Relative age of first facial hair 0.5 1.1 3.4 -0.2 -1.3 -1.3 -1.0 -0.8 -0.2 -0.7 -0.1 1.0 0.5 -1.9 0.2 -0.2 -1.5 -0.6 -1.2 0.5 -1.3 -0.5 -1.2 -1.3 -1.0 -1.2 -1.2 -1.3 -0.9 0.7 -1.3 -1.4 -1.7 -1.1 -1.2 -1.1 0.1 -0.4 -0.6 -1.3
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 3.8 -1.9 1.4 1.2 0.1 1.2 0.7 0.8 1.6 -0.1 -1.0 1.3 0.0 0.2 0.7 -0.6 0.8 -0.7 1.2 0.4 0.9 0.8 0.7 1.2 0.9 0.5 0.8 -0.2 0.9 0.6 -0.0 -0.1 -0.6 -0.9 -0.5 -0.2 -1.0 -1.1
Ever used hormone-replacement therapy (HRT) 0.6 0.7 2.9 -1.1 1.1 1.4 0.1 1.1 0.5 0.7 1.0 -0.3 -0.7 1.1 0.2 0.3 1.7 -0.2 0.9 -0.3 1.0 0.9 0.7 1.0 0.8 0.9 0.7 0.8 0.3 0.9 0.9 1.1 0.2 -0.0 -0.3 -1.1 -0.1 -0.2 -1.5 -1.3
Ever had hysterectomy (womb removed) 0.2 0.2 1.4 -1.2 0.3 0.2 0.3 0.3 0.9 0.4 0.8 0.3 -0.1 0.4 -0.3 -0.3 -0.1 -0.7 0.2 0.4 0.3 0.1 0.3 -0.6 0.2 0.3 0.2 0.0 0.3 -0.4 0.2 -0.1 -0.4 -0.5 -0.2 -0.7 -0.4 0.5 -0.9 -1.0
Systolic blood pressure, automated reading 0.8 2.4 7.3 0.3 -1.3 0.4 1.2 0.2 0.6 -1.6 -0.3 -2.2 1.6 -1.6 -2.4 -1.2 -1.3 -0.2 -1.7 -0.7 -1.6 0.1 -1.7 -1.6 -1.9 -1.6 -1.8 -1.9 -1.8 -2.7 -1.8 -1.6 -2.1 -2.0 -2.5 -1.9 1.8 0.3 -0.5 -1.9
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 3.9 1.7 -1.2 -1.5 0.3 -1.0 -1.2 -1.4 -1.1 -1.8 1.5 -0.9 -1.1 -0.9 -1.2 -1.1 -1.3 -0.9 -1.1 -2.0 -1.1 -0.9 -1.0 -1.1 -1.1 -1.1 -1.4 -1.1 -1.1 -1.2 -0.6 -1.0 0.5 1.4 1.2 0.2 2.0 1.3
Angina 1.5 1.9 4.6 -1.5 1.9 1.9 1.2 1.1 0.5 1.5 0.3 1.1 -1.8 2.1 0.9 0.9 1.3 1.2 1.4 0.5 1.9 0.8 1.8 1.3 1.8 1.8 1.7 1.3 1.8 1.3 1.5 1.0 0.9 1.4 1.7 1.3 -1.9 -0.3 0.6 1.1
Medication for hormone replacement therapy 0.1 0.1 0.9 0.2 0.1 0.2 0.7 0.1 -0.6 -0.3 -0.1 -0.8 0.1 0.2 -0.0 -0.2 0.5 -0.8 0.1 -0.9 0.0 -0.8 -0.2 -0.1 0.0 0.0 -0.2 0.2 -0.4 -0.2 -0.2 0.3 -0.2 -0.1 -0.3 -0.2 0.5 -0.7 0.0 -0.2
Vitamin and mineral supplements 0.3 0.4 1.6 -0.5 -0.1 0.8 1.3 0.6 0.9 -0.4 -0.2 -0.1 -0.2 -0.3 -0.2 0.5 -0.3 0.6 -0.4 0.8 -0.4 1.2 -0.3 -0.5 -0.3 -0.4 -0.3 -0.5 -0.2 0.3 -0.5 -0.3 -0.9 -0.3 -1.1 -1.2 0.1 0.5 -0.8 -1.0
Supplements: Zinc 0.8 0.9 3.4 0.5 -1.0 -1.8 -1.8 -1.1 -1.2 -0.9 -0.9 -1.2 0.1 -0.9 -0.7 -1.1 -1.5 -0.9 -0.9 -0.8 -0.9 -1.5 -1.0 -0.4 -0.8 -0.8 -1.0 -0.7 -1.0 -0.9 -0.8 -1.0 -0.5 -0.2 -0.6 -0.0 0.3 -0.4 0.8 -0.1
Medication: Co-codamol 3.6 4.2 8.8 -2.3 2.1 1.2 -1.3 0.4 1.0 2.3 1.8 1.8 -3.0 2.3 1.1 1.1 1.9 1.7 2.5 2.5 2.4 1.8 2.5 1.5 2.6 2.4 2.6 2.6 2.8 1.2 2.5 2.2 2.5 2.8 0.8 -0.7 -3.0 -0.9 -2.3 -0.6
Medication: Metformin 0.3 0.4 1.1 -0.4 0.0 0.7 1.0 -0.2 -1.0 -0.3 -1.0 -0.8 -0.0 0.5 -0.9 -1.0 -0.4 0.0 -0.3 -1.0 0.1 -0.3 -0.0 -0.4 -0.3 0.1 -0.2 -0.3 -0.2 -0.9 -0.3 -0.6 -0.8 -0.3 -1.1 -0.9 0.1 -0.9 -0.4 -1.0
Diabetes (father) 1.0 1.3 6.1 0.6 0.9 1.5 1.4 2.2 1.9 0.7 1.2 0.1 -0.1 0.7 1.2 1.7 1.4 0.6 0.8 0.0 0.4 -0.8 0.1 1.3 0.8 0.3 0.3 1.0 0.2 0.9 0.3 1.6 1.7 1.2 1.4 0.9 0.6 2.5 0.1 1.0
Diabetes (mother) 1.0 1.3 4.7 0.6 1.2 1.4 1.2 1.9 2.2 0.8 1.6 -0.3 0.0 1.0 0.5 1.9 1.6 0.1 1.1 0.5 0.8 1.5 0.7 0.8 0.4 0.7 0.8 1.0 0.8 0.3 0.8 1.5 1.5 0.7 1.7 1.3 0.1 1.7 0.3 1.3
Severe depression (siblings) 0.5 0.5 2.0 -0.9 0.6 0.4 -0.6 -0.4 -0.6 0.7 0.5 0.7 -1.1 0.8 1.4 0.4 0.6 0.8 0.8 0.2 0.8 -0.2 1.0 0.4 1.1 0.9 1.0 0.9 0.8 0.8 0.8 0.8 0.3 0.7 0.4 0.0 -1.0 -0.6 -0.2 0.1
Pack years adult smoking proportion 0.1 0.2 1.3 0.1 0.5 -0.6 -0.4 0.7 -0.0 0.5 -0.2 0.6 0.2 0.2 0.5 0.3 0.5 -0.8 0.4 -0.9 0.4 -1.1 0.4 0.1 0.3 0.3 0.4 0.4 0.3 0.4 0.3 0.5 0.4 0.2 0.3 0.2 0.1 -0.2 -0.2 0.1
Impedance of leg (right) 0.1 0.4 2.3 0.0 0.1 0.8 1.5 -0.2 0.3 0.3 0.8 -0.7 -0.7 0.3 0.0 0.1 0.2 1.5 0.4 1.1 0.2 1.0 0.2 0.5 0.4 0.1 0.2 0.5 0.4 0.2 0.1 0.4 0.4 0.9 -0.1 -0.5 -0.6 -0.1 -0.7 -0.3
Leg fat-free mass (left) 0.1 0.7 6.4 -0.3 -0.2 -1.2 -2.2 -0.4 -0.8 -0.6 -0.8 -0.3 0.5 -0.2 -0.3 -1.1 -0.6 -2.5 -0.5 -1.1 -0.1 -1.4 -0.2 -0.6 -0.5 -0.1 -0.3 -0.6 -0.5 -1.4 -0.1 -0.7 -0.3 -0.8 -0.3 0.1 0.5 -0.6 0.5 -0.1
Trunk fat percentage 0.5 1.9 10.4 -1.0 0.1 1.3 0.6 1.7 1.0 -1.4 -0.4 -3.2 0.7 0.4 -1.6 -1.2 -0.5 -3.2 -1.0 -2.4 -0.4 -0.8 -0.8 0.4 -0.6 -0.5 -0.8 -1.2 -1.1 -1.1 -0.7 -0.9 -1.8 -1.6 -2.2 -1.6 1.6 0.8 -0.2 -1.9
Hand grip strength (right) 0.5 1.4 4.6 0.5 0.1 -0.6 -1.9 -1.6 -1.8 1.0 -0.2 2.1 -0.6 0.2 1.6 0.4 0.2 0.8 0.7 1.1 0.7 0.4 1.0 -0.6 0.9 0.7 1.0 1.0 1.1 1.4 0.8 0.7 1.7 1.4 1.9 1.8 -1.5 -1.5 0.9 1.8
Townsend deprivation index at recruitment 0.3 0.4 3.4 0.3 -0.5 -1.0 -1.0 -0.0 -0.5 -0.5 -0.9 0.2 0.7 -0.5 -0.3 -0.5 -0.4 -1.1 -0.8 -0.7 -0.6 -1.8 -0.5 -0.4 -0.4 -0.6 -0.5 -0.9 -0.5 -0.2 -0.5 -0.8 -0.5 -0.8 -0.0 0.2 0.5 0.4 0.3 0.1
Current tobacco smoking 1.7 2.7 7.2 1.1 -1.2 -1.7 -1.7 0.5 0.4 -1.8 -1.4 -1.3 2.3 -2.0 -0.9 -0.5 -1.4 -2.5 -2.0 -2.2 -1.7 -1.9 -1.7 -0.8 -2.0 -1.7 -1.5 -2.1 -2.0 -0.9 -1.6 -1.9 -1.8 -2.7 -1.3 -0.1 2.5 1.7 1.3 -0.3
Average weekly fortified wine intake 0.8 0.9 2.8 0.3 -1.0 -0.8 -0.6 -0.8 -0.7 -1.0 -1.4 -0.9 0.3 -0.8 -0.8 -1.2 -1.1 -1.7 -1.0 -0.6 -0.9 -1.6 -0.9 -0.8 -0.9 -0.9 -1.0 -1.0 -1.0 0.1 -1.1 -1.0 -1.1 -0.5 -1.5 -1.1 0.5 -0.8 0.0 -0.9
Maternal smoking around birth 0.1 0.2 1.5 0.3 -0.2 -0.5 -0.8 0.0 -0.1 -0.1 0.2 -0.3 0.3 -0.2 -0.0 -0.4 -0.1 -1.0 -0.3 -0.3 -0.2 -1.2 -0.2 -0.6 -0.3 -0.3 -0.2 -0.4 -0.0 -0.7 -0.2 -0.4 -0.2 -0.4 0.0 0.4 0.1 -0.2 0.6 0.2
Fed-up feelings 0.5 0.8 5.3 -0.6 -0.4 -2.0 -2.3 -1.0 -1.1 0.0 0.1 0.7 -0.3 -0.8 0.2 -1.1 -0.4 -2.0 -0.3 -0.6 -0.2 -1.2 -0.3 -1.0 0.1 -0.1 -0.3 -0.1 -0.4 -0.1 -0.0 -0.3 -0.0 0.3 -1.3 -1.4 0.1 -1.0 -1.2 -1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 3.6 -1.0 0.2 -1.4 -1.9 -0.9 -0.7 0.7 0.8 0.9 -0.5 -0.2 0.0 -1.1 -0.1 -1.2 0.1 -0.2 0.5 -1.1 0.5 -0.7 0.4 0.5 0.4 0.1 0.3 -0.2 0.5 -0.3 0.2 -0.0 -0.8 -0.9 -0.4 -0.9 -0.7 -0.9
Relative age voice broke 2.1 3.2 7.8 1.6 -2.5 -2.3 -0.5 -1.2 -0.3 -2.0 -1.2 -1.2 1.6 -2.8 -1.0 -1.4 -2.4 -1.1 -2.4 0.1 -2.5 -1.2 -2.4 -1.9 -2.4 -2.5 -2.4 -2.3 -2.1 -1.4 -2.5 -2.3 -1.7 -1.6 -1.0 -0.2 1.2 0.9 0.9 -0.0
Taking other prescription medications 0.2 0.3 2.4 -0.3 0.4 0.9 0.8 0.0 -0.1 0.0 -0.0 -1.6 -0.2 0.7 -1.1 -0.8 0.1 -0.5 0.2 -0.5 0.4 -0.4 0.3 0.1 0.7 0.4 0.3 0.2 0.0 0.3 0.5 0.2 0.1 0.1 -0.4 -0.4 0.2 -0.3 -0.1 -0.2
Age when periods started (menarche) 0.3 0.7 2.2 0.4 -1.3 -1.2 0.5 -1.4 -1.2 -0.8 -0.2 0.1 0.5 -1.4 0.1 -0.3 -0.4 0.7 -0.7 0.8 -1.0 -0.4 -0.9 -1.5 -0.6 -1.0 -0.9 -0.5 -0.7 -1.5 -1.0 -0.2 -0.5 0.1 -1.2 -1.1 0.4 -0.8 -0.8 -0.9
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 6.8 -2.6 1.0 0.5 -1.6 -0.0 -0.2 1.3 1.3 1.5 -1.4 1.1 0.5 -0.5 -0.1 -0.5 0.7 -0.0 1.3 0.1 1.4 0.6 1.2 1.3 1.3 0.6 1.2 0.6 1.2 -0.1 0.1 0.2 -0.6 -1.3 -1.3 -1.2 -1.4 -1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 4.9 -1.2 1.7 1.9 0.1 2.2 1.6 1.3 2.1 1.5 -0.7 0.9 1.3 1.6 1.2 -0.3 0.9 -0.8 1.2 0.4 0.8 0.5 0.8 1.1 0.9 0.5 0.8 0.9 0.9 0.6 0.0 -0.4 0.3 0.0 -0.3 0.6 -0.2 -0.2
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 2.9 -1.3 1.3 1.1 -0.3 1.2 1.0 1.2 0.9 0.6 -1.4 1.5 -0.1 0.5 1.2 0.2 1.1 0.4 1.2 0.8 1.1 1.7 1.4 1.1 1.2 1.0 1.3 1.5 1.1 1.0 1.3 1.4 0.5 -0.0 -1.2 0.1 -0.4 -0.1
Qualifications: CSEs or equivalent 0.5 0.7 4.3 0.5 0.1 -0.8 -0.2 1.5 1.1 -0.5 0.0 -1.0 0.8 0.1 0.1 0.6 0.6 -1.7 -0.1 -1.4 -0.2 -1.4 -0.4 2.1 0.1 -0.3 -0.2 0.1 -0.7 0.2 0.1 0.5 0.5 -0.3 0.2 0.3 1.7 1.3 0.4 0.4
Serious illness, injury or assault to yourself 0.5 0.6 3.6 -0.9 1.2 0.7 -0.1 0.5 0.3 0.5 0.3 -0.1 -0.5 1.4 0.3 0.5 0.6 -0.9 0.7 -0.6 1.2 0.2 1.1 1.9 0.7 1.2 1.1 0.5 1.0 0.3 1.2 0.3 0.4 0.3 0.3 0.4 -0.6 -0.6 0.2 0.2
High blood pressure 0.8 2.2 9.1 -2.8 1.1 2.4 2.0 0.5 -0.3 0.4 1.1 -1.1 -1.6 1.6 -2.1 -1.4 0.1 0.9 0.5 -0.5 1.1 1.1 1.0 -0.5 0.8 1.2 0.8 0.3 0.8 -1.8 0.6 -0.2 -1.0 0.0 -2.2 -2.8 -1.1 -2.4 -2.5 -3.0
Hayfever, allergic rhinitis or eczema 0.2 0.5 2.8 -0.2 0.3 0.6 -0.7 1.2 1.0 -0.3 0.0 -0.5 0.5 -0.2 -1.0 0.3 0.4 -0.4 0.3 -0.2 -0.0 0.5 -0.3 0.2 -0.4 -0.1 -0.2 0.1 -0.4 -0.9 -0.1 0.8 0.2 -0.4 -1.1 -1.5 0.9 1.1 -1.7 -1.3
Multivitamins +/- minerals 0.5 0.6 3.1 0.6 -0.6 -1.6 -1.4 -1.1 -1.4 -0.5 -0.7 -0.7 0.8 -0.3 -0.6 -1.1 -0.6 -1.4 -0.4 -1.3 -0.3 -1.8 -0.4 0.3 -0.4 -0.3 -0.4 -0.4 -0.6 -0.8 -0.3 -0.5 0.1 -0.5 -0.0 0.5 0.5 -0.4 0.8 0.3
Stomach or abdominal pain in last month 0.9 1.1 2.5 -0.5 1.1 0.9 -0.5 0.1 0.5 0.8 0.9 0.5 -1.0 1.1 0.8 1.3 1.0 1.1 1.3 1.5 1.2 0.8 1.2 1.2 1.4 1.2 1.2 1.4 1.0 0.9 1.2 1.3 1.5 1.1 1.5 1.3 -0.7 -0.2 0.7 1.6
Supplements: Glucosamine 0.7 0.9 2.8 -1.2 1.2 0.5 -1.6 0.7 0.8 1.2 1.7 1.1 -0.7 0.9 0.6 0.8 1.2 -0.3 1.2 0.1 1.1 1.1 1.0 0.4 0.9 1.1 1.1 1.3 0.9 1.1 1.1 1.1 0.8 0.5 0.5 0.1 -0.5 -0.4 -0.5 -0.2
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 2.6 -0.9 0.0 -0.0 -1.0 -0.9 -1.2 -0.2 0.3 -0.8 -0.7 0.7 0.1 -0.4 0.0 0.1 0.1 0.3 0.3 0.7 0.5 1.6 0.5 0.4 0.5 0.2 0.3 0.2 0.5 -0.1 -0.2 0.2 -0.5 -0.7 -0.8 -1.6 -0.6 -0.8
Medication: Atenolol 0.3 0.4 2.2 -0.9 0.4 1.0 0.8 0.3 0.5 0.5 0.5 0.5 -1.0 0.3 -0.1 0.1 0.5 1.5 0.4 1.1 0.4 -0.1 0.5 -0.7 0.6 0.3 0.5 0.5 0.8 -0.2 0.2 0.6 0.0 0.8 -0.2 -0.7 -0.7 0.1 -0.8 -0.5
Medication: Levothyroxine sodium 0.4 0.8 3.2 -1.6 0.7 1.1 0.8 0.4 0.3 0.6 0.2 0.5 -1.2 0.8 0.3 0.2 0.5 -0.0 0.6 -0.1 0.7 0.7 0.8 -0.1 1.3 0.7 0.8 0.8 0.7 1.2 0.8 0.6 -0.4 0.6 -1.4 -1.8 -0.5 -0.9 -1.5 -1.7
Sitting height 0.1 1.0 18.7 0.1 -0.4 -2.0 -4.3 -0.6 -0.1 -0.2 0.3 0.7 0.2 -0.9 0.4 -0.8 -0.8 -2.5 -0.4 0.3 -0.3 -1.2 -0.3 -0.6 -0.6 -0.3 -0.3 -0.6 -0.2 -0.5 -0.1 -0.9 0.2 -0.5 0.1 0.2 -0.3 -0.5 0.2 0.1
Chronic bronchitis/emphysema (father) 1.0 1.2 4.2 -0.2 1.3 1.6 0.1 1.2 0.8 1.3 2.1 0.3 -0.4 1.2 1.5 1.2 1.4 0.1 1.1 -0.2 1.1 0.6 1.1 0.4 1.1 1.1 1.2 0.9 1.1 1.3 1.2 0.7 0.5 0.1 1.8 1.8 -0.7 0.1 1.2 1.5
High blood pressure (mother) 0.7 1.0 4.2 1.2 -1.3 -0.7 -0.0 -1.5 -1.5 -1.4 -1.2 -1.9 0.8 -0.8 -2.1 -1.5 -0.9 -0.5 -0.9 -0.2 -1.0 -0.8 -1.0 -1.0 -0.7 -1.0 -1.0 -0.8 -1.0 -1.4 -0.8 -0.6 -0.1 -0.2 -0.4 0.1 0.5 -0.4 0.6 0.1
Body mass index (BMI) 0.2 0.9 9.4 -0.9 0.5 0.6 -0.6 1.4 0.2 -0.4 -0.5 -1.3 0.4 0.4 -0.4 -0.9 -0.1 -3.1 -0.5 -2.7 0.2 -1.1 -0.2 -0.1 -0.3 0.1 -0.1 -0.6 -0.6 -0.8 -0.1 -0.5 -1.1 -1.1 -1.2 -0.7 1.1 0.0 0.3 -1.1
Impedance of leg (left) 0.1 0.4 1.9 0.2 0.2 1.0 1.4 0.6 1.2 0.3 1.0 -0.5 -0.5 0.1 0.1 0.7 0.4 1.3 0.3 0.9 0.0 1.1 -0.0 0.8 0.2 0.0 0.1 0.3 0.3 0.7 0.0 0.4 0.4 0.6 -0.2 -0.4 -0.4 0.7 -0.5 -0.2
Leg predicted mass (left) 0.1 0.7 6.6 -0.2 -0.2 -1.2 -2.2 -0.4 -0.8 -0.7 -0.7 -0.4 0.6 -0.3 -0.2 -1.1 -0.6 -2.6 -0.6 -1.2 -0.1 -1.4 -0.3 -0.6 -0.6 -0.1 -0.3 -0.6 -0.5 -1.4 -0.1 -0.7 -0.3 -0.8 -0.4 0.1 0.6 -0.5 0.5 -0.1
Trunk fat mass 0.3 1.2 9.8 -0.9 0.3 1.0 -0.0 1.5 0.8 -0.9 -0.2 -2.3 0.5 0.5 -1.0 -1.0 -0.2 -3.1 -0.6 -2.1 -0.1 -0.8 -0.5 0.3 -0.4 -0.1 -0.4 -0.8 -0.7 -1.0 -0.3 -0.6 -1.2 -1.2 -1.6 -1.1 1.3 0.5 -0.1 -1.5
Waist circumference 0.2 0.8 6.1 -1.6 0.8 1.0 -0.3 1.1 0.3 -0.1 -0.1 -1.2 -0.4 1.1 -0.8 -0.7 0.3 -2.5 0.1 -1.3 0.6 -0.0 0.4 0.4 0.3 0.6 0.4 0.0 0.2 -0.7 0.3 0.1 -0.3 -0.1 -1.3 -1.4 0.1 -0.5 -1.0 -1.9
Number of incorrect matches in round 1.2 2.0 7.0 1.7 -1.5 -0.8 2.1 -0.2 1.0 -1.7 -1.4 -2.6 2.0 -1.2 -1.9 -1.0 -1.6 -0.4 -1.6 -0.6 -1.6 0.2 -1.6 -0.4 -1.5 -1.7 -1.6 -1.6 -1.7 -1.5 -1.5 -1.4 -0.8 -1.4 -0.6 0.3 2.0 1.5 1.2 0.6
Past tobacco smoking 0.3 0.5 3.0 0.3 -0.3 0.2 0.9 0.6 0.0 -0.6 -0.1 -1.7 0.5 0.2 -1.5 -0.8 -0.2 -0.8 -0.3 -1.0 -0.5 -1.0 -0.5 -0.4 -1.0 -0.6 -0.5 -0.4 -0.5 -1.5 -0.5 -0.1 -1.0 -0.8 -0.8 -0.7 0.5 -0.1 -0.4 -0.8
Alcohol usually taken with meals 0.8 1.2 3.1 1.2 -1.4 -0.6 0.8 -0.5 -0.0 -1.4 -1.0 -1.2 1.2 -1.4 -1.8 -0.6 -1.3 0.3 -1.4 0.3 -1.5 -0.2 -1.5 -1.2 -1.6 -1.5 -1.5 -1.4 -1.2 -0.9 -1.7 -1.3 -0.8 -1.0 -0.2 0.4 0.9 1.0 1.0 0.4
Nervous feelings 1.4 2.6 7.2 -0.8 1.7 1.5 0.7 1.4 2.3 1.5 2.1 0.6 -1.3 1.5 1.6 2.2 2.2 0.9 1.8 1.7 1.4 2.7 1.2 2.1 1.8 1.5 1.3 1.8 1.3 2.4 1.6 2.3 1.9 2.1 0.7 -0.2 -0.8 0.5 -1.3 0.0
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.5 4.0 -0.4 1.3 0.1 -0.8 0.7 0.9 1.6 1.8 1.0 -0.7 1.1 1.7 1.2 0.9 0.0 1.2 0.2 1.3 0.6 1.2 2.0 1.4 1.3 1.3 1.3 1.2 1.7 1.4 1.1 1.9 1.3 1.9 1.9 -0.7 0.1 1.0 1.5
Hearing difficulty/problems with background noise 0.7 1.2 3.1 1.7 -1.3 -0.9 1.3 -1.0 -0.7 -1.5 -1.8 -1.7 1.8 -0.7 -1.1 -0.5 -1.1 0.4 -1.2 -0.5 -1.2 -0.4 -1.3 0.2 -1.1 -1.2 -1.3 -1.1 -1.5 -0.5 -1.1 -0.6 -0.4 -0.9 0.2 0.8 1.6 0.6 1.1 1.0
Hair/balding pattern: Pattern 2 2.3 2.9 6.1 1.3 -2.1 -2.5 -0.9 -1.3 -0.8 -1.8 -1.0 -1.4 1.6 -2.3 -2.0 -2.2 -2.4 -1.2 -2.3 -0.7 -2.1 -1.9 -2.2 -1.4 -1.7 -2.1 -2.2 -2.2 -2.2 -0.5 -2.1 -2.5 -1.4 -1.5 -0.8 0.2 1.3 0.4 1.4 0.1
Had menopause 1.4 1.8 5.7 -0.7 1.6 1.7 -0.0 1.3 0.8 1.6 2.0 0.4 -1.0 1.7 0.9 1.2 2.2 0.4 1.6 0.4 1.6 2.4 1.6 1.1 1.6 1.5 1.7 1.6 1.5 1.1 1.5 1.8 1.4 1.2 0.7 -0.1 -1.0 -0.3 -1.1 -0.3
Had other major operations 0.5 0.6 2.3 0.2 -0.1 0.6 1.4 0.5 0.1 -0.9 -0.4 -0.9 1.0 -0.2 0.0 0.1 -0.7 -0.9 -0.6 -1.1 -0.3 -1.1 -0.6 -0.2 -1.0 -0.3 -0.7 -0.9 -0.8 -0.9 -0.7 -0.7 -1.5 -1.5 -0.3 0.0 1.0 0.2 0.6 -0.2
Forced vital capacity (FVC) 0.3 1.0 5.8 -1.0 0.6 -0.4 -2.4 -1.0 -0.9 1.2 1.1 2.4 -0.9 0.3 1.5 -0.0 0.1 -0.1 0.8 0.3 0.9 0.5 1.1 -0.2 0.7 1.0 0.9 0.7 1.1 0.7 0.9 0.1 0.4 0.6 0.2 0.1 -1.4 -2.1 -0.2 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 4.9 -0.9 1.6 1.7 0.5 2.1 1.7 1.5 2.2 1.8 -0.7 0.9 1.4 1.7 1.2 0.4 1.1 0.0 1.1 0.6 0.9 0.9 1.1 1.0 0.9 0.8 1.1 1.6 0.9 1.0 0.6 0.3 1.0 0.6 -0.7 0.6 -0.1 0.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.3 -0.1 -0.2 -1.2 -1.0 -0.4 -0.0 -0.3 0.3 -0.7 -0.0 -0.0 -0.5 -0.9 -0.2 -1.1 -0.2 -0.7 -0.2 -0.6 -0.3 0.8 0.2 -0.1 -0.3 -0.0 -0.3 -0.0 0.2 0.0 0.2 0.3 -0.8 -0.8 0.4 -0.6 -0.5 -0.8
Qualifications: None of the above 0.7 1.5 7.2 0.5 -1.4 -1.4 1.1 -1.5 -2.0 -1.2 -1.7 -0.5 0.9 -0.9 -0.5 -1.7 -0.9 -1.0 -1.3 -0.6 -1.1 -0.8 -1.0 -2.7 -0.9 -1.0 -1.2 -1.4 -1.2 -0.6 -1.2 -1.3 -2.0 -1.3 -1.5 -1.0 0.4 -1.2 -0.2 -1.1
Financial difficulties in last 2 years 0.6 0.8 3.2 0.1 0.3 -1.8 -1.2 -1.4 -1.7 0.2 -0.4 0.1 -0.4 0.9 1.0 -0.8 0.1 -1.5 0.4 -0.3 0.8 -1.2 0.8 0.8 0.4 0.9 0.6 0.6 0.4 -0.5 0.8 0.2 1.1 1.1 1.1 1.2 -0.6 -1.4 0.7 1.2
Mouth/teeth dental problems 1.6 2.5 6.7 1.1 -1.8 -1.3 -0.3 -0.7 -0.4 -1.9 -1.5 -1.4 1.3 -2.0 -2.6 -1.7 -2.0 -0.6 -1.8 -0.1 -1.9 -2.0 -1.9 -1.4 -2.2 -1.9 -1.9 -2.1 -1.6 -2.1 -2.1 -2.0 -1.7 -1.9 -1.0 -0.4 1.0 1.0 0.7 -0.2
Heart attack 3.2 4.1 8.7 -0.4 2.4 1.8 0.3 1.9 2.3 2.0 1.5 1.2 -1.2 2.4 1.4 2.7 2.4 2.3 2.4 2.0 2.2 2.0 2.1 2.6 2.2 2.1 2.2 2.3 2.2 1.4 2.6 2.7 3.0 2.1 2.8 1.6 -1.2 1.2 -0.4 1.8
Allergy 0.2 0.5 2.2 -1.1 0.4 -0.3 -0.0 -1.0 -0.7 0.8 0.2 1.2 -1.3 0.6 0.8 -0.2 0.3 0.6 0.5 0.7 0.8 -0.2 0.9 -0.0 1.0 0.8 0.7 0.6 1.0 0.6 0.7 -0.2 0.2 0.9 0.4 0.1 -1.4 -1.5 -0.1 -0.1
Pain all over the body in last month 0.2 0.2 1.4 -0.2 0.4 -0.2 -0.8 0.4 -0.4 -0.0 0.9 -0.4 0.1 0.6 -0.0 0.1 0.3 -0.8 0.2 -1.0 0.3 0.1 0.0 1.1 0.2 0.3 0.1 0.2 -0.2 0.3 0.3 0.3 0.0 -0.1 -0.5 -0.5 0.2 -1.2 -0.6 -0.9
Diabetes (self-reported) 0.5 0.8 3.1 -0.8 -0.0 0.7 0.5 0.9 0.4 -0.3 -0.5 -0.8 0.4 -0.6 -1.4 -1.1 -0.5 -1.1 -0.6 -1.3 -0.3 -0.4 -0.5 -1.4 -0.7 -0.3 -0.6 -0.6 -0.9 -1.2 -0.7 -0.5 -1.0 -0.9 -1.8 -1.6 1.2 0.4 -0.9 -1.6
Hayfever/allergic rhinitis (self-reported) 1.1 1.5 4.6 0.5 -1.1 -1.0 -0.2 -0.3 -0.3 -1.5 -0.8 -1.5 1.3 -0.9 -2.1 -1.3 -1.1 -0.8 -1.3 -0.8 -1.3 -1.2 -1.4 -0.5 -1.7 -1.3 -1.4 -1.4 -1.5 -1.6 -1.3 -1.2 -1.5 -1.7 -1.5 -1.1 1.2 -0.0 -0.2 -1.2
Medication: Ramipril 0.8 1.1 5.1 0.6 -1.1 -0.9 -0.1 -2.1 -2.3 -1.5 -1.5 -2.0 0.3 0.0 -0.9 -1.5 -1.2 0.2 -1.0 -0.1 -0.6 -1.0 -0.4 -0.3 -0.8 -0.5 -0.5 -0.9 -0.6 -2.0 -0.4 -1.3 -0.8 -0.5 -0.6 -0.1 -0.1 -1.5 0.5 0.1
Medication: Simvastatin 0.6 0.9 6.1 -1.3 0.0 -0.5 -0.7 -1.9 -2.4 -0.1 -0.5 -0.7 -1.2 1.2 -0.9 -1.9 -0.9 0.1 0.1 -0.1 0.5 -0.9 0.7 -0.1 0.8 0.6 0.4 0.2 0.4 -0.2 0.6 -0.6 -0.4 0.2 -0.3 -0.5 -1.5 -2.5 -0.5 -0.7
Fluid intelligence score 0.9 1.9 4.4 1.1 -1.7 -1.1 -0.2 -1.3 -1.0 -1.5 -1.7 -1.1 1.1 -1.6 -1.4 -1.8 -1.9 -0.4 -1.6 0.5 -1.6 -1.7 -1.6 -2.1 -1.7 -1.6 -1.7 -1.6 -1.4 -1.8 -1.9 -1.6 -1.3 -1.1 -1.1 -0.7 0.6 0.1 0.0 -0.5
Illnesses of siblings 0.1 0.2 1.1 -0.2 0.2 -0.0 -0.4 -0.6 -0.9 0.2 0.5 -0.1 0.1 0.1 0.4 -0.4 -0.3 -0.8 -0.0 -1.1 0.3 0.0 0.3 -0.1 0.2 0.4 0.3 0.0 0.1 -0.1 0.1 -0.3 -0.2 -0.3 0.3 0.8 0.2 -1.0 1.1 0.4
Neuroticism score 0.9 1.8 5.9 -0.6 1.0 -0.4 -1.7 -0.4 0.0 1.5 1.7 1.2 -1.5 1.0 1.3 1.0 1.5 0.7 1.6 1.5 1.3 0.8 1.3 1.2 1.9 1.3 1.4 2.0 1.2 1.5 1.7 1.9 2.4 2.3 1.3 0.4 -1.1 -0.6 -0.8 0.5
Weight 0.1 0.7 9.5 -0.8 0.2 -0.2 -1.7 0.5 -0.2 -0.5 -0.3 -0.8 0.3 0.1 -0.3 -1.1 -0.4 -3.1 -0.5 -1.8 0.1 -1.2 -0.2 -0.5 -0.4 0.1 -0.2 -0.6 -0.5 -1.0 -0.1 -0.7 -0.7 -0.9 -0.9 -0.5 0.6 -0.4 0.2 -0.9
Impedance of arm (right) 0.2 1.1 6.3 0.6 -0.4 1.5 2.5 0.9 2.3 -0.9 0.1 -2.2 0.1 0.1 -1.6 0.5 -0.2 1.6 -0.3 1.7 -0.8 1.1 -0.9 1.4 -0.4 -0.8 -0.8 -0.4 -0.4 -0.1 -0.7 -0.0 -0.2 -0.0 -0.2 -0.5 0.6 2.2 -0.4 0.0
Arm fat percentage (right) 0.4 1.6 8.0 -0.9 0.2 1.5 0.7 2.0 1.4 -1.2 -0.7 -2.7 0.6 0.3 -1.5 -0.9 -0.3 -2.8 -0.8 -2.1 -0.4 -0.6 -0.8 0.4 -0.6 -0.4 -0.7 -1.0 -1.0 -0.9 -0.6 -0.6 -1.4 -1.3 -2.0 -1.6 1.8 1.3 -0.4 -1.8
Trunk fat-free mass 0.1 0.8 8.3 0.2 -0.3 -2.0 -2.9 -1.2 -1.3 0.1 -0.4 1.2 0.3 -0.6 0.6 -0.8 -0.3 -1.8 -0.1 -0.2 0.1 -1.2 0.1 -1.4 -0.4 0.2 0.1 -0.1 -0.1 -0.8 0.2 -0.4 0.4 -0.1 0.4 0.6 -0.2 -1.0 0.5 0.4
Hip circumference 0.2 0.9 9.4 -0.8 0.1 0.1 -0.8 0.6 -0.4 -0.7 -0.5 -1.4 0.6 0.2 -0.6 -1.0 -0.5 -3.1 -0.8 -2.3 -0.0 -1.2 -0.3 -0.3 -0.4 -0.0 -0.3 -0.8 -0.7 -1.0 -0.3 -0.9 -1.0 -1.2 -0.9 -0.2 1.2 -0.0 0.8 -0.7
Time employed in main current job 0.1 0.2 0.9 0.4 0.2 0.4 -0.8 0.3 0.3 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.5 0.9 0.3 0.6 0.1 0.9 0.0 0.1 -0.1 0.1 0.1 0.1 0.1 0.5 0.2 0.4 0.3 0.3 0.3 0.3 -0.1 0.3 0.0 0.6
Alcohol intake versus 10 years previously 1.1 1.7 4.2 -1.3 2.0 1.7 -0.2 1.5 0.7 1.5 0.6 0.7 -1.2 2.0 0.8 1.0 1.6 -0.9 1.6 -1.0 1.9 0.8 1.8 1.1 1.7 1.9 1.9 1.4 1.7 1.4 1.9 1.2 1.0 0.8 0.5 0.2 -0.8 -0.6 -0.4 -0.1
Father’s age at death 1.7 2.3 10.4 -1.6 1.3 1.5 0.5 0.7 1.3 1.2 1.2 0.9 -1.6 1.4 1.0 1.4 1.9 1.2 1.7 2.2 1.2 2.3 1.1 1.8 1.2 1.2 1.1 1.6 1.4 0.8 1.1 2.1 1.2 1.8 -0.8 -2.2 -1.3 0.2 -3.2 -2.1
Worrier / anxious feelings 0.2 0.4 1.4 -0.5 0.3 0.3 0.0 0.6 1.0 0.5 1.2 -0.6 -0.3 0.4 -1.2 -0.0 1.0 -0.2 0.6 0.4 0.2 0.4 0.2 0.1 0.8 0.2 0.3 0.8 0.2 0.5 0.3 1.0 1.0 0.8 0.0 -0.6 0.1 0.4 -1.2 -0.5
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 1.0 -0.1 0.2 -1.0 -0.9 -0.2 -0.4 0.1 0.0 -0.4 0.1 0.5 -0.3 -0.1 0.4 -1.0 0.2 -0.5 0.4 -0.0 0.3 0.8 0.2 0.4 0.4 0.2 0.1 0.1 0.6 0.3 0.9 0.1 -0.0 0.1 0.2 -0.2 -0.1 0.1
Falls in the last year 0.9 1.2 4.7 0.6 -0.4 0.4 0.2 1.6 2.1 -1.2 -0.6 -2.1 1.2 -0.5 -2.0 -0.1 -0.6 -1.6 -1.0 -0.8 -0.9 -0.3 -1.2 0.5 -1.2 -1.0 -1.0 -1.3 -1.1 -1.2 -1.0 -0.9 -0.3 -1.2 -0.4 0.2 1.4 2.2 0.8 0.0
Hair/balding pattern: Pattern 3 0.4 0.6 2.5 -1.3 0.6 1.1 -0.6 -0.3 -0.7 0.5 0.6 0.1 -1.0 1.0 0.5 0.1 0.6 0.2 0.8 0.5 0.8 0.8 1.0 0.2 0.4 0.8 1.0 0.7 0.9 0.1 0.8 0.6 -0.2 0.3 -0.5 -1.1 -1.3 -1.1 -1.6 -1.3
Number of live births 1.4 1.9 5.2 0.7 -1.0 -1.0 -0.8 0.4 -0.4 -1.8 -1.3 -2.3 1.6 -1.2 -1.4 -0.7 -0.8 -2.0 -1.4 -1.8 -1.3 -0.9 -1.5 -0.7 -1.8 -1.4 -1.4 -1.5 -1.9 -2.1 -1.4 -1.1 -1.5 -2.0 -1.4 -1.1 1.8 0.9 -0.4 -1.4
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 4.2 -0.8 0.9 0.2 -1.4 -0.6 -0.7 1.2 1.1 2.1 -0.9 0.6 1.6 0.6 0.5 0.9 1.1 0.4 1.2 0.8 1.2 0.5 0.9 1.2 1.1 1.1 1.1 0.3 1.1 0.7 0.8 0.9 0.6 0.4 -1.1 -1.8 -0.0 0.3
Pulse rate 0.8 1.4 5.2 -0.3 -0.1 2.3 1.9 2.0 2.2 -0.7 -0.6 -0.7 0.5 -0.8 -0.8 0.9 -0.0 0.7 -0.5 0.0 -0.7 1.6 -0.8 -0.9 -1.1 -0.7 -0.7 -0.8 -0.8 -0.7 -1.0 -0.2 -1.8 -1.5 -1.6 -1.9 1.0 1.7 -1.4 -1.6
Happiness 1.1 1.4 4.0 0.9 -1.1 -2.0 -1.3 -1.8 -1.9 -1.1 -0.8 -1.7 1.2 -0.7 -1.2 -1.8 -1.7 -1.4 -1.2 -1.7 -0.8 -0.7 -0.8 -0.2 -0.8 -0.8 -0.8 -1.1 -1.2 -0.9 -0.7 -1.4 -0.9 -1.2 -0.9 -0.1 1.2 -1.2 0.7 -0.2
Noisy workplace 0.5 0.6 2.3 0.6 0.3 0.7 0.5 -0.1 0.3 0.5 0.5 0.4 -0.4 0.5 1.0 1.0 0.7 1.1 0.8 1.2 0.5 0.9 0.6 -0.1 0.7 0.5 0.6 1.1 0.6 0.6 0.7 1.2 1.3 1.5 1.2 1.1 -0.5 -0.2 0.2 1.3
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.6 0.7 -0.3 0.4 0.1 0.3 0.6 -0.3 -0.2 -0.3 0.7 -0.3 -0.8 0.3 -0.1 0.6 -0.0 0.3 -0.5 0.8 -0.5 0.2 -0.4 -0.5 -0.5 -0.0 -0.4 0.3 -0.4 0.2 -0.1 -0.2 0.0 0.1 0.7 0.5 0.2 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 1.5 -0.4 0.4 0.1 -0.8 0.4 -0.0 0.3 -0.2 0.4 -0.0 0.0 0.8 -0.4 -0.2 -0.9 0.1 -1.2 0.3 -0.9 0.0 -0.1 -0.1 0.3 -0.0 -0.1 -0.0 0.0 0.2 -0.4 -0.5 -0.5 -0.2 -0.1 0.1 -0.0 0.4 -0.4
Mouth/teeth dental problems: Dentures 0.6 1.0 4.0 -1.4 0.8 0.3 0.7 -0.1 -0.4 1.2 1.0 1.6 -1.2 0.8 2.0 0.5 0.9 0.7 0.8 0.5 1.1 0.7 1.1 -0.3 1.5 1.0 0.9 0.9 0.9 0.8 1.0 0.8 -0.2 0.6 -0.2 -0.9 -1.2 -1.5 -1.3 -1.2
Asthma 0.6 1.3 2.5 1.6 -1.3 -1.2 -0.5 -0.1 0.4 -1.1 -0.5 -1.4 1.3 -1.5 -1.4 -0.6 -1.4 -0.9 -1.4 -0.4 -1.4 -1.0 -1.3 -1.0 -1.1 -1.5 -1.1 -1.3 -1.3 -0.5 -1.2 -1.1 -0.1 -0.9 0.2 1.0 1.2 1.6 1.5 1.1
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 2.0 1.2 0.0 0.3 0.1 -0.0 -0.0 0.2 0.1 0.4 0.5 -0.6 0.4 0.8 0.2 0.5 -0.0 0.0 0.0 -0.1 -0.0 -0.8 0.0 0.0 -0.0 -0.1 -0.1 0.4 -0.1 0.1 0.6 0.2 1.0 1.2 0.4 1.1 1.2 1.4
Medication: Cholesterol lowering 0.2 0.3 1.6 -1.3 0.2 0.5 1.2 -0.1 -0.0 -0.2 0.0 -0.7 -0.7 0.7 -0.7 -0.8 -0.7 0.6 -0.1 -0.1 0.2 -0.8 0.3 0.3 0.1 0.2 0.2 -0.2 0.2 -0.9 0.1 -0.6 -1.1 -0.4 -0.4 -0.7 -0.6 -0.4 -0.4 -0.8
Depression (self-reported) 1.5 1.8 3.8 -0.9 1.6 1.3 0.7 0.6 0.8 1.6 2.0 1.2 -1.4 1.6 1.4 1.3 1.8 1.0 1.6 1.3 1.6 1.4 1.4 1.3 1.7 1.6 1.4 1.5 1.6 1.4 1.6 1.6 1.4 1.7 1.1 0.5 -1.3 -0.3 -0.4 0.4
Medication: Lansoprazole 1.1 1.3 3.6 -1.3 0.8 0.6 -1.2 -0.7 -0.5 1.2 0.1 1.1 -1.9 1.1 0.5 -0.2 1.0 0.4 1.2 1.2 1.2 0.5 1.5 0.0 1.8 1.2 1.4 1.5 1.3 1.8 1.5 1.2 1.1 1.6 0.4 -0.4 -1.6 -1.2 -1.1 -0.2
Prospective memory result 0.3 0.4 2.1 1.0 -0.1 -0.3 1.4 0.6 0.6 -0.4 -0.1 -0.2 1.2 -0.4 -0.4 0.4 -0.0 -0.7 -0.2 -1.3 -0.3 -0.6 -0.4 -0.1 -0.3 -0.3 -0.3 -0.4 -0.6 -0.6 -0.1 0.0 -0.3 -0.9 0.2 0.7 1.4 0.8 0.9 0.8
Lung cancer (father) 1.2 1.4 4.1 1.2 -0.6 0.5 1.5 1.1 1.2 -1.4 -0.6 -1.7 2.0 -0.9 -1.2 0.0 -0.3 -1.2 -1.0 -1.3 -1.0 -0.4 -1.3 -0.4 -1.6 -1.1 -1.2 -1.4 -1.4 -1.5 -1.1 -0.7 -1.4 -1.8 -1.2 -0.5 2.0 1.1 0.3 -0.3
Illnesses of mother 0.3 0.4 2.6 0.2 0.4 -0.1 0.4 1.4 1.6 0.4 -0.1 0.9 0.5 -0.2 0.5 0.7 0.2 0.1 -0.0 -0.4 -0.0 -0.4 -0.2 0.4 -0.2 -0.1 -0.1 -0.1 -0.0 0.5 -0.2 -0.1 -0.1 -0.4 0.6 0.9 0.9 1.6 0.8 0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.8 4.7 -1.1 1.5 1.3 -0.9 -0.2 -0.6 1.7 1.8 2.2 -1.3 1.3 2.1 1.2 0.9 1.4 1.5 0.3 1.8 1.5 1.7 0.8 1.2 1.9 1.6 1.3 1.6 0.8 1.5 0.9 0.6 0.9 1.1 1.0 -1.6 -2.2 0.4 0.7
Pulse wave Arterial Stiffness index 1.6 1.9 7.8 -1.6 1.7 2.3 0.7 1.5 0.7 1.4 2.8 1.2 -1.5 1.3 2.6 2.0 1.5 1.3 1.4 0.2 1.5 1.6 1.4 0.6 1.0 1.5 1.5 1.2 1.5 -0.1 1.3 1.3 -0.1 0.6 0.5 -0.1 -1.2 -1.0 -0.5 -0.2
Impedance of arm (left) 0.3 1.3 9.0 0.5 -0.4 1.7 3.0 0.8 1.9 -1.2 -0.3 -2.8 0.3 0.1 -1.9 0.2 -0.4 1.5 -0.5 1.2 -0.9 1.1 -1.0 1.1 -0.4 -0.9 -1.0 -0.7 -0.6 -0.2 -0.9 -0.3 -0.7 -0.4 -0.5 -0.6 0.8 1.8 -0.3 -0.2
Arm fat mass (right) 0.2 0.9 9.5 -1.1 0.5 0.8 -0.7 1.5 0.8 -0.6 -0.4 -1.6 0.3 0.4 -0.7 -0.9 -0.1 -3.1 -0.4 -1.9 0.1 -0.6 -0.2 0.3 -0.3 0.1 -0.2 -0.5 -0.5 -0.9 -0.1 -0.4 -0.8 -0.9 -1.5 -1.2 1.2 0.5 -0.3 -1.4
Trunk predicted mass 0.1 0.8 7.9 0.2 -0.3 -2.0 -2.8 -1.3 -1.4 0.1 -0.4 1.3 0.3 -0.6 0.6 -0.8 -0.3 -1.8 -0.1 -0.2 0.1 -1.2 0.1 -1.4 -0.4 0.1 0.0 -0.1 -0.1 -0.8 0.2 -0.4 0.4 -0.1 0.4 0.5 -0.2 -1.1 0.4 0.4
Standing height 0.1 0.7 7.4 -0.2 -0.3 -1.7 -2.7 -1.7 -0.9 0.2 0.8 1.2 -0.6 -0.4 0.4 -0.5 -0.3 -0.4 0.2 1.6 0.2 -0.3 0.2 -0.9 0.0 0.2 0.1 0.1 0.4 -0.4 0.3 -0.3 0.8 0.5 0.5 0.3 -1.2 -1.2 -0.2 0.2
Length of working week for main job 1.3 1.4 5.4 0.2 -0.8 -1.1 -1.4 -0.1 -1.1 -1.4 -1.0 -2.1 1.0 -0.3 -1.6 -1.3 -1.1 -2.1 -1.2 -2.3 -0.9 -1.4 -0.8 -0.5 -0.9 -0.9 -0.7 -1.2 -1.1 -1.2 -0.8 -1.4 -1.4 -1.8 -0.7 0.1 1.2 -0.1 1.1 -0.2
Exposure to tobacco smoke at home 1.2 1.4 9.1 -2.0 -0.0 -0.6 -1.1 -0.6 -1.4 -0.2 -1.2 0.5 -0.7 0.1 -1.0 -1.3 0.1 -1.6 -0.1 -0.3 0.3 0.2 0.2 -1.0 0.5 0.3 0.2 -0.2 -0.0 -0.3 0.0 -0.3 -0.9 -0.5 -2.4 -2.8 -0.6 -1.7 -2.5 -3.0
Breastfed as a baby 0.5 0.6 2.7 0.6 -1.0 -1.2 -0.2 -1.5 -0.2 -0.7 -0.5 -0.8 0.4 -0.8 -1.4 -0.9 -1.1 0.2 -0.5 1.7 -0.7 0.2 -0.5 -1.6 -0.4 -0.6 -0.6 -0.2 -0.5 -1.3 -0.6 -0.3 0.6 0.6 -0.3 -0.5 0.2 0.1 -0.7 -0.2
Tense / ‘highly strung’ 0.5 0.8 6.2 -1.0 0.9 -0.4 -1.5 0.1 0.6 0.6 1.2 0.0 -0.9 1.1 -0.1 0.7 0.7 0.4 0.8 0.7 0.9 0.6 0.8 2.5 0.9 1.0 0.8 0.8 0.8 1.2 1.0 0.6 1.0 0.8 0.6 0.2 -0.7 -0.6 -0.3 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.4 -1.0 0.4 0.7 0.3 -0.2 -0.6 0.2 0.7 0.2 -0.6 0.8 1.2 0.6 0.3 0.5 0.3 -0.2 0.5 0.1 0.5 0.7 1.0 0.5 0.6 0.6 0.3 0.6 0.6 0.5 -0.1 0.5 -0.1 0.0 -0.0 -1.1 0.1 -0.1
Hair/balding pattern: Pattern 4 0.5 1.2 3.4 -0.9 1.3 1.8 0.9 0.7 -0.0 0.7 0.8 -0.5 -1.1 1.7 0.7 0.9 1.3 1.5 1.4 0.3 1.3 1.6 1.2 1.3 0.9 1.3 1.2 1.3 1.3 -0.9 1.2 1.6 0.8 1.0 0.2 -0.4 -0.7 -0.4 -1.0 -0.2
Birth weight of first child 0.2 0.4 4.5 0.7 -0.6 -0.5 -0.1 0.1 1.4 -0.0 0.4 0.5 0.1 -1.0 -0.3 -0.1 0.0 0.1 -0.3 2.1 -0.7 0.1 -0.9 -0.1 -0.6 -0.7 -0.9 -0.2 -0.3 -0.0 -0.8 0.0 0.5 0.9 0.1 -0.3 -0.2 1.2 -0.6 -0.2
Peak expiratory flow (PEF) 0.3 0.8 2.8 -0.4 0.4 -0.5 -1.7 -1.4 -1.5 0.9 0.5 1.3 -0.8 0.5 0.6 -0.3 0.2 1.1 0.8 0.5 0.9 0.7 1.0 0.1 0.7 0.9 0.9 1.0 0.8 -0.4 0.9 0.6 1.4 1.3 0.9 0.6 -0.9 -1.5 0.1 0.6
Pulse wave reflection index 0.6 0.8 4.0 0.9 -0.0 -0.9 0.2 0.3 -0.6 0.3 1.2 1.3 0.8 -0.4 2.0 1.1 0.5 -0.2 -0.1 -1.1 -0.1 -1.6 -0.1 -0.5 -0.1 -0.2 -0.0 0.1 -0.3 -0.0 -0.1 0.2 -0.0 -0.4 1.4 1.9 0.7 -0.3 1.7 1.8
Ever highly irritable/argumentative for 2 days 0.2 0.2 1.7 0.2 -0.3 -0.6 1.3 -0.2 -0.5 -0.3 0.7 -0.5 0.0 -0.1 -0.2 -0.4 0.2 -0.7 -0.3 -0.7 -0.2 -0.4 -0.4 0.2 0.2 -0.3 -0.3 -0.1 -0.2 -0.1 -0.3 0.1 -0.0 0.6 -0.5 -0.4 0.1 -1.3 -0.2 -0.5
Loud music exposure frequency 0.7 0.8 2.9 1.4 -0.7 -0.9 1.0 1.0 1.7 -0.6 0.5 -0.6 1.4 -1.2 -0.7 0.6 0.2 0.1 -0.6 0.1 -1.1 0.2 -1.1 -0.4 -1.0 -1.2 -0.9 -0.7 -0.8 -1.4 -0.9 0.1 0.1 -0.5 0.1 0.3 1.1 1.5 0.2 0.4
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.8 1.3 0.0 -0.0 -0.9 0.4 0.6 -0.1 0.4 -0.5 0.5 0.0 -0.3 0.6 0.3 0.1 0.3 0.1 -0.1 0.4 -0.1 1.0 -0.3 -0.1 0.0 0.3 0.1 -0.1 0.1 0.6 1.3 0.6 1.0 1.1 0.3 0.3 0.7 1.2
Mouth/teeth dental problems: Bleeding gums 1.3 1.6 4.0 -1.0 1.3 0.5 -1.2 -1.2 -1.1 1.4 0.4 0.5 -1.5 1.6 0.3 -0.1 0.6 0.5 1.4 0.3 1.8 1.1 2.0 0.4 1.8 1.9 1.8 1.5 1.6 1.4 1.9 0.8 1.7 1.5 0.8 0.6 -1.5 -2.0 0.0 0.8
Blood clot in the leg (DVT) 1.6 2.1 4.6 2.1 -1.9 -1.0 1.3 -0.8 -0.6 -1.8 -1.2 -1.6 1.9 -1.7 -0.3 -0.4 -1.5 -0.5 -1.8 -0.0 -1.9 -0.9 -1.9 -1.0 -1.9 -2.0 -1.8 -1.7 -1.8 -1.5 -2.0 -1.2 -1.6 -1.4 -0.3 0.8 1.4 0.7 1.6 0.9
Medication: Paracetamol 0.2 0.3 1.7 -0.1 0.7 0.6 -0.5 1.3 0.9 0.8 0.5 1.1 0.2 -0.6 -0.1 0.5 0.5 -0.2 0.3 -1.1 0.4 -1.0 0.1 -1.1 0.2 0.4 0.2 0.1 -0.1 -0.1 0.2 0.4 0.4 -0.3 0.1 0.1 0.7 0.9 0.1 0.2
Headache pain in last month 0.1 0.2 0.6 -0.6 0.7 0.4 -0.5 0.3 0.2 0.4 0.1 0.1 -0.5 0.3 0.8 0.4 0.5 0.1 0.5 -0.5 0.7 0.0 0.6 0.7 0.7 0.7 0.6 0.6 0.3 0.2 0.7 0.5 0.3 0.3 -0.3 -0.4 0.2 -0.4 -0.4 -0.3
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 4.9 1.7 -0.7 -1.8 -2.2 -0.2 -0.1 -0.3 -0.1 0.7 1.4 -1.5 1.0 0.8 -0.1 -1.3 -0.5 -0.5 -0.7 0.1 -0.8 -0.6 -0.7 -0.7 -0.6 -0.4 -0.8 0.6 -0.5 -0.1 0.6 -0.4 0.4 1.2 1.2 0.6 1.3 1.2
Glaucoma (self-reported) 1.8 2.1 5.6 0.6 -1.3 -1.5 -1.1 -1.1 -1.1 -1.8 -1.1 -2.4 1.3 -1.2 -2.3 -1.8 -1.9 -2.2 -1.5 -0.9 -1.3 -1.4 -1.3 -1.5 -1.5 -1.2 -1.3 -1.7 -1.6 -1.3 -1.2 -1.6 -1.3 -1.8 -1.6 -1.1 1.1 -0.1 -0.2 -0.9
Gout (self-reported) 1.9 2.6 6.2 0.3 -1.0 0.2 1.8 0.7 0.5 -1.5 -0.8 -2.5 1.1 -1.3 -2.5 -1.5 -1.6 -1.8 -1.6 -1.1 -1.5 -1.7 -1.7 -2.3 -1.9 -1.5 -1.8 -1.9 -1.5 -2.0 -2.0 -1.6 -2.3 -1.8 -2.1 -1.6 1.4 1.1 -0.5 -1.6
Hypothyroidism/myxoedema (self-reported) 1.7 3.4 8.0 -2.8 2.3 2.7 0.6 2.0 1.4 2.0 1.5 1.2 -2.5 2.3 0.9 1.3 2.1 0.4 2.0 -0.1 2.1 1.8 2.0 1.2 2.8 2.0 2.1 2.1 2.1 2.7 2.0 1.9 0.8 1.6 -0.6 -1.6 -1.4 -0.9 -2.0 -1.6
Medication: Amlodipine 0.2 0.3 2.1 -0.9 0.7 1.3 0.5 0.9 0.5 -0.2 -0.2 -1.0 -0.0 0.8 -1.4 -0.2 -0.2 -0.3 0.0 -0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 -0.4 -0.1 0.4 0.0 -0.5 -1.1 -1.2 -0.4 -0.4 0.2 0.1 -0.1 -0.5
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.2 0.8 -0.7 -0.7 -1.4 0.7 1.1 -0.8 -1.0 -1.1 1.2 -1.2 -1.4 -0.2 -0.8 -1.8 -0.9 -0.6 -0.9 -1.1 -0.9 -0.5 -1.1 -1.0 -0.7 -1.0 -0.9 -0.9 -0.7 -0.7 -0.3 -0.9 -0.9 -0.6 1.2 1.4 -0.2 -0.4
Birth weight 0.7 1.5 5.2 -1.6 1.8 2.1 0.2 2.3 1.2 1.4 1.5 1.4 -1.0 1.2 1.0 1.2 1.5 -0.5 1.3 -0.8 1.4 1.1 1.1 0.7 1.3 1.4 1.2 0.9 1.1 1.5 1.1 1.1 -0.4 -0.1 -0.3 -1.0 -0.5 -0.3 -1.4 -1.1
Chronic bronchitis/emphysema (mother) 1.1 1.3 3.1 -0.7 0.9 0.7 -0.6 -0.2 -0.1 1.2 0.1 0.7 -1.5 1.4 0.5 0.3 1.1 1.0 1.3 1.0 1.2 1.2 1.4 1.7 1.4 1.2 1.4 1.5 1.3 1.0 1.5 1.2 1.7 1.8 0.5 -0.3 -1.6 -1.2 -1.2 -0.2
High blood pressure (siblings) 0.1 0.2 1.8 0.2 -0.0 0.3 0.4 0.3 0.6 -0.0 -0.1 0.0 -0.4 0.2 -0.1 0.6 0.2 1.2 0.2 1.3 -0.1 0.1 -0.1 0.4 0.2 -0.1 -0.1 0.3 0.1 0.6 0.1 0.5 0.4 0.5 0.5 0.2 -0.4 0.7 -0.1 0.4
Forced vital capacity (FVC), Best measure 0.2 0.9 5.0 -0.8 0.8 0.1 -1.8 -0.6 -0.5 1.2 1.7 2.2 -0.7 0.4 1.6 0.5 0.0 0.4 0.7 0.3 1.0 0.9 1.0 0.1 0.5 1.1 0.9 0.5 1.0 0.6 0.8 -0.1 0.0 0.1 0.6 0.7 -1.4 -2.0 0.5 0.4
Body fat percentage 0.4 1.5 8.2 -1.2 0.3 1.6 0.9 1.8 1.0 -1.0 -0.1 -2.8 0.3 0.7 -1.1 -1.0 -0.2 -2.9 -0.7 -2.3 -0.2 -0.6 -0.6 0.5 -0.3 -0.2 -0.5 -0.8 -0.8 -0.9 -0.4 -0.6 -1.6 -1.2 -2.1 -1.7 1.3 0.5 -0.4 -2.0
Leg fat percentage (right) 0.3 1.0 5.8 -1.4 0.8 1.7 0.8 1.6 0.5 -0.1 -0.0 -1.9 -0.1 1.1 -0.5 -0.9 0.3 -2.4 -0.1 -2.3 0.5 -0.3 0.2 0.4 0.3 0.5 0.2 -0.1 -0.1 -0.6 0.2 0.0 -0.9 -0.4 -1.7 -1.6 0.8 -0.2 -0.7 -1.9
Arm fat-free mass (right) 0.2 0.9 8.7 -0.3 0.4 -1.5 -3.0 -0.8 -1.3 0.6 0.3 1.4 -0.1 0.1 1.3 -0.5 0.2 -2.0 0.3 -0.7 0.8 -0.8 0.7 -0.8 0.3 0.8 0.7 0.4 0.4 -0.4 0.7 0.1 0.8 0.3 0.6 0.8 -0.5 -1.6 0.6 0.5
Exposure to tobacco smoke outside home 0.8 1.1 3.8 0.7 -0.7 -0.7 -0.7 -0.7 -1.4 -0.9 -1.3 -1.4 0.8 -0.5 -1.0 -1.9 -1.5 -1.4 -1.2 -1.9 -0.6 -1.5 -0.7 -0.4 -0.6 -0.6 -0.7 -1.2 -0.9 -0.9 -0.7 -1.6 -1.1 -1.2 -0.4 0.6 0.5 -0.7 1.4 0.2
Comparative body size at age 10 0.4 1.1 3.6 -0.7 0.7 -0.3 -1.1 -0.8 -1.8 1.1 1.6 1.0 -0.9 0.9 1.9 0.4 1.2 -0.1 1.1 -0.3 1.2 -0.5 1.3 -0.2 1.2 1.2 1.3 1.4 1.0 0.2 1.1 1.0 0.9 0.8 1.3 1.0 -1.0 -1.6 0.2 0.7
Number of full brothers 1.8 2.2 4.3 1.6 -1.6 -2.1 -0.4 -0.9 -0.4 -1.8 -1.2 -1.6 1.6 -1.9 -0.7 -1.0 -1.6 -1.4 -1.7 -0.3 -1.7 -1.6 -1.9 -2.0 -2.1 -1.7 -2.0 -1.8 -1.9 -2.1 -1.6 -1.6 -1.6 -1.5 -0.8 0.0 1.2 0.6 0.9 0.1
Worry too long after embarrassment 2.1 3.6 9.7 -1.2 2.1 1.5 -0.4 0.5 0.3 1.9 1.9 0.9 -1.9 2.5 0.7 1.4 2.6 1.1 2.6 0.9 2.3 2.0 2.3 1.8 2.7 2.3 2.3 2.8 2.1 1.5 2.6 2.8 3.1 2.6 1.8 0.7 -1.4 -1.2 -0.9 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.3 -1.0 0.9 0.9 0.4 1.2 0.9 0.2 1.1 -0.3 -0.5 0.9 0.9 0.9 0.5 -0.0 0.5 -0.9 0.6 0.4 0.5 1.0 0.9 0.6 0.6 0.5 0.4 0.4 0.7 0.5 -0.1 -0.0 -0.3 -0.2 0.5 -0.1 0.0 -0.4
Wheeze or whistling in the chest in last year 1.0 1.7 6.2 2.5 -1.5 -1.0 -0.2 -0.3 -0.1 -1.6 -1.5 -2.1 1.9 -1.2 -1.4 -0.6 -1.1 -0.8 -1.4 -0.5 -1.6 -1.2 -1.7 -0.8 -1.4 -1.7 -1.5 -1.3 -1.6 -0.5 -1.4 -0.8 -0.1 -1.0 0.4 1.4 1.6 1.4 1.7 1.5
Number of children fathered 1.2 1.3 4.9 -2.0 0.9 0.4 0.3 0.2 -0.1 1.1 0.5 2.1 -1.1 1.0 1.4 0.6 0.8 -0.6 1.0 0.1 1.0 0.4 1.1 1.5 1.4 1.0 1.1 1.1 1.0 2.2 1.2 1.0 0.2 0.8 -0.8 -1.4 -0.9 -1.5 -1.8 -1.7
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 8.0 -0.5 0.4 0.5 -0.9 0.4 0.9 0.3 -0.0 0.6 -0.6 0.5 0.2 0.6 1.2 0.5 0.9 1.5 0.4 1.4 0.4 1.6 0.4 0.4 0.6 1.0 0.6 0.4 0.7 1.4 0.9 1.4 -1.1 -2.1 -0.6 -0.0 -2.8 -1.9
Age at first live birth 0.3 0.6 4.0 0.9 -0.7 0.4 2.0 0.3 1.0 -0.6 -0.6 0.4 0.8 -0.8 -0.5 0.4 -0.4 1.3 -0.5 0.8 -0.9 0.4 -0.8 -0.4 -0.8 -0.9 -0.8 -0.4 -0.5 0.5 -1.0 -0.3 -0.5 -0.2 0.3 0.6 0.6 1.1 0.7 0.9
Pulse wave peak to peak time 1.4 1.7 7.1 1.7 -1.7 -2.3 -0.8 -1.8 -0.8 -1.3 -2.7 -1.0 1.4 -1.3 -2.4 -2.0 -1.5 -1.0 -1.2 0.2 -1.4 -1.4 -1.3 -0.6 -0.9 -1.3 -1.4 -1.0 -1.3 0.2 -1.2 -1.2 0.3 -0.3 -0.2 0.3 0.9 0.9 0.6 0.4
Health satisfaction 1.7 2.3 7.3 0.8 -1.3 -1.5 -0.4 -0.2 -0.1 -1.7 -1.0 -2.7 1.3 -1.4 -2.1 -1.5 -1.1 -2.2 -1.5 -1.1 -1.4 -1.1 -1.7 -0.9 -1.5 -1.4 -1.7 -1.6 -1.9 -1.7 -1.3 -1.3 -1.3 -1.4 -2.3 -2.0 2.0 0.8 -0.9 -1.7
Shortness of breath walking on level ground 0.3 0.4 2.5 -0.0 -0.3 -0.7 -1.6 0.4 0.8 -0.3 0.2 -0.5 0.4 -0.9 -1.4 -0.4 -0.3 -0.3 -0.5 -0.2 -0.5 -0.4 -0.6 -0.3 -0.6 -0.4 -0.5 -0.7 -0.6 -0.6 -0.4 -0.5 -0.2 -0.8 -0.8 -0.7 0.7 0.6 -0.4 -0.7
Qualifications: College or University degree 0.2 0.5 3.4 0.2 -0.3 1.5 0.2 0.7 1.7 -0.3 0.1 -0.2 0.2 -0.8 -0.5 0.7 -0.6 1.3 -0.2 1.0 -0.7 1.8 -0.7 0.3 -0.5 -0.6 -0.6 -0.2 -0.4 0.4 -0.6 0.0 0.1 0.2 -0.2 -0.4 0.6 1.6 -0.2 -0.2
Eye problems/disorders: None of the above 2.3 2.6 8.2 -0.3 1.6 1.6 0.3 1.4 1.5 2.2 0.6 2.9 -1.4 0.9 2.7 2.1 1.7 2.0 1.8 1.1 1.4 2.3 1.4 1.5 1.6 1.4 1.4 1.8 1.7 2.6 1.5 1.9 1.9 2.2 1.2 0.4 -1.2 0.3 -0.7 0.6
Mouth/teeth dental problems: Loose teeth 2.8 3.4 6.7 1.9 -2.6 -2.1 0.1 -1.6 -0.7 -2.4 -1.1 -2.0 1.9 -2.4 -1.1 -1.5 -2.6 -0.8 -2.5 -0.3 -2.5 -0.9 -2.3 -2.1 -2.1 -2.5 -2.3 -2.2 -2.1 -2.2 -2.4 -2.3 -1.6 -1.4 -0.7 0.4 1.6 0.7 1.7 0.3
Emphysema/chronic bronchitis 0.2 0.3 1.6 -0.2 0.6 0.9 -0.0 0.8 0.6 0.5 0.6 -0.3 0.3 0.2 -1.2 -0.2 -0.1 -0.1 0.1 -1.3 0.4 0.1 0.3 -0.6 0.1 0.4 0.3 -0.3 0.2 -0.4 0.2 -0.4 -0.0 -1.0 0.2 0.6 0.3 0.4 0.9 0.4
Medication for pain relief, constipation, heartburn 0.3 0.4 3.5 -0.5 0.3 0.1 0.1 0.4 1.0 0.2 0.9 -0.0 -0.5 0.9 0.9 0.6 0.4 -0.1 0.5 0.9 0.2 1.6 0.3 1.9 0.4 0.2 0.4 0.6 0.7 1.0 0.5 0.4 0.4 0.5 0.5 0.2 -0.6 -0.2 -0.3 -0.0
Neck or shoulder pain in last month 0.2 0.3 1.2 0.8 -0.3 -0.7 -0.6 -1.1 -0.7 0.1 -0.3 0.3 0.0 -0.5 0.1 -0.5 -0.4 0.9 -0.0 0.7 -0.0 -0.3 -0.2 -0.0 -0.2 0.1 -0.3 0.0 -0.2 -0.2 -0.2 -0.2 0.7 0.9 0.4 0.6 -0.3 -0.6 0.7 0.7
Medication: Blood pressure 0.5 0.9 8.3 -1.0 0.8 2.3 2.9 0.6 0.3 0.2 0.1 -0.9 -1.1 1.4 -1.1 -0.2 0.5 1.9 0.6 0.7 0.7 0.7 0.7 0.8 0.6 0.7 0.5 0.6 0.8 -0.9 0.4 0.5 -0.1 0.8 -0.1 -0.7 -0.9 -0.2 -1.0 -0.7
Angina (self-reported) 1.8 2.4 5.1 -1.7 2.0 2.1 1.3 1.1 0.4 1.7 0.5 1.4 -2.0 2.3 1.1 1.0 1.5 1.6 1.6 0.7 2.0 1.0 2.0 1.3 2.1 1.9 1.9 1.6 2.1 1.4 1.7 1.2 1.1 1.6 1.7 1.2 -2.1 -0.4 0.4 1.0
Migraine (self-reported) 1.0 1.2 5.4 1.7 -1.1 -1.7 1.0 -1.9 -1.6 -0.7 -1.0 0.1 0.8 -0.9 0.5 -0.2 -1.3 1.0 -0.9 0.0 -0.7 -2.0 -0.6 -0.5 -0.5 -0.7 -0.7 -0.7 -0.6 -0.2 -0.7 -1.2 -0.1 -0.0 1.2 2.0 0.1 -0.1 2.3 1.9
Medication: Ibuprofen 0.4 0.4 2.5 1.1 0.1 0.2 -0.0 0.3 0.0 0.4 0.1 0.9 0.5 -0.7 0.5 0.9 0.0 0.4 -0.1 -0.4 0.0 -0.2 -0.1 -0.7 0.1 0.1 -0.1 -0.3 -0.2 0.9 -0.3 -0.1 0.4 0.0 1.1 1.5 0.4 1.1 1.6 1.6
Medication: Allopurinol 1.4 1.8 8.2 1.3 -0.8 1.0 2.7 1.2 1.7 -1.2 -0.9 -2.2 1.1 -1.2 -2.0 -0.5 -0.9 0.0 -1.0 0.5 -1.4 -0.5 -1.6 -1.4 -1.6 -1.4 -1.7 -1.3 -1.2 -1.4 -1.7 -0.6 -1.0 -0.9 -0.7 -0.7 1.4 2.9 -0.4 -0.3
Medication: Omeprazole 0.9 1.1 6.0 0.8 -1.0 -0.3 1.1 -0.2 -0.1 -1.5 -0.5 -2.4 1.1 -0.5 -1.6 -1.2 -0.9 -1.0 -1.2 -0.8 -1.1 -0.7 -1.3 -0.0 -1.1 -1.2 -1.3 -1.2 -1.3 -1.6 -1.0 -0.8 -1.1 -1.0 -0.9 -0.4 1.1 0.6 0.2 -0.5
Medication: Seretide 50 evohaler 0.2 0.3 1.6 0.7 -0.2 -0.4 -1.1 0.2 0.2 -0.3 0.2 -1.0 0.6 -0.3 -0.6 0.2 0.1 -1.3 -0.1 -0.4 -0.2 -0.3 -0.2 -0.8 -0.4 -0.2 -0.0 -0.1 -0.4 -0.4 -0.0 0.2 0.5 -0.5 0.5 0.7 0.6 0.8 0.5 0.7
Mean time to correctly identify matches 0.5 0.9 5.0 1.3 0.1 0.7 2.2 1.1 1.3 -0.1 0.2 -1.1 1.5 -0.1 -0.7 0.1 0.1 0.4 -0.4 -0.7 -0.3 -0.6 -0.6 -0.3 -0.6 -0.3 -0.6 -0.7 -0.7 -1.0 -0.5 -0.6 -0.4 -1.2 0.9 1.6 1.2 1.6 1.5 1.4
Heart disease (mother) 0.7 0.8 2.9 -0.6 0.8 0.8 -0.4 0.0 -0.0 0.9 0.9 0.6 -1.2 0.9 1.0 0.6 0.8 0.1 0.9 1.2 1.0 1.2 1.0 0.3 1.2 1.0 1.0 0.8 1.2 1.1 1.0 0.8 1.1 1.1 0.9 0.6 -1.7 -0.3 -0.0 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 2.5 -0.1 -0.7 -0.4 0.3 -1.4 -0.9 -0.7 -1.6 -0.8 -0.3 -0.2 -1.4 -0.9 -0.7 0.3 -0.5 0.8 -0.4 0.5 -0.2 -0.5 -0.6 -0.4 -0.3 -0.4 -0.1 -0.8 -0.5 -0.7 -0.2 0.1 -0.7 -0.8 -0.5 0.1 -0.4 -0.5
Whole body fat mass 0.2 1.0 8.6 -1.1 0.4 1.0 0.1 1.4 0.6 -0.7 -0.1 -1.9 0.3 0.5 -0.6 -0.9 -0.0 -2.9 -0.5 -2.0 0.1 -0.7 -0.3 0.3 -0.3 0.0 -0.3 -0.6 -0.6 -1.0 -0.2 -0.4 -1.1 -1.0 -1.6 -1.2 1.1 0.2 -0.3 -1.6
Leg fat mass (right) 0.2 0.7 7.1 -1.0 0.5 0.8 -0.1 1.2 0.3 -0.4 -0.4 -1.6 0.1 0.7 -0.4 -0.9 0.1 -2.7 -0.3 -1.9 0.3 -0.7 -0.1 0.2 -0.1 0.2 -0.0 -0.3 -0.3 -0.9 0.0 -0.2 -0.7 -0.5 -1.3 -1.1 0.8 -0.0 -0.4 -1.4
Arm predicted mass (right) 0.2 0.9 8.4 -0.5 0.5 -1.3 -2.9 -0.9 -1.5 0.7 0.4 1.4 -0.3 0.3 1.3 -0.5 0.4 -1.9 0.5 -0.7 0.9 -0.6 0.9 -0.8 0.5 1.0 0.9 0.6 0.6 -0.2 0.9 0.2 0.8 0.4 0.6 0.7 -0.7 -1.8 0.3 0.2
Pulse rate, automated reading 0.4 1.1 9.8 -0.5 0.7 2.7 3.1 2.4 2.1 -0.3 -0.3 -0.8 0.2 0.2 -0.9 1.0 0.4 0.6 0.0 -0.8 0.1 0.9 -0.2 0.2 -0.5 0.0 -0.2 -0.4 -0.3 -0.8 -0.3 0.0 -1.4 -1.1 -0.9 -1.2 0.7 1.0 -0.9 -1.0
Alcohol intake frequency. 0.6 1.5 8.4 -1.4 1.7 1.2 0.7 2.9 1.6 0.8 1.2 -0.2 -0.1 1.6 1.0 1.3 1.7 -2.6 1.0 -2.5 1.1 0.4 0.9 1.4 0.7 1.0 1.1 0.8 0.6 0.5 1.1 1.2 -0.1 -0.6 -0.3 -0.5 0.6 0.1 -0.8 -1.0
Comparative height size at age 10 0.1 0.4 1.0 -0.2 0.5 -0.6 -0.8 -0.1 0.3 0.5 0.8 1.0 -0.0 0.6 0.5 0.6 0.8 -0.7 0.7 0.5 0.6 0.3 0.7 0.4 0.4 0.6 0.7 0.6 0.6 0.7 0.9 0.6 0.9 0.1 1.0 0.6 -0.4 -0.2 -0.1 0.6
Number of full sisters 1.2 1.5 3.4 1.0 -1.0 -1.7 -0.8 -0.1 -0.4 -1.0 -1.3 0.0 1.6 -1.8 -0.4 -0.2 -1.2 -1.0 -1.5 -1.3 -1.2 -1.5 -1.4 -1.7 -1.5 -1.2 -1.3 -1.7 -1.5 -0.8 -1.5 -1.5 -1.4 -1.8 -0.6 0.4 1.3 0.6 1.3 0.2
Suffer from ‘nerves’ 1.9 2.9 6.8 -1.2 1.8 1.1 0.2 0.8 1.4 1.9 2.2 1.5 -1.8 1.6 1.7 1.7 2.1 1.2 2.1 1.9 1.8 1.7 1.7 2.0 2.3 1.8 1.7 2.4 1.7 1.4 2.0 2.5 2.4 2.6 1.0 -0.3 -1.2 0.2 -1.7 -0.1
Overall health rating 0.2 0.5 2.5 -0.6 0.3 -0.6 -1.4 -0.3 -0.4 0.0 -0.1 -0.8 -0.3 0.7 -0.9 -0.8 0.4 -1.5 0.3 0.2 0.4 -0.1 0.3 -0.2 0.4 0.4 0.3 0.4 0.1 0.2 0.5 0.5 0.7 0.6 -0.8 -1.2 -0.4 -0.5 -1.6 -1.3
Chest pain or discomfort 0.3 0.4 2.2 -0.6 0.5 0.3 0.5 -0.6 -0.8 0.3 0.6 0.1 -0.9 0.8 0.8 0.3 0.2 0.5 0.3 0.1 0.6 0.2 0.5 0.8 0.9 0.7 0.4 0.4 0.5 1.5 0.4 0.2 0.3 0.9 0.7 0.7 -0.9 -1.1 0.4 0.2
Had major operations 1.7 2.0 8.9 -2.1 2.0 3.0 1.2 2.5 2.4 1.2 1.7 0.3 -1.0 1.8 0.8 1.7 1.1 0.1 1.3 -0.0 1.6 1.6 1.2 2.0 0.8 1.6 1.3 0.8 1.2 0.2 1.2 1.0 -0.0 -0.2 -0.6 -1.3 -0.5 0.5 -1.5 -1.5
Age at last live birth 0.2 0.3 1.1 0.9 -0.5 -0.3 0.4 0.4 0.3 -0.4 -1.0 -0.0 0.6 -0.8 -0.7 0.2 -0.2 0.1 -0.5 0.2 -0.7 0.4 -0.7 0.3 -0.5 -0.7 -0.6 -0.4 -0.6 0.7 -0.7 -0.1 -0.1 0.0 0.1 0.1 0.6 0.7 -0.1 0.3
Family relationship satisfaction 1.7 2.1 6.8 -0.6 1.7 1.4 -0.4 0.9 0.9 1.4 2.6 0.5 -1.3 1.6 1.5 1.9 1.7 1.5 1.8 1.4 1.5 1.2 1.4 1.8 1.4 1.6 1.5 1.7 1.5 0.6 1.7 2.0 1.9 1.6 1.5 0.5 -1.2 -0.3 -0.8 0.6
Leg pain on walking 1.2 1.5 5.5 -0.7 -0.6 -0.7 -0.8 0.7 0.9 -0.8 0.5 -1.4 0.6 -1.0 -1.5 -0.9 -0.4 -2.3 -0.8 -0.9 -0.9 -1.2 -1.0 -0.5 -1.2 -0.9 -1.0 -0.9 -1.1 -1.9 -1.0 -0.7 -1.1 -1.3 -2.2 -2.3 1.4 0.2 -1.6 -2.3
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 4.5 1.0 0.3 -0.1 0.4 0.5 0.9 0.5 1.0 0.7 0.0 0.1 1.6 1.4 0.6 0.7 0.5 0.7 0.2 -0.2 0.3 -0.1 0.4 0.2 0.4 0.8 0.5 0.2 0.5 1.0 1.4 1.1 2.1 2.0 -0.2 0.9 1.1 2.1
Commuting to job workplace: Car/motor vehicle 0.8 0.9 4.9 1.1 -0.7 -2.0 -1.4 -1.5 -1.3 -0.3 -0.2 -0.2 0.6 -0.4 0.2 -0.8 -0.6 -0.8 -0.5 -0.4 -0.3 -0.5 -0.3 -0.3 -0.1 -0.3 -0.3 -0.3 -0.4 0.0 -0.2 -0.7 0.8 0.1 1.3 2.2 0.3 -0.1 2.2 2.0
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.6 0.6 -0.5 0.9 0.4 1.0 1.6 -0.2 1.1 -0.1 0.4 -1.0 -0.8 1.1 0.2 1.2 -0.2 1.4 -0.8 1.3 -0.7 -0.6 -0.6 -0.9 -0.5 -0.3 -0.3 0.2 -0.7 0.3 -0.0 -0.5 -0.2 -0.6 0.3 1.3 -0.9 -0.3
Medication: Aspirin 1.2 1.6 6.2 -1.3 0.9 -0.2 -1.6 -1.7 -2.5 1.1 -0.1 0.3 -1.9 1.5 -0.0 -1.1 0.7 0.6 1.2 0.5 1.6 -0.2 1.7 0.3 1.4 1.6 1.6 1.4 1.4 -0.1 1.5 0.8 1.3 1.6 0.8 0.2 -2.2 -2.4 -0.3 0.2
Supplements: Vitamin C 1.7 2.0 5.4 -0.3 1.2 0.5 -0.8 -0.5 -0.4 1.5 1.5 0.4 -1.5 1.7 0.9 0.4 1.4 1.4 1.8 1.4 1.6 1.5 1.6 1.2 1.7 1.6 1.5 2.1 1.6 0.5 1.8 1.8 2.3 2.3 1.8 1.0 -1.8 -1.6 -0.4 0.9
Knee pain experienced in last month 0.2 0.3 1.6 0.4 -0.2 -0.2 0.2 0.2 -0.1 -0.4 -1.2 -0.7 0.8 -0.1 -0.9 -0.6 0.4 -0.5 0.0 -0.8 -0.3 -0.4 -0.5 -0.9 -0.6 -0.3 -0.5 0.1 -0.7 -0.8 -0.2 0.3 -0.3 -0.4 -0.5 -0.6 1.0 0.2 -0.7 -0.6
Hypertension (Self-reported) 0.8 2.1 10.4 -2.5 0.5 1.9 2.1 -0.2 -0.9 -0.1 0.5 -1.2 -1.4 1.2 -2.1 -1.8 -0.4 0.8 0.1 -0.3 0.6 0.9 0.6 -0.9 0.5 0.7 0.3 0.0 0.4 -1.8 0.2 -0.5 -1.4 -0.0 -2.5 -3.1 -1.0 -2.5 -2.6 -3.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 4.4 -1.3 1.0 1.0 0.1 0.3 -0.3 0.7 -0.6 0.6 -1.0 1.3 -0.4 -0.3 0.9 -0.2 1.0 -0.3 1.1 1.1 1.0 0.9 1.1 1.1 0.9 0.8 0.9 1.0 1.2 1.0 0.3 0.8 -1.0 -1.6 -0.8 -1.2 -2.1 -1.7
Illnesses of father: Heart disease 0.6 0.8 4.6 0.4 -0.3 -0.2 -0.0 -1.3 -0.8 0.4 0.1 0.9 -0.6 0.2 0.5 0.3 0.7 1.6 0.5 2.1 0.2 0.9 0.3 0.1 1.2 0.1 0.3 0.9 0.5 0.9 0.3 1.0 2.0 2.1 1.1 0.6 -1.0 -0.4 -0.5 0.7
Illnesses of siblings: Diabetes 1.3 1.6 5.9 -0.9 1.6 2.0 1.0 2.4 2.0 1.1 0.4 0.8 -1.0 1.6 0.7 1.9 1.8 1.4 1.4 0.4 1.1 1.5 1.1 2.1 0.7 1.0 1.2 1.2 1.2 0.7 1.2 1.7 0.6 0.7 0.2 -0.7 -0.7 0.8 -1.3 -0.3
Smoking status: Previous 1.0 1.5 4.5 -0.3 0.5 -0.0 -0.2 -1.2 -0.5 1.2 0.4 2.1 -1.3 0.5 1.6 0.7 0.7 1.8 1.0 2.1 1.0 1.4 1.2 0.3 1.5 1.0 1.1 1.2 1.4 1.6 1.1 0.9 1.9 2.1 1.5 1.0 -1.7 -0.7 0.0 1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 3.0 0.1 -1.1 -1.0 -1.7 -1.3 -1.4 -1.4 0.1 -1.3 0.4 -1.0 -1.0 -1.1 -1.4 -1.1 -1.2 -0.4 -1.1 -0.7 -1.1 -1.0 -1.4 -1.0 -1.1 -1.2 -1.0 -1.6 -1.1 -1.4 -1.3 -1.1 -1.2 -0.6 0.3 -1.5 0.3 -0.7
Whole body fat-free mass 0.1 0.7 7.7 -0.1 -0.1 -1.6 -2.8 -0.8 -1.1 -0.1 -0.4 0.7 0.3 -0.4 0.5 -0.8 -0.3 -2.2 -0.2 -0.6 0.1 -1.2 0.1 -1.0 -0.4 0.2 0.1 -0.2 -0.2 -0.9 0.2 -0.4 0.2 -0.3 0.2 0.5 0.0 -0.9 0.5 0.2
Leg fat-free mass (right) 0.1 0.6 6.9 -0.2 -0.1 -1.2 -2.4 -0.1 -0.5 -0.5 -0.6 -0.1 0.6 -0.3 -0.2 -0.7 -0.5 -2.6 -0.5 -1.2 -0.1 -1.3 -0.3 -0.4 -0.6 -0.1 -0.2 -0.6 -0.5 -1.0 -0.1 -0.6 -0.2 -0.9 -0.3 0.1 0.6 -0.3 0.5 -0.1
Arm fat percentage (left) 0.5 1.9 8.6 -0.7 0.2 1.6 1.1 2.2 1.3 -1.3 -0.9 -2.9 0.9 0.3 -1.5 -0.9 -0.4 -2.9 -0.9 -2.5 -0.5 -0.7 -0.9 0.3 -0.7 -0.5 -0.8 -1.1 -1.2 -1.0 -0.8 -0.7 -1.7 -1.5 -2.0 -1.4 2.1 1.3 -0.0 -1.6
Average weekly red wine intake 0.7 1.1 4.5 -0.2 0.6 1.6 1.0 -0.5 -0.2 1.0 0.1 0.8 -0.7 1.0 -0.0 0.2 0.3 1.3 0.6 1.1 0.9 1.9 0.9 -0.4 1.1 0.9 0.8 0.4 1.1 2.1 0.7 -0.0 0.6 0.4 1.8 2.1 -1.3 0.3 1.5 1.8
Handedness (chirality/laterality): Left-handed 1.2 1.4 5.2 -0.7 1.2 0.3 -0.7 0.7 0.6 1.3 1.7 2.0 -0.8 1.0 2.3 1.7 1.6 0.6 1.2 0.6 1.1 0.1 1.0 1.7 1.2 1.1 1.1 1.3 1.0 1.7 1.3 1.5 1.6 1.2 1.5 1.0 -0.7 0.2 -0.2 0.8
Mood swings 0.5 0.8 3.8 -1.2 0.1 -1.1 -1.6 -1.5 -1.1 1.0 0.6 1.9 -1.4 -0.2 0.8 -0.6 -0.3 0.3 0.4 0.9 0.6 -0.2 0.7 -0.3 0.9 0.7 0.6 0.7 0.7 0.5 0.6 0.0 0.6 1.4 -0.4 -0.6 -1.3 -1.7 -0.7 -0.6
Loneliness, isolation 1.1 1.5 3.7 -1.2 1.1 -0.1 -1.5 -0.2 -0.3 1.3 1.2 0.7 -1.4 1.7 1.0 0.2 1.2 -0.4 1.5 0.4 1.4 0.9 1.5 1.7 1.7 1.4 1.5 1.8 1.3 1.0 1.8 1.5 1.9 1.6 0.7 -0.2 -1.2 -0.8 -1.1 -0.2
Long-standing illness, disability or infirmity 0.7 1.1 3.4 -0.9 1.4 1.4 0.6 0.9 0.5 1.0 0.8 -0.8 -1.3 1.9 -0.3 0.3 1.3 -0.2 1.3 0.2 1.4 0.8 1.4 1.2 1.3 1.4 1.4 1.2 1.3 0.4 1.5 1.3 1.2 1.0 0.4 -0.2 -1.1 -0.3 -0.7 -0.0
Ever had bowel cancer screening 1.8 2.1 4.5 -0.2 1.2 1.1 -0.4 -0.3 -0.1 1.4 1.2 1.0 -1.1 1.8 1.4 1.3 1.6 1.5 1.7 2.0 1.6 1.8 1.7 0.7 1.4 1.6 1.7 1.6 1.9 1.0 1.6 1.7 2.0 1.7 2.1 1.5 -2.1 -0.6 0.1 1.5
Diabetes diagnosed by doctor 0.4 0.7 2.6 -0.5 0.0 0.8 0.9 1.0 0.5 -0.4 -0.7 -0.8 0.5 -0.3 -1.2 -0.8 -0.3 -0.8 -0.5 -1.4 -0.2 -0.4 -0.4 -1.0 -0.5 -0.3 -0.4 -0.5 -0.7 -1.0 -0.5 -0.4 -1.1 -0.9 -1.6 -1.5 1.2 0.3 -0.8 -1.4
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.1 3.9 1.6 -1.1 -1.4 0.1 -0.5 -0.1 -0.9 -1.3 -0.1 1.4 -1.5 -0.7 -0.1 -0.9 -0.0 -1.3 0.1 -1.1 -0.7 -1.1 -1.3 -1.0 -1.1 -1.1 -1.4 -1.1 0.1 -1.1 -1.2 -0.4 -0.9 0.9 1.7 0.6 1.3 2.0 1.6
Friendships satisfaction 0.3 0.4 2.5 -0.4 0.0 0.3 -0.0 -0.0 0.1 -0.3 1.0 -1.6 -0.1 0.4 -0.1 0.1 0.3 -0.4 0.2 -0.2 0.0 0.7 0.0 1.1 0.3 0.0 0.1 0.5 -0.3 0.7 0.4 0.7 0.0 0.2 -0.9 -1.3 0.6 -1.0 -1.3 -1.2
Qualifications: nursing, teaching 0.3 0.5 2.3 -1.4 0.6 1.4 1.5 -0.1 -0.4 0.3 0.9 -0.1 -0.8 0.8 -0.5 -0.1 -0.1 0.1 0.4 0.2 0.7 1.5 0.5 0.1 0.4 0.8 0.4 0.2 0.6 -0.2 0.2 0.1 -0.5 0.3 -0.9 -0.9 -0.8 -1.1 -0.7 -1.2
Commuting to job workplace: Walk 0.5 0.6 2.5 -0.8 0.8 1.0 -0.1 0.9 0.5 0.7 0.9 0.4 -0.6 0.7 0.2 0.6 0.5 1.0 0.8 0.2 0.6 0.7 0.7 1.6 0.5 0.6 0.7 0.7 0.6 0.0 0.8 1.0 0.2 0.3 -0.4 -1.0 -0.6 -0.8 -1.4 -1.0
Eye problems/disorders: Cataract 0.1 0.1 1.3 0.2 -0.2 -0.2 0.3 -0.1 0.2 -0.5 -0.1 -0.9 0.2 0.2 -1.1 -0.3 0.1 -0.5 -0.1 0.6 -0.2 -0.7 -0.3 -0.1 -0.4 -0.2 -0.3 -0.1 -0.4 -0.7 -0.2 0.1 0.0 -0.2 0.1 -0.1 -0.0 0.1 -0.3 -0.1
Mouth/teeth dental problems: Mouth ulcers 3.0 4.8 11.2 -2.1 2.5 2.5 -0.0 2.8 2.0 2.2 1.8 1.6 -1.9 2.7 1.9 2.4 3.2 -0.5 2.5 0.1 2.1 2.2 2.0 3.4 2.5 2.0 2.2 2.7 2.1 2.7 2.4 3.2 2.5 2.6 0.3 -1.2 -1.1 -0.0 -2.8 -1.3
Medication for cholesterol 0.2 0.3 1.7 0.4 -0.1 -0.6 -0.9 0.1 0.9 0.3 -0.4 1.1 -0.0 -0.2 0.2 0.4 0.0 -0.2 0.1 0.9 -0.0 0.2 0.2 0.7 -0.1 -0.1 0.3 0.1 0.5 0.4 0.2 0.1 0.8 0.4 0.8 0.7 -0.4 1.3 0.2 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.0 3.2 -0.6 0.5 -1.0 -1.7 -1.5 -1.8 1.0 0.1 1.1 -1.0 0.8 1.0 -0.9 0.2 -0.6 0.9 -0.1 1.1 -1.0 1.2 -0.5 1.2 1.2 1.0 1.1 0.9 0.3 1.1 0.4 1.1 0.9 1.1 1.0 -1.1 -1.6 0.6 1.0
Back pain experienced in last month 0.4 0.5 2.4 1.0 0.0 -0.9 -0.8 -0.0 -0.5 -0.1 -0.6 -0.9 0.4 0.2 -0.3 -0.6 0.2 -1.4 -0.1 -0.7 0.1 -1.5 -0.0 -0.9 0.0 0.0 0.0 -0.1 -0.2 -0.4 -0.0 -0.0 0.6 -0.1 1.1 1.5 0.2 0.7 1.5 1.5
Mineral and other dietary supplements 0.2 0.3 2.3 -0.5 0.2 1.1 1.5 0.4 0.1 -0.2 -0.1 -0.8 -0.4 0.5 0.0 -0.1 -0.1 1.0 -0.1 -0.2 0.0 0.3 -0.0 0.8 0.0 0.1 -0.1 -0.3 0.1 -0.1 -0.2 -0.4 -0.9 -0.4 -0.7 -0.7 -0.1 0.0 -0.4 -0.8
Breast cancer (self-reported) 0.1 0.2 1.1 -0.0 0.2 -0.2 0.5 0.8 0.2 0.2 0.3 0.5 0.2 -0.2 0.4 0.3 0.1 -0.1 -0.3 -0.8 0.0 -0.2 -0.2 0.3 -0.3 -0.1 -0.1 -0.6 0.0 0.0 -0.3 -0.3 -1.0 -0.7 -0.4 -0.1 -0.3 -0.0 0.1 -0.6
Asthma (self-reported) 0.5 1.0 2.3 1.4 -1.2 -1.2 -0.9 -0.1 0.4 -0.9 -0.4 -1.2 1.1 -1.4 -1.3 -0.5 -1.2 -0.9 -1.2 -0.2 -1.3 -0.9 -1.1 -0.9 -1.0 -1.4 -1.0 -1.0 -1.1 -0.3 -1.0 -0.9 0.1 -0.7 0.2 0.9 1.0 1.5 1.3 1.1
Osteoporosis (self-reported) 0.6 0.8 4.4 1.3 -0.6 0.3 1.3 -0.4 1.3 -0.1 -0.3 0.6 0.5 -1.0 0.1 0.6 -0.2 1.8 -0.2 2.1 -0.6 0.2 -0.5 -0.7 0.1 -0.6 -0.5 0.1 -0.3 0.8 -0.4 0.3 0.8 0.8 1.0 1.1 0.5 2.0 0.6 1.5
Osteoarthritis (self-reported) 2.2 2.8 6.6 -1.3 2.2 1.8 -0.3 1.3 0.8 2.2 2.1 1.1 -1.3 2.4 1.1 1.5 2.6 0.5 2.2 0.3 2.2 1.7 2.2 1.4 1.9 2.1 2.3 2.2 1.9 1.5 2.2 2.2 1.8 1.2 1.5 0.9 -1.2 -0.5 -0.4 0.8
Medication: Aspirin 0.6 0.8 3.5 -0.8 0.5 -0.4 -1.4 -1.3 -1.9 0.7 -0.3 0.2 -1.3 0.9 -0.3 -1.1 0.3 0.6 0.7 0.5 1.0 -0.5 1.2 0.1 0.9 1.1 1.1 0.9 1.0 -0.2 1.0 0.4 1.1 1.2 0.9 0.5 -1.6 -1.6 0.0 0.5
Medication: Gliclazide 1.0 1.1 4.3 -1.2 -0.6 -0.8 -0.3 -1.5 -2.0 -0.4 -1.4 -0.1 -0.5 0.1 -1.0 -2.1 -1.1 -1.1 -0.7 -0.5 -0.2 -1.3 -0.1 -1.0 0.2 -0.1 -0.3 -0.6 -0.2 -0.3 -0.4 -1.2 -1.0 -0.2 -1.7 -1.8 -0.6 -1.5 -1.3 -2.0
Illnesses of father: None of the above (group 1) 0.4 0.5 1.9 0.5 -0.1 -0.2 0.1 1.1 1.2 -0.5 -0.2 -0.7 1.0 -0.6 -0.4 0.1 -0.3 -1.3 -0.5 -1.1 -0.5 -0.1 -0.6 0.4 -1.1 -0.5 -0.6 -0.8 -0.7 -0.7 -0.4 -0.4 -1.0 -1.4 -0.8 -0.5 1.0 0.8 0.2 -0.4
Smoking status: Current 2.1 3.3 8.8 1.5 -1.3 -1.7 -1.7 0.9 0.9 -1.9 -1.4 -1.5 2.6 -2.2 -0.9 -0.2 -1.5 -2.6 -2.1 -2.4 -1.9 -1.9 -2.0 -0.4 -2.2 -1.9 -1.8 -2.3 -2.3 -0.8 -1.8 -1.9 -1.9 -2.9 -1.3 -0.1 3.0 2.2 1.4 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.3 1.8 -0.5 0.4 1.2 1.3 0.4 0.5 0.6 1.1 1.1 -0.4 0.2 1.1 0.5 -0.1 0.7 0.2 0.5 0.4 0.6 0.4 0.3 0.4 0.4 0.3 0.1 0.5 0.6 0.1 0.1 -0.6 0.1 0.2 0.1 -0.6 -0.9 0.1 -0.1
Whole body water mass 0.1 0.7 8.1 0.0 -0.2 -1.8 -2.9 -1.0 -1.2 -0.1 -0.4 0.7 0.4 -0.4 0.5 -0.8 -0.4 -2.2 -0.2 -0.7 0.1 -1.3 0.1 -1.0 -0.4 0.2 0.0 -0.2 -0.2 -1.0 0.2 -0.5 0.3 -0.3 0.2 0.5 0.1 -1.0 0.6 0.3
Leg predicted mass (right) 0.1 0.7 7.1 -0.2 -0.2 -1.2 -2.4 -0.1 -0.5 -0.6 -0.7 -0.2 0.7 -0.4 -0.2 -0.8 -0.5 -2.7 -0.5 -1.2 -0.2 -1.3 -0.3 -0.4 -0.6 -0.1 -0.3 -0.7 -0.6 -1.1 -0.1 -0.7 -0.3 -0.9 -0.3 0.1 0.7 -0.3 0.5 -0.1
Arm fat mass (left) 0.3 1.1 8.8 -0.6 0.2 0.9 -0.2 1.6 0.8 -0.9 -0.7 -1.9 0.8 0.1 -0.8 -0.8 -0.2 -3.0 -0.7 -2.2 -0.2 -0.8 -0.6 -0.0 -0.5 -0.2 -0.5 -0.8 -0.9 -1.0 -0.4 -0.6 -1.1 -1.2 -1.4 -0.9 1.6 0.8 0.2 -1.1
Number of self-reported non-cancer illnesses 0.4 0.7 2.5 -1.0 0.9 1.3 0.5 0.2 -0.1 0.6 0.4 -0.7 -0.9 1.6 -0.6 -0.1 0.8 0.1 0.9 0.3 1.1 0.2 1.1 0.6 1.0 1.1 1.1 0.8 0.9 0.3 1.2 0.8 0.3 0.4 -0.5 -0.9 -0.9 -0.7 -1.3 -0.8
Average weekly champagne plus white wine intake 0.3 0.4 2.5 0.8 0.2 0.5 0.4 1.4 1.6 -0.3 0.1 -0.3 1.0 -0.3 -0.4 1.0 0.3 -0.8 -0.2 -0.9 -0.3 0.1 -0.5 -0.1 -0.7 -0.3 -0.4 -0.5 -0.4 -0.2 -0.3 -0.1 -0.1 -0.7 -0.2 0.2 1.1 1.2 0.6 0.3
Miserableness 0.5 0.9 2.9 -0.8 0.7 -0.7 -1.6 -0.5 -0.7 1.2 0.6 1.7 -0.9 0.5 1.5 0.3 0.7 -0.2 0.9 -0.1 0.9 -0.6 1.0 0.8 1.4 1.0 1.0 1.2 0.7 0.8 1.2 1.0 1.3 1.4 -0.2 -0.5 -0.5 -0.8 -1.0 -0.4
Guilty feelings 0.5 0.8 3.2 -0.8 -0.1 -1.1 -1.8 -1.7 -1.2 0.5 0.4 1.0 -1.1 0.2 0.6 -0.1 0.1 0.6 0.8 1.7 0.4 -0.1 0.7 -0.3 0.6 0.5 0.7 1.2 0.7 -0.5 0.7 0.8 1.4 1.6 0.3 -0.4 -1.2 -1.0 -1.2 -0.3
Wears glasses or contact lenses 1.5 1.7 9.4 -2.4 0.9 0.9 0.4 -0.3 -1.9 1.2 0.8 1.6 -1.4 1.6 0.2 -0.4 0.8 0.1 1.0 -0.7 1.3 0.3 1.6 -0.7 1.2 1.3 1.5 1.0 1.5 0.1 0.9 0.6 -0.9 0.2 -1.0 -1.5 -1.9 -3.1 -1.8 -2.2
Ever taken oral contraceptive pill 0.1 0.1 0.8 -0.2 -0.1 -0.1 -0.5 -0.7 -0.5 -0.3 -0.5 -0.1 -0.2 -0.2 -0.6 -0.4 -0.8 0.1 -0.1 -0.2 0.0 -0.8 0.1 0.1 -0.2 0.1 -0.1 -0.1 -0.1 -0.3 -0.0 -0.5 -0.3 -0.3 -0.2 -0.1 -0.0 -0.9 0.2 -0.0
Hearing aid user 0.1 0.1 0.9 -0.5 -0.3 0.1 0.9 -0.4 0.2 -0.0 -0.3 0.5 -0.1 -0.1 -0.2 -0.4 -0.1 1.0 -0.1 0.6 -0.1 -0.0 0.1 -0.9 0.3 -0.1 0.0 -0.0 0.2 -0.3 0.0 -0.1 -0.4 -0.0 -0.2 -0.3 -0.3 0.1 -0.3 -0.3
Mother’s age at death 0.2 0.3 1.2 0.6 -0.1 0.5 0.5 0.7 0.6 -0.1 1.1 -0.5 0.4 -0.4 0.4 0.3 0.1 -0.3 -0.3 -0.3 -0.4 -0.2 -0.5 -0.1 -0.1 -0.4 -0.4 -0.3 -0.3 0.9 -0.4 -0.1 -0.4 -0.3 0.5 0.8 0.6 0.9 1.1 0.8
Financial situation satisfaction 1.5 1.9 9.0 0.3 -0.9 -2.6 -2.0 -1.0 -1.4 -1.0 0.1 -1.7 1.0 -0.9 -1.0 -1.8 -1.5 -3.0 -1.5 -2.5 -0.8 -2.2 -1.0 -0.2 -0.7 -0.8 -1.0 -1.3 -1.5 -0.8 -0.7 -1.7 -1.0 -1.4 -0.9 0.2 1.5 -0.8 1.3 -0.2
Tinnitus: Yes, now most or all of the time 2.1 2.4 10.2 2.0 -1.4 0.0 1.9 1.0 1.4 -1.9 -1.5 -2.3 2.5 -1.6 -1.3 0.3 -0.6 -0.3 -1.5 -1.2 -1.9 -0.3 -2.0 -0.1 -1.6 -1.9 -1.9 -1.3 -2.2 -1.0 -1.7 -0.7 -1.0 -1.6 -0.3 0.6 3.2 2.4 1.5 0.7
Commuting to job workplace: Public transport 1.2 1.5 7.8 -2.0 1.0 1.8 -0.7 0.9 1.3 1.2 1.2 0.9 -1.8 0.6 0.3 0.5 0.9 1.4 1.0 1.7 0.8 0.9 0.9 0.3 0.9 0.8 1.0 1.0 1.1 0.6 0.7 1.0 0.6 1.1 -0.8 -2.1 -1.2 0.1 -2.8 -1.9
Eye problems/disorders: Glaucoma 3.4 4.1 9.8 0.5 -1.8 -1.8 -1.1 -0.9 -1.2 -2.4 -1.1 -3.1 2.1 -1.6 -3.1 -2.4 -2.4 -3.0 -2.3 -2.0 -1.8 -1.9 -1.9 -1.8 -2.2 -1.8 -1.9 -2.5 -2.2 -2.2 -1.9 -2.5 -2.4 -3.1 -2.2 -1.2 1.8 -0.0 0.2 -1.3
Medication: Blood pressure 0.1 0.3 1.4 -0.6 0.3 1.2 0.6 0.1 -0.1 0.1 0.4 -1.0 -0.3 0.5 -1.0 -0.6 -0.2 0.8 0.0 -0.2 0.3 0.6 0.3 -0.8 0.3 0.3 0.1 -0.0 0.1 -0.3 0.1 -0.3 -0.5 -0.3 -0.6 -0.6 -0.3 -1.1 -0.3 -0.6
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.0 -0.8 0.6 0.0 -0.4 0.2 0.0 0.6 1.0 -0.0 -0.6 0.8 -0.1 0.1 0.9 -0.5 0.6 0.1 0.6 0.1 0.5 0.1 0.6 0.6 0.6 0.7 0.5 0.2 0.5 0.7 0.8 0.7 0.1 -0.3 -0.6 -0.1 -0.8 -0.4
Supplements: Fish oil (including cod liver oil) 0.7 0.9 5.9 0.8 -0.2 -1.7 -2.4 -1.3 -0.8 0.5 0.4 1.7 0.1 -0.4 0.7 0.5 0.4 -0.0 0.5 1.3 0.2 -0.0 0.5 -1.0 0.5 0.2 0.5 0.8 0.4 0.3 0.6 0.7 2.0 1.2 1.6 1.4 -0.6 -0.3 0.5 1.4
High cholesterol (Self-reported) 1.0 1.7 5.7 -2.1 1.1 0.2 -0.9 -0.3 -0.9 1.3 0.9 1.1 -2.0 1.8 0.1 -0.3 1.1 0.4 1.3 0.3 1.5 -0.1 1.6 1.0 1.7 1.5 1.5 1.4 1.5 0.5 1.6 1.2 0.8 1.2 -0.7 -1.8 -1.8 -1.9 -2.4 -1.9
Medication: Bendroflumethiazide 0.9 1.3 6.1 -0.1 -0.8 -0.0 0.6 -0.3 0.2 -1.0 -0.3 -1.4 0.6 -1.0 -2.2 -1.5 -1.0 0.2 -1.1 -0.3 -0.9 -1.1 -0.9 -2.4 -1.3 -0.9 -1.0 -1.4 -0.8 -2.5 -1.1 -1.6 -1.6 -1.5 -1.5 -1.2 0.4 -0.2 -0.3 -1.1
Medication: Paracetamol 0.3 0.4 2.5 0.7 0.5 0.3 -0.0 1.6 1.4 0.6 0.5 0.8 0.6 -0.9 -0.4 0.8 0.6 -0.1 0.0 -0.5 -0.0 -0.6 -0.3 -1.0 -0.1 -0.0 -0.2 -0.2 -0.3 0.1 -0.2 0.5 0.4 -0.3 0.4 0.4 0.8 1.3 0.3 0.5
Medication: Lisinopril 1.2 1.6 5.6 0.2 -0.3 1.1 2.4 1.7 1.0 -1.1 0.3 -1.9 1.5 -0.7 -2.1 -0.4 -0.1 -0.8 -0.9 -1.8 -0.9 -0.2 -1.1 -0.8 -1.4 -1.0 -1.0 -1.2 -1.2 -1.9 -1.3 -0.6 -1.7 -2.0 -1.4 -1.2 1.7 1.0 -0.4 -1.3
Medication: Atorvastatin 0.4 0.5 4.6 0.4 0.7 0.6 0.2 1.7 2.2 0.4 0.9 -0.1 0.5 0.1 -0.0 1.0 0.7 0.3 0.5 0.4 0.2 0.3 0.1 0.4 -0.2 0.2 0.2 0.1 0.2 -0.7 0.3 0.6 0.3 -0.5 0.5 0.2 0.3 1.8 -0.3 0.3
Illnesses of father: High blood pressure 0.4 0.5 1.2 0.9 -0.7 -1.0 0.2 -0.8 -0.6 -0.6 -0.6 -0.9 0.6 -0.3 -1.0 -1.1 -0.6 -0.6 -0.5 -0.2 -0.6 -0.9 -0.7 0.1 -0.6 -0.6 -0.8 -0.3 -0.6 -0.3 -0.7 -0.4 0.5 0.2 0.7 1.1 0.4 0.3 1.0 0.9
Alcohol drinker status: Never 0.2 0.2 1.3 -0.3 0.3 0.2 0.1 1.0 0.7 0.3 -0.2 -0.2 0.3 0.6 -0.1 -0.4 0.2 -1.1 -0.0 -1.1 0.2 -0.5 0.3 0.3 0.3 0.1 0.3 -0.2 0.3 -0.2 0.3 -0.3 -0.5 -1.0 0.2 0.2 0.2 0.4 0.1 -0.1
Ever smoked 0.3 0.5 3.3 0.2 0.1 -0.6 -0.9 -0.3 0.1 0.3 0.2 1.8 0.2 -0.8 1.8 1.2 0.0 0.4 -0.1 0.5 0.1 0.6 0.0 -0.1 0.4 0.2 0.1 -0.2 -0.1 1.6 -0.1 -0.3 0.5 0.0 1.0 1.3 0.3 0.8 1.2 1.2
Basal metabolic rate 0.1 0.7 6.5 -0.2 -0.1 -1.3 -2.5 -0.5 -0.9 -0.2 -0.4 0.3 0.4 -0.3 0.2 -0.9 -0.4 -2.5 -0.3 -1.0 0.1 -1.3 -0.0 -0.9 -0.4 0.1 -0.1 -0.4 -0.3 -1.0 0.1 -0.6 -0.1 -0.6 -0.2 0.2 0.3 -0.8 0.5 -0.1
Leg fat percentage (left) 0.3 1.0 6.6 -1.1 0.8 1.7 0.7 1.9 0.8 -0.2 -0.0 -1.9 0.1 1.0 -0.4 -0.7 0.3 -2.6 -0.2 -2.5 0.4 -0.3 0.1 0.5 0.2 0.4 0.2 -0.3 -0.2 -0.3 0.1 -0.1 -1.0 -0.7 -1.6 -1.2 1.0 0.2 -0.3 -1.6
Arm fat-free mass (left) 0.1 0.7 8.2 -0.5 0.4 -1.2 -2.9 -0.5 -1.0 0.6 0.4 1.4 -0.3 0.0 1.3 -0.3 0.4 -2.0 0.4 -0.5 0.7 -0.4 0.6 -0.6 0.2 0.7 0.6 0.5 0.4 -0.3 0.7 0.2 0.8 0.4 0.2 0.3 -0.4 -1.3 0.1 0.0
Number of operations (self-reported) 0.7 1.1 3.9 -1.7 1.8 2.0 0.2 1.4 0.8 0.7 1.1 -0.3 -0.4 1.8 0.2 0.9 0.9 -0.0 1.1 -0.5 1.6 0.9 1.3 1.4 0.6 1.6 1.3 0.5 1.0 -0.8 1.3 0.8 -0.2 -0.8 0.0 -0.5 -0.5 -0.7 -0.8 -0.8
Average weekly beer plus cider intake 2.9 4.2 10.8 -1.3 2.9 1.9 0.6 2.4 1.9 2.7 1.3 3.3 -1.7 2.0 2.4 2.6 3.1 0.5 2.7 0.6 2.6 1.2 2.2 1.0 2.3 2.6 2.2 2.4 2.3 2.1 2.3 2.8 2.1 2.3 1.1 -0.0 -1.4 0.6 -1.6 -0.1
Irritability 2.0 3.3 6.8 -1.7 1.7 0.1 -2.6 -0.5 -0.7 2.5 1.5 2.6 -2.3 1.8 1.5 0.4 1.1 0.8 1.9 0.7 2.2 1.3 2.3 1.0 2.5 2.3 2.3 2.1 2.4 2.5 2.3 1.2 2.1 2.3 1.5 0.9 -2.5 -2.3 -0.2 0.6
Risk taking 0.6 0.9 7.4 0.8 -0.2 -1.0 -0.2 -0.5 -0.8 -0.2 -0.3 -0.6 0.7 -0.2 -1.1 -0.7 -0.9 -1.0 -0.8 -1.5 -0.1 -1.4 -0.2 -0.4 -0.5 -0.1 -0.2 -0.9 -0.3 -0.5 -0.3 -1.4 -0.2 -0.8 1.1 2.3 0.0 -0.3 2.7 1.8
Ever had prostate specific antigen (PSA) test 0.5 0.5 2.9 -0.6 -0.1 0.0 0.9 -0.5 -1.5 -0.1 -0.8 0.2 0.0 0.5 -0.2 -1.0 -0.8 -0.8 -0.6 -1.7 0.2 -1.0 0.3 -0.4 0.5 0.1 0.2 -0.5 0.1 0.4 0.0 -1.1 -1.1 -0.9 0.2 1.0 -0.2 -1.2 1.5 0.5
Fractured/broken bones in last 5 years 0.5 0.6 1.4 0.9 -1.0 -0.9 -0.3 -0.2 0.1 -1.2 -0.4 -0.8 1.0 -1.1 -0.5 -0.1 -0.6 -0.3 -0.9 0.2 -1.1 -0.6 -1.1 -0.2 -1.1 -1.1 -1.0 -1.0 -1.0 -1.0 -0.9 -0.5 -1.0 -1.0 -0.7 -0.4 0.8 0.3 0.2 -0.1
Age started oral contraceptive pill 0.6 0.8 3.9 -0.0 0.1 -0.0 -0.7 -1.4 -1.0 0.7 -0.2 0.7 -1.0 0.6 0.3 -0.8 0.8 0.9 0.8 2.0 0.6 0.9 0.9 -0.0 0.9 0.7 0.7 1.1 0.8 0.4 0.9 0.8 1.5 1.6 0.8 0.1 -1.6 -1.0 -1.0 0.3
Diastolic blood pressure, automated reading 0.9 2.8 7.7 0.7 -0.9 1.0 1.3 1.7 1.9 -1.9 -0.0 -2.8 2.1 -1.5 -1.6 -0.2 -1.0 -0.8 -1.7 -1.7 -1.7 0.4 -2.1 -0.4 -2.2 -1.7 -2.0 -2.0 -2.2 -2.1 -1.8 -1.4 -2.2 -2.4 -1.8 -0.8 2.8 1.5 0.7 -0.9
Ever depressed for a whole week 1.2 1.5 6.3 1.2 -1.6 -2.5 -0.6 -1.5 -0.9 -1.5 -0.2 -1.4 1.1 -1.5 -0.8 -1.3 -1.6 -1.4 -1.5 -0.3 -1.5 -1.9 -1.6 -0.5 -1.0 -1.4 -1.6 -1.3 -1.6 -0.7 -1.3 -1.2 -0.7 -0.7 -0.6 0.1 1.2 0.2 0.8 0.2
Unable to work because of sickness or disability 0.8 1.0 4.4 -1.4 1.0 -0.8 -2.1 0.2 0.3 0.9 1.2 0.4 -1.6 1.1 0.2 -0.0 0.8 -1.8 1.0 0.7 1.1 -0.4 0.9 1.2 1.2 1.1 1.0 1.0 1.0 1.2 1.2 0.8 1.3 1.3 0.2 -0.4 -1.3 -0.6 -0.8 -0.4
Commuting to job workplace: Cycle 0.5 0.6 2.6 -0.8 0.7 1.0 0.3 0.0 0.5 0.7 0.9 0.9 -0.7 0.6 0.8 0.9 0.7 1.6 0.9 1.4 0.7 1.3 0.7 -0.0 0.3 0.8 0.6 0.7 0.7 0.5 0.6 0.9 -0.0 0.3 -0.1 -0.7 -0.7 -0.4 -1.1 -0.5
Myopia 1.0 1.4 8.1 2.7 -0.7 -1.0 -1.7 -0.0 0.1 -0.3 -0.4 -0.8 1.4 -1.3 -0.5 -0.0 -0.8 0.5 -0.6 0.3 -0.9 -1.0 -0.9 -0.2 -1.1 -0.9 -0.8 -0.6 -0.8 -0.7 -0.6 -0.3 1.1 -0.3 2.0 2.5 0.6 1.3 2.2 2.8
Vascular/heart problems diagnosed by doctor 0.7 1.9 7.6 2.5 -1.4 -2.8 -2.2 -0.9 -0.3 -0.6 -1.1 1.1 1.7 -1.9 1.7 0.8 -0.4 -1.3 -0.8 0.1 -1.3 -1.4 -1.2 -0.2 -1.0 -1.4 -0.9 -0.6 -1.1 1.3 -0.9 -0.2 0.6 -0.3 1.4 2.1 1.2 1.8 2.1 2.3
Cholesterol lowering medication 0.7 1.0 2.1 -0.8 1.0 0.2 -0.8 -0.4 -0.8 1.2 1.0 0.8 -1.1 1.2 0.6 0.2 1.2 0.6 1.3 0.9 1.2 0.6 1.1 0.1 1.3 1.2 1.0 1.4 1.0 0.6 1.2 1.3 1.4 1.2 0.7 -0.3 -1.4 -1.1 -1.5 -0.4
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 6.2 0.6 -1.2 -0.6 0.6 -0.5 -0.7 -1.6 -0.7 -2.5 0.9 -0.6 -1.7 -1.6 -1.0 -1.1 -1.1 -0.7 -1.2 -1.1 -1.2 -0.6 -1.1 -1.2 -1.2 -1.0 -1.3 -2.1 -1.1 -0.7 -1.1 -0.8 -1.5 -1.2 1.0 -0.0 -0.5 -1.1
Pain experienced in last month 0.2 0.3 1.3 -0.7 0.0 1.1 0.8 0.4 0.6 0.1 0.1 0.7 -0.5 -0.1 -0.1 0.5 -0.1 0.4 0.0 0.6 -0.1 0.8 0.1 0.2 -0.1 -0.2 0.1 -0.2 0.4 0.9 -0.0 -0.2 -0.7 -0.2 -0.5 -1.0 -0.6 0.3 -1.1 -0.9
Supplements: Calcium 0.2 0.3 1.5 0.0 0.1 -0.2 -1.0 -0.7 -0.7 0.3 0.3 -0.1 -0.2 0.3 0.6 -0.5 -0.1 -0.5 0.3 -0.7 0.4 -0.5 0.5 -0.1 0.1 0.4 0.4 0.5 0.3 -0.4 0.5 0.1 0.1 0.1 0.7 1.2 -0.1 -0.3 1.2 1.0
Basal cell carcinoma (self-reported) 0.9 1.1 4.0 -1.9 1.1 0.5 -0.8 -0.1 -0.4 1.1 0.3 1.1 -1.7 1.1 0.5 -0.3 0.4 -0.6 1.1 0.8 1.3 0.2 1.2 0.1 0.9 1.3 1.1 1.0 1.1 0.7 1.0 0.7 0.4 0.9 -0.7 -1.6 -1.5 -1.2 -2.0 -1.5
Heart attack/myocardial infarction (self-reported) 2.4 3.1 7.3 -0.3 2.0 1.4 0.2 1.7 2.2 1.6 1.2 1.0 -0.9 2.0 1.2 2.4 2.1 1.8 2.1 1.9 1.8 1.8 1.8 2.3 1.9 1.7 1.9 2.0 1.8 1.2 2.3 2.5 2.7 1.9 2.4 1.2 -1.0 1.2 -0.6 1.5
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 4.0 2.0 -1.6 -0.7 1.5 -0.9 -0.9 -1.5 -1.3 -1.4 1.7 -1.4 0.0 -0.3 -1.2 -0.4 -1.5 -0.1 -1.6 -0.8 -1.5 -1.0 -1.6 -1.6 -1.5 -1.3 -1.5 -1.4 -1.7 -0.9 -1.5 -1.1 -0.1 0.9 1.2 0.4 1.5 1.0
Heart disease (siblings) 1.7 2.1 4.3 1.1 -2.1 -1.6 0.0 -1.6 -1.5 -1.8 -1.8 -1.1 1.2 -1.8 -1.3 -1.7 -1.8 -0.1 -1.9 -0.2 -1.9 -1.6 -1.7 -1.6 -1.5 -1.9 -1.8 -1.6 -1.7 -2.0 -1.8 -1.7 -1.5 -1.1 -1.2 -0.5 1.0 -0.2 0.4 -0.5
Alcohol drinker status: Previous 0.5 0.5 3.6 0.3 0.0 -0.6 -0.5 1.2 0.6 -0.5 0.4 -0.9 1.2 -0.1 0.4 0.9 0.7 -1.9 -0.1 -1.5 -0.3 -1.0 -0.3 0.2 -0.7 -0.4 -0.1 -0.2 -0.5 -0.6 -0.1 0.4 -0.4 -1.2 0.1 0.2 1.2 1.1 0.1 0.0
Pack years of smoking 0.1 0.2 1.2 0.2 0.4 -0.4 0.1 1.0 0.2 0.4 -0.1 0.4 0.4 0.0 0.3 0.4 0.6 -0.7 0.3 -0.8 0.2 -1.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.5 0.3 0.0 -0.0 -0.2 0.3 0.2 -0.5 -0.3
Impedance of whole body 0.1 0.7 5.0 0.4 -0.3 1.3 2.2 0.6 1.4 -0.6 0.5 -1.8 -0.1 0.1 -1.0 0.4 -0.1 1.7 -0.2 1.3 -0.6 1.1 -0.7 1.0 -0.1 -0.6 -0.7 -0.3 -0.3 0.2 -0.6 -0.0 -0.3 0.2 -0.5 -0.6 0.2 1.2 -0.4 -0.3
Leg fat mass (left) 0.2 0.8 8.1 -1.1 0.6 0.9 -0.2 1.4 0.4 -0.3 -0.2 -1.4 0.1 0.7 -0.3 -0.8 0.2 -2.8 -0.2 -2.0 0.4 -0.6 0.0 0.2 0.0 0.3 0.1 -0.3 -0.2 -0.6 0.1 -0.2 -0.8 -0.6 -1.3 -1.1 0.8 0.0 -0.3 -1.4
Arm predicted mass (left) 0.1 0.7 8.2 0.2 -0.1 -1.7 -2.9 -0.7 -1.0 0.1 -0.1 0.9 0.4 -0.5 0.9 -0.5 -0.1 -2.2 -0.1 -0.7 0.1 -1.1 0.1 -0.9 -0.3 0.2 0.1 -0.1 -0.1 -0.6 0.2 -0.2 0.5 -0.1 0.4 0.7 0.1 -0.8 0.7 0.4