TWAS hub - CCDC141

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.082	0.0300	2.6e-03	0.008	0.014	0.014	0.016	0.017	3.0e-02	7.3e-03	7.0e-03	0.0046	3.3e-03
2	TCGA	Brain Lower Grade Glioma	0.105	0.0343	4.9e-08	0.054	0.059	0.060	NA	0.066	9.1e-07	3.0e-07	2.2e-07	NA	6.2e-08
3	TCGA	Liver Hepatocellular Carcinoma	0.207	0.0750	3.0e-04	0.088	0.084	0.060	NA	0.083	6.4e-05	8.6e-05	8.4e-04	NA	1.0e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Tinnitus: Yes, but not now, but have in the past	6.4	6.8	11.2	-0.0	-3.0	-3.4
Pulse rate, automated reading	4.6	14.9	43.8	-1.0	0.2	6.6
Pulse rate	4.5	7.6	21.3	-1.1	-0.6	4.6
Rheumatoid Arthritis	3.2	4.4	7.0	2.6	2.4	0.7
Noisy workplace	3.2	3.9	5.1	-2.2	-2.1	-1.5
Pulse wave reflection index	3.1	3.8	9.9	3.1	0.3	-1.2
Emphysema/chronic bronchitis	3.1	3.5	5.0	-0.6	2.2	2.2
Had other major operations	3.0	3.7	9.9	-3.1	0.2	-1.0
Myopia	2.8	4.1	9.5	0.8	3.1	1.4
Medication: Gliclazide	2.7	3.0	6.7	1.1	-1.0	2.6
Tinnitus: Yes, now most or all of the time	2.7	3.2	5.9	-1.5	2.4	1.2
Other serious medical condition/disability diagnosed by doctor	2.5	3.3	8.5	-2.9	-0.6	1.0
Pulse wave Arterial Stiffness index	2.5	2.9	8.1	2.8	0.4	0.7
Pulse wave peak to peak time	2.3	2.8	7.4	-2.7	-0.4	-0.8
Illnesses of father: None of the above (group 1)	2.3	2.9	5.2	1.6	-2.3	-0.9
Supplements: Calcium	2.2	2.5	5.4	-2.3	1.3	-0.5
HbA1C	2.0	2.2	3.8	1.0	-1.4	-1.9
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	5.0	-1.4	2.2	0.6
Leg pain on walking	2.0	2.5	7.0	2.6	0.2	-0.7
Medication: Aspirin	2.0	2.6	5.9	-1.4	-2.4	0.1
Medication: Atenolol	1.9	2.3	4.9	2.2	0.2	1.4
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	4.0	1.6	1.5	2.0
Had major operations	1.9	2.3	2.5	1.4	1.6	-1.5
Knee pain experienced in last month	1.9	3.0	7.0	2.6	1.3	-0.5
Long-standing illness, disability or infirmity	1.9	2.8	3.3	-1.5	-1.8	1.7
Shortness of breath walking on level ground	1.8	2.1	4.0	1.3	-0.8	-2.0
Asthma	1.7	3.4	8.9	-0.2	1.1	3.0
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	3.9	2.0	1.2	-0.1
High blood pressure (mother)	1.6	2.3	4.3	2.1	0.1	1.6
Supplements: Vitamin C	1.6	1.9	4.9	-0.6	-2.2	-0.7
Schizophrenia vs Biploar Disorder	1.5	2.0	3.8	-1.9	-1.4	-0.3
Ovarian Cancer	1.5	2.0	3.6	1.9	1.0	-1.2
Ulcerative Colitis	1.5	2.1	3.7	0.9	1.4	1.9
Hearing difficulty/problems: Yes	1.5	2.3	5.9	-0.7	-0.7	2.4
Qualifications: None of the above	1.5	3.1	8.1	-0.0	-2.8	-1.1
Financial difficulties in last 2 years	1.5	2.0	2.9	1.6	1.7	0.8
Mean time to correctly identify matches	1.5	2.9	8.1	-0.6	-0.6	-2.9
Asthma (self-reported)	1.5	3.1	7.9	0.0	1.2	2.8
Reaction Time	1.4	2.8	7.9	0.0	-0.6	-2.8
Age at First Birth	1.4	2.0	2.4	-1.4	-1.5	-1.3
Vitamin and mineral supplements	1.4	1.8	3.1	1.4	1.8	0.7
Medication: Co-codamol	1.4	1.6	2.8	0.4	1.7	1.4
Severe depression (siblings)	1.4	1.5	4.0	-0.7	-0.1	2.0
Fluid intelligence score	1.4	2.9	7.0	-0.8	1.0	2.6
Time employed in main current job	1.4	1.6	2.4	-1.5	1.6	-0.4
Headache pain in last month	1.4	2.5	4.7	-0.5	1.6	2.2
Heart disease (mother)	1.4	1.6	3.5	-0.4	-1.9	1.1
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	2.1	1.3	-1.1	-1.5
Ulcerative Colitis (UC)	1.3	2.5	5.8	0.4	1.2	2.4
Alcohol intake versus 10 years previously	1.3	1.9	5.6	2.4	0.4	-0.1
Breastfed as a baby	1.3	1.7	4.1	-0.5	-0.8	2.0
Medication: Amlodipine	1.3	1.8	3.0	-1.5	-1.7	0.1
Medication: Aspirin	1.3	1.6	3.9	-0.9	-2.0	0.5
Financial situation satisfaction	1.3	1.6	1.7	1.3	-1.3	1.2
Lung FVC	1.2	5.9	15.5	-1.1	3.9	1.0
Trunk fat percentage	1.2	4.8	9.1	3.0	-1.5	-1.8
Loud music exposure frequency	1.2	1.3	2.3	-0.8	1.5	1.0
Medication: Allopurinol	1.2	1.6	4.5	-0.5	-2.1	0.1
Number of self-reported non-cancer illnesses	1.2	2.1	5.9	-0.5	0.5	2.4
Miserableness	1.2	2.1	4.1	0.1	2.0	1.4
Number of treatments/medications taken	1.1	2.0	5.0	-0.6	0.7	2.2
Diabetes (father)	1.1	1.3	1.5	-1.2	1.0	1.2
Hearing difficulty/problems with background noise	1.1	1.7	5.0	0.2	-0.1	2.2
Pain all over the body in last month	1.1	1.2	1.8	1.3	-1.2	-0.5
Father’s age at death	1.1	1.5	2.4	-1.5	-1.0	-1.0
Depression (self-reported)	1.1	1.3	2.1	-0.9	0.9	-1.5
Medication: Lansoprazole	1.1	1.2	3.1	-0.7	-1.8	-0.4
Impedance of arm (left)	1.1	5.0	8.9	3.0	-2.2	1.2
Gout (self-reported)	1.1	1.5	2.9	0.7	-1.7	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	1.9	-1.4	-1.4	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	3.9	-0.5	2.0	-0.1
Pain experienced in last month	1.1	1.8	5.3	-2.3	-0.2	-0.2
Irritable Bowel Disease (IBD)	1.0	2.4	5.3	0.4	1.2	2.3
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.2	-0.3	-1.5	-1.0
Medication for hormone replacement therapy	1.0	1.1	2.1	0.9	1.5	0.5
Serious illness, injury or assault to yourself	1.0	1.2	3.4	-1.8	0.2	0.4
Waist circumference	1.0	3.7	6.1	2.2	-0.6	-2.5
Mouth/teeth dental problems	1.0	1.5	2.3	-1.5	-0.1	1.5
Body fat percentage	1.0	4.0	7.7	2.8	-1.3	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	3.9	0.8	1.3	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.7	1.1	-0.9	-1.3
Breast cancer (self-reported)	1.0	1.2	2.8	-0.9	1.7	-0.0
Commuting to job workplace: Public transport	1.0	1.2	2.3	1.1	0.4	1.5
Heart disease (siblings)	1.0	1.2	1.8	-0.1	-1.3	-1.3
Impedance of whole body	1.0	4.9	6.9	2.6	-2.0	1.9
Alzheimer’s Disease (in mother)	0.9	1.1	3.0	-1.7	0.4	-0.4
Crohns Disease (2012)	0.9	1.5	3.8	-0.9	1.9	0.2
Lupus	0.9	1.3	2.0	-0.0	1.4	1.4
Waist Hip Ratio (WHR)	0.9	3.8	4.4	1.8	-2.1	-2.0
Hand grip strength (left)	0.9	2.4	5.0	-1.4	2.2	-0.6
Taking other prescription medications	0.9	1.3	3.9	-0.1	0.3	2.0
Supplements: Glucosamine	0.9	1.2	3.5	-1.9	-0.1	0.1
Impedance of arm (right)	0.9	4.3	7.0	2.6	-1.6	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	3.1	0.5	-0.9	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.4	1.2	1.5	-0.5
Peak expiratory flow (PEF)	0.9	2.2	3.3	-0.9	1.8	1.5
Glaucoma (self-reported)	0.9	1.1	2.3	-0.5	-1.5	-0.9
Leg fat percentage (right)	0.9	3.1	5.0	2.2	-1.2	-1.8
Exposure to tobacco smoke outside home	0.9	1.2	3.2	1.8	-0.6	0.0
Wheeze or whistling in the chest in last year	0.9	1.6	3.0	-1.3	-0.4	1.7
Angina (self-reported)	0.9	1.2	2.4	0.6	-1.0	1.5
Arm fat percentage (left)	0.9	3.7	6.6	2.6	-0.8	-1.9
Loneliness, isolation	0.9	1.2	2.5	0.7	0.8	1.6
Friendships satisfaction	0.9	1.1	2.3	1.5	0.4	-1.0
Ever taken oral contraceptive pill	0.9	1.0	1.9	1.0	-0.0	-1.4
Fractured/broken bones in last 5 years	0.9	1.1	1.4	1.2	-0.9	1.1
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.8	-0.1	1.3	2.4
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.6	0.3	1.0	-1.3
Chronotype (morning person)	0.8	1.9	3.1	1.6	-1.8	-0.4
Average weekly spirits intake	0.8	1.0	1.7	-1.2	-0.3	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	2.7	1.6	1.0	1.3
Multivitamins +/- minerals	0.8	1.1	2.6	-1.6	-0.7	-0.5
Trunk fat mass	0.8	3.6	6.0	2.4	-1.2	-1.8
Prospective memory result	0.8	0.9	1.7	-0.8	-1.3	-0.7
Length of working week for main job	0.8	0.9	2.3	-0.5	-1.5	-0.1
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.0	1.4	0.9	0.6
Birth weight	0.8	1.6	1.8	-1.2	1.4	-1.3
Medication: Ibuprofen	0.8	1.0	2.2	-0.9	0.1	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.1	1.5	-0.7	-0.4
Medication for cholesterol	0.8	1.2	2.4	-1.5	0.1	-1.1
Average weekly champagne plus white wine intake	0.8	1.1	1.7	-1.3	-0.9	-0.9
Ever smoked	0.8	1.4	3.5	-0.7	1.9	0.4
Number of operations (self-reported)	0.8	1.3	3.2	-0.7	1.8	0.2
Risk taking	0.8	1.2	2.4	-1.5	1.0	-0.4
Schizophrenia (2018)	0.7	1.5	4.2	-2.1	-0.1	0.5
Triglycerides	0.7	1.1	1.9	1.1	-0.6	-1.4
Relative age of first facial hair	0.7	1.4	1.6	-1.0	1.2	1.3
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.3	1.1	0.0	1.1
Chronic bronchitis/emphysema (father)	0.7	0.8	1.4	0.9	0.2	1.2
Forced vital capacity (FVC)	0.7	2.5	3.5	-1.5	1.9	1.4
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.0	1.4	0.6	0.7
Arm fat percentage (right)	0.7	2.6	4.5	2.1	-0.7	-1.7
Hip circumference	0.7	2.9	4.4	2.1	-0.9	-1.9
Falls in the last year	0.7	1.0	2.2	0.4	0.7	1.5
Hair/balding pattern: Pattern 3	0.7	1.0	2.5	-0.3	1.6	0.7
Hair/balding pattern: Pattern 4	0.7	1.7	3.0	1.2	-1.7	-0.8
Forced vital capacity (FVC), Best measure	0.7	2.5	4.2	-1.1	2.0	1.4
Worry too long after embarrassment	0.7	1.3	3.6	1.9	0.4	0.1
Health satisfaction	0.7	0.9	1.4	0.6	-1.2	-1.0
Eye problems/disorders: None of the above	0.7	0.8	2.1	0.5	1.5	-0.1
Medication: Omeprazole	0.7	0.9	1.1	1.0	-1.0	0.8
Whole body fat mass	0.7	2.8	4.3	2.1	-1.1	-1.7
Leg fat mass (right)	0.7	2.7	4.2	1.7	-1.0	-2.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.0	-0.1	0.5	-1.4
Qualifications: nursing, teaching	0.7	1.1	1.6	-1.2	1.3	0.5
Mineral and other dietary supplements	0.7	0.9	2.7	1.6	0.1	0.3
Arm fat mass (left)	0.7	2.8	4.6	1.7	-0.9	-2.1
Medication: Atorvastatin	0.7	0.8	2.2	-0.1	0.6	1.5
Leg fat percentage (left)	0.7	2.7	5.0	2.2	-1.0	-1.5
Unable to work because of sickness or disability	0.7	0.9	2.8	0.1	-0.2	1.7
Major Depression (MDD)	0.6	0.7	1.2	-1.1	-0.5	0.8
Mean Putamen Volume	0.6	0.6	1.3	-0.1	1.1	0.8
Neuroticism (2016)	0.6	0.9	2.5	1.6	0.5	0.0
Respiratory disease	0.6	1.2	2.8	-0.8	0.5	1.7
Angina	0.6	0.8	1.2	0.4	-1.0	1.1
Maternal smoking around birth	0.6	0.9	2.2	-1.5	0.1	0.7
Bilateral oophorectomy (both ovaries removed)	0.6	0.6	1.5	-0.4	-0.5	-1.2
Impedance of leg (left)	0.6	3.0	3.3	1.5	-1.8	1.8
Exposure to tobacco smoke at home	0.6	0.6	1.0	0.9	-1.0	0.3
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.2	1.5	-0.0	-0.4
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.2	-1.1	-0.8	0.4
Medication for pain relief, constipation, heartburn	0.6	1.0	1.8	0.5	1.3	-1.0
Commuting to job workplace: Walk	0.6	0.6	1.1	-0.7	1.0	0.5
Back pain experienced in last month	0.6	0.9	2.6	-0.3	-0.3	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.2	-0.9	1.5	-1.0
Wears glasses or contact lenses	0.6	0.7	1.4	-1.2	0.9	-0.1
Hearing aid user	0.6	0.7	1.6	-1.3	-0.7	-0.1
High cholesterol (Self-reported)	0.6	1.0	3.0	-0.2	-0.1	1.7
Alcohol drinker status: Never	0.6	0.7	1.9	-0.1	-0.6	-1.4
Average weekly beer plus cider intake	0.6	0.9	2.7	1.6	0.1	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.1	0.3	-1.0	1.0
Basal cell carcinoma (self-reported)	0.6	0.7	1.7	-0.7	-1.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.1	0.7	-0.9	-1.1
Leg fat mass (left)	0.6	2.5	4.0	1.6	-0.9	-2.0
Alzheimer’s Disease (including proxy)	0.5	0.7	1.3	-1.1	0.2	0.8
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.4	0.4	0.3	1.8
Systolic Blood Pressure	0.5	2.7	3.4	1.8	1.9	1.2
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.1	-0.1	1.4	0.0
Medication: Metformin	0.5	0.7	1.4	0.8	-1.2	0.2
Impedance of leg (right)	0.5	2.6	4.5	1.3	-2.1	1.2
Hand grip strength (right)	0.5	1.4	2.0	-0.8	1.3	-1.4
Fed-up feelings	0.5	0.9	1.2	-0.7	1.0	1.1
Age when periods started (menarche)	0.5	1.1	1.9	-1.4	-0.8	0.9
Had menopause	0.5	0.7	1.3	-0.9	-0.0	1.1
Heart attack	0.5	0.6	0.9	0.4	-0.9	-0.9
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	3.3	-1.2	1.8	0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.9	1.7	0.2	0.3
Illnesses of mother	0.5	0.6	0.8	-0.9	0.4	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	4.5	-0.5	2.1	0.7
Arm fat mass (right)	0.5	2.2	3.7	1.4	-0.9	-1.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.8	-0.9	0.8	-0.5
Number of children fathered	0.5	0.5	1.1	0.6	0.3	1.1
Overall health rating	0.5	1.0	1.3	1.0	-0.9	-1.2
Chest pain or discomfort	0.5	0.7	1.7	-0.6	0.1	1.3
Illnesses of siblings: Diabetes	0.5	0.6	1.2	0.7	-1.1	-0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.2	1.1	-0.7	0.2
Diabetes diagnosed by doctor	0.5	0.8	1.5	-0.2	-1.2	1.0
Medication: Blood pressure	0.5	0.9	1.4	1.2	-1.0	0.6
Medication: Bendroflumethiazide	0.5	0.7	1.1	1.1	-0.2	0.9
Illnesses of father: High blood pressure	0.5	0.7	1.4	-0.8	1.2	0.1
Bipolar Disorder or Schizophrenia	0.4	1.0	1.9	-1.4	0.5	0.9
Neuroticism (Nagel 2018)	0.4	0.9	1.5	0.8	0.7	1.2
Crohns Disease (2017)	0.4	0.8	1.5	0.0	1.0	1.2
Coronary Artery Disease (CAD)	0.4	0.5	0.9	-0.4	0.6	0.9
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	0.9	-1.2	0.1
Sensitivity / hurt feelings	0.4	0.7	1.3	0.7	1.2	0.5
Diabetes (mother)	0.4	0.5	1.3	1.2	0.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.1	0.7	0.5	-1.0
Stomach or abdominal pain in last month	0.4	0.6	0.9	0.4	-1.0	0.8
Body mass index (BMI)	0.4	1.6	4.4	0.6	0.1	-2.1
Medication: Simvastatin	0.4	0.6	1.4	1.2	0.3	-0.6
Weight	0.4	1.7	4.4	0.8	-0.5	-2.1
Blood clot in the leg (DVT)	0.4	0.5	1.4	-0.2	0.4	1.2
Neck or shoulder pain in last month	0.4	0.6	1.2	-1.1	0.8	-0.0
Medication: Seretide 50 evohaler	0.4	0.5	0.7	-0.7	0.8	0.4
Number of full sisters	0.4	0.5	1.1	-0.3	-1.0	0.5
Suffer from ‘nerves’	0.4	0.6	1.3	0.7	1.2	-0.1
Family relationship satisfaction	0.4	0.5	0.9	0.7	-1.0	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.9	0.6	-0.6	-0.9
Average weekly red wine intake	0.4	0.6	1.0	-0.5	0.8	1.0
Mood swings	0.4	0.7	1.6	0.5	1.3	0.6
Eye problems/disorders: Cataract	0.4	0.5	0.9	-0.1	0.7	0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.4	0.8	0.2	-1.2
Eye problems/disorders: Glaucoma	0.4	0.5	0.8	-0.8	-0.9	0.4
Age started oral contraceptive pill	0.4	0.5	0.7	-0.8	0.9	-0.5
Cholesterol lowering medication	0.4	0.6	1.0	0.8	-0.1	1.0
Bipolar Disorder (2018)	0.3	0.5	0.9	0.4	1.0	0.7
Depressed Affect (Nagel 2018)	0.3	0.5	0.7	0.8	0.8	0.5
Prostate Cancer	0.3	0.4	0.6	-0.3	0.8	0.7
Fasting Glucose	0.3	0.4	0.9	1.0	0.4	-0.3
HDL Cholesterol	0.3	0.5	1.0	-0.1	-0.6	1.0
LDL Cholesterol	0.3	0.5	0.6	0.5	-0.8	0.8
Hypothyroidism (self reported)	0.3	0.6	1.0	0.5	1.0	0.7
Ever used hormone-replacement therapy (HRT)	0.3	0.3	1.0	1.0	0.0	0.1
Systolic blood pressure, automated reading	0.3	1.0	1.4	0.3	1.2	1.2
Pack years adult smoking proportion	0.3	0.4	0.9	0.1	-0.9	-0.5
Leg fat-free mass (left)	0.3	1.6	4.8	0.2	-0.1	-2.2
Average weekly fortified wine intake	0.3	0.3	0.8	-0.0	0.9	-0.4
Qualifications: CSEs or equivalent	0.3	0.4	0.5	-0.7	0.6	0.7
Hayfever, allergic rhinitis or eczema	0.3	0.8	1.2	1.1	-0.4	-0.9
Medication: Levothyroxine sodium	0.3	0.6	1.0	0.8	1.0	0.2
Leg predicted mass (left)	0.3	1.5	4.5	0.2	-0.1	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.1	1.1	-0.2	0.9
Neuroticism score	0.3	0.7	0.9	0.9	0.8	0.7
Happiness	0.3	0.4	0.7	0.8	-0.6	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.4	-0.6	-0.7	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.9	-1.0	-0.2	-0.4
High blood pressure (siblings)	0.3	0.5	0.9	-0.5	-0.9	-0.6
Number of full brothers	0.3	0.3	1.0	0.1	-0.0	1.0
Illnesses of father: Heart disease	0.3	0.4	0.5	-0.6	0.6	0.7
Ever had bowel cancer screening	0.3	0.4	0.6	0.3	-0.6	-0.8
Mother’s age at death	0.3	0.4	0.7	0.2	-0.8	0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.6	0.5	0.8	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	-0.9	0.7	-0.2
Medication: Lisinopril	0.3	0.4	0.9	-0.9	-0.3	-0.6
Irritability	0.3	0.4	1.2	-0.4	0.0	1.1
Ever depressed for a whole week	0.3	0.4	0.8	-0.6	0.2	-0.9
Commuting to job workplace: Cycle	0.3	0.4	1.0	1.0	-0.1	0.4
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.8	-0.6	0.4	-1.3
Pack years of smoking	0.3	0.5	1.3	0.1	-1.2	-0.2
Bipolar Disorder (2011)	0.2	0.2	0.3	0.5	0.6	0.2
Body Mass Index (BMI) (2010)	0.2	0.3	0.6	-0.4	-0.8	-0.1
Primary Biliary Cirrhosis	0.2	0.4	0.6	0.8	0.4	-0.6
Blood Eosinophil Count	0.2	1.4	3.3	0.7	1.8	0.4
Blood Red Count	0.2	1.9	3.0	1.7	-0.0	-1.7
BMI	0.2	1.0	2.3	-0.0	0.9	-1.5
Cardiovascular Disease	0.2	0.5	0.7	0.8	0.5	0.9
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.8	0.2	0.3
Supplements: Zinc	0.2	0.2	0.6	-0.8	0.1	-0.3
Current tobacco smoking	0.2	0.3	0.6	-0.8	-0.2	-0.6
Alcohol usually taken with meals	0.2	0.3	0.7	-0.6	0.8	-0.2
Nervous feelings	0.2	0.5	0.7	0.8	0.8	0.3
Diabetes (self-reported)	0.2	0.4	1.1	-0.0	-1.0	0.2
Medication: Ramipril	0.2	0.2	0.5	0.2	-0.7	0.2
Trunk fat-free mass	0.2	1.3	2.0	-1.4	0.2	-1.4
Lung cancer (father)	0.2	0.3	0.5	-0.5	-0.7	0.4
Trunk predicted mass	0.2	1.2	1.8	-1.3	0.2	-1.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	0.1	-0.1	-0.9
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.9	-0.3	0.9	0.1
Arm fat-free mass (right)	0.2	1.1	2.8	-0.7	0.1	-1.7
Comparative body size at age 10	0.2	0.6	1.1	-1.0	0.9	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.5	0.8	0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	0.7	-0.5	-0.3
Medication: Blood pressure	0.2	0.4	1.1	-0.3	-0.3	1.0
Migraine (self-reported)	0.2	0.3	0.5	-0.1	0.7	-0.6
Arm predicted mass (right)	0.2	1.0	2.2	-0.8	0.2	-1.5
Comparative height size at age 10	0.2	1.2	2.0	0.9	-1.4	0.9
Whole body fat-free mass	0.2	1.2	3.1	-0.7	0.2	-1.8
Leg fat-free mass (right)	0.2	1.1	3.2	0.1	0.1	-1.8
Osteoporosis (self-reported)	0.2	0.2	0.3	0.5	-0.6	0.3
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.1	0.6	-0.6
Whole body water mass	0.2	1.2	3.0	-0.6	0.2	-1.7
Leg predicted mass (right)	0.2	1.0	2.9	0.2	0.1	-1.7
Guilty feelings	0.2	0.2	0.6	0.8	0.4	-0.0
Basal metabolic rate	0.2	1.2	3.6	-0.3	-0.0	-1.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	0.1	0.4	0.7
Arm predicted mass (left)	0.2	0.8	1.9	-0.7	0.3	-1.4
Worry (Nagel 2018)	0.1	0.1	0.3	-0.3	0.1	0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.2	-0.5	0.0	0.2
Breast Cancer	0.1	0.2	0.6	-0.8	-0.1	0.1
Schizophrenia (2014)	0.1	0.3	0.7	-0.9	-0.1	0.5
Blood White Count	0.1	1.0	1.6	1.3	0.5	-1.0
Heel T-Score	0.1	0.6	1.7	1.3	-0.1	0.2
Height	0.1	1.0	1.2	1.1	-1.0	0.9
Smoking Status	0.1	0.2	0.4	-0.4	-0.1	-0.7
Allergy or Eczema	0.1	0.4	0.6	0.8	0.7	-0.3
Lung FEV1/FVC ratio	0.1	0.4	0.7	0.6	0.9	-0.4
Neuroticism	0.1	0.3	0.8	0.9	-0.2	0.3
Hair Pigment	0.1	1.6	3.7	-0.9	-0.4	1.9
Tanning	0.1	0.7	1.3	-1.1	-0.6	-0.6
Relative age voice broke	0.1	0.1	0.2	-0.4	0.2	-0.4
High blood pressure	0.1	0.4	0.9	0.2	-0.5	0.9
Sitting height	0.1	0.6	1.5	0.6	-1.2	0.2
Past tobacco smoking	0.1	0.2	0.7	-0.1	-0.8	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.6	0.0	-0.3
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	0.1	0.5	-0.0
Allergy	0.1	0.3	0.8	-0.2	-0.1	-0.9
Illnesses of siblings	0.1	0.2	0.5	-0.2	0.7	0.2
Worrier / anxious feelings	0.1	0.3	0.7	-0.8	-0.3	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.1	0.6	-0.5
Standing height	0.1	1.0	2.8	0.2	-1.7	0.0
Tense / ‘highly strung’	0.1	0.1	0.3	-0.5	0.0	-0.4
Age at first live birth	0.1	0.1	0.2	0.3	-0.4	-0.3
Qualifications: College or University degree	0.1	0.4	0.7	-0.6	0.8	0.3
Alcohol intake frequency.	0.1	0.3	0.6	0.4	0.3	-0.8
Age at last live birth	0.1	0.1	0.2	0.0	0.3	0.5
Hypertension (Self-reported)	0.1	0.2	0.5	0.2	0.2	0.7
Smoking status: Previous	0.1	0.1	0.3	0.2	0.5	-0.1
Smoking status: Current	0.1	0.2	0.4	-0.6	-0.1	-0.4
Arm fat-free mass (left)	0.1	0.7	1.5	-0.7	0.3	-1.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.5	0.0	-0.3
Diastolic blood pressure, automated reading	0.1	0.4	0.8	0.5	0.4	0.9
Alcohol drinker status: Previous	0.1	0.2	0.3	0.1	0.4	0.6
Depression (Nagel 2018)	0.0	0.1	0.1	0.4	0.0	-0.3
Blood Platelet Count	0.0	0.5	1.0	0.5	-0.6	1.0
Townsend deprivation index at recruitment	0.0	0.1	0.2	0.4	0.1	0.2
Number of incorrect matches in round	0.0	0.0	0.0	0.2	0.2	0.1
Number of live births	0.0	0.1	0.2	0.0	0.2	0.4
Medication: Cholesterol lowering	0.0	0.1	0.1	0.4	-0.1	-0.1
Birth weight of first child	0.0	0.1	0.1	-0.3	-0.3	-0.1
Medication: Paracetamol	0.0	0.0	0.1	0.0	0.3	0.3
Medication: Paracetamol	0.0	0.0	0.1	0.2	-0.1	-0.3

Hub : Genes

CCDC141

Models

Trait associations