TWAS hub - CDC20P1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.154	0.0440	3.9e-04	0.098	NA	0.049	NA	0.075	2.2e-08	NA	7.1e-05	NA	1.1e-06
2	GTEx	Artery Aorta	0.234	0.0610	6.6e-05	0.164	NA	0.188	NA	0.170	2.3e-09	NA	1.3e-10	NA	1.2e-09
3	GTEx	Brain Caudate basal ganglia	0.535	0.0890	2.9e-06	0.084	NA	0.328	NA	0.361	2.1e-03	NA	3.5e-10	NA	2.9e-11
4	GTEx	Brain Cerebellar Hemisphere	0.476	0.0910	2.4e-05	0.421	NA	0.366	NA	0.399	4.9e-12	NA	2.6e-10	NA	2.5e-11
5	GTEx	Brain Cerebellum	0.647	0.0710	4.0e-09	0.390	NA	0.359	NA	0.420	1.4e-12	NA	1.7e-11	NA	1.1e-13
6	GTEx	Brain Nucleus accumbens basal ganglia	0.419	0.1070	1.9e-03	0.005	NA	0.041	NA	0.065	2.3e-01	NA	2.9e-02	NA	7.9e-03
7	GTEx	Heart Atrial Appendage	0.228	0.0800	2.8e-03	0.100	NA	0.073	NA	0.066	3.2e-05	NA	3.6e-04	NA	6.5e-04
8	GTEx	Muscle Skeletal	0.131	0.0463	1.6e-03	0.062	NA	0.027	NA	0.035	1.1e-06	NA	1.1e-03	NA	2.1e-04
9	GTEx	Pancreas	0.262	0.0710	3.9e-04	0.153	NA	0.147	NA	0.163	5.3e-07	NA	9.4e-07	NA	2.2e-07
10	GTEx	Skin Not Sun Exposed Suprapubic	0.368	0.0580	8.0e-11	0.374	NA	0.345	NA	0.355	1.3e-21	NA	1.1e-19	NA	2.5e-20
11	GTEx	Skin Sun Exposed Lower leg	0.413	0.0490	0.0e+00	0.392	NA	0.393	NA	0.402	2.1e-34	NA	1.6e-34	NA	2.0e-35
12	GTEx	Thyroid	0.081	0.0350	7.1e-03	0.047	NA	0.023	NA	0.025	1.6e-04	NA	6.9e-03	NA	4.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
HbA1C	8.6	9.5	12.3	-3.2	-2.7	-2.7	-3.3	-3.5	-2.1	-2.9	-3.2	-3.3	-3.5	-3.3	-3.0
Myopia	4.8	6.9	9.4	2.9	2.8	2.5	2.5	2.7	2.0	1.9	2.7	2.8	2.7	2.8	3.1
Commuting to job workplace: Walk	4.5	4.9	8.0	2.0	2.0	2.5	2.3	2.8	1.7	2.1	1.8	2.3	2.5	2.4	1.6
Medication: Lansoprazole	4.3	4.9	7.8	1.7	2.2	2.7	2.3	2.4	1.3	2.8	1.9	2.4	2.5	2.3	1.6
Number of full sisters	4.0	4.8	8.2	-2.2	-2.3	-1.2	-2.8	-2.6	-1.1	-1.8	-1.8	-2.9	-2.6	-2.6	-1.7
Medication: Lisinopril	3.8	4.9	9.7	2.5	3.1	0.6	1.7	2.1	0.5	2.2	2.9	2.2	2.1	2.3	2.7
Age started oral contraceptive pill	3.7	4.7	6.6	2.3	2.5	2.1	2.1	2.2	1.3	1.9	2.0	2.3	2.5	2.6	1.9
Average weekly red wine intake	3.3	4.8	6.7	-2.0	-2.2	-1.7	-2.5	-2.5	-1.7	-1.9	-2.0	-2.6	-2.5	-2.5	-2.0
Qualifications: None of the above	3.2	6.9	10.5	-3.1	-2.3	-1.6	-3.1	-2.9	-1.8	-2.7	-2.7	-2.5	-2.4	-2.7	-3.2
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	5.7	1.8	2.1	1.3	2.3	2.4	1.3	1.8	1.6	2.1	2.1	2.1	1.8
Smoking status: Current	2.8	4.4	8.0	-2.4	-1.7	-2.4	-2.1	-1.8	-1.8	-1.2	-2.7	-1.8	-1.9	-2.1	-2.8
Osteoporosis (self-reported)	2.5	3.1	6.6	1.9	1.7	0.7	1.8	2.3	-0.2	1.8	2.6	1.5	1.7	1.9	1.8
Irritability	2.5	4.2	9.0	1.9	1.9	0.6	2.7	2.4	0.3	3.0	1.4	2.3	2.4	2.3	1.5
Chronic bronchitis/emphysema (mother)	2.4	2.8	4.7	-1.8	-2.1	-0.5	-1.6	-2.1	-1.0	-2.2	-1.5	-1.7	-1.6	-1.7	-1.4
Breast Cancer	2.3	5.5	8.4	2.6	2.7	1.3	2.2	2.8	1.2	2.2	2.8	2.1	2.2	2.4	2.9
Current tobacco smoking	2.3	3.8	7.0	-2.2	-1.4	-2.5	-1.9	-1.6	-1.8	-1.0	-2.5	-1.5	-1.7	-1.9	-2.6
Average weekly spirits intake	2.2	2.7	4.4	-1.4	-1.6	-1.1	-2.0	-2.1	-0.7	-1.8	-1.3	-1.9	-2.0	-1.9	-1.2
Average weekly fortified wine intake	2.2	2.5	4.0	1.8	1.3	1.2	2.0	1.9	0.4	1.3	1.6	1.8	1.8	1.9	1.4
Medication: Ibuprofen	2.2	2.6	4.3	1.3	1.8	1.0	2.1	2.1	1.4	1.3	1.2	1.9	1.8	1.8	1.3
Neuroticism score	2.0	4.1	6.3	2.0	1.8	1.5	2.3	2.3	1.1	2.5	1.8	2.3	2.3	2.3	1.8
Worrier / anxious feelings	2.0	3.8	5.9	1.9	1.5	1.4	2.1	2.3	0.8	2.0	1.8	2.4	2.4	2.4	1.6
Medication: Aspirin	2.0	2.7	5.3	-1.9	-1.8	-1.2	-1.3	-1.7	-1.0	-1.7	-2.0	-1.3	-1.3	-1.5	-2.3
Worry too long after embarrassment	1.9	3.3	5.4	1.6	1.4	2.3	1.7	2.2	2.1	1.9	1.4	1.7	1.9	1.8	1.2
Suffer from ‘nerves’	1.9	3.0	5.5	1.9	1.6	1.4	1.8	1.7	1.2	1.5	1.9	1.8	1.7	1.9	2.3
Supplements: Glucosamine	1.8	2.4	6.5	-1.5	-2.5	-0.5	-1.4	-1.6	0.0	-2.0	-1.4	-1.7	-1.5	-1.5	-1.3
Mouth/teeth dental problems	1.8	2.8	5.0	1.2	1.3	1.7	2.1	1.7	0.5	1.7	1.2	2.2	2.2	2.0	1.1
Mouth/teeth dental problems: Dentures	1.8	3.1	5.9	-1.3	-1.5	-2.4	-1.8	-1.4	-1.9	-2.4	-1.1	-1.8	-1.9	-1.7	-1.2
Time employed in main current job	1.7	1.9	3.6	-1.8	-1.7	-0.5	-1.3	-1.3	0.1	-1.2	-1.8	-1.3	-1.2	-1.4	-1.9
Medication: Seretide 50 evohaler	1.7	2.0	3.3	1.6	1.4	0.7	1.2	1.7	0.5	1.8	1.7	1.3	1.4	1.6	1.4
Medication for hormone replacement therapy	1.6	1.8	8.4	0.1	-0.3	2.9	0.9	0.3	2.7	1.2	-0.1	1.0	1.3	0.9	0.0
Standing height	1.6	15.4	48.7	-3.8	-4.6	-3.9	-3.2	-2.6	-2.8	-7.0	-3.5	-3.2	-3.4	-3.4	-3.9
Commuting to job workplace: Car/motor vehicle	1.6	1.8	2.8	-1.6	-1.4	-1.0	-1.4	-1.7	-0.4	-1.2	-1.4	-1.5	-1.4	-1.6	-1.0
Ever used hormone-replacement therapy (HRT)	1.5	1.9	3.0	1.1	1.1	1.6	1.4	1.5	1.4	1.6	1.0	1.6	1.7	1.6	0.9
Townsend deprivation index at recruitment	1.5	2.2	4.2	-1.7	-1.9	-0.8	-1.4	-1.5	0.0	-1.1	-2.0	-1.2	-1.2	-1.5	-2.0
Chronic bronchitis/emphysema (father)	1.5	1.7	2.8	-1.4	-1.5	-0.3	-1.6	-1.7	-0.2	-1.3	-1.3	-1.3	-1.3	-1.4	-1.3
Hair/balding pattern: Pattern 4	1.5	3.7	5.8	-1.9	-1.0	-2.4	-2.2	-2.2	-2.3	-1.0	-1.2	-2.3	-2.3	-2.2	-1.1
Mean Putamen Volume	1.4	1.6	3.9	-1.2	-2.0	-0.7	-1.0	-1.5	0.1	-1.1	-1.4	-1.1	-1.0	-1.2	-1.7
Neuroticism	1.4	3.3	5.2	1.8	1.7	1.6	1.9	2.0	1.4	2.3	1.7	1.9	2.0	1.9	1.6
Hair/balding pattern: Pattern 2	1.4	1.8	4.7	-1.1	-0.5	-2.2	-1.3	-1.2	-2.2	-0.9	-1.0	-1.2	-1.4	-1.2	-1.1
Illnesses of siblings: Diabetes	1.4	1.7	4.4	-1.0	-0.0	-1.6	-2.1	-1.2	-0.8	-1.1	-0.7	-1.6	-1.8	-1.6	-0.7
Bipolar Disorder (2011)	1.3	1.3	3.5	-1.6	-1.4	-0.7	-0.5	-0.5	-0.3	-1.3	-1.9	-0.4	-0.4	-1.0	-1.9
Stomach or abdominal pain in last month	1.3	1.6	3.5	-1.7	-1.5	-1.4	-0.7	-1.1	-1.2	-0.9	-1.8	-0.7	-0.7	-0.9	-1.9
High blood pressure (mother)	1.3	1.8	4.3	1.1	0.7	2.1	1.5	1.2	1.6	1.1	1.0	1.4	1.4	1.4	0.9
Breastfed as a baby	1.3	1.6	2.7	1.4	1.1	1.0	1.4	1.6	0.7	1.2	1.6	0.8	1.1	1.3	1.6
Chest pain or discomfort	1.3	1.9	3.6	1.4	1.8	0.8	1.5	1.2	0.2	1.9	1.5	1.1	1.2	1.3	1.7
Medication: Aspirin	1.3	1.7	3.4	-1.5	-1.5	-1.0	-0.9	-1.3	-0.8	-1.4	-1.6	-1.0	-1.0	-1.1	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	8.2	-1.9	-1.7	-1.3	-1.0	-0.8	-1.0	-2.9	-1.9	-1.0	-1.2	-1.4	-2.0
Basal cell carcinoma (self-reported)	1.3	1.5	3.2	-1.6	-1.2	0.3	-1.3	-1.8	0.5	-1.6	-0.9	-1.3	-1.3	-1.4	-0.8
Sensitivity / hurt feelings	1.2	2.1	3.6	1.3	1.5	0.8	1.5	1.7	0.9	1.9	1.2	1.6	1.6	1.6	1.2
Exposure to tobacco smoke outside home	1.2	1.5	2.2	1.3	1.0	1.3	1.1	1.2	1.2	1.5	1.2	1.2	1.3	1.3	1.2
Leg pain on walking	1.2	1.5	5.0	-0.9	-0.6	-2.2	-1.1	-1.1	-1.3	-0.9	-0.7	-1.5	-1.5	-1.4	-0.6
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.7	0.9	1.2	0.3	1.9	1.6	0.7	1.2	0.6	1.5	1.5	1.4	0.7
Alcohol drinker status: Never	1.2	1.4	5.6	0.8	1.0	-2.4	-0.4	0.5	-2.2	-0.4	1.4	-0.6	-0.6	-0.1	1.2
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	2.2	-1.5	-1.4	-1.0	-1.2	-1.2	-0.7	-0.8	-1.5	-1.0	-1.0	-1.2	-1.2
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	3.5	-1.6	-1.0	-1.3	-1.3	-1.1	-1.2	-1.1	-1.8	-1.1	-1.1	-1.3	-1.9
Neuroticism (Nagel 2018)	1.0	2.4	4.2	1.6	1.4	1.3	1.4	1.7	1.2	2.0	1.6	1.5	1.6	1.7	1.4
Worry (Nagel 2018)	1.0	2.1	4.5	1.7	1.6	0.5	1.2	1.5	0.2	1.5	2.1	1.2	1.3	1.5	1.9
Height	1.0	19.2	71.4	-3.6	-5.3	-4.9	-3.5	-2.5	-3.8	-8.4	-3.2	-3.2	-3.6	-3.4	-4.1
High blood pressure	1.0	2.7	6.2	1.2	1.0	2.5	1.5	1.3	2.4	1.1	1.1	2.0	1.9	1.8	1.1
Had menopause	1.0	1.3	2.6	1.4	1.2	1.1	0.8	1.0	0.6	1.0	1.6	0.9	1.2	1.3	1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	5.0	-1.6	-2.1	0.3	-1.6	-1.6	-0.2	-1.4	-2.2	-1.3	-1.1	-1.5	-1.9
Number of full brothers	1.0	1.3	2.7	1.0	1.6	1.1	0.9	1.4	1.1	1.1	0.9	1.1	1.1	1.0	1.1
Health satisfaction	1.0	1.3	2.3	0.8	1.0	0.7	1.5	1.3	0.9	1.4	0.9	1.4	1.3	1.2	1.0
Medication for pain relief, constipation, heartburn	1.0	1.8	4.4	-1.2	-1.7	-0.5	-1.4	-1.6	-0.6	-2.1	-1.2	-1.3	-1.4	-1.4	-1.0
Loneliness, isolation	1.0	1.3	2.5	1.0	1.2	0.8	1.4	0.9	0.7	1.6	0.7	1.5	1.4	1.4	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	1.8	0.8	0.7	1.3	1.1	1.2	0.7	1.1	0.9	1.3	1.4	1.2	0.8
Guilty feelings	1.0	1.4	3.1	1.0	1.1	1.2	1.1	1.2	1.0	1.8	1.2	1.1	1.2	1.2	1.2
Happiness	0.9	1.1	3.9	0.0	0.0	2.0	1.2	0.8	1.7	0.7	-0.0	1.1	1.3	1.0	0.0
Prospective memory result	0.9	1.1	3.1	-0.9	-1.8	-1.0	-1.1	-1.1	-0.7	-1.1	-0.9	-1.2	-0.9	-0.9	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	2.6	-1.6	-1.3	-0.6	-1.1	-1.3	-0.5	-0.9	-1.6	-0.7	-1.0	-1.2	-1.6
Loud music exposure frequency	0.9	1.0	2.2	0.7	0.3	0.7	1.2	0.9	0.3	1.5	0.5	1.4	1.4	1.2	0.7
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	2.8	1.3	0.7	1.7	1.4	1.0	1.7	0.9	1.1	1.0	1.0	1.1	1.4
Comparative height size at age 10	0.9	5.1	20.8	-1.9	-2.8	-2.4	-1.7	-1.5	-1.9	-4.6	-1.4	-1.7	-1.8	-1.7	-1.8
Hypertension (Self-reported)	0.9	2.5	6.7	1.1	0.8	2.6	1.4	1.1	2.5	0.9	1.0	1.9	1.8	1.6	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.3	1.0	0.7	-0.3	0.5	1.1	-1.4	1.5	1.2	0.7	0.9	1.0	1.2
Smoking status: Previous	0.9	1.3	2.6	1.1	1.6	0.2	1.5	1.3	0.7	1.0	0.9	1.1	1.0	1.1	1.5
Medication for cholesterol	0.9	1.4	4.1	-0.7	-1.1	-1.7	-0.8	-0.7	-2.0	-1.3	-0.6	-1.2	-1.2	-1.1	-0.7
Mineral and other dietary supplements	0.9	1.2	1.8	1.3	1.4	0.4	1.0	1.1	0.5	1.3	1.1	1.1	0.9	1.1	1.3
Miserableness	0.9	1.6	3.6	0.6	0.4	1.4	1.5	1.3	1.9	1.7	0.2	1.4	1.5	1.3	0.5
Fractured/broken bones in last 5 years	0.9	1.2	2.3	1.2	1.5	0.2	1.1	1.1	0.1	1.4	1.3	1.1	1.0	1.1	0.7
Heel T-Score	0.8	6.2	16.0	-1.9	-4.0	4.0	-1.5	-1.9	4.0	-1.0	-2.6	-1.2	-0.6	-1.4	-2.3
Ever had hysterectomy (womb removed)	0.8	0.8	1.4	1.0	0.8	1.2	0.8	1.1	0.5	1.1	1.0	0.7	0.9	0.9	0.8
Medication: Co-codamol	0.8	0.9	3.4	0.7	1.8	-0.3	0.6	1.1	0.2	1.4	1.1	0.6	0.6	0.7	1.1
Diabetes (father)	0.8	0.9	4.1	-0.8	-0.2	-1.6	-0.7	-0.2	-2.0	0.3	-1.0	-0.4	-0.5	-0.6	-1.2
Medication: Atenolol	0.8	0.9	2.4	-1.2	-1.6	-0.0	-0.5	-0.7	0.6	-0.8	-1.4	-0.8	-0.6	-0.8	-1.5
Nervous feelings	0.8	1.5	2.7	1.2	1.3	0.3	0.9	1.4	-0.5	1.1	1.6	1.2	1.3	1.4	1.6
Forced vital capacity (FVC)	0.8	3.0	5.8	-1.8	-1.9	0.0	-1.2	-2.3	1.2	-2.4	-1.9	-1.5	-1.8	-1.9	-1.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.5	-1.1	-1.0	0.5	-1.2	-1.2	0.7	-0.8	-1.2	-1.1	-1.0	-1.1	-0.8
Glaucoma (self-reported)	0.8	1.0	1.8	0.6	1.0	1.3	1.1	1.1	1.2	0.4	0.6	1.2	1.2	1.0	0.5
Forced vital capacity (FVC), Best measure	0.8	2.8	4.5	-1.7	-1.7	0.2	-1.4	-2.1	1.2	-2.1	-1.7	-1.5	-1.8	-1.8	-1.7
Back pain experienced in last month	0.8	1.2	2.5	-1.5	-0.7	-0.9	-1.0	-1.3	-0.6	-0.7	-1.4	-0.9	-1.0	-1.1	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.3	-1.2	-1.3	1.2	-1.0	-2.1	1.8	-0.1	-1.4	-1.1	-1.1	-1.4	-1.0
Vascular/heart problems diagnosed by doctor	0.8	2.2	4.6	-1.1	-1.1	-2.1	-1.4	-1.3	-2.1	-0.9	-1.0	-1.8	-1.7	-1.6	-1.0
Ovarian Cancer	0.7	0.9	3.3	-1.2	-1.8	0.3	-0.1	-0.4	0.6	0.1	-1.6	-0.1	0.1	-0.3	-1.8
Triglycerides	0.7	1.1	2.0	-0.9	-1.0	-0.9	-1.3	-1.3	-0.1	-1.4	-0.7	-1.2	-1.2	-1.2	-0.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.4	-0.6	-0.8	-0.4	-1.1	-1.6	-0.4	-0.3	-0.3	-1.1	-1.2	-1.1	-0.3
Qualifications: CSEs or equivalent	0.7	0.9	3.1	1.1	1.8	0.7	0.4	0.6	0.9	0.8	1.3	0.3	0.2	0.4	1.6
Pain all over the body in last month	0.7	0.8	1.3	1.0	0.5	1.1	0.9	1.0	1.1	0.7	0.7	0.8	0.8	0.9	0.9
Alcohol intake versus 10 years previously	0.7	1.1	2.7	-1.1	-1.1	-0.3	-0.9	-1.6	0.1	-1.2	-1.5	-0.6	-0.8	-1.0	-1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	4.1	-1.5	-1.6	0.7	-0.8	-2.0	1.8	-1.8	-1.6	-1.2	-1.5	-1.6	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.7	3.2	0.2	0.1	1.8	0.8	0.4	1.6	0.6	0.2	0.7	0.9	0.7	0.3
Exposure to tobacco smoke at home	0.7	0.8	1.8	-0.9	-1.4	0.4	-0.8	-0.8	0.6	-0.9	-0.9	-0.9	-0.8	-0.9	-1.1
Birth weight of first child	0.7	1.3	4.3	-1.1	-1.3	-0.2	-1.4	-1.3	-0.2	-2.1	-0.7	-1.1	-1.2	-1.2	-0.7
Wheeze or whistling in the chest in last year	0.7	1.3	4.5	0.9	1.5	-0.1	1.2	1.4	-0.2	2.1	0.6	1.1	1.1	1.1	0.6
Alcohol intake frequency.	0.7	1.7	3.1	-1.1	-1.4	-1.8	-1.5	-1.1	-1.5	-1.1	-1.1	-1.1	-1.1	-1.1	-1.4
Average weekly champagne plus white wine intake	0.7	0.9	1.6	0.9	0.4	1.3	1.0	0.4	1.0	1.1	1.1	1.0	0.8	0.9	1.2
Medication: Blood pressure	0.7	1.3	2.1	0.9	1.0	1.4	1.1	1.0	1.5	1.2	0.8	1.3	1.4	1.3	0.6
Heart disease (siblings)	0.7	0.9	1.7	1.0	0.9	1.2	0.7	0.5	1.0	1.3	1.0	1.0	0.9	1.0	0.5
Alcohol drinker status: Previous	0.7	0.8	1.9	0.6	-0.3	0.9	1.1	1.4	0.8	0.9	-0.1	1.2	1.3	1.1	-0.4
Ulcerative Colitis (UC)	0.6	1.0	2.0	1.2	1.4	-0.2	1.0	1.1	-0.9	0.7	1.2	0.9	0.9	1.1	1.1
Verbal and Numeric Reasoning (VNR)	0.6	1.5	3.0	1.3	0.4	1.3	1.7	0.7	1.0	-0.2	1.2	1.5	1.4	1.4	1.5
Lupus	0.6	0.9	2.0	0.9	1.3	-1.3	0.2	1.0	-1.0	1.2	1.4	0.0	0.1	0.4	1.0
Angina	0.6	0.8	1.5	-1.0	-0.5	-0.9	-0.8	-1.2	-0.9	-0.5	-1.0	-0.9	-0.9	-1.0	-0.8
Vitamin and mineral supplements	0.6	0.8	1.6	1.1	0.8	-0.4	1.2	0.9	-0.4	1.2	1.0	0.7	0.8	0.9	0.8
Age when periods started (menarche)	0.6	1.5	2.6	-1.3	-0.7	-1.1	-1.4	-1.3	-0.7	-0.6	-1.1	-1.6	-1.5	-1.5	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.2	-1.1	-1.6	1.2	-1.0	-1.1	0.5	-1.2	-1.8	-0.7	-0.5	-0.8	-1.4
Hayfever, allergic rhinitis or eczema	0.6	1.2	5.3	0.9	0.7	2.3	0.8	0.5	2.1	0.6	0.5	0.7	0.8	0.7	0.6
Sitting height	0.6	4.1	15.3	-2.1	-2.8	-0.3	-1.5	-1.9	1.3	-3.9	-2.0	-1.4	-1.8	-1.9	-1.5
Asthma	0.6	1.1	2.0	1.1	1.3	0.0	1.2	1.4	-0.1	1.4	1.1	1.1	1.2	1.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	3.4	-1.5	-1.4	0.8	-1.0	-1.8	1.7	-1.5	-1.6	-1.1	-1.4	-1.5	-1.5
Pulse wave Arterial Stiffness index	0.6	0.7	2.6	-0.9	-1.0	-0.4	-0.5	-1.0	0.2	-1.6	-0.8	-0.7	-0.9	-0.9	-0.5
Birth weight	0.6	1.3	2.1	1.3	0.7	0.2	1.4	1.3	0.8	0.0	1.4	1.4	1.2	1.3	1.5
Comparative body size at age 10	0.6	1.6	2.9	1.2	1.3	1.3	1.3	1.5	1.2	1.7	1.0	1.1	1.3	1.2	1.0
Shortness of breath walking on level ground	0.6	0.7	1.8	0.7	0.4	0.6	1.1	0.4	0.5	1.0	0.9	0.8	0.8	0.8	1.3
Migraine (self-reported)	0.6	0.7	1.8	0.9	0.4	0.6	1.1	1.3	0.2	-0.1	0.5	1.1	1.1	1.1	0.3
Friendships satisfaction	0.6	0.8	1.4	1.0	0.5	0.2	1.1	1.2	0.2	1.2	0.8	0.8	1.0	1.0	0.9
Arm fat-free mass (left)	0.6	3.1	5.2	-2.1	-2.3	-0.8	-1.3	-1.7	1.0	-2.3	-2.2	-1.2	-1.6	-1.7	-1.9
Ever depressed for a whole week	0.6	0.7	1.8	0.8	1.1	-0.6	0.9	0.9	-0.4	1.4	0.7	0.7	0.8	0.7	0.9
Arm predicted mass (left)	0.6	3.2	5.3	-2.2	-2.2	-1.1	-1.4	-1.8	0.7	-2.3	-2.2	-1.3	-1.7	-1.8	-2.0
Alzheimer’s Disease (in father)	0.5	0.5	1.5	0.7	1.2	0.4	0.3	0.7	0.1	0.8	0.9	0.4	0.5	0.6	1.0
HDL Cholesterol	0.5	0.9	2.0	0.6	0.5	0.8	1.2	1.2	0.2	0.7	0.6	1.3	1.4	1.2	0.7
Smoking Status	0.5	1.2	4.9	-0.9	-0.1	-2.2	-0.8	-0.5	-1.4	-0.1	-1.3	-0.9	-1.0	-1.0	-1.0
Respiratory disease	0.5	1.1	2.2	1.1	1.4	-0.4	1.1	1.5	-0.2	1.3	1.1	1.1	1.0	1.1	0.5
Number of treatments/medications taken	0.5	0.9	4.3	-0.1	-0.3	1.3	1.0	0.5	2.1	0.6	0.1	1.1	1.2	0.9	0.1
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.6	-0.9	-0.5	-0.9	-0.8	-0.6	-0.7	-0.6	-1.2	-0.7	-0.6	-0.8	-1.3
Hearing difficulty/problems: Yes	0.5	0.7	1.9	-1.1	-1.2	0.8	-0.3	-0.7	1.4	-0.1	-1.0	-0.5	-0.5	-0.7	-0.7
Leg fat-free mass (left)	0.5	2.5	5.2	-1.9	-2.3	-0.7	-1.1	-1.5	0.9	-2.0	-1.9	-1.2	-1.5	-1.6	-1.7
Leg predicted mass (left)	0.5	2.5	5.0	-1.9	-2.2	-0.7	-1.1	-1.5	0.9	-1.9	-2.0	-1.1	-1.4	-1.5	-1.7
Allergy	0.5	1.1	2.1	-1.2	-0.8	-1.4	-1.2	-1.0	-1.1	-0.5	-0.8	-1.1	-1.1	-1.1	-0.6
Trunk fat-free mass	0.5	2.7	5.3	-2.0	-2.3	-0.7	-1.1	-1.4	1.1	-2.3	-2.1	-1.0	-1.4	-1.5	-1.8
Father’s age at death	0.5	0.6	1.0	-0.7	-0.9	-0.6	-0.7	-0.9	-0.8	-0.2	-0.7	-0.9	-0.9	-0.9	-1.0
Hair/balding pattern: Pattern 3	0.5	0.8	1.5	0.8	0.7	1.1	1.2	0.8	0.9	0.3	0.5	0.9	1.0	0.9	1.0
Illnesses of mother	0.5	0.7	3.3	-0.3	0.2	-1.8	-0.7	-0.4	-1.3	-0.5	-0.3	-0.7	-0.9	-0.7	-0.3
Trunk predicted mass	0.5	2.9	5.7	-2.0	-2.3	-0.8	-1.2	-1.5	0.9	-2.4	-2.1	-1.2	-1.6	-1.7	-1.8
Medication: Amlodipine	0.5	0.7	2.1	-0.8	-0.8	1.4	-0.2	-0.8	1.4	0.3	-1.1	-0.0	-0.1	-0.3	-1.1
Angina (self-reported)	0.5	0.6	1.2	-0.9	-0.4	-0.8	-0.7	-1.1	-0.7	-0.4	-0.9	-0.9	-0.8	-0.8	-0.8
Had major operations	0.5	0.5	1.0	0.6	0.8	-0.2	0.5	0.8	-0.8	1.0	0.8	0.7	0.6	0.7	0.8
Whole body fat-free mass	0.5	2.7	5.3	-1.9	-2.3	-0.7	-1.1	-1.5	1.0	-2.3	-2.0	-1.1	-1.5	-1.6	-1.7
Leg fat-free mass (right)	0.5	2.5	4.8	-1.9	-2.2	-0.5	-1.2	-1.5	1.0	-2.0	-1.9	-1.2	-1.5	-1.6	-1.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.5	-0.5	-1.6	-0.4	-0.5	-0.4	0.1	-1.3	-0.7	-0.7	-0.5	-0.6	-0.9
Asthma (self-reported)	0.5	1.0	2.1	1.0	1.1	0.2	1.1	1.3	0.1	1.4	0.9	1.0	1.1	1.1	0.4
Whole body water mass	0.5	2.9	5.7	-2.1	-2.4	-0.7	-1.2	-1.6	1.0	-2.3	-2.1	-1.2	-1.6	-1.7	-1.8
Leg predicted mass (right)	0.5	2.5	4.9	-1.9	-2.2	-0.6	-1.2	-1.5	1.0	-2.1	-1.9	-1.2	-1.5	-1.6	-1.6
Ever taken oral contraceptive pill	0.5	0.6	1.1	0.8	1.1	0.9	0.7	0.3	1.1	0.7	0.5	0.7	0.7	0.6	0.8
Basal metabolic rate	0.5	2.5	4.8	-1.9	-2.2	-0.8	-1.1	-1.4	0.9	-2.2	-2.0	-1.1	-1.4	-1.5	-1.7
Unable to work because of sickness or disability	0.5	0.6	2.2	-1.3	-0.6	-0.2	-0.2	-0.7	-0.0	-0.6	-1.5	-0.0	-0.1	-0.5	-1.4
Cholesterol lowering medication	0.5	0.7	1.8	0.7	0.7	0.8	0.9	0.5	1.3	0.8	0.3	1.1	1.0	0.9	0.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.1	0.8	0.3	1.1	0.3	0.8	1.4	1.1	0.7	0.2	0.4	0.5	0.7
Blood White Count	0.4	2.7	4.0	-1.9	-2.0	-1.1	-1.7	-2.0	-1.2	-1.6	-2.0	-1.4	-1.4	-1.6	-1.9
Pack years adult smoking proportion	0.4	0.5	1.2	0.6	0.5	0.5	1.1	1.1	0.5	0.5	0.3	0.9	0.9	0.8	0.3
Maternal smoking around birth	0.4	0.5	1.4	-0.4	-0.3	-0.7	-0.9	-0.6	-1.2	-0.1	0.0	-1.0	-1.0	-0.9	-0.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.2	0.5	0.5	0.3	1.0	1.1	0.3	0.4	0.5	0.8	1.0	0.9	0.5
Impedance of leg (left)	0.4	1.7	12.3	0.2	0.8	-2.3	-0.3	0.6	-3.5	-1.3	0.4	-0.2	-0.2	0.0	-0.2
Hearing difficulty/problems with background noise	0.4	0.6	1.5	-1.0	-1.1	0.6	-0.1	-0.7	0.8	-0.3	-1.2	-0.1	-0.2	-0.4	-1.2
Pulse rate	0.4	0.7	2.1	-0.5	-0.7	0.3	-0.8	-1.5	0.6	-0.7	-0.8	-1.0	-1.0	-1.0	-0.2
Depression (self-reported)	0.4	0.4	1.4	-1.2	-0.9	-0.1	-0.8	-0.5	0.1	-0.3	-0.8	-0.2	-0.4	-0.6	-1.0
Headache pain in last month	0.4	0.6	1.3	-0.1	0.1	0.9	1.1	0.6	1.1	0.0	-0.4	1.1	1.1	0.8	-0.5
Arm fat-free mass (right)	0.4	2.2	4.5	-1.7	-2.1	-0.7	-1.1	-1.4	1.0	-2.1	-1.7	-1.0	-1.3	-1.4	-1.6
Number of children fathered	0.4	0.4	1.0	1.0	0.2	0.6	0.9	0.8	0.7	0.2	0.8	0.5	0.6	0.7	0.7
Emphysema/chronic bronchitis	0.4	0.4	1.1	0.5	0.5	0.8	1.1	0.6	0.2	0.6	0.3	0.8	0.9	0.8	0.2
Ever had bowel cancer screening	0.4	0.5	1.8	-0.7	-1.3	-0.4	-1.0	-0.7	-0.3	-0.8	-0.1	-0.8	-0.7	-0.6	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.7	-0.1	0.1	1.0	0.7	0.2	1.6	0.8	-0.2	0.4	0.5	0.3	-0.1
Osteoarthritis (self-reported)	0.4	0.6	1.3	0.6	0.7	0.5	1.0	1.1	0.2	0.5	0.6	0.8	0.8	0.8	0.8
Medication: Paracetamol	0.4	0.6	2.2	0.3	0.8	0.6	0.8	0.9	1.1	1.5	0.1	0.8	0.8	0.6	0.2
Ever smoked	0.4	0.7	1.9	-1.1	-0.5	-0.8	-0.6	-0.9	0.1	-0.7	-1.4	-0.7	-0.8	-0.9	-0.8
Risk taking	0.4	0.6	2.5	-0.6	-0.1	-1.6	-0.5	-0.7	-1.4	-0.6	-0.3	-0.5	-0.7	-0.6	-0.2
Supplements: Calcium	0.4	0.4	1.1	0.8	0.7	0.3	0.3	1.0	-0.2	1.0	0.9	0.4	0.6	0.7	0.5
Bipolar Disorder (2018)	0.3	0.4	1.7	-0.8	-0.6	0.5	-0.3	-0.3	0.2	-0.3	-1.3	0.1	0.1	-0.2	-1.2
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.0	1.1	0.7	0.6	1.4	0.5	0.2	0.2	0.7	1.3	1.1	1.0	0.9
Reaction Time	0.3	0.6	1.8	-1.4	-0.8	-0.3	-0.8	-0.8	-0.3	-0.9	-1.0	-0.5	-0.5	-0.7	-0.8
Age at First Birth	0.3	0.4	1.0	0.2	-0.6	1.0	0.9	0.3	0.5	0.2	-0.4	0.9	1.0	0.7	-0.1
Body Mass Index (BMI) (2010)	0.3	0.3	0.8	-0.7	0.0	-0.5	-0.6	-0.4	-0.2	-0.3	-0.7	-0.8	-0.9	-0.9	-0.4
Fasting Glucose	0.3	0.4	1.4	-0.2	-1.1	1.2	-0.1	-0.2	1.1	-0.6	-0.3	0.2	0.1	-0.1	-0.1
Primary Biliary Cirrhosis	0.3	0.5	1.9	-0.3	-0.4	-1.1	-0.5	-0.1	-1.4	-0.3	0.0	-1.0	-0.8	-0.6	-0.2
Allergy or Eczema	0.3	0.7	3.3	0.4	0.3	1.8	0.6	0.2	1.8	0.4	-0.0	0.5	0.5	0.4	0.2
Lung FVC	0.3	1.6	8.9	-0.5	-0.1	2.2	-0.3	-1.7	3.0	0.6	-0.7	-0.3	-0.7	-0.8	-0.3
Hand grip strength (left)	0.3	0.7	1.8	-0.7	-0.4	-1.3	-0.6	-0.6	-0.9	-1.2	-0.6	-0.8	-1.1	-0.9	-0.6
Relative age of first facial hair	0.3	0.7	2.1	-1.0	-1.0	-0.2	-0.5	-0.3	-0.3	-1.0	-1.2	-0.7	-0.6	-0.7	-1.4
Systolic blood pressure, automated reading	0.3	0.9	2.6	0.9	0.4	1.6	0.6	0.8	1.4	0.4	1.0	0.9	0.7	0.8	0.7
Supplements: Zinc	0.3	0.3	0.8	0.4	0.9	0.1	0.4	0.8	0.4	0.4	0.4	0.7	0.7	0.7	0.5
Severe depression (siblings)	0.3	0.4	0.9	-0.2	-1.0	0.7	-0.7	-0.4	0.9	-0.2	-0.2	-0.8	-0.6	-0.5	-0.1
Impedance of leg (right)	0.3	1.6	11.3	-0.1	0.3	-2.4	-0.2	0.6	-3.4	-1.3	0.1	-0.2	-0.2	-0.1	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.9	-0.8	-0.2	-0.1	-0.6	-0.5	-0.1	-0.2	-0.7	-0.5	-0.6	-0.6	-1.0
Serious illness, injury or assault to yourself	0.3	0.4	2.7	-0.0	-0.2	-1.2	-0.1	0.0	-1.6	-0.2	0.2	-0.2	-0.1	-0.0	-0.2
Multivitamins +/- minerals	0.3	0.4	2.0	-0.4	-0.7	1.1	-0.3	0.1	1.4	-0.7	-0.5	-0.0	-0.0	-0.1	-0.2
Number of incorrect matches in round	0.3	0.6	3.7	-0.3	-0.2	1.4	-0.2	-0.2	1.9	0.8	-0.3	0.2	0.2	0.0	-0.3
Weight	0.3	1.3	2.7	-1.4	-1.4	-0.9	-0.7	-0.9	0.4	-1.6	-1.4	-0.7	-1.0	-1.1	-1.3
Impedance of arm (right)	0.3	1.6	11.5	-0.2	0.0	-2.0	-0.5	0.5	-3.4	-1.3	0.1	-0.6	-0.4	-0.2	-0.6
Noisy workplace	0.3	0.4	2.3	0.0	-0.2	-1.5	-0.0	-0.2	-1.5	0.0	-0.2	-0.2	-0.2	-0.2	-0.3
Impedance of arm (left)	0.3	1.4	8.5	0.8	0.6	-1.3	0.4	1.5	-2.9	-0.7	0.9	0.3	0.6	0.8	0.2
Peak expiratory flow (PEF)	0.3	0.7	1.6	-0.9	-0.6	-0.1	-0.7	-1.3	0.5	-0.7	-0.6	-0.9	-1.2	-1.1	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.2	-0.2	0.1	1.1	0.4	0.5	0.9	0.6	-0.2	0.8	0.6	0.4	-0.1
Medication: Blood pressure	0.3	0.5	1.8	-0.7	-0.8	0.9	-0.1	-0.6	1.3	-0.2	-0.9	0.2	0.2	-0.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.6	-0.5	-0.5	-0.6	-0.5	-0.5	-0.8	-0.6	-0.4	-0.5	-0.6	-0.6	-0.7
Arm predicted mass (right)	0.3	1.7	3.6	-1.6	-1.9	-0.5	-0.8	-1.2	1.3	-1.8	-1.5	-0.7	-1.1	-1.2	-1.3
Arm fat percentage (left)	0.3	1.2	2.2	0.9	1.2	0.7	1.3	1.3	0.8	1.5	0.9	1.2	1.1	1.1	0.8
Eye problems/disorders: Glaucoma	0.3	0.3	1.2	-0.5	-0.6	0.9	-0.1	-0.4	0.8	-1.1	-0.3	0.1	0.0	-0.1	-0.4
High cholesterol (Self-reported)	0.3	0.6	2.0	-1.1	-1.0	0.8	-0.2	-0.8	1.4	-0.1	-1.0	-0.1	-0.1	-0.3	-0.8
Illnesses of father: High blood pressure	0.3	0.4	1.0	-0.0	-0.1	0.5	0.7	0.7	0.5	1.0	-0.4	0.8	0.8	0.5	-0.5
Diastolic blood pressure, automated reading	0.3	1.0	3.9	1.0	0.1	1.9	0.7	0.4	2.0	0.5	0.8	0.7	0.6	0.6	1.0
Impedance of whole body	0.3	1.7	12.4	0.4	0.6	-2.0	-0.0	1.0	-3.5	-1.3	0.6	-0.0	0.1	0.3	-0.1
Schizophrenia (2018)	0.2	0.3	0.9	0.4	1.0	0.3	0.1	0.9	-0.5	0.8	0.7	0.3	0.2	0.3	0.3
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	-0.3	-0.3	-0.8	-0.5	-0.1	-0.6	-0.4	-0.4	-0.7	-0.4	-0.4	-0.4
Crohns Disease (2017)	0.2	0.5	1.8	-0.4	-1.3	-0.5	-0.7	-0.4	-0.1	-1.3	-0.1	-0.5	-0.6	-0.5	-0.5
Irritable Bowel Disease (IBD)	0.2	0.4	0.9	0.9	0.4	-0.2	0.6	0.9	-0.4	-0.0	0.9	0.6	0.6	0.8	0.6
Neuroticism (2016)	0.2	0.4	1.4	-0.4	-1.2	0.4	0.1	-0.4	1.0	0.5	-0.6	-0.0	0.1	-0.1	-0.9
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.7	0.0	0.6	0.8	-0.5	-0.1	0.6	0.4	0.1	-0.7	-0.6	-0.4	0.1
Ulcerative Colitis	0.2	0.3	0.8	0.6	0.9	0.2	0.5	0.5	-0.6	0.0	0.7	0.4	0.4	0.6	0.8
Systolic Blood Pressure	0.2	0.8	2.5	-0.9	-1.1	1.3	-0.7	-0.4	1.6	-0.8	-0.7	-0.3	-0.4	-0.6	-1.0
Cardiovascular Disease	0.2	0.8	5.5	-0.0	0.0	1.5	0.1	0.3	2.3	0.8	-0.1	0.6	0.6	0.3	-0.1
Lung FEV1/FVC ratio	0.2	1.0	3.7	0.1	-0.1	1.8	0.9	0.3	1.9	1.3	-0.1	0.8	1.1	0.7	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	0.2	0.9	0.3	0.3	0.8	0.3	0.6	-0.0	0.7	0.6	0.5	-0.0
Relative age voice broke	0.2	0.4	1.4	0.5	0.1	1.2	0.7	0.7	0.6	0.5	0.1	0.6	0.6	0.5	-0.0
Taking other prescription medications	0.2	0.3	0.6	-0.6	-0.5	-0.1	-0.7	-0.8	0.3	-0.4	-0.2	-0.7	-0.6	-0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.6	-0.6	0.2	0.1	-0.3	0.6	0.2	-0.6	0.2	0.1	-0.1	-0.6
Medication: Levothyroxine sodium	0.2	0.4	0.9	0.9	0.8	0.6	0.3	0.3	0.9	0.2	0.8	0.2	0.2	0.3	1.0
Body mass index (BMI)	0.2	0.8	3.2	0.4	0.7	0.9	0.9	0.4	1.8	1.6	0.3	0.8	0.6	0.6	0.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.6	0.5	-0.2	-0.8	0.5	0.7	-0.4	0.4	0.2	0.3	0.5	0.4	0.4
Financial difficulties in last 2 years	0.2	0.2	0.4	0.6	0.1	-0.4	0.6	0.4	-0.2	0.6	0.6	0.3	0.5	0.5	0.4
Heart attack	0.2	0.3	1.2	0.7	0.7	0.2	0.3	-0.1	0.4	0.7	1.1	0.1	0.2	0.3	0.9
Medication: Ramipril	0.2	0.3	0.9	-0.5	-0.4	0.8	0.1	-0.2	0.9	-0.7	-0.5	0.5	0.3	0.1	-0.6
Medication: Simvastatin	0.2	0.3	1.5	-0.2	0.3	0.8	0.2	-0.2	0.9	1.2	-0.1	0.6	0.5	0.3	-0.0
Fluid intelligence score	0.2	0.4	1.0	0.5	-0.2	0.8	1.0	0.4	0.8	-0.7	0.3	0.7	0.7	0.7	0.6
Illnesses of siblings	0.2	0.2	0.9	-0.5	-0.2	-0.7	0.1	-0.2	-0.9	-0.8	-0.6	-0.3	-0.2	-0.3	-0.2
Arm fat percentage (right)	0.2	0.8	1.7	0.7	1.0	0.5	1.0	1.0	0.7	1.3	0.7	1.0	0.8	0.9	0.6
Medication: Cholesterol lowering	0.2	0.3	1.2	-0.7	-1.1	0.5	0.0	-0.7	1.0	-0.5	-0.5	-0.2	-0.0	-0.2	-0.3
Length of working week for main job	0.2	0.3	0.6	-0.7	-0.4	-0.1	-0.3	-0.7	0.0	-0.7	-0.5	-0.5	-0.5	-0.5	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.8	0.1	0.4	0.2	0.9	0.4	-0.2	0.2	0.1	0.6	0.6	0.5	0.2
Blood clot in the leg (DVT)	0.2	0.3	0.6	0.6	-0.1	-0.5	0.6	0.3	-0.3	0.8	0.5	0.5	0.5	0.6	0.5
Medication: Paracetamol	0.2	0.3	1.6	-0.0	0.7	0.5	0.4	0.4	0.8	1.2	-0.1	0.5	0.4	0.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.3	0.6	0.7	-0.8	0.1	0.6	-1.2	0.2	0.6	-0.1	-0.1	0.1	0.5
High blood pressure (siblings)	0.2	0.2	1.2	0.1	-0.6	0.6	-0.4	-0.3	1.1	0.5	-0.0	-0.2	-0.3	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.9	-0.0	-0.4	0.9	0.1	0.2	1.4	-0.3	0.1	0.3	0.2	0.2	0.0
Pulse wave peak to peak time	0.2	0.3	0.7	0.5	0.6	0.1	0.2	0.7	-0.5	0.8	0.4	0.4	0.5	0.5	0.1
Eye problems/disorders: None of the above	0.2	0.2	0.9	0.2	0.4	1.0	0.1	0.3	0.9	-0.2	-0.1	0.2	0.2	0.2	0.1
Neck or shoulder pain in last month	0.2	0.3	0.7	0.6	0.9	-0.7	-0.1	0.4	-0.3	0.9	0.6	-0.0	-0.1	0.2	0.4
Medication: Allopurinol	0.2	0.2	0.6	-0.5	-0.6	-0.8	-0.2	-0.5	-0.2	-0.6	-0.5	-0.5	-0.4	-0.4	-0.4
Pulse rate, automated reading	0.2	0.5	1.3	-0.6	-0.9	-0.3	-0.6	-1.0	-0.1	-1.1	-0.9	-0.7	-0.7	-0.7	-0.4
Overall health rating	0.2	0.4	1.3	-0.0	0.5	0.1	0.7	0.8	-0.1	1.1	-0.0	1.0	0.9	0.7	-0.1
Age at last live birth	0.2	0.3	0.8	0.5	0.0	0.4	0.9	0.3	0.2	0.1	0.5	0.6	0.5	0.6	0.6
Family relationship satisfaction	0.2	0.3	0.5	0.5	0.1	0.4	0.7	0.7	0.3	0.4	0.2	0.6	0.7	0.7	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	-0.5	-0.8	-0.3	0.2	-0.2	0.2	0.1	-0.8	0.0	-0.1	-0.2	-0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.9	0.5	0.9	0.3	0.4	0.8	0.4	-0.1	0.2	0.3	0.2	0.3	0.6
Illnesses of father: Heart disease	0.2	0.3	1.5	0.5	1.2	-0.4	0.5	0.2	-0.3	0.4	0.6	0.1	0.0	0.1	0.6
Long-standing illness, disability or infirmity	0.2	0.3	0.9	-0.9	-0.5	0.1	-0.6	-1.0	0.4	-0.2	-0.8	-0.2	-0.4	-0.5	-0.7
Qualifications: nursing, teaching	0.2	0.4	2.3	-0.5	-1.5	0.4	-0.1	-0.5	0.8	-0.4	-0.5	-0.2	-0.1	-0.2	-0.6
Wears glasses or contact lenses	0.2	0.2	0.9	-0.2	-0.5	-0.6	0.4	-0.3	-0.9	-0.4	-0.2	0.1	0.1	0.0	-0.5
Hearing aid user	0.2	0.2	0.7	0.0	-0.6	-0.6	-0.2	-0.6	0.1	-0.8	0.0	-0.4	-0.5	-0.3	0.1
Mother’s age at death	0.2	0.3	1.6	-0.2	-0.5	1.0	0.0	0.2	0.7	-1.2	-0.0	0.1	0.2	0.1	-0.2
Financial situation satisfaction	0.2	0.2	0.5	0.2	-0.2	0.6	0.7	0.4	0.5	0.4	0.0	0.7	0.7	0.6	0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	-0.3	-0.2	-0.5	-0.8	-0.4	-0.9	0.1	-0.2	-0.7	-0.6	-0.5	-0.3
Commuting to job workplace: Public transport	0.2	0.3	0.8	0.6	0.7	0.9	0.7	0.3	0.5	0.2	0.2	0.5	0.4	0.5	0.6
Medication: Bendroflumethiazide	0.2	0.3	1.7	-0.1	-0.2	0.9	0.4	0.2	1.3	0.0	-0.0	0.6	0.5	0.4	0.1
Medication: Atorvastatin	0.2	0.2	1.1	-0.3	-0.4	0.3	0.2	-0.3	1.0	-0.8	-0.6	-0.1	-0.0	-0.2	-0.4
Average weekly beer plus cider intake	0.2	0.2	0.5	0.5	0.7	-0.1	0.6	0.3	0.0	0.2	0.6	0.6	0.3	0.4	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.8	-0.1	-0.9	0.9	0.1	-0.5	0.9	-0.4	-0.2	0.0	0.0	-0.0	0.1
Commuting to job workplace: Cycle	0.2	0.3	1.1	0.4	0.3	0.9	0.5	0.3	1.1	0.6	0.2	0.4	0.3	0.3	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	0.6	-0.2	-0.5	0.7	0.4	-0.3	0.9	0.4	0.6	0.7	0.7	0.4
Pack years of smoking	0.2	0.3	0.7	0.5	0.4	0.7	0.9	0.7	0.5	0.2	0.2	0.6	0.6	0.6	0.2
Bipolar Disorder or Schizophrenia	0.1	0.1	0.3	-0.2	0.4	0.6	-0.0	0.5	-0.3	0.5	-0.3	0.3	0.2	0.1	-0.5
Depressed Affect (Nagel 2018)	0.1	0.1	0.5	0.0	0.0	0.5	0.3	0.4	0.5	0.7	-0.2	0.3	0.5	0.3	-0.0
Schizophrenia vs Biploar Disorder	0.1	0.2	1.3	0.0	0.0	0.7	0.4	0.2	1.1	-0.4	0.2	-0.0	-0.1	-0.1	0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.5	0.3	0.4	-0.3	-0.1	0.7	-0.5	0.3	0.3	-0.3	-0.0	0.0	0.4
Major Depression (MDD)	0.1	0.1	0.3	-0.4	-0.1	0.1	0.2	0.4	0.2	-0.3	-0.5	0.2	0.1	-0.1	-0.6
Coronary Artery Disease (CAD)	0.1	0.2	0.4	-0.6	-0.3	0.1	-0.4	-0.3	0.1	0.0	-0.6	-0.3	-0.4	-0.6	-0.4
Crohns Disease (2012)	0.1	0.2	0.8	0.6	-0.1	0.0	0.1	0.4	0.5	-0.8	0.9	0.0	0.0	0.1	0.7
LDL Cholesterol	0.1	0.2	0.6	0.2	0.8	-0.6	0.2	-0.0	0.0	0.6	0.4	-0.3	-0.2	-0.1	0.4
Rheumatoid Arthritis	0.1	0.1	0.6	-0.0	-0.8	0.4	-0.3	-0.0	-0.5	0.4	-0.3	-0.0	0.1	0.1	-0.3
Blood Eosinophil Count	0.1	0.5	0.9	-0.9	-0.5	-0.9	-0.9	-0.4	-0.9	-0.6	-0.4	-0.9	-0.7	-0.7	-0.5
Blood Platelet Count	0.1	1.5	3.6	1.0	1.2	0.5	1.1	1.1	0.7	1.9	1.3	1.3	1.3	1.3	1.3
BMI	0.1	0.5	3.4	0.3	0.4	0.2	0.5	0.3	1.1	1.8	0.1	0.5	0.4	0.4	0.3
Waist Hip Ratio (WHR)	0.1	0.2	0.8	0.0	0.5	-0.9	0.0	0.4	-0.9	-0.7	-0.1	0.2	0.2	0.1	-0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.5	-0.4	0.4	-0.1	-0.4	-0.7	-0.3	0.2	-0.3	-0.3	-0.6	-0.6	-0.3
Hair Pigment	0.1	1.5	3.4	-1.2	-1.1	0.4	-1.1	-1.8	1.7	-0.7	-1.4	-1.1	-1.2	-1.4	-0.9
Tanning	0.1	0.7	3.0	0.6	0.8	-1.7	-0.3	-0.3	-1.1	-0.5	1.1	-0.5	-0.7	-0.4	0.9
Medication: Metformin	0.1	0.1	0.4	-0.0	0.5	-0.5	-0.2	-0.3	-0.6	0.3	0.1	-0.1	-0.3	-0.2	0.0
Diabetes (mother)	0.1	0.1	0.4	-0.2	0.6	-0.5	-0.2	0.1	-0.3	0.4	0.1	0.2	0.0	0.0	0.1
Hand grip strength (right)	0.1	0.4	0.9	-0.4	-0.2	-0.7	-0.3	-0.6	-0.7	-1.0	-0.5	-0.4	-0.7	-0.6	-0.5
Fed-up feelings	0.1	0.1	0.4	-0.4	-0.3	0.2	0.3	0.3	0.5	0.4	-0.7	0.3	0.3	0.1	-0.5
Trunk fat mass	0.1	0.3	1.1	-0.5	-0.5	-0.8	-0.1	-0.1	-0.2	-1.0	-0.3	-0.1	-0.3	-0.3	-0.6
Past tobacco smoking	0.1	0.1	0.4	0.3	-0.4	0.5	-0.4	-0.0	-0.2	0.0	0.7	-0.1	-0.0	0.1	0.0
Alcohol usually taken with meals	0.1	0.2	1.0	0.3	-0.5	1.0	0.1	-0.3	0.4	-0.0	0.5	-0.1	0.1	0.1	0.3
Had other major operations	0.1	0.2	0.5	-0.6	-0.3	0.5	0.4	0.0	0.3	-0.3	-0.7	0.3	0.3	0.1	-0.5
Diabetes (self-reported)	0.1	0.1	0.7	0.4	0.8	0.2	0.2	-0.1	0.1	0.1	0.5	0.2	0.0	0.1	0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.9	-0.0	0.7	0.6	0.1	-0.2	0.3	0.9	0.2	0.3	0.1	0.1	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.7	0.1	0.9	-0.4	0.4	0.2	-0.4	-0.4	0.0	0.3	-0.0	0.0	0.1
Falls in the last year	0.1	0.1	0.4	0.2	0.3	-0.6	-0.1	0.3	-0.0	-0.6	0.3	-0.0	-0.0	0.0	0.2
Number of live births	0.1	0.1	0.4	-0.4	-0.3	-0.4	-0.2	-0.5	-0.2	0.6	-0.2	-0.1	-0.1	-0.2	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.5	-0.2	-0.6	1.1	0.7	0.0	1.2	-0.1	-0.3	0.3	0.3	0.1	-0.1
Lung cancer (father)	0.1	0.1	0.5	0.0	-0.2	-0.3	-0.3	-0.6	-0.3	-0.1	-0.1	-0.7	-0.5	-0.4	-0.0
Tense / ‘highly strung’	0.1	0.1	0.2	-0.3	0.2	-0.5	-0.4	-0.1	-0.3	0.3	0.3	-0.3	-0.3	-0.2	0.2
Pulse wave reflection index	0.1	0.1	0.2	-0.0	0.1	0.3	0.3	0.3	0.5	0.5	0.2	0.5	0.2	0.3	0.0
Gout (self-reported)	0.1	0.2	0.4	0.4	0.4	-0.5	0.6	0.3	0.2	0.4	0.4	0.2	0.2	0.3	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.6	0.3	0.5	-0.4	-0.3	-0.0	0.2	-0.2	0.5	-0.2	-0.3	-0.1	0.8
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.8	-0.2	0.1	-0.8	-0.2	-0.0	-0.9	0.4	-0.4	-0.2	-0.1	-0.1	-0.5
Body fat percentage	0.1	0.2	0.4	0.3	0.6	-0.3	0.6	0.7	-0.1	0.3	0.5	0.6	0.4	0.5	0.3
Leg fat percentage (right)	0.1	0.3	0.7	0.3	0.8	-0.1	0.8	0.6	0.4	0.8	0.4	0.8	0.6	0.6	0.2
Age at first live birth	0.1	0.2	0.7	0.3	-0.2	0.4	0.8	0.3	-0.1	-0.6	0.0	0.7	0.7	0.5	0.2
Qualifications: College or University degree	0.1	0.2	0.6	-0.5	-0.8	0.1	-0.1	-0.5	0.4	-0.3	-0.5	-0.2	-0.2	-0.3	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.8	0.5	0.4	-0.2	-0.0	0.5	-0.3	0.9	0.5	0.2	0.1	0.2	0.3
Medication: Omeprazole	0.1	0.1	0.6	0.4	0.2	0.6	-0.2	0.3	0.8	0.5	0.2	-0.1	0.0	0.1	0.2
Mean time to correctly identify matches	0.1	0.3	0.6	-0.7	-0.8	-0.2	-0.7	-0.7	0.1	-0.7	-0.4	-0.4	-0.3	-0.4	-0.3
Heart disease (mother)	0.1	0.2	0.9	0.6	0.5	-0.2	-0.1	0.2	-0.0	0.3	0.7	-0.1	0.0	0.1	0.9
Supplements: Vitamin C	0.1	0.1	0.5	0.3	0.7	0.5	0.0	0.1	0.0	0.1	0.4	0.3	0.2	0.3	0.5
Knee pain experienced in last month	0.1	0.1	0.5	-0.3	0.2	-0.7	-0.1	-0.5	-0.3	-0.2	-0.1	-0.3	-0.4	-0.3	0.4
Mood swings	0.1	0.2	0.7	-0.7	-0.6	0.0	-0.3	-0.1	0.3	0.1	-0.8	-0.2	-0.1	-0.2	-0.8
Diabetes diagnosed by doctor	0.1	0.2	0.7	-0.2	0.2	-0.3	-0.4	-0.8	-0.4	0.1	-0.1	-0.3	-0.5	-0.4	-0.3
Eye problems/disorders: Cataract	0.1	0.1	0.5	0.3	0.4	-0.1	-0.1	0.1	0.3	0.4	0.7	-0.2	-0.3	-0.1	0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	0.7	0.5	-0.4	0.5	0.5	0.4	0.2	0.4	0.4	0.4	0.4	0.6
Breast cancer (self-reported)	0.1	0.2	0.5	-0.3	-0.2	0.7	-0.0	0.2	0.4	-0.6	-0.5	0.1	0.2	0.1	-0.6
Medication: Gliclazide	0.1	0.1	0.4	-0.1	-0.1	0.5	0.2	0.3	0.6	0.5	-0.4	0.3	0.4	0.3	-0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	0.5	0.4	0.3	0.4	0.1	-0.1	0.1	0.5	0.4	0.5	0.2
Arm fat mass (left)	0.1	0.2	0.8	0.2	0.3	0.2	0.6	0.5	0.9	0.5	0.2	0.6	0.4	0.4	0.2
Number of self-reported non-cancer illnesses	0.1	0.2	1.0	-0.1	-0.2	1.0	0.1	-0.1	0.9	0.3	0.3	0.3	0.4	0.3	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.6	-0.5	-0.1	-0.3	-0.3	-0.5	-0.4	-0.8	-0.1	-0.4	-0.4	-0.4	-0.3
Leg fat percentage (left)	0.1	0.4	1.0	0.5	1.0	0.1	0.8	0.7	0.5	0.8	0.5	0.9	0.6	0.7	0.4
Pain experienced in last month	0.1	0.1	0.6	0.4	0.2	0.1	0.2	0.2	-0.2	-0.4	0.7	-0.1	0.1	0.1	0.8
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.6	0.3	0.3	0.1	0.0	-0.5	0.2	0.4	0.8	-0.2	-0.1	0.0	0.6
Depression (Nagel 2018)	0.0	0.0	0.1	-0.3	0.2	-0.1	-0.3	0.0	-0.2	-0.1	-0.3	-0.1	-0.0	-0.1	-0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.1	0.1	-0.4	0.3	0.2	-0.2	0.3	-0.4	0.3	-0.2	0.0	-0.1	-0.2	-0.3
Blood Red Count	0.0	0.4	1.1	-0.6	-0.8	-0.5	-1.1	-0.5	-1.0	-0.4	-0.3	-0.3	-0.3	-0.3	-0.5
Hypothyroidism (self reported)	0.0	0.1	0.2	0.2	0.4	-0.3	-0.4	-0.1	0.1	0.1	0.2	-0.2	-0.4	-0.2	0.4
Chronotype (morning person)	0.0	0.1	0.4	0.2	-0.4	-0.0	-0.3	0.1	0.6	-0.2	0.3	-0.4	-0.2	-0.1	0.2
Trunk fat percentage	0.0	0.1	0.4	0.1	0.3	-0.6	0.4	0.5	-0.5	-0.3	0.4	0.4	0.2	0.3	0.0
Waist circumference	0.0	0.1	0.5	-0.4	0.2	-0.7	-0.0	-0.3	0.2	-0.1	-0.3	-0.0	-0.3	-0.3	-0.5
Hip circumference	0.0	0.1	0.6	-0.1	0.4	-0.8	0.0	0.0	0.3	-0.1	0.0	-0.0	-0.4	-0.2	0.2
Arm fat mass (right)	0.0	0.1	0.7	0.1	0.2	0.1	0.5	0.4	0.8	0.4	0.1	0.4	0.2	0.2	0.1
Whole body fat mass	0.0	0.2	0.6	-0.5	-0.4	-0.7	-0.1	-0.1	-0.0	-0.8	-0.3	-0.1	-0.4	-0.3	-0.5
Leg fat mass (right)	0.0	0.2	0.4	-0.6	-0.4	-0.5	-0.2	-0.3	0.4	-0.4	-0.5	-0.1	-0.4	-0.4	-0.6
Number of operations (self-reported)	0.0	0.1	0.5	-0.3	-0.1	-0.1	-0.3	0.3	-0.7	0.1	0.3	0.1	0.0	0.1	-0.0
Leg fat mass (left)	0.0	0.2	0.4	-0.6	-0.3	-0.4	-0.2	-0.3	0.4	-0.5	-0.5	-0.1	-0.4	-0.4	-0.5

Hub : Genes

CDC20P1

Models

Trait associations