Hub : Genes

CDC20B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Testicular Germ Cell Tumors 0.171 0.094 0.0031 0.003 0.017 0.001 NA 0.006 0.260 0.079 0.2800 NA 0.1800
2 TCGA Thyroid Carcinoma 0.042 0.027 0.0039 0.024 0.017 0.026 NA 0.026 0.002 0.008 0.0014 NA 0.0012

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.1 0.1 0.2 -0.2 0.4
Bipolar Disorder or Schizophrenia 0.2 0.5 1.0 0.4 -1.0
Depressed Affect (Nagel 2018) 0.4 0.8 0.8 0.8 -0.9
Depression (Nagel 2018) 3.9 5.9 6.4 2.3 -2.5
Intelligence (Savage-Jansen 2018) 0.4 1.2 1.5 -0.9 1.2
Neuroticism (Nagel 2018) 0.0 0.1 0.1 0.1 -0.3
Schizophrenia (2018) 0.8 1.7 2.5 0.9 -1.6
Schizophrenia vs Biploar Disorder 0.2 0.3 0.6 0.1 -0.8
Worry (Nagel 2018) 0.0 0.0 0.1 -0.2 0.1
Alzheimer’s Disease (in mother) 2.3 2.7 4.0 -1.2 2.0
Alzheimer’s Disease (in father) 0.9 0.9 1.9 -0.1 1.4
Alzheimer’s Disease (including proxy) 0.9 1.3 2.1 -0.8 1.4
Crohns Disease (2017) 0.1 0.3 0.3 0.5 0.6
Irritable Bowel Disease (IBD) 0.3 0.6 1.3 0.0 1.1
Ulcerative Colitis (UC) 0.2 0.4 0.7 -0.4 0.8
Major Depression (MDD) 0.1 0.1 0.2 -0.4 -0.1
Reaction Time 0.5 1.0 1.6 0.6 -1.3
Verbal and Numeric Reasoning (VNR) 0.0 0.1 0.1 -0.3 0.4
Breast Cancer 0.0 0.1 0.2 0.4 0.1
Ovarian Cancer 1.3 1.8 3.3 0.4 1.8
Prostate Cancer 0.0 0.0 0.0 -0.1 0.1
Age at First Birth 1.2 1.8 2.8 -0.9 -1.7
Bipolar Disorder (2011) 0.4 0.3 0.6 -0.8 0.3
Body Mass Index (BMI) (2010) 0.7 1.0 2.0 -1.4 0.2
Coronary Artery Disease (CAD) 0.4 0.4 0.8 -0.9 -0.2
Crohns Disease (2012) 0.3 0.5 0.8 0.9 0.4
Mean Putamen Volume 2.1 2.4 2.9 -1.7 1.4
Fasting Glucose 0.1 0.1 0.2 0.2 -0.4
HbA1C 0.1 0.1 0.1 -0.1 -0.4
HDL Cholesterol 0.2 0.4 0.7 -0.9 0.1
LDL Cholesterol 0.2 0.3 0.5 -0.7 0.1
Lupus 0.5 0.8 1.5 -0.3 -1.2
Neuroticism (2016) 0.0 0.1 0.1 -0.1 0.3
Primary Biliary Cirrhosis 0.8 1.2 1.4 1.2 -1.0
Rheumatoid Arthritis 0.1 0.1 0.3 -0.5 -0.1
Schizophrenia (2014) 0.2 0.5 0.8 0.5 -0.9
Triglycerides 0.0 0.0 0.1 -0.3 -0.0
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.2 -0.4 -0.5
Ulcerative Colitis 0.1 0.1 0.2 0.0 0.5
Blood Eosinophil Count 1.4 10.8 14.0 3.7 -2.8
Blood Platelet Count 0.0 0.5 0.9 -1.0 -0.1
Blood Red Count 0.1 0.8 1.1 -0.7 -1.1
Blood White Count 0.2 1.2 1.6 -1.3 0.9
Heel T-Score 4.8 38.1 49.1 5.2 -7.0
BMI 0.6 3.4 4.3 -2.1 1.6
Height 0.6 11.1 20.9 -1.1 -4.6
Waist Hip Ratio (WHR) 0.3 1.5 1.9 -1.4 1.0
Systolic Blood Pressure 0.1 0.4 0.7 -0.8 -0.5
Smoking Status 0.1 0.2 0.4 0.6 -0.2
Allergy or Eczema 0.4 1.1 2.1 0.4 -1.4
Cardiovascular Disease 0.1 0.4 0.6 -0.7 0.5
Hypothyroidism (self reported) 1.9 4.3 7.5 -1.0 2.7
Respiratory disease 0.4 0.8 1.6 -1.3 -0.1
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.4 -0.6 -0.2
Lung FEV1/FVC ratio 1.8 9.2 17.8 4.2 -0.8
Lung FVC 1.7 8.9 11.8 3.4 -2.5
Neuroticism 0.4 1.1 1.3 -1.1 0.9
Chronotype (morning person) 0.4 0.8 1.6 -0.0 1.3
Hair Pigment 0.0 0.9 0.9 -1.0 0.9
Tanning 0.0 0.3 0.5 0.4 -0.7
Hand grip strength (left) 0.5 1.4 2.8 -0.1 -1.7
Number of treatments/medications taken 0.8 1.4 1.8 -1.4 0.9
Average weekly spirits intake 0.7 0.9 1.4 -0.7 1.2
Sensitivity / hurt feelings 1.2 2.0 3.8 -0.4 2.0
Frequency of depressed mood in last 2 weeks 0.6 0.8 1.1 1.1 -0.7
Hearing difficulty/problems: Yes 0.8 1.3 2.4 1.6 0.3
Relative age of first facial hair 0.2 0.5 1.0 -0.1 1.0
Other serious medical condition/disability diagnosed by doctor 1.6 2.1 3.5 -0.9 1.9
Ever used hormone-replacement therapy (HRT) 0.7 1.0 1.9 -1.4 -0.0
Ever had hysterectomy (womb removed) 0.7 0.8 1.4 -0.5 1.2
Systolic blood pressure, automated reading 0.5 1.5 1.7 -1.2 1.3
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.1 -0.3 -0.3
Angina 0.4 0.5 1.0 1.0 0.3
Medication for hormone replacement therapy 0.2 0.2 0.2 0.4 0.5
Vitamin and mineral supplements 0.5 0.7 0.7 0.8 -0.8
Supplements: Zinc 1.0 1.1 1.4 -0.8 1.2
Medication: Co-codamol 0.3 0.4 0.7 0.3 0.8
Medication: Metformin 0.0 0.0 0.0 0.2 -0.2
Diabetes (father) 1.2 1.5 2.9 -0.5 1.7
Diabetes (mother) 0.5 0.6 0.8 0.7 -0.9
Severe depression (siblings) 0.2 0.2 0.2 -0.5 0.4
Pack years adult smoking proportion 2.1 3.2 3.5 -1.7 1.9
Impedance of leg (right) 0.3 1.5 2.7 1.6 -0.5
Leg fat-free mass (left) 0.6 3.0 5.6 -2.4 -0.6
Trunk fat percentage 0.9 3.5 4.3 -2.1 1.6
Hand grip strength (right) 0.4 1.0 1.9 0.4 -1.4
Townsend deprivation index at recruitment 0.2 0.3 0.4 -0.5 0.7
Current tobacco smoking 1.4 2.2 2.6 -1.3 1.6
Average weekly fortified wine intake 0.2 0.2 0.3 -0.5 -0.4
Maternal smoking around birth 0.2 0.2 0.4 0.1 -0.7
Fed-up feelings 0.0 0.1 0.2 -0.2 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.2 2.7 1.3 -1.7
Relative age voice broke 0.8 1.3 2.1 1.4 -0.7
Taking other prescription medications 1.1 1.6 2.0 -1.4 1.1
Age when periods started (menarche) 0.2 0.5 1.0 -1.0 0.1
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 1.8 -1.2 1.3
Heel bone mineral density (BMD) T-score, automated (left) 3.0 6.7 11.0 1.6 -3.3
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 1.4 1.2 0.2
Qualifications: CSEs or equivalent 3.1 4.0 5.9 2.4 -1.5
Serious illness, injury or assault to yourself 1.0 1.2 2.2 -0.5 1.5
High blood pressure 0.5 1.3 1.4 -1.1 1.2
Hayfever, allergic rhinitis or eczema 0.3 0.8 1.2 0.6 -1.1
Multivitamins +/- minerals 1.6 2.0 2.4 -1.6 1.2
Stomach or abdominal pain in last month 0.4 0.5 0.6 -0.8 0.6
Supplements: Glucosamine 0.4 0.6 0.7 -0.7 0.9
Diverticular disease/diverticulitis (self-reported) 3.9 4.6 6.2 -1.8 2.5
Medication: Atenolol 2.3 2.9 5.2 -0.8 2.3
Medication: Levothyroxine sodium 2.6 4.3 5.5 -1.8 2.3
Sitting height 0.5 3.5 4.2 -2.1 -1.6
Chronic bronchitis/emphysema (father) 0.5 0.5 0.5 -0.7 0.7
High blood pressure (mother) 2.1 2.9 4.6 2.2 -1.1
Body mass index (BMI) 0.7 2.8 3.7 -1.9 1.4
Impedance of leg (left) 0.2 1.1 2.1 1.4 -0.2
Leg predicted mass (left) 0.6 3.1 5.9 -2.4 -0.5
Trunk fat mass 1.0 4.2 6.7 -2.6 1.4
Waist circumference 0.6 2.2 3.1 -1.8 1.2
Number of incorrect matches in round 0.2 0.3 0.4 0.6 0.4
Past tobacco smoking 0.0 0.0 0.0 -0.1 -0.0
Alcohol usually taken with meals 0.5 0.7 1.2 -0.5 1.1
Nervous feelings 0.1 0.1 0.2 0.5 0.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.4 0.1 -0.7
Hearing difficulty/problems with background noise 0.4 0.6 1.1 1.1 -0.1
Hair/balding pattern: Pattern 2 1.9 2.5 3.8 -1.1 -2.0
Had menopause 4.7 5.9 8.9 -3.0 1.7
Had other major operations 0.9 1.1 1.7 -0.7 1.3
Forced vital capacity (FVC) 1.5 5.8 10.6 1.0 -3.3
Heel bone mineral density (BMD) T-score, automated (right) 4.3 9.8 14.0 2.3 -3.7
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.1 -0.3 0.3
Qualifications: None of the above 0.3 0.6 0.7 0.7 0.8
Financial difficulties in last 2 years 0.7 1.0 1.3 0.8 1.1
Mouth/teeth dental problems 0.8 1.2 1.9 -1.4 -0.7
Heart attack 0.3 0.4 0.7 0.2 0.8
Allergy 0.3 0.7 1.1 -0.5 1.0
Pain all over the body in last month 0.4 0.4 0.5 0.5 -0.7
Diabetes (self-reported) 0.0 0.0 0.0 0.0 -0.0
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.8 0.2 0.9
Medication: Ramipril 0.1 0.2 0.2 -0.4 0.3
Medication: Simvastatin 0.6 0.9 1.7 -0.3 1.3
Fluid intelligence score 0.6 1.3 2.2 -1.5 0.6
Illnesses of siblings 0.5 0.8 1.5 0.0 1.2
Neuroticism score 0.2 0.5 0.8 -0.4 0.9
Weight 0.6 3.1 6.2 -2.5 0.2
Impedance of arm (right) 0.2 0.8 1.2 1.1 -0.6
Arm fat percentage (right) 0.9 3.4 3.9 -2.0 1.7
Trunk fat-free mass 0.7 3.8 7.2 -2.7 -0.6
Hip circumference 0.3 1.2 2.4 -1.5 -0.3
Time employed in main current job 0.1 0.1 0.1 -0.0 -0.4
Alcohol intake versus 10 years previously 0.1 0.1 0.2 0.5 0.2
Father’s age at death 1.2 1.6 2.5 0.8 -1.6
Worrier / anxious feelings 0.2 0.4 0.7 0.0 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.0 0.1 0.1 -0.2 0.3
Falls in the last year 1.2 1.6 1.6 -1.3 1.2
Hair/balding pattern: Pattern 3 0.1 0.2 0.4 0.6 0.1
Number of live births 0.3 0.4 0.6 0.5 -0.8
Forced expiratory volume in 1-second (FEV1) 3.1 10.4 13.7 2.7 -3.7
Pulse rate 0.1 0.2 0.2 0.5 0.4
Happiness 0.3 0.3 0.4 0.4 -0.7
Noisy workplace 0.1 0.1 0.2 0.4 -0.4
Qualifications: A levels/AS levels or equivalent 0.2 0.4 0.7 -0.8 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 0.9 -0.9 0.5
Mouth/teeth dental problems: Dentures 0.1 0.1 0.2 0.3 0.4
Asthma 0.1 0.1 0.1 -0.4 0.3
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.2 1.9 -1.4 0.6
Medication: Cholesterol lowering 0.4 0.6 1.3 -0.1 1.1
Depression (self-reported) 0.3 0.3 0.4 0.6 0.5
Medication: Lansoprazole 1.8 2.1 2.3 -1.5 1.4
Prospective memory result 0.3 0.4 0.7 0.8 -0.4
Lung cancer (father) 0.2 0.2 0.4 -0.6 -0.3
Illnesses of mother 0.0 0.0 0.1 0.1 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 2.1 6.7 9.5 2.0 -3.1
Pulse wave Arterial Stiffness index 1.3 1.5 2.7 -0.6 1.7
Impedance of arm (left) 0.2 1.1 1.2 1.1 -1.0
Arm fat mass (right) 0.9 3.6 5.8 -2.4 1.2
Trunk predicted mass 0.7 3.9 7.7 -2.8 -0.4
Standing height 0.5 4.7 5.9 -1.9 -2.4
Length of working week for main job 0.5 0.6 0.7 -0.7 0.8
Exposure to tobacco smoke at home 0.6 0.7 0.8 0.7 -0.9
Breastfed as a baby 0.1 0.1 0.1 0.3 0.3
Tense / ‘highly strung’ 0.4 0.6 1.0 0.4 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.3 2.8 -1.7 1.4
Hair/balding pattern: Pattern 4 0.4 0.9 1.6 0.3 1.3
Birth weight of first child 1.1 2.1 4.0 0.4 -2.0
Peak expiratory flow (PEF) 0.5 1.2 1.3 1.0 -1.2
Pulse wave reflection index 0.3 0.4 0.4 -0.7 0.5
Ever highly irritable/argumentative for 2 days 0.9 1.1 1.9 -0.5 1.4
Loud music exposure frequency 1.6 1.8 2.0 -1.4 1.2
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.6 0.1 -0.7
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 0.6 0.6 -0.7
Blood clot in the leg (DVT) 0.4 0.5 1.0 0.2 -1.0
Medication: Paracetamol 0.6 1.0 1.1 -1.0 1.0
Headache pain in last month 0.0 0.1 0.2 0.4 -0.1
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 1.7 0.5 -1.3
Glaucoma (self-reported) 0.6 0.7 0.8 0.7 -0.9
Gout (self-reported) 0.2 0.2 0.5 -0.7 -0.1
Hypothyroidism/myxoedema (self-reported) 3.2 6.3 9.1 -1.9 3.0
Medication: Amlodipine 0.1 0.1 0.1 0.0 0.4
Medication: Ventolin 100micrograms inhaler 1.1 1.4 2.3 -0.7 1.5
Birth weight 0.6 1.3 2.2 0.7 -1.5
Chronic bronchitis/emphysema (mother) 0.4 0.5 0.8 -0.9 0.3
High blood pressure (siblings) 1.0 1.4 2.6 0.4 -1.6
Forced vital capacity (FVC), Best measure 1.0 3.7 6.6 0.9 -2.6
Body fat percentage 0.8 3.0 3.1 -1.7 1.8
Leg fat percentage (right) 0.8 3.0 3.7 -1.5 1.9
Arm fat-free mass (right) 0.8 4.2 8.5 -2.9 -0.0
Exposure to tobacco smoke outside home 2.1 2.8 3.1 -1.8 1.6
Comparative body size at age 10 0.3 0.7 1.4 -1.2 0.2
Number of full brothers 2.0 2.6 3.4 1.9 -1.3
Worry too long after embarrassment 0.3 0.4 0.7 -0.3 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.2 0.2 -0.4 0.4
Wheeze or whistling in the chest in last year 0.1 0.2 0.4 -0.3 -0.6
Number of children fathered 0.9 1.0 1.0 1.0 1.0
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 2.2 -1.0 1.5
Age at first live birth 1.8 3.2 4.5 1.4 -2.1
Pulse wave peak to peak time 1.4 1.7 3.1 0.5 -1.8
Health satisfaction 0.4 0.5 0.9 -0.5 0.9
Shortness of breath walking on level ground 1.6 1.9 3.4 -0.7 1.8
Qualifications: College or University degree 0.6 1.8 3.5 -0.3 -1.9
Eye problems/disorders: None of the above 0.0 0.0 0.0 0.1 -0.0
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.0 0.4 1.0
Emphysema/chronic bronchitis 2.1 2.3 2.4 -1.5 1.6
Medication for pain relief, constipation, heartburn 1.2 2.0 2.5 1.2 -1.6
Neck or shoulder pain in last month 0.0 0.1 0.1 0.0 -0.3
Medication: Blood pressure 0.3 0.5 1.0 -0.1 1.0
Angina (self-reported) 0.6 0.7 1.1 1.1 0.6
Migraine (self-reported) 0.1 0.1 0.2 -0.4 0.2
Medication: Ibuprofen 0.4 0.4 0.6 -0.8 0.5
Medication: Allopurinol 0.5 0.6 1.1 -0.4 1.0
Medication: Omeprazole 0.1 0.1 0.2 -0.2 0.4
Medication: Seretide 50 evohaler 0.5 0.6 0.7 0.6 0.9
Mean time to correctly identify matches 0.0 0.1 0.1 0.1 -0.4
Heart disease (mother) 0.8 1.0 1.8 -1.3 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.5 0.1 -0.7
Whole body fat mass 0.9 3.7 5.3 -2.3 1.4
Leg fat mass (right) 0.9 3.3 4.3 -2.1 1.5
Arm predicted mass (right) 0.7 3.8 7.6 -2.8 0.0
Pulse rate, automated reading 0.3 0.8 0.9 -0.9 0.9
Alcohol intake frequency. 0.4 1.0 1.6 -0.6 1.3
Comparative height size at age 10 0.4 2.3 4.2 -2.1 -0.5
Number of full sisters 0.4 0.4 0.6 0.8 -0.5
Suffer from ‘nerves’ 1.3 2.0 3.4 -0.8 1.8
Overall health rating 0.9 2.0 2.8 -1.1 1.7
Chest pain or discomfort 0.5 0.7 1.2 -1.1 0.5
Had major operations 0.0 0.0 0.0 0.1 -0.2
Age at last live birth 2.2 3.2 3.7 1.7 -1.9
Family relationship satisfaction 1.1 1.4 2.7 -1.7 0.1
Leg pain on walking 1.6 2.0 2.3 -1.5 1.3
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.1 1.1 0.2
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.3 0.0 0.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 0.7 0.0 -0.8
Medication: Aspirin 1.9 2.6 4.7 -0.7 2.2
Supplements: Vitamin C 0.4 0.5 1.0 0.1 1.0
Knee pain experienced in last month 0.7 1.1 1.2 -1.0 1.1
Hypertension (Self-reported) 0.4 1.2 1.6 -0.9 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.8 2.1 4.1 -2.0 0.4
Illnesses of father: Heart disease 1.1 1.5 1.5 -1.2 1.2
Illnesses of siblings: Diabetes 0.3 0.4 0.6 -0.5 -0.8
Smoking status: Previous 0.4 0.5 0.6 0.8 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.7 3.3 1.4 -1.8
Whole body fat-free mass 0.6 3.7 7.0 -2.6 -0.6
Leg fat-free mass (right) 0.6 3.0 5.5 -2.4 -0.7
Arm fat percentage (left) 1.0 4.1 4.9 -2.2 1.8
Average weekly red wine intake 0.2 0.3 0.4 0.4 -0.6
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.4 -0.6 -0.3
Mood swings 0.5 1.0 1.5 0.7 -1.2
Loneliness, isolation 0.2 0.3 0.6 0.2 0.8
Long-standing illness, disability or infirmity 2.4 3.7 6.4 -1.0 2.5
Ever had bowel cancer screening 1.5 1.8 2.8 -0.9 1.7
Diabetes diagnosed by doctor 0.1 0.2 0.2 -0.3 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.8 1.7 1.3 -0.1
Friendships satisfaction 0.6 0.8 1.3 -1.1 0.5
Qualifications: nursing, teaching 0.2 0.3 0.5 0.0 -0.7
Commuting to job workplace: Walk 0.2 0.2 0.5 -0.1 -0.7
Eye problems/disorders: Cataract 0.0 0.0 0.1 -0.2 0.1
Mouth/teeth dental problems: Mouth ulcers 0.8 1.2 2.5 1.6 0.0
Medication for cholesterol 0.1 0.1 0.1 -0.3 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.3 0.6 0.3
Back pain experienced in last month 1.3 1.9 3.2 -0.8 1.8
Mineral and other dietary supplements 0.1 0.1 0.1 0.2 -0.4
Breast cancer (self-reported) 0.6 0.7 1.0 -1.0 0.5
Asthma (self-reported) 0.1 0.1 0.3 -0.5 -0.2
Osteoporosis (self-reported) 0.2 0.2 0.5 0.2 0.7
Osteoarthritis (self-reported) 1.5 2.0 2.2 -1.5 1.3
Medication: Aspirin 2.4 3.2 6.1 -0.5 2.5
Medication: Gliclazide 0.0 0.1 0.1 -0.3 0.1
Illnesses of father: None of the above (group 1) 0.5 0.7 1.3 -0.1 -1.2
Smoking status: Current 1.4 2.2 2.4 -1.6 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.7 3.7 4.7 2.2 -1.6
Whole body water mass 0.6 3.6 6.9 -2.6 -0.5
Leg predicted mass (right) 0.5 2.9 5.3 -2.3 -0.7
Arm fat mass (left) 1.0 4.3 7.0 -2.6 1.3
Number of self-reported non-cancer illnesses 0.3 0.5 1.0 -0.1 1.0
Average weekly champagne plus white wine intake 0.7 1.0 1.5 0.7 -1.2
Miserableness 2.9 5.1 5.7 2.4 -2.1
Guilty feelings 0.2 0.3 0.6 -0.8 0.3
Wears glasses or contact lenses 3.1 3.6 4.5 -2.1 1.6
Ever taken oral contraceptive pill 5.0 5.6 6.6 2.1 -2.6
Hearing aid user 0.2 0.3 0.5 0.2 -0.7
Mother’s age at death 0.4 0.4 0.6 -0.8 0.5
Financial situation satisfaction 0.0 0.0 0.0 -0.1 0.2
Tinnitus: Yes, now most or all of the time 1.8 2.1 2.5 -1.3 1.6
Commuting to job workplace: Public transport 0.2 0.2 0.4 -0.6 0.1
Eye problems/disorders: Glaucoma 1.4 1.7 2.2 1.1 -1.5
Medication: Blood pressure 1.4 2.7 4.8 -0.8 2.2
Pain type(s) experienced in last month: Hip pain 5.6 7.0 9.8 -2.1 3.1
Supplements: Fish oil (including cod liver oil) 0.8 1.1 1.6 -1.2 0.8
High cholesterol (Self-reported) 0.8 1.4 1.7 -1.1 1.3
Medication: Bendroflumethiazide 1.4 2.1 2.7 -1.2 1.6
Medication: Paracetamol 0.8 1.3 1.4 -1.0 1.2
Medication: Lisinopril 0.4 0.5 0.5 0.7 0.7
Medication: Atorvastatin 1.8 2.3 3.0 -1.2 1.7
Illnesses of father: High blood pressure 0.3 0.3 0.5 0.4 0.7
Alcohol drinker status: Never 0.3 0.4 0.6 0.4 -0.8
Ever smoked 0.3 0.5 1.1 -1.0 0.1
Basal metabolic rate 0.6 3.4 6.6 -2.6 -0.5
Leg fat percentage (left) 1.0 3.5 4.4 -1.6 2.1
Arm fat-free mass (left) 0.8 4.1 8.1 -2.8 -0.2
Number of operations (self-reported) 0.3 0.4 0.5 -0.6 0.7
Average weekly beer plus cider intake 0.6 0.8 0.9 -0.9 0.9
Irritability 0.2 0.4 0.5 -0.5 0.7
Risk taking 0.5 0.7 1.3 -0.3 1.1
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.4 0.6 -0.2
Fractured/broken bones in last 5 years 0.8 1.0 1.7 1.3 0.6
Age started oral contraceptive pill 1.9 2.4 3.2 -1.2 1.8
Diastolic blood pressure, automated reading 2.3 7.0 8.4 -2.9 2.4
Ever depressed for a whole week 0.2 0.3 0.6 -0.2 0.8
Unable to work because of sickness or disability 0.4 0.5 0.7 0.8 -0.5
Commuting to job workplace: Cycle 0.4 0.5 0.9 0.3 -0.9
Myopia 0.2 0.2 0.3 -0.4 0.6
Vascular/heart problems diagnosed by doctor 0.6 1.7 2.6 0.9 -1.6
Cholesterol lowering medication 0.1 0.2 0.3 -0.5 0.3
Medication: Omeprazole (e.g. Zanprol) 0.2 0.2 0.5 -0.7 0.1
Pain experienced in last month 0.1 0.1 0.1 -0.2 -0.4
Supplements: Calcium 0.1 0.1 0.3 -0.5 0.0
Basal cell carcinoma (self-reported) 0.7 0.9 1.0 -0.8 1.0
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.8 -0.0 0.9
Deep venous thrombosis (DVT) (self-reported) 0.5 0.7 1.4 0.2 -1.2
Heart disease (siblings) 0.1 0.1 0.1 -0.4 -0.3
Alcohol drinker status: Previous 0.1 0.1 0.1 -0.2 0.3
Pack years of smoking 2.1 3.1 3.8 -1.5 1.9
Impedance of whole body 0.3 1.7 2.5 1.6 -0.9
Leg fat mass (left) 1.0 3.7 4.8 -2.2 1.6
Arm predicted mass (left) 0.7 3.3 6.6 -2.6 -0.4