TWAS hub - CCDC15

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2710	0.0440	4.9e-14	0.108	0.157	0.248	0.254	0.239	4.1e-13	1.1e-18	6.7e-30	1.0e-30	9.3e-29
2	GTEx	Adipose Subcutaneous	0.1840	0.0450	3.1e-05	0.097	NA	0.062	NA	0.070	2.3e-08	NA	7.9e-06	NA	2.3e-06
3	GTEx	Brain Cerebellum	0.2840	0.1010	9.5e-03	0.007	NA	0.104	NA	0.054	2.0e-01	NA	5.6e-04	NA	1.1e-02
4	GTEx	Breast Mammary Tissue (Male)	0.0434	0.1358	4.1e-01	0.000	NA	0.002	NA	-0.013	3.3e-01	NA	2.8e-01	NA	8.9e-01
5	GTEx	Lung	0.1171	0.0468	6.4e-03	0.031	NA	0.001	NA	0.021	1.8e-03	NA	2.6e-01	NA	8.5e-03
6	GTEx	Nerve Tibial	0.1250	0.0496	8.1e-03	0.035	NA	0.017	NA	0.055	1.6e-03	NA	2.2e-02	NA	9.3e-05
7	GTEx	Skin Not Sun Exposed Suprapubic	0.3740	0.0690	2.3e-07	0.109	NA	0.242	NA	0.285	1.5e-06	NA	1.8e-13	NA	5.5e-16
8	GTEx	Skin Sun Exposed Lower leg	0.3070	0.0500	2.0e-10	0.219	NA	0.245	NA	0.236	5.1e-18	NA	3.1e-20	NA	1.8e-19
9	GTEx	Testis	0.5850	0.0710	7.0e-12	0.660	NA	0.629	NA	0.653	4.1e-38	NA	3.4e-35	NA	1.9e-37
10	GTEx	Thyroid	0.1770	0.0470	4.5e-05	0.125	NA	0.212	NA	0.221	8.1e-10	NA	3.7e-16	NA	7.0e-17
11	GTEx	Whole Blood	0.0760	0.0280	2.1e-03	0.012	NA	0.013	NA	0.011	2.3e-02	NA	2.0e-02	NA	2.9e-02
12	METSIM	Adipose	0.0770	0.0233	4.9e-05	0.007	0.029	0.008	0.030	0.009	2.9e-02	2.6e-05	2.2e-02	2.1e-05	1.3e-02
13	ROSMAP	Brain Pre-frontal Cortex	0.2183	0.0410	1.7e-08	0.082	0.084	0.143	0.164	0.148	9.1e-11	5.7e-11	5.3e-18	1.3e-20	1.5e-18
14	YFS	Blood	0.1331	0.0211	0.0e+00	0.146	0.149	0.147	0.154	0.153	1.5e-45	2.7e-46	8.2e-46	7.3e-48	1.4e-47
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.1877	0.0596	4.7e-09	0.057	0.084	0.093	NA	0.090	4.5e-07	1.1e-09	1.3e-10	NA	2.5e-10
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1760	0.0720	4.9e-04	0.056	0.070	0.055	NA	0.049	3.8e-04	7.6e-05	4.1e-04	NA	8.9e-04
17	TCGA	Brain Lower Grade Glioma	0.0616	0.0353	7.4e-03	0.006	0.017	0.029	NA	0.025	6.8e-02	4.8e-03	2.9e-04	NA	6.3e-04
18	TCGA	Pheochromocytoma and Paraganglioma	0.1060	0.0570	9.7e-03	0.043	0.041	0.016	NA	0.041	7.9e-03	9.9e-03	7.5e-02	NA	9.9e-03
19	TCGA	Prostate Adenocarcinoma	0.1409	0.0492	6.9e-05	0.043	0.051	0.044	NA	0.028	2.6e-05	4.6e-06	2.0e-05	NA	5.2e-04
20	TCGA	Thyroid Carcinoma	0.1240	0.0440	3.3e-06	0.051	0.061	0.079	NA	0.077	1.0e-05	1.3e-06	3.7e-08	NA	5.4e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Number of full brothers	3.7	4.6	9.9	-3.0	-1.1	-0.6	-2.2	-2.1	-2.7	-1.5	1.0	-2.7	-1.7	-1.4	-3.1	-1.8	-2.1	-2.9	-2.2	-2.0	-2.3	-2.9
Gout (self-reported)	3.3	4.5	9.5	2.9	0.3	0.0	2.8	2.6	2.4	1.4	-0.3	3.1	2.5	1.7	2.8	2.2	1.8	2.3	2.5	2.3	1.8	2.3
Chronic bronchitis/emphysema (mother)	3.0	3.5	8.0	-2.2	-2.3	-0.9	-1.3	-1.8	-2.7	-2.3	2.0	-2.1	-0.4	-0.7	-2.8	-0.7	-1.9	-1.4	-2.4	-1.5	-2.1	-2.4
Heart disease (siblings)	2.9	3.6	7.6	-2.7	-0.6	-0.6	-2.2	-2.6	-2.1	-0.8	0.4	-2.8	-1.9	-1.7	-2.5	-2.1	-1.1	-2.0	-2.3	-2.4	-1.3	-1.8
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.2	7.9	2.7	1.3	1.6	1.8	2.8	2.6	1.7	-1.1	2.6	1.6	1.4	2.4	1.8	1.6	1.6	2.0	2.8	2.4	2.7
Ever had stillbirth, spontaneous miscarriage or termination	2.6	2.8	8.8	1.0	3.0	0.0	-0.8	0.7	2.2	2.7	-3.0	0.8	-1.7	1.7	1.8	-0.9	2.2	0.3	2.5	0.4	0.3	1.2
Medication: Atorvastatin	2.5	3.1	9.3	2.2	-1.4	0.2	2.9	1.6	0.8	-0.6	1.4	2.5	2.9	-1.1	1.7	3.0	0.0	1.6	1.4	2.0	0.7	1.7
Irritability	2.4	4.0	9.0	2.4	1.8	0.8	1.8	2.0	3.0	2.0	-1.8	2.5	1.5	0.3	2.5	0.9	1.6	1.7	3.0	2.4	2.1	2.7
Pulse wave reflection index	2.2	2.7	5.9	-2.4	-1.4	-1.2	-1.5	-1.7	-2.3	-2.1	1.1	-2.4	-1.2	-0.7	-2.4	-1.7	-1.5	-1.8	-1.2	-1.9	-1.0	-1.2
Serious illness, injury or assault to yourself	2.1	2.5	5.5	-2.2	-0.2	-1.5	-1.2	-2.4	-1.7	-1.3	0.5	-1.7	-1.4	-0.6	-2.1	-1.3	-2.2	-2.1	-1.5	-1.9	-0.9	-2.0
Worrier / anxious feelings	2.1	3.9	9.4	2.1	2.9	0.7	-0.1	2.0	3.1	2.2	-2.9	1.8	-0.2	1.2	2.4	-0.2	2.4	1.6	2.3	1.9	2.4	1.9
LDL Cholesterol	2.0	3.2	13.6	-0.6	-3.7	-0.4	1.4	-0.3	-2.3	-2.5	3.4	-0.3	2.4	-0.9	-1.7	1.7	-2.0	0.5	-0.7	-0.3	-2.6	-1.2
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	5.1	-2.1	0.5	0.1	-1.8	-1.9	-1.4	-0.5	-0.2	-2.2	-2.1	0.1	-1.5	-2.3	-0.9	-1.9	-1.2	-2.2	-0.5	-1.3
Bipolar Disorder (2011)	1.8	1.7	5.4	-1.4	0.0	0.1	-1.5	-2.0	-0.3	1.0	-1.2	-1.5	-2.3	-0.8	-0.9	-2.2	0.8	-1.6	-0.5	-2.3	-0.6	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	7.8	-2.7	-0.0	0.1	-2.8	-2.7	-2.2	-0.7	0.6	-2.8	-1.6	1.1	-2.4	-2.5	-2.5	-2.4	-1.9	-2.6	-0.8	-2.4
Father’s age at death	1.8	2.4	7.2	1.5	1.9	0.6	0.6	1.4	2.0	2.6	-2.0	1.3	-0.6	1.6	1.6	-0.3	2.6	0.2	2.7	0.9	0.3	1.6
Supplements: Glucosamine	1.7	2.2	7.6	-1.4	1.6	-1.9	-2.6	-1.4	-0.3	0.0	-1.6	-1.5	-2.8	-0.5	-0.6	-2.4	-0.7	-0.6	-0.9	-1.8	0.0	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	7.2	-0.3	2.7	1.7	-1.8	-0.3	1.0	2.0	-2.5	-0.7	-2.4	-0.1	0.3	-2.2	0.9	-0.9	0.5	-0.7	1.2	0.7
Ever had bowel cancer screening	1.7	2.0	8.6	0.5	2.9	0.3	-1.2	0.2	1.9	2.3	-2.7	0.2	-1.1	2.1	1.3	-1.4	1.6	-0.2	1.3	-0.2	0.6	0.7
Worry (Nagel 2018)	1.6	3.3	8.3	2.1	2.3	1.0	0.2	1.9	2.9	2.0	-2.5	1.9	0.1	0.5	2.2	0.0	1.9	1.7	2.3	1.9	2.3	1.9
Ulcerative Colitis (UC)	1.6	3.0	7.8	1.8	-0.1	1.4	2.6	2.2	1.6	0.8	-0.1	2.3	2.0	1.6	1.5	1.6	1.3	1.4	2.8	2.5	0.5	2.2
Coronary Artery Disease (CAD)	1.6	1.9	6.3	-1.7	1.0	-0.2	-2.4	-1.3	-0.9	-0.2	-0.8	-2.0	-2.1	-0.5	-1.5	-2.5	-0.3	-1.9	-1.1	-1.3	-0.6	-1.2
Irritable Bowel Disease (IBD)	1.5	3.5	9.0	2.2	1.0	1.6	2.3	2.2	2.2	1.8	-1.0	2.5	1.1	1.9	2.0	1.3	1.8	1.5	3.0	2.3	0.2	2.2
Major Depression (MDD)	1.5	1.8	3.6	-1.6	-0.2	0.5	-1.9	-1.4	-1.4	-0.2	0.1	-1.8	-1.6	0.5	-1.9	-1.6	-1.5	-1.8	-1.4	-1.6	-0.6	-1.9
Mean Putamen Volume	1.5	1.7	6.2	0.6	-2.4	0.3	2.1	0.7	-1.1	-1.6	2.5	0.6	2.1	-0.6	-0.3	1.9	-0.7	1.0	-0.9	1.0	-1.1	0.5
Diabetes (mother)	1.5	2.0	4.5	1.7	1.8	-0.2	1.1	1.1	2.1	2.0	-1.6	1.8	0.2	0.7	2.1	0.7	1.6	1.0	1.8	1.1	1.0	1.4
Noisy workplace	1.5	1.8	4.8	-1.4	0.9	-1.1	-1.9	-1.6	-0.7	0.0	-0.8	-1.5	-2.1	-1.2	-1.1	-1.7	-1.5	-0.6	-1.6	-2.2	0.4	-1.9
Osteoporosis (self-reported)	1.5	1.9	4.3	-1.7	-1.3	-1.6	-0.9	-1.2	-1.8	-1.3	1.0	-1.7	-0.5	-1.2	-1.8	-0.7	-0.8	-1.2	-1.8	-0.8	-1.7	-2.1
Medication: Gliclazide	1.5	1.7	5.9	0.5	2.4	0.4	-0.4	0.2	1.8	2.4	-2.4	0.5	-1.1	1.3	1.4	-1.0	1.9	-1.2	1.0	0.2	0.8	0.9
Medication: Lisinopril	1.5	2.0	4.9	-1.9	-0.8	-1.2	-1.1	-1.2	-1.9	-1.7	1.1	-1.7	-0.8	-0.7	-2.0	-0.8	-1.9	-1.1	-1.8	-1.2	-0.7	-2.2
Schizophrenia (2014)	1.4	3.0	7.5	-2.5	-0.2	0.8	-2.2	-2.2	-1.6	0.5	-0.1	-2.7	-2.1	-0.4	-2.7	-2.3	-0.6	-2.2	-2.1	-2.1	0.1	-1.4
Impedance of arm (right)	1.4	6.4	19.9	2.3	3.2	4.5	-0.2	1.5	3.3	4.0	-3.5	1.6	-0.8	2.8	2.9	-0.6	3.3	0.7	3.7	0.9	1.0	2.3
Medication: Ibuprofen	1.4	1.7	4.5	1.4	0.3	1.2	1.2	2.1	1.2	1.0	-0.3	1.6	0.8	1.0	1.2	1.1	1.6	1.5	1.1	2.1	0.7	2.0
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	6.5	1.9	-0.2	-0.1	1.7	1.4	1.1	0.3	0.1	1.8	1.3	-1.0	1.7	1.5	0.8	2.5	1.2	1.1	1.2	1.2
Number of self-reported non-cancer illnesses	1.4	2.5	4.9	-2.2	-1.2	-0.6	-1.1	-2.0	-2.1	-1.1	1.1	-2.0	-1.3	-1.6	-2.2	-1.3	-1.6	-1.6	-1.9	-2.1	-1.0	-1.5
Leg fat percentage (left)	1.4	5.2	14.1	-1.9	-3.4	-3.0	0.3	-1.9	-3.0	-3.8	3.2	-1.7	1.0	-3.0	-2.8	0.3	-3.0	-0.9	-2.8	-1.5	-0.6	-1.7
Cholesterol lowering medication	1.4	2.0	4.3	-2.1	-1.0	1.0	-1.1	-2.0	-1.7	-0.5	0.7	-1.9	-0.8	-1.2	-2.0	-1.4	-0.9	-1.7	-1.4	-1.9	-1.3	-1.6
Alzheimer’s Disease (in mother)	1.3	1.5	3.6	1.6	1.0	1.6	0.8	1.1	1.8	1.2	-1.0	1.6	0.7	0.7	1.8	0.9	1.2	0.9	1.9	1.2	1.0	1.1
Eye problems/disorders: Diabetes related eye disease	1.3	1.5	2.9	-1.3	-1.1	-1.7	-0.4	-1.0	-1.6	-1.5	1.2	-1.2	-0.0	-1.7	-1.6	-0.4	-1.7	-1.0	-1.4	-1.0	-0.9	-1.2
Maternal smoking around birth	1.3	1.9	4.3	-2.1	-0.3	-1.1	-1.4	-1.8	-1.4	-1.1	0.2	-1.9	-1.8	-0.3	-1.7	-1.9	-1.2	-1.7	-0.3	-1.8	-1.2	-1.1
Time employed in main current job	1.3	1.4	6.6	-0.6	-2.2	-0.8	-0.0	-0.8	-1.8	-1.7	2.0	-0.8	0.5	-0.9	-1.2	0.5	-0.8	0.2	-1.0	-0.6	-2.6	-0.7
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	5.1	1.3	0.1	1.4	1.2	2.2	1.1	0.9	-0.1	1.6	0.9	1.4	1.0	1.1	1.5	1.4	1.4	2.3	0.3	1.9
Illnesses of mother	1.3	1.7	3.8	-1.7	-0.6	0.4	-1.1	-1.3	-1.9	-1.6	1.0	-1.9	-0.9	0.1	-1.9	-1.2	-0.5	-0.8	-1.7	-1.3	-1.6	-1.2
BMI	1.2	6.9	18.7	-1.6	-4.2	-4.3	1.1	-1.4	-3.4	-4.2	4.3	-1.2	1.9	-2.3	-3.0	1.5	-3.0	-0.4	-3.5	-0.7	-1.1	-1.8
Medication: Co-codamol	1.2	1.4	3.5	-1.2	-1.5	-0.1	-0.1	-0.8	-1.7	-1.5	1.6	-1.0	0.5	-0.4	-1.9	0.1	-1.7	-0.8	-1.6	-0.6	-1.5	-1.6
Severe depression (siblings)	1.2	1.4	4.4	1.3	-1.3	-0.8	2.0	1.0	0.1	-1.4	1.4	1.4	2.0	-0.5	0.6	2.1	0.4	1.4	0.1	1.0	-0.5	0.6
Fluid intelligence score	1.2	2.4	9.2	1.5	1.3	1.9	1.0	1.0	1.8	1.9	-1.2	1.4	0.7	0.7	1.7	0.7	3.0	0.2	2.8	1.1	0.0	2.3
Impedance of arm (left)	1.2	5.6	20.7	1.9	3.3	4.5	-0.5	1.3	3.0	3.6	-3.3	1.2	-1.1	2.9	2.6	-0.8	2.9	0.7	3.0	0.7	1.2	2.0
Tense / ‘highly strung’	1.2	1.9	4.5	1.7	1.7	0.1	0.6	1.5	2.1	1.5	-1.5	1.7	0.4	-0.1	1.7	0.6	1.3	1.3	1.3	1.7	2.1	1.4
Leg fat percentage (right)	1.2	4.2	11.3	-1.7	-2.9	-2.9	0.3	-1.6	-2.6	-3.4	3.0	-1.4	1.1	-2.6	-2.4	0.4	-2.7	-0.8	-2.6	-1.2	-0.5	-1.7
Medication: Seretide 50 evohaler	1.2	1.4	6.4	-1.5	-0.5	-2.0	-0.7	-1.2	-1.2	-1.2	0.5	-1.2	-0.6	-2.5	-1.0	-0.8	-0.5	-1.1	-1.9	-1.2	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	1.2	1.3	3.9	-0.9	-1.4	-2.0	-0.3	-1.1	-1.3	-1.2	1.3	-0.8	0.4	-1.4	-1.3	0.2	-1.6	-0.9	-1.2	-0.8	-1.1	-1.5
Handedness (chirality/laterality): Left-handed	1.2	1.5	4.5	1.7	-0.3	-0.2	1.4	1.8	1.0	0.5	0.2	1.8	1.6	-0.4	1.6	1.6	0.5	2.1	0.9	1.7	-0.0	0.4
Smoking status: Current	1.2	1.9	7.0	-1.8	-0.8	-1.1	-0.8	-1.4	-1.7	-1.2	1.0	-1.5	-0.4	-1.3	-1.7	-0.9	-2.6	-1.1	-2.0	-1.5	0.3	-1.2
Alcohol drinker status: Previous	1.2	1.4	6.1	0.9	-1.7	0.4	1.9	0.4	-0.3	-1.2	1.8	1.0	2.5	0.8	0.2	1.8	-0.4	1.4	0.8	1.0	-1.0	0.5
Number of treatments/medications taken	1.1	1.9	4.6	-2.1	-0.2	-0.3	-1.5	-1.7	-1.4	-0.2	0.1	-1.8	-1.8	-1.0	-1.6	-2.0	-1.3	-1.3	-1.2	-2.0	-0.6	-1.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.1	-1.3	-1.6	-1.6	0.3	-0.2	-1.5	-1.6	1.5	-0.9	0.5	-0.9	-1.9	-0.1	-1.4	-0.9	-0.5	-0.0	-2.0	-1.1
Average weekly fortified wine intake	1.1	1.3	5.9	1.3	1.1	0.8	0.2	1.1	1.4	1.0	-1.2	1.0	-0.4	2.4	1.6	-0.0	1.2	1.3	1.8	0.3	0.5	1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	6.2	-1.9	-0.7	-0.0	-1.8	-2.0	-2.1	-0.9	1.2	-2.1	-0.5	1.3	-2.1	-1.5	-2.5	-1.6	-1.6	-1.9	-0.4	-1.9
Falls in the last year	1.1	1.5	5.1	0.5	2.2	-0.4	-0.4	0.6	1.6	2.1	-2.3	0.5	-1.4	-0.3	1.0	-0.9	1.6	-0.4	1.4	0.3	0.8	1.3
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	10.8	2.7	-1.3	1.2	2.9	2.1	0.9	-0.6	1.5	2.6	2.7	1.6	1.8	3.3	-0.1	2.9	0.6	2.4	1.4	1.7
Mouth/teeth dental problems: Dentures	1.1	1.9	4.7	-2.1	0.1	-0.5	-1.5	-1.4	-1.6	-0.9	0.3	-2.0	-1.2	0.9	-1.7	-1.9	-1.7	-1.1	-2.2	-1.4	-0.1	-1.4
Eye problems/disorders: None of the above	1.1	1.3	4.1	1.0	2.0	-0.3	0.1	-0.0	1.7	1.6	-1.8	0.8	-0.3	1.4	1.3	-0.4	1.8	-0.1	1.5	0.4	0.5	1.0
Loneliness, isolation	1.1	1.5	4.5	1.6	0.6	0.6	1.3	2.1	1.3	0.5	-0.4	1.5	0.9	1.1	1.1	1.1	0.7	1.0	1.1	1.8	1.8	1.6
Breast cancer (self-reported)	1.1	1.3	5.0	-0.1	-2.0	-1.5	1.0	0.6	-1.2	-2.2	2.1	0.0	1.5	-0.7	-0.6	1.4	-1.0	1.0	-1.1	0.3	-0.5	-0.2
Frequency of depressed mood in last 2 weeks	1.0	1.3	3.8	1.4	1.2	0.5	0.5	1.5	1.5	1.4	-1.1	1.1	0.0	1.7	1.1	0.4	1.1	0.6	0.9	1.2	2.0	1.5
Medication for hormone replacement therapy	1.0	1.1	3.7	-1.0	-1.9	0.1	0.1	-0.0	-1.5	-1.6	1.6	-0.7	0.5	0.4	-1.3	-0.1	-1.6	-0.3	-0.7	-0.2	-1.4	-1.3
Alcohol intake versus 10 years previously	1.0	1.5	5.0	0.5	-2.0	0.5	1.9	1.3	-0.6	-1.0	2.0	0.7	2.2	1.5	-0.1	1.5	-0.5	1.4	0.3	1.3	-0.5	0.5
Worry too long after embarrassment	1.0	1.7	5.6	-0.4	2.4	-0.1	-2.0	-1.1	0.9	1.6	-2.3	-0.8	-2.0	0.4	-0.0	-2.2	0.3	-1.3	0.2	-1.3	0.9	0.0
Medication: Allopurinol	1.0	1.3	3.0	1.6	0.2	-0.6	1.7	0.9	1.2	0.2	-0.0	1.7	1.7	-0.6	1.3	1.4	0.6	1.4	0.7	0.9	1.7	1.1
Alcohol intake frequency.	1.0	2.3	7.2	-0.3	-2.7	-1.3	1.3	-0.2	-1.6	-2.1	2.6	0.0	1.9	-1.8	-1.1	1.5	-1.5	0.6	-1.3	0.2	-2.0	-1.5
Age at last live birth	1.0	1.4	4.6	-0.9	-2.1	-0.1	0.6	-1.0	-1.7	-1.4	2.1	-0.7	1.2	-1.6	-1.5	0.7	-1.0	-0.3	-1.7	-0.4	-0.8	-0.4
Long-standing illness, disability or infirmity	1.0	1.6	5.6	-1.4	-2.0	0.0	0.5	-0.8	-1.7	-1.1	1.8	-0.9	0.7	-2.4	-1.8	-0.1	-1.2	-0.8	-1.2	-0.3	-1.6	-0.8
Medication for cholesterol	1.0	1.5	3.5	1.8	1.2	-1.1	0.7	1.2	1.7	0.9	-0.9	1.6	0.8	0.5	1.9	1.1	1.6	1.0	1.1	1.4	0.8	1.5
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.9	-1.6	-0.0	1.1	-1.1	-1.1	-0.9	-0.2	-0.2	-1.7	-1.2	-0.4	-1.4	-1.7	-0.5	-1.6	-0.1	-1.4	-1.5	-0.6
Leg fat mass (left)	1.0	3.8	10.5	-1.0	-3.2	-3.1	1.3	-1.0	-2.3	-3.2	3.1	-0.6	1.4	-3.1	-1.9	1.2	-2.3	0.2	-2.1	-0.7	-0.2	-1.0
Prostate Cancer	0.9	1.3	4.8	-0.8	0.5	-2.2	-1.3	-0.9	-0.0	-0.2	-1.3	-1.0	-2.1	-1.4	-0.3	-1.5	0.5	-0.6	0.9	-1.6	-1.3	-0.4
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.3	-1.6	-0.3	-0.0	-1.2	-0.8	-1.2	-0.1	0.1	-1.7	-1.4	0.6	-1.5	-1.8	-0.6	-1.1	-1.0	-1.1	-0.5	-1.3
Diabetes (father)	0.9	1.1	5.3	0.6	-1.3	-1.1	1.4	0.8	-0.2	-1.0	1.6	0.8	2.3	0.0	0.1	1.6	-0.7	1.1	0.0	1.2	0.2	0.6
Current tobacco smoking	0.9	1.5	6.2	-1.6	-0.9	-0.9	-0.6	-1.1	-1.6	-1.2	1.2	-1.3	-0.1	-1.1	-1.5	-0.6	-2.5	-0.8	-2.0	-1.2	0.3	-1.2
Sitting height	0.9	6.7	15.5	3.6	-0.6	-0.4	3.9	3.0	2.1	-0.1	0.6	3.9	2.8	-1.7	3.2	3.7	2.2	3.5	2.5	3.0	1.3	2.9
Body mass index (BMI)	0.9	3.9	10.2	-1.5	-3.1	-3.2	0.8	-1.2	-2.6	-3.2	3.0	-1.1	1.1	-2.4	-2.3	0.8	-2.3	-0.1	-2.2	-0.9	-0.9	-1.5
Medication: Simvastatin	0.9	1.3	3.1	-1.6	-0.1	-0.2	-1.3	-1.5	-1.0	-0.1	-0.1	-1.6	-1.2	-1.8	-1.2	-1.7	-1.3	-1.1	-1.2	-1.6	-0.1	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	6.2	2.5	-0.5	0.7	2.5	1.8	1.2	-0.1	0.6	2.5	1.8	1.1	1.9	2.5	0.3	2.5	1.4	2.1	1.5	1.9
Loud music exposure frequency	0.9	1.0	3.6	0.5	-1.5	0.1	1.4	0.7	-0.5	-1.2	1.6	0.8	1.9	0.9	-0.4	1.6	-0.7	0.9	0.1	1.0	-0.8	-0.1
Number of children fathered	0.9	1.1	3.6	-1.3	0.1	-0.8	-1.4	-1.5	-0.8	0.0	-0.2	-1.3	-1.0	-0.0	-1.2	-1.2	-0.4	-1.9	-1.6	-1.1	-0.6	-0.8
Pulse wave peak to peak time	0.9	1.0	5.9	1.0	1.2	2.4	0.2	0.2	1.2	2.1	-1.1	0.8	-0.4	0.5	1.0	0.1	0.7	0.3	0.8	0.6	0.7	0.8
Shortness of breath walking on level ground	0.9	1.0	5.6	-1.0	-0.7	-0.6	0.2	-0.8	-1.2	-0.9	1.1	-0.8	-0.0	-1.8	-1.3	0.0	0.5	-1.2	-0.9	-0.6	-2.4	-0.7
Leg fat mass (right)	0.9	3.6	10.8	-0.8	-3.0	-3.3	1.4	-0.8	-2.1	-3.1	3.0	-0.4	1.6	-2.9	-1.6	1.4	-2.2	0.3	-1.9	-0.4	-0.3	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.4	-1.0	1.3	0.9	-1.3	-1.0	-0.0	1.2	-1.3	-1.1	-1.7	0.6	-0.7	-1.8	0.5	-1.6	-0.3	-0.9	-0.1	-0.2
Mother’s age at death	0.9	1.1	4.5	0.7	2.1	-0.8	-0.2	-0.1	1.6	1.5	-2.0	0.6	-1.0	-0.5	1.2	-0.7	1.0	0.4	0.8	-0.2	1.1	0.7
Unable to work because of sickness or disability	0.9	1.2	3.4	-1.8	-0.1	-1.2	-1.4	-0.4	-1.3	-0.9	0.3	-1.4	-0.9	-0.4	-1.3	-1.0	-0.3	-1.7	-1.9	-0.3	-0.8	-1.3
Bipolar Disorder or Schizophrenia	0.8	1.9	4.5	-1.9	0.2	1.2	-1.9	-1.8	-0.8	1.5	-0.7	-2.0	-1.8	-0.2	-1.7	-2.1	-0.1	-1.7	-1.2	-1.9	0.2	-0.9
Neuroticism (Nagel 2018)	0.8	1.9	5.1	1.6	1.8	-0.4	0.3	1.3	2.3	1.5	-1.9	1.4	0.2	0.5	1.4	-0.1	1.0	0.9	2.0	1.3	2.1	1.9
Verbal and Numeric Reasoning (VNR)	0.8	2.0	7.3	1.3	1.1	1.6	1.0	0.7	1.5	2.1	-1.2	1.2	0.1	1.2	1.4	0.3	2.7	0.2	2.6	0.8	-0.1	2.2
Blood Red Count	0.8	8.0	29.5	0.0	-5.4	-1.8	3.0	0.5	-2.8	-4.5	5.1	0.5	3.8	-3.6	-1.6	3.5	-3.2	1.1	-2.2	1.0	-1.5	-1.2
Townsend deprivation index at recruitment	0.8	1.1	2.5	-1.6	-0.3	0.9	-1.1	-0.9	-1.1	-0.9	0.5	-1.6	-0.6	1.5	-1.5	-0.8	-0.8	-1.3	-1.5	-0.7	-0.7	-1.1
Qualifications: A levels/AS levels or equivalent	0.8	1.8	5.4	1.9	0.4	0.9	1.3	1.1	1.5	1.1	-0.7	1.6	1.0	0.1	1.6	1.1	2.0	1.1	2.0	1.5	0.5	2.3
Pulse wave Arterial Stiffness index	0.8	0.9	5.4	-0.8	-1.3	-2.3	0.0	0.1	-1.1	-2.1	1.2	-0.6	0.5	-0.6	-0.8	0.1	-0.5	-0.0	-0.6	-0.4	-0.8	-0.5
Medication: Paracetamol	0.8	1.4	2.9	-1.6	-1.0	-1.7	-0.9	-1.3	-1.6	-0.8	0.8	-1.5	-1.0	-1.2	-1.6	-1.1	-1.0	-1.7	-0.8	-1.0	-1.1	-0.7
Comparative body size at age 10	0.8	2.2	5.5	-1.5	-2.3	-2.2	0.6	-1.3	-2.1	-1.6	2.1	-1.2	0.3	-0.9	-2.0	0.2	-1.1	-0.8	-0.9	-1.2	-2.2	-1.6
Suffer from ‘nerves’	0.8	1.3	4.5	-1.2	0.7	-0.2	-2.1	-0.7	-0.5	-0.2	-0.9	-1.4	-1.8	-1.4	-1.2	-1.8	-0.4	-1.4	-1.3	-0.7	0.7	-1.0
Wears glasses or contact lenses	0.8	0.9	3.0	-0.5	-1.2	-1.7	0.0	-0.0	-1.1	-1.6	1.3	-0.4	0.4	-1.7	-0.8	0.3	-1.7	-0.1	-0.7	-0.1	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	0.8	1.0	4.2	-0.5	-0.9	-0.4	-0.3	-1.0	-1.0	-1.4	0.9	-0.6	0.0	-2.0	-0.7	0.1	-1.4	-0.2	-1.5	-0.8	-1.3	-1.4
Impedance of whole body	0.8	4.0	14.7	1.5	2.9	3.8	-1.0	0.7	2.5	2.8	-3.1	0.7	-1.2	2.2	2.2	-1.2	2.2	-0.1	2.5	0.3	1.3	1.8
Intelligence (Savage-Jansen 2018)	0.7	2.1	6.5	1.1	1.2	2.5	0.5	0.5	1.5	2.1	-1.3	0.9	0.3	2.2	1.2	0.1	2.5	0.5	2.5	0.4	-0.2	1.7
Schizophrenia (2018)	0.7	1.5	3.9	-1.4	0.6	1.4	-1.8	-1.2	-0.3	1.8	-1.0	-1.6	-1.7	0.8	-1.3	-2.0	-0.1	-1.5	-0.5	-1.4	0.7	-0.5
Schizophrenia vs Biploar Disorder	0.7	1.0	2.4	-1.4	-0.3	0.8	-1.3	-0.6	-1.1	0.0	0.3	-1.5	-1.0	-0.1	-1.6	-1.2	-0.8	-1.3	-1.0	-1.0	-0.7	-1.2
Alzheimer’s Disease (in father)	0.7	0.7	1.6	-1.1	-0.2	-1.3	-0.7	-1.0	-0.9	-0.9	0.2	-1.1	-0.8	-0.9	-0.8	-1.2	-0.0	-0.4	-0.8	-1.2	-0.7	-1.1
HbA1C	0.7	0.8	2.4	1.0	-0.4	0.4	-0.5	1.5	0.3	-0.3	0.6	0.6	1.4	1.5	0.7	1.3	-0.9	0.3	0.3	1.5	0.8	-0.7
Heel T-Score	0.7	5.5	13.3	-2.1	2.3	2.7	-3.4	-3.0	-0.7	1.9	-1.4	-2.3	-2.6	3.5	-1.3	-3.5	-0.8	-3.6	-0.6	-3.2	0.2	-1.8
Systolic blood pressure, automated reading	0.7	2.2	8.8	-0.2	2.9	-1.4	-2.0	0.1	1.6	2.0	-3.0	-0.3	-2.1	-0.9	0.8	-1.9	1.3	-0.5	0.5	-0.3	1.0	0.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.9	1.0	-0.8	0.7	1.4	0.5	-0.0	-0.5	1.2	0.9	1.5	0.9	0.3	1.7	-0.5	1.3	0.2	0.8	-0.3	0.4
Forced vital capacity (FVC)	0.7	2.5	8.5	2.0	-1.6	0.7	2.4	1.4	0.1	-1.0	1.9	1.9	2.3	1.0	1.0	2.9	-0.8	2.4	-0.2	1.8	1.0	1.0
Medication: Ramipril	0.7	0.8	3.3	0.3	1.5	-0.3	-0.6	-0.1	1.0	1.4	-1.5	0.2	-1.2	-0.9	1.3	-0.9	0.2	-0.4	0.2	-0.5	1.8	0.6
Neuroticism score	0.7	1.4	3.6	1.0	1.8	0.0	-0.3	1.3	1.9	1.5	-1.9	0.8	-0.0	0.9	1.1	-0.5	1.5	0.1	1.6	1.1	1.3	1.3
Breastfed as a baby	0.7	0.8	3.2	-0.1	1.8	-1.1	-1.4	-0.4	1.0	1.3	-1.8	-0.4	-0.7	0.4	0.4	-1.1	1.0	-0.3	-0.2	0.1	1.0	0.2
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.2	1.3	-0.1	0.9	0.9	1.4	1.1	0.1	-0.4	1.1	0.8	-0.1	1.2	1.1	1.0	0.3	1.5	1.3	0.3	1.5
Medication: Ventolin 100micrograms inhaler	0.7	1.0	3.3	-1.2	0.7	-0.5	-1.4	-1.4	-0.3	0.5	-0.7	-1.2	-1.1	0.5	-0.8	-1.5	-0.5	-1.8	-0.9	-1.2	0.8	-0.3
Birth weight	0.7	1.4	3.7	1.9	0.1	0.8	1.8	0.5	1.4	0.7	-0.2	1.9	1.5	-0.2	1.4	1.7	0.8	1.5	1.3	0.9	0.2	1.2
Age at first live birth	0.7	1.2	4.3	0.2	-2.1	0.4	1.1	-0.1	-1.0	-0.7	2.1	0.2	1.9	-1.8	-0.7	1.7	-0.5	1.2	-1.1	0.2	-0.8	-0.0
Medication: Omeprazole	0.7	0.9	2.2	-1.3	0.5	0.2	-1.2	-1.0	-0.6	-0.0	-0.4	-1.2	-1.4	-0.4	-1.0	-1.4	-0.3	-1.1	-0.7	-1.5	-0.3	-1.2
Pulse rate, automated reading	0.7	2.4	5.6	1.6	2.1	-0.2	1.0	1.5	2.4	1.5	-1.9	1.7	0.0	-0.3	2.3	0.4	1.1	1.2	1.7	1.4	2.3	2.3
Supplements: Vitamin C	0.7	0.8	3.2	0.5	1.2	0.2	0.1	0.8	1.2	0.7	-1.1	0.7	0.2	1.8	1.0	-0.1	0.9	0.5	0.9	0.9	1.5	0.9
Smoking status: Previous	0.7	1.1	2.8	-1.3	-0.0	-0.7	-1.2	-1.6	-1.0	-0.7	0.1	-1.2	-1.2	0.2	-1.2	-1.1	-1.2	-1.0	-1.4	-1.7	-0.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	5.6	1.7	-0.6	0.2	2.4	0.7	0.5	-0.6	1.1	1.9	1.8	-0.4	1.2	2.1	-0.0	1.2	1.0	1.2	0.4	0.7
Eye problems/disorders: Cataract	0.7	0.8	5.3	-0.9	-0.8	-0.6	-0.8	-0.1	-1.0	-1.1	0.6	-0.9	-0.8	-0.9	-0.7	-0.3	-2.3	-0.6	-0.8	-0.5	0.1	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	4.1	-0.4	-1.5	-1.2	0.5	0.5	-1.2	-1.7	2.0	-0.1	1.6	-0.5	-1.0	1.1	-1.5	-0.5	-1.5	0.8	-0.5	-0.6
Lupus	0.6	0.9	2.6	1.3	1.4	-0.5	0.5	0.8	1.5	0.9	-1.0	1.2	0.4	-0.8	1.6	0.3	0.9	0.7	0.8	0.5	1.4	1.0
Systolic Blood Pressure	0.6	3.1	13.4	0.0	3.7	0.7	-2.1	-0.1	2.0	2.7	-3.6	-0.2	-2.5	-0.5	1.2	-2.2	1.7	-1.1	1.1	-0.2	1.2	0.4
Sensitivity / hurt feelings	0.6	1.0	2.5	1.1	1.4	-1.0	-0.3	0.0	1.4	1.5	-1.4	0.8	-0.1	1.4	0.9	-0.3	1.5	0.2	1.6	0.2	0.6	0.7
Supplements: Zinc	0.6	0.6	3.2	-0.7	-1.0	-0.2	-0.1	-0.5	-1.0	-0.8	1.1	-0.5	0.4	1.8	-0.6	0.3	-0.9	0.0	-1.6	-0.4	-0.3	-0.7
Leg fat-free mass (left)	0.6	3.0	9.4	1.1	-2.4	-2.0	3.1	1.1	-0.5	-1.6	2.5	1.6	2.4	-2.0	0.1	2.9	-0.3	2.2	-0.1	1.4	0.1	0.5
Fed-up feelings	0.6	1.1	3.5	0.9	-0.9	-1.0	1.7	1.7	0.3	-0.6	0.8	1.1	1.6	-0.2	0.5	1.3	0.2	0.7	1.1	1.9	0.1	1.6
Relative age voice broke	0.6	0.9	2.6	0.8	-1.1	0.5	1.4	1.6	-0.3	-0.6	1.3	0.9	1.2	1.6	0.1	1.4	-0.3	1.0	0.3	1.3	-0.2	0.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.3	-1.2	-0.5	-0.5	-0.6	-0.9	-1.2	-1.2	0.6	-1.0	-0.4	-0.1	-1.1	-0.6	-0.7	-0.5	-0.9	-1.0	-1.0	-1.5
Leg predicted mass (left)	0.6	3.0	9.8	1.2	-2.4	-2.0	3.1	1.2	-0.5	-1.6	2.5	1.7	2.4	-2.1	0.2	2.9	-0.3	2.3	-0.1	1.4	0.1	0.6
Nervous feelings	0.6	1.2	2.8	1.2	1.4	-0.6	0.3	1.4	1.7	0.5	-1.3	1.1	0.5	-0.8	1.1	0.1	1.2	0.7	1.2	1.2	1.7	1.5
Hearing difficulty/problems with background noise	0.6	1.0	5.0	0.7	-1.3	-2.2	0.7	0.3	-0.2	-1.1	1.2	0.7	1.6	-0.9	0.0	1.6	-0.7	0.5	-0.5	0.6	-1.0	-0.6
Hair/balding pattern: Pattern 2	0.6	0.8	3.3	0.7	1.1	0.4	-0.1	1.8	1.2	1.1	-1.0	0.9	-0.1	1.4	1.0	0.1	0.7	0.7	1.2	1.1	0.4	0.1
Qualifications: None of the above	0.6	1.2	4.2	-1.6	0.6	-0.2	-1.3	-1.5	-0.7	-0.0	-0.5	-1.5	-1.5	0.2	-1.0	-1.9	-1.3	-0.9	-0.5	-2.0	-0.2	-1.1
Diabetes (self-reported)	0.6	1.0	2.4	-1.4	0.2	-1.2	-0.9	-1.3	-0.8	0.2	-0.2	-1.2	-1.3	-1.6	-0.9	-1.3	-0.3	-1.2	-0.8	-1.5	-0.2	-0.3
Weight	0.6	3.0	8.5	0.3	-2.9	-2.4	2.5	0.2	-1.3	-2.5	2.9	0.7	2.1	-2.9	-0.7	2.3	-1.0	1.6	-1.0	0.4	-0.1	0.1
Happiness	0.6	0.7	3.9	0.5	0.1	-1.2	1.0	1.1	-0.0	-0.7	0.5	0.5	0.4	-2.0	0.1	0.8	-0.1	0.3	-0.8	1.3	1.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	-0.9	-0.6	-1.2	-0.9	-0.5	-1.0	-1.1	0.6	-1.0	-0.2	-0.0	-0.9	-0.4	-0.2	-1.2	-1.4	-0.3	-1.1	-0.5
Prospective memory result	0.6	0.7	3.8	-0.1	1.3	-0.7	-1.0	0.0	0.3	1.0	-1.3	-0.2	-2.0	-0.8	0.2	-1.2	-0.6	0.1	0.2	-0.6	0.8	-0.6
Standing height	0.6	6.2	13.7	3.7	0.5	1.5	3.3	2.8	2.5	1.1	-0.4	3.5	1.8	-1.4	3.1	2.8	2.6	3.6	2.5	2.5	1.7	3.2
Length of working week for main job	0.6	0.6	1.8	-1.1	-0.7	1.3	-0.7	-0.8	-0.9	0.2	0.5	-1.0	-0.6	0.3	-1.3	-0.4	0.0	-0.9	-0.9	-0.8	-1.1	0.1
Peak expiratory flow (PEF)	0.6	1.5	4.5	1.8	-1.3	0.6	1.9	1.1	0.5	-0.3	1.0	1.6	1.7	0.4	1.1	2.1	0.0	1.8	-0.1	1.6	0.8	1.1
Arm fat-free mass (right)	0.6	3.3	9.9	0.4	-2.7	-3.1	2.3	0.4	-1.3	-2.8	2.8	0.8	1.9	-3.1	-0.7	2.4	-1.2	1.4	-1.3	0.7	0.1	0.0
Qualifications: College or University degree	0.6	2.0	4.5	1.8	-0.2	1.1	2.1	1.5	1.0	0.4	0.3	1.7	1.6	-1.6	1.4	1.9	2.1	1.2	1.1	1.6	0.2	2.1
Arm predicted mass (right)	0.6	3.2	10.0	0.1	-2.7	-2.9	2.1	0.2	-1.5	-2.9	2.8	0.5	1.7	-3.2	-0.9	2.1	-1.4	1.2	-1.5	0.5	-0.0	-0.2
Number of full sisters	0.6	0.7	2.9	-0.8	-0.7	-0.1	-0.5	-0.8	-0.9	-0.7	0.7	-0.8	0.1	-1.7	-1.0	-0.1	-1.3	-1.2	-0.9	-0.4	-1.0	-0.7
Had major operations	0.6	0.7	1.6	0.7	-0.1	0.6	1.2	1.1	0.6	0.4	-0.1	0.9	0.4	1.2	0.7	0.7	1.0	0.4	1.3	1.2	-0.3	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.2	-1.2	0.2	0.1	-1.1	-0.3	-0.7	-0.3	-0.2	-1.1	-1.2	0.8	-1.3	-0.9	-0.1	-1.3	-0.1	-0.7	-1.4	-1.5
Medication: Aspirin	0.6	0.8	2.4	-0.2	1.3	1.5	-0.6	-0.1	0.8	1.6	-1.4	-0.2	-0.9	-0.5	0.3	-1.0	1.0	-0.1	-0.0	-0.0	1.5	0.7
Illnesses of siblings: Diabetes	0.6	0.7	2.7	0.4	1.3	1.6	-0.4	-0.7	1.0	1.6	-1.2	0.1	-0.5	-0.2	0.9	-0.6	0.3	0.1	0.3	-0.8	1.6	0.3
Leg fat-free mass (right)	0.6	3.0	9.4	1.1	-2.6	-2.1	3.1	1.0	-0.6	-1.7	2.6	1.6	2.4	-2.2	0.0	2.8	-0.3	2.1	-0.1	1.4	0.0	0.7
Friendships satisfaction	0.6	0.7	5.4	-0.7	-0.3	-1.4	-0.4	-0.1	-0.7	-0.7	0.5	-0.6	-0.0	-2.3	-0.9	0.1	-0.4	-1.2	-1.2	-0.1	-0.8	-0.5
Medication: Aspirin	0.6	0.8	3.2	-0.4	1.4	1.2	-0.6	-0.3	0.7	1.5	-1.4	-0.3	-1.0	-0.9	0.1	-1.1	0.8	-0.2	-0.4	-0.2	1.8	0.6
Leg predicted mass (right)	0.6	3.0	8.8	1.0	-2.6	-2.1	3.0	0.9	-0.7	-1.8	2.6	1.5	2.3	-2.4	-0.0	2.8	-0.4	2.0	-0.2	1.2	-0.0	0.6
Average weekly champagne plus white wine intake	0.6	0.9	2.5	0.2	1.1	1.3	-1.0	-0.2	0.8	1.5	-1.6	-0.1	-1.4	-0.3	0.5	-1.4	0.2	-0.3	1.5	-0.8	0.5	0.2
Guilty feelings	0.6	0.9	2.9	0.8	1.3	-0.2	0.5	0.6	1.3	1.2	-1.0	0.7	0.2	1.5	0.7	0.1	1.1	0.3	1.1	0.8	1.3	1.7
Ever taken oral contraceptive pill	0.6	0.7	1.8	0.6	1.2	0.1	-0.1	0.6	1.1	0.9	-1.0	0.7	-0.0	1.2	1.1	-0.1	0.9	0.1	0.8	1.0	1.4	0.7
Arm fat-free mass (left)	0.6	3.1	8.9	0.1	-2.7	-3.0	2.1	0.1	-1.4	-2.7	2.8	0.6	1.8	-3.0	-0.9	2.1	-1.5	1.2	-1.3	0.3	-0.1	-0.2
Fractured/broken bones in last 5 years	0.6	0.8	2.2	-0.3	-1.5	-1.0	0.6	-0.2	-1.1	-1.5	1.4	-0.1	0.4	-0.1	-0.9	0.9	-1.4	-0.1	-0.9	0.3	-0.7	-1.0
Commuting to job workplace: Cycle	0.6	0.7	4.3	-0.5	-0.9	2.1	-0.2	-0.4	-1.0	-0.3	0.8	-0.8	0.1	1.5	-0.8	-0.5	-1.4	-0.2	-0.7	-0.3	-0.7	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	3.1	-0.8	1.4	0.8	-1.0	-0.3	0.2	1.0	-1.3	-0.7	-1.8	0.1	-0.2	-1.6	0.4	-0.5	-0.3	-0.9	0.6	-0.6
Arm predicted mass (left)	0.6	3.3	10.8	0.0	-2.8	-3.1	2.0	0.1	-1.5	-3.0	2.9	0.4	1.7	-3.3	-1.0	2.0	-1.6	1.1	-1.3	0.3	-0.2	-0.3
Bipolar Disorder (2018)	0.5	0.8	2.0	-1.2	-0.4	0.2	-0.9	-1.4	-0.9	0.2	0.1	-1.2	-0.8	-1.3	-1.2	-1.0	-0.1	-0.9	-1.2	-1.3	-0.6	-0.7
Crohns Disease (2017)	0.5	1.1	3.1	1.2	1.2	0.7	0.9	0.7	1.4	1.8	-1.1	1.3	-0.1	1.0	1.1	0.3	1.4	0.8	1.6	0.8	-0.7	0.8
Primary Biliary Cirrhosis	0.5	0.8	2.8	0.9	-0.5	0.0	1.7	0.9	0.4	0.8	0.4	0.9	0.9	0.6	0.6	0.9	1.0	0.7	1.0	1.2	-0.4	1.5
Ulcerative Colitis	0.5	0.8	3.2	0.4	-1.3	-0.0	1.8	0.7	-0.2	-1.0	1.1	0.8	1.4	0.5	-0.1	1.2	-0.7	0.8	1.1	1.0	-0.1	0.5
Hand grip strength (left)	0.5	1.4	3.0	1.4	-0.1	1.1	1.2	1.7	1.2	0.8	-0.2	1.6	1.2	0.2	1.1	1.3	0.5	1.0	1.3	1.7	1.7	1.4
Stomach or abdominal pain in last month	0.5	0.6	2.8	-0.5	-0.5	1.7	-0.1	-0.4	-0.8	-0.4	0.6	-0.6	-0.6	-1.5	-0.8	-0.0	-0.9	-0.3	-1.3	-0.6	0.8	-0.4
High blood pressure (mother)	0.5	0.7	2.6	1.1	0.3	-0.1	0.5	0.6	1.4	1.3	-0.9	1.3	0.6	-0.1	1.1	0.9	0.6	0.0	1.6	1.0	0.5	0.4
Number of incorrect matches in round	0.5	0.8	2.6	-0.5	0.7	-0.4	-1.6	-0.4	0.2	0.6	-1.1	-0.7	-1.6	-1.5	-0.4	-1.5	-0.1	-0.5	0.6	-0.8	-0.8	-0.4
Past tobacco smoking	0.5	1.0	3.0	1.0	-0.0	1.5	0.7	1.4	0.8	0.8	-0.2	0.8	0.8	0.5	0.9	0.7	1.7	0.5	1.7	1.6	-0.8	0.7
Had other major operations	0.5	0.6	4.1	0.8	-0.1	0.1	0.5	1.2	0.3	0.2	0.0	0.6	0.2	2.0	0.6	0.2	0.7	0.8	1.4	0.6	-0.1	0.8
Financial difficulties in last 2 years	0.5	0.6	5.8	0.2	0.6	0.9	-0.2	0.6	0.5	1.4	-0.6	0.2	-0.1	2.4	0.2	-0.2	0.8	-0.7	0.4	0.7	0.6	0.6
Depression (self-reported)	0.5	0.6	2.9	0.6	0.3	-0.2	0.3	1.7	0.5	-0.4	0.0	0.6	1.0	0.9	0.4	0.4	-0.2	0.1	-0.0	1.6	1.7	0.3
Medication: Lansoprazole	0.5	0.5	2.8	0.6	0.4	0.4	0.7	1.4	0.6	0.4	-0.3	0.7	0.2	0.3	0.4	0.5	0.0	1.2	0.7	1.7	0.5	0.7
Arm fat mass (right)	0.5	2.1	6.4	-0.4	-2.5	-2.2	1.5	-0.5	-1.5	-2.4	2.5	-0.0	1.4	-2.1	-1.2	1.4	-1.4	0.8	-1.1	-0.3	-0.3	-0.6
Hair/balding pattern: Pattern 4	0.5	1.3	4.2	-1.0	-2.0	-0.2	0.3	-0.9	-1.7	-1.6	2.0	-0.8	1.4	-0.0	-1.6	0.6	-1.0	-0.6	-1.1	-0.3	-1.4	-0.9
Forced vital capacity (FVC), Best measure	0.5	1.7	4.5	1.9	-0.7	0.4	2.0	1.2	0.6	-0.4	0.8	1.8	1.4	0.4	1.4	2.1	-0.3	2.1	0.6	1.6	1.2	1.3
Body fat percentage	0.5	1.8	6.1	-0.6	-2.4	-1.4	0.9	-0.9	-1.6	-2.5	2.2	-0.5	1.2	-2.1	-1.3	0.8	-1.6	0.3	-1.4	-0.7	-0.1	-0.7
Whole body fat mass	0.5	2.2	7.3	-0.1	-2.5	-2.0	1.6	-0.4	-1.3	-2.5	2.4	0.1	1.5	-2.7	-0.9	1.5	-1.5	0.8	-1.2	-0.1	0.2	-0.4
Comparative height size at age 10	0.5	2.5	7.3	2.1	0.9	-0.2	2.0	1.3	1.7	0.6	-0.4	2.0	1.3	-1.9	1.9	1.6	2.7	1.9	1.6	1.2	0.2	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.7	-1.0	-0.1	-0.7	-0.9	-0.9	-0.7	-0.5	0.2	-0.8	-0.9	1.1	-0.8	-0.7	-0.9	-0.2	-1.3	-0.9	-0.0	-1.2
Mineral and other dietary supplements	0.5	0.7	2.4	0.9	-0.7	0.7	1.5	0.7	0.3	0.3	0.7	1.0	1.5	0.1	0.6	1.3	0.2	0.4	0.5	1.1	0.3	1.2
Arm fat mass (left)	0.5	2.0	6.2	-0.2	-2.5	-2.0	1.6	-0.2	-1.4	-2.3	2.5	0.1	1.5	-1.8	-1.0	1.5	-1.3	1.0	-1.2	0.0	0.1	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.6	-0.6	-0.5	-1.5	-0.7	-0.3	-0.8	-0.5	0.4	-0.7	-0.7	-0.4	-0.6	-0.2	-0.1	-0.9	-1.0	-0.5	-1.6	-1.4
Medication: Paracetamol	0.5	0.7	1.7	-1.2	-0.1	-1.2	-0.9	-1.0	-0.8	0.4	-0.1	-1.2	-1.3	-0.5	-1.0	-1.3	-0.1	-1.2	-0.2	-0.9	-0.6	-0.0
Alcohol drinker status: Never	0.5	0.6	2.5	0.1	1.4	-1.4	-0.3	0.1	0.9	0.7	-1.6	0.2	-1.2	-0.7	0.7	-0.7	0.3	-0.0	0.5	-0.4	0.2	-0.2
Basal metabolic rate	0.5	2.8	7.1	0.8	-2.4	-2.5	2.6	0.7	-0.8	-2.1	2.5	1.2	2.0	-2.7	-0.2	2.5	-0.7	1.8	-0.6	1.0	0.1	0.3
Risk taking	0.5	0.7	3.8	-0.3	-0.5	-2.0	0.5	0.1	-0.7	-1.4	0.7	-0.1	0.0	-1.6	-0.6	0.3	-1.5	-0.4	-0.4	0.1	0.3	-0.3
Age started oral contraceptive pill	0.5	0.6	1.8	0.5	1.0	0.0	0.6	0.1	0.8	1.2	-0.6	0.6	0.2	-1.3	0.7	0.3	1.1	0.8	-0.0	0.5	1.4	0.9
Supplements: Calcium	0.5	0.6	2.9	0.5	0.6	-1.3	0.3	0.6	0.9	0.7	-0.9	0.5	-0.2	0.3	1.0	0.0	1.7	0.6	0.3	0.3	0.5	1.3
Depression (Nagel 2018)	0.4	0.5	1.4	0.4	0.9	-0.8	-0.1	1.0	0.9	0.8	-1.0	0.3	-0.5	0.9	0.4	-0.5	0.5	0.2	1.1	0.4	1.2	1.1
Breast Cancer	0.4	1.0	2.9	-0.3	-1.6	1.7	0.2	-0.8	-1.3	-0.3	1.6	-0.4	0.8	0.1	-1.0	1.0	-0.5	-0.1	-1.0	-0.9	-1.7	-0.9
Ovarian Cancer	0.4	0.6	3.6	0.1	-1.1	-1.9	0.5	0.6	-0.4	-1.7	0.9	0.3	0.6	-0.9	0.0	0.7	-0.2	0.1	-0.2	0.5	-0.0	0.3
Fasting Glucose	0.4	0.5	2.9	0.4	-0.4	-0.7	0.3	0.6	-0.1	-0.5	0.8	0.3	1.1	-1.7	0.2	1.0	0.1	-0.2	-0.4	0.5	0.3	1.0
Height	0.4	7.0	17.0	3.6	1.8	1.5	2.7	2.1	3.4	2.7	-1.6	3.3	1.6	-1.6	3.6	1.8	3.7	3.1	2.9	1.8	2.2	4.1
Smoking Status	0.4	1.0	5.4	-1.2	-0.6	-0.7	-0.4	-0.8	-1.2	-0.9	0.8	-0.9	-0.2	-0.5	-1.4	-0.6	-2.3	-0.6	-1.4	-1.0	0.5	-0.9
Allergy or Eczema	0.4	0.9	2.2	0.7	1.1	1.4	0.4	0.8	1.2	1.2	-1.0	0.8	0.1	0.4	1.1	-0.1	1.4	0.6	1.0	0.8	1.5	1.4
Hypothyroidism (self reported)	0.4	0.9	4.4	-1.1	-0.5	0.3	-0.5	-2.1	-0.9	-0.3	0.4	-1.0	-0.4	-1.1	-1.2	-0.7	-0.8	-0.5	-1.1	-1.9	-0.4	-0.6
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.8	-1.1	-0.3	-1.6	-0.5	-1.1	-0.9	-0.4	0.4	-1.0	-0.6	-1.7	-0.8	-0.8	-0.3	-1.3	-1.3	-1.0	0.1	-0.3
Average weekly spirits intake	0.4	0.5	1.8	-1.0	-0.5	0.4	-0.6	-0.1	-0.7	-0.5	0.3	-0.9	-0.2	1.3	-1.1	-0.9	-0.6	-1.3	0.0	-0.0	-0.2	-0.5
Ever had hysterectomy (womb removed)	0.4	0.4	1.4	-0.6	-0.6	-1.1	-0.3	-0.7	-0.8	-0.7	0.6	-0.5	0.0	-0.7	-0.8	-0.0	-0.6	-0.8	-1.2	-0.5	-0.5	-0.5
Impedance of leg (right)	0.4	1.7	5.7	0.4	2.3	1.9	-1.7	-0.1	1.4	1.5	-2.4	-0.3	-1.5	1.2	1.2	-1.6	0.7	-1.3	1.1	-0.6	1.1	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.8	0.6	0.6	-0.8	0.4	1.2	0.6	0.2	-0.5	0.6	-0.2	1.2	0.5	-0.0	0.5	0.4	1.3	0.9	0.5	0.8
Taking other prescription medications	0.4	0.6	1.9	-1.2	0.2	0.5	-0.8	-0.8	-0.6	0.3	-0.2	-0.9	-0.8	0.7	-0.8	-1.4	-0.6	-1.1	-0.4	-1.1	-0.5	-0.8
Medication: Atenolol	0.4	0.5	1.7	-0.7	-1.3	-0.6	-0.0	-0.8	-1.0	-0.8	0.9	-0.5	-0.1	-0.6	-0.7	0.1	-0.9	0.6	-0.7	-0.7	-0.6	-1.1
Chronic bronchitis/emphysema (father)	0.4	0.4	2.3	-0.3	0.0	-0.4	-0.5	-1.2	0.1	0.8	-0.5	-0.4	-0.9	-0.7	-0.5	-0.4	-0.1	-0.2	-0.7	-1.5	0.8	-0.2
Trunk fat mass	0.4	1.6	5.3	0.2	-2.2	-1.4	1.7	-0.2	-1.0	-2.1	2.1	0.3	1.6	-2.3	-0.5	1.5	-1.1	1.1	-0.7	-0.0	0.2	0.0
Waist circumference	0.4	1.4	3.2	-1.2	-1.7	-1.3	0.5	-1.4	-1.7	-1.8	1.7	-1.0	0.4	-1.5	-1.7	0.1	-1.1	-0.4	-1.3	-1.1	-0.7	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.6	-0.3	-1.1	-0.2	1.1	0.8	-0.7	-0.6	1.3	0.1	1.0	-0.4	-0.3	0.7	-0.2	0.0	-0.4	1.0	-0.5	0.1
Mouth/teeth dental problems	0.4	0.7	2.8	0.9	0.8	0.5	0.5	0.3	1.0	1.4	-0.9	0.8	-0.7	0.1	0.9	0.2	1.4	1.0	1.7	-0.1	-0.2	0.3
Heart attack	0.4	0.5	3.3	0.3	0.9	0.7	0.1	0.2	0.8	1.5	-1.0	0.3	-0.4	-0.4	0.9	-0.4	0.1	0.4	-0.2	0.1	1.8	0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.1	-0.8	-0.4	-0.8	-0.3	-1.4	-0.9	-0.6	0.6	-0.9	-0.1	-0.6	-0.8	-0.5	-0.0	-0.1	-1.4	-1.2	-0.4	-0.7
Hip circumference	0.4	1.7	5.0	-0.4	-2.2	-2.1	1.0	-0.3	-1.5	-2.2	2.2	-0.2	1.1	-2.1	-1.1	1.0	-0.9	0.6	-1.3	-0.3	-0.6	-0.6
Trunk predicted mass	0.4	2.1	7.0	0.8	-1.6	-2.5	2.2	1.1	-0.4	-1.6	1.8	1.3	1.5	-2.6	0.2	2.1	-0.2	1.6	-0.5	1.2	0.2	0.5
Birth weight of first child	0.4	0.7	2.8	-1.0	-0.8	-0.8	0.1	-0.9	-1.1	-1.7	0.9	-0.8	-0.3	-1.1	-1.0	-0.1	-0.0	-0.3	-0.3	-0.9	-1.4	-0.3
Emphysema/chronic bronchitis	0.4	0.4	1.3	-0.3	1.1	0.0	-0.8	-0.3	0.4	1.1	-0.9	-0.5	-0.7	-0.7	0.1	-0.7	0.8	-0.8	-0.5	-0.3	0.2	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.1	-0.4	1.0	1.4	-0.5	-0.5	0.4	1.0	-1.0	-0.4	-0.9	0.2	-0.0	-0.8	0.2	-1.1	0.7	-0.2	-0.2	0.3
Overall health rating	0.4	0.9	2.3	-1.5	-0.6	-0.6	-0.6	-0.6	-1.3	-1.0	0.6	-1.4	-0.8	0.0	-1.5	-1.0	-1.3	-0.9	-1.3	-0.9	-0.1	-0.9
Leg pain on walking	0.4	0.5	2.8	0.4	0.6	-1.7	0.2	1.0	0.5	0.2	-0.2	0.7	0.0	-0.1	0.7	0.6	1.3	0.9	0.3	0.6	-0.5	0.3
Whole body fat-free mass	0.4	2.4	6.8	0.9	-2.0	-2.5	2.5	1.0	-0.6	-1.8	2.2	1.3	1.8	-2.6	0.1	2.4	-0.3	1.8	-0.4	1.2	0.2	0.4
Commuting to job workplace: Walk	0.4	0.4	1.5	0.0	0.8	-0.3	-0.2	0.1	0.6	0.8	-0.9	-0.0	-0.4	1.2	0.6	-0.8	0.6	0.9	0.5	-0.1	0.8	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.5	1.3	0.2	-0.1	1.0	1.0	0.9	0.1	-0.1	1.3	0.5	0.9	1.3	1.0	0.3	1.9	0.9	1.1	0.5	0.9
Whole body water mass	0.4	2.5	6.5	0.8	-2.2	-2.3	2.5	1.0	-0.7	-1.9	2.3	1.3	1.9	-2.5	-0.1	2.4	-0.4	1.7	-0.5	1.1	0.1	0.4
Commuting to job workplace: Public transport	0.4	0.5	5.3	0.1	0.5	2.3	0.1	-0.1	0.3	0.9	-0.6	-0.1	-0.7	-0.1	0.2	-0.6	1.1	0.2	0.5	-0.5	0.2	1.1
Number of operations (self-reported)	0.4	0.6	3.4	-0.8	0.1	-1.9	-0.7	-0.2	-0.3	0.0	-0.5	-0.6	-1.2	1.8	-0.3	-1.1	0.0	-0.3	0.0	-0.5	0.0	-0.4
Diastolic blood pressure, automated reading	0.4	1.2	3.3	0.9	1.8	-0.8	0.1	1.2	1.8	1.3	-1.7	1.1	-0.1	-0.5	1.3	0.3	1.4	0.2	1.2	1.1	0.8	1.1
Age at First Birth	0.3	0.5	3.5	-0.1	0.5	-1.9	-0.8	-0.1	0.4	-0.1	-0.6	0.1	-0.4	-1.6	0.3	-0.3	-0.4	0.4	0.0	-0.6	0.6	-0.7
HDL Cholesterol	0.3	0.5	1.8	0.0	1.3	-0.4	-0.6	-0.1	0.8	1.1	-1.3	0.0	-0.7	0.2	0.3	-0.8	1.0	0.3	1.0	-0.3	0.7	0.5
Rheumatoid Arthritis	0.3	0.4	1.4	0.1	-0.8	-0.2	0.7	-0.3	-0.5	-0.9	1.0	0.0	1.1	-0.0	-0.4	0.5	-1.2	0.7	-0.1	-0.1	-0.3	-0.2
Waist Hip Ratio (WHR)	0.3	1.3	6.5	-0.5	1.4	2.5	-0.8	-0.8	0.4	1.1	-1.5	-0.7	-1.6	1.7	-0.1	-1.4	1.4	-1.3	1.0	-0.6	-0.1	0.4
Neuroticism	0.3	0.8	2.5	0.9	1.3	-0.2	-0.2	1.0	1.6	0.9	-1.5	0.8	-0.0	0.4	0.8	-0.2	0.7	0.7	1.0	0.8	1.1	1.0
Angina	0.3	0.4	2.6	0.0	0.6	-1.0	-0.1	-0.0	0.5	1.0	-0.7	0.1	-0.4	0.6	0.8	-0.4	-0.6	0.2	0.2	-0.4	1.6	0.2
Vitamin and mineral supplements	0.3	0.4	1.7	-0.1	-1.2	-1.0	0.8	-0.4	-0.5	-0.6	1.0	0.1	0.9	-1.3	-0.3	0.6	-0.4	-0.3	0.2	-0.3	-0.7	-0.1
Pack years adult smoking proportion	0.3	0.4	1.4	-0.9	-0.7	0.1	0.5	-0.8	-0.8	-0.7	0.8	-0.6	0.2	-1.2	-0.6	-0.1	-0.4	-1.1	-0.1	-0.4	-0.9	0.1
Hand grip strength (right)	0.3	0.8	2.4	0.3	-1.5	-0.1	1.3	0.7	-0.4	-1.2	1.4	0.5	1.5	-1.0	-0.3	1.3	-0.3	0.2	-0.4	0.9	0.6	0.6
Qualifications: CSEs or equivalent	0.3	0.3	1.1	-0.6	-0.3	0.3	-0.7	-0.8	-0.7	-0.3	0.4	-0.8	-0.3	0.1	-0.8	-0.5	-0.9	-1.0	-0.2	-0.8	-0.5	-0.4
Impedance of leg (left)	0.3	1.5	4.3	-0.1	1.8	1.6	-2.0	-0.7	0.9	0.9	-2.1	-0.8	-1.7	0.7	0.6	-2.0	0.3	-1.7	0.8	-1.0	0.9	0.5
Allergy	0.3	0.6	1.8	0.3	-1.3	-1.1	0.1	0.3	-0.8	-1.2	1.2	0.1	0.7	-0.7	-0.4	1.0	-0.8	0.5	-0.4	0.1	-1.1	-1.0
Pain all over the body in last month	0.3	0.3	0.9	0.5	0.2	0.7	0.8	0.6	0.3	0.4	0.0	0.6	0.2	1.0	0.4	0.3	0.6	0.4	0.7	0.6	0.1	0.8
Illnesses of siblings	0.3	0.5	1.2	0.4	-1.1	0.1	1.0	0.5	-0.2	-1.1	0.8	0.6	0.9	0.3	0.1	1.0	0.5	0.3	0.5	0.8	-1.1	0.6
Arm fat percentage (right)	0.3	1.1	3.7	-0.2	-1.9	-1.2	1.3	-0.3	-1.0	-1.7	1.9	0.1	1.4	-1.4	-0.8	1.1	-0.9	0.6	-0.6	-0.1	-0.2	-0.4
Trunk fat-free mass	0.3	2.0	6.6	0.9	-1.5	-2.5	2.2	1.1	-0.3	-1.6	1.7	1.3	1.4	-2.6	0.2	2.1	-0.2	1.7	-0.4	1.1	0.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.5	0.5	-0.7	-0.6	0.7	0.8	-0.1	-0.8	0.9	0.7	0.8	-0.3	0.1	1.2	-1.1	0.8	-0.2	0.8	0.5	0.1
Hair/balding pattern: Pattern 3	0.3	0.5	1.2	-0.6	-0.2	-0.6	-0.5	-0.8	-0.8	-0.9	0.3	-0.8	-0.5	0.0	-0.6	-0.4	-0.9	-1.1	-0.7	-0.8	-0.9	-0.8
Number of live births	0.3	0.4	1.3	-0.0	1.0	-0.9	-0.4	0.3	0.5	1.0	-1.0	-0.1	-0.7	1.1	0.5	-0.7	0.1	-0.5	0.6	0.4	1.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.2	0.5	-0.3	-1.0	0.3	1.0	0.2	-0.2	0.2	0.5	0.7	-0.3	0.5	0.4	0.3	0.7	-0.1	1.1	1.5	0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.2	-0.5	0.1	1.0	-0.3	-0.1	-0.5	0.2	0.2	-0.4	-0.3	1.2	-0.7	-0.3	-0.7	0.0	-1.5	-0.2	0.4	-0.4
Headache pain in last month	0.3	0.5	2.6	-0.3	-1.6	0.6	0.7	-0.4	-0.8	-0.9	1.2	-0.1	0.7	0.2	-0.7	0.6	-0.9	-0.2	-0.2	-0.4	-0.9	-0.4
Glaucoma (self-reported)	0.3	0.3	2.0	-0.5	-0.7	0.8	-0.0	-0.6	-0.5	-0.4	0.4	-0.4	0.3	0.6	-0.9	0.1	0.3	-0.1	-1.4	-0.5	-0.1	0.1
Medication: Amlodipine	0.3	0.4	3.2	-0.2	0.5	-1.8	-0.6	-0.2	0.0	-0.1	-0.3	-0.2	-0.3	-0.9	-0.3	-0.2	-1.1	-0.5	-0.5	-0.2	1.0	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.7	0.7	-0.4	-0.2	1.0	0.7	0.4	-0.3	0.3	0.8	1.1	-0.6	0.2	0.8	-0.0	-0.0	-0.1	1.0	1.3	0.8
Wheeze or whistling in the chest in last year	0.3	0.5	1.5	-1.0	1.2	0.3	-0.4	-0.6	0.1	0.7	-0.8	-0.8	-0.8	-0.3	-0.7	-1.2	0.4	-0.9	-0.2	-0.1	0.8	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	0.6	-0.6	-1.4	0.6	-0.5	-0.0	-0.8	0.5	0.4	0.8	-0.8	0.3	0.8	-0.7	0.4	-0.5	-0.0	0.8	0.1
Neck or shoulder pain in last month	0.3	0.5	8.1	-0.3	0.0	-2.9	-0.5	-0.2	0.0	-0.1	-0.1	-0.2	-0.2	-0.9	-0.0	-0.0	0.1	-0.2	-0.2	-0.2	-0.2	-0.0
Mean time to correctly identify matches	0.3	0.6	2.3	-0.5	1.2	-0.2	-0.7	-0.6	0.3	1.4	-1.1	-0.7	-0.8	0.7	-0.5	-1.5	0.3	-0.1	0.2	-0.9	0.2	-0.2
Arm fat percentage (left)	0.3	1.4	4.7	-0.3	-2.1	-1.1	1.3	-0.3	-1.3	-1.9	2.2	-0.1	1.4	-1.3	-1.0	1.2	-1.1	0.7	-1.0	-0.1	-0.1	-0.5
Average weekly red wine intake	0.3	0.4	1.8	0.4	0.4	-1.2	-0.4	-0.2	0.5	0.9	-0.6	0.1	-0.1	-1.3	0.4	0.1	1.3	0.1	-0.1	0.0	-0.6	0.3
Mood swings	0.3	0.5	2.8	0.0	0.7	-0.5	0.2	0.6	1.0	0.5	-1.1	0.3	-0.2	0.0	0.4	-0.7	0.6	-0.8	1.7	0.5	0.8	1.0
Qualifications: nursing, teaching	0.3	0.5	3.2	0.6	-0.3	-0.7	0.7	0.2	0.3	0.2	0.3	0.6	0.9	-0.9	0.3	1.0	1.4	0.5	0.6	0.3	-1.8	0.4
Financial situation satisfaction	0.3	0.4	1.0	-0.4	-0.9	-0.8	0.5	0.3	-0.9	-0.9	1.0	-0.5	0.1	0.3	-1.0	0.2	-0.4	0.3	-0.9	0.6	0.6	0.4
Eye problems/disorders: Glaucoma	0.3	0.4	1.9	-0.6	-0.7	1.3	-0.2	-0.9	-0.6	-0.2	0.6	-0.5	0.3	-0.2	-0.9	0.1	0.0	-0.3	-1.4	-0.9	-0.2	-0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.6	-0.4	0.7	-0.6	-1.0	-0.1	-0.1	0.1	-0.7	-0.6	-1.3	0.5	-0.2	-1.0	-0.6	-0.2	-0.2	-0.5	0.2	-0.6
Illnesses of father: High blood pressure	0.3	0.3	1.9	-0.2	-0.5	1.3	-0.1	0.6	-0.3	-0.2	0.4	0.1	0.3	1.4	-0.3	0.4	-0.3	-0.1	-0.4	0.7	-0.5	-0.6
Pain experienced in last month	0.3	0.4	2.2	0.5	0.6	1.5	0.5	0.5	0.6	0.5	-0.3	0.5	0.9	0.2	0.4	0.3	0.2	0.1	0.3	0.9	0.9	1.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.5	0.1	0.8	0.4	-0.1	0.1	0.6	1.2	-0.9	0.1	-0.5	-0.3	0.7	-0.5	-0.1	0.4	-0.1	-0.1	1.6	-0.1
Depressed Affect (Nagel 2018)	0.2	0.3	1.8	0.2	-0.0	-1.4	0.6	1.0	0.5	-0.1	-0.2	0.4	0.6	-0.1	-0.1	-0.0	-0.2	-0.1	0.8	0.8	0.7	1.1
Alzheimer’s Disease (including proxy)	0.2	0.2	0.8	-0.2	0.8	0.2	-0.4	-0.0	0.4	0.3	-0.8	-0.2	-0.8	0.3	0.3	-0.9	0.5	-0.2	0.7	-0.5	0.1	-0.5
Neuroticism (2016)	0.2	0.3	1.6	0.7	-0.3	-1.3	0.5	0.5	0.3	-0.3	0.0	0.6	0.2	-1.1	0.3	0.7	0.1	0.3	0.7	0.1	0.3	0.2
Triglycerides	0.2	0.4	1.6	-0.2	-0.8	-0.9	0.1	0.2	-0.6	-1.0	0.8	0.0	0.1	0.6	-0.3	0.4	-1.3	-0.1	-0.3	-0.3	-0.6	-1.1
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.1	0.1	-0.3	-0.4	0.4	0.5	0.2	0.0	0.1	0.1	0.6	-0.7	0.2	-0.0	0.9	-0.6	1.1	0.5	-0.8	0.8
Blood Eosinophil Count	0.2	1.4	3.0	1.4	0.5	0.6	1.0	1.4	1.6	1.2	-0.9	1.6	0.6	0.9	1.4	1.0	1.0	1.7	1.7	1.4	0.8	0.9
Blood Platelet Count	0.2	2.0	9.4	-1.4	1.8	0.9	-1.9	-0.6	0.0	0.5	-1.5	-1.3	-1.7	3.1	-0.5	-2.0	1.3	-2.1	-0.4	-0.1	-1.4	-0.2
Blood White Count	0.2	1.7	4.9	1.8	-0.6	0.2	1.8	1.4	1.1	0.1	0.4	2.0	2.1	0.7	1.2	2.2	0.5	1.3	0.8	1.9	0.8	1.0
Lung FVC	0.2	0.9	5.8	0.0	-1.0	-0.6	0.4	-0.0	-0.8	-0.9	1.4	0.1	1.1	2.4	-0.5	0.6	-2.1	0.5	-1.1	0.4	-0.1	-0.5
Hair Pigment	0.2	6.4	14.1	-3.3	0.1	-0.4	-3.8	-3.1	-2.6	-0.9	0.1	-3.7	-3.3	0.3	-3.0	-3.0	-1.4	-3.1	-2.8	-3.6	-2.2	-2.5
Medication: Metformin	0.2	0.3	0.8	0.5	0.3	-0.4	0.5	0.4	0.6	0.5	-0.3	0.7	0.2	-0.4	0.8	0.5	0.5	0.0	0.1	0.2	0.9	0.7
Trunk fat percentage	0.2	0.9	3.3	0.0	-1.8	-0.7	1.1	-0.5	-0.8	-1.8	1.6	-0.0	1.2	-1.5	-0.6	0.9	-1.0	0.7	-0.5	-0.4	0.2	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.5	0.2	0.7	1.0	0.4	0.3	0.7	0.7	-0.7	0.4	-0.2	1.1	0.7	-0.3	1.0	0.0	1.2	0.3	0.5	1.1
Alcohol usually taken with meals	0.2	0.3	1.6	0.8	-0.2	-0.2	-0.1	0.3	0.6	0.4	-0.5	0.4	0.2	-1.3	0.6	-0.1	0.2	-0.3	1.1	0.6	-0.9	0.2
Had menopause	0.2	0.2	1.3	0.3	-0.2	-0.7	-0.0	0.3	-0.1	-0.5	0.3	0.2	0.4	-0.2	-0.2	0.2	-0.7	1.2	0.2	0.2	-0.3	-0.8
Asthma	0.2	0.3	1.6	-0.6	0.7	0.1	-0.7	-0.9	0.1	0.4	-0.7	-0.5	-0.4	0.6	-0.2	-1.0	0.1	-1.2	-0.4	-0.5	0.2	-0.0
Medication: Cholesterol lowering	0.2	0.4	5.3	0.3	-0.0	-1.0	-0.2	-0.2	0.2	0.4	-0.2	0.2	0.0	-2.3	0.5	-0.1	-0.2	0.2	0.4	-0.3	-0.1	-0.0
Lung cancer (father)	0.2	0.2	1.7	-0.5	-0.6	-0.7	-0.1	0.2	-0.4	-0.4	0.4	-0.2	-0.1	0.5	-0.4	0.2	0.0	-0.3	0.3	-0.1	-1.3	-0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.6	0.6	0.7	0.8	-0.1	0.0	0.6	0.9	-0.6	0.4	-0.2	1.3	0.6	-0.0	0.2	-0.2	-0.2	0.5	1.1	0.7
Blood clot in the leg (DVT)	0.2	0.2	1.6	-0.2	-0.0	-0.4	0.4	0.1	-0.2	-0.2	0.3	-0.1	0.1	-1.2	-0.2	0.3	0.3	0.2	-1.1	0.4	0.5	0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.1	-0.6	-0.7	0.4	0.4	-1.1	-0.5	0.0	0.5	-0.3	0.3	-1.4	-0.7	-0.1	0.0	-0.1	-0.6	-1.0	-0.5	0.0
High blood pressure (siblings)	0.2	0.3	1.7	0.2	0.9	-0.3	-0.3	0.3	0.6	1.3	-0.7	0.3	-0.2	0.6	0.3	-0.2	-0.4	-0.1	0.0	-0.2	1.3	0.3
Health satisfaction	0.2	0.2	1.1	-0.4	-0.1	-0.9	0.0	0.1	-0.3	-0.5	0.1	-0.3	-0.7	-1.1	-0.5	-0.1	0.3	-0.3	-0.0	-0.1	-0.8	-0.0
Angina (self-reported)	0.2	0.3	1.9	-0.2	0.4	-0.9	-0.2	-0.2	0.3	0.9	-0.5	-0.1	-0.4	0.3	0.5	-0.5	-0.5	0.1	-0.2	-0.6	1.4	0.1
Migraine (self-reported)	0.2	0.3	0.9	-0.7	-0.1	0.5	-0.1	-0.5	-0.4	-0.1	0.0	-0.4	-0.7	0.7	-0.5	-0.7	-0.5	0.2	0.2	-1.0	-0.6	-0.7
Heart disease (mother)	0.2	0.2	0.6	0.5	-0.5	0.5	0.7	0.1	0.2	0.1	0.3	0.4	0.5	0.7	0.2	0.8	-0.7	-0.3	0.6	0.2	-0.0	0.0
Chest pain or discomfort	0.2	0.3	2.0	-0.0	0.7	0.1	-0.2	0.3	0.6	0.7	-0.8	0.1	-0.4	1.0	0.5	-0.2	0.1	0.6	-0.1	0.2	1.4	0.3
Knee pain experienced in last month	0.2	0.4	1.7	-0.4	-0.8	-1.3	-0.0	-0.2	-0.7	-1.0	0.6	-0.3	-0.3	-0.1	-0.5	-0.1	-0.6	-0.6	0.1	-0.4	-1.1	-0.6
Diabetes diagnosed by doctor	0.2	0.4	2.8	-0.4	0.2	-1.5	0.1	-0.7	-0.1	0.2	-0.3	-0.3	-0.4	-1.7	0.0	-0.6	0.1	-0.8	-0.1	-0.7	0.2	0.3
Back pain experienced in last month	0.2	0.3	1.5	-0.8	-0.3	0.4	-0.3	-0.5	-0.5	-0.3	0.4	-0.5	0.0	0.2	-0.7	-0.2	-0.6	-1.2	-0.4	-0.4	-0.9	-0.4
Asthma (self-reported)	0.2	0.4	1.8	-0.8	0.7	-0.1	-0.8	-1.1	-0.2	0.2	-0.6	-0.8	-0.5	0.4	-0.4	-1.1	-0.2	-1.4	-0.8	-0.7	0.2	-0.2
Osteoarthritis (self-reported)	0.2	0.3	0.8	-0.9	-0.4	0.3	-0.4	0.1	-0.8	-0.1	0.4	-0.6	-0.6	0.4	-0.7	-0.5	-0.7	-0.1	-0.8	-0.5	-0.0	-0.7
Hearing aid user	0.2	0.2	1.3	0.1	-0.1	-0.3	-0.4	0.5	-0.1	-1.0	0.2	0.2	0.2	-0.2	0.2	0.0	-0.9	0.8	-0.1	0.2	-0.2	-1.2
High cholesterol (Self-reported)	0.2	0.4	3.1	-0.5	-0.6	-0.1	-0.4	-0.6	-0.5	-0.3	0.3	-0.5	-0.1	-1.8	-0.3	-0.4	-1.0	-0.6	-0.2	-0.5	-0.6	-0.9
Medication: Bendroflumethiazide	0.2	0.3	1.4	0.3	-1.2	-1.1	0.4	0.2	-0.1	-1.0	0.6	0.3	0.8	-0.5	0.0	0.8	-0.7	0.3	0.6	0.4	-0.1	0.3
Ever smoked	0.2	0.4	2.2	-0.0	0.1	-1.1	-0.1	-0.6	-0.2	-0.4	0.2	-0.0	-0.2	-0.2	-0.1	-0.1	-1.5	-0.1	-1.0	-0.8	1.4	0.0
Average weekly beer plus cider intake	0.2	0.3	1.2	-0.5	-0.7	-1.0	0.0	-0.5	-0.6	-0.5	0.7	-0.4	0.4	0.7	-0.6	-0.1	-1.1	-0.8	0.1	-0.4	-0.5	-0.3
Ever depressed for a whole week	0.2	0.2	1.4	-0.0	-0.1	-0.1	0.4	0.9	0.0	-0.0	0.3	0.2	0.6	0.1	0.1	0.3	0.9	-0.0	0.2	1.2	-0.8	0.6
Basal cell carcinoma (self-reported)	0.2	0.3	0.9	0.6	0.3	0.8	0.5	0.4	0.5	0.6	-0.2	0.6	0.4	0.2	0.4	0.3	0.5	0.7	0.0	0.5	0.7	1.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.8	0.1	0.0	-0.4	0.7	0.3	0.1	0.1	0.1	0.3	0.3	-1.3	0.1	0.5	0.6	0.4	-0.6	0.7	0.6	0.5
Pack years of smoking	0.2	0.4	1.7	-0.8	-0.7	-0.2	0.6	-0.6	-0.7	-0.6	0.8	-0.4	0.5	-1.3	-0.4	0.1	-0.3	-0.9	-0.1	-0.1	-0.8	0.2
Reaction Time	0.1	0.2	0.9	0.3	0.4	0.0	0.4	0.1	0.4	1.0	-0.3	0.2	0.2	0.9	0.0	-0.1	0.1	0.7	0.2	0.1	0.8	0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.7	-0.4	0.4	-0.7	-0.3	-0.1	-0.2	-0.0	-0.1	-0.3	-0.5	0.8	-0.2	-0.5	-0.1	-0.2	-0.4	-0.3	-0.4	-0.4
Crohns Disease (2012)	0.1	0.1	0.6	0.5	0.0	0.1	0.8	-0.2	0.3	0.0	-0.1	0.5	0.2	0.5	0.4	0.3	-0.0	0.7	0.6	-0.1	-0.3	0.2
Cardiovascular Disease	0.1	0.3	1.8	0.4	-0.3	0.2	0.5	0.6	0.1	-0.4	0.2	0.3	0.2	-1.4	0.1	0.6	-0.5	0.1	-0.2	0.5	1.2	0.5
Respiratory disease	0.1	0.3	1.3	0.4	0.5	0.5	0.4	0.5	0.7	0.7	-0.4	0.6	0.5	0.1	0.6	0.1	0.3	-0.2	0.1	1.0	1.1	1.0
Lung FEV1/FVC ratio	0.1	0.6	2.5	-0.4	0.7	0.1	-0.7	-0.4	0.2	0.6	-1.0	-0.6	-0.8	1.6	-0.2	-1.5	0.9	-1.1	0.8	-0.1	-0.3	0.3
Chronotype (morning person)	0.1	0.2	0.8	0.3	-0.2	0.6	0.5	0.4	0.2	0.9	0.1	0.5	0.3	0.6	0.5	0.3	0.5	0.6	0.9	0.2	-0.2	-0.1
Hearing difficulty/problems: Yes	0.1	0.2	1.7	0.1	-0.2	0.0	-0.1	-0.2	0.1	-0.4	-0.1	0.1	0.2	0.6	0.1	-0.0	-0.2	-0.1	0.5	-0.3	-1.3	-0.5
Relative age of first facial hair	0.1	0.3	2.1	0.3	0.5	0.2	0.1	0.9	0.2	0.5	-0.2	0.2	-0.2	1.5	0.2	-0.1	-0.4	-0.0	-0.4	0.3	1.0	0.3
Age when periods started (menarche)	0.1	0.2	1.3	0.4	-0.2	0.4	0.6	0.2	0.1	-0.1	0.2	0.3	0.1	-1.0	0.1	0.4	0.6	0.5	0.6	0.5	-0.3	1.1
High blood pressure	0.1	0.4	2.6	0.5	0.5	0.1	0.4	0.6	0.7	0.6	-0.5	0.5	-0.1	-0.9	0.8	0.4	0.2	0.4	0.4	0.3	1.6	1.0
Multivitamins +/- minerals	0.1	0.1	0.5	-0.0	-0.0	0.7	-0.2	-0.1	-0.2	0.0	0.1	-0.1	-0.4	0.3	-0.1	0.1	-0.6	0.5	-0.7	-0.2	-0.1	-0.2
Medication: Levothyroxine sodium	0.1	0.2	1.1	-0.2	0.3	0.6	0.2	-0.7	0.4	1.0	-0.6	0.1	-0.5	0.0	0.0	-0.7	0.7	0.4	0.4	-0.8	-0.0	-0.1
Pulse rate	0.1	0.2	0.5	0.4	-0.2	-0.4	0.5	0.1	0.0	-0.4	0.5	0.5	0.7	-0.4	0.0	0.6	0.1	-0.0	0.4	0.4	-0.7	0.2
Exposure to tobacco smoke at home	0.1	0.1	0.5	0.2	0.2	-0.3	0.4	0.1	0.2	-0.0	0.0	0.4	0.3	-0.1	0.0	0.3	-0.3	-0.4	-0.1	0.4	0.7	0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	3.5	-0.0	-0.3	0.5	0.2	-0.3	-0.2	-0.5	0.4	-0.1	0.2	1.9	-0.3	0.3	0.1	-0.2	-0.2	0.1	0.2	0.2
Exposure to tobacco smoke outside home	0.1	0.2	1.1	-0.3	0.3	-1.0	0.2	-1.0	-0.1	-0.4	0.2	-0.1	0.5	0.1	-0.1	0.2	-0.4	-0.7	-0.3	-0.3	0.3	-0.4
Medication for pain relief, constipation, heartburn	0.1	0.1	0.6	0.6	-0.1	-0.3	0.3	-0.0	0.2	-0.4	0.3	0.4	0.7	0.4	0.4	0.7	-0.5	0.5	0.1	-0.1	-0.2	-0.1
Medication: Blood pressure	0.1	0.1	0.7	0.0	0.2	-0.5	-0.0	0.3	0.0	0.2	-0.0	0.2	0.1	-0.3	0.4	0.1	-0.8	0.3	-0.3	0.1	0.7	-0.3
Family relationship satisfaction	0.1	0.2	0.9	0.3	0.3	0.1	0.1	0.5	0.2	0.2	-0.1	0.3	0.4	-0.9	-0.1	0.4	0.8	-0.4	-0.2	0.6	-0.4	0.5
Hypertension (Self-reported)	0.1	0.2	1.9	0.3	0.4	0.0	0.3	0.5	0.4	0.4	-0.3	0.4	-0.1	-0.8	0.6	0.3	-0.1	0.1	0.3	0.2	1.4	0.6
Illnesses of father: Heart disease	0.1	0.1	0.5	0.0	-0.7	-0.0	0.1	0.4	-0.2	0.0	0.4	0.0	0.5	0.2	0.2	0.1	-0.3	0.7	-0.2	0.5	0.5	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	0.5	-0.4	-0.2	-0.4	-0.0	-0.6	-0.5	-0.7	0.4	-0.4	-0.2	0.0	-0.5	-0.2	0.3	-0.3	-0.3	-0.7	-0.6	0.2
Miserableness	0.1	0.2	0.8	0.1	-0.0	-0.9	0.5	0.6	0.2	0.1	0.0	0.1	0.6	0.5	-0.2	-0.2	-0.2	-0.7	0.7	0.9	0.2	0.9
Myopia	0.1	0.2	0.8	0.2	0.4	0.4	0.3	-0.3	0.5	-0.0	-0.6	0.2	-0.1	-0.9	0.0	-0.3	0.4	0.3	0.7	0.0	0.3	0.6
Vascular/heart problems diagnosed by doctor	0.1	0.3	2.6	-0.1	-0.4	-0.0	-0.2	-0.2	-0.4	-0.5	0.4	-0.1	0.3	1.2	-0.5	-0.1	-0.0	-0.2	0.1	0.0	-1.6	-0.8
Tanning	0.0	0.5	1.3	-0.9	0.4	-0.2	-1.1	-0.5	-0.5	0.4	-0.3	-1.0	-0.8	-0.6	-1.1	-1.2	0.2	-1.0	-0.9	-0.2	0.1	-0.5
Medication: Blood pressure	0.0	0.1	0.4	-0.2	-0.3	0.7	0.4	-0.1	-0.2	-0.2	0.2	0.1	-0.1	-0.2	-0.2	0.2	-0.5	-0.4	0.3	-0.2	0.6	0.1

Hub : Genes

CCDC15

Models

Trait associations