Hub : Genes

CCDC176

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1230	0.0590	2.7e-03	0.052	NA	0.026	NA	0.035	7.4e-04	NA	1.4e-02	NA	5.1e-03
2	GTEx	Artery Tibial	0.0939	0.0349	1.7e-04	0.052	NA	0.020	NA	0.029	6.6e-05	NA	9.6e-03	NA	2.2e-03
3	GTEx	Brain Cortex	0.1920	0.0870	8.8e-03	-0.009	NA	0.016	NA	0.003	7.2e-01	NA	1.1e-01	NA	2.6e-01
4	GTEx	Brain Frontal Cortex BA9	0.2355	0.0821	1.2e-03	0.094	NA	0.135	NA	0.114	1.8e-03	NA	2.0e-04	NA	6.2e-04
5	GTEx	Esophagus Muscularis	0.0940	0.0430	5.6e-03	0.002	NA	0.017	NA	-0.005	2.5e-01	NA	3.0e-02	NA	9.3e-01
6	GTEx	Liver	0.3430	0.0920	3.4e-05	0.001	NA	0.039	NA	0.028	3.0e-01	NA	3.0e-02	NA	5.5e-02
7	GTEx	Testis	0.1490	0.0530	4.3e-04	0.068	NA	0.032	NA	0.055	6.0e-04	NA	1.4e-02	NA	1.9e-03
8	GTEx	Thyroid	0.1420	0.0450	1.1e-06	0.047	NA	0.094	NA	0.070	1.5e-04	NA	1.2e-07	NA	4.7e-06
9	GTEx	Whole Blood	0.0740	0.0320	1.6e-03	0.039	NA	0.005	NA	0.017	1.6e-04	NA	1.1e-01	NA	8.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.7	1.0	3.2	-0.3	-0.7	-0.7	-1.1	-1.8	-1.6	-0.6	-0.4	0.8
Bipolar Disorder or Schizophrenia	0.6	1.5	3.2	-1.6	-1.7	-0.8	-1.3	-1.0	-1.0	-0.5	-0.4	1.8
Depressed Affect (Nagel 2018)	0.7	1.6	4.2	1.4	2.0	1.4	1.1	0.8	0.7	0.2	1.5	-1.2
Depression (Nagel 2018)	1.0	1.6	4.4	0.5	0.9	2.1	1.4	0.5	1.4	1.5	1.3	-0.9
Intelligence (Savage-Jansen 2018)	0.7	2.2	7.9	-0.8	-1.1	-0.1	-1.0	-2.8	-0.6	-1.2	-1.7	2.0
Neuroticism (Nagel 2018)	0.1	0.2	0.5	-0.4	0.1	0.6	-0.7	-0.3	-0.1	-0.5	0.2	-0.6
Schizophrenia (2018)	0.5	1.0	3.1	-1.8	-1.6	-0.5	-0.8	0.2	0.1	-0.1	-0.3	1.7
Schizophrenia vs Biploar Disorder	1.5	1.9	4.8	0.9	1.3	0.5	1.5	2.2	1.3	1.2	1.0	-1.8
Worry (Nagel 2018)	0.7	1.4	4.3	-1.2	-0.8	0.4	-2.1	-0.9	-1.2	-1.7	-0.8	-0.4
Alzheimer’s Disease (in mother)	0.4	0.4	1.4	1.0	0.5	-0.4	0.5	-0.7	-0.5	-0.2	-0.4	1.2
Alzheimer’s Disease (in father)	0.7	0.8	3.4	0.5	0.6	0.9	0.7	0.7	-1.8	-0.3	1.0	0.4
Alzheimer’s Disease (including proxy)	0.7	1.0	1.7	1.3	1.0	1.1	1.3	-0.0	-1.2	0.1	0.9	1.0
Crohns Disease (2017)	0.2	0.4	0.9	-0.2	0.1	-0.2	-0.5	0.2	-0.8	-1.0	-0.9	0.8
Irritable Bowel Disease (IBD)	0.2	0.4	2.1	-0.0	0.2	0.3	0.1	1.0	1.4	0.5	0.5	-0.2
Ulcerative Colitis (UC)	1.0	1.8	8.5	0.3	0.3	0.8	0.7	1.1	2.9	1.3	1.7	-0.8
Major Depression (MDD)	1.1	1.3	4.8	0.7	0.7	2.2	1.2	1.4	1.0	0.8	1.0	-0.4
Reaction Time	0.8	1.4	5.5	2.3	2.2	-0.1	0.0	-0.9	0.2	-1.3	0.0	-0.5
Verbal and Numeric Reasoning (VNR)	0.9	2.3	8.0	-1.3	-1.5	-0.6	-1.0	-2.8	-0.3	-1.0	-2.1	1.3
Breast Cancer	0.2	0.6	1.4	-0.9	-0.7	1.2	0.3	0.2	0.1	0.9	1.0	-0.4
Ovarian Cancer	1.5	1.9	6.7	2.6	2.5	0.8	1.1	-0.8	-0.5	-1.0	-0.4	-0.7
Prostate Cancer	0.7	0.9	3.4	-0.0	0.1	-1.9	-0.8	-0.9	-0.8	-1.6	-0.7	-0.0
Age at First Birth	1.1	1.5	4.1	-1.7	-1.8	-0.8	-2.0	-0.6	-0.2	-0.7	-1.3	0.5
Bipolar Disorder (2011)	2.5	2.5	5.1	-1.2	-1.4	-1.4	-1.6	-1.1	-1.9	-1.8	-0.9	2.3
Body Mass Index (BMI) (2010)	1.1	1.5	5.0	2.2	2.0	0.7	1.3	0.6	0.9	-0.5	0.9	-0.0
Coronary Artery Disease (CAD)	0.3	0.3	1.9	-0.3	-0.3	-0.4	-0.3	1.4	-0.2	-0.0	-0.0	0.5
Crohns Disease (2012)	1.2	1.9	5.4	0.2	0.3	-1.1	-1.0	-0.3	-1.7	-2.3	-1.4	2.1
Mean Putamen Volume	1.0	1.1	5.5	-0.8	-0.5	-0.2	-0.2	0.0	1.6	0.9	-0.1	-2.3
Fasting Glucose	0.5	0.6	1.5	-0.2	-0.4	1.2	0.4	-0.4	0.9	1.2	1.1	-0.2
HbA1C	0.2	0.3	0.6	-0.7	-0.7	-0.2	-0.4	-0.3	0.6	-0.5	-0.8	-0.1
HDL Cholesterol	0.3	0.5	2.4	0.5	0.3	-0.2	1.6	-0.6	0.4	1.0	0.7	0.0
LDL Cholesterol	0.8	1.2	3.3	-1.2	-1.4	0.7	-0.3	-1.2	0.2	1.4	0.2	-1.8
Lupus	0.4	0.6	2.6	0.2	0.5	0.2	0.2	0.7	0.4	1.0	1.0	-1.6
Neuroticism (2016)	0.6	0.8	2.5	0.2	0.4	1.6	0.5	0.6	1.2	0.5	1.0	-1.1
Primary Biliary Cirrhosis	0.6	0.8	2.4	-0.7	-0.6	-1.6	-0.0	-0.7	0.7	-0.2	-1.1	-1.3
Rheumatoid Arthritis	1.2	1.7	7.2	1.4	1.5	-0.0	-1.0	0.1	-0.4	-2.7	-1.2	1.2
Schizophrenia (2014)	0.3	0.6	1.1	-0.9	-0.9	-1.1	-0.9	0.5	-0.6	-0.0	-0.4	1.0
Triglycerides	0.4	0.7	2.1	0.2	0.5	-1.2	-0.4	-0.6	0.7	-1.0	-1.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.6	-0.3	-0.4	1.4	1.2	0.1	0.9	1.1	0.1	-1.6
Ulcerative Colitis	0.9	1.3	9.2	-0.0	-0.1	0.0	-0.2	1.0	3.0	0.5	0.9	-0.3
Blood Eosinophil Count	0.1	0.8	3.1	1.8	1.8	0.2	-0.1	0.5	-0.1	-0.0	0.8	-0.6
Blood Platelet Count	0.4	5.1	12.2	1.2	1.2	3.5	2.4	3.4	1.1	2.1	2.8	-0.4
Blood Red Count	1.9	18.3	43.1	-1.4	-1.2	-6.5	-4.7	-3.9	-1.3	-6.6	-6.1	-0.1
Blood White Count	0.4	2.8	8.2	2.8	2.9	0.4	1.5	0.5	1.0	1.0	2.0	-1.0
Heel T-Score	0.2	1.5	2.9	-1.0	-0.5	1.3	-1.2	1.0	-1.7	-1.6	-1.5	0.5
BMI	1.0	6.0	14.8	3.2	3.7	1.6	3.8	0.4	0.7	0.9	3.2	-1.4
Height	0.5	9.1	20.4	-1.6	-1.8	3.2	2.2	2.6	3.3	4.5	3.2	-3.5
Waist Hip Ratio (WHR)	0.2	0.9	5.6	-0.6	-0.5	0.1	-0.2	2.4	-1.1	0.1	0.3	0.6
Systolic Blood Pressure	0.3	1.3	3.4	-0.5	-0.1	-1.8	-1.4	-0.4	-1.9	-1.4	-0.8	-0.4
Smoking Status	0.3	0.6	2.7	-0.1	-0.1	1.6	0.9	-0.4	0.5	1.1	0.2	-0.9
Allergy or Eczema	0.3	0.7	2.1	1.1	1.0	-0.0	0.1	-0.3	-0.2	-1.4	-0.6	1.3
Cardiovascular Disease	0.2	0.6	1.7	0.9	1.1	0.5	0.2	-0.7	-0.8	0.1	0.6	-1.3
Hypothyroidism (self reported)	0.2	0.5	1.7	-0.5	-0.5	1.3	-0.6	0.8	0.8	0.2	0.5	0.6
Respiratory disease	0.3	0.6	1.2	1.1	1.1	0.8	1.0	0.1	-0.8	-0.2	0.9	0.2
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.6	0.4	0.6	0.5	1.9	0.4	0.2	1.7	1.4	-1.6
Lung FEV1/FVC ratio	1.0	5.2	21.9	-0.5	-0.5	-4.7	-1.8	-2.0	0.4	-1.7	-3.7	0.3
Lung FVC	1.2	5.9	12.3	-0.2	-0.9	-3.2	-3.5	-1.5	-1.1	-3.2	-3.3	2.3
Neuroticism	0.2	0.4	1.6	0.7	1.2	0.4	0.4	0.1	0.2	-0.0	0.6	-1.0
Chronotype (morning person)	3.1	7.3	20.2	-0.3	-0.4	4.5	3.1	1.3	2.7	3.7	3.1	-1.8
Hair Pigment	0.0	0.9	4.0	-2.0	-1.8	-0.5	0.1	0.2	-0.1	0.3	0.1	0.7
Tanning	0.1	0.8	2.7	1.6	1.4	0.5	0.7	0.8	0.2	0.3	0.9	-0.4
Hand grip strength (left)	0.5	1.4	3.3	1.4	1.7	0.1	0.0	1.8	-1.0	-0.7	0.3	1.7
Number of treatments/medications taken	1.4	2.5	8.6	1.4	1.6	2.9	1.5	1.1	0.5	0.8	2.0	-1.0
Average weekly spirits intake	0.7	0.9	2.8	-0.1	0.0	1.1	0.8	1.7	0.3	1.5	0.9	-0.5
Sensitivity / hurt feelings	0.3	0.6	1.7	-0.5	-0.5	0.1	0.4	0.5	1.3	1.2	0.2	-0.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.9	0.5	0.9	0.7	0.6	0.3	-0.3	0.4	0.4	-0.7
Hearing difficulty/problems: Yes	0.7	1.0	2.3	0.2	0.1	-1.1	-1.2	-1.0	-1.1	-1.3	-1.5	-0.2
Relative age of first facial hair	0.2	0.3	1.8	-0.4	-0.5	-1.3	-0.1	0.1	-0.3	-0.2	-0.6	-0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	-0.8	-0.8	0.4	-0.9	-0.4	-0.6	-0.2	-0.9	-0.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.1	0.1	0.3	0.1	0.0	-0.0	-1.2	-0.1	-0.1	-1.4
Ever had hysterectomy (womb removed)	1.5	1.6	4.8	-1.2	-1.1	-2.2	-1.4	-0.9	-0.5	-0.7	-1.9	0.7
Systolic blood pressure, automated reading	0.6	1.7	7.2	-0.4	-0.1	-2.7	-1.0	0.2	-2.1	-1.2	-0.9	0.2
Eye problems/disorders: Diabetes related eye disease	3.9	4.3	11.4	-0.2	-0.3	-2.3	-2.0	-3.4	-1.4	-2.8	-2.5	1.2
Angina	0.4	0.5	1.9	0.9	1.1	0.5	-0.1	1.4	-0.2	-0.0	0.1	-0.5
Medication for hormone replacement therapy	0.7	0.8	3.0	-0.3	-0.2	-0.7	0.1	-1.2	0.8	1.3	-0.0	-1.7
Vitamin and mineral supplements	3.6	4.8	13.3	0.4	0.3	1.8	1.7	1.3	3.2	3.6	2.0	-2.8
Supplements: Zinc	1.5	1.6	3.7	1.3	1.3	0.8	1.7	1.4	0.8	1.2	1.9	-0.3
Medication: Co-codamol	0.2	0.2	0.6	0.2	0.4	0.3	0.8	-0.5	-0.3	0.2	0.7	0.1
Medication: Metformin	0.8	1.1	3.9	0.5	0.5	0.2	1.4	-0.3	1.6	0.8	0.8	-2.0
Diabetes (father)	0.3	0.3	0.9	0.1	0.1	-0.6	-0.4	1.0	0.3	-0.6	-0.1	1.0
Diabetes (mother)	0.3	0.4	1.1	-0.0	-0.0	-0.1	0.9	-0.7	-0.2	0.8	0.9	-1.0
Severe depression (siblings)	0.3	0.4	1.3	-0.4	-0.3	0.3	-0.5	-1.0	0.4	-0.1	-0.5	-1.1
Pack years adult smoking proportion	1.8	2.8	5.4	1.3	1.6	1.6	2.3	1.7	0.6	1.8	2.1	-1.5
Impedance of leg (right)	0.9	4.4	15.0	-3.9	-3.8	1.9	-2.4	0.8	0.1	0.8	-0.4	0.1
Leg fat-free mass (left)	0.7	3.5	9.9	2.2	2.3	0.5	3.1	0.3	1.3	1.4	2.4	-1.5
Trunk fat percentage	0.9	3.7	6.2	0.3	0.8	2.3	2.5	1.2	2.4	1.8	2.3	-2.4
Hand grip strength (right)	0.4	1.1	3.9	1.1	1.3	-0.0	0.5	2.0	-0.2	0.2	0.9	1.3
Townsend deprivation index at recruitment	1.1	1.5	2.9	1.4	1.3	-0.2	1.6	0.3	-1.1	1.3	1.7	-1.2
Current tobacco smoking	0.3	0.4	2.4	0.7	0.4	-0.4	0.6	-0.0	-1.5	0.6	0.3	-0.3
Average weekly fortified wine intake	0.7	0.8	2.8	-0.6	-0.4	0.7	-1.0	0.7	-0.7	-1.0	0.7	1.7
Maternal smoking around birth	0.1	0.2	1.1	-0.3	-0.2	-0.2	-0.4	0.4	0.3	0.2	0.0	-1.1
Fed-up feelings	0.9	1.6	5.9	1.9	2.4	0.5	1.2	1.4	-0.2	-0.2	1.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.0	0.7	0.9	1.1	0.7	0.5	1.7	1.1	1.2	-1.4
Relative age voice broke	0.1	0.2	0.5	0.6	0.3	-0.1	0.7	0.3	0.4	0.5	0.7	-0.1
Taking other prescription medications	0.3	0.5	2.5	-0.3	0.0	1.6	0.1	-0.6	0.4	-0.3	0.7	-0.8
Age when periods started (menarche)	0.3	0.7	3.1	-0.6	-0.5	-0.0	-1.0	-0.1	-1.8	-0.8	-1.1	0.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.9	0.9	1.0	-0.1	1.1	-0.6	0.0	0.2	0.4	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	5.6	-1.5	-1.2	-1.0	-1.8	-1.1	-2.4	-2.2	-2.0	1.5
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.6	0.5	0.5	1.3	1.1	0.8	1.6	1.5	1.9	-1.2
Qualifications: CSEs or equivalent	0.4	0.5	1.5	-0.8	-0.7	-0.2	-0.9	0.4	-0.1	-0.8	-1.2	0.3
Serious illness, injury or assault to yourself	0.4	0.5	1.7	1.2	1.3	0.2	1.1	-0.1	-0.2	0.1	0.2	-0.4
High blood pressure	0.3	0.7	2.5	1.2	1.3	-0.0	0.3	-0.0	-1.6	-0.3	0.8	0.2
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.5	1.3	1.2	-0.4	-0.0	0.0	0.2	-1.6	-0.6	0.5
Multivitamins +/- minerals	2.6	3.4	9.3	0.1	0.4	-1.2	-1.2	-0.7	-3.0	-3.0	-1.4	2.5
Stomach or abdominal pain in last month	0.2	0.3	1.0	0.1	0.6	-1.0	-0.3	-0.3	-0.2	-0.8	-0.0	0.5
Supplements: Glucosamine	0.4	0.5	2.4	0.4	0.3	-0.1	0.5	1.6	0.2	0.4	0.9	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.4	-0.1	0.1	-0.3	-0.4	-0.7	-1.6	-1.0	-0.7	0.4
Medication: Atenolol	1.4	1.7	3.8	1.2	1.5	1.9	1.0	1.1	1.3	0.8	1.6	-1.1
Medication: Levothyroxine sodium	0.4	0.6	2.2	-1.5	-1.3	0.9	-0.6	0.2	0.3	0.5	0.4	-0.1
Sitting height	0.3	1.8	5.0	-1.0	-1.2	0.9	0.4	-0.9	2.2	2.1	0.8	-1.3
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	-0.3	-0.0	-0.9	-1.0	-0.2	-1.5	-1.2	-0.3	0.9
High blood pressure (mother)	0.5	0.6	1.4	0.6	0.9	1.1	0.4	0.7	0.6	0.2	1.2	-1.0
Body mass index (BMI)	0.7	2.9	7.8	2.0	2.4	0.1	2.8	0.3	1.2	0.8	1.9	-1.8
Impedance of leg (left)	0.8	3.8	12.4	-3.5	-3.4	2.0	-2.1	0.9	0.4	0.9	-0.0	-0.0
Leg predicted mass (left)	0.7	3.8	10.6	2.2	2.3	0.5	3.3	0.4	1.4	1.5	2.5	-1.5
Trunk fat mass	1.1	4.8	8.8	0.7	1.1	2.0	3.0	1.2	2.6	2.3	2.7	-2.8
Waist circumference	0.8	3.1	8.8	1.1	1.3	0.8	3.0	1.0	1.6	1.8	2.1	-2.1
Number of incorrect matches in round	0.7	1.2	3.2	-1.2	-1.3	-0.7	-0.8	-1.8	0.8	-0.1	-1.4	-0.3
Past tobacco smoking	0.7	1.2	3.4	0.6	0.5	-1.7	-1.3	0.6	-1.8	-1.2	-0.2	0.8
Alcohol usually taken with meals	0.4	0.7	1.9	1.4	1.3	-0.4	0.6	-0.0	1.1	-0.5	0.3	1.0
Nervous feelings	0.7	1.3	3.2	-0.7	-0.5	-0.4	-1.4	-1.2	-1.8	-1.8	-0.5	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	2.7	1.2	1.7	0.8	0.6	0.3	0.4	-0.1	1.2	-1.5
Hearing difficulty/problems with background noise	2.6	4.2	8.6	0.2	0.2	-1.8	-1.9	-2.9	-2.6	-2.9	-2.3	1.2
Hair/balding pattern: Pattern 2	0.6	0.7	3.6	-0.2	-0.1	-0.3	-0.3	0.6	-1.9	-0.7	-0.3	1.2
Had menopause	0.9	1.1	3.5	-1.2	-1.4	0.5	-0.8	1.9	-0.2	0.5	0.1	-1.5
Had other major operations	1.7	2.0	6.5	2.5	2.4	-1.5	1.4	1.0	-0.8	-0.3	0.3	0.3
Forced vital capacity (FVC)	0.2	0.6	2.2	-0.4	-1.0	-1.0	-1.5	-0.5	0.9	-0.2	-0.6	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.4	-0.6	-0.3	-0.0	-1.0	-0.3	-1.8	-1.4	-1.1	1.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.1	1.1	1.0	-0.9	0.2	-1.0	-0.5	-0.4	0.3	0.0
Qualifications: None of the above	3.2	6.9	14.0	0.6	0.7	2.6	3.3	2.6	0.4	3.7	3.3	-3.5
Financial difficulties in last 2 years	0.9	1.2	3.2	0.5	0.8	-1.6	-0.3	0.7	-1.8	-1.6	-1.0	-0.1
Mouth/teeth dental problems	0.4	0.6	1.3	-0.7	-0.8	-0.8	-1.0	-0.3	0.2	-0.6	-1.0	1.1
Heart attack	0.9	1.1	2.3	1.2	1.5	0.3	1.2	1.5	1.0	0.8	0.8	-0.3
Allergy	0.4	1.0	3.8	-1.2	-1.1	-0.1	-0.2	-0.1	1.1	1.9	0.5	-1.1
Pain all over the body in last month	0.4	0.4	1.7	-0.1	-0.1	0.4	1.2	-0.0	0.8	1.3	0.2	-0.3
Diabetes (self-reported)	1.3	2.0	5.2	1.0	1.1	-0.2	2.3	-0.1	0.8	1.7	2.0	-1.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.0	-0.2	-0.2	1.4	-0.3	0.3	0.1	-0.0	0.3	0.3
Medication: Ramipril	0.6	0.8	2.0	0.5	0.5	1.4	0.9	1.4	0.7	0.6	0.7	-0.6
Medication: Simvastatin	0.3	0.4	1.2	0.9	1.0	-1.1	0.4	-0.2	-0.4	-0.3	-0.5	-0.5
Fluid intelligence score	0.7	1.4	5.2	-0.5	-0.7	-0.8	-0.8	-2.3	-0.8	-0.8	-1.3	1.4
Illnesses of siblings	0.8	1.1	2.0	1.1	1.3	1.4	1.4	0.7	1.4	0.7	0.2	-0.8
Neuroticism score	0.1	0.2	0.6	0.0	0.5	-0.1	-0.7	-0.5	-0.5	-0.8	0.1	-0.3
Weight	1.0	4.9	11.6	1.7	1.9	1.2	3.4	1.1	2.0	2.2	2.9	-2.3
Impedance of arm (right)	0.7	3.4	8.6	-2.7	-2.8	2.9	-2.0	0.4	1.4	0.2	-0.6	0.6
Arm fat percentage (right)	0.7	2.9	5.7	0.9	1.3	1.7	2.3	0.8	2.4	1.5	1.9	-1.9
Trunk fat-free mass	0.6	3.2	7.8	1.6	1.6	0.0	2.8	1.0	1.2	2.0	2.4	-1.6
Hip circumference	1.0	4.4	11.5	1.2	1.4	1.4	3.4	0.4	2.3	2.4	2.9	-1.9
Time employed in main current job	0.6	0.7	1.7	-0.9	-0.9	-0.6	-1.1	-1.3	-0.6	-0.5	-0.5	-0.6
Alcohol intake versus 10 years previously	0.5	0.7	2.0	0.7	0.6	1.0	1.4	-0.1	0.1	1.0	1.0	-0.7
Father’s age at death	0.2	0.3	1.7	0.2	0.0	-0.3	0.3	1.3	0.2	0.5	-0.2	0.7
Worrier / anxious feelings	0.5	1.0	3.9	-0.2	0.3	0.0	-1.3	-0.6	-1.3	-2.0	-1.1	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	5.9	1.9	2.1	1.6	2.4	0.3	-0.3	1.4	2.4	-0.8
Falls in the last year	0.9	1.2	3.8	0.6	0.9	1.9	1.6	0.6	-0.1	0.3	1.6	0.5
Hair/balding pattern: Pattern 3	0.5	0.7	2.1	0.8	0.6	0.8	0.9	0.7	0.7	1.4	0.8	-0.7
Number of live births	1.6	2.2	5.6	2.4	2.3	-0.9	1.6	1.1	-1.2	0.2	1.3	-1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	6.2	-1.0	-1.5	-2.5	-2.4	-1.2	0.9	-1.2	-2.0	0.7
Pulse rate	0.2	0.4	1.5	0.3	0.2	-0.6	-0.0	-1.2	-0.7	-0.9	0.0	0.1
Happiness	2.1	2.6	6.0	-0.7	-0.5	-1.8	-0.8	-2.4	-2.3	-1.7	-1.5	1.4
Noisy workplace	0.2	0.2	0.6	0.4	0.1	-0.8	-0.6	0.5	0.5	0.2	-0.3	-0.4
Qualifications: A levels/AS levels or equivalent	0.5	1.1	6.1	0.9	0.9	-0.3	0.4	-0.1	0.2	-1.2	-0.2	2.5
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.9	1.6	1.7	-2.0	1.2	-0.0	-1.2	-0.9	-0.1	0.5
Mouth/teeth dental problems: Dentures	0.7	1.2	4.0	0.1	-0.1	0.8	1.3	-0.4	0.6	2.0	-0.2	-1.9
Asthma	0.6	1.1	3.2	0.8	0.8	0.5	0.4	0.8	-1.8	-1.2	0.7	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	2.5	1.6	1.2	0.8	1.6	0.5	-0.4	1.0	1.5	-0.3
Medication: Cholesterol lowering	0.2	0.3	2.1	0.2	0.3	0.0	0.2	-0.6	0.5	0.1	0.1	-1.4
Depression (self-reported)	0.5	0.6	3.1	-0.8	-0.5	1.8	-0.3	-1.0	0.7	0.1	-0.2	-0.6
Medication: Lansoprazole	0.3	0.4	1.3	-0.1	0.4	1.1	-0.2	-0.3	1.1	-0.3	0.7	-0.5
Prospective memory result	0.4	0.5	1.9	0.3	0.5	-0.1	1.4	-0.0	1.0	0.4	-0.0	-1.0
Lung cancer (father)	1.3	1.5	3.0	-1.7	-1.6	-1.4	-1.1	-1.2	0.2	-0.7	-1.6	-0.6
Illnesses of mother	0.2	0.3	0.5	-0.6	-0.7	-0.4	0.4	-0.7	0.5	0.7	0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	7.4	-0.6	-1.1	-2.7	-2.6	-1.9	0.5	-1.7	-2.2	0.8
Pulse wave Arterial Stiffness index	0.1	0.2	0.5	-0.2	-0.2	0.7	0.3	0.6	-0.5	-0.1	0.2	-0.4
Impedance of arm (left)	0.6	2.8	9.0	-2.4	-2.5	3.0	-1.4	0.5	1.5	0.5	-0.3	0.2
Arm fat mass (right)	1.0	4.0	9.0	1.3	1.6	1.5	3.0	0.7	2.2	1.9	2.5	-2.3
Trunk predicted mass	0.6	3.2	8.2	1.6	1.6	0.0	2.9	0.9	1.2	2.1	2.4	-1.6
Standing height	0.3	3.5	9.2	-0.9	-1.2	1.9	1.2	1.6	2.0	3.0	2.2	-1.7
Length of working week for main job	0.1	0.1	0.3	0.4	0.3	0.2	-0.5	-0.3	0.1	-0.5	0.0	-0.1
Exposure to tobacco smoke at home	0.7	0.8	1.7	1.3	1.0	-0.5	1.2	-1.1	-0.6	-0.4	0.8	-0.6
Breastfed as a baby	0.1	0.1	0.8	0.0	0.1	0.9	-0.3	0.0	-0.6	-0.1	-0.1	-0.1
Tense / ‘highly strung’	0.9	1.5	6.2	-0.2	-0.1	1.8	0.5	0.9	0.3	1.5	2.5	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	4.2	-0.8	-0.7	1.8	-0.1	-0.5	1.7	1.3	1.1	-2.0
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	1.2	1.2	-1.0	0.8	0.5	1.7	0.1	-0.6	-0.7
Birth weight of first child	0.2	0.4	1.5	-0.8	-0.9	-0.5	-1.2	-0.5	0.0	-0.2	0.0	-0.1
Peak expiratory flow (PEF)	1.7	3.9	9.4	-1.4	-1.6	-3.1	-2.9	-1.8	1.4	-1.5	-2.3	-0.9
Pulse wave reflection index	0.5	0.6	1.5	-1.1	-1.0	1.2	-0.4	0.5	-0.3	-0.4	-0.3	1.0
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.3	0.1	0.2	0.3	-0.6	-1.1	-0.7	-0.8	-0.3	0.2
Loud music exposure frequency	0.3	0.4	1.0	0.1	-0.0	0.3	-0.1	-0.8	0.4	0.8	0.9	-1.0
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	5.3	-0.9	-0.8	-1.1	-1.3	-0.9	-0.6	-1.9	-1.3	2.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.7	1.0	-0.7	0.1	1.2	-0.6	-0.9	0.4	0.2
Blood clot in the leg (DVT)	0.9	1.2	3.7	-0.0	0.1	-0.5	-0.3	-1.1	-1.5	-1.9	-1.6	0.8
Medication: Paracetamol	0.4	0.6	1.9	0.7	0.7	-1.2	0.2	-0.2	-1.4	-0.8	-0.5	0.6
Headache pain in last month	0.7	1.1	2.9	1.6	1.7	0.2	0.8	-0.1	-0.9	-0.9	1.3	1.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.5	-0.1	-0.2	-0.8	-0.2	-0.1	-0.8	-0.8	-0.8	1.9
Glaucoma (self-reported)	1.2	1.4	5.5	0.2	0.3	-0.1	-1.3	-2.3	-0.6	-1.9	-0.4	1.0
Gout (self-reported)	0.9	1.3	4.9	-0.9	-0.8	-1.6	-0.7	-2.2	-0.4	-0.5	-1.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.7	-1.1	-1.0	1.3	-0.5	0.6	1.2	0.5	0.8	0.3
Medication: Amlodipine	0.3	0.5	0.8	0.6	0.9	-0.6	0.3	-0.8	0.8	0.2	0.5	-0.9
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.1	-0.4	-0.3	0.5	-0.5	0.0	-1.1	-0.2	0.4	0.1
Birth weight	0.8	1.6	4.0	-0.2	-0.6	-2.0	-1.2	-1.9	1.0	-0.7	-1.5	-1.2
Chronic bronchitis/emphysema (mother)	1.1	1.2	6.2	0.8	0.9	0.8	1.2	2.5	0.5	0.8	0.4	-0.6
High blood pressure (siblings)	1.0	1.5	2.7	-1.3	-1.6	-1.5	-1.6	-1.1	-0.5	-0.8	-1.3	0.2
Forced vital capacity (FVC), Best measure	0.2	0.9	2.5	0.0	-0.6	-1.2	-1.6	-1.0	0.3	-0.9	-0.9	0.8
Body fat percentage	1.0	4.0	7.0	0.4	0.9	2.2	2.6	1.1	2.4	2.0	2.4	-2.6
Leg fat percentage (right)	1.0	3.8	9.2	0.1	0.7	1.7	2.3	0.8	2.4	2.2	2.2	-3.0
Arm fat-free mass (right)	0.5	2.7	7.6	1.7	1.8	-0.3	2.8	0.6	0.5	1.5	2.4	-1.4
Exposure to tobacco smoke outside home	0.8	1.1	2.7	1.7	1.6	0.1	0.1	0.8	-1.1	-1.5	-0.2	0.5
Comparative body size at age 10	0.3	1.0	3.1	0.4	0.5	-0.9	-0.2	-1.8	0.3	-1.0	-1.7	-0.3
Number of full brothers	0.7	0.8	2.0	-0.6	-0.5	-1.2	-0.7	-1.4	-1.4	-0.5	-0.2	0.8
Worry too long after embarrassment	1.2	2.0	5.5	-1.2	-1.3	-2.3	-1.7	-1.3	-0.8	-1.2	-1.6	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.7	-0.8	-0.7	1.5	-0.1	-1.6	0.5	0.4	0.7	-0.3
Wheeze or whistling in the chest in last year	0.9	1.6	4.4	1.2	1.5	1.8	1.3	1.1	-0.3	0.1	2.1	-0.0
Number of children fathered	0.8	1.0	3.0	1.1	1.2	-1.7	-0.0	0.5	0.7	0.4	-0.8	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.1	-0.3	-0.1	0.8	1.2	1.3	0.8	1.4	0.8	-0.5
Age at first live birth	0.1	0.1	0.3	-0.6	-0.3	-0.3	-0.4	-0.3	0.3	0.0	-0.5	0.4
Pulse wave peak to peak time	0.1	0.2	0.5	0.2	0.1	-0.3	0.0	-0.3	0.7	0.7	0.3	0.0
Health satisfaction	2.6	3.4	9.9	3.1	3.1	-1.0	2.9	-0.5	-1.0	-0.6	0.7	0.4
Shortness of breath walking on level ground	0.6	0.7	1.6	0.8	1.2	0.9	1.3	-0.9	-0.6	0.3	0.9	0.2
Qualifications: College or University degree	1.5	4.9	13.6	-0.6	-0.8	-2.3	-2.0	-3.7	-0.5	-2.5	-2.7	2.6
Eye problems/disorders: None of the above	0.3	0.3	1.0	0.5	0.6	0.5	-0.2	1.0	-0.5	-0.7	-0.0	0.5
Mouth/teeth dental problems: Loose teeth	1.0	1.2	5.6	-0.1	-0.1	1.2	-0.1	2.4	-1.3	0.4	1.1	-0.4
Emphysema/chronic bronchitis	0.3	0.3	1.4	0.2	0.1	-0.0	1.1	-0.3	-0.5	1.2	0.3	0.1
Medication for pain relief, constipation, heartburn	0.5	0.9	2.3	-1.4	-1.5	-0.1	-1.2	-0.1	0.6	-0.2	-1.3	0.6
Neck or shoulder pain in last month	0.8	1.1	3.6	0.9	1.0	0.7	1.1	0.3	0.4	0.8	1.9	-1.3
Medication: Blood pressure	0.3	0.5	0.9	0.5	0.7	0.7	0.7	0.9	0.3	0.7	0.7	-0.8
Angina (self-reported)	0.3	0.4	1.3	0.7	0.9	0.6	-0.1	1.2	0.1	0.1	-0.0	-0.8
Migraine (self-reported)	1.1	1.4	4.2	1.4	1.2	-0.6	-0.1	-0.9	-1.1	-1.6	-0.2	2.1
Medication: Ibuprofen	1.3	1.5	3.5	1.7	1.3	0.5	1.5	1.2	-0.1	1.1	1.9	-0.3
Medication: Allopurinol	0.5	0.6	2.1	0.2	0.4	-1.2	0.3	-1.2	0.4	0.1	-0.5	-1.4
Medication: Omeprazole	0.5	0.6	1.8	1.2	1.3	-0.2	0.5	-1.3	-0.0	-0.5	0.3	-0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.2	0.2	0.1	0.3	0.3	-0.3	0.0	0.1	-0.3	-0.5
Mean time to correctly identify matches	0.6	1.1	4.0	2.0	1.9	-0.3	0.2	-0.2	-0.3	-0.9	-0.3	-0.8
Heart disease (mother)	0.9	1.1	2.9	0.6	0.7	-0.3	-0.4	-0.3	-1.7	-1.3	-1.5	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.7	-0.4	-0.3	-0.3	-0.7	-0.5	-1.3	-1.0	-0.3	-0.3
Whole body fat mass	1.1	4.8	9.2	0.7	1.2	1.9	3.0	1.0	2.5	2.3	2.7	-2.9
Leg fat mass (right)	0.9	3.5	7.1	0.5	0.9	1.5	2.5	0.6	2.1	2.0	2.4	-2.7
Arm predicted mass (right)	0.5	2.4	7.5	1.6	1.6	-0.5	2.7	0.4	0.5	1.4	2.2	-1.3
Pulse rate, automated reading	0.5	1.5	4.4	1.6	1.4	-2.1	0.8	-1.8	0.2	-0.7	-0.2	-0.3
Alcohol intake frequency.	0.3	0.8	2.7	1.1	1.1	0.3	1.2	0.1	-0.6	0.2	0.2	-1.7
Comparative height size at age 10	0.2	1.3	2.8	-1.1	-1.0	1.7	0.2	1.4	-0.6	1.5	1.4	-0.1
Number of full sisters	1.2	1.5	4.5	1.2	1.3	0.4	1.2	0.5	1.1	1.5	0.4	-2.1
Suffer from ‘nerves’	1.3	2.0	4.8	-0.5	-0.2	-0.7	-2.2	-1.2	-2.1	-2.2	-0.6	1.2
Overall health rating	1.3	2.9	6.8	2.5	2.6	0.1	2.4	0.4	0.2	1.2	1.7	-1.5
Chest pain or discomfort	0.2	0.3	0.8	0.9	0.8	-0.1	0.3	-0.1	-0.6	-0.6	0.2	-0.0
Had major operations	0.3	0.3	1.0	0.4	0.5	-0.7	0.3	0.3	0.5	0.7	-0.0	-1.0
Age at last live birth	0.1	0.2	0.5	0.5	0.6	-0.4	-0.1	0.2	0.0	0.2	-0.7	-0.5
Family relationship satisfaction	1.3	1.5	3.7	1.0	0.8	-1.5	-0.8	-1.1	-1.1	-1.8	-1.9	-0.0
Leg pain on walking	0.6	0.8	2.7	0.8	1.0	0.3	1.7	-0.3	-1.4	-0.2	0.4	0.8
Qualifications: NVQ or HND or HNC or equivalent	3.0	3.6	8.5	0.2	0.6	2.9	1.7	2.1	2.4	2.5	1.7	-1.0
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.2	1.4	1.5	0.2	0.4	1.1	1.0	0.0	0.5	0.6
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	4.0	-2.0	-1.9	1.2	-1.1	-0.7	1.2	0.6	-0.0	0.5
Medication: Aspirin	0.5	0.6	1.6	0.6	0.8	0.5	0.9	1.3	0.0	0.3	1.3	-0.5
Supplements: Vitamin C	0.6	0.7	3.8	-0.7	-1.0	0.2	-0.5	-1.9	-0.5	-0.6	0.3	0.5
Knee pain experienced in last month	0.9	1.4	3.5	-0.1	-0.0	1.6	1.9	0.6	-0.6	1.5	1.8	-0.5
Hypertension (Self-reported)	0.2	0.6	2.2	1.1	1.2	-0.2	0.3	-0.0	-1.5	-0.3	0.6	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.1	-1.2	-1.1	-1.8	-2.0	-1.6	-0.8	-1.8	-1.3	0.7
Illnesses of father: Heart disease	0.9	1.2	5.3	-0.2	-0.2	-0.4	-1.2	-0.4	-0.9	-1.7	-0.5	2.3
Illnesses of siblings: Diabetes	0.1	0.2	1.0	0.2	0.0	-1.0	0.0	0.1	-0.5	0.2	0.6	0.0
Smoking status: Previous	1.1	1.7	5.5	-1.6	-1.6	1.1	0.5	-1.0	2.4	1.0	-0.6	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.0	-1.1	-1.3	0.6	-0.1	0.1	0.6	1.4	1.4	0.3
Whole body fat-free mass	0.6	3.7	10.0	2.1	2.1	0.2	3.2	0.8	1.3	1.8	2.5	-1.6
Leg fat-free mass (right)	0.8	4.1	11.0	2.6	2.6	0.3	3.3	0.5	1.3	1.3	2.5	-1.3
Arm fat percentage (left)	0.9	3.4	6.8	1.2	1.6	1.7	2.6	0.6	2.4	1.5	2.1	-2.1
Average weekly red wine intake	0.6	0.9	1.5	-1.2	-1.2	0.0	-1.1	-1.0	-0.5	-0.9	-0.7	1.2
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.9	-1.2	-1.4	0.7	-0.9	-0.3	0.9	0.5	0.3	-0.6
Mood swings	0.7	1.3	3.5	1.2	1.6	0.8	0.4	-0.2	1.1	0.4	1.2	-1.9
Loneliness, isolation	0.2	0.2	1.4	-0.3	0.3	0.6	-0.2	-0.3	-0.0	-0.0	-0.4	-1.2
Long-standing illness, disability or infirmity	0.2	0.4	1.3	0.3	0.3	-0.2	0.3	-0.6	-1.0	0.0	0.6	-1.1
Ever had bowel cancer screening	0.3	0.3	1.1	0.2	0.5	-0.6	0.6	0.5	0.4	0.5	0.1	-1.0
Diabetes diagnosed by doctor	1.8	3.0	6.7	0.8	1.0	1.0	2.6	0.5	1.1	2.4	2.5	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.3	0.3	0.6	-0.4	0.2	0.9	-0.1	0.7	1.1	-0.3
Friendships satisfaction	0.9	1.1	2.8	0.6	0.6	-0.8	-0.4	-1.0	-1.7	-1.2	-1.2	1.4
Qualifications: nursing, teaching	2.8	4.3	7.6	-0.4	-0.6	-2.4	-1.9	-2.7	-0.3	-2.6	-2.5	2.8
Commuting to job workplace: Walk	0.5	0.6	1.9	-0.9	-1.4	0.6	-0.1	-0.8	-0.7	0.2	0.6	-0.7
Eye problems/disorders: Cataract	0.5	0.5	1.4	-0.7	-0.9	-1.2	-0.4	0.5	-0.3	0.2	-1.1	0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.3	-0.3	-0.3	-1.1	-0.8	-1.5	-1.2	-1.0	-0.8	0.2
Medication for cholesterol	0.3	0.5	2.5	-0.1	-0.2	0.4	-0.3	1.6	0.8	-0.5	-0.4	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.0	-0.2	-0.1	0.6	-0.4	0.8	-2.0	-0.4	0.4	1.6
Back pain experienced in last month	1.8	2.6	8.8	1.2	1.7	0.6	1.5	3.0	0.4	0.8	2.2	-1.3
Mineral and other dietary supplements	0.4	0.6	1.4	-0.5	-0.7	0.6	-0.4	-1.2	0.8	1.2	0.5	0.6
Breast cancer (self-reported)	2.5	3.0	8.9	-1.6	-1.6	-3.0	-1.6	-1.9	-0.5	-1.5	-2.1	0.1
Asthma (self-reported)	0.6	1.2	3.8	0.8	0.8	0.4	0.3	0.6	-2.0	-1.5	0.5	1.7
Osteoporosis (self-reported)	0.3	0.4	0.9	-0.8	-1.0	0.3	-0.7	0.8	0.1	-0.4	-0.1	0.5
Osteoarthritis (self-reported)	0.3	0.4	1.2	0.6	0.5	0.6	1.1	-0.4	-0.4	0.1	0.9	0.7
Medication: Aspirin	0.4	0.5	1.4	0.5	0.6	0.2	0.5	1.2	-0.2	0.2	1.1	-0.8
Medication: Gliclazide	0.9	1.1	3.2	1.0	0.8	0.0	1.6	0.1	0.8	1.2	1.8	0.1
Illnesses of father: None of the above (group 1)	1.3	1.6	10.2	-0.2	-0.3	-0.0	1.0	-0.5	1.4	1.1	0.1	-3.2
Smoking status: Current	0.3	0.5	3.0	0.7	0.6	-0.0	0.6	-0.2	-1.7	0.2	0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.7	10.4	-0.3	-0.4	-2.3	-3.2	-2.3	-0.3	-3.2	-3.1	1.3
Whole body water mass	0.6	3.6	10.2	2.2	2.2	0.1	3.2	0.7	1.1	1.7	2.5	-1.4
Leg predicted mass (right)	0.8	4.2	11.3	2.6	2.6	0.3	3.4	0.4	1.4	1.4	2.5	-1.4
Arm fat mass (left)	0.9	3.9	9.2	1.5	1.8	1.4	3.0	0.7	2.1	1.7	2.4	-2.2
Number of self-reported non-cancer illnesses	0.3	0.5	1.4	0.5	0.6	0.0	-0.7	-0.5	-1.0	-1.2	-0.3	-1.0
Average weekly champagne plus white wine intake	1.2	1.6	5.0	2.2	2.2	-1.5	0.2	0.1	0.2	-1.1	-0.4	-1.0
Miserableness	0.5	0.9	2.9	1.5	1.7	0.3	0.6	0.4	0.7	0.2	0.9	-1.1
Guilty feelings	1.4	2.1	5.0	-0.9	-0.6	2.2	1.3	-0.1	2.2	1.3	1.4	-1.6
Wears glasses or contact lenses	0.3	0.4	0.9	0.9	0.9	-0.6	0.5	0.1	0.6	0.4	0.1	-0.8
Ever taken oral contraceptive pill	1.5	1.7	3.8	1.3	1.6	0.7	1.9	1.7	1.2	0.9	1.2	-0.6
Hearing aid user	0.7	0.7	2.0	1.4	1.4	0.4	1.1	0.2	0.0	0.6	0.6	-0.7
Mother’s age at death	1.6	2.0	4.9	-1.9	-1.8	-0.7	-1.0	-0.5	1.3	0.1	-2.2	-1.5
Financial situation satisfaction	0.3	0.4	1.3	0.1	0.1	-1.0	0.4	-0.2	-0.4	-0.7	-1.1	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	0.0	-0.2	0.2	0.7	-0.7	0.2	0.1	-0.7	-0.9
Commuting to job workplace: Public transport	0.6	0.7	2.4	0.3	-0.2	-0.9	-0.2	-0.9	-1.6	-0.1	-0.4	1.4
Eye problems/disorders: Glaucoma	1.3	1.5	7.4	-0.1	-0.2	-0.8	-1.5	-2.7	-0.8	-1.4	-0.3	0.5
Medication: Blood pressure	0.2	0.4	1.1	0.7	0.7	0.0	0.6	-1.1	-1.0	0.1	0.8	-0.2
Pain type(s) experienced in last month: Hip pain	1.1	1.4	3.6	1.9	1.8	0.2	1.9	-0.2	-0.5	0.4	1.2	0.0
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.0	0.7	0.9	-1.0	0.7	0.7	-0.8	-0.7	0.0	-0.7
High cholesterol (Self-reported)	0.7	1.2	3.9	-1.6	-1.4	0.0	-1.2	-0.5	-0.1	-0.1	-0.8	-2.0
Medication: Bendroflumethiazide	0.4	0.7	1.6	0.5	0.7	1.1	0.8	0.9	-0.9	0.6	1.3	-0.2
Medication: Paracetamol	0.2	0.3	0.8	0.9	0.9	-0.4	0.7	0.3	-0.7	-0.1	0.2	0.2
Medication: Lisinopril	0.5	0.6	2.2	-1.5	-1.5	0.5	-0.6	-0.5	0.4	0.3	-0.1	-0.6
Medication: Atorvastatin	0.5	0.6	1.7	-0.5	-0.4	-0.4	-1.3	-0.8	-1.2	-0.8	-0.1	-0.5
Illnesses of father: High blood pressure	0.5	0.7	1.9	-1.4	-1.3	-0.0	-1.0	-0.8	0.4	0.1	-0.2	0.6
Alcohol drinker status: Never	0.4	0.5	1.4	1.2	0.8	-1.1	0.1	-0.2	-1.0	-0.5	-0.2	-0.3
Ever smoked	0.6	1.0	2.3	0.5	0.5	1.1	1.5	0.2	1.4	1.3	0.8	-0.7
Basal metabolic rate	0.7	4.0	10.8	2.0	2.1	0.4	3.3	0.8	1.5	1.9	2.6	-1.8
Leg fat percentage (left)	1.2	4.4	10.1	0.5	1.1	1.7	2.6	1.0	2.5	2.3	2.4	-3.2
Arm fat-free mass (left)	0.7	3.8	10.7	1.9	1.9	0.1	3.3	1.1	1.1	2.0	2.6	-1.7
Number of operations (self-reported)	1.5	2.3	6.7	2.5	2.6	-1.9	1.3	1.3	-0.8	-0.3	-0.1	0.0
Average weekly beer plus cider intake	0.4	0.5	2.3	0.4	0.5	0.6	1.0	0.4	0.3	0.4	0.5	-1.5
Irritability	0.1	0.2	1.0	0.3	0.5	0.2	-0.3	-0.0	-1.0	-0.5	0.4	0.1
Risk taking	0.5	0.8	2.3	0.7	0.7	0.4	0.8	1.5	0.1	1.1	0.7	-1.0
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.4	0.7	0.9	0.1	0.9	0.8	1.2	0.4	-0.3	-0.5
Fractured/broken bones in last 5 years	2.1	2.7	7.0	1.3	0.9	1.4	2.0	0.2	2.1	1.8	0.8	-2.6
Age started oral contraceptive pill	0.3	0.4	0.9	-0.1	-0.1	-0.6	-0.8	0.6	-0.9	-0.8	-0.7	-0.1
Diastolic blood pressure, automated reading	0.4	1.2	3.5	-1.9	-1.4	-1.0	-1.3	0.1	-0.9	-0.9	-0.9	0.1
Ever depressed for a whole week	0.8	0.9	2.0	1.0	0.9	0.5	0.7	-1.4	1.2	0.6	0.9	-1.2
Unable to work because of sickness or disability	0.6	0.8	2.1	0.8	1.0	0.1	1.0	-1.2	0.5	0.3	0.7	-1.4
Commuting to job workplace: Cycle	0.2	0.3	0.7	0.1	0.2	0.9	-0.2	-0.7	0.4	-0.7	-0.3	0.5
Myopia	1.8	2.6	7.1	-0.5	-0.4	1.4	1.6	2.7	0.7	2.1	2.4	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.7	-1.5	-1.6	-0.1	-0.6	-0.6	1.5	0.1	-1.2	-0.3
Cholesterol lowering medication	0.2	0.3	1.4	-0.2	-0.1	-0.6	-0.4	-0.7	-1.2	-0.6	-0.2	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.1	0.5	0.7	0.0	0.2	-1.4	0.2	-0.2	0.5	-0.3
Pain experienced in last month	0.9	1.5	3.5	-1.3	-1.6	-0.7	-1.9	-1.5	0.2	-0.6	-1.6	0.2
Supplements: Calcium	0.4	0.5	1.2	-0.7	-0.5	-0.8	-0.7	0.3	-0.8	-1.1	-0.9	0.1
Basal cell carcinoma (self-reported)	1.3	1.6	4.8	-0.4	-0.3	-1.7	-0.9	-0.5	-2.2	-1.1	-0.6	2.0
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.1	1.3	1.6	0.3	1.2	1.8	0.8	0.9	1.1	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.4	0.3	0.4	-0.0	0.3	-0.4	-1.2	-1.2	-0.9	0.5
Heart disease (siblings)	0.6	0.8	1.5	1.2	1.2	0.2	1.2	0.1	-1.0	0.0	1.0	0.7
Alcohol drinker status: Previous	0.1	0.1	0.5	0.1	0.1	-0.1	0.7	-0.2	-0.1	0.1	0.2	-0.0
Pack years of smoking	2.7	4.0	7.2	1.4	1.7	1.9	2.7	1.9	1.1	2.4	2.5	-1.7
Impedance of whole body	0.7	3.6	9.5	-3.1	-3.1	2.8	-1.7	0.8	1.2	0.9	-0.0	-0.0
Leg fat mass (left)	1.0	4.0	8.0	0.7	1.1	1.4	2.8	0.7	2.3	2.1	2.5	-2.8
Arm predicted mass (left)	0.6	3.2	8.9	1.9	2.0	-0.2	3.0	0.9	0.7	1.6	2.4	-1.5