Hub : Genes

CCDC146

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0230	1.2e-02	-0.001	0.001	-0.002	0.006	-0.001	4.8e-01	2.1e-01	8.7e-01	5.4e-02	4.6e-01
2	GTEx	Cells Transformed fibroblasts	0.1380	0.0590	7.6e-03	0.008	NA	0.000	NA	0.008	7.8e-02	NA	3.0e-01	NA	7.7e-02
3	GTEx	Nerve Tibial	0.2768	0.0886	8.5e-04	0.004	NA	0.019	NA	0.019	1.5e-01	NA	1.6e-02	NA	1.5e-02
4	GTEx	Spleen	0.3590	0.1090	3.0e-03	-0.012	NA	0.085	NA	0.000	9.3e-01	NA	3.3e-03	NA	3.1e-01
5	GTEx	Testis	0.2100	0.0830	2.9e-03	0.014	NA	0.014	NA	-0.002	7.5e-02	NA	7.4e-02	NA	3.9e-01
6	GTEx	Thyroid	0.1080	0.0430	1.8e-03	0.025	NA	0.014	NA	0.026	4.7e-03	NA	2.5e-02	NA	4.1e-03
7	NTR	Blood	0.0534	0.0138	1.6e-11	0.034	0.040	0.050	0.045	0.048	4.2e-11	6.1e-13	8.4e-16	3.3e-14	3.5e-15
8	YFS	Blood	0.4054	0.0451	0.0e+00	0.163	0.281	0.302	NA	0.287	4.4e-51	9.3e-93	1.3e-100	NA	4.1e-95
9	TCGA	Esophageal Carcinoma	0.2060	0.0970	4.7e-03	0.002	0.014	0.027	NA	-0.003	2.6e-01	1.2e-01	4.6e-02	NA	4.3e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.3	0.8	-0.4	0.0	0.0	-0.2	-0.8	0.9	-0.1	-0.4	-0.7
Bipolar Disorder or Schizophrenia	0.6	1.6	7.8	0.8	0.0	0.0	0.9	-0.9	2.8	1.1	0.4	-1.7
Depressed Affect (Nagel 2018)	1.1	2.3	8.8	-1.1	0.5	1.0	1.2	1.5	2.3	0.5	0.2	-3.0
Depression (Nagel 2018)	0.3	0.5	2.2	-1.5	0.7	0.2	-0.2	0.3	-0.2	-0.7	-0.8	-0.2
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.2	1.6	0.9	1.4	0.6	1.2	-0.7	2.0	1.4	0.9
Neuroticism (Nagel 2018)	1.4	3.3	9.1	-0.6	1.2	2.2	1.9	1.9	2.2	0.9	0.6	-3.0
Schizophrenia (2018)	0.9	1.9	8.2	1.3	0.0	0.0	1.8	-0.4	2.9	1.5	0.7	-1.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.7	0.2	0.0	0.0	-1.3	-0.3	0.3	-0.7	-0.0	0.6
Worry (Nagel 2018)	1.1	2.3	7.1	-1.1	1.0	1.9	1.6	0.9	2.1	-0.1	0.4	-2.7
Alzheimer’s Disease (in mother)	1.3	1.6	3.8	-1.6	0.4	1.0	-0.7	0.6	0.8	-1.5	-1.7	-1.9
Alzheimer’s Disease (in father)	0.4	0.4	1.2	0.6	0.3	0.4	-0.6	-1.0	0.7	1.1	0.4	0.5
Alzheimer’s Disease (including proxy)	0.6	0.9	1.7	-0.5	0.9	1.3	-0.7	0.7	1.3	-0.1	-0.8	-1.2
Crohns Disease (2017)	0.8	1.8	6.7	1.2	-1.1	0.2	0.2	-0.4	2.1	2.6	1.6	0.1
Irritable Bowel Disease (IBD)	1.5	3.5	9.4	2.0	-2.5	-0.5	-0.1	-0.5	3.1	2.6	1.7	-1.3
Ulcerative Colitis (UC)	1.6	3.0	9.7	1.8	-3.1	-1.0	-0.1	-0.5	2.5	1.5	0.9	-1.9
Major Depression (MDD)	0.6	0.7	3.3	-1.2	-0.4	-0.5	0.3	-0.8	0.1	-0.2	-0.7	-1.8
Reaction Time	0.3	0.5	2.5	0.3	0.6	0.8	-0.7	0.0	0.4	0.6	0.0	-1.6
Verbal and Numeric Reasoning (VNR)	1.0	2.3	7.1	2.7	0.4	1.1	1.7	0.7	1.0	2.1	1.8	0.7
Breast Cancer	0.2	0.4	2.0	-0.0	-0.7	0.4	-1.4	-0.5	0.5	-0.4	-0.1	-0.2
Ovarian Cancer	0.3	0.4	1.7	0.3	0.6	-0.5	-0.7	1.3	0.3	-0.7	-0.2	-0.4
Prostate Cancer	1.0	1.4	4.3	0.7	-1.2	0.4	1.5	2.1	1.3	0.2	0.6	-1.4
Age at First Birth	0.7	1.1	2.2	1.5	0.7	1.0	1.2	1.4	-0.8	-0.8	-0.0	1.2
Bipolar Disorder (2011)	0.7	0.7	2.8	-0.4	0.0	0.0	-1.4	-0.5	0.3	-1.7	-0.6	-0.6
Body Mass Index (BMI) (2010)	0.5	0.7	3.4	0.3	-0.3	-1.8	0.7	-0.5	-1.0	0.4	-0.6	0.5
Coronary Artery Disease (CAD)	0.3	0.4	1.5	-0.4	1.0	0.0	0.4	-1.2	-0.3	-0.0	-0.9	-0.3
Crohns Disease (2012)	0.6	1.0	3.6	0.9	0.0	0.0	0.7	1.5	1.9	1.4	0.1	-0.5
Mean Putamen Volume	0.5	0.6	1.6	0.6	-0.8	-1.3	0.6	0.7	0.4	0.5	-0.6	-0.9
Fasting Glucose	0.8	1.0	2.3	-0.8	0.1	-0.6	-1.5	-1.5	-1.3	0.2	0.6	-1.2
HbA1C	0.2	0.2	0.9	-1.0	-0.1	-0.7	-0.2	-0.3	0.3	-0.3	-0.4	-0.6
HDL Cholesterol	0.4	0.7	1.6	-1.3	-0.0	0.6	-1.2	-0.8	-0.6	-1.1	-0.8	0.5
LDL Cholesterol	2.0	3.2	8.5	-2.9	0.2	-1.1	-1.8	-0.6	-2.0	-2.0	-2.3	1.3
Lupus	0.4	0.5	1.4	0.0	-0.6	-1.0	0.6	1.0	0.1	-1.2	-0.5	0.7
Neuroticism (2016)	1.9	2.7	7.3	-1.7	-2.6	-2.1	-0.1	-1.1	0.9	0.1	0.7	-2.7
Primary Biliary Cirrhosis	0.8	1.1	2.9	-1.6	0.0	0.0	-1.5	0.1	-0.7	-1.7	-1.2	-0.3
Rheumatoid Arthritis	0.3	0.4	1.5	-0.6	1.2	0.0	-0.2	0.3	0.8	0.6	-0.1	-0.6
Schizophrenia (2014)	0.5	1.1	4.3	1.3	0.0	0.0	0.0	-1.4	2.1	0.9	0.2	-1.2
Triglycerides	0.2	0.4	1.2	0.3	0.8	0.2	0.1	1.1	-0.9	0.3	-0.2	0.4
Type 2 Diabetes (T2D) (2012)	0.6	0.7	3.0	0.8	-1.7	-1.0	0.9	-0.7	0.1	-0.2	-0.6	0.3
Ulcerative Colitis	0.3	0.5	1.3	1.0	0.0	0.0	-0.2	0.5	1.1	0.8	0.5	-0.8
Blood Eosinophil Count	0.1	0.7	2.0	0.9	-1.4	-0.5	0.5	-0.6	0.7	-0.4	1.2	0.5
Blood Platelet Count	0.3	3.7	12.7	0.3	-0.9	-2.0	-3.6	-2.6	-0.4	2.5	1.4	0.1
Blood Red Count	0.2	2.1	4.5	1.4	-1.7	-1.6	-0.4	-0.4	0.1	2.1	1.6	-2.1
Blood White Count	0.6	4.3	11.1	1.8	-1.0	0.0	1.7	0.5	3.0	3.3	2.2	-2.5
Heel T-Score	0.1	0.9	5.3	-0.5	-0.7	0.2	0.2	-1.3	-0.5	0.6	0.0	-2.3
BMI	1.2	7.1	33.6	0.8	-4.3	-5.8	0.1	-0.7	0.2	2.6	0.2	-2.0
Height	0.1	1.8	4.7	-1.3	1.6	1.0	1.9	0.8	-2.2	-1.2	-0.9	0.1
Waist Hip Ratio (WHR)	3.2	14.5	44.1	6.6	3.0	3.1	3.5	2.5	3.4	5.1	3.1	0.9
Systolic Blood Pressure	0.4	1.8	5.5	-0.4	-1.2	-2.4	-1.1	-2.1	-0.5	-1.1	-1.1	-0.6
Smoking Status	0.3	0.7	2.7	-0.2	-0.4	-0.3	0.3	0.6	1.6	0.8	-0.2	-1.3
Allergy or Eczema	4.6	12.1	23.3	4.8	-0.2	2.5	4.8	3.3	3.3	4.0	4.3	-0.5
Cardiovascular Disease	0.8	2.8	6.9	2.6	-1.8	-2.2	0.8	-0.9	1.2	1.6	1.4	-1.5
Hypothyroidism (self reported)	0.2	0.5	2.2	-0.3	-0.9	-0.6	0.3	0.9	1.5	-0.1	-0.0	-0.5
Respiratory disease	1.0	2.3	4.9	1.5	-2.2	-0.8	0.9	0.4	1.4	1.6	2.0	-1.8
Type 2 Diabetes (T2D) (2018)	0.9	1.7	4.3	1.7	-1.0	-1.8	0.4	-0.4	0.9	1.5	0.6	-2.1
Lung FEV1/FVC ratio	0.7	3.6	8.9	2.2	2.2	1.6	0.4	1.2	-1.2	3.0	2.0	2.0
Lung FVC	0.5	2.4	7.0	-0.6	1.9	1.9	-0.5	0.7	-1.4	-2.6	-2.0	0.8
Neuroticism	1.0	2.5	7.2	-1.4	0.5	1.2	1.7	1.6	2.5	0.0	0.0	-2.7
Chronotype (morning person)	0.2	0.4	2.1	0.3	-0.1	-0.6	0.7	-0.4	0.0	-0.6	-1.5	-0.0
Hair Pigment	0.0	1.4	3.6	-1.6	0.2	-1.9	-0.2	-1.4	-1.9	-0.5	-0.1	-0.6
Tanning	0.0	0.6	2.1	-0.7	-1.5	-0.6	-0.6	0.3	-0.8	-0.1	0.7	-0.9
Hand grip strength (left)	0.5	1.3	4.1	1.1	0.3	0.5	0.6	0.9	-0.1	2.0	1.6	-1.5
Number of treatments/medications taken	0.7	1.2	2.9	-0.2	-1.5	-1.6	0.3	-1.2	1.3	-0.0	0.2	-1.7
Average weekly spirits intake	0.7	0.9	2.5	-0.7	-1.1	-1.6	-0.9	-0.8	-0.9	-0.7	-0.3	-1.2
Sensitivity / hurt feelings	0.9	1.6	4.1	-1.4	0.9	1.5	1.3	0.4	1.5	0.9	-0.3	-2.0
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.4	-0.6	0.5	-0.5	-0.3	-0.0	-0.1	0.0	0.0	-0.2
Hearing difficulty/problems: Yes	0.4	0.6	1.7	0.0	0.5	0.3	-0.7	0.8	-0.9	1.1	1.3	0.5
Relative age of first facial hair	1.2	2.6	11.1	-0.9	-0.2	-1.3	-0.6	-0.9	-0.5	-2.3	-3.3	1.7
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.1	-0.7	-1.0	-1.8	-0.3	-1.2	-0.3	-2.0	-2.0	-1.7
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.6	0.2	-0.1	0.5	1.2	1.0	1.2	0.2	1.3	0.6
Ever had hysterectomy (womb removed)	0.6	0.7	2.3	-1.3	-0.5	0.0	-0.5	-0.3	-1.1	-1.5	-0.3	0.6
Systolic blood pressure, automated reading	0.7	2.1	5.9	-1.3	-1.8	-2.4	-1.3	-1.9	-1.1	-0.0	-0.7	1.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.6	1.9	-0.3	-0.8	0.3	-0.0	0.7	0.8	1.4	-0.6
Angina	0.2	0.3	0.6	0.2	0.4	0.2	-0.6	0.3	-0.1	0.7	0.8	-0.7
Medication for hormone replacement therapy	0.7	0.8	5.1	-2.2	0.1	0.6	-0.1	0.1	0.2	-1.1	-0.5	-0.6
Vitamin and mineral supplements	0.4	0.5	1.8	-0.7	-0.1	0.1	-1.4	-0.9	0.1	1.0	0.5	0.3
Supplements: Zinc	0.2	0.2	0.4	0.5	-0.2	-0.4	0.2	-0.4	0.6	0.7	0.5	0.6
Medication: Co-codamol	0.4	0.5	1.2	-1.0	-1.1	-0.6	-0.4	0.1	-0.1	-1.0	-0.6	0.0
Medication: Metformin	1.0	1.5	5.1	2.3	0.3	0.2	-0.8	0.2	-0.1	1.9	1.4	-1.3
Diabetes (father)	0.7	0.9	2.6	0.8	-0.1	-0.1	-0.1	0.1	1.2	1.5	1.6	-1.0
Diabetes (mother)	0.6	0.7	1.8	0.8	0.3	-1.3	0.9	0.4	-1.2	0.8	1.0	-0.5
Severe depression (siblings)	0.1	0.1	0.2	-0.3	0.4	0.4	0.3	-0.0	0.3	-0.1	0.2	-0.5
Pack years adult smoking proportion	0.8	1.2	4.0	0.0	1.7	0.5	0.0	0.2	0.9	2.0	1.5	0.6
Impedance of leg (right)	0.6	2.9	13.7	0.9	2.4	3.7	0.7	1.4	1.5	-0.6	0.9	-0.4
Leg fat-free mass (left)	0.6	3.3	17.2	-0.6	-2.4	-4.2	-0.1	-0.8	-1.5	1.5	-0.6	-0.8
Trunk fat percentage	0.3	1.2	4.1	-1.3	-1.2	-2.0	0.5	1.2	0.2	0.8	-0.3	-1.1
Hand grip strength (right)	0.4	1.1	4.3	0.8	0.1	0.1	0.9	0.4	-0.4	1.8	2.1	-0.9
Townsend deprivation index at recruitment	0.6	0.8	2.4	-1.0	-1.2	-1.6	-0.8	0.9	-0.7	0.3	-0.5	-0.2
Current tobacco smoking	0.5	0.8	2.3	0.7	-0.9	-0.4	-0.7	0.3	1.5	1.3	0.5	-0.8
Average weekly fortified wine intake	0.5	0.6	1.4	-1.2	0.4	1.0	-0.6	-1.0	0.6	-0.5	-0.7	0.7
Maternal smoking around birth	0.6	0.9	3.3	-0.1	1.8	1.2	0.1	0.1	0.0	0.7	0.8	1.6
Fed-up feelings	1.2	2.1	5.0	-0.3	-0.7	-0.2	1.0	0.4	2.2	2.2	1.7	-2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.1	-0.4	1.0	0.7	-0.3	1.4	0.6	-0.0	-0.5	-0.3
Relative age voice broke	0.9	1.4	6.5	0.1	0.4	0.5	-0.0	-0.1	-1.4	-1.0	-1.8	2.5
Taking other prescription medications	0.2	0.3	1.3	0.2	-0.1	0.0	0.5	-1.2	0.6	0.2	-0.0	-0.9
Age when periods started (menarche)	1.1	2.6	10.0	0.2	-0.2	-1.3	-0.7	-0.1	-0.2	2.7	3.2	-1.9
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.2	-1.1	-1.0	-0.5	0.5	-0.3	0.9	0.2	0.3	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	5.5	0.1	-0.1	1.1	1.2	-0.4	2.2	0.6	0.2	-2.4
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	4.3	-2.1	-1.1	-0.8	-0.5	0.2	-1.7	-1.8	-1.7	-0.3
Qualifications: CSEs or equivalent	1.5	2.0	5.0	-0.2	-1.8	-2.2	-0.7	-1.6	1.9	0.2	0.3	-1.6
Serious illness, injury or assault to yourself	1.3	1.6	4.8	-0.8	-0.7	-1.6	-2.2	-1.5	-0.4	-1.0	-0.9	-1.3
High blood pressure	0.7	2.0	4.1	2.0	-1.7	-2.0	1.1	-0.1	0.9	1.1	0.6	-1.7
Hayfever, allergic rhinitis or eczema	3.8	8.3	17.9	4.2	0.1	2.2	3.8	3.0	2.2	3.0	3.8	-0.6
Multivitamins +/- minerals	0.8	1.1	2.3	1.3	0.6	0.4	1.5	1.5	-1.5	-0.6	-0.2	0.4
Stomach or abdominal pain in last month	0.6	0.7	1.4	1.2	-0.5	-0.7	-0.7	-1.1	1.0	0.8	0.7	-0.3
Supplements: Glucosamine	0.4	0.5	2.2	0.5	0.1	-0.3	-0.4	0.3	-0.9	-0.7	-0.8	1.5
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	6.1	0.4	1.6	2.5	1.7	2.3	2.0	0.9	1.1	1.1
Medication: Atenolol	1.4	1.8	5.5	-0.6	-1.6	-1.8	0.1	-2.4	1.0	0.7	0.5	-1.6
Medication: Levothyroxine sodium	0.3	0.5	1.4	0.2	-0.8	-0.6	0.4	-0.5	1.2	-0.9	-0.8	0.4
Sitting height	0.4	2.7	8.4	-2.3	0.4	-0.4	-0.9	-0.4	-2.9	-2.4	-1.8	-0.9
Chronic bronchitis/emphysema (father)	0.9	1.0	3.7	-1.9	0.6	0.4	0.5	1.0	0.6	-1.1	-1.4	-0.0
High blood pressure (mother)	1.6	2.2	6.9	-0.7	-1.7	-2.2	1.1	-0.6	1.7	0.6	0.5	-2.6
Body mass index (BMI)	0.9	3.8	18.7	-0.6	-3.4	-4.3	-0.4	-0.2	-0.2	1.8	-0.2	-0.6
Impedance of leg (left)	0.6	2.7	12.3	0.3	2.8	3.5	0.1	1.3	1.1	-0.9	0.7	-0.2
Leg predicted mass (left)	0.6	3.2	16.7	-0.6	-2.4	-4.1	-0.1	-0.7	-1.6	1.4	-0.6	-0.7
Trunk fat mass	0.4	1.8	8.8	-1.2	-1.7	-3.0	0.5	0.6	-0.2	1.1	-0.4	-1.2
Waist circumference	0.5	2.0	6.7	1.3	-1.3	-2.6	1.1	1.4	0.1	2.1	-0.3	-0.2
Number of incorrect matches in round	1.2	2.0	6.2	1.9	-0.5	-1.2	0.6	-0.3	2.5	1.4	1.4	-1.3
Past tobacco smoking	0.2	0.4	2.0	0.5	-0.1	-0.1	-0.2	-0.6	-1.4	-0.3	-0.1	0.9
Alcohol usually taken with meals	0.6	0.9	1.8	1.3	0.9	0.0	1.2	0.2	0.6	1.3	1.3	-0.3
Nervous feelings	0.8	1.6	3.3	0.4	0.5	1.6	1.8	0.5	1.4	0.9	1.3	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	-0.4	-0.7	-0.4	0.5	-0.1	0.2	-0.7	-0.0	-0.8
Hearing difficulty/problems with background noise	1.0	1.6	4.0	2.0	1.4	1.1	0.9	1.2	1.0	1.6	1.1	0.1
Hair/balding pattern: Pattern 2	1.0	1.2	4.3	0.0	1.0	2.1	0.3	1.8	0.9	0.3	1.0	0.8
Had menopause	0.4	0.5	1.4	-0.6	0.8	0.4	0.3	0.1	0.2	-1.2	-1.1	0.9
Had other major operations	0.2	0.3	1.0	0.2	-0.4	0.3	-0.1	1.0	-0.1	-0.8	-0.7	0.4
Forced vital capacity (FVC)	0.4	1.4	6.0	-0.0	2.5	1.3	-0.4	0.4	-1.6	-1.0	-1.0	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.3	4.0	-0.3	0.1	1.0	0.6	-0.8	2.0	1.0	0.5	-2.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.0	-0.1	-0.9	-0.2	0.0	-0.8	1.7	1.2	1.1	-0.9
Qualifications: None of the above	1.4	2.9	5.3	-1.0	2.2	2.2	1.5	2.1	2.3	1.9	-0.1	0.0
Financial difficulties in last 2 years	1.7	2.3	4.8	-2.0	-2.2	-1.7	-1.6	-0.9	-1.1	-1.3	-0.5	-1.6
Mouth/teeth dental problems	1.5	2.4	10.0	1.5	-1.9	-3.2	-0.7	-1.2	-1.3	-0.5	0.1	1.1
Heart attack	0.7	0.9	3.6	-0.4	-0.2	0.2	1.9	0.3	-0.5	0.5	1.2	-1.5
Allergy	2.9	6.6	13.7	-3.5	0.6	-1.1	-3.5	-2.7	-2.0	-2.6	-3.7	1.4
Pain all over the body in last month	1.0	1.0	3.5	-1.6	-0.6	-0.0	1.1	-0.4	0.4	-1.1	-1.9	0.5
Diabetes (self-reported)	1.0	1.5	3.4	1.7	-1.3	-1.4	-0.1	-0.0	-0.0	1.8	1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	2.1	2.7	5.7	1.9	0.4	2.1	1.9	2.4	1.9	1.2	1.3	0.1
Medication: Ramipril	1.1	1.4	7.4	1.2	-1.0	-1.0	0.6	-0.2	0.6	0.8	0.8	-2.7
Medication: Simvastatin	1.1	1.6	6.0	-0.4	-0.7	-2.2	-1.1	-0.8	-0.0	0.5	0.7	-2.4
Fluid intelligence score	0.6	1.2	6.1	2.5	0.3	0.9	0.4	1.0	-0.4	0.9	0.8	0.8
Illnesses of siblings	0.8	1.1	2.9	0.1	1.0	-0.1	-1.7	-1.3	-1.1	1.2	0.9	1.1
Neuroticism score	1.3	2.8	6.2	-1.3	1.1	1.7	1.7	1.5	2.3	1.0	1.1	-2.5
Weight	0.7	3.5	18.1	-1.1	-2.7	-4.3	0.1	-0.3	-1.2	1.3	-0.7	-1.1
Impedance of arm (right)	0.5	2.1	10.6	0.1	2.2	3.2	0.3	0.9	0.8	-0.8	1.1	-0.6
Arm fat percentage (right)	0.6	2.4	9.7	-0.4	-2.4	-3.1	-0.1	0.5	0.3	2.0	0.5	-1.2
Trunk fat-free mass	0.6	3.5	17.1	-0.4	-2.2	-4.1	-0.1	-1.4	-1.7	1.6	-0.5	-1.3
Hip circumference	0.9	3.9	15.5	-2.6	-2.5	-3.9	-0.5	-0.2	-1.2	-0.5	-2.0	-0.8
Time employed in main current job	1.0	1.2	2.2	-0.1	-1.3	-1.5	0.3	-1.4	-1.2	-1.0	-1.0	-1.1
Alcohol intake versus 10 years previously	0.3	0.5	1.8	-0.8	-0.5	-0.0	0.1	-1.4	-0.1	0.9	0.3	-0.7
Father’s age at death	0.6	0.8	2.5	-1.6	0.3	0.5	-1.0	-1.0	-0.1	1.0	1.0	0.5
Worrier / anxious feelings	0.5	1.0	3.5	-1.9	0.7	0.6	0.9	-0.3	0.9	-0.2	-0.3	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	4.6	-2.0	0.4	-0.1	-2.1	-0.8	-0.7	-1.4	-1.4	-1.3
Falls in the last year	0.5	0.7	2.3	-1.1	-0.4	-1.5	-0.5	-1.4	-0.2	0.6	-0.1	0.5
Hair/balding pattern: Pattern 3	1.3	1.9	7.6	-2.8	0.5	-1.1	-0.9	-0.5	0.4	0.0	-0.7	-2.5
Number of live births	0.3	0.4	1.7	-0.8	-0.8	-0.4	-1.3	0.5	0.1	-0.2	-0.1	0.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	7.1	0.5	2.7	1.6	-0.3	0.7	-1.9	-0.3	-0.7	0.7
Pulse rate	0.4	0.7	1.6	1.3	1.2	1.0	-0.3	0.4	0.7	1.1	0.1	-0.7
Happiness	0.6	0.7	1.2	1.1	0.6	0.5	0.9	-0.2	0.6	1.1	0.8	-1.0
Noisy workplace	0.8	1.0	3.8	-2.0	-0.9	-0.3	-0.4	-1.7	0.8	-0.3	-0.6	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.1	1.0	0.1	0.8	0.0	0.1	1.0	-0.1	-0.1	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.9	0.2	0.1	-0.2	-1.2	0.1	-0.6	-1.1	-1.0	1.4
Mouth/teeth dental problems: Dentures	0.3	0.5	1.7	-1.3	0.2	0.1	-0.2	-0.2	0.2	-0.5	-1.1	-0.9
Asthma	0.7	1.3	3.7	0.8	-1.0	-0.6	1.9	-0.1	1.2	0.8	1.6	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.7	-1.3	-0.3	-0.2	-0.5	1.0	0.9	0.5	0.4	-0.6
Medication: Cholesterol lowering	1.3	1.9	7.4	0.6	-1.7	-2.2	0.0	-0.9	-0.3	0.5	1.0	-2.7
Depression (self-reported)	0.4	0.4	1.4	-0.6	-0.0	-0.3	-0.4	-0.1	0.2	-0.6	-1.2	-1.2
Medication: Lansoprazole	0.6	0.7	1.7	-1.1	1.0	0.2	-0.6	-1.1	-0.2	0.6	-0.2	-1.3
Prospective memory result	0.8	1.0	3.6	-1.9	0.8	-0.7	-0.6	-0.8	1.0	-0.2	-0.3	-1.4
Lung cancer (father)	1.3	1.6	4.1	-1.1	1.0	0.8	0.7	0.2	-1.5	-1.5	-1.5	2.0
Illnesses of mother	0.8	1.0	1.9	1.4	0.7	0.9	-0.9	-0.6	-0.5	1.2	1.1	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.9	0.8	2.2	1.1	-0.2	0.7	-1.4	-0.5	-1.0	0.6
Pulse wave Arterial Stiffness index	1.6	1.9	5.1	1.1	0.7	1.1	2.2	2.0	1.6	-0.2	-0.9	1.3
Impedance of arm (left)	0.6	2.7	13.7	-0.5	2.5	3.7	0.6	0.8	0.6	-1.6	0.6	-0.1
Arm fat mass (right)	0.8	3.4	16.6	-0.9	-2.7	-4.1	-0.3	0.0	-0.3	1.9	-0.1	-1.4
Trunk predicted mass	0.6	3.5	17.0	-0.4	-2.2	-4.1	-0.1	-1.4	-1.8	1.6	-0.5	-1.3
Standing height	0.1	1.2	3.5	-1.4	1.1	-0.4	0.9	-0.2	-1.9	-0.8	-1.0	-1.3
Length of working week for main job	0.7	0.8	4.1	-0.3	-0.0	1.3	-0.1	0.6	-0.9	0.1	-0.2	2.0
Exposure to tobacco smoke at home	0.4	0.4	1.5	-0.2	0.2	0.5	1.0	0.6	1.2	-0.3	-0.6	-0.5
Breastfed as a baby	0.7	0.9	2.3	1.3	0.1	0.1	1.2	1.5	1.2	0.4	0.3	-0.8
Tense / ‘highly strung’	0.5	0.8	2.3	-1.5	0.8	0.6	0.5	-0.5	1.1	-0.1	0.4	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.9	-0.2	-0.7	-0.4	0.7	0.1	0.4	-0.6	-0.7	-1.0
Hair/balding pattern: Pattern 4	0.9	2.2	5.6	1.8	1.6	1.1	1.3	1.2	0.3	1.8	2.4	0.7
Birth weight of first child	0.6	1.1	4.1	0.3	1.2	1.1	-0.1	1.1	-2.0	0.4	1.1	0.6
Peak expiratory flow (PEF)	1.0	2.2	4.3	2.1	1.9	1.3	0.4	1.4	-2.0	1.1	1.4	1.0
Pulse wave reflection index	1.3	1.6	4.3	1.3	-0.2	1.2	1.9	2.1	1.2	0.6	0.5	1.1
Ever highly irritable/argumentative for 2 days	1.2	1.5	6.5	0.7	-1.8	-1.2	-1.0	-2.5	-0.6	0.1	-0.1	0.2
Loud music exposure frequency	0.6	0.7	1.3	-0.6	0.9	0.7	-1.0	-1.1	1.1	0.0	0.4	0.8
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.7	0.5	0.1	-0.1	-0.8	-0.6	-0.7	0.2	0.8	-0.1
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	10.8	1.3	2.1	3.3	0.6	1.8	0.2	0.9	0.2	1.5
Blood clot in the leg (DVT)	1.4	1.9	5.9	-1.3	0.8	0.4	-1.0	0.7	-1.9	-2.4	-1.4	1.0
Medication: Paracetamol	0.8	1.4	4.8	-0.6	0.5	0.4	-0.8	-0.2	1.7	1.5	0.8	-2.2
Headache pain in last month	0.6	1.0	2.8	0.8	0.7	0.8	1.4	1.7	1.6	0.1	0.1	-0.6
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	6.1	-1.6	1.4	1.5	-0.2	1.2	0.3	-0.7	-0.9	2.5
Glaucoma (self-reported)	0.8	0.9	3.7	1.0	-0.6	0.8	1.5	-0.0	1.9	-0.2	0.1	-0.5
Gout (self-reported)	0.4	0.5	3.0	-0.4	1.1	0.4	1.7	-0.1	-0.3	-0.2	-0.4	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.4	-0.6	-0.3	-0.1	0.4	0.4	1.2	-0.4	-0.1	-0.0
Medication: Amlodipine	0.4	0.6	2.5	-0.2	-0.4	-0.7	0.0	-1.6	-0.5	-0.6	-0.7	0.9
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.5	0.5	-1.0	-0.6	1.9	-0.6	1.5	-0.5	0.1	-0.7
Birth weight	0.5	1.2	3.3	-0.4	-1.3	-1.2	-0.7	-1.8	-0.5	0.3	0.7	-1.6
Chronic bronchitis/emphysema (mother)	1.7	2.0	4.2	-1.9	0.8	0.1	-1.0	0.7	-0.9	-2.0	-2.0	1.9
High blood pressure (siblings)	1.1	1.5	7.0	0.0	-2.6	-1.0	1.2	0.1	1.5	-0.5	-0.4	-1.3
Forced vital capacity (FVC), Best measure	0.2	0.8	3.5	0.7	1.9	1.1	-0.2	0.4	-0.8	-0.6	-0.6	0.2
Body fat percentage	0.4	1.4	5.3	-0.9	-1.6	-2.3	0.5	1.1	0.4	1.1	-0.1	-1.0
Leg fat percentage (right)	0.5	1.7	5.9	-0.1	-2.1	-2.4	0.3	0.8	1.0	1.7	0.0	-0.6
Arm fat-free mass (right)	0.6	3.2	16.8	-0.7	-2.4	-4.1	-0.0	-0.9	-1.2	1.1	-1.2	-1.1
Exposure to tobacco smoke outside home	0.3	0.4	1.8	-0.0	-0.2	-0.3	0.5	1.3	1.2	0.1	-0.1	-0.6
Comparative body size at age 10	0.3	0.8	2.3	0.1	-1.1	-1.5	-0.2	-0.8	-0.9	-0.0	-1.3	0.7
Number of full brothers	1.0	1.3	3.1	-0.8	-1.4	-0.8	1.3	0.8	-0.1	-1.8	-1.6	-0.1
Worry too long after embarrassment	1.0	1.7	5.3	0.7	1.1	1.5	2.3	0.8	1.1	1.4	0.7	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	10.3	1.4	0.2	0.2	0.8	1.5	2.2	1.5	1.1	-3.2
Wheeze or whistling in the chest in last year	0.4	0.6	3.7	0.1	-1.9	-0.5	0.4	-0.4	0.7	-0.6	-0.0	-0.7
Number of children fathered	1.4	1.6	4.9	-1.2	1.3	2.2	2.1	1.2	0.4	0.1	-0.0	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.2	1.2	-0.1	0.2	1.1	-0.5	1.6	0.9	1.8	0.1
Age at first live birth	1.0	1.7	7.1	2.7	1.0	1.8	1.2	0.9	-0.7	0.7	1.0	-0.0
Pulse wave peak to peak time	1.5	1.8	4.5	-1.0	-0.6	-1.1	-2.1	-1.8	-1.7	0.3	0.9	-1.4
Health satisfaction	1.4	1.9	3.8	-1.1	-1.9	-1.3	0.5	-1.2	1.8	-0.9	-0.9	-1.9
Shortness of breath walking on level ground	0.3	0.4	1.5	-0.0	0.4	0.4	0.6	-0.2	0.9	-0.3	-0.5	-1.2
Qualifications: College or University degree	0.4	1.2	3.9	1.6	0.9	1.2	0.6	0.1	-1.2	-0.2	0.3	2.0
Eye problems/disorders: None of the above	0.3	0.4	1.3	1.1	0.3	-0.1	0.5	-0.4	-0.5	1.0	0.8	-0.0
Mouth/teeth dental problems: Loose teeth	1.2	1.4	4.5	0.8	0.4	1.4	-0.2	0.7	2.1	1.6	1.0	-1.2
Emphysema/chronic bronchitis	0.4	0.4	1.9	-1.4	0.1	-0.8	-0.3	-0.3	-0.7	-0.4	-0.5	-0.3
Medication for pain relief, constipation, heartburn	0.6	1.0	4.9	0.2	-0.4	-0.0	-0.1	-1.1	-1.4	-0.8	-0.3	2.2
Neck or shoulder pain in last month	0.8	1.1	3.0	-1.6	-0.4	-0.2	1.4	-0.2	1.7	-0.6	0.4	-1.4
Medication: Blood pressure	0.8	1.3	3.6	1.9	-1.0	-0.9	0.8	-0.7	0.7	1.0	0.7	-1.9
Angina (self-reported)	0.2	0.3	0.9	0.1	0.4	-0.1	-0.8	0.4	-0.2	0.5	0.6	-1.0
Migraine (self-reported)	0.4	0.5	2.3	1.5	-0.0	0.3	0.3	0.1	-0.3	0.2	0.8	0.9
Medication: Ibuprofen	0.6	0.7	2.4	-1.6	0.0	-0.1	-0.3	0.8	1.5	-0.2	-0.6	-0.5
Medication: Allopurinol	0.7	0.9	2.2	-0.8	0.8	-0.5	1.4	-0.3	-0.9	-1.3	-1.5	-0.6
Medication: Omeprazole	1.9	2.3	7.8	-1.3	-1.6	-2.8	0.2	-0.3	-0.4	-1.9	-1.9	-1.1
Medication: Seretide 50 evohaler	1.7	2.0	7.8	1.4	0.7	0.1	0.9	-0.7	1.6	1.9	2.8	-0.6
Mean time to correctly identify matches	0.5	1.0	2.6	0.8	1.6	1.6	0.0	-0.3	0.7	0.7	0.4	-1.6
Heart disease (mother)	0.6	0.7	3.5	-1.0	-0.5	0.0	1.9	-0.0	0.2	-1.1	-0.8	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	2.6	0.6	1.6	0.3	-0.2	1.3	0.1	0.9	1.1	0.1
Whole body fat mass	0.6	2.4	11.9	-0.9	-2.3	-3.5	0.4	0.3	-0.1	1.5	-0.3	-1.2
Leg fat mass (right)	0.8	2.9	13.2	-0.3	-2.8	-3.6	0.3	0.1	0.2	1.9	-0.1	-1.1
Arm predicted mass (right)	0.6	3.2	16.6	-0.9	-2.2	-4.1	-0.2	-1.0	-1.6	0.9	-1.3	-0.8
Pulse rate, automated reading	0.1	0.3	1.3	1.0	-0.1	-0.2	-0.4	0.3	0.1	-0.1	-1.1	-0.0
Alcohol intake frequency.	0.7	1.6	4.9	-2.2	0.3	-0.5	-1.0	-1.7	0.0	-0.0	-1.5	-1.7
Comparative height size at age 10	0.2	1.0	4.5	-0.5	0.5	-0.0	0.9	-0.9	-0.8	-1.1	-2.1	0.1
Number of full sisters	0.3	0.4	2.0	-0.5	-0.1	-0.3	-0.7	0.1	1.4	0.1	-0.4	0.4
Suffer from ‘nerves’	1.0	1.5	3.7	-0.2	0.6	1.9	1.4	1.3	1.6	0.5	0.1	-1.7
Overall health rating	0.5	1.0	3.0	-1.4	-0.4	-1.5	-0.8	-0.3	0.3	-0.6	-0.3	-1.7
Chest pain or discomfort	0.6	0.9	5.5	-0.5	0.2	-0.2	-0.2	0.9	0.9	0.4	0.4	-2.3
Had major operations	0.5	0.6	2.9	0.5	-0.2	-0.7	0.8	-0.0	-0.9	0.5	0.7	-1.7
Age at last live birth	1.3	1.8	4.6	2.1	1.0	2.1	1.3	1.6	-0.4	0.5	1.3	-0.1
Family relationship satisfaction	0.4	0.5	1.4	0.8	1.2	0.8	0.5	0.2	1.2	0.1	-0.5	-0.2
Leg pain on walking	0.7	0.8	2.9	0.6	-1.7	-1.1	-0.3	-1.4	0.4	0.7	0.4	-0.6
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.1	8.6	-1.3	-1.4	-2.9	-0.5	-1.6	-1.1	0.1	0.8	-1.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	-0.6	-0.2	-0.5	-1.2	0.4	-0.6	-0.1	0.0	0.8
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.5	0.5	0.7	1.1	1.1	0.8	-1.6	-0.4	-0.9	1.2
Medication: Aspirin	0.3	0.4	1.4	1.2	-0.5	-0.1	0.0	0.3	-0.7	0.7	0.7	-0.1
Supplements: Vitamin C	1.1	1.3	3.7	0.5	-1.9	-1.9	0.4	-0.7	1.4	0.5	0.4	-1.2
Knee pain experienced in last month	0.6	0.9	2.8	-0.8	-0.5	-1.0	-1.1	-0.3	-1.7	-1.0	-1.2	-0.2
Hypertension (Self-reported)	0.7	2.0	4.7	2.2	-1.8	-1.9	1.1	-0.0	0.9	1.3	0.8	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.3	-0.5	0.6	0.6	-0.1	-0.2	0.2	0.2	-0.3	-0.2
Illnesses of father: Heart disease	0.7	1.0	2.5	1.2	0.6	-0.1	1.2	1.6	-0.8	0.9	1.0	-0.9
Illnesses of siblings: Diabetes	0.7	0.8	2.6	0.8	0.6	0.6	1.4	1.6	0.8	0.6	0.6	-0.5
Smoking status: Previous	0.4	0.5	1.6	0.4	0.3	0.4	1.0	0.6	1.3	0.7	0.6	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	4.7	0.5	0.3	-0.6	-2.2	-0.0	-2.1	-0.6	-0.6	1.0
Whole body fat-free mass	0.6	3.6	18.2	-0.6	-2.3	-4.3	-0.2	-1.1	-1.8	1.5	-0.7	-1.1
Leg fat-free mass (right)	0.6	3.3	16.9	-1.1	-2.1	-4.1	-0.4	-0.9	-1.8	1.2	-0.8	-0.6
Arm fat percentage (left)	0.5	2.0	8.5	-0.5	-2.3	-2.9	0.2	0.4	0.3	1.7	0.3	-0.9
Average weekly red wine intake	0.2	0.3	0.9	0.1	-0.2	-1.0	0.3	0.6	-0.7	0.2	0.7	0.2
Handedness (chirality/laterality): Left-handed	0.7	0.9	2.5	0.7	1.2	0.8	0.3	0.2	0.5	1.2	1.6	-1.0
Mood swings	1.3	2.3	8.1	-1.2	0.6	0.4	0.9	0.9	2.5	1.1	1.3	-2.8
Loneliness, isolation	0.6	0.8	2.6	-1.6	0.6	1.2	0.7	0.7	0.5	-0.3	-0.9	-0.8
Long-standing illness, disability or infirmity	1.0	1.6	3.5	-1.3	-1.4	-1.9	1.6	-0.5	-0.3	-1.5	-1.0	-1.1
Ever had bowel cancer screening	0.3	0.4	1.3	0.1	0.1	-0.1	0.5	-1.2	0.9	-0.9	-0.4	0.2
Diabetes diagnosed by doctor	1.4	2.3	4.2	2.0	-1.6	-1.9	0.0	-0.1	0.0	2.0	1.8	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.0	0.8	0.4	0.5	-1.4	0.8	-0.6	1.0	0.2	0.2
Friendships satisfaction	0.9	1.1	2.6	0.5	1.5	1.4	0.8	0.7	0.8	1.6	1.1	0.1
Qualifications: nursing, teaching	0.6	0.9	2.0	1.3	1.4	0.7	0.3	0.7	-0.8	0.8	1.4	-0.1
Commuting to job workplace: Walk	1.1	1.2	4.2	-0.3	-1.1	-1.8	1.1	-0.0	0.9	-0.1	0.2	-2.0
Eye problems/disorders: Cataract	0.6	0.8	2.2	-0.9	-0.0	0.1	-0.7	1.5	-0.5	-1.2	-1.0	0.9
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	5.2	-0.2	1.9	2.1	1.2	1.1	2.3	0.7	0.7	-1.9
Medication for cholesterol	0.4	0.6	1.6	-0.9	0.4	0.8	-0.3	-0.3	-1.2	-0.8	-1.0	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.7	-0.6	1.1	-1.6	-1.3	0.1	-1.3	1.0	1.1	-1.3
Back pain experienced in last month	0.9	1.2	3.1	0.0	-1.0	-1.3	0.1	-1.4	0.5	1.1	1.3	-1.8
Mineral and other dietary supplements	0.6	0.8	2.8	-0.9	-0.3	-0.7	-1.7	-0.6	-1.2	-0.4	0.1	-1.0
Breast cancer (self-reported)	0.5	0.6	1.4	0.8	-0.4	-0.6	0.8	0.4	1.2	0.5	1.0	-1.1
Asthma (self-reported)	0.7	1.4	3.5	1.3	-0.9	-0.4	1.9	0.1	1.1	0.8	1.8	-1.1
Osteoporosis (self-reported)	0.5	0.6	2.6	-1.6	0.9	0.2	-0.8	-0.0	-0.4	-0.3	-0.7	-0.9
Osteoarthritis (self-reported)	0.2	0.3	0.6	0.5	0.2	-0.8	0.7	0.3	0.4	-0.6	-0.7	-0.3
Medication: Aspirin	0.5	0.6	2.3	1.5	-0.4	-0.4	0.2	0.1	-0.4	1.2	1.1	-0.2
Medication: Gliclazide	1.0	1.1	2.6	1.6	-0.2	-0.5	-0.0	1.4	-1.3	1.3	1.4	0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.5	0.3	0.5	-1.0	0.1	0.0	-0.2	0.3	1.2
Smoking status: Current	0.3	0.5	2.0	0.0	-0.8	-0.3	-0.8	-0.0	1.4	0.7	-0.1	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.0	0.6	0.7	1.0	0.4	0.0	-0.0	0.0	-0.1	0.1
Whole body water mass	0.6	3.5	18.3	-0.6	-2.3	-4.3	-0.3	-1.1	-1.7	1.5	-0.7	-1.1
Leg predicted mass (right)	0.6	3.3	17.1	-1.1	-2.1	-4.1	-0.4	-1.0	-1.9	1.2	-0.8	-0.6
Arm fat mass (left)	0.7	2.9	14.0	-0.8	-2.5	-3.7	0.0	0.3	-0.4	1.7	-0.2	-1.2
Number of self-reported non-cancer illnesses	1.0	1.8	4.0	2.0	-1.1	-0.8	1.5	0.3	1.7	1.1	1.3	-1.3
Average weekly champagne plus white wine intake	0.3	0.4	1.5	-0.2	-0.6	-0.9	0.1	-1.2	-0.8	0.0	0.3	-0.2
Miserableness	0.9	1.5	4.3	0.6	0.4	1.1	-0.4	0.5	2.1	1.4	1.5	-1.8
Guilty feelings	1.3	2.0	3.2	1.3	0.2	1.5	1.8	1.8	1.2	1.7	1.8	0.4
Wears glasses or contact lenses	1.1	1.2	4.2	-0.8	2.0	1.1	1.4	1.5	-0.8	-0.4	-0.1	0.3
Ever taken oral contraceptive pill	0.8	0.9	3.1	1.4	-0.8	0.3	0.6	0.3	-0.2	1.0	1.8	-0.8
Hearing aid user	1.0	1.1	3.6	0.7	0.6	0.5	1.3	1.1	0.5	1.2	1.9	-0.9
Mother’s age at death	1.1	1.4	5.1	-0.8	-1.3	-0.1	-0.3	-0.3	-0.0	-2.0	-2.3	1.0
Financial situation satisfaction	0.6	0.8	1.7	-0.8	-1.1	-1.3	0.1	-0.2	-0.7	-0.8	-1.2	-0.9
Tinnitus: Yes, now most or all of the time	1.8	2.1	5.0	0.3	1.6	1.3	2.1	2.2	2.1	0.2	0.2	-0.9
Commuting to job workplace: Public transport	0.8	0.9	1.6	-1.2	1.0	1.3	0.4	-0.5	-1.1	-1.2	-0.8	0.6
Eye problems/disorders: Glaucoma	1.5	1.8	4.5	1.1	0.7	2.0	2.1	0.9	2.1	0.4	0.6	-0.3
Medication: Blood pressure	0.5	0.9	3.0	1.0	-0.9	-1.2	-0.0	-0.3	1.1	0.7	0.5	-1.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.7	0.1	-0.3	-1.0	0.1	-0.4	-0.4	0.3	0.3	-1.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	2.2	0.7	0.6	0.8	1.5	0.5	0.9	0.6	0.5	0.5
High cholesterol (Self-reported)	0.6	1.1	4.6	-0.3	-0.2	-1.6	-1.2	-0.5	-0.5	0.3	-0.0	-2.1
Medication: Bendroflumethiazide	0.8	1.2	3.4	1.0	-1.3	-1.9	0.0	-1.2	1.1	0.6	0.6	-1.0
Medication: Paracetamol	0.5	0.8	2.3	-1.0	0.3	-0.3	-1.1	-1.0	1.2	0.8	-0.1	-1.5
Medication: Lisinopril	0.5	0.6	3.1	0.1	0.2	0.3	0.5	-0.1	1.0	-0.4	-0.9	-1.7
Medication: Atorvastatin	1.0	1.2	6.4	0.6	-0.7	-1.1	-0.1	-0.3	0.7	0.9	1.0	-2.5
Illnesses of father: High blood pressure	1.8	2.2	6.0	-0.8	-2.1	-1.9	-0.8	-1.8	0.2	1.1	0.4	-2.5
Alcohol drinker status: Never	1.0	1.2	4.3	-0.7	-0.7	-1.5	-0.2	-1.6	-0.3	-1.0	-2.1	0.6
Ever smoked	0.3	0.5	1.3	0.1	-0.0	0.2	-0.6	0.5	1.0	0.6	0.7	-1.2
Basal metabolic rate	0.7	3.7	19.2	-0.7	-2.5	-4.4	-0.3	-0.9	-1.8	1.5	-0.7	-1.0
Leg fat percentage (left)	0.5	1.6	7.2	-0.5	-1.9	-2.7	-0.1	0.7	0.6	1.6	-0.1	-0.4
Arm fat-free mass (left)	0.7	3.3	17.4	-0.6	-2.2	-4.2	-0.3	-0.6	-1.5	1.5	-0.9	-1.2
Number of operations (self-reported)	0.3	0.5	1.8	0.7	-0.1	0.4	1.4	0.9	-0.4	-0.6	-0.6	-0.7
Average weekly beer plus cider intake	0.8	1.2	4.5	-0.3	2.0	2.1	-0.2	0.8	0.9	0.3	-0.5	0.7
Irritability	0.8	1.3	2.9	-1.6	1.7	0.6	-0.3	1.1	1.3	0.8	1.1	-0.9
Risk taking	0.3	0.5	1.7	-0.2	0.8	1.1	0.5	1.3	0.4	0.2	-0.0	0.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.2	-0.9	-1.0	-0.3	-0.7	-1.5	-0.1	-1.5	-1.0	-0.1
Fractured/broken bones in last 5 years	0.4	0.5	3.4	-0.6	-0.4	-1.8	-0.3	-0.2	-0.2	-0.1	-0.5	-0.0
Age started oral contraceptive pill	1.3	1.7	5.2	-0.5	-1.4	-2.0	0.6	-0.8	0.2	1.4	0.7	-2.3
Diastolic blood pressure, automated reading	0.8	2.4	9.7	0.1	-2.6	-3.1	-0.9	-0.7	-1.1	0.7	0.3	1.3
Ever depressed for a whole week	0.9	1.1	2.2	-0.6	-1.2	-0.7	-1.5	-1.5	0.5	1.4	1.0	-0.3
Unable to work because of sickness or disability	1.0	1.3	3.6	-0.4	-0.4	-1.9	-1.5	-0.8	-1.3	1.2	1.1	-1.0
Commuting to job workplace: Cycle	1.1	1.3	3.9	0.1	1.7	0.7	1.9	0.2	2.0	-0.1	-0.9	-0.3
Myopia	1.3	1.8	3.9	1.4	2.0	1.7	0.9	0.9	0.2	2.0	1.4	-0.1
Vascular/heart problems diagnosed by doctor	1.0	2.8	6.0	-1.9	1.6	2.0	-1.2	1.0	-1.1	-1.7	-1.5	2.5
Cholesterol lowering medication	0.3	0.5	1.9	-0.5	0.6	-1.0	-1.4	0.1	0.3	0.2	-0.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	3.1	-0.8	-0.6	-1.8	0.9	0.7	-0.1	-1.2	-1.5	-1.4
Pain experienced in last month	0.5	0.9	2.5	1.2	0.9	1.0	-1.1	0.5	-0.8	0.4	0.2	1.6
Supplements: Calcium	1.0	1.1	2.3	-1.3	-0.7	-1.0	-1.0	-1.0	-0.7	-1.0	-1.0	-1.5
Basal cell carcinoma (self-reported)	1.0	1.2	6.9	0.5	-1.4	-0.0	2.6	0.8	1.0	-0.1	0.1	-0.1
Heart attack/myocardial infarction (self-reported)	0.8	1.0	4.3	-0.3	0.0	0.5	2.1	0.7	-0.4	0.5	1.2	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	5.0	-1.2	0.8	0.7	-1.1	1.1	-1.8	-2.2	-1.2	0.7
Heart disease (siblings)	1.5	1.9	5.2	0.6	0.7	1.0	2.3	1.9	1.9	0.2	0.3	-1.6
Alcohol drinker status: Previous	0.5	0.6	1.6	-0.6	0.2	-0.4	0.1	-1.2	1.0	1.3	0.5	-0.3
Pack years of smoking	0.7	1.0	3.4	-0.1	1.4	0.2	0.4	0.0	1.3	1.8	1.2	-0.0
Impedance of whole body	0.7	3.6	17.1	-0.2	2.9	4.1	0.5	1.5	1.1	-1.4	0.7	-0.3
Leg fat mass (left)	0.8	2.9	14.5	-0.4	-2.7	-3.8	0.1	-0.0	-0.0	1.9	-0.3	-1.0
Arm predicted mass (left)	0.6	3.1	16.4	-0.5	-2.2	-4.0	-0.3	-0.4	-1.3	1.4	-0.8	-1.2