TWAS hub - CD276

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0510	0.0200	0.0032	0.035	0.026	0.022	0.025	-0.002	3.5e-05	0.0003	0.00089	0.00046	0.730
2	TCGA	Prostate Adenocarcinoma	0.0291	0.0181	0.0042	0.006	0.017	0.015	NA	0.010	7.6e-02	0.0055	0.00830	NA	0.027

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Risk taking	8.4	12.2	17.3	-2.7	-4.2
Loud music exposure frequency	8.2	8.9	9.0	-3.0	-3.0
Exposure to tobacco smoke outside home	8.0	10.7	17.0	-4.1	-2.1
Coronary Artery Disease (CAD)	7.2	8.5	14.2	-3.8	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	5.3	8.1	10.1	-3.2	-2.5
Neuroticism (2016)	5.1	7.4	9.5	2.3	3.1
Shortness of breath walking on level ground	4.7	5.6	7.1	-2.7	-2.0
Smoking Status	4.4	10.4	10.8	-3.2	-3.3
Illnesses of mother	4.4	5.5	7.1	2.0	2.7
Hearing aid user	4.3	4.9	6.1	1.9	2.5
Current tobacco smoking	4.0	6.5	7.4	-2.7	-2.4
Falls in the last year	4.0	5.4	7.5	-2.7	-1.8
Hearing difficulty/problems with background noise	3.9	6.2	10.2	-3.2	-1.5
Age at First Birth	3.6	5.3	8.0	2.8	1.6
Depression (self-reported)	3.6	4.3	5.5	-2.4	-1.8
Waist Hip Ratio (WHR)	3.5	15.9	20.0	-4.5	-3.4
Prostate Cancer	3.4	4.8	8.5	-2.9	-1.0
Alzheimer’s Disease (including proxy)	3.3	4.7	6.0	-1.9	-2.5
Noisy workplace	3.3	4.1	4.6	-1.9	-2.1
Number of children fathered	3.2	3.6	5.0	-1.5	-2.2
Mean Putamen Volume	3.1	3.5	4.6	-1.5	-2.1
Alzheimer’s Disease (in mother)	3.0	3.5	4.7	-1.5	-2.2
BMI	3.0	17.5	19.4	-4.4	-3.9
Frequency of depressed mood in last 2 weeks	2.9	4.1	5.5	-2.4	-1.6
Wheeze or whistling in the chest in last year	2.9	5.2	8.4	-2.9	-1.4
Smoking status: Current	2.9	4.6	5.2	-2.3	-2.0
Ever smoked	2.8	4.9	5.7	-2.0	-2.4
Guilty feelings	2.7	4.0	6.3	-1.3	-2.5
Height	2.6	50.0	95.6	9.8	2.1
Medication: Ibuprofen (e.g. Nurofen)	2.6	3.3	6.3	-2.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.0	4.9	-2.2	-1.0
Diabetes (mother)	2.5	3.2	4.5	-2.1	-1.4
Past tobacco smoking	2.5	4.5	5.8	1.8	2.4
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.8	7.0	-2.7	0.8
Length of working week for main job	2.4	2.7	4.6	-2.1	-0.9
Bipolar Disorder (2018)	2.3	3.7	4.9	-1.6	2.2
Major Depression (MDD)	2.3	2.8	5.1	-2.3	-0.7
Medication: Metformin	2.3	3.3	4.3	-1.5	-2.1
Body mass index (BMI)	2.3	9.7	13.2	-3.6	-2.5
Standing height	2.2	21.7	42.6	6.5	0.8
Family relationship satisfaction	2.2	2.6	3.2	1.8	1.4
Hand grip strength (right)	2.1	5.8	11.5	3.4	-0.2
Waist circumference	2.1	7.7	8.4	-2.9	-2.7
Mouth/teeth dental problems: Loose teeth	2.1	2.4	2.9	-1.7	-1.4
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	2.7	-1.6	-1.3
Chronic bronchitis/emphysema (father)	2.0	2.3	3.2	-1.2	-1.8
Medication: Simvastatin	2.0	3.0	5.0	-1.0	-2.2
Migraine (self-reported)	2.0	2.4	2.8	-1.7	-1.4
Financial situation satisfaction	2.0	2.5	4.8	-2.2	-0.5
Number of full brothers	1.9	2.3	3.2	-1.8	-1.2
Heart disease (mother)	1.9	2.3	2.4	-1.6	-1.5
Schizophrenia vs Biploar Disorder	1.8	2.3	4.7	2.2	-0.0
Pack years adult smoking proportion	1.8	2.7	2.8	-1.6	-1.7
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	3.1	1.0	1.7
Medication: Ibuprofen	1.8	2.1	4.2	-2.1	-0.0
Smoking status: Previous	1.8	2.7	3.8	-1.3	-1.9
Diabetes diagnosed by doctor	1.8	2.9	3.0	-1.7	-1.7
Age started oral contraceptive pill	1.8	2.3	4.5	2.1	0.4
Pack years of smoking	1.8	2.7	3.0	-1.5	-1.7
Impedance of whole body	1.8	9.1	9.5	3.1	3.0
Hand grip strength (left)	1.7	4.6	8.3	2.9	-0.9
Average weekly spirits intake	1.7	2.1	3.3	-0.9	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	2.1	-1.2	-1.4
Average weekly beer plus cider intake	1.7	2.4	2.8	1.7	1.4
Financial difficulties in last 2 years	1.6	2.2	3.2	-1.8	-1.1
Impedance of arm (left)	1.6	7.5	9.1	3.0	2.4
Neck or shoulder pain in last month	1.6	2.3	3.1	-1.8	1.2
Number of full sisters	1.6	2.0	2.8	-1.7	-1.1
Fractured/broken bones in last 5 years	1.6	2.0	2.4	-1.5	-1.3
Depression (Nagel 2018)	1.5	2.2	3.2	-1.8	-1.1
Type 2 Diabetes (T2D) (2018)	1.5	2.8	2.9	-1.6	-1.7
Impedance of leg (right)	1.4	6.6	7.2	2.7	2.4
Alcohol intake versus 10 years previously	1.4	2.0	3.9	2.0	0.4
Hair/balding pattern: Pattern 3	1.4	2.1	3.6	0.8	-1.9
Overall health rating	1.4	3.0	5.7	-2.4	0.5
Average weekly champagne plus white wine intake	1.4	1.9	2.6	-1.6	-1.1
Leg fat percentage (left)	1.4	4.9	7.8	-2.8	-1.4
Bipolar Disorder or Schizophrenia	1.3	3.2	5.2	-1.1	2.3
Diabetes (self-reported)	1.3	2.0	2.3	-1.5	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	2.0	-1.4	-1.0
Heart disease (siblings)	1.3	1.6	3.0	-0.5	-1.7
Cardiovascular Disease	1.2	3.8	5.1	-1.6	-2.3
Sensitivity / hurt feelings	1.2	2.1	3.8	-1.9	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	3.1	-1.5	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.4	1.6	0.6
Comparative height size at age 10	1.2	6.6	13.2	3.6	0.2
Ever taken oral contraceptive pill	1.2	1.4	2.6	-1.6	-0.4
High cholesterol (Self-reported)	1.2	2.1	3.5	-0.9	-1.9
Unable to work because of sickness or disability	1.2	1.5	2.9	0.3	1.7
Alcohol drinker status: Previous	1.2	1.3	2.5	-1.6	-0.4
Alzheimer’s Disease (in father)	1.1	1.2	1.5	-1.0	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	2.3	-1.5	-0.7
Impedance of leg (left)	1.1	5.2	5.9	2.1	2.4
Mouth/teeth dental problems	1.1	1.7	1.7	1.3	1.3
Impedance of arm (right)	1.1	5.1	7.3	2.7	1.7
Pulse rate	1.1	1.8	3.0	0.7	1.7
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.1	-1.4	-0.8
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	3.5	0.3	1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	1.7	0.9	1.3
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	1.5	-1.1	-1.2
Rheumatoid Arthritis	1.0	1.3	2.6	-1.6	-0.2
High blood pressure (mother)	1.0	1.4	1.8	-1.0	-1.4
Number of incorrect matches in round	1.0	1.6	2.9	-0.6	1.7
Hair/balding pattern: Pattern 4	1.0	2.3	3.2	1.2	1.8
Pulse wave reflection index	1.0	1.2	1.3	-1.0	-1.1
Chronic bronchitis/emphysema (mother)	1.0	1.2	1.3	-1.1	-1.1
Leg fat percentage (right)	1.0	3.6	5.6	-2.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	2.7	1.6	1.2
Osteoporosis (self-reported)	1.0	1.3	2.5	1.6	0.3
Forced vital capacity (FVC)	0.9	3.4	6.8	2.6	0.1
Peak expiratory flow (PEF)	0.9	2.1	2.9	1.1	-1.7
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.0	-0.5	-1.4
Mineral and other dietary supplements	0.9	1.3	2.4	-1.5	-0.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	1.6	0.2
Heart attack/myocardial infarction (self-reported)	0.9	1.1	1.6	-0.8	-1.3
Fasting Glucose	0.8	1.0	1.0	-1.0	-1.0
Relative age of first facial hair	0.8	1.7	2.0	-1.2	-1.4
Happiness	0.8	0.9	1.2	1.1	0.8
Mouth/teeth dental problems: Dentures	0.8	1.4	1.9	-1.4	-0.9
Medication: Cholesterol lowering	0.8	1.2	1.3	-1.1	-1.1
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.1	-1.5	-0.2
Age at first live birth	0.8	1.5	2.4	1.5	0.8
Medication: Omeprazole	0.8	1.0	1.6	0.5	1.3
Leg pain on walking	0.8	1.0	1.6	-1.3	-0.6
Commuting to job workplace: Walk	0.8	0.9	1.6	0.4	1.3
Eye problems/disorders: Cataract	0.8	1.0	1.9	1.4	0.2
Cholesterol lowering medication	0.8	1.2	2.2	-0.4	-1.5
Reaction Time	0.7	1.4	2.8	-1.7	0.0
Bipolar Disorder (2011)	0.7	0.7	1.3	-0.4	1.1
Nervous feelings	0.7	1.3	2.2	0.6	1.5
Pain all over the body in last month	0.7	0.8	0.8	-0.9	-0.8
Arm fat percentage (right)	0.7	2.8	4.1	-2.0	-1.2
Arm fat mass (right)	0.7	2.7	2.7	-1.6	-1.7
Blood clot in the leg (DVT)	0.7	0.9	1.1	-1.0	-0.9
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	1.5	0.8	1.2
Medication: Aspirin	0.7	1.0	1.3	1.1	0.8
Arm fat percentage (left)	0.7	3.0	4.9	-2.2	-1.0
Average weekly red wine intake	0.7	1.0	2.1	-1.4	-0.0
Long-standing illness, disability or infirmity	0.7	1.0	1.6	-1.3	-0.6
Medication: Gliclazide	0.7	0.8	1.6	-0.1	-1.3
Ever depressed for a whole week	0.7	0.9	1.8	-1.3	-0.2
Leg fat mass (left)	0.7	2.8	3.0	-1.7	-1.6
Primary Biliary Cirrhosis	0.6	0.9	1.7	0.3	1.3
Schizophrenia (2014)	0.6	1.4	2.6	-0.6	1.6
Ulcerative Colitis	0.6	0.8	1.6	-1.2	0.3
Age when periods started (menarche)	0.6	1.4	1.9	1.4	0.9
Hair/balding pattern: Pattern 2	0.6	0.8	1.5	0.2	1.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.3	-1.1	0.4
Heart attack	0.6	0.8	1.2	-0.6	-1.1
Exposure to tobacco smoke at home	0.6	0.7	1.3	-0.4	1.1
Forced vital capacity (FVC), Best measure	0.6	2.2	4.0	2.0	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	0.9	-0.9	-1.0
Health satisfaction	0.6	0.8	1.1	-0.7	1.0
Medication: Blood pressure	0.6	1.0	1.2	-0.9	-1.1
Mean time to correctly identify matches	0.6	1.1	2.2	-1.5	-0.3
Leg fat mass (right)	0.6	2.2	2.3	-1.4	-1.5
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.2	-0.5	-1.1
Osteoarthritis (self-reported)	0.6	0.8	1.0	-1.0	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.2	-0.4	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.3	0.3	1.1
Medication for hormone replacement therapy	0.5	0.5	0.7	0.8	0.5
Maternal smoking around birth	0.5	0.7	1.0	-1.0	-0.6
Taking other prescription medications	0.5	0.8	0.9	-0.9	-0.9
Stomach or abdominal pain in last month	0.5	0.6	0.9	-1.0	-0.5
Supplements: Glucosamine	0.5	0.6	1.2	1.1	0.3
Medication: Levothyroxine sodium	0.5	0.9	1.0	0.9	1.0
Sitting height	0.5	3.8	6.8	2.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.7	-0.8	-1.3
Qualifications: None of the above	0.5	1.2	2.0	0.6	1.4
Trunk fat-free mass	0.5	2.6	2.9	1.5	-1.7
Asthma	0.5	1.0	1.1	-1.0	-1.0
Lung cancer (father)	0.5	0.6	0.7	0.8	0.8
Trunk predicted mass	0.5	2.7	3.0	1.5	-1.7
Medication: Paracetamol	0.5	0.9	1.3	-1.1	0.7
Body fat percentage	0.5	1.9	2.9	-1.7	-0.9
Worry too long after embarrassment	0.5	0.9	1.8	-0.0	1.4
Medication: Allopurinol	0.5	0.7	1.5	1.2	0.0
Knee pain experienced in last month	0.5	0.8	1.3	-1.1	0.5
Arm fat mass (left)	0.5	2.1	2.3	-1.5	-1.4
Miserableness	0.5	0.9	1.5	-0.6	1.2
Eye problems/disorders: Glaucoma	0.5	0.6	0.9	0.5	1.0
Medication: Paracetamol	0.5	0.8	1.3	-0.5	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.9	-1.0	-0.4
Pain experienced in last month	0.5	0.9	1.5	1.2	-0.5
HDL Cholesterol	0.4	0.6	1.2	1.1	0.3
Medication: Co-codamol	0.4	0.4	0.5	-0.6	-0.7
Medication: Atenolol	0.4	0.5	1.0	-1.0	-0.0
Medication: Ramipril	0.4	0.6	0.9	-0.4	-1.0
Fluid intelligence score	0.4	0.8	1.1	1.0	0.8
Illnesses of siblings	0.4	0.5	0.6	0.7	0.7
Weight	0.4	1.9	3.6	-0.5	-1.9
Prospective memory result	0.4	0.5	0.7	-0.5	-0.9
Tense / ‘highly strung’	0.4	0.6	1.0	0.5	1.0
Pulse wave peak to peak time	0.4	0.5	0.7	0.8	0.6
Medication for pain relief, constipation, heartburn	0.4	0.7	0.8	0.8	-0.9
Whole body fat-free mass	0.4	2.1	3.2	1.0	-1.8
Qualifications: nursing, teaching	0.4	0.6	1.1	0.1	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.3	-0.0	-1.1
Back pain experienced in last month	0.4	0.6	0.7	-0.6	-0.8
Asthma (self-reported)	0.4	0.8	0.8	-0.9	-0.9
Medication: Aspirin	0.4	0.6	1.0	1.0	0.4
Number of self-reported non-cancer illnesses	0.4	0.7	0.9	-0.6	-1.0
Arm predicted mass (left)	0.4	2.0	3.8	0.4	-2.0
Schizophrenia (2018)	0.3	0.7	1.3	-0.1	1.1
HbA1C	0.3	0.3	0.3	0.6	0.6
Blood Eosinophil Count	0.3	2.0	2.2	-1.5	-1.3
Lung FEV1/FVC ratio	0.3	1.4	2.7	-1.6	-0.3
Hearing difficulty/problems: Yes	0.3	0.5	0.9	-1.0	0.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.8	-0.9	-0.1
Vitamin and mineral supplements	0.3	0.4	0.7	0.3	0.8
Leg fat-free mass (left)	0.3	1.6	3.0	0.4	-1.7
Trunk fat percentage	0.3	1.1	1.7	-1.3	-0.7
Fed-up feelings	0.3	0.5	0.9	-0.1	1.0
Leg predicted mass (left)	0.3	1.5	2.9	0.4	-1.7
Neuroticism score	0.3	0.6	0.8	-0.7	0.9
Number of live births	0.3	0.4	0.7	0.4	0.8
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	2.2	1.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	0.9	0.9	-1.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.6	-0.3	-0.8
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.0	1.0	0.4
Eye problems/disorders: None of the above	0.3	0.4	0.8	-0.9	0.0
Medication: Seretide 50 evohaler	0.3	0.3	0.6	-0.2	-0.8
Whole body fat mass	0.3	1.4	1.7	-1.0	-1.3
Arm predicted mass (right)	0.3	1.5	2.9	0.3	-1.7
Chest pain or discomfort	0.3	0.4	0.8	-0.9	-0.2
Leg fat-free mass (right)	0.3	1.7	3.5	0.1	-1.9
Loneliness, isolation	0.3	0.4	0.5	-0.7	-0.5
Ever had bowel cancer screening	0.3	0.3	0.4	0.7	-0.4
Whole body water mass	0.3	1.9	3.0	0.9	-1.7
Leg predicted mass (right)	0.3	1.8	3.6	0.1	-1.9
Mother’s age at death	0.3	0.4	0.5	0.6	-0.7
Medication: Bendroflumethiazide	0.3	0.5	0.8	-0.9	0.3
Illnesses of father: High blood pressure	0.3	0.4	0.8	-0.1	0.9
Basal metabolic rate	0.3	1.8	3.2	0.6	-1.8
Arm fat-free mass (left)	0.3	1.6	2.9	0.6	-1.7
Myopia	0.3	0.4	0.7	-0.4	-0.8
Depressed Affect (Nagel 2018)	0.2	0.4	0.7	-0.8	-0.4
Lupus	0.2	0.2	0.4	0.2	-0.7
Heel T-Score	0.2	1.4	2.7	-0.3	-1.6
Systolic Blood Pressure	0.2	0.9	1.1	-1.1	-0.9
Lung FVC	0.2	0.8	1.6	0.3	-1.3
Number of treatments/medications taken	0.2	0.4	0.5	-0.7	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.4	-0.4	-0.6
Supplements: Zinc	0.2	0.2	0.3	0.6	-0.2
Severe depression (siblings)	0.2	0.2	0.4	-0.6	0.1
Townsend deprivation index at recruitment	0.2	0.3	0.5	-0.7	-0.3
Average weekly fortified wine intake	0.2	0.3	0.5	0.2	-0.7
Relative age voice broke	0.2	0.4	0.4	-0.6	-0.6
Serious illness, injury or assault to yourself	0.2	0.2	0.4	-0.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.3	0.4	-0.7	0.5
Multivitamins +/- minerals	0.2	0.3	0.6	-0.1	-0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.3	0.4	0.5
Trunk fat mass	0.2	1.0	1.3	-0.8	-1.2
Alcohol usually taken with meals	0.2	0.4	0.5	-0.6	-0.7
Had menopause	0.2	0.2	0.4	-0.2	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.3	-0.5	-0.5
Hip circumference	0.2	1.0	1.8	-0.3	-1.4
Father’s age at death	0.2	0.3	0.5	-0.4	-0.7
Breastfed as a baby	0.2	0.2	0.4	0.6	-0.2
Gout (self-reported)	0.2	0.2	0.5	0.7	0.1
Arm fat-free mass (right)	0.2	1.3	2.4	0.4	-1.5
Comparative body size at age 10	0.2	0.5	1.0	-1.0	-0.2
Qualifications: College or University degree	0.2	0.5	0.8	0.4	-0.9
Suffer from ‘nerves’	0.2	0.4	0.6	-0.7	0.5
Supplements: Vitamin C	0.2	0.3	0.5	0.0	0.7
Illnesses of father: Heart disease	0.2	0.3	0.5	-0.1	0.7
Illnesses of siblings: Diabetes	0.2	0.3	0.3	0.5	-0.5
Friendships satisfaction	0.2	0.2	0.3	0.5	0.3
Medication for cholesterol	0.2	0.3	0.3	-0.6	-0.4
Breast cancer (self-reported)	0.2	0.2	0.3	-0.5	-0.5
Illnesses of father: None of the above (group 1)	0.2	0.2	0.4	0.7	0.1
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.4	0.6
Medication: Blood pressure	0.2	0.4	0.5	0.7	0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	0.1	0.7
Irritability	0.2	0.4	0.7	-0.8	0.2
Diastolic blood pressure, automated reading	0.2	0.7	0.7	-0.8	-0.8
Supplements: Calcium	0.2	0.2	0.4	0.1	-0.7
Neuroticism (Nagel 2018)	0.1	0.2	0.4	-0.7	-0.2
Crohns Disease (2017)	0.1	0.2	0.4	0.2	0.6
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	0.6	0.2
Breast Cancer	0.1	0.3	0.4	0.6	0.3
Ovarian Cancer	0.1	0.1	0.2	0.5	-0.1
Body Mass Index (BMI) (2010)	0.1	0.1	0.1	0.3	-0.4
LDL Cholesterol	0.1	0.1	0.1	0.3	0.3
Blood Red Count	0.1	1.4	2.8	0.2	1.7
Blood White Count	0.1	0.8	1.3	-1.1	-0.5
Allergy or Eczema	0.1	0.1	0.2	-0.4	0.3
Hypothyroidism (self reported)	0.1	0.2	0.3	0.3	0.6
Respiratory disease	0.1	0.2	0.4	-0.1	-0.6
Neuroticism	0.1	0.3	0.5	0.0	0.7
Tanning	0.1	0.8	0.9	-0.9	-0.9
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	0.5	0.2
Diabetes (father)	0.1	0.1	0.2	0.4	0.2
High blood pressure	0.1	0.2	0.3	-0.2	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.3	-0.3	0.5
Had other major operations	0.1	0.1	0.2	-0.2	0.4
Allergy	0.1	0.2	0.4	0.6	-0.3
Worrier / anxious feelings	0.1	0.2	0.4	-0.6	-0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.2	-0.5	0.2
Medication: Lansoprazole	0.1	0.2	0.3	-0.5	-0.1
Pulse wave Arterial Stiffness index	0.1	0.2	0.2	-0.4	-0.4
Birth weight of first child	0.1	0.3	0.3	0.5	-0.5
Glaucoma (self-reported)	0.1	0.1	0.1	0.3	0.3
Medication: Amlodipine	0.1	0.1	0.1	0.3	-0.3
High blood pressure (siblings)	0.1	0.2	0.3	-0.6	0.2
Age at last live birth	0.1	0.1	0.2	0.5	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.1	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.0	-0.4
Mood swings	0.1	0.2	0.3	-0.3	-0.6
Wears glasses or contact lenses	0.1	0.1	0.2	-0.3	0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	-0.1	0.5
Medication: Lisinopril	0.1	0.2	0.4	0.1	-0.6
Medication: Atorvastatin	0.1	0.1	0.1	0.3	0.3
Alcohol drinker status: Never	0.1	0.1	0.2	-0.4	-0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	0.1	0.4
Worry (Nagel 2018)	0.0	0.1	0.1	0.0	0.4
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	-0.3	0.1
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.1	0.2
Crohns Disease (2012)	0.0	0.0	0.1	0.2	0.2
Triglycerides	0.0	0.0	0.0	0.1	-0.1
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	-0.2	0.0
Blood Platelet Count	0.0	0.2	0.3	-0.6	-0.1
Chronotype (morning person)	0.0	0.0	0.0	0.2	-0.1
Hair Pigment	0.0	0.8	1.6	-1.3	-0.2
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	0.2	0.1
Systolic blood pressure, automated reading	0.0	0.0	0.1	-0.1	-0.3
Angina	0.0	0.0	0.0	0.2	-0.1
Qualifications: CSEs or equivalent	0.0	0.1	0.1	-0.3	-0.2
Time employed in main current job	0.0	0.0	0.1	-0.3	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.0	0.1	-0.0
Headache pain in last month	0.0	0.1	0.1	-0.1	0.4
Birth weight	0.0	0.0	0.0	-0.0	0.0
Emphysema/chronic bronchitis	0.0	0.1	0.1	-0.3	0.1
Angina (self-reported)	0.0	0.1	0.1	0.1	-0.3
Pulse rate, automated reading	0.0	0.1	0.1	-0.3	0.2
Alcohol intake frequency.	0.0	0.1	0.1	-0.3	-0.3
Had major operations	0.0	0.0	0.0	0.1	0.0
Hypertension (Self-reported)	0.0	0.1	0.2	0.0	-0.5
Number of operations (self-reported)	0.0	0.0	0.1	0.2	0.2
Commuting to job workplace: Cycle	0.0	0.0	0.1	0.3	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	-0.0	0.5
Basal cell carcinoma (self-reported)	0.0	0.0	0.1	0.3	-0.1

Hub : Genes

CD276

Models

Trait associations