Hub : Genes

CCDC142

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.061 0.030 0.0062 -0.002 0.002 0.006 0.004 -0.002 0.69 0.16 0.058 0.087 0.89
2 GTEx Cells Transformed fibroblasts 0.070 0.031 0.0065 -0.004 NA -0.002 NA -0.004 0.98 NA 0.460 NA 0.89

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.5 0.7 0.8 0.8 -0.9
Bipolar Disorder or Schizophrenia 0.5 1.3 2.4 0.4 -1.5
Depressed Affect (Nagel 2018) 0.2 0.4 0.7 -0.8 -0.3
Depression (Nagel 2018) 0.1 0.1 0.1 0.4 -0.3
Intelligence (Savage-Jansen 2018) 0.5 1.5 2.4 -0.8 1.5
Neuroticism (Nagel 2018) 0.5 1.1 1.7 -1.3 0.6
Schizophrenia (2018) 0.4 0.8 1.6 -0.2 -1.3
Schizophrenia vs Biploar Disorder 0.7 1.0 1.9 -1.4 -0.0
Worry (Nagel 2018) 0.3 0.5 0.7 0.6 0.8
Alzheimer’s Disease (in mother) 1.3 1.5 2.1 -1.0 1.5
Alzheimer’s Disease (in father) 2.9 3.1 6.0 -0.4 2.5
Alzheimer’s Disease (including proxy) 3.4 4.9 8.4 -1.2 2.9
Crohns Disease (2017) 0.2 0.4 0.6 -0.8 0.4
Irritable Bowel Disease (IBD) 0.3 0.6 1.2 -1.1 0.2
Ulcerative Colitis (UC) 0.0 0.0 0.1 -0.3 -0.1
Major Depression (MDD) 0.4 0.4 0.9 -0.2 0.9
Reaction Time 0.4 0.8 1.1 -0.8 -1.1
Verbal and Numeric Reasoning (VNR) 0.8 1.8 3.5 -0.4 1.9
Breast Cancer 0.8 1.9 3.0 1.7 0.9
Ovarian Cancer 0.0 0.0 0.0 -0.0 -0.1
Prostate Cancer 0.0 0.1 0.1 0.2 -0.3
Age at First Birth 1.9 2.7 5.1 -0.6 2.2
Bipolar Disorder (2011) 2.0 2.0 2.9 -1.1 -1.7
Body Mass Index (BMI) (2010) 0.1 0.1 0.1 0.4 0.2
Coronary Artery Disease (CAD) 1.0 1.2 1.6 -0.9 1.2
Crohns Disease (2012) 0.8 1.4 1.7 -1.0 -1.3
Mean Putamen Volume 1.3 1.5 2.9 -1.7 -0.3
Fasting Glucose 0.7 0.8 1.6 1.3 0.2
HbA1C 1.7 1.9 3.7 0.4 1.9
HDL Cholesterol 0.2 0.3 0.5 -0.7 0.2
LDL Cholesterol 0.4 0.7 0.8 0.9 -0.8
Lupus 1.1 1.6 2.8 -0.7 -1.7
Neuroticism (2016) 0.4 0.6 0.9 -1.0 -0.5
Primary Biliary Cirrhosis 0.7 0.9 1.4 -0.7 -1.2
Rheumatoid Arthritis 0.4 0.6 0.7 -0.7 0.8
Schizophrenia (2014) 1.1 2.3 4.3 -0.6 -2.1
Triglycerides 2.3 3.8 7.7 2.8 0.1
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.3 -0.4 -0.6
Ulcerative Colitis 0.2 0.3 0.6 -0.3 -0.8
Blood Eosinophil Count 0.6 5.0 9.9 -0.2 -3.1
Blood Platelet Count 4.2 48.6 55.2 7.4 -6.5
Blood Red Count 0.3 2.7 5.3 2.3 0.5
Blood White Count 0.5 3.8 7.4 2.7 0.4
Heel T-Score 0.5 3.9 4.4 -1.8 2.1
BMI 0.0 0.0 0.0 0.1 -0.2
Height 1.2 22.7 35.3 -3.2 -5.9
Waist Hip Ratio (WHR) 0.3 1.5 2.7 1.6 -0.5
Systolic Blood Pressure 0.8 3.8 7.1 0.7 2.7
Smoking Status 0.6 1.4 2.3 -1.5 -0.7
Allergy or Eczema 1.4 3.8 5.9 1.3 -2.4
Cardiovascular Disease 0.9 3.0 5.8 2.4 0.5
Hypothyroidism (self reported) 0.1 0.1 0.3 -0.5 -0.1
Respiratory disease 0.8 1.9 3.5 -0.5 -1.9
Type 2 Diabetes (T2D) (2018) 0.3 0.6 0.7 0.9 -0.7
Lung FEV1/FVC ratio 0.1 0.6 0.9 0.9 0.6
Lung FVC 0.4 2.3 3.4 -1.9 1.0
Neuroticism 0.2 0.6 1.0 -0.4 1.0
Chronotype (morning person) 2.1 4.8 9.4 3.1 -0.5
Hair Pigment 0.0 1.0 1.3 1.1 0.8
Tanning 0.1 1.6 2.6 -0.7 -1.6
Hand grip strength (left) 0.1 0.4 0.6 0.8 0.4
Number of treatments/medications taken 0.7 1.2 1.4 -1.2 1.0
Average weekly spirits intake 1.2 1.5 2.9 -0.5 -1.7
Sensitivity / hurt feelings 0.4 0.7 1.3 -1.1 0.2
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.7 0.8 0.0
Hearing difficulty/problems: Yes 1.0 1.5 2.8 -1.7 -0.5
Relative age of first facial hair 0.6 1.3 2.5 -0.1 -1.6
Other serious medical condition/disability diagnosed by doctor 0.4 0.6 1.1 -1.0 -0.1
Ever used hormone-replacement therapy (HRT) 1.0 1.2 1.6 -1.3 -0.9
Ever had hysterectomy (womb removed) 1.0 1.1 2.1 -1.4 0.5
Systolic blood pressure, automated reading 0.5 1.4 2.6 -0.4 1.6
Eye problems/disorders: Diabetes related eye disease 1.1 1.2 2.0 1.4 0.7
Angina 0.9 1.2 2.4 0.2 1.5
Medication for hormone replacement therapy 3.9 4.3 8.6 -2.9 0.2
Vitamin and mineral supplements 1.2 1.6 2.8 1.7 -0.6
Supplements: Zinc 2.1 2.2 2.9 -1.2 1.7
Medication: Co-codamol 0.3 0.4 0.8 0.1 -0.9
Medication: Metformin 0.3 0.4 0.7 0.4 -0.8
Diabetes (father) 1.2 1.5 1.6 1.3 1.2
Diabetes (mother) 0.1 0.2 0.4 -0.6 -0.1
Severe depression (siblings) 0.8 0.9 1.0 0.9 -1.0
Pack years adult smoking proportion 0.2 0.3 0.3 0.5 0.6
Impedance of leg (right) 0.3 1.3 1.5 1.1 1.2
Leg fat-free mass (left) 1.0 5.3 8.8 -1.4 -3.0
Trunk fat percentage 0.3 1.4 2.0 -0.9 1.4
Hand grip strength (right) 0.1 0.2 0.5 -0.1 0.7
Townsend deprivation index at recruitment 0.3 0.5 0.9 -0.3 -0.9
Current tobacco smoking 0.7 1.2 1.7 -1.3 -0.8
Average weekly fortified wine intake 0.1 0.2 0.2 0.4 0.3
Maternal smoking around birth 0.8 1.1 2.0 -1.4 -0.4
Fed-up feelings 0.3 0.5 0.9 -0.9 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.9 1.2 -1.1 -0.7
Relative age voice broke 0.1 0.1 0.2 -0.1 0.4
Taking other prescription medications 1.6 2.4 4.8 -2.2 -0.2
Age when periods started (menarche) 0.0 0.1 0.2 0.4 0.1
Bilateral oophorectomy (both ovaries removed) 1.5 1.7 2.1 -1.5 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 1.7 -0.3 1.3
Tinnitus: Yes, but not now, but have in the past 1.5 1.6 1.7 -1.2 1.3
Qualifications: CSEs or equivalent 0.5 0.7 1.2 -1.1 0.4
Serious illness, injury or assault to yourself 0.6 0.7 0.9 -0.9 -0.8
High blood pressure 0.1 0.3 0.5 0.3 0.7
Hayfever, allergic rhinitis or eczema 2.5 5.5 9.2 1.4 -3.0
Multivitamins +/- minerals 0.5 0.7 1.4 -1.2 -0.0
Stomach or abdominal pain in last month 0.5 0.6 1.1 -1.1 0.3
Supplements: Glucosamine 0.0 0.0 0.0 -0.2 0.0
Diverticular disease/diverticulitis (self-reported) 1.5 1.8 3.5 1.9 0.1
Medication: Atenolol 3.2 4.0 7.2 -0.9 2.7
Medication: Levothyroxine sodium 1.0 1.8 3.4 0.3 -1.9
Sitting height 0.9 6.5 10.9 -1.4 -3.3
Chronic bronchitis/emphysema (father) 0.6 0.7 0.9 0.6 -0.9
High blood pressure (mother) 0.5 0.7 1.5 1.2 -0.1
Body mass index (BMI) 0.0 0.1 0.2 -0.4 -0.0
Impedance of leg (left) 0.3 1.5 1.8 1.4 1.1
Leg predicted mass (left) 1.0 5.3 8.9 -1.3 -3.0
Trunk fat mass 0.1 0.6 1.1 -1.1 0.3
Waist circumference 0.2 0.6 1.1 -0.1 -1.1
Number of incorrect matches in round 0.0 0.0 0.1 -0.1 0.3
Past tobacco smoking 2.1 3.9 6.2 2.5 1.2
Alcohol usually taken with meals 0.6 1.0 1.8 -0.5 1.3
Nervous feelings 0.1 0.2 0.2 0.5 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 0.7 -0.1 -0.8
Hearing difficulty/problems with background noise 1.2 2.0 3.8 -1.9 0.4
Hair/balding pattern: Pattern 2 2.6 3.4 6.7 0.2 2.6
Had menopause 0.5 0.7 0.9 1.0 -0.7
Had other major operations 1.4 1.7 2.3 -1.5 -1.0
Forced vital capacity (FVC) 0.1 0.2 0.4 -0.1 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 2.5 -0.5 1.6
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 0.5 -0.1 0.7
Qualifications: None of the above 0.2 0.3 0.6 -0.8 -0.3
Financial difficulties in last 2 years 1.0 1.3 1.7 0.9 -1.3
Mouth/teeth dental problems 2.3 3.5 6.1 2.5 1.0
Heart attack 0.6 0.7 1.2 0.5 -1.1
Allergy 2.4 5.4 9.5 -1.2 3.1
Pain all over the body in last month 0.4 0.4 0.8 -0.9 -0.2
Diabetes (self-reported) 0.1 0.1 0.1 0.3 -0.3
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 0.9 0.9 -0.5
Medication: Ramipril 0.1 0.2 0.2 0.5 -0.3
Medication: Simvastatin 1.0 1.4 2.8 1.7 0.1
Fluid intelligence score 0.3 0.7 1.4 -0.2 1.2
Illnesses of siblings 1.1 1.6 2.2 1.5 -1.0
Neuroticism score 0.2 0.5 0.9 -1.0 0.1
Weight 0.4 2.1 3.1 -1.0 -1.8
Impedance of arm (right) 0.2 1.1 1.8 0.5 1.4
Arm fat percentage (right) 0.4 1.5 2.2 -1.0 1.5
Trunk fat-free mass 1.6 9.2 17.4 -1.0 -4.2
Hip circumference 0.1 0.4 0.6 -0.3 -0.8
Time employed in main current job 1.8 2.1 4.0 -2.0 0.4
Alcohol intake versus 10 years previously 0.2 0.4 0.7 -0.9 -0.1
Father’s age at death 2.2 3.0 5.8 -2.4 0.5
Worrier / anxious feelings 0.0 0.0 0.0 0.0 -0.2
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 1.3 -1.2 -0.5
Falls in the last year 1.5 2.1 4.0 -0.5 -2.0
Hair/balding pattern: Pattern 3 2.1 3.2 4.7 -2.2 1.3
Number of live births 1.0 1.4 2.8 0.2 -1.7
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 0.4 0.7 -0.2
Pulse rate 1.4 2.4 4.8 2.2 -0.3
Happiness 0.3 0.3 0.6 0.2 -0.8
Noisy workplace 0.4 0.5 0.7 -0.5 -0.8
Qualifications: A levels/AS levels or equivalent 0.4 0.9 1.4 0.6 1.2
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 1.3 1.2 0.7
Mouth/teeth dental problems: Dentures 2.1 3.6 6.4 -2.5 0.9
Asthma 0.5 0.9 1.2 -0.8 -1.1
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.2 -0.4 0.3
Medication: Cholesterol lowering 1.3 2.1 2.4 1.6 1.3
Depression (self-reported) 0.9 1.0 1.0 1.0 -1.0
Medication: Lansoprazole 1.6 1.8 3.3 -0.6 1.8
Prospective memory result 0.9 1.1 2.1 -1.5 0.3
Lung cancer (father) 0.8 0.9 1.2 -1.1 -0.8
Illnesses of mother 0.7 0.9 1.7 -1.3 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.5 0.8 0.9 -0.4
Pulse wave Arterial Stiffness index 0.2 0.3 0.4 0.4 -0.6
Impedance of arm (left) 0.5 2.1 3.9 0.6 2.0
Arm fat mass (right) 0.1 0.3 0.6 -0.8 0.3
Trunk predicted mass 1.5 8.7 16.4 -0.9 -4.0
Standing height 1.0 9.6 17.3 -1.3 -4.2
Length of working week for main job 0.9 1.0 1.3 1.1 0.9
Exposure to tobacco smoke at home 0.7 0.8 0.9 1.0 0.8
Breastfed as a baby 0.6 0.8 1.1 -0.6 1.0
Tense / ‘highly strung’ 1.0 1.6 3.2 -1.8 -0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 0.9 0.9 -0.2
Hair/balding pattern: Pattern 4 1.0 2.4 2.9 1.7 -1.4
Birth weight of first child 0.4 0.7 0.7 -0.8 -0.8
Peak expiratory flow (PEF) 0.7 1.6 2.4 1.6 -0.9
Pulse wave reflection index 0.3 0.3 0.5 -0.7 0.4
Ever highly irritable/argumentative for 2 days 0.4 0.5 0.8 0.9 0.3
Loud music exposure frequency 1.2 1.3 2.6 1.6 -0.1
Qualifications: O levels/GCSEs or equivalent 0.1 0.2 0.2 0.4 0.5
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 0.9 -0.5 -1.0
Blood clot in the leg (DVT) 0.0 0.0 0.0 -0.2 -0.1
Medication: Paracetamol 0.5 0.9 1.8 -0.1 -1.3
Headache pain in last month 1.2 2.0 3.8 -2.0 0.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 0.7 -0.4 -0.8
Glaucoma (self-reported) 0.3 0.4 0.6 0.4 0.8
Gout (self-reported) 0.5 0.6 0.6 0.8 -0.8
Hypothyroidism/myxoedema (self-reported) 0.6 1.1 2.1 -0.3 -1.4
Medication: Amlodipine 0.2 0.3 0.6 -0.1 0.8
Medication: Ventolin 100micrograms inhaler 1.1 1.5 2.1 -1.5 -0.9
Birth weight 0.3 0.6 1.1 -1.1 0.3
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.0 -1.0 0.3
High blood pressure (siblings) 2.2 3.2 5.2 -1.1 2.3
Forced vital capacity (FVC), Best measure 0.2 0.6 1.3 0.2 -1.1
Body fat percentage 0.4 1.5 2.3 -0.8 1.5
Leg fat percentage (right) 0.3 1.1 2.0 -0.5 1.4
Arm fat-free mass (right) 1.0 5.0 8.1 -1.3 -2.9
Exposure to tobacco smoke outside home 0.8 1.0 2.0 -1.4 0.2
Comparative body size at age 10 0.5 1.3 2.6 1.6 -0.0
Number of full brothers 0.0 0.0 0.0 0.0 -0.0
Worry too long after embarrassment 2.3 3.8 5.6 -2.4 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.2 -0.6 1.5
Wheeze or whistling in the chest in last year 1.8 3.1 4.6 -1.3 -2.1
Number of children fathered 1.9 2.2 2.8 1.7 -1.3
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 1.4 -0.5 1.2
Age at first live birth 1.2 2.1 4.2 -0.1 2.0
Pulse wave peak to peak time 0.2 0.2 0.4 -0.3 0.6
Health satisfaction 2.5 3.3 4.9 -1.3 -2.2
Shortness of breath walking on level ground 1.2 1.5 2.1 0.9 -1.4
Qualifications: College or University degree 0.2 0.5 1.1 -0.1 1.0
Eye problems/disorders: None of the above 1.1 1.2 1.5 -1.0 -1.2
Mouth/teeth dental problems: Loose teeth 0.7 0.8 1.6 0.2 -1.3
Emphysema/chronic bronchitis 0.1 0.1 0.1 -0.0 0.4
Medication for pain relief, constipation, heartburn 0.8 1.3 2.0 1.4 -0.8
Neck or shoulder pain in last month 1.7 2.5 3.3 -1.8 -1.3
Medication: Blood pressure 0.3 0.6 1.1 -0.1 1.1
Angina (self-reported) 0.7 1.0 1.9 0.1 1.4
Migraine (self-reported) 0.6 0.7 1.2 -1.1 0.5
Medication: Ibuprofen 0.2 0.3 0.6 -0.7 0.1
Medication: Allopurinol 0.4 0.6 1.0 1.0 -0.3
Medication: Omeprazole 3.6 4.3 5.4 -2.3 1.8
Medication: Seretide 50 evohaler 1.5 1.7 2.9 -0.7 -1.7
Mean time to correctly identify matches 1.1 2.1 3.6 -0.8 -1.9
Heart disease (mother) 0.9 1.1 1.5 -0.9 -1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.2 5.0 6.8 2.6 -1.8
Whole body fat mass 0.1 0.5 1.0 -1.0 0.3
Leg fat mass (right) 0.1 0.3 0.6 -0.8 0.1
Arm predicted mass (right) 0.9 4.7 7.9 -1.2 -2.8
Pulse rate, automated reading 1.2 3.9 6.3 2.5 -1.2
Alcohol intake frequency. 0.7 1.7 3.5 1.9 -0.2
Comparative height size at age 10 1.0 5.5 10.8 -0.5 -3.3
Number of full sisters 0.5 0.7 1.2 -0.3 -1.1
Suffer from ‘nerves’ 1.6 2.5 4.0 1.0 2.0
Overall health rating 1.8 4.0 5.7 -2.4 -1.5
Chest pain or discomfort 0.2 0.2 0.4 -0.6 0.2
Had major operations 1.6 1.9 2.3 1.2 -1.5
Age at last live birth 0.8 1.2 1.3 -1.2 1.1
Family relationship satisfaction 1.7 2.1 3.2 -1.8 1.0
Leg pain on walking 1.8 2.3 4.3 -0.6 -2.1
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.6 3.2 1.8 -0.3
Commuting to job workplace: Car/motor vehicle 0.8 0.9 1.6 1.2 -0.5
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.1 -0.1 1.1
Medication: Aspirin 0.1 0.1 0.3 0.0 0.5
Supplements: Vitamin C 3.1 3.6 4.5 -1.7 2.1
Knee pain experienced in last month 0.7 1.1 1.2 1.0 -1.1
Hypertension (Self-reported) 0.1 0.4 0.7 0.3 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 1.5 -1.2 1.0
Illnesses of father: Heart disease 2.5 3.5 6.4 0.8 2.5
Illnesses of siblings: Diabetes 0.7 0.9 1.1 0.8 -1.0
Smoking status: Previous 1.3 2.0 2.8 -1.7 -1.1
Forced expiratory volume in 1-second (FEV1), predicted 1.8 3.7 5.4 1.4 -2.3
Whole body fat-free mass 1.4 8.2 14.7 -1.3 -3.8
Leg fat-free mass (right) 1.1 6.1 10.4 -1.3 -3.2
Arm fat percentage (left) 0.6 2.4 3.9 -0.9 2.0
Average weekly red wine intake 0.9 1.4 2.1 -1.5 0.8
Handedness (chirality/laterality): Left-handed 0.3 0.3 0.6 -0.0 -0.8
Mood swings 0.1 0.1 0.1 -0.3 0.4
Loneliness, isolation 0.1 0.1 0.2 0.4 -0.1
Long-standing illness, disability or infirmity 0.2 0.3 0.5 0.0 0.7
Ever had bowel cancer screening 1.2 1.5 2.5 -0.7 -1.6
Diabetes diagnosed by doctor 0.3 0.4 0.7 0.5 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.0 0.0 0.0 -0.2 0.1
Friendships satisfaction 0.9 1.1 1.7 -1.3 0.7
Qualifications: nursing, teaching 0.7 1.1 1.4 0.8 1.2
Commuting to job workplace: Walk 0.8 0.9 0.9 -0.9 -1.0
Eye problems/disorders: Cataract 0.2 0.3 0.4 -0.3 0.7
Mouth/teeth dental problems: Mouth ulcers 1.9 3.0 5.3 0.8 -2.3
Medication for cholesterol 1.6 2.4 4.0 2.0 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 1.4 1.1 -1.2
Back pain experienced in last month 0.4 0.6 1.1 1.1 -0.4
Mineral and other dietary supplements 0.6 0.9 1.3 -1.1 0.6
Breast cancer (self-reported) 0.1 0.1 0.3 -0.5 0.1
Asthma (self-reported) 0.5 1.0 1.6 -0.7 -1.2
Osteoporosis (self-reported) 0.3 0.4 0.8 0.1 0.9
Osteoarthritis (self-reported) 0.4 0.6 0.9 -0.4 -1.0
Medication: Aspirin 0.6 0.8 1.5 0.3 1.2
Medication: Gliclazide 0.3 0.3 0.4 0.6 -0.6
Illnesses of father: None of the above (group 1) 3.8 4.7 9.0 -3.0 -0.6
Smoking status: Current 0.9 1.5 2.6 -1.6 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.4 5.1 7.3 2.7 1.7
Whole body water mass 1.3 7.3 13.0 -1.3 -3.6
Leg predicted mass (right) 1.1 5.9 10.3 -1.3 -3.2
Arm fat mass (left) 0.1 0.5 0.6 -0.8 0.7
Number of self-reported non-cancer illnesses 1.0 1.7 2.5 -1.0 -1.6
Average weekly champagne plus white wine intake 2.6 3.5 5.8 -1.1 2.4
Miserableness 1.4 2.4 2.6 -1.6 -1.5
Guilty feelings 0.6 0.9 1.5 -1.2 0.5
Wears glasses or contact lenses 3.9 4.5 5.6 1.9 -2.4
Ever taken oral contraceptive pill 2.0 2.2 4.3 0.3 -2.1
Hearing aid user 0.2 0.2 0.2 0.4 0.4
Mother’s age at death 0.7 0.9 1.4 1.2 -0.6
Financial situation satisfaction 1.3 1.7 1.9 -1.4 -1.2
Tinnitus: Yes, now most or all of the time 1.1 1.3 2.3 0.6 1.5
Commuting to job workplace: Public transport 2.0 2.4 4.2 -2.0 0.8
Eye problems/disorders: Glaucoma 0.3 0.3 0.5 0.4 0.7
Medication: Blood pressure 0.8 1.5 2.8 -0.3 1.7
Pain type(s) experienced in last month: Hip pain 1.2 1.6 3.1 1.8 -0.2
Supplements: Fish oil (including cod liver oil) 0.8 1.1 1.9 1.4 -0.4
High cholesterol (Self-reported) 0.1 0.1 0.1 0.4 -0.2
Medication: Bendroflumethiazide 0.5 0.7 1.4 0.0 1.2
Medication: Paracetamol 0.1 0.1 0.2 -0.2 -0.4
Medication: Lisinopril 0.5 0.6 1.0 -0.4 1.0
Medication: Atorvastatin 0.1 0.1 0.2 0.4 -0.2
Illnesses of father: High blood pressure 0.9 1.1 2.0 0.3 1.4
Alcohol drinker status: Never 0.9 1.0 2.1 1.4 -0.2
Ever smoked 2.0 3.4 6.6 -2.6 -0.5
Basal metabolic rate 1.1 6.1 10.8 -1.2 -3.3
Leg fat percentage (left) 0.2 0.5 1.0 -0.3 1.0
Arm fat-free mass (left) 1.2 5.9 11.1 -0.8 -3.3
Number of operations (self-reported) 2.0 3.0 3.4 -1.9 -1.6
Average weekly beer plus cider intake 0.0 0.0 0.0 0.1 0.1
Irritability 3.0 5.1 5.7 -2.4 2.1
Risk taking 0.5 0.7 0.8 -0.9 -0.8
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.2 -0.2 -0.5
Fractured/broken bones in last 5 years 2.3 3.0 5.8 2.4 0.4
Age started oral contraceptive pill 1.3 1.6 3.2 -1.8 0.3
Diastolic blood pressure, automated reading 0.6 1.8 3.4 0.4 1.8
Ever depressed for a whole week 0.1 0.1 0.3 0.5 -0.1
Unable to work because of sickness or disability 1.6 2.0 2.1 1.4 -1.4
Commuting to job workplace: Cycle 1.7 2.1 2.5 -1.3 1.6
Myopia 1.8 2.6 5.1 -2.2 -0.3
Vascular/heart problems diagnosed by doctor 0.1 0.3 0.4 -0.6 -0.4
Cholesterol lowering medication 0.4 0.7 1.3 0.1 -1.1
Medication: Omeprazole (e.g. Zanprol) 2.9 3.6 3.8 -1.8 1.9
Pain experienced in last month 1.2 1.9 3.2 0.8 1.8
Supplements: Calcium 0.4 0.4 0.9 -0.1 0.9
Basal cell carcinoma (self-reported) 0.5 0.6 1.1 -1.1 0.2
Heart attack/myocardial infarction (self-reported) 0.4 0.5 0.6 0.6 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.2 -0.4 0.0
Heart disease (siblings) 0.7 0.8 0.9 -1.0 0.8
Alcohol drinker status: Previous 0.1 0.1 0.2 -0.4 0.0
Pack years of smoking 0.4 0.5 1.0 0.3 1.0
Impedance of whole body 0.4 1.8 2.7 1.0 1.6
Leg fat mass (left) 0.1 0.3 0.6 -0.8 -0.2
Arm predicted mass (left) 1.2 6.2 11.2 -1.1 -3.4