Hub : Genes

CDA

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2420 0.0470 1.1e-09 0.133 NA 0.177 NA 0.212 5.2e-11 NA 2.4e-14 NA 3.0e-17
2 GTEx Adipose Visceral Omentum 0.3000 0.0660 6.1e-06 0.025 NA 0.089 NA 0.045 1.9e-02 NA 2.3e-05 NA 2.2e-03
3 GTEx Adrenal Gland 0.2393 0.0850 7.0e-03 0.038 NA 0.021 NA 0.053 1.7e-02 NA 5.9e-02 NA 5.6e-03
4 GTEx Artery Aorta 0.1920 0.0640 1.4e-03 0.061 NA 0.090 NA 0.072 2.9e-04 NA 1.2e-05 NA 8.2e-05
5 GTEx Artery Tibial 0.1834 0.0450 3.0e-06 0.043 NA 0.089 NA 0.094 2.8e-04 NA 1.9e-07 NA 8.2e-08
6 GTEx Brain Cerebellum 0.3160 0.1130 8.7e-03 -0.010 NA -0.010 NA -0.007 9.7e-01 NA 9.9e-01 NA 6.0e-01
7 GTEx Breast Mammary Tissue 0.2510 0.0610 4.3e-06 0.123 NA 0.179 NA 0.195 7.6e-07 NA 1.6e-09 NA 2.6e-10
8 GTEx Breast Mammary Tissue (Male) 0.2310 0.0976 1.1e-02 0.001 NA -0.012 NA -0.013 3.1e-01 NA 7.8e-01 NA 8.9e-01
9 GTEx Breast Mammary Tissue (Female) 0.2493 0.0914 6.5e-03 0.138 NA 0.139 NA 0.209 6.8e-05 NA 6.0e-05 NA 7.3e-07
10 GTEx Cells Transformed fibroblasts 0.3030 0.0530 4.6e-11 0.089 NA 0.156 NA 0.173 3.3e-07 NA 9.4e-12 NA 5.3e-13
11 GTEx Esophagus Muscularis 0.2040 0.0500 6.1e-06 0.153 NA 0.129 NA 0.144 1.4e-09 NA 3.0e-08 NA 4.6e-09
12 GTEx Heart Atrial Appendage 0.2030 0.0740 4.9e-03 0.029 NA 0.032 NA 0.026 1.8e-02 NA 1.4e-02 NA 2.4e-02
13 GTEx Heart Left Ventricle 0.1751 0.0537 1.0e-03 0.101 NA 0.093 NA 0.068 5.2e-06 NA 1.2e-05 NA 1.7e-04
14 GTEx Muscle Skeletal 0.1700 0.0377 3.4e-08 0.117 NA 0.136 NA 0.151 1.5e-11 NA 3.2e-13 NA 1.3e-14
15 GTEx Nerve Tibial 0.4229 0.0562 0.0e+00 0.305 NA 0.318 NA 0.358 5.1e-22 NA 4.8e-23 NA 2.3e-26
16 GTEx Skin Sun Exposed Lower leg 0.1360 0.0430 2.9e-04 0.051 NA 0.065 NA 0.059 4.5e-05 NA 4.2e-06 NA 1.1e-05
17 GTEx Small Intestine Terminal Ileum 0.3800 0.1120 3.7e-03 0.308 NA 0.148 NA 0.289 1.2e-07 NA 3.6e-04 NA 3.3e-07
18 GTEx Testis 0.3530 0.0750 3.3e-06 0.186 NA 0.155 NA 0.203 1.1e-08 NA 2.2e-07 NA 2.3e-09
19 GTEx Thyroid 0.2420 0.0430 1.0e-11 0.115 NA 0.252 NA 0.255 4.2e-09 NA 2.9e-19 NA 1.4e-19
20 GTEx Whole Blood 0.1940 0.0390 1.8e-08 0.204 NA 0.165 NA 0.204 1.6e-18 NA 5.2e-15 NA 1.4e-18
21 METSIM Adipose 0.1098 0.0259 1.1e-09 0.089 0.084 0.109 0.099 0.112 3.0e-13 1.6e-12 4.9e-16 1.3e-14 2.5e-16
22 NTR Blood 0.0902 0.0162 0.0e+00 0.102 0.073 0.091 0.099 0.103 5.3e-31 1.6e-22 1.1e-27 3.8e-30 2.6e-31
23 ROSMAP Brain Pre-frontal Cortex 0.2552 0.0376 0.0e+00 0.222 0.239 0.234 0.244 0.244 4.6e-28 2.2e-30 1.3e-29 5.3e-31 4.2e-31
24 YFS Blood 0.3216 0.0310 0.0e+00 0.311 0.382 0.406 0.402 0.401 1.9e-104 2.9e-134 7.8e-145 3.9e-143 1.6e-142
25 TCGA Breast Invasive Carcinoma 0.1616 0.0388 0.0e+00 0.037 0.141 0.130 NA 0.124 4.3e-08 1.1e-27 1.2e-25 NA 1.8e-24
26 TCGA Colon Adenocarcinoma 0.1570 0.0510 8.1e-07 0.115 0.091 0.098 NA 0.094 3.5e-07 6.3e-06 2.6e-06 NA 4.2e-06
27 TCGA Kidney Renal Clear Cell Carcinoma 0.1743 0.0488 1.6e-13 0.113 0.142 0.124 NA 0.104 1.1e-12 1.1e-15 8.1e-14 NA 1.1e-11
28 TCGA Kidney Renal Papillary Cell Carcinoma 0.0750 0.0330 5.2e-04 0.038 0.078 0.062 NA 0.043 3.0e-03 3.0e-05 1.9e-04 NA 1.8e-03
29 TCGA Brain Lower Grade Glioma 0.2255 0.0489 0.0e+00 0.183 0.235 0.235 NA 0.224 2.6e-20 2.6e-26 2.3e-26 NA 5.1e-25
30 TCGA Pheochromocytoma and Paraganglioma 0.1070 0.0520 7.0e-03 0.030 0.046 0.042 NA 0.049 2.3e-02 6.5e-03 9.2e-03 NA 5.0e-03
31 TCGA Prostate Adenocarcinoma 0.2405 0.0569 0.0e+00 0.065 0.201 0.206 NA 0.191 2.2e-07 1.1e-20 3.8e-21 NA 1.3e-19
32 TCGA Rectum Adenocarcinoma 0.4060 0.1380 8.8e-04 0.087 0.129 0.194 NA 0.182 4.5e-03 6.3e-04 2.6e-05 NA 4.6e-05
33 TCGA Soft Tissue Sarcoma 0.0690 0.0370 5.2e-03 0.010 0.022 0.018 NA 0.000 7.9e-02 1.8e-02 3.0e-02 NA 3.0e-01
34 TCGA Thyroid Carcinoma 0.2710 0.0660 2.2e-16 0.090 0.178 0.197 NA 0.172 4.6e-09 5.0e-17 6.8e-19 NA 1.6e-16

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34
Bipolar Disorder (2018) 0.1 0.2 0.9 0.2 -0.2 -0.2 0.3 0.4 -0.9 0.0 -0.4 0.0 -0.0 0.2 0.3 0.6 0.4 -0.2 0.2 -0.3 0.3 0.3 -0.4 -0.3 -0.4 0.3 -0.4 0.4 -0.3 0.0 -0.9 -0.1 -0.2 -0.1 -0.5 -0.6 0.7
Bipolar Disorder or Schizophrenia 0.1 0.2 0.9 -0.3 -0.6 -0.2 0.1 0.7 -0.6 0.2 -0.8 0.2 -0.4 -0.1 0.4 0.6 -0.0 0.3 0.2 -0.4 0.1 0.1 -0.2 -0.5 -0.2 0.4 -0.5 0.5 -0.4 0.2 -0.9 -0.3 0.0 0.1 -0.1 -0.3 -0.6
Depressed Affect (Nagel 2018) 0.5 1.0 6.7 -0.6 0.3 -0.1 -0.0 -0.6 -1.5 -0.5 -2.6 -0.5 -0.6 -1.5 0.5 -1.2 -1.1 -1.1 1.1 0.7 0.1 -0.8 1.1 0.9 1.0 -1.4 1.2 -0.6 0.3 0.1 -0.9 -1.1 -0.1 -0.1 1.6 -1.6 -0.9
Depression (Nagel 2018) 1.5 2.2 7.7 -1.7 -0.8 -0.5 -1.7 -1.8 -1.0 -1.5 -2.3 -1.5 -0.9 -2.8 -1.2 -2.3 -2.2 -2.0 1.9 0.4 -0.8 -1.9 0.8 0.1 0.6 -2.3 1.0 -1.7 -0.2 -0.6 -1.5 -1.2 -0.5 -0.6 1.2 -1.8 -1.7
Intelligence (Savage-Jansen 2018) 0.3 1.0 6.4 -0.3 0.2 -0.6 0.3 0.2 0.3 -0.1 0.7 -0.1 -0.6 1.8 -0.4 0.9 0.1 1.3 -0.9 -1.1 -1.2 0.4 -1.4 -1.2 -1.2 1.5 -1.6 -0.8 -1.3 -1.0 1.2 0.6 -0.5 -0.7 -2.5 1.7 0.4
Neuroticism (Nagel 2018) 0.3 0.8 13.7 -0.0 0.8 -0.4 -0.0 0.4 -1.4 0.2 -3.7 0.3 -0.4 -1.0 0.4 -0.0 -0.3 -0.1 1.0 0.9 0.1 -0.2 0.1 0.3 -0.1 -0.3 0.2 0.3 0.2 0.6 -1.2 -0.3 0.1 0.8 1.2 -0.9 -0.8
Schizophrenia (2018) 0.1 0.2 1.8 -0.5 -0.6 -0.1 -0.2 0.5 -0.1 0.3 -0.7 0.3 -0.5 -0.3 0.3 0.2 -0.4 0.6 0.1 -0.3 -0.1 -0.2 0.1 -0.3 0.1 0.2 -0.3 0.3 -0.2 0.2 -0.4 -0.3 0.2 0.2 0.2 0.2 -1.3
Schizophrenia vs Biploar Disorder 0.2 0.3 1.2 0.2 -0.9 0.7 -0.4 -0.0 0.8 0.1 -0.4 0.1 -0.0 0.0 0.4 -0.4 -0.2 0.2 -1.1 0.2 0.2 0.1 0.6 0.4 0.7 -0.3 0.6 0.2 0.5 0.0 1.0 0.4 0.3 0.5 0.6 0.2 -1.0
Worry (Nagel 2018) 0.3 0.7 10.8 -0.1 0.8 -0.2 -0.1 -0.1 -0.8 -0.0 -3.3 -0.0 -0.1 -1.0 0.7 -0.2 -0.1 -0.6 0.1 1.0 -0.0 -0.3 0.4 0.6 0.4 -0.7 0.7 -0.0 0.2 0.0 -1.1 -0.5 -0.4 0.5 1.4 -1.1 -0.7
Alzheimer’s Disease (in mother) 0.3 0.3 4.0 0.4 -0.4 0.3 2.0 0.4 1.3 0.7 -0.4 0.7 -0.4 0.3 1.0 0.6 0.6 0.5 -0.5 0.7 0.5 0.3 -0.4 0.3 -0.3 0.1 -0.3 0.2 -0.1 0.3 -0.3 -0.2 -0.2 -0.0 -0.5 0.0 0.0
Alzheimer’s Disease (in father) 4.0 4.4 12.7 2.3 0.7 2.4 -0.2 2.2 0.4 2.4 0.7 2.4 2.7 0.9 1.7 0.6 1.5 1.6 -1.5 2.5 2.6 2.2 1.7 2.7 1.4 1.4 1.9 1.7 3.1 2.4 2.0 2.3 3.2 2.4 3.6 1.8 2.4
Alzheimer’s Disease (including proxy) 1.7 2.5 5.2 1.8 0.5 1.4 1.8 2.2 1.2 2.3 -0.1 2.3 1.2 1.4 1.6 1.6 1.8 1.9 -1.4 1.9 2.2 2.0 0.3 1.5 0.3 1.6 0.5 1.5 1.6 1.9 0.9 1.5 1.7 1.7 1.5 1.2 1.8
Crohns Disease (2017) 0.2 0.5 2.0 -0.8 -0.8 -0.3 -0.8 -0.7 1.2 -0.8 1.4 -0.9 -0.7 0.2 -0.2 -0.6 -0.6 -0.2 -0.9 -0.8 -0.4 -0.4 0.3 0.0 0.6 -0.2 -0.2 -1.2 -0.6 -1.1 0.5 -0.4 -0.6 -0.5 -0.2 -0.1 -0.7
Irritable Bowel Disease (IBD) 0.2 0.4 2.0 -0.1 -1.3 0.7 0.2 -0.5 1.3 0.2 1.0 0.1 -0.2 0.4 0.7 -0.2 0.0 0.0 -1.4 0.5 0.5 0.2 0.9 0.4 1.2 -0.1 0.5 -0.2 0.3 -0.1 1.0 -0.1 0.4 0.3 -0.1 0.3 -0.1
Ulcerative Colitis (UC) 0.1 0.2 2.1 0.1 -1.4 0.5 0.5 -0.3 0.7 0.5 -0.2 0.5 -0.3 0.3 0.5 0.1 0.2 0.2 -0.6 0.7 0.7 0.4 0.5 0.1 0.7 0.1 0.3 0.1 0.3 0.3 0.4 -0.0 0.5 0.3 -0.3 0.2 -0.1
Major Depression (MDD) 0.9 1.1 4.8 -1.2 -1.2 0.1 -2.2 -1.0 -0.3 -0.9 -0.2 -0.9 -1.7 -0.6 -0.2 -1.2 -1.8 -0.3 -0.2 -0.8 -0.2 -1.0 1.1 0.2 1.2 -0.6 0.1 -1.7 -0.8 -1.4 0.1 -1.0 -0.3 -1.6 -0.2 -0.1 -2.0
Reaction Time 0.6 1.2 5.4 -0.9 -0.8 -0.1 -1.0 -1.0 -2.3 -0.9 -0.6 -0.9 -0.0 -2.1 -0.1 -1.4 -0.8 -1.7 0.7 -0.3 -0.1 -1.2 0.3 0.3 0.2 -1.9 0.2 -0.4 -0.1 -0.6 -1.6 -1.2 -1.0 -1.1 0.5 -2.2 -1.0
Verbal and Numeric Reasoning (VNR) 0.5 1.1 6.4 0.1 -0.4 -0.1 1.5 0.5 1.1 0.3 0.4 0.3 -0.6 2.1 -0.0 1.0 0.3 1.5 -1.4 -0.4 -0.7 0.7 -0.8 -0.8 -0.6 1.7 -1.0 -0.8 -0.9 -0.6 1.9 0.5 -0.1 -0.2 -1.7 2.5 1.0
Breast Cancer 0.4 0.9 3.8 0.6 0.4 -0.3 -0.1 0.5 0.6 0.7 -0.3 0.7 0.2 1.8 0.0 1.2 0.8 1.1 -0.3 0.8 -0.1 1.1 -1.5 -0.9 -1.5 1.4 -1.5 1.2 -0.0 0.6 1.0 2.0 0.5 1.1 -0.9 1.4 0.9
Ovarian Cancer 0.8 1.0 3.9 0.1 0.1 -1.0 1.9 1.2 -1.4 -0.0 0.4 -0.0 -1.1 1.8 0.4 2.0 0.6 1.1 0.4 -1.2 -0.0 0.3 -1.5 -1.1 -1.3 1.2 -1.5 0.6 -1.4 0.5 -0.4 -0.1 -0.4 0.2 -1.7 0.7 0.3
Prostate Cancer 0.8 1.1 2.9 -1.2 0.4 -1.1 -1.1 -0.1 0.5 -1.0 0.4 -1.0 -1.0 -0.5 -1.7 -0.5 -0.7 -0.1 0.6 -1.0 -1.4 -0.6 -1.4 -1.1 -1.4 0.0 -1.5 -1.4 -1.5 -1.2 -1.4 -0.3 -1.4 -1.1 -1.5 -0.5 -1.2
Age at First Birth 0.2 0.2 0.8 0.1 0.5 0.2 0.3 0.2 0.3 0.0 0.1 0.0 0.8 -0.7 0.8 -0.1 0.2 -0.6 0.4 0.5 0.5 -0.1 0.5 0.9 0.5 -0.5 0.7 0.3 0.5 0.2 -0.2 -0.4 -0.2 -0.1 0.9 -0.4 0.5
Bipolar Disorder (2011) 1.8 1.8 4.7 -1.9 -0.9 -1.5 -1.4 -1.3 -0.3 -1.4 -0.5 -1.4 -1.1 -1.2 -1.3 -1.4 -1.6 -1.2 1.1 -1.4 -1.7 -1.4 0.3 -0.9 0.4 -1.1 -0.5 -2.1 -1.4 -2.0 -1.0 -1.6 -1.6 -2.2 -1.3 -1.0 -1.1
Body Mass Index (BMI) (2010) 0.3 0.4 2.1 -0.8 -0.1 -0.1 -1.4 -0.1 0.6 -0.0 -0.2 -0.0 0.0 -1.0 -0.8 -1.1 -0.6 -0.3 0.3 0.1 -0.1 -0.1 -0.0 -0.2 -0.0 -0.4 -0.1 -1.2 0.1 -1.0 -0.9 -0.2 -0.0 -0.9 0.8 -1.2 -0.8
Coronary Artery Disease (CAD) 3.9 4.6 10.8 3.0 0.6 2.2 1.3 2.7 0.2 2.6 1.3 2.6 2.5 2.2 2.2 2.5 3.1 2.2 -1.8 1.4 1.9 2.9 -0.0 1.8 -0.1 2.3 0.8 3.0 2.2 2.2 1.6 2.5 2.1 2.9 1.6 1.3 3.3
Crohns Disease (2012) 1.1 1.7 6.5 -1.4 -0.2 -0.9 -0.2 -1.9 0.9 -1.6 0.2 -1.7 -0.7 -1.3 -0.3 -0.9 -0.8 -1.4 -0.1 -1.4 -1.5 -1.3 0.4 -0.3 0.8 -1.5 -0.1 -2.2 -1.1 -2.3 -0.6 -1.5 -1.9 -1.8 -0.7 -1.6 -2.5
Mean Putamen Volume 0.8 0.9 3.0 -0.8 -1.4 -0.9 -0.4 -1.7 -0.8 -1.2 -0.8 -1.2 -0.7 -1.0 -0.9 -1.1 -1.2 -1.2 1.1 -0.8 -0.4 -1.4 0.4 -0.7 0.3 -1.2 0.2 -0.6 -0.6 -1.0 -0.8 -1.0 -0.8 -1.0 -0.2 -0.6 -0.8
Fasting Glucose 0.5 0.7 3.1 -0.5 0.8 -0.8 -0.1 0.0 1.0 -0.6 -1.5 -0.6 -1.1 0.8 -0.1 0.6 -0.0 0.4 0.3 -0.5 -0.6 -0.2 -1.4 -1.1 -1.3 0.4 -1.3 0.0 -1.3 -0.5 -0.5 0.3 -0.3 -0.8 -1.7 -0.5 -0.5
HbA1C 0.9 1.0 3.1 1.0 0.7 0.8 1.2 1.6 0.0 1.3 0.1 1.3 0.4 1.1 1.0 1.0 0.9 1.5 -0.9 0.6 1.2 1.2 0.1 0.5 0.2 1.1 0.1 1.6 0.9 1.1 0.9 1.0 1.3 1.8 0.8 1.0 0.8
HDL Cholesterol 3.5 5.9 13.7 -2.9 -1.3 -2.8 -1.1 -2.4 -0.8 -2.9 -0.3 -2.8 -2.7 -2.3 -2.9 -1.4 -2.6 -2.3 2.5 -3.4 -2.3 -2.9 -1.3 -2.6 -1.3 -1.9 -1.9 -2.7 -2.9 -2.5 -2.7 -2.5 -2.9 -3.1 -2.0 -2.0 -3.7
LDL Cholesterol 0.5 0.8 2.6 0.8 -0.3 0.9 -0.3 0.7 0.8 0.8 -0.1 0.8 1.3 0.5 0.5 0.2 0.6 0.8 -0.8 0.9 1.4 1.0 0.6 1.1 0.6 0.7 1.0 0.3 1.3 0.4 1.6 0.7 1.6 0.7 1.3 0.9 0.5
Lupus 0.1 0.2 1.2 0.5 0.0 0.2 0.1 -0.1 0.3 -0.3 0.3 -0.3 0.4 -0.5 0.4 0.0 0.6 -0.7 0.5 0.4 0.2 0.0 0.2 -0.0 0.2 -0.6 0.3 0.7 0.3 0.4 -0.8 -0.3 -0.2 0.5 0.8 -1.1 -0.4
Neuroticism (2016) 0.7 1.0 7.1 0.7 -0.7 0.6 1.3 0.0 -0.7 0.5 -2.7 0.5 0.6 0.2 1.8 0.4 0.2 -0.2 0.1 0.9 1.3 0.3 1.2 0.9 1.2 -0.3 1.1 1.4 1.0 1.7 0.6 0.1 0.7 1.2 1.7 0.2 0.9
Primary Biliary Cirrhosis 6.1 8.7 17.4 -3.4 -1.3 -2.4 -2.5 -3.2 -0.5 -3.1 -4.2 -3.0 -2.4 -4.2 -2.9 -3.5 -3.6 -3.5 3.4 -1.6 -2.5 -3.7 0.1 -1.6 -0.2 -3.6 -0.4 -3.2 -2.0 -3.2 -3.5 -4.0 -2.7 -4.1 -0.2 -3.8 -3.6
Rheumatoid Arthritis 0.8 1.1 4.4 1.1 -2.1 1.6 1.1 0.1 -0.0 1.1 0.7 1.1 0.9 -0.1 0.7 -0.2 0.4 0.5 -1.1 1.6 1.0 0.7 1.2 1.5 1.1 0.1 1.3 0.6 1.4 0.9 1.9 0.7 1.1 0.6 0.6 1.1 0.2
Schizophrenia (2014) 0.6 1.4 4.4 -1.7 -1.4 -1.3 -0.2 -0.9 -0.5 -1.3 -1.5 -1.3 -1.5 -1.1 -0.5 -0.9 -1.6 -1.0 1.4 -1.2 -1.2 -1.5 -0.2 -1.5 -0.1 -1.2 -0.5 -0.8 -1.2 -1.1 -1.3 -1.6 -1.0 -1.0 -0.9 -1.2 -2.1
Triglycerides 0.5 0.8 3.2 0.6 0.9 0.4 -0.6 1.0 1.2 0.8 -1.2 0.8 1.0 0.7 -0.9 -0.0 0.4 1.2 0.0 0.6 0.5 1.0 -0.8 0.0 -1.0 1.2 -0.4 0.0 0.9 0.3 0.9 1.6 1.5 0.8 0.8 1.4 1.8
Type 2 Diabetes (T2D) (2012) 1.2 1.4 5.2 -1.4 -0.9 -1.7 -0.3 -1.0 -0.5 -1.6 -0.5 -1.6 -1.6 0.0 -1.0 -0.3 -1.0 -0.8 0.5 -1.7 -1.0 -1.2 -0.6 -1.5 -0.3 -0.4 -0.9 -0.9 -1.7 -1.3 -1.3 -1.0 -1.2 -0.6 -1.3 -1.7 -2.3
Ulcerative Colitis 0.6 0.8 2.4 -0.8 -1.5 -0.1 0.3 -1.6 0.4 -0.8 -0.8 -0.8 -0.5 -1.3 0.4 -0.9 -0.7 -1.4 -0.0 0.5 -0.4 -0.8 0.7 -0.6 0.9 -1.5 0.4 -0.6 -0.1 -1.1 -0.3 -1.3 -0.6 -0.9 -0.8 -1.3 -1.5
Blood Eosinophil Count 0.3 2.5 13.9 -1.5 -2.1 -1.8 -1.9 -1.3 -2.6 -1.1 -3.7 -1.1 -1.1 -1.5 -1.8 -1.6 -1.8 -0.9 2.5 -1.3 -1.1 -1.5 -0.2 -1.2 -0.4 -1.1 -1.2 -1.9 -0.8 -1.3 -1.6 -1.4 -0.8 -2.0 0.8 -0.8 -1.3
Blood Platelet Count 0.9 10.0 29.1 -2.8 -0.8 -2.7 -4.0 -1.8 2.4 -2.6 -2.3 -2.6 -5.0 0.5 -4.8 -1.3 -2.0 0.4 1.1 -3.9 -4.1 -1.8 -4.4 -5.0 -4.6 0.5 -5.4 -4.0 -4.5 -4.5 -1.1 -0.6 -1.8 -3.6 -3.9 0.5 -2.5
Blood Red Count 3.3 31.9 59.4 -6.7 -6.5 -6.1 -4.5 -5.4 -1.6 -6.2 -6.1 -6.1 -5.8 -4.3 -7.7 -4.9 -5.8 -4.5 5.3 -4.7 -6.2 -6.2 -3.8 -7.0 -3.7 -4.5 -4.9 -6.4 -5.9 -7.3 -5.6 -5.4 -6.0 -7.2 -4.3 -5.3 -5.6
Blood White Count 0.1 0.8 4.1 -0.0 -1.9 1.2 -0.7 -0.0 1.0 0.1 -0.2 0.1 -0.9 0.0 -1.0 -2.0 -1.3 0.2 -0.7 1.0 0.5 -0.1 0.8 0.4 0.5 -0.3 0.2 -1.3 1.0 -0.2 1.4 0.2 1.8 -0.2 1.3 0.6 1.1
Heel T-Score 0.5 3.8 20.6 1.6 -1.3 2.5 0.4 0.4 -0.6 1.5 2.2 1.5 3.4 -1.4 1.3 -0.6 1.2 -0.2 -0.8 2.0 2.9 1.0 2.6 3.0 2.5 -0.6 3.1 1.5 3.3 2.0 0.8 0.6 1.7 1.4 4.5 -0.3 1.5
BMI 0.4 2.3 6.1 -1.6 -1.2 -1.4 -1.4 -1.3 -2.0 -1.3 -1.0 -1.3 -1.6 -1.4 -1.8 -1.8 -1.6 -1.3 1.9 -1.1 -1.5 -1.5 -0.4 -1.7 -0.5 -1.3 -1.1 -2.3 -1.0 -1.8 -2.0 -1.7 -1.1 -1.9 0.7 -2.5 -1.3
Height 0.3 6.4 30.9 2.3 4.0 1.9 1.9 0.1 -2.6 0.4 5.6 0.3 4.3 -1.5 3.4 0.7 2.3 -2.1 -2.2 2.8 2.6 0.8 2.4 2.9 2.5 -1.8 3.3 3.4 3.2 2.1 -0.2 -0.2 0.7 2.7 4.1 -1.8 0.5
Waist Hip Ratio (WHR) 0.4 2.0 6.7 -1.3 -2.6 -1.1 -1.6 -0.8 -0.7 -1.4 -2.1 -1.4 -1.2 -0.5 -2.5 -1.1 -0.4 -0.6 1.0 -1.7 -1.1 -1.1 -1.5 -1.6 -1.5 -0.6 -1.6 -1.1 -1.6 -2.1 -2.0 -0.6 -1.5 -1.0 -0.0 -1.9 -0.6
Systolic Blood Pressure 0.3 1.3 12.6 -0.6 -3.5 0.8 -0.3 -0.9 1.0 -0.5 -0.4 -0.5 -0.5 -0.5 -0.8 -1.4 -1.1 -0.2 -1.0 0.1 0.2 -0.7 2.0 1.0 2.0 -0.6 1.2 -2.0 0.1 -1.4 1.6 -0.8 0.3 -1.5 0.0 1.0 -0.2
Smoking Status 0.2 0.6 2.9 0.1 0.7 -0.1 0.5 0.9 0.8 0.2 1.7 0.2 -1.0 0.8 -0.0 0.4 0.2 0.6 -0.1 0.1 0.7 0.1 -1.6 -1.1 -1.6 0.4 -1.6 0.3 -0.2 0.5 -0.6 0.4 0.7 0.2 -0.7 -0.6 0.7
Allergy or Eczema 0.4 1.1 4.1 -1.1 1.7 -1.3 -0.5 -1.2 -0.4 -0.8 -1.6 -0.8 -0.7 -0.7 -0.6 -0.7 -0.8 -0.9 0.9 0.0 -2.0 -0.7 -1.3 -1.6 -1.3 -0.8 -1.0 -1.3 -0.8 -1.4 -0.8 -0.7 -1.4 -0.9 -0.2 -1.4 -1.0
Cardiovascular Disease 0.2 0.8 6.2 0.1 -2.5 0.9 0.6 -0.5 -0.0 0.3 -1.3 0.3 0.8 -0.6 0.0 -1.1 -0.3 -0.3 -0.2 1.2 1.2 -0.0 1.4 0.9 1.2 -0.4 1.2 -1.2 1.1 0.0 1.0 0.1 1.0 -0.8 0.4 0.7 0.5
Hypothyroidism (self reported) 2.2 5.0 12.1 3.0 1.5 1.9 2.4 2.4 -0.0 2.5 0.2 2.5 3.5 1.4 2.6 2.5 2.9 1.9 -0.9 2.1 2.9 2.5 1.0 2.4 0.9 1.9 1.2 2.9 2.8 2.8 1.2 2.0 2.5 2.0 2.5 1.6 3.3
Respiratory disease 0.9 2.0 3.8 -1.4 -0.9 -1.6 -0.8 -1.8 -2.0 -1.7 -0.3 -1.7 -1.3 -1.3 -1.6 -0.8 -1.2 -1.0 1.7 -1.6 -1.6 -1.9 -1.1 -1.5 -1.0 -1.3 -1.1 -1.6 -1.4 -1.8 -1.5 -1.4 -1.6 -1.6 0.1 -1.5 -1.1
Type 2 Diabetes (T2D) (2018) 0.3 0.5 2.3 0.1 0.3 0.1 0.0 0.8 0.4 0.3 -0.6 0.3 0.1 0.9 -0.5 0.7 0.7 0.9 0.9 0.4 0.4 0.7 -1.4 -1.0 -1.5 0.9 -1.3 0.9 -0.3 0.3 -0.2 0.7 0.4 0.1 -0.5 0.1 1.1
Lung FEV1/FVC ratio 0.2 1.1 3.4 -0.5 -1.1 -1.1 -0.9 -0.0 -0.6 -0.6 -1.5 -0.6 -1.2 0.2 -0.8 0.6 0.1 0.3 0.4 -1.4 -1.0 -0.4 -1.1 -1.2 -1.0 0.4 -1.5 -1.3 -1.6 -1.8 -1.3 -0.9 -1.2 -1.7 -1.0 -0.6 -1.9
Lung FVC 1.4 6.9 20.6 -3.6 -3.7 -2.9 -3.0 -2.3 2.5 -2.5 -2.4 -2.5 -2.9 -0.6 -4.5 -2.9 -3.7 -1.1 1.7 -2.1 -3.1 -2.4 -1.7 -3.8 -1.8 -0.8 -2.8 -3.7 -2.6 -3.0 -0.4 -1.4 -1.5 -3.0 -3.5 0.2 -1.0
Neuroticism 0.5 1.1 18.4 0.1 0.8 -0.1 -0.3 0.7 -2.0 0.3 -4.3 0.3 0.1 -1.0 0.5 0.1 -0.1 -0.2 1.5 1.0 0.1 -0.0 0.5 0.6 0.2 -0.4 0.7 0.2 0.3 0.6 -1.6 -0.2 -0.1 0.5 1.7 -1.1 0.0
Chronotype (morning person) 0.3 0.6 9.0 -0.6 0.5 -0.2 -0.3 -0.4 1.0 -0.2 3.0 -0.2 -1.1 0.0 -1.4 -0.9 -1.0 -0.6 0.1 -0.6 -0.5 -0.3 -0.1 -0.9 -0.3 -0.2 -0.4 -0.5 -0.3 -0.2 -0.3 -0.2 0.2 0.2 -1.3 -0.1 0.2
Hair Pigment 0.0 0.6 1.9 -0.7 -1.1 -0.1 0.9 -0.9 -0.8 -0.5 -0.4 -0.5 -0.7 -0.7 0.1 -0.1 -0.6 -0.6 0.2 -0.8 0.7 -0.8 -0.9 -0.9 -0.8 -0.7 -0.7 -0.6 -0.4 -0.8 -0.7 -1.0 -0.2 -1.4 -1.1 -0.9 -1.3
Tanning 0.0 0.2 1.2 0.2 0.5 -0.3 1.1 0.5 0.7 -0.0 0.4 -0.0 -0.6 0.2 -0.1 0.3 0.3 -0.1 0.4 0.1 -0.6 -0.0 -0.3 -0.4 -0.4 0.0 -0.4 0.1 -0.5 -0.1 -0.5 -0.7 -0.5 -0.4 -0.2 -0.3 -0.1
Hand grip strength (left) 0.3 0.8 3.5 0.8 1.8 -0.0 1.1 0.6 1.4 0.6 1.9 0.6 1.1 0.7 1.4 1.3 1.0 0.5 -0.5 -0.2 0.4 0.5 0.4 0.7 0.5 0.6 0.7 1.2 0.5 1.3 0.7 0.3 0.2 0.8 -0.9 1.0 0.2
Number of treatments/medications taken 0.6 1.1 7.8 -0.6 -2.8 0.6 0.3 -0.5 -1.6 -0.1 0.0 -0.1 -0.6 0.3 -0.4 -1.2 -1.2 -0.2 -0.6 0.4 0.3 -0.3 2.1 0.6 2.2 -0.0 1.5 -1.6 0.3 -0.6 1.4 -0.7 0.8 -0.9 0.5 0.8 1.1
Average weekly spirits intake 0.8 0.9 2.5 -1.2 -0.8 -0.9 -0.5 -1.0 -0.8 -1.1 -0.8 -1.1 -1.6 -0.3 -0.9 -0.6 -1.1 -0.8 0.4 -0.5 -1.2 -1.2 -0.1 -1.3 0.0 -0.8 -0.5 -1.1 -1.3 -0.6 -0.9 -1.3 -1.1 -1.1 -0.9 -1.2 -1.3
Sensitivity / hurt feelings 0.4 0.7 4.6 0.8 0.5 0.1 0.7 1.1 -0.7 0.9 -2.1 0.9 0.4 0.3 0.5 0.6 0.5 0.6 0.8 1.0 0.5 0.8 -0.6 -0.3 -0.8 0.5 -0.5 1.5 0.6 0.9 -0.4 0.8 0.6 1.6 0.9 0.1 1.0
Frequency of depressed mood in last 2 weeks 1.1 1.5 4.7 -1.6 -0.6 -1.0 -1.6 -0.9 -1.4 -1.1 -1.7 -1.1 -0.7 -2.2 -1.3 -1.7 -1.8 -1.1 1.8 -0.1 -0.7 -1.5 0.7 0.3 0.5 -1.3 0.6 -1.9 -0.5 -0.4 -1.3 -0.9 -0.5 -1.3 0.7 -1.1 -2.0
Hearing difficulty/problems: Yes 0.6 0.9 6.4 1.1 1.0 0.1 2.5 0.8 0.1 0.9 -0.7 0.9 0.1 1.6 1.4 2.0 1.8 1.3 -0.6 0.2 0.2 1.1 -0.7 -0.1 -0.6 1.2 -0.3 0.7 -0.3 0.3 -0.2 0.6 -0.2 0.8 -1.0 0.5 0.5
Relative age of first facial hair 0.2 0.4 1.2 0.3 1.0 -0.4 0.5 -0.2 -0.9 0.0 -0.7 0.0 0.2 0.9 0.5 1.1 0.6 -0.0 0.6 -0.2 -0.1 0.4 -0.9 -1.1 -0.9 0.5 -0.9 1.1 -0.3 0.4 -0.2 0.2 -0.1 0.6 -0.7 0.3 1.0
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 6.9 -1.0 -0.7 -1.0 -0.7 -0.2 1.0 -0.4 -2.6 -0.3 -1.4 -1.1 -1.4 -0.7 -1.0 -0.1 1.5 -0.8 -1.0 -1.0 -0.6 -0.8 -0.9 -0.4 -1.2 -1.3 -1.1 -0.8 -1.6 -0.8 -0.9 -1.7 -1.0 -0.6 -1.2
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.6 -0.9 -1.6 -0.1 -0.4 -0.5 0.9 0.1 -0.7 0.1 -0.9 0.3 -0.8 -0.8 -1.2 -0.2 0.6 0.2 -0.6 -0.3 0.4 -0.6 0.2 0.0 0.2 -0.6 -0.5 -0.2 0.7 -0.7 0.1 -1.0 -1.2 0.4 0.7
Ever had hysterectomy (womb removed) 0.2 0.3 1.5 0.1 0.8 0.2 -0.6 0.1 0.7 0.2 -0.7 0.2 -0.3 -0.3 -1.2 -0.4 -0.0 0.5 -0.3 0.1 0.3 0.2 -0.5 -0.6 -0.7 0.4 -1.0 -0.6 0.1 -0.3 -0.5 0.6 0.5 -0.3 0.0 0.4 -0.7
Systolic blood pressure, automated reading 1.4 4.0 14.0 -2.5 -3.7 -1.3 -2.0 -2.3 0.2 -2.6 -1.6 -2.6 -2.0 -1.4 -2.3 -2.6 -2.5 -1.7 0.9 -1.4 -1.6 -2.2 0.2 -1.3 0.4 -1.8 -0.5 -3.4 -1.7 -3.5 -0.4 -2.0 -1.6 -2.8 -0.8 -1.5 -1.4
Eye problems/disorders: Diabetes related eye disease 0.1 0.2 1.7 0.0 0.8 0.2 -0.6 0.2 -0.3 0.3 -1.3 0.3 0.1 -0.4 -0.1 0.3 0.2 0.3 0.2 -0.0 0.6 -0.0 -0.1 0.1 -0.1 -0.0 0.1 0.4 0.1 0.2 -0.7 -0.2 0.3 -0.2 0.3 -0.5 -0.2
Angina 1.1 1.4 4.1 1.0 -0.7 1.4 1.3 1.0 0.6 0.6 1.3 0.5 0.8 1.4 0.8 0.2 0.8 1.1 -1.5 0.7 1.6 1.4 0.5 1.0 0.6 1.2 0.6 0.1 1.3 0.7 2.0 1.9 2.0 1.4 1.4 1.2 1.7
Medication for hormone replacement therapy 0.4 0.5 2.0 0.5 -0.6 0.6 -0.4 0.6 -0.4 1.0 0.9 1.0 0.7 0.3 -0.3 -0.0 0.4 0.6 -0.6 1.2 -0.0 0.6 0.5 0.9 0.5 0.4 0.9 0.9 0.9 0.8 0.6 0.4 0.3 0.9 0.6 0.6 1.4
Vitamin and mineral supplements 0.1 0.1 0.4 0.0 0.6 -0.2 -0.0 -0.1 0.5 -0.1 0.1 -0.1 0.4 0.1 -0.2 -0.2 0.3 0.0 0.4 -0.3 -0.1 0.2 -0.6 -0.5 -0.6 0.2 -0.5 -0.5 0.0 -0.4 0.2 0.2 -0.3 -0.2 0.4 0.1 -0.2
Supplements: Zinc 0.3 0.3 2.6 -0.3 -0.3 -0.1 -1.0 -0.4 1.2 -0.3 -1.6 -0.3 -0.4 -0.7 -0.9 -0.8 -0.5 -0.4 0.8 0.4 0.1 -0.5 -0.2 -0.2 -0.4 -0.6 -0.3 0.3 0.0 -0.1 -1.0 -0.1 0.2 -0.2 0.2 -0.9 -0.1
Medication: Co-codamol 1.1 1.3 4.6 -1.5 -2.1 -1.1 -1.6 -1.2 -1.3 -1.1 -0.7 -1.1 -1.8 -0.6 -1.4 -1.1 -1.9 -0.6 0.9 -1.2 -1.2 -1.4 0.2 -0.8 0.1 -0.3 -0.5 -1.7 -1.2 -1.0 -0.2 -0.7 -0.3 -1.4 -0.9 0.4 -1.1
Medication: Metformin 1.1 1.5 8.0 0.0 0.0 -0.8 0.8 1.0 0.7 0.1 0.1 0.1 -0.5 1.6 -1.1 1.5 0.9 1.2 1.1 -0.8 -0.3 0.7 -2.8 -2.3 -2.8 1.6 -2.8 0.6 -1.1 0.3 -0.6 1.3 -0.1 0.2 -1.9 0.4 0.7
Diabetes (father) 1.0 1.3 8.9 0.8 2.4 0.0 0.5 1.4 3.0 0.9 -0.1 0.9 -0.3 1.4 0.7 1.4 0.8 1.8 -0.7 0.1 0.1 1.0 -1.3 -0.3 -1.4 1.6 -1.6 1.1 -0.2 0.6 0.3 1.2 0.7 1.1 -0.4 1.2 0.2
Diabetes (mother) 1.9 2.4 8.6 -2.1 -0.4 -1.9 -1.0 -1.2 0.1 -1.4 -1.5 -1.3 -2.4 -0.6 -1.2 -0.4 -1.8 -1.3 1.9 -1.6 -2.9 -1.7 -0.6 -1.8 -0.5 -0.9 -1.1 -0.7 -2.4 -1.3 -1.8 -1.8 -2.2 -1.5 -2.5 -1.1 -1.2
Severe depression (siblings) 2.5 2.7 8.1 -1.8 -2.1 -1.4 -1.3 -1.9 -1.3 -1.7 -2.8 -1.7 -1.1 -2.1 -1.1 -1.7 -1.7 -1.8 2.5 -1.1 -1.5 -1.9 -0.8 -1.2 -1.0 -1.9 -0.5 -1.3 -1.2 -1.9 -1.9 -2.0 -1.6 -2.1 0.3 -2.0 -1.3
Pack years adult smoking proportion 0.6 0.9 3.5 1.4 0.6 1.3 1.4 1.2 0.8 0.8 1.7 0.8 0.5 0.7 1.0 1.1 1.7 1.2 -0.8 0.1 1.9 1.1 -0.8 0.4 -1.0 0.9 -0.6 0.8 0.4 0.5 -0.3 0.9 1.0 0.9 0.3 0.1 0.4
Impedance of leg (right) 0.3 1.6 8.0 1.1 1.2 1.4 0.8 1.5 2.8 0.9 1.2 0.9 0.3 1.8 1.4 0.9 0.8 1.3 -1.7 0.4 1.1 1.4 0.7 1.0 0.8 1.3 0.5 0.9 0.6 1.0 2.3 1.2 1.4 1.4 0.0 2.0 0.9
Leg fat-free mass (left) 0.3 1.3 10.8 -0.4 1.2 -0.8 -0.5 -1.0 -3.3 -0.7 0.4 -0.7 0.9 -2.0 -0.6 -0.5 0.0 -1.4 1.0 -0.0 -0.3 -1.0 -0.5 -0.4 -0.6 -1.5 -0.2 -0.0 0.2 -0.5 -2.4 -1.0 -0.9 -0.6 1.5 -2.4 -1.1
Trunk fat percentage 0.4 1.4 4.0 -0.5 0.3 -1.1 0.9 -0.6 -2.0 -0.9 -1.7 -0.9 -1.5 -0.3 -0.5 0.2 -0.3 -0.5 1.6 -1.7 -0.7 -0.9 -1.6 -1.9 -1.7 -0.6 -1.8 -0.7 -1.3 -1.0 -1.9 -1.2 -1.0 -1.0 -0.3 -1.6 -0.9
Hand grip strength (right) 0.2 0.5 7.5 0.0 0.9 -0.3 0.9 0.1 -0.3 -0.4 2.7 -0.4 0.4 0.5 0.7 0.5 0.3 -0.1 -1.0 -0.8 -0.1 -0.2 0.9 0.5 1.2 0.0 0.7 -0.2 -0.1 0.1 0.6 -0.6 -0.4 0.0 -0.3 0.3 -0.3
Townsend deprivation index at recruitment 3.4 4.8 11.2 2.7 0.5 2.5 2.9 3.1 0.7 2.6 0.9 2.6 0.9 2.4 3.2 2.6 2.3 2.3 -1.7 1.9 2.4 2.5 1.2 2.2 1.1 2.0 1.1 2.9 1.6 3.3 1.3 1.8 2.3 2.7 -0.5 1.6 2.4
Current tobacco smoking 0.2 0.3 1.6 0.2 -0.8 0.5 0.4 0.2 0.7 -0.2 -0.6 -0.2 -0.0 -0.6 0.2 -0.8 -0.4 -0.4 0.8 0.5 1.1 -0.3 -0.2 0.0 -0.5 -0.7 -0.0 -0.0 0.6 0.6 -0.6 0.1 0.9 0.2 1.2 -0.9 0.7
Average weekly fortified wine intake 0.2 0.3 1.6 0.3 0.0 -0.4 0.2 0.7 0.2 0.5 0.4 0.5 -0.2 1.3 -0.5 0.7 0.3 1.0 -0.5 0.2 0.2 0.4 -0.0 -0.4 0.1 1.1 -0.1 0.2 -0.1 0.2 0.7 0.3 0.2 0.3 -0.2 0.8 0.9
Maternal smoking around birth 0.3 0.4 2.9 0.3 1.7 -0.1 -0.2 0.4 -1.1 0.0 0.9 0.0 0.2 1.1 -0.0 1.0 0.7 0.5 -0.9 -0.5 -0.0 0.5 -0.3 -0.0 -0.1 0.8 -0.1 0.9 -0.3 0.2 0.1 0.6 0.0 1.2 0.3 -0.0 0.7
Fed-up feelings 0.8 1.4 7.4 -0.1 0.4 0.8 0.3 -0.3 -0.8 0.0 -1.7 0.0 0.0 -1.3 1.1 -1.3 -0.9 -0.8 0.1 1.1 0.9 -0.5 2.7 2.0 2.6 -1.3 2.5 -0.8 1.1 0.6 0.1 -1.1 0.6 -0.3 1.8 -0.9 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 2.3 3.0 7.0 -2.1 -1.2 -1.5 -1.5 -1.9 -1.4 -2.1 -2.2 -2.1 -1.6 -2.5 -1.9 -2.4 -2.6 -2.2 2.2 -0.3 -1.4 -2.3 0.5 -0.3 0.5 -2.4 0.8 -2.5 -0.8 -1.1 -1.6 -1.9 -1.0 -1.0 0.8 -2.1 -1.6
Relative age voice broke 0.6 0.9 4.0 -0.6 0.5 -1.6 0.6 -1.1 -2.0 -1.4 -1.2 -1.5 -0.0 -0.1 -0.1 0.5 -0.0 -1.2 0.9 -1.5 -1.0 -0.9 -0.3 -0.8 0.1 -0.9 -0.0 -0.4 -1.0 -0.5 -1.0 -1.2 -1.6 -0.3 -1.4 -1.0 -0.2
Taking other prescription medications 0.7 1.0 6.9 -0.7 -2.4 0.3 -0.0 -0.8 -2.6 -0.4 -0.6 -0.4 -0.8 0.1 0.5 -0.7 -1.1 -0.4 -0.1 -0.4 -0.4 -0.6 2.0 0.7 2.2 -0.3 1.6 -1.2 -0.2 -0.6 1.5 -0.7 -0.1 -0.8 -0.2 0.6 0.3
Age when periods started (menarche) 1.1 2.7 10.8 1.5 1.3 -0.2 3.3 1.8 -1.1 1.1 2.2 1.1 0.2 2.7 1.6 3.0 2.0 2.2 -1.0 -0.4 0.9 1.5 -1.7 -0.7 -1.5 2.3 -1.7 1.8 -0.2 1.2 1.3 1.5 0.5 1.4 -1.5 2.3 1.0
Bilateral oophorectomy (both ovaries removed) 1.5 1.7 8.4 -1.5 -2.2 -0.9 -1.4 -1.7 -0.7 -1.1 -2.9 -1.0 -1.3 -1.6 -1.5 -1.6 -1.9 -1.2 0.6 0.1 -0.2 -1.5 0.7 -0.4 0.6 -1.2 -0.1 -1.9 -0.7 -1.1 -1.1 -1.4 -0.5 -1.6 -0.4 -1.0 -1.8
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 7.6 0.9 0.4 0.9 1.2 0.7 -0.3 0.9 0.9 0.9 2.5 -0.9 1.1 0.4 1.0 0.0 -0.8 1.1 1.5 0.6 1.1 2.1 1.2 -0.3 1.8 1.0 1.9 1.1 0.1 0.1 0.6 1.0 2.8 -0.4 0.7
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 2.1 0.7 0.3 1.2 -0.5 -0.5 -0.3 0.4 0.5 0.4 0.7 -1.5 -0.3 -0.8 0.2 0.0 -1.1 1.1 0.7 0.2 -0.2 0.7 -0.5 -0.6 0.1 -0.1 1.1 -0.1 -0.1 0.8 0.3 0.4 1.4 -0.1 -0.9
Qualifications: CSEs or equivalent 1.3 1.7 4.3 1.3 1.4 1.6 2.0 1.1 0.2 1.0 1.1 1.0 1.3 0.5 1.1 0.4 0.7 1.0 -1.7 1.0 2.1 1.0 1.5 2.1 1.4 0.6 1.4 0.8 1.7 1.3 1.6 0.8 1.8 1.2 1.2 1.3 0.7
Serious illness, injury or assault to yourself 1.6 1.9 12.1 -1.2 -1.2 -1.2 1.2 -0.6 -0.5 -1.1 0.1 -1.1 -2.5 0.6 -1.0 0.1 -0.9 0.1 -0.4 -1.8 -1.2 -1.0 -0.7 -2.1 -0.4 -0.0 -1.7 -1.7 -2.2 -2.0 -0.5 -1.2 -1.6 -2.1 -3.5 -0.5 -1.5
High blood pressure 0.3 0.9 10.7 -0.8 -3.3 -0.4 0.1 -1.1 -0.3 -0.9 -1.0 -0.9 -0.6 -0.3 -1.4 -1.1 -0.8 -0.4 -0.1 -0.2 0.6 -0.7 0.1 -0.7 0.3 -0.3 -0.4 -2.0 -0.4 -1.5 0.2 -0.3 -0.1 -1.2 -0.5 -0.0 -0.6
Hayfever, allergic rhinitis or eczema 0.2 0.5 2.6 -0.5 1.6 -0.7 -0.6 -0.3 -0.5 -0.1 -0.8 -0.1 -0.4 -0.0 -0.1 0.0 -0.0 -0.0 0.2 0.3 -1.3 0.2 -1.3 -1.1 -1.3 0.1 -1.0 -0.8 -0.6 -0.9 -0.3 -0.0 -0.8 -0.5 -0.1 -0.5 -0.9
Multivitamins +/- minerals 0.6 0.7 3.2 -1.0 -1.0 -0.8 -0.6 -0.5 -1.1 -0.5 -1.6 -0.5 -1.2 -0.8 -1.0 -0.5 -0.9 -0.6 1.5 -0.3 -0.6 -0.9 -0.5 -0.5 -0.6 -0.8 -0.3 -0.1 -0.8 -0.4 -1.8 -1.0 -0.5 -0.4 -0.8 -1.3 -0.3
Stomach or abdominal pain in last month 1.7 2.1 5.3 -1.7 -1.7 -1.9 0.5 -1.8 -0.5 -2.3 -0.5 -2.3 -1.8 -0.6 -0.9 -0.3 -1.4 -1.3 0.6 -2.3 -1.2 -2.0 -0.5 -0.8 -0.0 -1.4 -0.5 -1.1 -1.9 -1.7 -0.9 -2.1 -1.8 -1.2 -1.7 -1.5 -1.7
Supplements: Glucosamine 0.2 0.2 1.8 -0.3 -1.0 0.4 -0.2 -0.0 -0.4 0.2 -0.4 0.2 -0.1 -0.8 -0.5 -0.5 -0.5 0.1 0.4 0.1 -0.1 -0.3 -0.3 -0.4 -0.5 -0.2 -0.2 -0.3 -0.1 -0.4 -0.1 -0.3 -0.2 -1.3 -0.7 0.6 0.3
Diverticular disease/diverticulitis (self-reported) 2.0 2.3 8.8 -1.8 -3.0 -1.5 -1.4 -2.2 0.4 -1.9 -2.2 -1.9 -0.6 -1.5 -1.0 -1.4 -1.5 -1.8 1.4 -0.9 -1.7 -1.9 -0.6 -1.2 -0.4 -1.9 -0.1 -1.5 -0.9 -2.4 -0.6 -1.6 -1.7 -1.6 -0.1 -1.7 -0.5
Medication: Atenolol 0.2 0.2 1.5 0.4 0.1 0.3 0.8 0.8 1.2 0.6 0.3 0.6 -0.4 0.2 -0.4 0.6 0.5 0.9 -0.3 0.2 -0.1 0.4 -0.2 -0.2 -0.2 0.6 -0.5 0.0 -0.2 -0.0 -0.5 0.4 -0.0 0.4 -0.1 0.4 -0.2
Medication: Levothyroxine sodium 0.9 1.5 4.5 1.7 0.8 0.6 1.8 1.4 0.0 1.2 0.2 1.2 1.4 1.6 1.6 2.1 2.0 1.2 -0.5 0.6 1.7 1.4 0.1 0.9 0.2 1.5 0.3 1.6 0.9 1.5 0.4 1.1 1.1 1.2 0.5 0.5 1.9
Sitting height 0.3 2.2 9.8 0.7 2.4 1.0 -0.3 -0.2 -1.9 0.6 1.6 0.6 3.1 -1.7 1.7 -0.0 1.1 -1.1 -1.1 2.3 1.2 0.3 1.4 1.7 1.5 -1.3 2.0 2.0 2.2 0.9 -0.5 -0.2 0.4 0.9 2.9 -1.4 -0.0
Chronic bronchitis/emphysema (father) 0.5 0.6 2.1 -0.7 -1.4 -0.2 -0.6 -1.2 -0.6 -1.3 0.9 -1.3 -0.8 -0.4 -0.4 -0.9 -0.9 -1.0 -0.5 -1.4 -0.5 -0.9 -0.4 -1.0 -0.2 -1.1 -0.3 -0.2 -0.4 -0.6 0.1 -0.4 -0.5 0.2 -0.5 -1.1 -0.0
High blood pressure (mother) 0.7 0.9 3.2 -0.9 -0.9 -1.2 -0.4 -1.1 -0.9 -1.1 -1.3 -1.1 0.4 -1.8 -0.9 -0.9 -0.7 -1.1 1.4 -0.8 -0.2 -1.5 0.1 -0.2 0.1 -1.4 0.3 -0.7 -0.1 -0.6 -1.3 -1.3 -0.9 -0.8 -0.2 -1.3 -0.8
Body mass index (BMI) 0.7 3.0 7.8 -1.7 -0.8 -1.6 -1.1 -1.8 -2.0 -1.6 -1.8 -1.6 -1.9 -1.6 -2.0 -1.4 -1.6 -1.5 2.5 -1.5 -1.4 -1.9 -1.3 -2.2 -1.4 -1.6 -1.5 -1.7 -1.5 -1.8 -2.7 -1.9 -1.5 -1.9 0.3 -2.8 -1.5
Impedance of leg (left) 0.2 0.8 5.2 0.5 1.0 0.8 0.5 1.3 2.3 0.5 1.0 0.5 -0.4 1.6 0.8 0.6 0.4 1.0 -1.4 0.1 0.8 1.0 0.2 0.4 0.3 1.1 -0.1 0.4 -0.0 0.5 1.5 0.9 0.9 0.9 -0.4 1.5 0.4
Leg predicted mass (left) 0.3 1.3 10.5 -0.4 1.3 -0.8 -0.5 -1.0 -3.2 -0.7 0.4 -0.7 0.9 -2.1 -0.6 -0.5 0.0 -1.4 1.1 -0.0 -0.3 -1.0 -0.6 -0.4 -0.6 -1.5 -0.2 0.0 0.2 -0.5 -2.4 -1.0 -0.9 -0.6 1.5 -2.4 -1.1
Trunk fat mass 0.4 1.9 7.8 -0.9 0.4 -1.3 0.2 -1.2 -2.8 -1.3 -1.2 -1.3 -1.1 -1.2 -0.8 -0.5 -0.6 -1.3 1.8 -1.4 -0.9 -1.4 -1.4 -1.9 -1.4 -1.3 -1.4 -0.9 -1.1 -1.2 -2.4 -1.6 -1.3 -1.2 0.4 -2.4 -1.3
Waist circumference 1.0 3.6 11.4 -1.9 -2.2 -1.4 -1.1 -2.2 -2.1 -2.0 -1.8 -2.0 -1.6 -2.1 -1.9 -2.1 -1.7 -2.2 2.4 -1.1 -1.2 -2.1 -0.7 -2.0 -0.8 -2.2 -1.0 -1.9 -1.3 -2.2 -2.8 -2.3 -1.7 -2.0 0.8 -3.4 -1.5
Number of incorrect matches in round 0.5 0.8 6.1 -0.5 -0.0 0.4 -1.7 -0.8 2.1 -0.4 -2.5 -0.4 -0.2 -1.2 -0.2 -1.4 -0.8 -0.9 1.2 0.1 -0.2 -0.7 0.6 -0.1 0.3 -0.9 0.9 0.1 0.2 0.2 -0.5 -0.3 -0.0 0.3 1.0 -0.5 0.1
Past tobacco smoking 0.4 0.8 4.0 0.4 -0.8 1.0 -0.2 -0.6 -0.4 -0.0 -0.2 -0.1 1.5 -0.8 0.0 -1.2 -0.1 -0.6 -0.3 0.9 0.9 0.4 1.6 1.3 1.4 -0.6 1.6 -0.2 1.4 0.2 1.0 0.4 0.8 0.6 2.0 0.4 -0.1
Alcohol usually taken with meals 1.2 2.0 6.0 1.4 1.0 1.9 0.4 1.0 2.5 1.4 1.0 1.3 1.5 1.4 1.6 0.6 1.2 0.9 -2.1 1.1 1.4 1.9 0.5 1.1 0.6 1.0 0.8 1.2 1.6 1.0 2.4 1.6 1.5 1.6 0.7 1.5 1.9
Nervous feelings 0.6 1.2 6.1 0.5 -0.3 0.3 0.5 -0.1 -0.6 0.2 -2.3 0.2 1.2 -1.3 1.6 -0.1 0.5 -1.0 0.4 1.5 0.9 -0.1 1.1 1.3 1.1 -1.2 1.7 0.8 1.2 0.6 -1.0 -0.7 0.0 0.6 2.5 -2.1 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.3 6.2 -0.9 -0.1 -0.7 -0.9 -1.0 -1.0 -0.9 -2.2 -0.9 0.1 -2.5 -0.9 -1.4 -1.2 -1.3 1.6 0.6 0.2 -1.4 0.7 0.4 0.5 -1.5 0.7 -1.2 0.1 -0.3 -1.7 -1.1 -0.3 -1.2 1.2 -1.4 -1.8
Hearing difficulty/problems with background noise 0.5 0.7 3.2 0.6 1.1 -0.6 1.8 0.0 -1.1 0.3 -1.4 0.3 0.7 -0.3 1.4 1.4 1.1 -0.2 0.8 0.5 0.5 -0.1 -0.2 0.1 -0.0 -0.4 0.6 1.8 0.1 0.5 -1.4 -0.7 -0.7 0.7 0.2 -1.2 0.2
Hair/balding pattern: Pattern 2 0.9 1.1 2.9 0.9 0.8 0.1 0.1 1.7 -1.4 1.3 0.4 1.3 0.9 1.6 -0.2 1.6 1.1 1.7 -0.8 0.8 0.6 1.2 -0.2 0.1 -0.1 1.6 -0.2 1.4 0.6 1.6 0.7 1.3 1.2 1.3 0.3 1.4 0.9
Had menopause 0.8 1.0 3.0 1.0 0.4 1.6 0.5 1.5 1.6 1.2 0.3 1.2 0.5 1.1 1.1 0.5 0.9 1.0 -0.9 1.4 1.6 1.2 0.6 0.5 0.4 0.9 0.6 0.7 0.8 0.8 0.7 0.9 1.4 0.2 -0.2 0.6 1.7
Had other major operations 0.4 0.5 2.5 -0.2 0.3 -0.4 0.5 -0.2 -1.4 0.0 -0.8 0.0 0.0 -0.3 0.5 0.5 0.3 -0.8 0.9 0.5 0.1 -0.1 0.9 0.2 1.1 -0.3 0.8 -0.1 -0.5 0.4 -1.6 -0.8 -1.1 -0.4 -0.9 -1.0 -0.1
Forced vital capacity (FVC) 0.3 1.0 6.5 -0.9 -0.3 0.2 -2.5 -1.3 0.1 -0.4 1.1 -0.4 0.5 -1.5 -1.2 -2.3 -1.4 -1.0 -1.0 1.2 -0.4 -0.5 0.8 -0.0 0.6 -1.0 0.3 -1.2 0.8 -0.9 0.9 -0.2 0.3 -0.8 0.6 0.2 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 8.4 0.5 0.7 0.8 0.4 0.1 -0.5 0.4 1.2 0.4 2.2 -1.4 0.1 -0.1 0.8 -0.5 -0.4 0.8 1.1 0.5 0.6 1.5 0.7 -0.7 1.3 0.9 1.6 0.5 -0.6 0.1 0.2 1.3 2.9 -1.1 0.1
Ever unenthusiastic/disinterested for a whole week 1.8 2.2 8.2 -2.0 -2.9 -1.3 -1.4 -0.7 -0.6 -1.2 -1.8 -1.1 -2.6 -0.2 -1.4 -1.3 -2.4 -0.2 0.9 -0.7 -1.8 -1.2 -0.1 -1.5 -0.2 -0.3 -1.0 -2.2 -2.0 -1.4 -0.3 -1.3 -0.9 -2.5 -2.0 0.0 -1.9
Qualifications: None of the above 0.6 1.3 8.1 -0.8 -1.8 0.5 -1.4 -1.4 -0.3 -0.9 0.4 -1.0 -0.6 -1.8 -0.8 -1.7 -0.8 -1.6 0.0 -0.1 0.4 -1.1 0.8 0.3 0.8 -1.9 1.2 -0.6 0.1 -0.7 -1.3 -1.0 -0.5 -0.2 1.1 -2.8 -1.1
Financial difficulties in last 2 years 0.2 0.3 0.8 -0.5 -0.6 -0.1 0.3 -0.3 -0.5 -0.2 -0.7 -0.2 -0.5 -0.6 -0.0 -0.2 -0.3 -0.4 0.3 0.3 -0.9 -0.5 -0.5 -0.6 -0.5 -0.6 -0.1 -0.1 -0.5 -0.3 -0.9 -0.6 -0.7 -0.4 -0.7 -0.8 -0.5
Mouth/teeth dental problems 0.7 1.1 4.0 1.2 0.7 1.7 0.9 0.8 0.2 1.1 0.8 1.1 1.2 0.3 1.6 0.4 0.8 0.6 -1.2 1.2 1.4 1.2 1.5 2.0 1.4 0.4 1.4 0.4 1.2 0.6 1.6 0.6 0.7 0.4 0.3 1.4 0.4
Heart attack 1.2 1.6 4.4 1.7 -0.6 1.8 1.8 1.4 0.0 1.7 0.1 1.7 1.3 0.6 1.3 0.7 1.4 1.2 -0.7 1.6 2.1 1.6 0.3 1.2 0.1 1.0 0.6 0.8 1.7 1.9 0.6 1.4 1.6 0.8 0.8 0.8 1.1
Allergy 0.7 1.6 4.8 1.4 -0.7 1.7 0.8 1.3 0.9 1.2 1.8 1.2 1.0 0.9 1.1 0.7 1.0 1.1 -1.5 0.8 2.2 1.2 1.1 1.8 1.1 1.0 0.9 1.4 1.2 1.6 1.2 1.3 1.5 1.3 -0.1 1.6 0.9
Pain all over the body in last month 0.2 0.2 1.6 -0.1 0.6 -0.6 0.5 -0.1 -1.0 -0.3 -0.6 -0.3 0.5 -0.2 -0.0 0.3 0.4 -0.5 0.2 -0.2 -0.5 -0.2 -0.6 -0.6 -0.4 -0.4 -0.3 0.5 -0.1 -0.3 -0.5 -0.3 -0.9 -0.1 -0.5 -1.3 -0.3
Diabetes (self-reported) 0.8 1.3 7.5 -0.2 -0.3 -0.6 0.1 0.3 -0.5 -0.2 -0.4 -0.2 -1.1 1.1 -1.3 1.1 0.6 0.9 1.0 -1.0 -0.0 0.3 -2.7 -2.0 -2.7 1.0 -2.6 -0.1 -1.4 -0.6 -0.9 0.5 -0.2 -0.5 -1.9 0.0 0.0
Hayfever/allergic rhinitis (self-reported) 1.5 1.9 6.3 -1.0 1.1 -2.1 -1.0 -0.1 -1.7 -1.1 0.8 -1.1 -1.3 0.5 -1.6 0.7 -0.0 0.0 0.5 -1.9 -1.3 -0.5 -2.5 -2.4 -2.2 0.4 -2.5 -0.2 -2.0 -1.2 -1.7 0.1 -1.7 -0.2 -2.3 -1.0 -0.9
Medication: Ramipril 0.2 0.3 1.2 0.2 -0.7 1.1 0.7 -0.1 0.7 0.4 0.2 0.3 -0.6 0.6 0.0 -0.1 0.1 0.9 -1.1 0.2 0.9 0.6 -0.2 -0.3 -0.2 0.6 -0.7 -0.3 0.1 -0.3 0.6 0.7 0.9 0.3 -0.4 0.6 -0.5
Medication: Simvastatin 0.3 0.5 2.4 -0.5 -1.6 -0.6 0.4 -0.9 1.0 -1.0 -0.5 -1.1 0.1 0.1 -0.8 -1.1 -0.8 -0.8 0.5 -0.5 0.2 -0.7 0.1 -0.6 0.2 -0.6 0.3 -1.1 0.3 -0.3 1.0 -0.2 0.2 -0.2 -0.3 0.0 1.3
Fluid intelligence score 0.6 1.2 8.3 0.6 0.3 0.6 1.5 1.3 0.3 1.2 0.9 1.2 0.0 1.9 0.6 0.8 0.4 1.8 -1.3 0.6 -0.4 1.2 -0.3 -0.1 -0.3 1.8 -0.6 -0.3 0.1 0.2 2.2 1.0 0.8 0.5 -0.3 2.9 1.6
Illnesses of siblings 0.2 0.3 4.2 0.3 2.1 -0.1 0.8 0.6 0.2 0.2 0.9 0.2 0.2 0.2 0.7 0.6 0.5 0.1 -0.1 0.4 -0.7 0.3 0.0 0.3 0.1 0.1 0.3 0.6 0.0 0.3 -0.0 0.1 -0.3 0.6 -0.0 -0.2 0.1
Neuroticism score 0.6 1.2 21.5 0.2 0.7 -0.5 -0.0 0.9 -2.3 0.4 -4.6 0.4 0.0 -0.6 0.1 0.3 0.2 0.3 1.4 0.8 0.5 0.2 -0.5 0.2 -0.7 0.0 -0.1 0.2 0.1 0.5 -1.6 0.1 -0.1 0.5 1.6 -1.1 -0.3
Weight 0.4 2.2 10.0 -1.1 0.5 -0.9 -0.6 -1.7 -3.1 -1.3 -0.2 -1.4 -0.3 -2.2 -0.9 -1.3 -0.8 -2.0 1.6 -0.5 -0.7 -1.6 -0.5 -1.2 -0.6 -2.1 -0.4 -0.8 -0.4 -1.2 -2.6 -1.9 -1.3 -1.3 1.5 -3.2 -1.4
Impedance of arm (right) 0.7 3.4 9.5 2.5 2.4 1.0 2.5 2.2 1.4 1.6 0.2 1.6 1.8 2.5 2.3 3.1 2.7 2.1 -1.5 -0.0 1.3 2.3 -0.4 1.3 -0.3 2.3 0.0 2.0 0.8 1.9 1.6 2.2 1.3 1.9 -1.1 2.6 1.4
Arm fat percentage (right) 0.3 1.3 5.0 -0.6 -0.1 -1.0 0.0 -1.1 -2.2 -0.9 -1.6 -0.9 -1.2 -0.6 -0.8 -0.2 -0.4 -0.6 1.8 -1.4 -0.7 -0.9 -1.3 -1.6 -1.4 -0.6 -1.4 -0.9 -1.1 -1.1 -1.8 -1.0 -0.9 -1.1 -0.0 -1.6 -1.0
Trunk fat-free mass 0.5 3.1 11.7 -1.4 0.1 -0.7 -1.6 -2.4 -3.3 -1.6 1.5 -1.6 0.8 -3.4 -0.9 -2.1 -1.0 -2.9 0.9 0.7 -0.8 -1.9 0.7 -0.2 0.7 -3.1 1.0 -0.7 0.4 -1.4 -2.3 -2.2 -1.5 -1.2 2.1 -3.4 -1.6
Hip circumference 0.4 1.6 6.6 -0.9 -0.2 -0.3 -1.0 -1.7 -2.0 -1.0 -0.8 -1.0 -0.5 -2.2 -0.7 -1.8 -1.2 -1.8 1.4 0.4 -0.2 -1.4 -0.0 -0.7 -0.2 -2.0 0.0 -1.0 0.1 -1.0 -1.9 -1.6 -0.5 -1.3 1.6 -2.6 -1.1
Time employed in main current job 0.6 0.7 2.5 -0.1 0.1 -1.3 0.1 0.5 -0.7 -0.2 -1.2 -0.2 -0.7 0.8 -0.6 0.9 0.3 0.7 0.3 -0.9 -1.3 0.0 -1.4 -1.3 -1.3 0.9 -1.6 -0.2 -1.1 -0.2 -0.7 0.3 -0.5 -0.1 -1.4 0.3 -0.8
Alcohol intake versus 10 years previously 0.4 0.6 3.0 0.5 0.2 0.4 1.7 0.8 0.7 0.7 0.5 0.7 -0.8 1.4 0.3 0.5 0.1 1.1 -0.3 -0.0 0.7 0.6 0.1 -0.3 -0.1 1.2 -0.7 0.3 -0.1 0.9 0.7 0.5 1.0 0.6 -0.8 1.6 0.3
Father’s age at death 0.6 0.8 3.9 -0.7 -1.8 -1.0 -0.6 -1.1 -2.0 -0.9 -0.2 -0.9 -0.2 -0.9 -0.3 -0.8 -0.8 -1.2 1.8 -0.1 -1.1 -0.8 0.0 -0.7 -0.0 -1.0 -0.3 -0.2 -0.5 -1.0 -1.1 -1.0 -1.1 -0.6 -0.1 -1.2 -0.1
Worrier / anxious feelings 0.5 0.9 6.0 0.8 2.2 0.3 0.4 1.2 1.1 1.1 -2.5 1.2 0.1 0.6 0.7 0.9 0.7 1.2 -0.4 1.1 0.5 1.1 -0.1 0.6 -0.3 1.2 -0.3 0.3 0.2 0.7 -0.1 0.8 0.6 0.7 1.1 0.8 -0.3
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.1 -0.8 -0.2 -0.7 -0.2 -0.1 -0.0 -0.4 -1.4 -0.3 -0.7 -1.2 -0.7 -0.6 -1.1 -0.4 1.0 0.2 -0.6 -0.8 0.5 0.1 0.4 -0.6 0.2 -1.0 -0.2 0.2 -0.9 -0.8 -0.1 -0.6 0.1 -0.5 -1.4
Falls in the last year 0.9 1.3 10.3 -0.6 -1.0 -0.5 1.6 -1.1 -3.2 -0.8 0.2 -0.8 -1.2 -0.7 0.7 -0.2 -0.9 -1.3 0.6 -0.5 -1.1 -1.2 1.3 0.1 1.4 -1.3 1.0 -0.4 -0.8 -0.2 -0.4 -2.2 -1.2 -1.4 -1.1 -0.9 -0.7
Hair/balding pattern: Pattern 3 0.9 1.3 3.9 -1.2 -2.0 -0.8 -0.3 -1.0 0.1 -1.2 -1.5 -1.2 -1.6 -0.5 -0.8 -0.9 -1.4 -0.6 0.8 -1.7 -1.5 -1.1 -0.3 -1.0 -0.4 -0.5 -1.0 -1.7 -1.5 -1.6 -0.3 -1.1 -1.1 -1.7 -1.3 -0.1 -0.9
Number of live births 1.5 2.1 5.3 -1.5 -1.2 -2.1 -0.5 -1.3 -1.3 -1.7 -1.0 -1.7 -1.2 -0.5 -2.1 -0.8 -1.0 -1.2 1.1 -2.0 -2.3 -1.3 -1.2 -1.9 -1.0 -0.9 -1.5 -1.3 -1.6 -1.7 -1.5 -1.2 -1.9 -1.1 -0.9 -2.0 -0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 7.2 -0.8 -0.5 -0.0 -2.7 -0.9 -0.2 -0.3 0.1 -0.3 0.3 -1.3 -1.3 -1.9 -1.2 -0.6 -0.7 0.9 -0.6 -0.5 0.5 -0.1 0.3 -0.6 -0.1 -1.6 0.4 -1.2 0.6 -0.3 0.0 -1.3 0.4 0.3 -1.1
Pulse rate 0.3 0.4 1.8 -0.8 -0.3 -0.9 -0.7 0.0 0.6 -0.7 -1.3 -0.7 -0.5 0.5 -1.0 0.3 -0.6 -0.1 0.7 -0.6 -0.5 -0.5 -0.8 -1.0 -0.8 0.3 -1.0 0.0 -1.0 0.1 -0.2 -0.3 -0.2 -0.5 -0.9 0.3 0.4
Happiness 4.2 5.0 10.6 -2.6 -2.0 -3.0 -1.2 -2.6 -2.0 -2.9 -3.0 -2.9 -3.2 -1.3 -1.8 -1.6 -2.9 -1.9 2.2 -2.0 -2.9 -2.8 -0.5 -1.9 -0.4 -1.8 -1.1 -2.2 -2.7 -2.3 -1.8 -2.4 -2.3 -2.2 -2.1 -1.8 -2.6
Noisy workplace 1.8 2.2 6.9 1.5 0.8 0.3 2.0 2.0 -0.1 1.3 2.5 1.3 -0.5 2.2 0.2 2.6 2.0 2.2 -1.4 -0.4 1.1 1.5 -2.0 -0.8 -1.7 2.0 -1.6 1.8 -0.3 1.3 0.1 1.6 0.7 2.1 -1.2 1.0 0.3
Qualifications: A levels/AS levels or equivalent 0.6 1.3 3.1 -0.9 0.2 -1.7 -0.4 -0.8 -1.4 -0.9 -0.3 -0.9 -0.7 0.1 -1.0 0.3 -0.3 -0.3 1.0 -1.6 -1.6 -0.4 -1.7 -1.5 -1.5 0.1 -1.6 -1.6 -1.5 -1.6 -0.3 -0.3 -1.5 -1.4 -1.8 0.3 -0.8
Serious illness, injury or assault of a close relative in last 2 years 2.0 2.3 5.6 -2.0 -1.0 -1.0 -2.4 -1.6 1.6 -1.7 -0.5 -1.7 -1.6 -1.2 -1.0 -1.8 -1.9 -1.7 1.1 -0.7 -2.3 -1.7 -0.3 -1.6 -0.3 -1.6 -0.4 -1.5 -1.5 -2.1 -0.9 -1.7 -1.9 -1.7 -0.7 -1.5 -1.6
Mouth/teeth dental problems: Dentures 0.9 1.5 5.9 -1.3 -0.9 -1.1 -0.6 -1.0 -2.4 -1.3 0.2 -1.3 -1.8 -0.8 -1.2 -0.6 -1.1 -1.3 1.2 -1.4 -0.8 -1.4 -0.4 -1.3 -0.2 -1.1 -0.3 -0.5 -1.4 -1.0 -2.3 -1.6 -1.3 -0.5 0.3 -2.4 -0.5
Asthma 1.1 2.2 5.9 -1.6 -1.0 -1.5 -1.8 -2.2 -2.4 -2.0 0.2 -2.0 -0.9 -1.5 -1.8 -1.3 -1.6 -1.7 1.4 -1.6 -1.1 -1.9 -0.1 -1.0 0.0 -1.5 -0.5 -1.9 -1.1 -1.9 -1.1 -1.4 -1.3 -1.7 0.3 -1.4 -1.2
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.8 0.1 -0.6 0.6 -0.4 0.5 0.2 0.9 1.1 0.9 0.0 0.1 -0.5 -0.5 -0.1 0.6 -1.4 0.8 -0.2 0.5 0.8 0.9 0.9 0.2 0.9 -0.2 0.6 -0.2 0.6 -0.0 0.4 0.4 1.2 0.1 0.4
Medication: Cholesterol lowering 0.5 0.7 2.8 0.2 -1.5 0.8 0.5 0.6 0.7 0.1 1.4 0.1 0.1 1.7 0.0 0.4 0.5 0.7 -1.3 -0.1 0.5 1.0 -0.4 -0.6 -0.2 1.1 -0.4 -0.1 0.1 0.2 1.6 1.2 0.9 0.9 -0.1 1.3 1.5
Depression (self-reported) 1.8 2.2 8.8 -1.8 -0.2 -2.1 -0.5 -0.7 -0.9 -1.4 -3.0 -1.4 -1.8 -1.0 -2.2 -1.4 -1.9 -0.7 2.4 -0.8 -1.2 -1.7 -1.5 -1.9 -1.6 -0.9 -1.5 -1.4 -1.3 -1.1 -1.9 -1.2 -0.9 -1.0 0.2 -1.5 -0.4
Medication: Lansoprazole 0.9 1.1 8.5 0.5 -0.5 0.9 2.1 0.9 -2.9 0.9 1.6 0.9 0.4 0.9 1.5 0.9 0.8 0.5 -0.5 -0.4 0.8 0.6 1.6 1.1 1.8 0.6 1.4 0.2 0.3 0.8 0.8 -0.3 0.5 -0.4 -0.4 0.3 0.2
Prospective memory result 0.4 0.5 3.1 -0.5 0.2 -0.5 -1.8 0.2 0.7 -0.5 0.4 -0.5 -0.3 -0.7 -0.8 -0.2 -0.1 -0.3 0.6 -0.9 -0.2 -0.4 -0.3 -0.0 -0.4 -0.1 -0.5 -0.4 -0.7 -0.3 -1.7 -0.2 -0.5 -0.7 -0.6 -1.0 -1.6
Lung cancer (father) 0.5 0.6 2.3 0.3 -0.8 1.1 0.1 0.5 -1.3 -0.2 1.5 -0.2 0.6 -0.1 0.2 -0.9 -0.3 -0.2 -0.4 0.7 0.8 0.0 1.5 0.9 1.4 -0.4 1.3 -0.2 0.9 -0.1 0.8 0.2 0.9 -0.2 1.1 -0.3 1.4
Illnesses of mother 0.5 0.6 3.2 0.4 -0.2 1.1 -1.4 -0.6 -0.7 0.3 1.8 0.3 0.5 -0.0 -0.0 -0.6 0.0 -0.1 -1.1 1.0 0.4 0.6 1.2 0.8 1.1 0.3 0.5 -0.6 0.7 -0.2 1.1 0.7 0.9 -0.5 1.8 0.6 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 3.5 -0.8 -0.9 -0.1 -1.9 -0.8 0.0 -0.3 0.1 -0.3 -0.0 -1.0 -1.1 -1.4 -1.1 -0.4 -0.5 0.4 -0.6 -0.5 0.3 -0.3 0.1 -0.5 -0.3 -1.6 0.1 -1.2 0.7 -0.3 0.0 -1.5 -0.2 0.7 -1.1
Pulse wave Arterial Stiffness index 1.6 1.9 5.9 -1.7 -0.3 -1.6 -0.9 -1.0 -1.3 -1.2 -1.4 -1.2 -2.4 -0.1 -1.3 -0.4 -1.3 -0.5 1.0 -1.2 -1.6 -1.3 -1.3 -1.8 -1.2 -0.2 -1.7 -1.6 -2.3 -1.4 -1.5 -1.3 -1.6 -1.4 -1.9 -1.0 -1.3
Impedance of arm (left) 0.6 2.9 7.8 2.2 2.1 0.8 2.8 2.1 1.5 1.5 -0.2 1.5 1.1 2.5 2.3 2.8 2.3 2.1 -1.3 -0.2 1.3 2.0 -0.3 1.1 -0.2 2.3 -0.1 1.6 0.6 1.7 1.6 1.8 1.3 1.6 -1.0 2.6 1.3
Arm fat mass (right) 0.5 2.1 7.2 -1.1 0.1 -1.3 -0.5 -1.5 -2.5 -1.3 -1.4 -1.3 -1.2 -1.5 -1.3 -0.8 -0.8 -1.3 2.1 -1.2 -0.9 -1.4 -1.3 -1.9 -1.4 -1.4 -1.4 -1.1 -1.1 -1.4 -2.7 -1.6 -1.3 -1.5 0.6 -2.6 -1.5
Trunk predicted mass 0.6 3.2 11.4 -1.4 0.1 -0.7 -1.6 -2.4 -3.2 -1.6 1.6 -1.6 0.7 -3.4 -1.0 -2.1 -1.1 -2.9 0.9 0.5 -0.8 -1.9 0.7 -0.2 0.7 -3.0 0.9 -0.7 0.3 -1.4 -2.3 -2.2 -1.5 -1.2 2.1 -3.4 -1.7
Standing height 0.3 3.3 12.4 1.5 3.2 1.5 1.1 0.1 -2.7 0.7 3.5 0.6 3.4 -1.5 2.4 0.3 1.7 -1.2 -1.9 2.2 1.6 0.6 1.7 2.2 1.8 -1.3 2.4 2.1 2.5 1.1 -0.0 -0.1 0.5 1.4 2.9 -1.0 0.2
Length of working week for main job 0.7 0.8 3.4 0.9 1.4 0.8 1.6 1.0 -1.9 1.0 1.2 1.1 0.0 0.8 1.0 0.9 0.5 0.6 -0.7 0.6 0.3 0.9 0.8 0.5 0.8 0.8 0.4 0.6 0.5 1.5 0.2 0.1 1.0 0.8 0.5 1.1 0.9
Exposure to tobacco smoke at home 1.4 1.5 7.3 -0.6 -2.4 -0.4 -0.1 -1.6 -0.8 -1.8 -0.3 -1.9 0.4 -1.8 -0.7 -2.1 -0.7 -2.4 0.2 0.3 -0.0 -1.1 0.3 -0.6 0.4 -2.4 0.6 -1.0 0.5 -1.4 -0.8 -0.8 -0.8 -0.0 0.6 -2.7 -0.4
Breastfed as a baby 1.8 2.2 4.2 1.6 0.5 1.8 0.5 1.3 0.9 1.7 0.8 1.7 1.0 1.7 1.7 1.1 1.2 1.6 -1.6 1.5 1.6 1.7 0.9 1.7 0.9 1.5 1.2 1.7 1.3 1.8 2.0 2.0 1.9 1.5 -0.3 2.0 1.9
Tense / ‘highly strung’ 0.1 0.2 1.3 0.6 0.2 0.0 -0.8 0.5 -1.1 0.2 -0.8 0.2 0.3 0.0 0.5 0.3 0.7 0.0 -0.2 0.5 0.6 0.4 -0.0 0.2 -0.0 0.1 0.1 0.8 0.3 -0.1 -0.6 0.5 -0.0 0.8 0.6 -0.9 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 2.7 4.1 13.5 -2.4 -1.1 -2.6 -1.5 -0.9 -3.7 -1.7 -3.5 -1.6 -2.6 -1.3 -2.0 -1.1 -2.3 -1.0 2.9 -1.4 -1.4 -2.1 -1.0 -2.2 -1.2 -0.9 -1.6 -2.3 -2.5 -1.8 -2.9 -2.0 -2.0 -2.8 -1.3 -1.6 -1.7
Hair/balding pattern: Pattern 4 0.1 0.4 3.1 0.1 0.8 -0.4 0.2 0.2 1.8 -0.0 -1.6 -0.1 -0.3 0.6 -0.2 0.7 0.5 -0.0 0.4 -0.1 -1.0 0.2 -0.8 -0.5 -0.7 0.2 -0.3 0.7 -0.6 -0.0 -0.4 -0.2 -0.6 0.5 -0.2 -0.4 0.1
Birth weight of first child 1.0 1.8 5.1 1.4 2.1 0.8 0.0 2.2 -0.2 1.6 0.6 1.6 1.1 1.2 -0.1 1.0 1.1 1.8 -0.9 1.3 0.8 1.6 -0.4 0.4 -0.6 1.9 -0.5 1.2 1.1 2.0 0.8 2.3 1.6 1.6 0.8 1.9 1.5
Peak expiratory flow (PEF) 0.2 0.4 1.6 -0.4 0.2 0.1 -1.2 -0.6 -0.3 0.1 -1.3 0.1 0.7 -1.1 -1.1 -1.2 -0.6 -0.3 0.1 0.6 -0.0 -0.2 -0.1 -0.3 -0.3 -0.4 -0.5 -1.0 0.7 -0.6 0.2 -0.1 0.3 -0.8 0.8 0.4 -0.3
Pulse wave reflection index 0.3 0.3 1.5 -0.6 0.4 -0.3 -0.4 -0.5 -0.2 -0.2 -0.2 -0.2 -1.0 -0.0 -0.2 -0.8 -0.3 -0.3 -0.1 -0.6 -0.7 -0.1 -0.2 -0.5 -0.1 -0.2 -0.7 -1.2 -0.6 -1.2 -0.5 -0.4 -0.7 -0.5 -0.1 -0.8 -0.9
Ever highly irritable/argumentative for 2 days 0.6 0.7 4.0 -0.0 1.0 -0.3 -1.1 0.3 -1.1 -0.2 -0.1 -0.2 -1.1 0.5 -0.8 0.5 0.0 0.8 0.0 -0.8 0.3 0.1 -1.5 -1.1 -1.6 0.8 -2.0 0.2 -1.0 -0.2 -0.9 0.9 0.3 -0.6 -1.2 -0.2 -1.3
Loud music exposure frequency 0.9 1.0 4.8 -0.5 1.4 -0.3 -1.8 0.1 -0.8 -0.2 -1.3 -0.2 -1.0 -0.1 -1.5 0.0 -0.2 0.3 0.9 0.4 -0.3 0.1 -1.9 -1.6 -2.2 0.4 -2.0 -0.6 -1.1 -0.7 -1.1 0.6 0.1 -1.0 -1.1 -0.2 -1.1
Qualifications: O levels/GCSEs or equivalent 0.8 1.2 5.9 1.0 1.2 0.1 0.3 1.7 0.6 1.4 -0.1 1.4 0.9 1.7 0.9 1.7 1.2 1.6 -1.0 0.6 0.2 1.4 -0.6 0.0 -0.5 1.9 -0.7 0.7 0.2 0.9 1.3 1.3 0.7 0.3 -1.1 2.4 0.8
Mouth/teeth dental problems: Bleeding gums 1.8 2.4 7.0 -1.5 -0.5 -1.9 -1.2 -1.2 1.2 -1.2 -1.6 -1.2 -2.0 -0.1 -1.9 -0.5 -1.0 -0.3 1.3 -1.1 -2.7 -1.2 -1.8 -2.5 -1.7 -0.2 -2.2 -2.0 -2.0 -1.7 -1.4 -0.8 -1.3 -1.9 -1.7 -1.1 -1.8
Blood clot in the leg (DVT) 0.5 0.7 3.0 0.1 -0.3 -0.7 1.0 0.8 0.1 -0.1 0.2 -0.1 -0.1 1.7 -0.5 1.4 0.7 1.0 -0.1 -1.1 -0.1 0.3 -1.4 -1.1 -1.1 1.2 -0.8 1.0 -0.7 0.6 0.2 0.6 0.1 0.9 -0.7 0.4 1.4
Medication: Paracetamol 1.5 2.5 7.6 -1.8 -1.4 -1.7 -0.7 -2.2 -1.1 -1.5 -2.3 -1.5 -1.2 -1.9 -1.3 -1.8 -2.2 -2.2 1.8 -0.7 -1.5 -2.2 0.6 -0.4 0.6 -2.1 0.7 -1.9 -0.9 -1.3 -1.3 -2.8 -1.3 -1.7 -0.2 -1.5 -0.8
Headache pain in last month 0.5 0.8 3.4 -0.9 -1.8 -0.3 0.6 -0.6 -0.7 -0.3 -1.2 -0.3 -1.7 -0.8 -0.8 -1.2 -1.4 -0.7 0.6 0.2 -0.8 -0.8 0.3 -0.0 0.3 -0.9 0.1 -1.8 -0.5 -0.4 -0.3 -1.8 -0.3 -1.1 -0.4 -0.6 -1.0
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 2.6 -0.2 1.6 -0.9 -0.4 -0.0 0.8 0.2 -1.4 0.3 -0.2 -0.6 0.0 -0.1 -0.5 -0.1 1.1 0.0 -0.5 -0.5 -0.1 0.0 -0.3 -0.3 -0.1 0.4 -0.1 0.5 -0.6 -0.4 -0.3 -0.2 -0.3 -0.3 -0.3
Glaucoma (self-reported) 0.9 1.1 2.7 -0.9 -0.7 -1.1 0.2 -1.4 -0.7 -1.3 -1.4 -1.3 -1.0 -0.8 -0.3 -0.5 -1.3 -1.6 1.4 -0.7 -1.5 -1.3 0.6 -0.5 0.6 -1.4 0.3 -0.3 -0.9 -0.8 -0.9 -1.6 -1.3 -0.6 -0.4 -1.3 -0.8
Gout (self-reported) 0.7 1.0 5.9 1.0 1.0 -0.1 1.7 1.0 -0.8 0.6 0.4 0.6 0.7 1.2 0.8 2.4 1.9 0.6 -0.5 -0.4 0.4 1.1 -0.6 0.0 -0.2 1.1 -0.5 2.0 -0.3 1.1 -0.8 0.5 -0.5 1.7 -0.4 -0.1 -0.1
Hypothyroidism/myxoedema (self-reported) 1.6 3.2 7.3 2.4 1.1 1.4 1.9 1.9 -0.1 2.1 -0.2 2.1 2.7 1.3 2.3 2.3 2.4 1.6 -0.7 1.4 2.2 1.9 0.9 1.8 0.9 1.7 0.9 2.2 2.1 2.4 1.1 1.6 1.9 1.4 1.5 1.4 2.7
Medication: Amlodipine 0.3 0.4 4.3 -0.2 -2.1 0.6 0.4 -0.3 -0.2 -0.4 1.2 -0.4 0.2 -0.2 -0.2 -0.6 -0.2 -0.3 -0.8 0.0 1.0 -0.1 0.8 0.4 0.9 -0.3 0.5 -1.0 0.4 -0.9 0.5 -0.0 0.6 -0.4 -0.1 -0.2 0.1
Medication: Ventolin 100micrograms inhaler 1.0 1.3 4.1 -1.3 -0.6 -0.3 -0.3 -1.7 -0.6 -1.3 -0.4 -1.3 -1.0 -1.3 0.2 -1.3 -1.5 -1.7 0.4 -0.8 -0.8 -1.4 1.1 -0.1 1.2 -1.6 1.0 -1.6 -0.7 -1.5 -0.2 -2.0 -1.2 -1.6 0.1 -1.1 -1.0
Birth weight 0.2 0.4 1.6 0.7 1.0 0.3 -1.0 0.8 -0.0 0.6 0.2 0.6 1.2 -0.1 0.3 0.4 0.7 0.4 -0.2 0.4 -0.1 0.4 0.2 0.3 0.2 0.3 -0.0 1.2 0.9 0.8 0.1 0.6 0.1 0.7 1.3 0.5 0.8
Chronic bronchitis/emphysema (mother) 1.4 1.6 5.6 -1.2 1.8 -1.7 -0.4 -0.7 1.1 -1.6 -1.7 -1.6 -0.7 -0.8 -1.0 -0.5 -1.0 -1.7 1.9 -1.7 -1.5 -1.4 -1.2 -1.5 -1.1 -1.5 -0.8 0.1 -0.7 -0.8 -1.6 -1.4 -1.1 -0.2 -0.1 -2.4 0.4
High blood pressure (siblings) 0.5 0.7 3.0 -0.7 -1.7 -0.2 -1.6 -1.0 -0.5 -0.8 -0.7 -0.8 0.6 -1.3 -1.1 -1.4 -0.8 -1.1 0.7 0.3 0.4 -0.7 0.5 0.1 0.4 -1.1 0.5 -0.7 0.4 -0.6 -0.6 -0.5 -0.1 -0.3 1.1 -0.9 -0.4
Forced vital capacity (FVC), Best measure 0.1 0.5 2.8 -0.6 -0.3 0.2 -1.7 -0.8 0.3 -0.2 1.3 -0.2 0.3 -1.1 -1.0 -1.4 -0.9 -0.4 -1.0 0.9 -0.2 -0.3 0.1 -0.3 -0.0 -0.6 -0.2 -0.8 0.5 -0.8 0.7 0.1 0.3 -0.6 0.0 0.5 -0.6
Body fat percentage 0.4 1.7 4.5 -0.9 -0.0 -1.2 0.3 -1.0 -2.1 -1.2 -1.6 -1.2 -1.8 -0.4 -0.9 -0.2 -0.7 -0.7 1.8 -1.9 -0.9 -1.2 -1.5 -2.1 -1.6 -0.7 -1.8 -1.1 -1.5 -1.3 -1.9 -1.3 -1.1 -1.3 -0.4 -1.8 -1.1
Leg fat percentage (right) 0.9 3.2 7.0 -1.8 -0.9 -1.7 -1.3 -1.8 -1.3 -1.9 -1.9 -1.9 -2.6 -0.9 -2.2 -1.4 -1.8 -1.4 2.4 -2.1 -1.5 -1.9 -1.4 -2.6 -1.5 -1.3 -1.8 -1.8 -2.0 -2.0 -2.3 -1.9 -1.4 -1.7 0.0 -2.4 -1.2
Arm fat-free mass (right) 0.6 2.9 12.1 -1.6 0.0 -0.7 -1.3 -2.0 -3.1 -1.5 0.8 -1.5 0.1 -3.1 -1.0 -2.2 -1.4 -2.7 1.0 0.4 -0.8 -2.0 0.5 -0.6 0.5 -2.9 0.5 -0.9 0.1 -1.4 -2.4 -2.3 -1.4 -1.2 2.0 -3.5 -1.5
Exposure to tobacco smoke outside home 0.7 0.9 5.2 -0.4 0.1 -0.9 -0.1 -0.6 -0.6 -0.6 -2.3 -0.6 0.6 -1.7 -1.0 -0.8 -0.3 -1.4 1.4 0.4 -0.3 -0.8 -0.3 -0.4 -0.5 -1.3 0.2 -0.1 0.3 0.2 -2.0 -0.6 -0.8 -0.3 0.7 -2.3 -0.4
Comparative body size at age 10 0.1 0.3 2.3 -0.1 0.5 -0.2 -0.8 0.4 0.5 -0.0 -0.5 -0.0 -0.1 0.3 -0.3 0.2 0.2 0.6 0.8 -1.5 -0.1 0.1 -0.8 -0.3 -0.9 0.6 -0.9 -0.7 -0.6 0.1 -0.4 0.4 -0.2 -0.8 -0.7 0.4 -0.1
Number of full brothers 2.0 2.5 7.9 -1.3 -2.4 -2.1 -0.8 -1.9 0.0 -2.1 -1.5 -2.1 -0.1 -2.0 -1.4 -0.9 -0.7 -2.1 1.8 -1.4 -1.0 -2.0 -0.9 -1.4 -0.6 -2.2 -0.5 -0.4 -0.8 -1.6 -2.4 -1.9 -2.0 -1.0 0.2 -2.8 -1.3
Worry too long after embarrassment 1.2 2.0 9.9 1.5 1.4 0.5 1.1 1.7 -0.4 1.7 -3.1 1.7 1.6 1.0 1.2 1.9 1.8 1.5 0.0 1.6 1.3 1.6 -1.0 0.2 -1.1 1.4 -0.2 1.9 1.0 1.9 0.1 1.6 1.1 1.8 1.1 0.8 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 4.2 5.4 12.4 -2.7 -0.8 -3.4 -0.6 -1.8 -1.3 -2.6 -3.5 -2.6 -3.4 -1.0 -1.8 -0.6 -2.4 -1.4 2.9 -2.5 -2.5 -2.6 -1.6 -2.8 -1.4 -1.3 -2.5 -2.1 -3.2 -2.5 -3.1 -2.6 -2.6 -2.2 -2.1 -2.1 -2.3
Wheeze or whistling in the chest in last year 0.1 0.2 1.5 0.2 -0.7 -0.2 0.9 0.0 -1.2 0.1 -0.2 0.1 -0.4 0.6 0.6 0.5 -0.0 0.3 -0.2 -0.2 0.1 0.0 -0.0 -0.3 0.1 0.2 -0.3 0.5 0.0 0.4 0.4 -0.0 0.2 0.5 -0.3 0.1 0.6
Number of children fathered 0.1 0.1 0.7 -0.0 -0.7 -0.5 0.0 -0.1 0.2 0.1 -0.5 0.1 0.8 0.2 0.0 0.2 0.5 -0.1 0.3 -0.0 0.2 0.2 -0.4 -0.8 -0.3 0.1 -0.4 -0.1 0.3 -0.2 -0.2 0.1 -0.2 -0.6 -0.1 -0.6 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 3.7 -0.7 0.5 -1.2 -0.5 -0.6 1.3 -1.1 0.4 -1.1 -0.5 -0.6 -0.8 -0.2 -0.2 -0.9 1.1 -1.9 -0.8 -1.0 -0.7 -0.5 -0.6 -0.7 -0.2 -0.7 -1.2 -0.9 -1.4 -0.8 -1.7 -0.6 -0.5 -1.0 -0.8
Age at first live birth 0.9 1.6 6.2 0.3 1.6 -1.1 0.1 1.5 0.7 0.6 0.7 0.6 -0.1 1.6 -0.4 2.1 1.2 1.8 0.5 -0.9 -0.7 1.0 -2.4 -1.1 -2.3 2.0 -2.5 0.7 -1.1 -0.1 -0.3 1.3 -0.2 0.4 -1.7 1.5 0.2
Pulse wave peak to peak time 2.0 2.3 7.1 1.9 0.4 1.8 1.2 0.9 1.1 1.3 1.8 1.3 2.7 -0.1 1.7 0.5 1.4 0.4 -1.2 1.4 1.8 1.4 1.6 2.0 1.5 0.1 2.0 1.8 2.5 1.5 1.6 1.3 1.6 1.6 2.2 1.0 1.3
Health satisfaction 0.9 1.2 3.6 -1.2 -1.9 -1.2 -0.9 -1.2 -1.2 -1.4 -1.1 -1.3 -1.5 -0.7 -1.2 -1.1 -1.6 -0.7 1.0 -0.5 -1.5 -1.3 -0.2 -0.7 -0.3 -0.7 -0.4 -1.8 -1.2 -1.3 -0.4 -0.9 -1.0 -1.4 -0.7 -0.4 -0.8
Shortness of breath walking on level ground 0.2 0.2 1.3 -0.1 0.3 -1.0 -1.1 -0.2 -0.4 -0.1 0.1 -0.1 0.1 -0.4 -0.2 0.7 0.4 0.1 0.7 -0.1 0.2 -0.4 -0.7 -0.5 -0.5 -0.0 -0.4 0.5 -0.1 0.1 -1.1 0.1 -0.5 0.6 0.5 -0.6 -0.3
Qualifications: College or University degree 0.3 0.9 3.3 -0.5 1.1 -1.4 0.4 -0.0 -1.8 -0.4 0.7 -0.4 0.2 0.7 -0.5 1.0 0.2 0.4 0.2 -1.0 -1.6 0.2 -1.5 -1.0 -1.4 1.0 -1.7 -0.5 -1.0 -0.6 0.3 0.5 -0.8 -0.4 -1.6 1.8 0.0
Eye problems/disorders: None of the above 6.2 7.2 12.9 3.0 1.1 3.2 2.1 3.0 2.0 3.5 2.0 3.5 2.2 2.7 3.1 1.8 2.5 2.8 -2.7 3.1 2.8 3.3 0.7 2.3 0.5 2.5 1.1 2.9 2.9 3.2 3.6 3.0 3.3 2.9 1.4 3.3 3.0
Mouth/teeth dental problems: Loose teeth 0.4 0.4 2.1 0.0 0.6 -0.2 0.2 0.2 0.3 -0.1 -0.6 -0.1 -1.2 1.1 -0.2 0.6 0.1 0.4 0.4 -0.1 -0.2 0.2 -1.2 -1.4 -1.2 0.7 -1.2 0.1 -1.0 -0.3 -0.6 0.2 -0.0 -0.1 -1.1 -0.4 0.4
Emphysema/chronic bronchitis 0.8 0.9 3.0 -0.8 -0.5 -1.1 0.5 -0.9 -1.0 -0.9 -1.4 -0.9 -1.1 -0.4 -0.0 -0.3 -0.7 -0.7 1.2 -1.4 -1.7 -1.1 -0.6 -1.3 -0.7 -0.7 -0.7 -1.0 -1.2 -0.9 -1.0 -1.3 -1.2 -1.3 -0.5 -0.9 -0.7
Medication for pain relief, constipation, heartburn 1.4 2.4 6.2 2.0 2.2 1.3 0.1 1.7 1.8 1.4 0.2 1.4 1.5 1.7 2.0 2.2 2.1 1.9 -1.2 0.9 1.9 1.8 -0.7 0.4 -0.8 2.0 -0.7 2.4 0.8 1.6 1.2 2.5 1.4 1.5 -0.1 1.9 0.6
Neck or shoulder pain in last month 0.3 0.4 1.8 -0.6 -0.2 0.2 -0.4 -0.7 0.6 -0.3 0.2 -0.2 -1.3 -1.0 -0.7 -1.4 -1.0 -0.5 0.2 -0.2 -0.1 -0.7 -0.0 -0.2 -0.2 -0.8 -0.2 -0.9 -0.2 -0.2 -0.7 -0.6 -0.1 -0.8 -0.2 -1.1 -1.3
Medication: Blood pressure 0.3 0.5 3.0 -0.1 -1.7 -0.1 0.2 -0.7 -1.3 -1.0 0.8 -1.0 -0.3 -0.5 -0.7 -0.3 0.0 -0.6 0.2 -0.7 0.3 -0.4 -0.0 -0.3 0.1 -0.5 -0.1 -1.1 -0.3 -1.1 -0.7 -0.4 -0.4 -0.3 0.7 -1.0 -1.0
Angina (self-reported) 0.9 1.1 3.9 0.8 -0.9 1.2 1.1 0.9 0.6 0.4 1.0 0.4 0.8 1.2 0.6 -0.0 0.6 1.0 -1.3 0.8 1.3 1.2 0.4 0.9 0.5 1.0 0.6 -0.2 1.3 0.5 2.0 1.7 1.9 1.1 1.4 1.1 1.7
Migraine (self-reported) 0.5 0.6 2.1 0.9 0.2 0.4 -0.1 1.3 1.2 0.9 0.5 0.9 -0.4 1.4 0.5 1.1 0.8 1.5 -0.6 -0.2 0.5 1.2 -0.6 0.2 -0.6 1.4 -0.8 0.4 -0.1 0.5 0.1 0.9 0.9 0.5 -0.4 0.7 -0.1
Medication: Ibuprofen 0.8 1.0 4.0 0.6 -0.7 1.3 -0.0 1.1 0.4 1.3 1.9 1.4 0.2 0.5 -0.0 -0.2 0.2 1.2 -2.0 1.3 0.7 1.0 1.1 1.4 1.1 0.7 1.0 0.0 1.0 0.3 1.1 0.7 1.1 0.7 1.4 0.9 0.5
Medication: Allopurinol 0.9 1.2 5.3 1.4 0.4 1.0 2.2 0.8 -0.7 1.2 0.7 1.1 1.0 1.1 1.7 2.3 2.0 0.8 -0.8 0.0 0.9 1.4 0.4 0.8 0.7 1.1 0.4 1.5 0.2 1.2 -0.2 0.6 0.1 1.3 -0.4 0.6 -0.1
Medication: Omeprazole 1.8 2.2 7.0 -1.6 0.4 -2.0 -0.5 -1.9 -0.6 -1.7 -1.8 -1.7 -0.7 -1.4 -1.8 -1.2 -1.4 -1.7 2.2 -1.8 -2.6 -1.8 -0.4 -1.3 -0.4 -1.5 -0.3 -1.7 -1.1 -1.1 -1.3 -1.4 -1.8 -1.5 -0.8 -1.4 -1.0
Medication: Seretide 50 evohaler 0.4 0.5 2.0 0.4 -1.4 0.4 0.7 -0.0 -1.3 0.2 0.6 0.2 -0.1 1.1 0.6 -0.3 0.0 0.4 -0.8 0.3 1.1 0.4 -0.3 -0.1 -0.2 0.3 -0.1 0.2 0.7 0.2 1.4 0.7 1.2 0.9 0.0 0.2 1.3
Mean time to correctly identify matches 1.2 2.2 7.9 -1.4 -2.3 -0.5 -0.8 -1.8 -2.8 -1.8 -1.3 -1.8 -1.1 -1.8 -0.1 -1.3 -1.3 -2.1 1.1 -1.6 -0.5 -1.8 0.3 -0.3 0.3 -2.1 0.1 -1.0 -1.1 -1.4 -1.7 -1.9 -1.5 -1.9 -0.8 -2.4 -1.1
Heart disease (mother) 2.7 3.3 9.4 2.0 -0.3 1.1 1.6 2.9 0.4 2.4 1.4 2.4 0.1 2.8 1.4 2.4 1.9 3.1 -1.6 1.1 2.3 2.4 -0.6 0.2 -0.7 2.9 -0.9 1.8 0.7 1.8 1.4 2.2 2.0 1.7 -0.9 2.6 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 2.3 -0.2 -0.9 0.4 -0.5 -0.5 0.9 -0.3 1.0 -0.3 -0.1 -0.3 0.7 -1.1 -0.5 -0.3 -0.2 0.3 0.5 -0.4 1.5 0.5 1.5 -0.6 1.2 -0.4 0.5 -0.6 0.8 -0.6 0.2 -0.6 0.7 -0.4 -0.1
Whole body fat mass 0.5 2.2 7.9 -1.1 0.0 -1.3 -0.4 -1.5 -2.8 -1.5 -1.0 -1.5 -1.4 -1.4 -1.3 -1.0 -1.0 -1.4 1.9 -1.4 -0.9 -1.5 -1.3 -1.9 -1.4 -1.5 -1.4 -1.1 -1.1 -1.5 -2.4 -1.6 -1.2 -1.4 0.5 -2.6 -1.4
Leg fat mass (right) 0.8 3.0 8.7 -1.7 -0.4 -1.6 -1.1 -1.9 -2.4 -1.9 -1.0 -1.9 -1.7 -1.6 -1.9 -1.4 -1.5 -1.8 2.2 -1.7 -1.3 -1.9 -1.3 -2.3 -1.4 -1.7 -1.5 -1.5 -1.5 -1.8 -2.6 -1.9 -1.5 -1.6 0.6 -3.0 -1.6
Arm predicted mass (right) 0.6 3.2 12.7 -1.6 -0.1 -0.7 -1.5 -2.2 -3.1 -1.7 0.9 -1.7 -0.1 -3.3 -1.0 -2.3 -1.5 -2.8 1.1 0.3 -0.8 -2.1 0.4 -0.7 0.3 -3.0 0.4 -1.0 -0.1 -1.5 -2.6 -2.4 -1.4 -1.4 2.1 -3.6 -1.7
Pulse rate, automated reading 1.8 5.9 17.0 -2.8 -1.7 -3.2 -0.6 -1.5 0.6 -3.0 -2.0 -2.9 -3.2 -0.1 -3.0 -1.0 -2.5 -1.3 2.4 -3.5 -2.9 -2.6 -2.6 -4.1 -2.6 -1.0 -3.1 -1.7 -3.4 -2.3 -1.8 -2.2 -2.0 -2.3 -2.9 -1.7 -1.6
Alcohol intake frequency. 0.5 1.1 5.8 -1.2 -1.5 0.5 -0.3 -1.2 0.5 -0.7 -0.6 -0.7 -1.3 -1.5 -1.1 -2.4 -1.8 -1.3 0.6 -0.0 -0.3 -1.1 0.7 -0.7 0.6 -1.8 0.5 -1.4 0.2 -0.7 -0.3 -1.2 0.0 -0.9 0.4 -1.5 -0.7
Comparative height size at age 10 0.6 3.4 12.4 -0.6 0.9 0.2 0.2 -1.8 -1.9 -1.6 2.1 -1.6 1.9 -3.2 0.8 -1.7 -0.4 -3.4 -0.0 1.0 0.0 -1.6 2.1 1.4 2.3 -3.5 3.0 0.1 1.2 -0.5 -1.6 -2.3 -1.2 -0.3 2.8 -3.5 -0.9
Number of full sisters 2.4 2.9 9.0 2.1 -1.0 1.6 2.5 1.9 2.1 1.9 -0.1 1.9 0.7 2.0 1.5 1.5 1.5 1.5 -0.4 1.9 2.0 2.1 0.4 1.1 0.2 1.7 0.4 2.1 1.5 2.5 1.0 1.6 2.2 2.3 0.9 1.1 3.0
Suffer from ‘nerves’ 1.0 1.6 13.4 -0.8 -0.6 -1.6 1.0 -0.8 -2.8 -1.0 -3.7 -1.0 -0.9 -0.9 0.5 -0.1 -0.7 -1.4 1.6 -0.4 -0.6 -1.3 0.4 -0.2 0.6 -1.2 0.8 -0.6 -1.0 -0.6 -1.6 -1.9 -1.6 -0.8 -0.2 -1.8 -0.7
Overall health rating 0.5 1.0 5.2 -0.9 -2.3 0.0 0.2 -0.3 -0.8 -0.5 -1.7 -0.5 -2.2 -0.6 -0.2 -1.6 -1.9 -0.6 1.1 0.3 -0.5 -1.0 1.1 -0.1 0.8 -0.8 0.1 -1.9 -0.5 -0.7 -0.4 -1.3 0.3 -1.1 -0.2 -0.6 -0.4
Chest pain or discomfort 0.4 0.6 2.6 -0.4 -0.9 -0.5 -0.1 -0.1 0.6 -0.7 -0.4 -0.7 -1.5 0.8 -0.2 0.1 -0.4 0.4 0.0 -0.5 0.1 -0.3 -1.6 -1.5 -1.5 0.2 -1.6 -0.5 -1.0 -0.8 -0.1 0.1 -0.0 -0.2 -1.2 -0.2 -0.2
Had major operations 0.6 0.7 4.1 0.2 0.6 -0.6 0.8 0.2 -0.2 0.2 -0.2 0.2 -1.3 1.2 -0.1 1.4 0.4 1.0 -0.2 -1.0 -0.8 0.2 -1.1 -1.1 -0.9 1.1 -1.4 0.1 -1.2 -0.1 -0.2 0.4 -0.6 0.0 -2.0 0.8 -0.6
Age at last live birth 1.4 2.1 8.0 -1.1 1.3 -2.4 -0.1 0.7 0.1 -0.6 -1.0 -0.5 -1.2 0.6 -1.4 1.2 -0.1 0.7 1.7 -2.1 -2.1 -0.4 -2.8 -2.0 -2.6 0.8 -2.8 -0.3 -2.1 -0.7 -1.5 -0.0 -1.6 -0.4 -2.2 0.4 -0.6
Family relationship satisfaction 0.5 0.6 3.0 0.2 -0.3 1.1 0.2 -0.0 -1.5 0.1 -0.1 0.1 0.1 0.2 1.4 -0.0 -0.3 -0.0 -0.8 0.9 0.1 0.3 1.7 1.4 1.7 0.0 1.5 0.1 0.4 0.4 1.3 0.0 0.5 0.1 -0.1 1.0 0.3
Leg pain on walking 1.2 1.5 5.7 -1.1 -0.9 -1.5 -0.3 -0.8 -1.4 -1.1 -0.5 -1.1 -2.1 -0.5 -1.2 0.3 -0.7 -0.8 1.7 -1.4 -1.4 -1.1 -1.0 -1.5 -0.8 -0.6 -1.2 -0.6 -2.0 -1.1 -2.4 -1.5 -1.6 -0.5 -1.0 -1.6 -1.3
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 5.2 -1.1 -0.4 -1.5 -1.6 -0.1 -0.2 -0.8 -1.2 -0.7 -1.1 -0.9 -1.5 -0.4 -0.8 -0.6 2.2 -1.1 -1.6 -1.0 -1.2 -1.0 -1.4 -0.5 -1.2 -0.7 -1.4 -1.0 -2.3 -1.0 -1.6 -0.6 -0.5 -1.4 -1.1
Commuting to job workplace: Car/motor vehicle 1.4 1.6 7.9 -1.2 -1.7 -1.2 -1.1 -0.7 -2.8 -1.1 0.0 -1.0 -0.9 -1.6 -2.2 -1.2 -1.2 -0.8 2.0 -1.4 -0.8 -1.5 -0.4 -0.5 -0.6 -0.8 -0.5 -1.7 -1.1 -0.9 -1.8 -1.0 -1.1 -1.5 0.3 -0.5 -1.5
Illness, injury, bereavement, stress in last 2 years 4.0 4.9 8.3 2.9 2.4 2.0 1.5 2.2 -0.9 2.5 0.6 2.5 2.9 1.5 2.3 2.2 2.8 2.1 -2.2 1.8 2.7 2.6 0.9 2.9 0.9 2.0 1.4 2.1 2.5 2.7 1.9 2.6 2.5 2.7 2.5 2.3 2.2
Medication: Aspirin 0.7 0.9 6.0 -0.5 -2.4 0.8 0.6 -1.2 -1.7 -0.7 0.9 -0.7 -0.7 -0.6 -0.4 -1.6 -0.9 -1.1 -0.6 0.4 0.4 -0.3 1.2 0.7 1.2 -1.1 1.2 -1.8 0.3 -0.9 0.7 -0.9 0.2 -0.3 0.6 -0.6 0.3
Supplements: Vitamin C 0.2 0.2 1.0 -0.2 -0.5 0.2 -0.1 -0.3 0.9 -0.2 -0.6 -0.2 0.0 -1.0 0.3 -0.4 -0.4 -0.5 0.2 0.3 0.4 -0.5 0.5 0.5 0.4 -0.6 0.6 -0.2 0.2 -0.1 -0.5 -0.4 0.2 -0.4 1.0 -0.6 -0.2
Knee pain experienced in last month 0.9 1.3 3.3 -0.9 -0.7 -0.4 -1.8 -0.5 1.8 -0.8 -1.3 -0.7 -1.4 -1.8 -1.6 -1.8 -1.5 -0.9 1.6 -0.2 -0.9 -1.1 -0.7 -0.8 -1.2 -1.2 -0.7 -1.5 -0.4 -0.5 -1.8 -0.6 -0.2 -0.9 0.9 -1.5 -1.3
Hypertension (Self-reported) 0.3 0.8 9.6 -0.7 -3.1 -0.2 0.1 -1.0 -0.5 -0.8 -1.1 -0.8 -0.4 -0.3 -1.3 -1.1 -0.7 -0.3 -0.1 -0.1 0.7 -0.6 0.3 -0.4 0.4 -0.4 -0.1 -2.0 -0.2 -1.3 0.3 -0.3 0.0 -1.1 -0.2 0.1 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 3.9 -0.6 -0.5 0.1 0.4 -1.6 -1.4 -0.7 0.3 -0.7 0.7 -1.5 0.4 -1.3 -0.6 -1.8 0.5 0.3 -0.7 -1.1 1.7 0.7 1.8 -2.0 1.9 -0.5 0.6 -0.6 0.1 -1.7 -0.9 -0.6 1.1 -1.8 -0.1
Illnesses of father: Heart disease 6.3 8.7 18.7 3.3 1.6 2.7 1.1 3.6 2.6 3.4 0.9 3.4 3.0 3.6 2.2 2.8 3.4 3.8 -3.4 2.3 3.0 3.9 -0.3 1.5 -0.3 3.8 -0.1 3.3 2.7 3.1 3.4 4.3 3.6 3.4 1.1 3.7 3.5
Illnesses of siblings: Diabetes 0.2 0.3 1.0 0.2 -0.1 -0.2 0.2 0.4 0.3 0.6 -1.0 0.6 -0.1 0.1 0.0 0.7 0.4 0.3 0.9 -0.3 0.2 0.3 -0.8 -0.1 -1.0 0.6 -0.7 0.2 -0.5 0.4 -0.9 0.2 -0.2 -0.6 -0.7 0.2 -0.2
Smoking status: Previous 1.0 1.6 6.9 -1.3 0.7 -1.9 -0.9 -0.1 -0.2 -0.8 -0.0 -0.8 -1.6 0.1 -0.9 0.7 -0.5 -0.1 0.7 -1.8 -1.6 -1.1 -1.6 -2.0 -1.4 0.1 -1.8 -0.5 -1.9 -1.1 -1.6 -1.1 -1.6 -1.5 -2.6 -0.9 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 10.9 -0.1 1.0 0.6 -0.3 -0.2 -3.3 0.1 2.0 0.1 0.9 -1.9 0.2 -1.0 0.1 -0.9 -0.4 1.3 0.0 -0.3 0.8 1.0 0.8 -1.4 0.6 -0.6 1.0 -0.6 -1.0 -1.0 -0.3 -0.5 1.7 -1.3 -1.0
Whole body fat-free mass 0.5 2.8 11.4 -1.3 0.6 -0.9 -1.3 -2.0 -3.4 -1.5 1.0 -1.5 0.5 -3.1 -1.0 -1.7 -0.9 -2.6 1.2 0.2 -0.9 -1.8 0.1 -0.6 0.1 -2.7 0.4 -0.6 0.1 -1.3 -2.7 -2.0 -1.6 -1.2 1.8 -3.4 -1.6
Leg fat-free mass (right) 0.4 1.9 11.8 -0.8 0.9 -1.1 -0.8 -1.3 -3.4 -1.0 0.3 -1.0 0.4 -2.4 -1.0 -0.9 -0.4 -1.7 1.3 -0.2 -0.7 -1.4 -0.7 -0.8 -0.8 -1.8 -0.5 -0.4 -0.2 -0.9 -2.8 -1.4 -1.3 -1.1 1.2 -2.7 -1.5
Arm fat percentage (left) 0.4 1.5 4.8 -0.7 -0.2 -1.1 0.1 -1.1 -2.2 -1.0 -1.9 -0.9 -1.4 -0.7 -0.9 -0.3 -0.6 -0.6 1.9 -1.5 -0.7 -1.1 -1.2 -1.7 -1.3 -0.7 -1.5 -1.1 -1.2 -1.1 -1.9 -1.2 -0.9 -1.3 0.0 -1.7 -1.1
Average weekly red wine intake 0.4 0.6 2.9 0.5 -0.1 0.1 1.7 0.3 1.0 0.5 -0.6 0.5 0.6 1.0 0.5 0.7 0.6 0.4 -0.4 0.7 0.2 0.7 -0.7 -1.0 -0.6 0.4 -0.6 0.7 0.4 0.6 1.1 0.6 0.3 0.5 -1.6 1.2 1.4
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.5 0.5 -0.7 -0.4 0.3 0.9 0.4 0.7 -1.2 0.7 0.3 0.4 0.4 0.9 0.4 0.9 0.7 -0.2 1.6 0.3 -0.5 0.4 -0.7 0.9 -0.5 0.7 0.2 1.1 -0.0 0.8 0.7 0.1 -0.7 0.6 -0.0
Mood swings 0.7 1.2 7.7 0.8 0.5 1.0 0.7 0.7 -1.4 1.1 -1.9 1.1 0.5 -1.0 1.1 -0.6 0.0 0.2 0.0 2.2 1.6 0.4 1.3 1.7 1.0 -0.4 1.3 0.4 1.6 1.2 -0.2 -0.0 1.1 0.6 2.8 -0.6 -0.1
Loneliness, isolation 1.0 1.4 6.2 -1.6 -0.3 -1.2 -1.3 -0.9 -1.1 -1.3 -2.5 -1.3 -0.8 -1.4 -1.3 -1.5 -1.6 -1.0 1.7 -0.6 -1.2 -1.2 -0.4 -0.8 -0.5 -1.0 -0.5 -1.4 -0.7 -1.2 -1.4 -0.9 -0.7 -1.1 0.5 -1.4 -1.0
Long-standing illness, disability or infirmity 0.3 0.5 3.5 -0.0 -0.3 0.4 1.2 0.2 1.0 0.1 -1.9 0.1 -0.3 -0.1 1.0 -0.5 -0.6 -0.2 0.3 0.5 0.7 -0.4 1.5 0.6 1.4 -0.4 0.9 -0.2 0.6 0.4 0.8 -0.6 0.6 -0.4 0.1 0.1 0.9
Ever had bowel cancer screening 0.2 0.3 2.0 -0.1 -0.1 -0.2 -0.2 -1.4 -0.4 -0.6 -0.0 -0.7 0.3 -0.4 0.1 0.0 -0.2 -0.9 0.6 -0.6 -0.1 -0.7 0.3 0.1 0.5 -0.9 1.0 0.3 0.0 -0.4 0.1 -0.5 -0.6 0.0 -0.7 -0.4 0.3
Diabetes diagnosed by doctor 0.7 1.2 6.4 0.1 -0.1 -0.7 0.6 1.0 -0.4 0.2 -1.0 0.2 -0.2 1.4 -0.9 1.4 1.1 1.1 1.0 -0.5 -0.0 0.7 -2.5 -1.9 -2.4 1.3 -2.4 0.7 -0.8 0.1 -0.8 0.9 -0.1 0.3 -1.3 -0.0 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.8 3.9 -0.2 0.4 -1.0 0.2 -0.6 -1.1 -1.2 -0.5 -1.3 -0.0 -0.6 -0.1 0.0 0.1 -1.1 0.5 -0.9 -1.3 -0.7 -1.1 -1.1 -0.9 -1.1 -0.7 0.4 -0.5 -0.8 -1.3 -0.4 -1.4 0.2 -1.3 -2.0 -0.8
Friendships satisfaction 0.4 0.5 3.8 -0.3 -0.5 -0.3 -0.5 -0.4 -0.9 0.3 -1.9 0.3 -1.2 0.3 0.3 0.5 -0.5 0.6 -0.1 0.3 -1.0 0.1 0.5 0.6 0.6 0.7 0.0 -0.5 -0.9 -0.2 -0.0 -0.2 -0.5 -0.6 -1.1 1.1 -1.2
Qualifications: nursing, teaching 0.5 0.8 6.2 0.3 -0.4 0.0 -0.2 0.7 0.0 1.2 -1.2 1.3 1.1 0.6 0.4 0.2 0.1 1.1 0.4 0.8 0.8 0.5 -0.0 -0.1 -0.3 1.0 -0.1 0.0 0.8 1.3 1.5 0.8 0.9 -0.7 -0.3 2.5 1.4
Commuting to job workplace: Walk 0.9 1.0 6.7 0.9 0.8 0.6 2.6 -0.3 2.2 0.2 -0.1 0.1 0.3 1.1 2.5 0.8 0.6 -0.2 -0.5 0.3 1.2 0.4 0.5 0.4 0.7 0.0 0.5 1.3 0.7 1.1 1.3 0.1 1.0 1.0 -0.2 0.0 0.4
Eye problems/disorders: Cataract 5.0 5.8 11.0 -3.0 -1.5 -2.4 -2.5 -3.0 -1.9 -3.0 -1.4 -3.0 -1.7 -2.9 -3.3 -2.4 -2.5 -2.7 2.3 -2.0 -2.4 -2.9 -0.8 -2.2 -0.7 -2.5 -1.1 -2.8 -2.1 -3.0 -2.4 -2.5 -2.6 -3.0 -1.6 -2.3 -2.6
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 5.7 -0.3 -0.2 -1.4 0.6 -1.1 -0.4 -0.9 -2.4 -0.9 0.6 -0.7 -0.5 0.2 0.2 -1.0 0.9 -1.4 -1.1 -1.0 -0.6 -0.5 -0.4 -0.9 0.1 0.2 -0.3 -0.2 -0.9 -0.9 -1.2 -0.2 -0.9 -1.0 -0.1
Medication for cholesterol 0.5 0.8 2.7 0.2 1.6 -0.7 0.2 0.1 -0.8 -0.7 1.0 -0.7 0.5 -0.2 0.7 1.3 1.1 -0.5 0.2 -1.4 -0.8 -0.1 -1.4 -0.8 -1.2 -0.2 -1.0 1.1 -0.8 -0.3 -1.4 -0.3 -1.3 0.1 0.1 -1.3 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.8 3.3 8.3 -2.2 -1.6 -2.3 -0.9 -1.4 -1.7 -2.1 -1.5 -2.0 -1.1 -2.3 -2.9 -1.7 -1.9 -1.5 2.5 -1.9 -1.7 -2.4 -1.2 -1.6 -1.3 -1.8 -0.8 -1.6 -1.4 -1.7 -2.6 -1.8 -1.8 -1.5 -0.6 -2.3 -1.6
Back pain experienced in last month 0.2 0.3 2.2 -0.1 -1.2 -0.4 0.5 0.7 -1.5 -0.1 1.0 -0.1 -1.0 0.4 -0.3 0.3 -0.3 0.4 0.3 -0.7 0.0 -0.1 -0.3 -0.5 -0.4 0.5 -0.7 -0.2 -0.6 0.3 -0.7 0.0 0.2 -0.0 -0.4 -0.1 -0.5
Mineral and other dietary supplements 0.1 0.1 0.6 -0.1 0.4 -0.6 0.5 -0.2 -0.2 -0.4 0.5 -0.4 0.7 0.1 0.3 0.5 0.3 -0.2 0.1 -0.7 -0.3 -0.1 -0.6 -0.3 -0.4 -0.2 -0.1 0.2 -0.0 -0.1 0.0 -0.1 -0.6 0.5 0.6 -0.4 0.1
Breast cancer (self-reported) 0.5 0.6 2.1 0.9 0.5 1.4 0.7 1.0 0.4 1.3 0.7 1.3 -0.1 0.5 1.4 1.0 0.9 1.1 -0.5 0.9 1.3 0.9 0.4 0.5 0.2 0.9 -0.1 0.5 0.1 0.7 0.0 0.3 0.6 -0.5 -0.7 0.7 -0.2
Asthma (self-reported) 1.0 2.0 4.2 -1.6 -1.1 -1.6 -1.9 -2.0 -2.1 -1.9 0.1 -1.9 -1.0 -1.3 -1.9 -1.2 -1.6 -1.5 1.5 -1.6 -1.1 -1.9 -0.3 -1.3 -0.2 -1.3 -0.7 -1.8 -1.2 -1.8 -1.1 -1.3 -1.2 -1.7 0.2 -1.3 -1.1
Osteoporosis (self-reported) 0.5 0.6 2.7 0.1 -0.4 1.0 0.4 0.6 0.6 0.8 -1.4 0.8 -0.3 -0.5 0.5 -1.1 -1.0 -0.1 0.6 1.4 0.6 0.1 1.6 0.8 1.2 -0.2 1.1 -0.3 0.9 0.8 0.5 -0.5 1.1 -0.4 0.9 0.8 0.3
Osteoarthritis (self-reported) 1.8 2.4 6.3 -1.5 -2.2 -0.6 -0.4 -2.5 -1.3 -1.2 -1.8 -1.2 -1.4 -2.0 -0.6 -1.9 -2.0 -2.1 1.1 -0.6 -0.9 -1.9 1.6 -0.1 1.6 -2.0 1.0 -1.9 -0.7 -1.6 -0.6 -2.5 -1.3 -2.5 -0.3 -1.3 -1.0
Medication: Aspirin 0.9 1.1 8.2 -0.7 -2.9 0.6 0.1 -1.4 -1.7 -1.0 0.9 -1.1 -0.9 -0.8 -0.8 -1.9 -1.2 -1.3 -0.4 0.1 0.2 -0.6 0.9 0.4 0.9 -1.3 1.1 -1.9 0.2 -1.2 0.6 -0.8 0.1 -0.3 0.3 -0.8 -0.0
Medication: Gliclazide 2.3 2.6 7.1 1.4 0.0 1.1 1.3 2.5 1.3 1.7 0.0 1.7 0.0 2.6 1.0 2.3 1.7 2.7 -1.0 0.9 1.5 2.0 -1.4 0.1 -1.4 2.7 -1.0 1.8 0.1 1.5 1.2 2.1 1.6 1.9 0.2 2.1 1.6
Illnesses of father: None of the above (group 1) 1.2 1.5 3.8 -1.5 0.6 -1.3 -1.1 -0.6 -1.4 -1.2 -0.5 -1.1 -1.3 -1.3 -1.7 -0.9 -1.3 -1.1 1.7 -0.7 -1.8 -1.3 -0.5 -1.1 -0.7 -0.9 -0.6 -1.5 -1.6 -0.9 -1.9 -1.2 -1.6 -1.3 -0.7 -0.9 -1.8
Smoking status: Current 0.2 0.4 1.4 -0.0 -0.7 0.2 0.3 0.1 1.1 -0.1 -0.7 -0.1 -0.3 -0.5 0.0 -1.0 -0.6 -0.3 1.0 0.7 0.8 -0.4 -0.4 -0.2 -0.8 -0.7 -0.3 -0.1 0.5 0.7 -0.6 0.1 0.8 0.3 1.2 -0.8 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.4 7.4 -2.0 -2.5 -1.0 -1.8 -2.0 0.2 -1.7 -0.9 -1.7 -1.5 -1.6 -2.4 -2.7 -2.3 -1.5 1.0 -1.1 -1.3 -1.7 0.0 -1.1 -0.1 -1.5 -0.4 -2.7 -0.8 -2.3 -0.3 -1.5 -0.8 -1.9 -0.2 -0.8 -1.3
Whole body water mass 0.4 2.4 11.3 -1.1 0.7 -0.8 -1.1 -1.8 -3.4 -1.3 1.0 -1.3 0.7 -2.9 -0.8 -1.5 -0.7 -2.4 1.0 0.4 -0.7 -1.6 0.2 -0.4 0.2 -2.5 0.4 -0.4 0.2 -1.1 -2.6 -1.9 -1.4 -1.0 1.9 -3.2 -1.4
Leg predicted mass (right) 0.4 1.9 11.2 -0.9 0.9 -1.1 -0.8 -1.3 -3.4 -1.1 0.3 -1.1 0.4 -2.4 -1.0 -0.9 -0.4 -1.7 1.3 -0.3 -0.7 -1.4 -0.7 -0.7 -0.8 -1.8 -0.5 -0.5 -0.2 -0.9 -2.8 -1.4 -1.3 -1.1 1.2 -2.7 -1.5
Arm fat mass (left) 0.6 2.3 7.5 -1.2 -0.1 -1.3 -0.5 -1.7 -2.6 -1.4 -1.4 -1.4 -1.3 -1.6 -1.3 -1.0 -1.0 -1.5 2.0 -1.3 -0.9 -1.6 -1.1 -1.9 -1.2 -1.6 -1.3 -1.3 -1.1 -1.6 -2.7 -1.8 -1.3 -1.7 0.7 -2.7 -1.7
Number of self-reported non-cancer illnesses 0.3 0.5 6.6 -0.3 -1.8 0.2 -0.0 -0.4 -0.4 -0.1 -2.6 -0.0 -0.5 -0.2 -0.4 -0.6 -0.6 0.1 0.3 0.3 0.5 -0.4 0.6 -0.1 0.5 -0.1 0.2 -1.3 0.1 -0.7 0.5 -0.3 0.4 -1.2 -0.2 0.2 0.3
Average weekly champagne plus white wine intake 0.6 0.9 5.1 -0.3 0.9 -1.3 -1.2 0.3 0.1 0.1 0.6 0.1 -0.7 1.4 -0.8 1.1 0.1 1.1 0.1 -1.2 -1.3 0.2 -1.2 -1.0 -1.1 1.5 -1.1 0.5 -1.2 0.1 0.2 0.8 -0.4 0.4 -2.3 1.5 -0.4
Miserableness 1.5 2.7 9.3 -1.8 0.7 -2.2 -1.4 -1.2 -2.9 -1.5 -2.8 -1.5 -1.3 -1.8 -1.2 -1.1 -1.7 -1.5 3.0 -1.2 -0.7 -1.7 -0.2 -0.7 -0.3 -1.5 -0.3 -1.5 -1.1 -0.9 -2.5 -1.9 -1.3 -1.3 1.0 -2.5 -1.7
Guilty feelings 0.3 0.4 4.6 -0.1 0.8 -0.4 -1.0 0.9 0.1 0.7 -2.1 0.7 -0.1 0.0 -0.6 0.2 0.0 0.7 0.5 0.9 -0.2 0.6 -0.3 -0.6 -0.5 0.7 -0.8 0.2 -0.1 0.4 -0.8 0.6 0.2 -0.0 0.1 0.0 -0.4
Wears glasses or contact lenses 0.8 0.9 6.0 -1.0 -0.7 -0.5 -0.7 -0.8 1.5 -0.4 -2.4 -0.4 -0.6 -0.8 -0.4 -1.6 -1.7 -0.8 0.7 0.5 -0.1 -1.1 1.7 0.3 1.6 -0.9 0.9 -0.9 0.4 -0.1 0.5 -0.9 0.4 -0.6 0.9 0.1 0.4
Ever taken oral contraceptive pill 1.2 1.4 4.5 1.2 2.1 0.9 0.7 1.4 1.4 1.8 -0.3 1.8 1.0 0.8 0.9 0.8 0.9 1.6 -0.7 1.6 0.3 1.2 -0.3 0.4 -0.6 1.4 -0.4 0.9 1.2 1.3 1.4 1.4 1.3 0.7 0.5 2.0 1.1
Hearing aid user 0.6 0.6 3.9 -0.1 -0.2 -0.5 1.0 0.2 0.5 -0.2 -2.0 -0.2 -0.1 0.6 -1.0 0.4 0.1 0.2 0.7 -0.1 -0.6 0.1 -1.6 -1.4 -1.7 0.4 -1.1 0.2 -0.5 0.4 -0.2 0.6 0.1 0.4 -1.6 0.4 0.8
Mother’s age at death 0.6 0.8 2.4 -0.2 0.5 -0.8 -0.5 1.5 1.0 0.4 0.8 0.4 -0.5 1.3 -0.5 1.3 0.3 1.2 0.7 -0.8 -1.0 0.5 -1.1 -1.2 -1.0 1.3 -1.3 0.7 -1.0 0.4 -0.4 0.6 -0.5 0.4 -1.4 1.0 0.6
Financial situation satisfaction 1.1 1.4 3.3 -1.3 -1.4 -1.3 -0.5 -1.0 -0.8 -1.6 -1.7 -1.6 -1.2 -0.6 -1.2 -0.4 -1.1 -0.9 0.6 -1.2 -1.8 -1.3 -0.5 -1.2 -0.3 -0.9 -0.5 -1.1 -1.6 -1.2 -1.2 -1.2 -1.6 -1.0 -1.6 -0.8 -1.4
Tinnitus: Yes, now most or all of the time 0.4 0.5 2.1 -0.3 -0.7 -1.2 0.2 0.1 0.1 -0.2 -0.9 -0.2 -0.7 0.5 0.3 0.8 0.0 -0.1 1.4 -1.0 -1.4 -0.2 -0.4 -0.5 -0.4 0.2 -0.5 0.4 -1.1 0.2 -0.8 -0.8 -1.0 -0.1 -1.0 0.1 -0.7
Commuting to job workplace: Public transport 0.5 0.6 6.9 0.2 0.1 -0.2 0.9 0.2 2.6 -0.0 -0.7 -0.0 -0.3 0.8 -0.1 0.2 -0.0 0.7 -0.1 -0.1 -0.2 0.1 -1.4 -1.2 -1.5 0.5 -1.2 0.2 0.0 0.4 0.8 0.8 0.7 0.5 -1.1 0.9 0.7
Eye problems/disorders: Glaucoma 2.1 2.4 5.2 -1.6 -1.2 -1.7 -0.6 -2.1 -0.5 -2.1 -0.3 -2.1 -1.6 -1.1 -0.7 -1.0 -1.7 -1.9 1.4 -2.0 -1.9 -1.9 0.2 -1.0 0.3 -1.5 -0.3 -1.7 -1.9 -2.3 -1.3 -2.0 -2.0 -2.0 -1.1 -1.8 -2.0
Medication: Blood pressure 0.6 1.1 5.0 -0.3 -1.8 0.4 1.0 -0.3 1.1 0.5 -2.2 0.6 -0.3 0.1 -0.4 -1.3 -1.2 0.2 -0.1 1.1 0.9 -0.1 1.7 0.6 1.6 0.0 1.0 -1.5 1.0 0.2 1.7 0.1 1.5 -0.3 0.0 1.6 1.4
Pain type(s) experienced in last month: Hip pain 0.5 0.7 2.1 1.0 -1.4 0.5 0.7 1.0 0.3 0.8 0.5 0.8 0.1 1.2 0.5 1.1 1.0 1.3 -0.7 0.3 1.5 1.0 -0.5 -0.0 -0.5 1.2 -0.4 0.7 0.4 0.7 0.4 0.9 1.1 0.8 0.3 1.0 0.5
Supplements: Fish oil (including cod liver oil) 0.2 0.2 1.4 -0.4 -0.9 -0.1 -0.7 0.1 -0.6 -0.0 -0.4 -0.0 -1.2 -0.2 -0.8 -0.7 -0.7 0.0 0.3 0.1 -0.4 -0.2 -0.0 -0.3 -0.2 0.0 -0.4 -0.7 -0.5 -0.6 -0.5 -0.1 -0.0 -0.6 -0.4 -0.3 -0.5
High cholesterol (Self-reported) 0.6 1.0 5.1 -0.9 -2.3 0.2 0.4 -1.5 0.9 -1.1 -0.8 -1.1 0.4 -1.1 -0.1 -2.1 -1.2 -1.5 0.2 0.3 0.6 -0.9 0.7 0.1 0.7 -1.6 0.9 -1.6 0.8 -0.7 0.9 -0.6 0.3 -0.8 1.1 -0.7 0.5
Medication: Bendroflumethiazide 0.6 0.9 4.9 -0.7 -1.0 -0.1 -1.0 -0.8 -0.1 -0.6 -1.0 -0.6 -0.3 -1.3 -1.4 -1.9 -1.4 -0.5 1.0 0.2 0.6 -1.0 0.3 -0.4 0.1 -0.8 -0.2 -2.2 0.3 -1.1 -0.1 -0.3 0.6 -1.6 1.4 -0.2 -0.5
Medication: Paracetamol 1.2 1.8 5.7 -1.4 -1.7 -0.8 -0.2 -2.1 -0.8 -1.0 -1.3 -1.0 -0.8 -1.7 -1.0 -2.0 -2.2 -1.9 1.1 -0.1 -0.9 -1.8 1.6 0.4 1.6 -1.9 1.5 -1.9 -0.1 -0.9 -0.4 -2.4 -0.4 -1.5 0.4 -0.7 -0.2
Medication: Lisinopril 0.4 0.5 1.7 -1.0 -0.5 -0.4 0.7 -0.8 -0.4 -0.6 -1.3 -0.5 -0.7 -0.5 -0.9 -1.0 -1.3 -0.5 0.9 -0.6 -0.7 -0.8 0.3 -0.2 0.2 -0.6 0.0 -1.2 -0.5 -0.6 0.3 -0.8 -0.3 -0.9 -0.9 0.6 -0.1
Medication: Atorvastatin 0.6 0.8 10.1 -0.6 -3.2 0.8 -0.5 -0.3 -0.1 0.6 -0.8 0.6 -0.0 -0.7 -0.4 -1.3 -1.0 -0.1 0.2 0.7 0.4 0.0 1.4 0.5 1.2 -0.2 0.6 -1.1 0.7 0.2 0.5 -0.4 1.0 -1.1 0.2 0.6 0.1
Illnesses of father: High blood pressure 1.3 1.6 7.1 -1.4 -2.7 -1.0 0.1 -1.8 -0.8 -1.5 -0.6 -1.5 -0.7 -1.2 -0.9 -1.9 -1.7 -1.8 1.2 -1.0 -1.1 -1.8 0.8 -0.2 0.8 -1.9 0.7 -1.6 -0.3 -1.0 0.3 -1.9 -1.1 -1.3 0.1 -0.9 -0.1
Alcohol drinker status: Never 1.7 2.0 7.4 -1.2 -1.6 0.3 -0.8 -1.8 -0.5 -1.1 -0.3 -1.1 0.7 -2.7 -0.8 -2.6 -1.6 -2.3 0.5 -0.1 0.1 -1.4 1.8 0.7 1.8 -2.6 2.3 -1.4 1.1 -0.6 -0.2 -1.5 -0.3 -0.4 2.1 -1.7 -0.1
Ever smoked 0.4 0.7 2.8 1.1 1.1 0.5 0.9 1.2 0.5 1.0 0.0 1.0 0.1 0.9 1.2 1.7 1.2 1.1 -0.5 0.3 0.5 0.8 -0.7 0.3 -0.7 0.9 -0.5 1.2 0.2 0.8 -0.1 0.6 0.5 0.3 -0.5 0.3 1.2
Basal metabolic rate 0.5 2.5 11.6 -1.1 0.6 -0.8 -1.2 -1.9 -3.4 -1.3 0.8 -1.4 0.5 -2.9 -1.0 -1.6 -0.8 -2.4 1.2 0.2 -0.7 -1.7 -0.0 -0.6 -0.0 -2.5 0.2 -0.6 0.1 -1.2 -2.6 -1.9 -1.4 -1.2 1.9 -3.3 -1.5
Leg fat percentage (left) 1.2 4.4 10.1 -2.2 -1.0 -2.1 -1.6 -1.9 -1.6 -2.1 -2.0 -2.1 -3.0 -1.0 -2.7 -1.4 -2.0 -1.4 2.7 -2.5 -1.8 -2.1 -2.0 -3.2 -2.0 -1.3 -2.4 -2.1 -2.5 -2.3 -2.8 -2.0 -1.8 -2.1 -0.5 -2.7 -1.7
Arm fat-free mass (left) 0.5 2.6 11.8 -1.3 0.3 -0.6 -1.4 -1.9 -2.8 -1.4 1.2 -1.4 0.1 -2.9 -0.9 -1.9 -1.1 -2.5 0.9 0.3 -0.7 -1.8 0.5 -0.5 0.5 -2.7 0.5 -0.7 0.0 -1.4 -2.5 -2.1 -1.4 -1.3 2.0 -3.4 -1.6
Number of operations (self-reported) 1.3 1.9 4.9 -1.5 -1.1 -1.7 -0.8 -1.8 -1.6 -1.3 -1.7 -1.3 -1.5 -1.1 -1.1 -0.5 -1.2 -1.3 0.9 -1.1 -1.8 -1.8 0.2 -1.0 0.4 -1.3 0.1 -1.5 -1.6 -1.4 -1.6 -1.8 -2.2 -1.6 -2.1 -1.4 -1.3
Average weekly beer plus cider intake 0.6 0.9 3.6 0.9 1.9 -0.2 -0.8 1.1 -1.4 0.5 1.4 0.5 0.1 0.6 -0.3 1.4 1.4 1.1 -0.5 -0.7 0.8 0.6 -1.6 -0.2 -1.6 1.2 -1.5 0.8 -0.4 0.1 -1.1 1.0 0.1 0.5 0.8 -0.1 -0.7
Irritability 0.6 1.1 4.1 -0.6 -0.9 -1.2 -0.2 0.0 -1.9 -0.4 -1.9 -0.4 -0.8 -1.3 -1.4 -0.8 -0.5 -0.3 1.6 -0.3 -0.4 -0.7 -1.2 -0.7 -1.4 -0.6 -1.1 -0.8 -0.5 -0.8 -1.9 -0.9 -0.8 -0.3 2.0 -1.1 -0.8
Risk taking 0.7 1.1 4.9 0.4 0.4 0.4 -1.1 0.7 1.8 0.9 2.2 0.9 -0.8 1.1 -0.3 0.3 0.5 1.3 -1.3 0.8 0.3 0.8 -1.9 -0.9 -1.9 1.1 -1.8 0.6 0.1 0.1 0.1 1.2 1.0 0.7 -0.9 0.2 0.4
Ever had prostate specific antigen (PSA) test 0.3 0.4 2.9 -0.3 0.1 -0.1 -1.7 -0.5 -0.1 0.0 -1.0 0.0 0.8 -0.8 -0.6 -0.8 -0.3 -0.4 1.0 0.6 -0.5 -0.0 0.0 -0.2 -0.1 -0.3 0.1 -0.2 0.6 -0.2 -0.2 0.5 0.0 0.1 1.6 -0.3 0.3
Fractured/broken bones in last 5 years 0.4 0.5 2.6 -0.3 0.8 -1.6 -0.2 0.1 -0.3 -0.1 -0.6 -0.1 0.2 0.0 -0.9 1.0 0.3 0.3 0.6 -0.6 -1.2 -0.2 -1.3 -1.2 -1.2 0.4 -0.9 0.2 -0.7 -0.1 -1.1 0.1 -1.0 -0.0 -0.9 -0.3 -0.1
Age started oral contraceptive pill 0.5 0.6 2.2 -0.6 -0.9 -0.7 -0.2 -0.8 0.4 -1.2 -1.0 -1.2 -0.8 0.3 -0.1 -0.5 -0.9 -0.6 0.1 -1.5 -1.2 -0.8 0.7 -0.4 0.9 -0.3 -0.1 -1.0 -0.9 -1.3 0.5 -0.7 -0.7 -0.9 -0.9 0.0 0.3
Diastolic blood pressure, automated reading 1.2 3.7 10.1 -2.1 -3.2 -1.4 -2.5 -1.5 -0.1 -1.8 -2.5 -1.8 -1.9 -1.8 -2.8 -2.2 -2.3 -1.1 1.4 -1.2 -1.6 -2.0 -0.8 -1.8 -1.0 -1.4 -1.7 -2.9 -1.6 -3.1 -1.4 -1.8 -1.4 -3.1 -0.5 -1.5 -2.0
Ever depressed for a whole week 1.2 1.5 7.8 -1.4 -1.9 -1.2 -0.6 -0.1 -0.6 -0.8 -0.7 -0.8 -2.0 1.2 -1.1 -0.2 -1.3 0.6 0.5 -1.2 -1.5 -0.4 -1.0 -2.1 -1.0 0.8 -1.7 -1.4 -1.9 -1.0 0.5 -0.1 -0.5 -1.7 -2.8 1.0 -0.8
Unable to work because of sickness or disability 0.2 0.3 1.4 -0.5 -0.3 -0.9 0.4 0.4 -0.3 -0.7 -0.7 -0.6 -1.1 0.0 -0.2 0.3 -0.6 -0.1 1.0 -0.1 -0.4 -0.5 -0.3 -0.3 -0.3 -0.0 -0.6 -0.0 -0.8 0.2 -1.2 -0.4 -0.2 0.2 -0.6 -0.8 -0.8
Commuting to job workplace: Cycle 0.5 0.6 2.9 0.4 0.5 0.7 -0.1 0.1 -0.0 0.6 1.4 0.6 0.6 1.0 0.8 0.8 0.4 0.4 -0.8 0.0 0.6 0.7 1.1 0.6 1.3 0.7 0.7 0.3 0.4 1.0 1.5 0.3 0.4 0.1 -1.0 1.7 1.1
Myopia 0.8 1.1 3.7 0.5 0.2 0.2 0.4 1.5 1.5 1.0 -1.2 1.0 0.3 1.2 -0.8 0.8 0.9 1.9 -0.6 -0.3 -0.7 1.2 -1.5 -0.6 -1.7 1.8 -1.9 0.2 -0.1 0.2 0.4 1.6 0.5 0.0 -1.3 1.9 0.3
Vascular/heart problems diagnosed by doctor 0.3 0.7 12.6 0.3 3.5 -0.1 -0.8 0.4 0.2 0.4 0.7 0.4 0.7 -0.5 0.8 0.5 0.3 -0.3 0.8 -0.0 -1.0 0.1 -0.2 0.4 -0.4 -0.3 0.4 1.8 0.3 1.0 -0.7 -0.1 -0.4 0.9 0.9 -0.5 0.2
Cholesterol lowering medication 0.7 1.0 4.7 -1.1 -1.8 -0.6 -0.4 -1.0 0.1 -0.7 -2.2 -0.7 -0.6 -1.0 -1.7 -2.0 -1.6 -0.8 1.8 -0.2 0.6 -1.1 0.3 -0.5 -0.0 -1.0 0.0 -1.6 0.2 -0.4 -0.2 -0.7 0.5 -1.1 -0.4 -0.3 0.4
Medication: Omeprazole (e.g. Zanprol) 1.2 1.4 3.9 -1.3 0.5 -1.5 0.3 -1.6 -1.2 -1.4 -1.1 -1.4 -0.2 -1.3 -1.3 -1.0 -1.2 -1.6 1.7 -1.4 -2.0 -1.6 0.1 -0.7 0.1 -1.4 0.2 -1.6 -0.7 -0.7 -0.8 -1.4 -1.3 -1.6 -0.3 -1.1 -0.6
Pain experienced in last month 0.5 0.8 2.6 0.9 1.0 0.4 0.3 0.7 0.4 0.8 -0.7 0.8 1.3 1.2 1.6 1.2 1.1 0.8 -1.0 0.8 0.2 1.0 0.6 0.4 0.8 1.1 0.5 1.1 0.5 0.3 1.4 0.8 0.3 0.3 -0.0 1.6 1.2
Supplements: Calcium 0.7 0.7 2.8 0.5 -0.4 1.1 0.6 0.2 1.2 0.4 0.2 0.4 0.4 0.5 1.1 -0.1 0.0 0.0 -1.7 1.0 1.3 0.4 1.5 0.6 1.6 0.0 1.0 0.8 1.0 0.5 1.2 -0.1 1.0 0.5 1.2 0.6 1.2
Basal cell carcinoma (self-reported) 0.8 1.0 4.2 -0.7 0.6 -2.0 0.2 0.1 0.4 -0.4 -1.5 -0.3 -0.7 0.3 -1.1 1.0 -0.1 0.2 1.8 -1.6 -1.1 -0.9 -1.4 -1.6 -1.2 0.4 -1.4 0.2 -1.4 -0.2 -1.3 -0.5 -1.2 -0.6 -1.5 0.0 -0.3
Heart attack/myocardial infarction (self-reported) 1.0 1.3 3.6 1.5 -0.8 1.7 1.6 1.2 0.1 1.5 0.2 1.5 1.2 0.5 1.2 0.5 1.2 1.0 -0.6 1.6 1.9 1.4 0.4 1.2 0.2 0.8 0.7 0.7 1.5 1.8 0.6 1.2 1.5 0.7 0.7 0.7 0.9
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.9 -0.2 -0.6 -0.8 0.6 0.5 -0.1 -0.4 0.3 -0.4 -0.1 1.4 -0.7 1.0 0.4 0.6 0.0 -1.3 -0.2 -0.1 -1.3 -1.0 -1.0 0.8 -0.7 0.7 -0.7 0.3 0.2 0.4 -0.0 0.6 -0.6 0.3 1.4
Heart disease (siblings) 0.6 0.8 3.6 0.4 -1.7 1.3 -0.7 0.5 -0.2 1.1 -0.3 1.1 -1.0 0.8 0.2 -0.4 -0.4 1.0 -1.2 1.0 0.8 0.6 1.0 0.1 0.8 0.7 -0.0 -0.2 0.4 0.4 1.5 0.6 1.3 -0.0 -0.9 1.9 0.3
Alcohol drinker status: Previous 0.4 0.4 1.5 -0.6 -0.6 -0.6 0.3 -0.2 1.1 -0.1 -1.2 -0.1 -1.2 0.1 -0.9 -0.3 -0.9 -0.0 1.0 -0.4 -1.0 -0.5 -0.8 -1.2 -0.9 -0.3 -0.9 0.2 -0.4 0.2 -0.3 -0.6 -0.2 -0.3 -1.1 -0.3 0.2
Pack years of smoking 0.5 0.7 2.9 1.1 0.4 1.2 1.3 1.0 0.7 0.6 1.3 0.6 0.1 0.7 0.8 1.1 1.5 1.2 -0.6 -0.3 1.7 0.9 -0.7 0.2 -0.9 0.9 -0.7 0.5 0.1 0.2 -0.4 0.6 0.8 0.6 -0.1 0.1 0.3
Impedance of whole body 0.6 3.1 7.3 2.1 2.3 1.3 2.0 2.4 2.2 1.7 0.5 1.6 0.9 2.6 2.3 2.4 2.0 2.2 -1.8 0.2 1.4 2.2 -0.0 1.2 -0.0 2.4 -0.1 1.7 0.7 1.7 2.0 2.0 1.6 1.8 -0.7 2.7 1.1
Leg fat mass (left) 0.9 3.4 9.5 -1.8 -0.3 -1.7 -1.2 -1.9 -2.5 -2.0 -1.0 -2.0 -2.0 -1.6 -2.0 -1.4 -1.5 -1.8 2.2 -1.8 -1.4 -2.0 -1.5 -2.5 -1.6 -1.7 -1.7 -1.6 -1.7 -1.9 -2.9 -2.0 -1.7 -1.8 0.4 -3.1 -1.9
Arm predicted mass (left) 0.5 2.6 11.1 -1.3 0.4 -0.6 -1.4 -2.0 -2.8 -1.4 1.2 -1.4 0.1 -2.9 -0.8 -1.9 -1.1 -2.6 0.8 0.3 -0.8 -1.8 0.5 -0.5 0.5 -2.7 0.5 -0.7 -0.0 -1.4 -2.4 -2.2 -1.5 -1.3 1.8 -3.3 -1.6