Hub : Genes

CCDC13-AS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2730 0.0470 5.6e-12 0.106 NA 0.228 NA 0.237 5.8e-09 NA 1.6e-18 NA 2.8e-19
2 GTEx Adipose Visceral Omentum 0.1160 0.0510 7.0e-03 0.103 NA 0.081 NA 0.086 5.4e-06 NA 5.3e-05 NA 3.1e-05
3 GTEx Artery Aorta 0.1630 0.0510 1.5e-04 0.118 NA 0.083 NA 0.093 4.7e-07 NA 2.5e-05 NA 8.2e-06
4 GTEx Artery Tibial 0.1658 0.0431 9.0e-07 0.114 NA 0.125 NA 0.123 3.2e-09 NA 4.9e-10 NA 7.0e-10
5 GTEx Cells Transformed fibroblasts 0.3450 0.0560 9.9e-14 0.218 NA 0.239 NA 0.223 2.7e-16 NA 6.6e-18 NA 1.1e-16
6 GTEx Colon Transverse 0.1060 0.0470 7.3e-03 0.008 NA 0.049 NA 0.052 1.2e-01 NA 2.2e-03 NA 1.8e-03
7 GTEx Esophagus Mucosa 0.0800 0.0330 7.2e-03 0.043 NA 0.011 NA 0.027 7.1e-04 NA 6.0e-02 NA 6.5e-03
8 GTEx Esophagus Muscularis 0.1960 0.0530 1.8e-05 0.118 NA 0.106 NA 0.100 1.2e-07 NA 5.7e-07 NA 1.2e-06
9 GTEx Lung 0.0939 0.0370 2.7e-03 0.000 NA 0.022 NA 0.003 3.0e-01 NA 7.5e-03 NA 1.7e-01
10 GTEx Pituitary 0.4770 0.1170 8.3e-04 0.217 NA 0.237 NA 0.109 3.6e-06 NA 1.2e-06 NA 1.1e-03
11 GTEx Spleen 0.2860 0.0940 1.1e-03 0.133 NA 0.068 NA 0.235 2.8e-04 NA 7.9e-03 NA 1.0e-06
12 GTEx Thyroid 0.3510 0.0520 1.7e-16 0.277 NA 0.339 NA 0.346 2.2e-21 NA 9.5e-27 NA 2.2e-27
13 GTEx Whole Blood 0.0950 0.0320 7.3e-04 0.074 NA 0.070 NA 0.074 2.4e-07 NA 4.9e-07 NA 2.2e-07
14 ROSMAP Brain Pre-frontal Cortex 0.2983 0.0415 0.0e+00 0.292 0.263 0.305 0.3 0.304 6.7e-38 1.1e-33 7.2e-40 4.1e-39 1.4e-39

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.6 2.5 4.3 1.4 2.0 0.3 0.8 1.9 1.6 1.7 1.8 1.5 1.8 0.6 1.6 2.1 -2.0
Bipolar Disorder or Schizophrenia 0.2 0.6 1.8 0.7 0.7 0.1 0.5 0.5 1.2 0.7 0.7 0.3 1.3 0.4 0.7 1.0 -0.8
Depressed Affect (Nagel 2018) 0.2 0.3 1.5 -0.2 0.3 0.8 -0.2 -0.6 0.7 0.2 0.0 -1.2 -0.8 0.9 0.3 0.3 -0.1
Depression (Nagel 2018) 1.8 2.7 5.5 -1.5 -2.2 0.6 -0.6 -2.3 -0.8 -2.3 -2.1 -1.5 -0.9 -0.3 -1.7 -1.9 2.2
Intelligence (Savage-Jansen 2018) 0.1 0.2 1.1 -0.0 -0.5 1.1 -0.1 -0.4 0.2 0.2 -0.2 -0.3 -0.8 0.3 0.2 -0.8 0.6
Neuroticism (Nagel 2018) 0.2 0.6 4.7 -0.4 -0.1 0.6 -0.6 -0.5 -0.0 -0.0 -0.3 -2.2 -1.3 0.5 0.1 0.2 0.2
Schizophrenia (2018) 0.1 0.3 0.9 -0.2 -0.7 -0.1 -0.0 -0.9 0.3 -0.5 -0.6 -0.9 0.2 0.1 -0.4 -0.4 0.6
Schizophrenia vs Biploar Disorder 0.4 0.5 1.4 -0.6 -1.0 0.1 -0.1 -0.7 -0.3 -0.7 -0.9 -1.1 -0.7 -0.3 -0.7 -0.4 1.2
Worry (Nagel 2018) 0.2 0.5 4.2 -0.5 -0.1 -0.5 -0.7 -0.4 -0.7 -0.3 -0.4 -2.0 -0.9 -0.3 -0.2 0.3 0.3
Alzheimer’s Disease (in mother) 1.0 1.1 2.9 -1.5 -1.0 -0.4 -1.7 -0.7 -0.6 -0.9 -1.3 -1.4 -0.8 -0.6 -0.8 -0.9 1.2
Alzheimer’s Disease (in father) 0.1 0.1 0.5 -0.4 0.1 0.1 -0.4 0.1 0.7 0.2 -0.1 -0.4 0.3 0.5 0.2 0.4 0.0
Alzheimer’s Disease (including proxy) 0.1 0.2 0.8 -0.2 0.3 0.5 -0.5 0.3 0.9 0.3 0.1 -0.3 0.5 0.6 0.6 0.4 -0.2
Crohns Disease (2017) 0.6 1.3 2.3 1.5 1.2 0.2 1.2 0.7 0.4 1.2 1.4 1.1 1.5 0.7 1.2 1.1 -1.4
Irritable Bowel Disease (IBD) 0.1 0.3 0.8 0.6 0.3 -0.8 0.1 -0.2 -0.7 0.4 0.4 0.9 0.7 -0.5 0.3 0.2 -0.5
Ulcerative Colitis (UC) 0.4 0.7 2.1 -0.4 -0.7 -1.4 -0.7 -0.9 -1.4 -0.6 -0.6 0.1 -0.4 -1.3 -0.7 -0.9 0.6
Major Depression (MDD) 0.4 0.5 1.3 0.2 0.9 -0.1 -0.4 0.7 0.8 1.1 0.7 -0.1 0.6 0.6 0.8 1.0 -0.8
Reaction Time 1.8 3.5 5.2 -1.7 -1.8 -2.0 -1.7 -1.4 -2.3 -1.8 -2.0 -1.9 -1.7 -2.1 -1.8 -2.1 1.8
Verbal and Numeric Reasoning (VNR) 0.5 1.2 2.7 1.0 1.0 1.7 0.9 0.5 1.6 1.4 1.1 0.8 0.1 1.4 1.3 0.7 -0.8
Breast Cancer 1.3 3.2 5.8 1.9 1.7 1.7 1.8 2.4 1.7 1.8 1.9 1.5 1.7 1.7 2.0 1.3 -1.9
Ovarian Cancer 0.3 0.4 1.3 -0.5 -1.0 -0.2 -0.2 -0.5 0.0 -0.8 -0.9 -0.1 -0.5 -0.2 -0.7 -0.7 1.1
Prostate Cancer 0.2 0.3 1.8 0.4 0.1 1.1 0.5 0.3 0.2 0.1 0.2 0.5 0.4 1.4 0.7 0.0 -0.1
Age at First Birth 1.2 1.7 3.4 1.0 1.8 0.2 0.1 1.6 -0.3 1.8 1.7 1.6 0.4 0.5 1.4 1.8 -1.8
Bipolar Disorder (2011) 0.3 0.3 1.4 -0.5 0.2 -0.8 -0.9 0.4 -0.2 0.5 -0.1 -1.2 -0.4 -0.4 0.1 0.5 0.0
Body Mass Index (BMI) (2010) 1.3 1.8 3.0 0.8 1.2 1.6 1.2 1.5 1.7 1.3 1.1 0.4 1.6 1.6 1.3 1.7 -1.1
Coronary Artery Disease (CAD) 1.1 1.3 3.1 -1.2 -0.9 -0.6 -1.7 -1.4 -0.1 -0.8 -1.0 -1.5 -1.8 -0.3 -0.9 -1.1 1.1
Crohns Disease (2012) 0.1 0.1 0.2 0.4 -0.2 -0.2 0.3 0.3 0.5 0.1 -0.0 -0.0 0.5 0.4 0.2 -0.4 -0.0
Mean Putamen Volume 1.0 1.2 3.1 1.0 0.7 1.5 1.0 0.8 1.5 0.9 0.9 0.6 1.0 1.8 1.0 1.0 -0.8
Fasting Glucose 2.7 3.3 5.4 -2.3 -1.9 0.1 -1.9 -1.9 -1.6 -1.8 -2.1 -2.0 -2.0 -1.0 -1.9 -1.2 2.2
HbA1C 0.9 0.9 1.8 -0.9 -1.2 0.6 -1.1 -1.0 -1.3 -1.2 -1.1 -0.8 -0.9 -0.2 -1.0 -0.6 1.1
HDL Cholesterol 0.1 0.1 1.1 0.2 -0.2 -0.0 0.2 -0.2 -0.3 -0.2 -0.0 1.0 -0.5 -0.4 -0.2 -0.2 0.0
LDL Cholesterol 0.3 0.5 2.2 0.6 0.5 1.0 0.6 0.4 1.5 0.7 0.6 -0.3 0.1 0.8 0.7 0.7 -0.5
Lupus 0.2 0.3 0.7 0.6 0.3 0.6 0.8 0.5 0.4 0.3 0.4 0.7 0.8 0.8 0.3 0.1 -0.5
Neuroticism (2016) 0.3 0.4 1.6 -0.3 -0.6 0.2 -0.1 -0.6 -0.3 -0.6 -0.5 -1.3 -0.8 0.2 -0.4 -1.0 0.5
Primary Biliary Cirrhosis 0.1 0.1 0.3 -0.3 -0.2 -0.2 -0.5 0.3 -0.2 -0.1 -0.3 -0.5 0.0 -0.1 -0.3 -0.2 0.3
Rheumatoid Arthritis 0.1 0.1 0.7 -0.2 -0.2 -0.5 0.1 -0.8 -0.3 -0.3 -0.1 0.3 0.0 -0.0 -0.5 0.3 0.2
Schizophrenia (2014) 0.1 0.1 0.7 -0.1 -0.1 0.1 -0.1 -0.3 0.5 0.2 -0.2 -0.9 -0.1 0.5 0.1 0.4 0.2
Triglycerides 0.5 0.9 1.8 -0.9 -1.2 1.1 -0.5 -0.8 0.0 -1.3 -1.2 -1.3 -0.7 -0.1 -0.6 -0.7 1.3
Type 2 Diabetes (T2D) (2012) 0.4 0.5 1.0 0.6 0.9 0.7 0.6 0.5 0.3 0.9 0.8 0.3 0.3 1.0 0.7 0.7 -0.7
Ulcerative Colitis 0.1 0.2 0.9 -0.2 -0.7 0.0 -0.1 -1.0 -0.2 -0.4 -0.6 0.2 -0.2 -0.2 -0.1 -0.3 0.7
Blood Eosinophil Count 1.7 13.5 31.0 -2.1 -5.4 3.3 0.8 -5.3 -0.8 -5.6 -4.3 -1.6 0.2 -0.3 -3.5 -5.4 4.6
Blood Platelet Count 0.3 2.9 5.9 -2.0 -1.3 -2.4 -2.0 -1.5 -1.5 -1.0 -1.7 -2.3 -1.6 -1.6 -1.8 -1.1 1.6
Blood Red Count 0.1 0.6 4.2 -0.6 0.3 1.1 -0.4 0.7 -0.1 0.4 -0.2 -2.0 -0.8 0.4 0.5 0.1 0.2
Blood White Count 0.8 5.8 21.6 -0.1 -2.9 4.7 3.1 -2.7 1.7 -3.4 -1.8 0.5 0.5 1.7 -1.4 -2.6 2.0
Heel T-Score 0.6 4.6 9.5 -2.0 -2.4 -0.9 -1.2 -2.3 -1.2 -2.3 -2.4 -2.8 -1.7 -1.5 -2.2 -3.1 2.6
BMI 0.2 0.9 7.5 -0.6 0.0 0.9 0.8 0.9 0.9 0.1 -0.5 -2.7 0.9 0.3 0.1 -0.4 0.7
Height 0.1 2.6 24.3 0.4 0.2 -2.6 0.1 -0.6 -4.9 -0.0 0.5 1.2 -0.3 -1.4 -0.6 0.1 -0.6
Waist Hip Ratio (WHR) 3.5 15.5 21.3 -4.0 -4.1 -2.9 -3.6 -4.2 -3.7 -4.3 -4.2 -4.6 -2.8 -3.5 -4.2 -4.5 4.1
Systolic Blood Pressure 0.5 2.4 4.5 -1.6 -1.2 -1.9 -1.9 -1.9 -1.6 -1.1 -1.4 -1.4 -2.1 -1.4 -1.6 -0.4 1.4
Smoking Status 0.5 1.3 2.8 1.0 1.2 1.0 1.1 1.4 1.1 1.1 1.1 0.8 0.7 1.7 1.2 1.1 -1.1
Allergy or Eczema 0.3 0.8 4.1 1.1 0.4 1.0 1.0 0.2 0.5 0.4 0.6 -0.5 2.0 1.1 0.8 -0.1 -0.6
Cardiovascular Disease 1.2 3.8 11.8 -2.6 -1.5 -0.9 -2.0 -1.2 -0.4 -1.4 -2.1 -3.4 -3.0 -0.5 -1.8 -1.8 2.1
Hypothyroidism (self reported) 0.1 0.3 1.1 -0.0 0.9 -0.9 -0.3 0.4 -0.2 1.1 0.5 -0.5 -0.1 -0.1 0.5 0.5 -0.6
Respiratory disease 0.3 0.6 1.3 0.5 1.0 -0.2 -0.1 0.9 0.6 1.2 0.8 -0.3 0.7 1.1 0.8 1.1 -0.9
Type 2 Diabetes (T2D) (2018) 4.7 8.7 11.6 -3.3 -2.8 -3.1 -3.4 -2.9 -2.7 -2.5 -3.2 -3.1 -2.3 -3.1 -3.0 -2.8 3.2
Lung FEV1/FVC ratio 0.2 1.1 2.6 1.1 1.2 -0.3 1.2 1.2 1.0 1.2 1.1 0.9 1.6 0.4 0.9 0.7 -1.1
Lung FVC 1.9 9.7 19.0 3.3 3.0 2.8 3.1 2.7 2.3 2.8 3.3 4.4 2.9 3.1 3.1 3.2 -3.2
Neuroticism 0.9 2.1 5.6 -1.5 -1.1 -0.6 -1.7 -1.7 -1.3 -1.3 -1.4 -2.4 -2.2 -0.6 -1.3 -0.9 1.2
Chronotype (morning person) 0.1 0.2 0.8 -0.4 -0.1 -0.1 -0.0 -0.6 -0.1 -0.3 -0.1 -0.6 -0.9 -0.4 -0.4 -0.8 0.0
Hair Pigment 0.7 18.8 32.8 5.4 3.7 3.0 5.2 4.2 4.3 3.4 4.5 5.7 4.9 3.1 4.0 3.6 -4.5
Tanning 0.0 0.3 1.5 -0.1 0.5 0.6 -0.2 0.2 0.0 0.5 0.5 0.3 -1.2 0.1 0.4 0.9 -0.3
Hand grip strength (left) 1.1 2.8 4.5 1.9 1.3 1.7 2.1 1.4 0.9 1.3 1.6 1.8 1.9 2.0 1.5 1.7 -1.6
Number of treatments/medications taken 1.6 2.8 5.5 -2.3 -1.6 -0.8 -2.3 -0.9 -0.4 -1.4 -2.0 -2.2 -2.1 -0.4 -1.6 -1.8 1.9
Average weekly spirits intake 0.2 0.3 1.6 -0.6 -0.3 0.8 -0.1 -0.2 0.5 -0.2 -0.5 -1.3 -0.3 0.5 0.1 -0.6 0.4
Sensitivity / hurt feelings 0.4 0.6 2.0 0.7 0.6 1.4 0.8 0.7 1.1 0.7 0.6 -0.5 -0.4 1.0 0.9 0.4 -0.7
Frequency of depressed mood in last 2 weeks 2.8 4.0 6.8 -2.1 -2.4 -0.6 -1.5 -2.6 -1.4 -2.5 -2.5 -1.7 -1.2 -1.1 -2.2 -2.3 2.4
Hearing difficulty/problems: Yes 0.2 0.3 1.6 -0.2 0.3 -1.0 -0.7 0.1 -0.6 0.1 -0.0 -1.3 0.7 -0.5 0.1 -0.1 -0.2
Relative age of first facial hair 0.9 1.8 4.7 1.3 0.9 2.2 1.4 0.5 2.1 0.7 1.1 1.2 0.9 1.8 1.4 0.8 -1.0
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 3.8 -1.4 -1.2 -0.3 -0.9 -0.8 -1.2 -1.2 -1.3 -0.9 -1.9 -0.8 -1.2 -0.9 1.4
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.4 -0.4 -0.8 0.6 -0.0 -0.8 0.2 -0.6 -0.8 -1.2 0.1 0.0 -0.4 -0.8 1.0
Ever had hysterectomy (womb removed) 4.7 5.3 7.5 2.2 2.4 2.0 2.4 2.4 2.7 2.2 2.6 1.7 1.6 2.7 2.4 2.1 -2.5
Systolic blood pressure, automated reading 0.1 0.4 1.8 0.4 0.7 -1.0 -0.2 0.2 -0.4 0.7 0.5 -0.1 0.3 -0.5 0.3 1.3 -0.5
Eye problems/disorders: Diabetes related eye disease 3.2 3.5 4.7 -2.0 -1.9 -1.7 -1.8 -2.0 -1.9 -2.1 -2.0 -1.3 -1.9 -1.8 -2.2 -1.6 1.9
Angina 1.7 2.2 6.0 -1.6 -1.8 0.2 -0.6 -1.4 -0.4 -1.7 -1.9 -2.4 -1.1 -0.7 -1.3 -1.9 1.9
Medication for hormone replacement therapy 0.6 0.7 1.7 -1.0 -0.7 -0.8 -1.2 -0.4 -0.2 -0.4 -0.8 -1.3 -0.4 -0.5 -0.9 -0.9 0.9
Vitamin and mineral supplements 1.1 1.5 3.8 -0.9 -1.2 -0.8 -0.8 -1.9 -1.2 -1.3 -1.2 -1.4 -1.2 -1.3 -1.1 -0.7 1.4
Supplements: Zinc 5.6 6.1 10.1 1.7 3.0 1.7 1.8 2.4 2.2 3.2 2.9 2.4 -0.0 3.0 2.8 2.9 -2.6
Medication: Co-codamol 0.9 1.1 2.2 0.9 0.8 1.4 1.4 1.0 1.5 0.9 0.9 0.7 0.3 1.2 1.2 0.7 -0.7
Medication: Metformin 0.7 1.0 2.2 -1.3 -0.8 -1.4 -1.4 -0.7 -1.1 -0.7 -1.1 -0.5 -0.9 -1.5 -0.8 -0.7 1.1
Diabetes (father) 0.4 0.5 1.5 -0.7 -0.3 -1.2 -1.0 -0.6 -1.0 -0.3 -0.7 -0.7 0.2 -0.8 -0.3 -0.4 0.6
Diabetes (mother) 0.8 1.1 3.7 -0.6 -0.4 -1.6 -0.7 -0.6 -1.9 -0.1 -0.7 -1.9 -1.0 -1.2 -0.5 -0.4 0.7
Severe depression (siblings) 0.2 0.2 0.9 -0.3 0.2 -0.3 -0.7 -0.0 0.3 0.0 -0.1 -0.8 -0.9 0.3 -0.2 0.4 -0.0
Pack years adult smoking proportion 1.1 1.6 4.2 -1.0 -1.7 0.4 -0.1 -1.2 -0.3 -2.0 -1.6 -1.5 -0.3 -0.6 -1.3 -1.7 1.6
Impedance of leg (right) 0.7 3.4 12.6 2.7 1.5 -0.7 1.4 1.0 1.0 1.4 2.2 3.5 1.9 0.3 1.1 2.0 -2.4
Leg fat-free mass (left) 0.3 1.5 4.5 -1.4 -0.8 -0.3 -0.1 -0.7 -1.9 -0.9 -1.3 -2.1 -1.3 -0.6 -1.0 -1.3 1.3
Trunk fat percentage 0.8 3.1 8.8 2.2 1.8 0.9 3.0 1.8 0.7 1.4 2.0 1.0 2.2 0.6 1.5 1.7 -2.1
Hand grip strength (right) 1.0 2.8 5.7 1.8 1.2 1.9 2.1 1.7 1.7 1.2 1.4 1.5 1.8 2.4 1.3 1.2 -1.5
Townsend deprivation index at recruitment 0.6 0.9 2.7 -1.1 -0.7 0.1 -0.9 -0.7 -1.1 -0.6 -0.7 -1.3 -1.6 -0.3 -0.8 -0.9 0.9
Current tobacco smoking 0.3 0.5 2.2 0.3 -0.8 0.1 0.8 -0.5 0.4 -0.8 -0.3 1.0 1.5 -0.2 -0.5 -1.1 0.4
Average weekly fortified wine intake 0.1 0.2 0.9 -0.1 -0.4 0.4 0.1 0.3 0.5 -0.1 -0.2 1.0 -0.6 0.2 0.0 -0.3 0.3
Maternal smoking around birth 0.3 0.4 1.7 0.6 0.5 0.1 1.0 0.8 1.3 0.6 0.5 0.3 0.6 0.5 0.4 0.3 -0.4
Fed-up feelings 0.1 0.2 1.3 -0.4 0.2 0.2 -0.4 -0.8 -0.0 0.1 0.0 -0.2 -1.2 0.5 -0.0 0.3 -0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.4 -0.2 -0.8 1.5 0.2 -0.5 0.6 -1.0 -0.7 0.2 0.7 1.2 -0.2 -0.6 0.7
Relative age voice broke 4.0 6.1 8.0 2.5 2.6 2.4 2.3 2.4 2.4 2.5 2.7 1.4 2.0 2.8 2.8 2.5 -2.8
Taking other prescription medications 0.7 1.1 2.4 -1.1 -1.4 0.1 -0.6 -0.9 0.2 -1.3 -1.4 -1.4 -0.4 -0.3 -1.0 -1.5 1.4
Age when periods started (menarche) 0.5 1.2 2.8 1.3 0.5 1.5 1.3 0.6 1.7 0.5 0.9 0.6 1.5 1.3 0.8 0.7 -0.8
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 5.6 1.8 1.6 1.0 1.7 1.4 1.8 1.5 1.6 0.4 2.4 1.2 1.7 1.3 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.8 -0.3 -0.6 1.0 0.4 -0.4 0.4 -0.5 -0.5 -0.1 -0.3 1.0 -0.2 -1.4 0.8
Tinnitus: Yes, but not now, but have in the past 1.2 1.2 2.7 -0.9 -1.7 0.1 -0.5 -1.2 -0.6 -1.5 -1.5 -0.9 -0.0 -0.8 -1.1 -1.4 1.5
Qualifications: CSEs or equivalent 2.0 2.6 4.6 1.8 2.0 0.1 1.4 1.6 1.3 2.1 2.1 1.1 1.5 1.0 1.6 1.8 -2.1
Serious illness, injury or assault to yourself 1.7 2.1 5.2 -1.8 -1.5 0.1 -0.9 -1.2 0.1 -1.5 -1.6 -2.1 -2.3 -0.4 -1.3 -1.6 1.7
High blood pressure 0.6 1.6 5.2 -1.6 -1.0 -0.8 -1.1 -0.8 -0.1 -1.0 -1.3 -2.3 -1.8 -0.5 -1.2 -1.4 1.3
Hayfever, allergic rhinitis or eczema 0.1 0.2 1.3 0.5 0.3 0.3 0.1 0.3 0.2 0.3 0.3 -0.2 1.2 0.6 0.5 0.0 -0.4
Multivitamins +/- minerals 1.3 1.7 4.5 1.1 1.1 0.9 1.0 1.7 1.1 1.2 1.3 2.1 1.3 1.5 1.0 0.7 -1.5
Stomach or abdominal pain in last month 4.4 5.5 9.2 -2.4 -2.9 -1.3 -2.2 -2.8 -1.3 -3.0 -2.8 -0.9 -1.6 -1.5 -2.8 -3.0 2.7
Supplements: Glucosamine 0.1 0.2 0.7 0.2 0.2 -0.5 0.3 0.7 0.9 0.2 0.4 0.0 0.5 0.0 -0.1 0.1 -0.3
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 1.6 -1.2 -0.3 -1.2 -1.2 -1.0 -0.8 -0.4 -0.5 -0.3 -1.1 -0.6 -0.9 -0.4 0.5
Medication: Atenolol 1.5 1.9 4.5 -1.7 -1.7 0.2 -0.6 -1.0 -0.4 -1.6 -1.8 -2.1 -1.5 -0.2 -1.4 -1.5 1.8
Medication: Levothyroxine sodium 0.2 0.3 1.3 -0.5 0.2 -1.1 -1.0 -0.0 -0.2 0.5 -0.1 -0.8 -0.4 -0.4 -0.1 0.2 0.1
Sitting height 0.2 1.6 8.6 0.7 1.1 -2.7 0.1 -0.0 -2.9 1.1 0.9 0.3 0.3 -0.7 0.1 0.7 -1.1
Chronic bronchitis/emphysema (father) 0.1 0.1 0.3 -0.3 0.2 -0.4 -0.2 0.3 0.2 0.2 0.0 -0.6 0.1 -0.0 0.1 0.3 -0.1
High blood pressure (mother) 1.1 1.6 2.8 -0.9 -1.6 -1.3 -0.5 -1.1 -1.0 -1.7 -1.4 0.2 -0.9 -1.4 -1.5 -1.6 1.4
Body mass index (BMI) 0.3 1.4 5.0 0.2 0.8 2.2 1.6 1.3 1.6 0.5 0.3 -1.8 0.4 1.3 0.9 0.5 -0.3
Impedance of leg (left) 0.7 3.3 9.5 2.6 1.6 -0.6 1.2 0.9 1.1 1.5 2.2 3.1 2.0 0.5 1.2 2.2 -2.4
Leg predicted mass (left) 0.3 1.6 4.8 -1.4 -0.9 -0.4 -0.1 -0.7 -2.0 -1.0 -1.4 -2.2 -1.4 -0.7 -1.0 -1.4 1.4
Trunk fat mass 0.3 1.3 5.1 1.3 1.2 0.7 2.3 1.3 0.1 0.9 1.2 0.1 1.3 0.3 0.9 1.1 -1.2
Waist circumference 0.2 0.6 4.9 -0.7 -0.3 0.8 0.6 0.0 0.0 -0.6 -0.7 -2.2 -0.1 -0.0 -0.3 -0.5 0.7
Number of incorrect matches in round 0.2 0.3 0.6 0.3 0.7 -0.7 -0.2 0.8 0.2 0.7 0.7 0.2 -0.1 -0.1 0.4 0.6 -0.7
Past tobacco smoking 2.1 3.9 7.9 -1.6 -2.3 -1.4 -1.2 -2.8 -2.0 -2.4 -2.0 -0.3 -1.4 -2.3 -2.3 -2.0 2.1
Alcohol usually taken with meals 0.5 0.8 1.6 1.1 0.8 -1.3 0.3 1.0 -0.2 0.9 1.0 1.0 0.7 -1.0 0.4 0.8 -1.1
Nervous feelings 0.3 0.5 1.2 0.5 0.8 1.1 0.2 0.4 0.5 0.9 0.7 0.0 -0.1 1.1 0.9 1.1 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.3 0.1 -0.1 1.0 0.6 -0.8 0.0 -0.3 -0.1 0.2 0.6 1.2 0.1 -0.2 0.2
Hearing difficulty/problems with background noise 1.0 1.5 3.7 0.8 1.9 0.6 0.2 1.0 1.5 1.5 1.4 -0.3 0.4 1.0 1.5 1.8 -1.6
Hair/balding pattern: Pattern 2 1.2 1.5 7.5 -1.0 -0.0 -2.7 -1.9 -0.4 -2.0 0.1 -0.5 -0.7 -1.0 -1.6 -0.7 0.1 0.3
Had menopause 0.2 0.3 2.5 -0.1 -0.5 0.5 0.0 -0.1 -0.0 -0.4 -0.4 -1.6 0.2 -0.4 -0.1 -0.4 0.5
Had other major operations 0.3 0.3 1.0 -0.2 -0.2 1.0 0.5 0.5 0.7 -0.6 -0.4 -0.7 0.8 0.6 0.0 -0.8 0.3
Forced vital capacity (FVC) 1.3 5.2 10.3 2.9 2.2 0.8 2.5 2.3 0.5 2.2 2.6 3.2 2.4 1.6 2.1 2.2 -2.6
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.5 -0.2 -0.5 1.2 0.6 -0.5 0.4 -0.5 -0.5 -0.2 -0.9 1.0 -0.0 -1.0 0.9
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 0.6 0.4 0.4 -0.4 0.1 0.4 -0.5 0.2 0.4 -0.2 0.4 -0.8 -0.0 0.2 -0.6
Qualifications: None of the above 0.2 0.5 1.4 0.4 0.6 1.1 0.8 0.6 0.6 0.4 0.6 0.9 0.2 0.9 0.6 1.2 -0.7
Financial difficulties in last 2 years 0.5 0.7 2.9 -0.1 -0.8 1.7 0.8 -1.2 0.5 -0.9 -0.6 -0.4 0.0 1.4 -0.3 -0.5 0.9
Mouth/teeth dental problems 0.2 0.3 1.8 0.2 0.4 -0.3 -0.4 0.5 0.1 0.7 0.4 1.3 0.7 -0.0 0.3 0.1 -0.2
Heart attack 0.7 0.9 2.4 -1.0 -1.1 0.1 -0.5 -0.6 -0.1 -1.2 -1.2 -1.5 -0.2 -0.4 -0.9 -1.3 1.1
Allergy 0.1 0.2 0.7 -0.1 -0.3 -0.4 0.1 -0.4 -0.4 -0.3 -0.2 0.8 -0.7 -0.8 -0.4 -0.0 0.3
Pain all over the body in last month 0.3 0.3 1.0 0.4 0.7 0.4 0.6 0.4 1.0 0.5 0.6 0.3 0.0 0.5 0.7 0.6 -0.5
Diabetes (self-reported) 2.3 3.5 7.4 -2.0 -1.6 -2.7 -2.3 -1.9 -2.1 -1.3 -1.8 -0.8 -1.7 -2.5 -1.8 -1.2 1.7
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.1 -0.1 -0.9 0.2 -0.0 -0.7 -0.1 -0.8 -0.6 -0.1 0.8 0.2 -0.6 -1.1 0.6
Medication: Ramipril 0.3 0.3 1.4 -0.8 -0.1 -0.9 -0.8 -0.5 0.2 -0.2 -0.5 -0.2 -1.2 0.1 -0.5 0.5 0.3
Medication: Simvastatin 1.2 1.8 4.1 -2.0 -0.8 -1.3 -2.0 -1.0 -1.7 -0.7 -1.3 -1.3 -1.9 -0.5 -1.1 -0.5 1.2
Fluid intelligence score 0.1 0.3 0.8 0.7 0.2 0.9 0.8 -0.4 0.2 0.3 0.5 0.7 -0.1 0.3 0.5 -0.1 -0.4
Illnesses of siblings 0.6 0.8 6.5 0.5 -0.8 0.8 0.9 -0.5 0.1 -1.0 -0.0 2.6 -0.3 0.0 -0.4 -1.0 0.1
Neuroticism score 0.2 0.5 2.8 -0.4 -0.2 0.1 -0.7 -0.8 -0.2 -0.3 -0.4 -1.4 -1.7 -0.1 -0.3 -0.3 0.3
Weight 0.1 0.5 2.2 0.2 0.6 0.9 1.5 0.9 -0.1 0.4 0.3 -1.4 0.3 0.6 0.5 0.2 -0.3
Impedance of arm (right) 0.7 3.1 12.7 2.2 1.2 -2.3 0.6 0.5 -1.9 1.0 1.9 3.6 1.8 -1.1 0.5 1.4 -2.1
Arm fat percentage (right) 0.4 1.7 4.5 1.2 1.4 1.4 2.1 1.6 1.0 1.1 1.2 -0.0 1.3 0.8 1.3 1.2 -1.3
Trunk fat-free mass 0.4 2.4 6.7 -2.1 -1.2 -0.1 -0.9 -1.1 -1.4 -1.2 -1.8 -2.6 -2.3 -0.2 -1.1 -1.6 1.9
Hip circumference 0.4 1.6 4.3 1.1 1.4 1.3 2.1 1.6 1.0 1.1 1.1 0.1 1.1 1.1 1.2 1.2 -1.1
Time employed in main current job 0.6 0.6 2.3 -0.1 0.9 -1.5 -1.0 0.4 -0.9 0.9 0.7 1.1 -0.6 -0.1 0.2 0.7 -0.8
Alcohol intake versus 10 years previously 0.1 0.2 1.5 -0.1 0.4 -1.2 -0.3 0.3 -0.1 0.2 0.2 -0.3 0.0 -0.6 -0.0 0.0 -0.6
Father’s age at death 0.7 0.9 2.1 -0.8 -1.2 0.1 -0.7 -1.2 -0.8 -1.1 -0.9 -1.2 -0.8 -0.5 -1.1 -1.5 0.8
Worrier / anxious feelings 0.3 0.5 2.4 -0.6 0.4 -0.2 -1.0 0.4 -0.6 0.4 -0.1 -1.6 -1.4 -0.2 0.2 0.4 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.8 -0.8 -0.2 0.8 -0.7 -0.0 0.4 -0.1 -0.5 -0.7 -0.3 0.9 0.1 -0.5 0.6
Falls in the last year 0.5 0.7 2.1 0.9 0.9 0.6 0.8 1.2 1.5 0.7 0.8 0.2 0.5 0.9 0.9 0.4 -0.9
Hair/balding pattern: Pattern 3 0.7 1.0 4.0 0.8 0.2 2.0 1.1 0.4 1.1 0.4 0.5 1.0 1.5 1.4 1.0 0.3 -0.3
Number of live births 2.0 2.9 9.3 1.9 1.1 3.1 2.6 1.4 1.9 1.0 1.5 0.4 0.7 2.4 1.4 0.5 -1.5
Forced expiratory volume in 1-second (FEV1) 1.8 5.9 9.6 3.0 2.6 0.7 2.6 2.5 0.7 2.6 2.8 3.1 2.5 1.7 2.3 2.4 -2.9
Pulse rate 0.2 0.3 2.7 -0.6 0.4 -0.0 -0.9 -0.3 -0.2 0.3 0.1 -1.6 -0.5 0.0 0.2 -0.1 -0.2
Happiness 0.3 0.4 1.2 -0.2 -0.5 -1.1 -0.8 -0.7 -0.4 -0.5 -0.5 -0.7 -0.6 -1.1 -0.5 -0.1 0.3
Noisy workplace 0.8 1.0 3.1 0.6 1.3 0.3 0.6 1.5 0.4 1.1 1.0 0.4 0.7 0.6 0.9 1.8 -1.4
Qualifications: A levels/AS levels or equivalent 0.1 0.1 0.7 0.3 0.1 -0.4 -0.4 -0.4 -0.5 0.3 0.2 0.8 -0.3 0.1 0.2 0.4 -0.2
Serious illness, injury or assault of a close relative in last 2 years 2.2 2.5 4.7 -1.7 -1.6 -1.2 -2.0 -1.9 -2.2 -1.5 -1.7 -0.3 -1.5 -1.2 -1.7 -1.4 1.5
Mouth/teeth dental problems: Dentures 0.2 0.3 1.1 -0.5 -0.5 -0.1 0.0 -0.4 -0.8 -0.6 -0.6 -0.7 -1.1 -0.7 -0.5 -0.2 0.5
Asthma 0.3 0.5 2.2 -1.0 0.2 -1.0 -1.5 0.6 -0.3 0.3 -0.3 -1.1 -0.8 0.1 -0.2 0.3 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.6 -0.9 -1.1 0.4 -0.5 -0.3 -0.3 -0.9 -1.1 -1.2 -0.2 -0.3 -0.7 -1.0 1.3
Medication: Cholesterol lowering 2.2 3.4 7.4 -2.6 -1.4 -2.0 -2.7 -1.4 -1.8 -1.2 -1.9 -1.4 -2.4 -1.3 -1.8 -1.2 1.9
Depression (self-reported) 0.2 0.2 0.6 -0.6 -0.4 0.8 -0.5 -0.1 0.3 -0.7 -0.6 0.3 -0.3 0.5 -0.3 -0.3 0.5
Medication: Lansoprazole 0.1 0.1 0.3 -0.4 -0.6 0.1 -0.3 -0.1 -0.0 -0.5 -0.5 0.2 -0.1 0.0 -0.4 -0.3 0.4
Prospective memory result 0.6 0.8 2.5 1.0 0.2 1.6 1.6 0.7 1.0 0.2 0.5 -1.1 0.3 1.1 0.7 0.1 -0.4
Lung cancer (father) 1.6 1.9 3.4 -1.4 -1.6 -0.5 -1.0 -1.5 -0.7 -1.3 -1.6 -1.8 -1.3 -1.2 -1.3 -1.6 1.6
Illnesses of mother 0.0 0.1 0.3 -0.1 -0.2 0.0 -0.3 -0.2 0.0 -0.2 -0.1 -0.2 0.5 -0.1 -0.3 -0.3 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.7 5.4 9.0 3.0 2.2 1.1 2.8 2.6 1.1 2.2 2.6 2.9 2.5 1.6 2.2 2.1 -2.7
Pulse wave Arterial Stiffness index 0.7 0.8 1.7 0.4 1.3 -0.7 -0.2 1.2 0.5 1.2 1.0 0.1 1.3 0.4 0.9 0.7 -1.2
Impedance of arm (left) 0.7 3.1 14.6 2.0 0.7 -2.6 0.6 0.0 -2.1 0.5 1.5 3.8 1.7 -1.6 -0.0 0.8 -1.7
Arm fat mass (right) 0.2 0.9 3.4 0.7 1.0 1.3 1.9 1.2 0.7 0.7 0.7 -0.9 0.7 0.7 0.9 0.7 -0.7
Trunk predicted mass 0.4 2.4 6.5 -2.0 -1.2 0.0 -0.9 -1.1 -1.3 -1.1 -1.8 -2.5 -2.4 -0.1 -1.1 -1.6 1.8
Standing height 0.2 2.0 15.0 -0.1 -0.4 -2.6 -0.3 -1.0 -3.9 -0.4 -0.3 0.4 -0.6 -1.5 -1.0 -0.6 0.2
Length of working week for main job 1.1 1.3 2.6 -1.1 -1.0 -1.2 -1.5 -0.6 -1.6 -1.0 -1.1 -0.7 -0.9 -1.2 -1.1 -1.1 1.2
Exposure to tobacco smoke at home 0.3 0.3 1.6 -0.2 -0.6 0.4 0.1 -0.6 -0.3 -0.7 -0.4 -0.3 0.7 -0.1 -0.3 -1.2 0.4
Breastfed as a baby 0.3 0.4 1.8 0.4 0.1 1.4 0.3 0.3 0.6 0.3 0.3 0.9 0.8 0.9 0.4 0.3 -0.1
Tense / ‘highly strung’ 1.0 1.6 4.7 -1.0 -1.0 -1.3 -1.1 -1.5 -1.3 -1.2 -1.2 -2.2 -1.1 -1.0 -1.0 -1.1 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.6 -0.6 -0.6 0.4 -0.5 -0.3 0.3 -0.7 -0.7 -0.5 0.5 0.0 -0.3 -0.6 0.7
Hair/balding pattern: Pattern 4 0.3 0.6 1.5 -0.7 -0.4 -1.0 -0.3 -0.8 -1.1 -0.4 -0.6 -1.2 -1.1 -0.8 -0.7 -0.5 0.5
Birth weight of first child 0.2 0.3 1.3 -0.2 0.7 -0.1 -0.2 0.6 -0.6 0.7 0.3 -1.1 -0.4 0.5 0.6 0.9 -0.2
Peak expiratory flow (PEF) 0.9 2.0 3.3 1.6 1.6 0.5 1.7 1.3 0.7 1.6 1.5 1.2 1.8 1.4 1.4 1.2 -1.6
Pulse wave reflection index 0.1 0.1 0.4 -0.2 0.1 -0.6 -0.2 0.6 0.5 0.2 -0.1 -0.2 0.5 -0.2 -0.1 -0.0 -0.0
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.3 0.3 0.4 0.1 0.1 0.4 0.1 0.4 0.3 0.3 0.4 0.5 0.4 0.6 -0.2
Loud music exposure frequency 0.3 0.3 1.6 -0.3 -0.4 -0.6 -0.2 0.1 0.5 -0.4 -0.4 -1.3 0.4 -0.8 -0.4 -0.6 0.2
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.3 0.2 0.4 -0.5 -0.1 -0.4 0.4 0.5 0.4 0.3 0.5 -0.1 0.3 0.0 -0.3
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.1 0.5 0.9 0.3 0.2 1.1 0.6 0.9 0.8 -0.2 1.5 1.0 0.8 1.2 -1.0
Blood clot in the leg (DVT) 0.9 1.1 5.1 -1.1 -1.0 -0.0 -0.3 -0.9 -0.5 -1.2 -1.1 -2.3 -0.7 -0.8 -1.1 -1.0 1.2
Medication: Paracetamol 0.1 0.2 1.1 -0.4 0.2 -0.1 -0.4 0.1 0.6 0.3 -0.1 -1.0 -0.4 0.4 -0.0 -0.5 0.1
Headache pain in last month 0.2 0.3 0.7 -0.9 -0.4 -0.4 -0.7 0.3 -0.7 -0.4 -0.5 0.0 -0.3 -0.1 -0.6 -0.7 0.5
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 7.3 2.6 1.2 1.2 2.4 0.8 0.9 0.9 1.8 1.9 2.7 0.7 1.5 1.2 -1.8
Glaucoma (self-reported) 0.2 0.3 1.3 0.5 -0.1 0.8 1.2 -0.2 -0.2 -0.1 0.1 1.0 -0.5 0.5 0.2 0.1 0.0
Gout (self-reported) 0.3 0.4 2.7 0.6 0.5 -0.2 0.1 0.5 0.1 0.6 0.5 1.6 0.4 -0.0 0.5 0.8 -0.7
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.3 -0.6 0.3 -1.1 -0.8 -0.0 -1.0 0.5 -0.1 -1.0 -0.7 -0.5 -0.0 0.1 0.1
Medication: Amlodipine 0.9 1.3 4.9 -2.0 -0.5 -0.8 -2.2 -0.6 -0.4 -0.6 -1.1 -1.3 -1.5 -0.7 -1.0 -0.5 0.8
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.9 0.0 0.3 0.1 0.2 -0.0 0.6 0.3 0.2 -1.0 0.7 0.2 0.0 0.4 -0.2
Birth weight 0.1 0.3 2.2 -0.3 0.1 1.5 0.1 0.5 -0.2 0.2 -0.1 -0.4 -0.5 1.0 0.4 0.2 0.2
Chronic bronchitis/emphysema (mother) 1.6 1.8 4.3 1.1 1.4 0.9 0.9 1.5 1.6 1.4 1.2 2.1 0.3 1.3 1.4 1.7 -1.1
High blood pressure (siblings) 1.7 2.4 4.9 1.1 2.1 0.2 0.7 1.6 1.6 2.2 1.6 -1.2 1.0 1.4 1.7 2.1 -1.6
Forced vital capacity (FVC), Best measure 1.4 5.2 9.5 3.1 2.1 0.9 2.7 2.7 0.8 2.0 2.6 3.1 2.4 1.3 2.1 2.0 -2.6
Body fat percentage 0.8 3.3 8.5 2.1 1.9 1.4 2.9 2.0 1.4 1.5 1.9 0.7 2.0 0.9 1.6 1.8 -2.0
Leg fat percentage (right) 1.0 3.7 7.7 1.9 1.9 2.2 2.8 2.2 2.6 1.5 1.8 -0.0 1.6 1.7 1.8 1.9 -1.8
Arm fat-free mass (right) 0.4 2.0 9.5 -1.7 -1.1 0.3 -0.3 -0.9 -1.0 -1.1 -1.6 -3.1 -1.8 -0.2 -1.0 -1.4 1.7
Exposure to tobacco smoke outside home 0.1 0.2 0.6 0.1 -0.6 0.3 0.3 0.6 0.4 -0.4 -0.3 -0.3 0.6 -0.1 -0.2 -0.8 0.4
Comparative body size at age 10 0.2 0.5 2.2 -0.0 0.0 0.8 0.7 0.5 1.3 0.3 -0.0 -0.4 1.5 0.9 0.4 -1.0 0.2
Number of full brothers 1.5 1.9 3.6 -1.6 -0.8 -1.6 -1.6 -1.9 -0.7 -1.0 -1.2 -1.2 -1.8 -1.1 -1.4 -1.5 1.1
Worry too long after embarrassment 0.4 0.6 2.9 -0.7 -0.4 -0.3 -0.9 -0.8 -1.1 -0.5 -0.7 -0.5 -1.7 -0.8 -0.5 -0.4 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.1 0.4 -0.5 -0.2 0.1 -0.6 0.2 -0.1 -0.4 -0.5 -0.5 -0.1 0.2 -0.1 -0.4 0.5
Wheeze or whistling in the chest in last year 0.2 0.3 0.8 -0.7 -0.7 0.5 -0.2 -0.5 -0.1 -0.7 -0.8 -0.5 -0.2 0.2 -0.5 -0.9 0.7
Number of children fathered 0.4 0.4 1.1 -0.2 -0.9 0.2 0.4 -1.0 -0.5 -1.0 -0.5 0.2 -0.9 -0.3 -0.7 -0.7 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.2 0.5 0.2 -0.1 0.7 0.5 0.0 -0.4 -0.2 -0.1 0.7 -0.5 0.7 0.1 -0.4 0.0
Age at first live birth 0.2 0.4 0.9 0.8 0.4 0.4 0.9 0.5 0.2 0.6 0.6 0.8 0.5 0.2 0.6 0.5 -0.8
Pulse wave peak to peak time 0.6 0.7 1.6 -0.2 -1.2 0.5 0.4 -1.2 -0.8 -1.2 -0.9 -0.1 -1.2 -0.5 -0.8 -0.6 1.1
Health satisfaction 0.1 0.1 0.4 -0.0 0.1 0.4 0.3 -0.2 0.6 -0.2 0.0 -0.5 -0.6 0.5 -0.0 0.3 -0.1
Shortness of breath walking on level ground 0.1 0.2 1.3 0.0 0.4 -0.4 0.1 0.2 -0.0 0.3 0.2 -1.1 0.1 -0.1 0.0 0.5 -0.3
Qualifications: College or University degree 0.3 1.1 2.9 -0.8 -0.7 -1.3 -1.2 -0.9 -1.7 -0.6 -0.8 -1.1 -0.7 -1.4 -0.8 -0.9 0.9
Eye problems/disorders: None of the above 2.8 3.2 4.9 1.9 1.7 1.2 1.8 1.5 2.2 1.8 1.8 1.8 1.9 1.6 2.0 1.9 -1.7
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.1 0.2 -0.7 1.5 1.1 -0.1 0.7 -0.6 -0.5 -1.1 1.3 0.9 -0.0 -1.1 0.7
Emphysema/chronic bronchitis 0.3 0.4 1.1 -0.5 -1.0 0.2 -0.1 -0.4 -0.0 -1.1 -0.9 -0.1 0.1 -0.6 -0.7 -0.6 0.9
Medication for pain relief, constipation, heartburn 0.9 1.5 3.7 1.7 1.3 -0.2 1.3 0.7 0.3 1.1 1.6 1.9 0.8 -0.2 1.1 1.6 -1.7
Neck or shoulder pain in last month 1.9 2.7 4.3 1.5 1.9 1.8 1.6 1.5 1.9 1.7 1.8 0.3 0.7 2.1 1.8 1.8 -1.6
Medication: Blood pressure 0.7 1.2 5.9 -1.8 -0.7 -0.5 -1.6 -0.2 -0.2 -0.4 -1.1 -0.8 -2.4 -0.2 -0.8 -0.6 1.1
Angina (self-reported) 1.3 1.7 5.8 -1.3 -1.5 0.5 -0.3 -1.3 -0.2 -1.4 -1.6 -2.4 -1.0 -0.4 -1.0 -1.5 1.7
Migraine (self-reported) 0.3 0.4 1.5 -0.1 0.6 0.4 0.1 1.2 1.2 0.8 0.4 -0.2 0.3 0.9 0.6 0.3 -0.3
Medication: Ibuprofen 0.9 1.1 2.6 -0.9 -1.3 0.2 -0.6 -0.9 -0.6 -1.1 -1.3 -1.6 0.1 -0.3 -0.9 -1.6 1.4
Medication: Allopurinol 0.1 0.1 0.6 0.0 -0.1 -0.4 -0.4 0.0 -0.3 -0.2 -0.0 0.8 0.3 -0.5 -0.2 -0.2 -0.2
Medication: Omeprazole 0.6 0.7 2.6 0.9 0.6 0.7 1.0 0.5 1.6 0.7 0.7 -0.6 0.6 1.0 1.0 0.7 -0.4
Medication: Seretide 50 evohaler 0.8 1.0 2.9 -1.1 -0.5 -1.7 -1.2 -0.6 -0.6 -0.7 -0.9 -0.8 -0.8 -1.6 -0.9 -1.0 0.5
Mean time to correctly identify matches 1.1 2.1 3.6 -1.2 -1.3 -1.5 -1.2 -1.0 -1.9 -1.4 -1.4 -1.7 -1.2 -1.8 -1.3 -1.8 1.2
Heart disease (mother) 0.3 0.4 2.1 0.3 0.3 1.5 0.6 0.6 0.1 0.4 0.2 0.1 -0.9 0.8 0.7 0.8 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 3.6 1.0 1.2 -0.3 0.4 1.1 0.7 1.2 1.1 0.2 1.9 0.2 1.0 1.0 -1.2
Whole body fat mass 0.3 1.2 4.5 1.1 1.2 1.0 2.1 1.4 0.5 0.9 1.0 -0.2 1.2 0.5 0.9 0.9 -1.1
Leg fat mass (right) 0.4 1.6 5.3 1.1 1.1 1.7 2.3 1.5 1.4 0.8 1.0 -0.5 1.0 1.1 1.0 1.0 -1.0
Arm predicted mass (right) 0.4 2.0 8.2 -1.8 -1.2 0.3 -0.3 -0.9 -0.9 -1.2 -1.7 -2.9 -1.6 -0.3 -1.1 -1.6 1.8
Pulse rate, automated reading 0.6 1.8 8.8 -2.0 0.3 -0.5 -2.6 -0.1 -0.2 0.5 -0.5 -3.0 -2.2 -0.1 -0.1 -0.2 0.5
Alcohol intake frequency. 1.0 2.2 3.8 -1.8 -0.9 -1.7 -1.8 -1.0 -2.0 -0.9 -1.3 -1.8 -1.7 -1.8 -1.4 -1.0 1.0
Comparative height size at age 10 0.3 1.7 10.0 -0.3 0.6 -3.2 -1.2 0.3 -2.8 0.8 0.3 0.3 -0.3 -1.6 -0.2 0.6 -0.4
Number of full sisters 1.0 1.2 5.7 0.7 0.8 2.4 1.1 0.8 1.4 0.7 0.8 -1.1 0.6 1.5 1.2 0.4 -0.7
Suffer from ‘nerves’ 0.0 0.1 0.2 -0.3 0.0 0.2 -0.4 0.2 0.5 -0.1 -0.1 0.1 0.2 0.3 -0.0 0.2 0.1
Overall health rating 1.7 3.7 11.3 -2.5 -1.7 -0.5 -2.2 -1.4 -0.5 -1.7 -2.1 -3.4 -2.2 -1.1 -1.6 -1.8 2.1
Chest pain or discomfort 1.0 1.5 7.5 -1.1 -1.3 0.1 -0.9 -0.4 -0.2 -1.3 -1.5 -2.7 0.8 -0.4 -1.0 -1.5 1.4
Had major operations 0.1 0.1 0.5 -0.1 0.4 -0.4 -0.3 0.1 0.4 0.5 0.0 -0.6 -0.3 0.0 0.2 0.7 0.0
Age at last live birth 0.7 1.0 3.1 1.2 0.6 1.6 1.8 0.5 1.0 0.7 0.9 0.8 -0.1 1.2 0.9 0.4 -0.9
Family relationship satisfaction 0.4 0.5 1.7 -0.2 -0.2 -0.8 -0.7 0.0 -0.9 -0.2 -0.3 -1.3 -1.2 -0.9 -0.3 -0.3 0.2
Leg pain on walking 1.6 2.0 3.8 -1.3 -1.9 -0.3 -0.8 -1.8 -0.7 -2.0 -1.7 -0.4 -1.1 -1.0 -1.6 -1.9 1.7
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.1 -0.6 -0.9 -0.5 -0.4 -0.7 -0.7 -0.9 -0.9 -0.8 -0.9 -0.6 -0.8 -1.0 0.8
Commuting to job workplace: Car/motor vehicle 2.0 2.3 3.6 1.5 1.6 0.8 1.8 1.8 1.9 1.5 1.5 1.1 0.8 1.9 1.4 1.5 -1.6
Illness, injury, bereavement, stress in last 2 years 3.4 4.2 7.0 2.1 2.5 0.3 1.2 2.2 1.6 2.6 2.5 1.8 2.0 1.1 2.3 2.6 -2.4
Medication: Aspirin 0.8 1.0 2.2 -1.5 -1.1 -0.3 -1.1 -0.8 -0.8 -1.1 -1.3 -0.5 -1.2 0.1 -1.1 -1.0 1.3
Supplements: Vitamin C 0.3 0.3 1.8 -0.1 0.5 -0.3 -0.5 1.4 0.5 0.7 0.3 -0.2 0.5 0.6 0.5 0.6 -0.2
Knee pain experienced in last month 0.6 1.0 4.2 -1.5 -0.7 0.5 -0.5 -0.5 -0.3 -0.9 -1.1 -2.1 -1.3 0.1 -0.8 -0.4 1.1
Hypertension (Self-reported) 0.3 0.9 5.3 -1.2 -0.4 -0.4 -0.8 -0.2 0.2 -0.5 -0.9 -2.3 -1.4 -0.2 -0.7 -0.9 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.7 3.2 9.5 2.2 1.0 2.4 1.9 1.2 2.0 1.0 1.4 1.3 3.1 2.1 1.9 0.8 -1.3
Illnesses of father: Heart disease 2.4 3.4 6.0 2.0 2.1 0.6 1.4 2.3 1.5 2.1 2.0 0.6 2.5 1.5 2.0 1.9 -2.1
Illnesses of siblings: Diabetes 0.9 1.1 3.4 -1.1 -0.3 -1.2 -1.6 -0.9 -1.7 -0.3 -0.7 -1.8 -0.2 -0.9 -0.8 -0.1 0.6
Smoking status: Previous 0.8 1.2 2.8 0.5 1.4 0.4 -0.1 1.7 0.7 1.5 1.0 -0.3 -0.2 1.5 1.2 1.5 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.2 -0.2 -0.6 -1.3 -0.3 -0.7 -1.5 -0.7 -0.6 -0.3 -0.5 -0.9 -1.0 -0.8 0.5
Whole body fat-free mass 0.4 2.2 7.1 -1.9 -1.2 -0.1 -0.6 -1.0 -1.6 -1.2 -1.7 -2.7 -1.9 -0.4 -1.1 -1.6 1.8
Leg fat-free mass (right) 0.3 1.6 5.6 -1.6 -0.8 -0.3 -0.3 -0.7 -2.0 -0.8 -1.3 -2.4 -1.4 -0.6 -1.0 -1.3 1.4
Arm fat percentage (left) 0.4 1.4 5.0 1.2 1.2 1.4 2.2 1.4 0.9 0.9 1.1 -0.0 1.2 0.6 1.1 1.0 -1.2
Average weekly red wine intake 0.6 0.8 3.5 1.1 0.5 1.1 1.1 0.4 1.2 0.6 0.7 0.3 1.9 0.6 1.1 0.5 -0.4
Handedness (chirality/laterality): Left-handed 1.2 1.5 3.3 1.4 0.8 1.3 1.3 1.2 1.1 1.1 1.1 1.8 1.5 1.1 1.4 0.6 -1.0
Mood swings 0.3 0.5 4.4 -0.3 0.1 0.4 -0.5 -0.5 0.9 0.1 -0.2 -2.1 -0.9 0.2 0.1 -0.5 0.1
Loneliness, isolation 0.6 0.8 1.7 0.7 1.3 0.3 0.5 0.6 1.3 1.3 1.0 -0.1 0.7 0.8 1.3 0.7 -1.1
Long-standing illness, disability or infirmity 1.7 2.6 4.5 -2.1 -1.6 -1.0 -1.8 -1.3 -1.0 -1.6 -1.9 -1.9 -1.7 -1.5 -1.5 -1.5 1.9
Ever had bowel cancer screening 0.6 0.7 1.4 -0.7 -1.2 0.4 0.0 -0.9 -1.0 -1.1 -1.0 -0.9 0.3 -0.9 -0.7 -0.9 1.2
Diabetes diagnosed by doctor 2.1 3.5 5.2 -2.1 -1.8 -2.0 -2.3 -2.0 -1.8 -1.6 -2.0 -1.0 -1.8 -2.2 -1.9 -1.5 1.9
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 2.7 0.6 0.3 1.7 0.7 0.7 1.2 0.5 0.4 -0.2 0.4 1.6 0.7 0.2 -0.3
Friendships satisfaction 1.4 1.7 3.7 1.3 1.9 -0.2 0.4 1.7 0.9 1.9 1.6 0.5 0.4 0.6 1.5 1.6 -1.9
Qualifications: nursing, teaching 1.5 2.3 4.8 1.6 2.0 0.1 0.7 1.8 1.2 2.2 1.9 0.8 0.9 0.7 1.9 1.6 -1.9
Commuting to job workplace: Walk 1.6 1.7 4.3 -1.1 -1.1 -2.1 -1.9 -0.8 -1.5 -0.9 -1.2 -1.4 0.1 -1.5 -1.5 -1.2 0.9
Eye problems/disorders: Cataract 2.0 2.3 3.3 -1.8 -1.7 -0.4 -1.3 -1.2 -1.6 -1.8 -1.8 -1.7 -1.1 -1.0 -1.7 -1.8 1.6
Mouth/teeth dental problems: Mouth ulcers 1.7 2.7 6.3 -1.4 -1.6 -1.4 -1.0 -1.9 -1.1 -1.8 -1.7 -2.5 -1.1 -2.0 -1.8 -1.7 1.5
Medication for cholesterol 1.6 2.5 5.8 2.0 1.7 0.2 1.6 1.5 0.1 1.6 1.8 2.4 1.5 0.5 1.6 1.8 -1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.3 -0.3 -0.8 0.5 0.5 -0.8 0.7 -0.9 -0.6 -1.1 1.0 -0.4 -0.6 -0.7 0.7
Back pain experienced in last month 0.2 0.2 1.0 -0.5 -0.3 0.5 -0.2 -0.1 0.6 -0.5 -0.5 -1.0 -0.4 0.6 -0.3 -0.4 0.3
Mineral and other dietary supplements 2.5 3.4 5.1 -1.4 -1.9 -1.7 -1.2 -2.2 -2.2 -1.9 -1.9 -1.0 -1.4 -2.2 -1.9 -2.1 1.9
Breast cancer (self-reported) 1.7 2.0 4.2 -1.7 -2.0 -0.0 -1.2 -1.8 -1.3 -2.0 -1.8 0.6 -0.7 -0.7 -1.6 -0.8 1.9
Asthma (self-reported) 0.2 0.4 1.7 -0.9 0.2 -0.8 -1.3 0.5 -0.2 0.2 -0.3 -1.0 -0.8 0.3 -0.2 0.2 0.1
Osteoporosis (self-reported) 0.8 1.0 4.2 -1.1 -0.4 -1.4 -1.6 -0.3 -0.5 0.0 -0.7 -1.2 -2.0 -0.7 -0.5 -0.2 0.8
Osteoarthritis (self-reported) 0.2 0.3 2.3 -0.0 0.3 0.7 0.1 0.6 0.6 0.3 0.1 -1.5 0.4 0.1 0.6 0.1 -0.0
Medication: Aspirin 0.2 0.3 0.7 -0.7 -0.6 0.4 -0.5 -0.3 -0.1 -0.7 -0.8 -0.4 -0.2 0.5 -0.5 -0.4 0.8
Medication: Gliclazide 3.5 4.0 6.4 -2.5 -1.9 -1.7 -2.0 -2.1 -2.1 -1.9 -2.1 -1.5 -2.5 -1.5 -2.1 -1.6 2.1
Illnesses of father: None of the above (group 1) 0.9 1.1 5.5 -0.5 -1.1 0.6 0.3 -1.5 -0.4 -1.3 -0.8 0.6 -2.3 -0.1 -1.0 -1.1 0.9
Smoking status: Current 0.5 0.8 4.1 0.9 -0.2 0.7 1.4 0.2 1.1 -0.3 0.2 1.2 2.0 0.4 0.2 -0.7 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.2 3.7 1.9 1.4 1.4 1.9 1.0 1.4 1.4 1.6 0.8 1.6 1.2 1.6 1.4 -1.7
Whole body water mass 0.3 2.0 6.7 -1.8 -1.0 -0.1 -0.6 -0.9 -1.6 -1.0 -1.6 -2.6 -1.9 -0.4 -1.0 -1.5 1.7
Leg predicted mass (right) 0.3 1.6 5.4 -1.5 -0.8 -0.3 -0.3 -0.7 -2.0 -0.8 -1.3 -2.3 -1.4 -0.6 -1.0 -1.3 1.4
Arm fat mass (left) 0.2 0.7 3.2 0.5 0.7 1.2 1.8 1.1 0.6 0.5 0.5 -1.0 0.7 0.4 0.7 0.3 -0.5
Number of self-reported non-cancer illnesses 2.4 4.1 12.3 -2.8 -1.8 -0.5 -2.0 -1.2 -1.3 -1.9 -2.4 -3.5 -1.9 -0.6 -1.9 -2.3 2.3
Average weekly champagne plus white wine intake 0.4 0.5 1.8 -0.3 -0.8 -0.6 -0.3 -0.4 -0.5 -1.0 -0.6 -0.3 -0.8 -0.6 -1.0 -1.3 0.5
Miserableness 0.8 1.3 3.5 -1.1 -0.9 -0.7 -1.6 -1.7 -0.9 -1.0 -1.1 -1.9 -0.8 -0.6 -1.0 -0.9 1.0
Guilty feelings 0.4 0.6 1.2 -0.6 -0.7 0.5 -0.7 -0.8 -0.6 -0.7 -0.8 -0.9 -1.1 -0.2 -0.4 -1.0 0.9
Wears glasses or contact lenses 0.3 0.3 2.2 -0.1 -0.3 -0.3 -0.1 -0.5 -0.3 -0.3 -0.4 -1.5 0.0 -0.6 -0.1 -1.0 0.3
Ever taken oral contraceptive pill 0.6 0.7 2.7 -1.3 -0.5 -0.6 -1.6 -0.4 0.3 -0.4 -0.8 -0.5 -0.9 -0.3 -0.8 -0.7 0.8
Hearing aid user 0.6 0.7 1.5 -0.7 -0.9 -1.2 -0.8 -0.6 -0.7 -0.7 -0.8 0.3 -1.2 -0.7 -0.8 -0.9 0.9
Mother’s age at death 1.8 2.2 4.3 1.8 1.2 2.1 1.7 1.2 0.8 1.4 1.5 1.7 1.0 1.9 1.8 0.9 -1.3
Financial situation satisfaction 0.5 0.6 1.4 -1.1 -1.0 -0.2 -0.8 -0.4 -0.3 -0.9 -1.1 -1.1 -0.2 -0.1 -0.8 -0.8 1.2
Tinnitus: Yes, now most or all of the time 0.7 0.8 4.4 0.6 0.4 0.8 0.6 1.0 0.5 0.4 0.7 2.1 1.1 0.9 0.6 0.3 -0.5
Commuting to job workplace: Public transport 3.7 4.4 6.9 -2.1 -1.9 -2.4 -2.4 -2.2 -1.8 -1.8 -2.0 -1.8 -1.8 -2.6 -2.1 -2.0 2.1
Eye problems/disorders: Glaucoma 0.3 0.3 0.8 -0.0 -0.6 0.3 0.8 -0.8 -0.9 -0.7 -0.4 0.3 -0.8 0.0 -0.5 -0.6 0.6
Medication: Blood pressure 1.7 3.3 7.5 -2.1 -1.9 -0.6 -1.3 -1.6 -0.3 -2.1 -2.1 -2.7 -1.9 -1.0 -2.1 -2.1 2.0
Pain type(s) experienced in last month: Hip pain 0.5 0.7 4.7 -0.9 -0.6 0.4 -0.5 -0.4 -0.2 -0.4 -0.9 -2.2 -0.7 -0.1 -0.2 -0.4 1.1
Supplements: Fish oil (including cod liver oil) 1.4 1.8 2.9 1.1 1.3 1.7 0.9 1.6 1.4 1.2 1.4 0.6 1.3 1.5 1.4 1.3 -1.4
High cholesterol (Self-reported) 1.2 2.2 5.2 -2.3 -0.8 -1.4 -2.2 -1.4 -0.8 -0.6 -1.5 -2.3 -1.8 -0.8 -1.2 -0.5 1.4
Medication: Bendroflumethiazide 0.6 0.8 3.4 -1.4 -0.1 -0.7 -1.0 -0.4 0.0 -0.1 -0.6 -1.8 -1.7 -0.7 -0.6 -0.3 0.7
Medication: Paracetamol 0.3 0.5 1.6 -1.0 -0.4 -0.5 -0.9 -0.5 -0.1 -0.2 -0.6 -1.3 -0.7 -0.0 -0.6 -1.0 0.7
Medication: Lisinopril 0.3 0.3 1.1 -0.7 -0.5 -0.1 -0.3 -0.8 0.4 -0.5 -0.6 -1.1 -0.1 -0.7 -0.6 -0.3 0.6
Medication: Atorvastatin 1.2 1.5 4.8 -1.4 -1.1 -1.0 -1.0 -1.1 -0.3 -1.0 -1.3 -2.2 -0.8 -1.4 -1.3 -1.0 1.4
Illnesses of father: High blood pressure 0.4 0.5 2.5 -0.4 0.4 -1.6 -1.2 0.2 -0.4 0.7 0.0 -1.4 -0.1 -0.6 0.1 0.1 -0.2
Alcohol drinker status: Never 0.5 0.7 3.0 -0.7 -0.4 -1.7 -0.8 -0.2 -1.0 -0.3 -0.4 0.2 -0.8 -1.3 -0.7 -0.9 0.3
Ever smoked 0.7 1.2 3.2 0.9 1.3 0.5 0.6 1.8 1.1 1.4 1.1 0.2 1.0 1.1 1.2 0.9 -1.2
Basal metabolic rate 0.2 1.2 5.3 -1.3 -0.6 0.1 -0.1 -0.5 -1.2 -0.7 -1.2 -2.3 -1.4 -0.2 -0.7 -1.1 1.2
Leg fat percentage (left) 0.9 3.2 6.1 1.5 1.8 2.1 2.4 2.1 2.5 1.5 1.6 -0.5 1.4 1.7 1.6 1.9 -1.6
Arm fat-free mass (left) 0.2 1.2 7.7 -1.3 -0.5 0.6 -0.1 -0.4 -0.3 -0.4 -1.1 -2.8 -1.5 0.4 -0.4 -0.8 1.1
Number of operations (self-reported) 0.4 0.6 2.7 0.1 0.7 0.4 0.2 1.0 0.9 0.8 0.2 -1.6 1.0 1.0 0.7 0.2 -0.3
Average weekly beer plus cider intake 0.3 0.5 1.5 0.6 0.5 0.3 1.0 -0.1 0.7 0.2 0.5 1.2 -0.4 1.2 0.2 0.7 -0.6
Irritability 0.3 0.6 1.9 0.6 0.5 1.4 0.9 0.0 0.9 0.3 0.4 -1.1 -0.5 1.2 0.7 0.1 -0.4
Risk taking 0.5 0.7 3.6 -0.3 -1.1 0.1 0.1 -0.8 0.5 -1.1 -0.8 0.5 0.3 -0.1 -0.9 -1.9 0.9
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.5 -0.3 -0.6 -1.1 -0.5 -0.4 -0.0 -0.6 -0.6 -1.2 0.1 -1.2 -0.7 -0.7 0.4
Fractured/broken bones in last 5 years 0.4 0.6 2.8 -0.1 0.9 0.2 -0.4 1.0 0.2 1.0 0.4 -1.7 -0.3 0.3 0.9 0.9 -0.4
Age started oral contraceptive pill 0.6 0.8 2.9 -1.0 -0.9 -0.3 -0.5 -0.7 -0.8 -0.8 -1.0 -1.7 -0.2 -0.5 -0.7 -1.3 1.1
Diastolic blood pressure, automated reading 0.1 0.4 1.1 0.8 0.7 -0.3 1.0 0.1 0.9 0.7 0.7 -0.4 0.3 0.1 0.4 1.0 -0.6
Ever depressed for a whole week 1.3 1.6 3.2 -1.5 -1.1 -1.3 -1.7 -0.7 -1.8 -1.2 -1.3 -1.4 -0.2 -1.4 -1.4 -0.9 1.2
Unable to work because of sickness or disability 0.5 0.6 2.1 -0.7 -0.8 0.2 0.3 -0.6 0.1 -0.8 -0.8 -1.4 -1.4 -0.0 -0.8 -0.6 1.0
Commuting to job workplace: Cycle 1.6 1.9 4.0 1.2 1.5 1.7 1.5 1.0 0.6 1.6 1.6 0.5 0.5 1.4 1.5 2.0 -1.4
Myopia 0.7 1.0 3.0 1.3 0.5 1.2 1.7 0.5 1.1 0.5 0.9 0.9 1.7 0.7 0.9 0.3 -0.7
Vascular/heart problems diagnosed by doctor 0.7 2.0 6.0 1.8 1.3 0.5 1.1 0.8 -0.0 1.3 1.6 2.4 1.8 0.4 1.4 2.0 -1.6
Cholesterol lowering medication 2.1 3.2 5.0 -2.2 -2.0 -0.6 -1.7 -2.1 -0.6 -1.9 -2.2 -2.2 -1.2 -1.1 -1.6 -1.9 2.2
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 3.5 1.2 0.7 0.9 1.4 0.6 1.9 0.9 0.9 0.0 1.1 1.3 1.0 1.0 -0.6
Pain experienced in last month 0.3 0.5 2.1 1.3 0.2 -0.3 0.4 0.2 -0.0 0.5 0.7 1.4 1.0 -0.5 0.6 0.3 -0.7
Supplements: Calcium 2.5 2.8 4.6 1.6 1.8 1.1 1.4 2.1 1.1 2.0 1.8 1.8 0.4 1.6 2.1 2.0 -1.6
Basal cell carcinoma (self-reported) 0.8 0.9 3.2 -1.4 -0.6 -1.6 -1.8 -0.4 -0.3 -0.3 -1.0 -0.8 -0.2 -1.1 -0.9 -0.3 0.9
Heart attack/myocardial infarction (self-reported) 0.4 0.6 1.9 -0.8 -0.9 0.1 -0.3 -0.2 0.2 -0.9 -1.0 -1.4 0.1 -0.3 -0.7 -1.1 0.9
Deep venous thrombosis (DVT) (self-reported) 1.1 1.5 5.7 -1.3 -1.1 -0.4 -0.7 -1.0 -0.8 -1.2 -1.3 -2.4 -0.9 -1.1 -1.2 -1.1 1.3
Heart disease (siblings) 4.9 6.0 12.4 -3.2 -2.0 -2.7 -3.5 -1.7 -3.1 -1.9 -2.6 -1.3 -2.2 -2.7 -2.4 -1.6 2.5
Alcohol drinker status: Previous 1.6 1.8 4.6 -1.5 -0.8 -2.1 -1.7 -0.9 -1.4 -0.8 -1.2 -1.8 -1.0 -1.8 -1.2 -0.9 1.1
Pack years of smoking 1.5 2.2 4.7 -1.3 -1.9 0.1 -0.5 -1.4 -0.7 -2.2 -1.9 -1.9 -0.5 -0.9 -1.6 -2.0 1.9
Impedance of whole body 0.8 3.9 13.8 2.7 1.6 -2.0 1.1 0.7 -0.7 1.5 2.4 3.7 2.3 -0.7 0.9 1.9 -2.6
Leg fat mass (left) 0.4 1.5 4.7 1.0 1.2 1.6 2.2 1.5 1.3 0.9 1.0 -0.8 1.0 1.1 1.0 1.1 -1.0
Arm predicted mass (left) 0.2 1.2 8.2 -1.4 -0.4 0.7 -0.2 -0.4 -0.3 -0.4 -1.1 -2.9 -1.6 0.4 -0.3 -0.9 1.1