TWAS hub - CDC25C

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.027	0.0158	0.0046	0.031	0.031	0.030	NA	0.029	0.00016	0.00017	0.00025	NA	0.0003
2	TCGA	Thyroid Carcinoma	0.033	0.0190	0.0053	0.015	0.013	0.012	NA	0.018	0.01300	0.01800	0.02200	NA	0.0065

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	15.7	50.8	70.3	8.4	5.6
Pulse rate	9.8	16.5	25.0	5.0	2.8
Handedness (chirality/laterality): Left-handed	9.7	11.7	13.1	3.2	3.6
Qualifications: A levels/AS levels or equivalent	9.3	20.6	25.1	5.0	4.0
Friendships satisfaction	8.6	10.6	11.3	-3.2	-3.4
Qualifications: CSEs or equivalent	8.0	10.6	11.1	-3.3	-3.2
Medication: Ventolin 100micrograms inhaler	7.2	9.3	11.5	-2.6	-3.4
Emphysema/chronic bronchitis	7.2	8.1	11.3	-2.2	-3.4
Hayfever, allergic rhinitis or eczema	6.6	14.2	19.9	-2.9	-4.5
Number of live births	6.6	9.4	11.8	-3.4	-2.6
Happiness	6.6	8.0	9.4	-3.1	-2.6
Commuting to job workplace: Walk	6.6	7.2	10.6	3.3	1.9
Eye problems/disorders: Cataract	6.5	7.6	9.3	-3.1	-2.4
Allergy	6.2	14.2	19.3	3.0	4.4
Mineral and other dietary supplements	5.7	7.7	8.2	2.7	2.9
Miserableness	5.7	9.9	10.6	-3.0	-3.3
Allergy or Eczema	5.3	13.9	19.0	-3.0	-4.4
Fluid intelligence score	5.3	10.9	11.0	3.3	3.3
Hearing difficulty/problems with background noise	5.2	8.3	11.0	-2.4	-3.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.1	6.0	7.1	-2.2	-2.7
Triglycerides	4.9	8.1	8.2	-2.8	-2.9
Mouth/teeth dental problems: Dentures	4.8	8.2	8.4	-2.8	-2.9
Number of incorrect matches in round	4.7	7.8	9.2	-3.0	-2.5
Asthma (self-reported)	4.7	9.3	11.1	-2.7	-3.3
Respiratory disease	4.5	9.9	12.3	-2.7	-3.5
Average weekly spirits intake	4.5	5.6	6.0	2.5	2.3
Medication: Ramipril	4.4	5.6	7.4	-2.7	-2.0
Commuting to job workplace: Public transport	4.2	5.0	7.8	2.8	1.5
Major Depression (MDD)	4.1	4.9	6.2	-2.5	-1.9
Asthma	4.0	8.0	9.5	-2.5	-3.1
Chronotype (morning person)	3.9	9.0	10.5	3.2	2.7
Bipolar Disorder or Schizophrenia	3.8	9.3	10.0	3.2	2.9
Shortness of breath walking on level ground	3.8	4.5	5.3	2.3	2.0
Age at First Birth	3.7	5.4	6.2	2.5	2.1
Qualifications: NVQ or HND or HNC or equivalent	3.7	4.4	6.1	-2.5	-1.7
Age started oral contraceptive pill	3.7	4.6	5.3	-2.3	-2.0
Heart disease (mother)	3.6	4.4	5.2	-2.3	-1.9
Ever depressed for a whole week	3.6	4.5	4.6	-2.1	-2.1
Forced expiratory volume in 1-second (FEV1)	3.5	11.7	15.2	3.9	2.9
Number of children fathered	3.5	4.0	5.2	-2.3	-1.6
Coronary Artery Disease (CAD)	3.4	4.0	4.1	-2.0	-2.0
Smoking Status	3.4	8.2	9.5	-2.6	-3.1
Forced expiratory volume in 1-second (FEV1), Best measure	3.4	10.7	12.0	3.5	3.1
Suffer from ‘nerves’	3.4	5.3	6.0	-2.5	-2.1
Exposure to tobacco smoke at home	3.3	3.7	4.1	1.8	2.0
Bipolar Disorder (2018)	3.2	5.0	6.7	2.6	1.9
HDL Cholesterol	3.2	5.3	5.8	2.2	2.4
Supplements: Glucosamine	3.2	4.2	4.6	-2.1	-1.9
Eye problems/disorders: None of the above	3.2	3.6	3.7	1.9	1.9
Mother’s age at death	3.2	4.1	6.1	2.5	1.4
Pain type(s) experienced in last month: Hip pain	3.2	4.0	4.5	-2.1	-1.9
Ever unenthusiastic/disinterested for a whole week	3.1	3.8	4.1	-1.9	-2.0
Qualifications: None of the above	3.1	6.5	7.6	-2.8	-2.3
Age at first live birth	3.1	5.5	8.6	2.9	1.6
Migraine (self-reported)	3.1	3.8	4.1	2.0	1.9
Depression (Nagel 2018)	3.0	4.5	5.6	-2.4	-1.8
Intelligence (Savage-Jansen 2018)	3.0	9.1	9.9	3.1	2.9
Blood Red Count	3.0	29.0	37.2	-4.6	-6.1
Angina	2.9	3.8	5.9	-2.4	-1.3
Length of working week for main job	2.9	3.2	3.6	1.9	1.6
Qualifications: O levels/GCSEs or equivalent	2.9	4.7	7.3	2.7	1.4
Qualifications: College or University degree	2.7	8.4	8.4	2.9	2.9
Medication: Gliclazide	2.7	3.1	3.6	1.9	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.4	3.9	-2.0	-1.7
Angina (self-reported)	2.6	3.4	5.4	-2.3	-1.1
Waist Hip Ratio (WHR)	2.5	11.2	12.7	3.6	3.1
Forced vital capacity (FVC)	2.5	9.7	12.8	3.6	2.5
Frequency of depressed mood in last 2 weeks	2.3	3.3	3.3	-1.8	-1.8
Medication: Lansoprazole	2.3	2.6	2.9	-1.5	-1.7
Family relationship satisfaction	2.3	2.9	3.3	-1.6	-1.8
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	4.7	-2.2	-0.9
Schizophrenia (2018)	2.2	4.6	5.1	2.0	2.3
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.3	4.5	-2.1	-1.5
Headache pain in last month	2.2	3.7	3.9	2.0	1.9
Forced vital capacity (FVC), Best measure	2.2	8.0	9.6	3.1	2.5
Blood Eosinophil Count	2.1	16.1	20.9	-3.4	-4.6
Fed-up feelings	2.1	3.9	6.5	-2.6	-1.1
Loneliness, isolation	2.1	2.9	3.3	-1.8	-1.6
Ever had bowel cancer screening	2.1	2.5	2.8	-1.7	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.5	5.2	1.9	2.3
Hypothyroidism (self reported)	2.0	4.5	4.5	-2.1	-2.1
Exposure to tobacco smoke outside home	2.0	2.6	3.5	1.3	1.9
Number of full brothers	2.0	2.5	2.8	-1.7	-1.5
Wheeze or whistling in the chest in last year	2.0	3.6	4.6	-1.6	-2.1
Schizophrenia (2014)	1.9	4.2	4.5	2.1	1.9
Nervous feelings	1.9	3.5	4.0	-2.0	-1.7
Qualifications: nursing, teaching	1.9	2.9	4.4	2.1	1.2
Father’s age at death	1.8	2.5	3.7	1.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	2.3	-1.5	-1.4
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	3.5	-1.0	-1.9
Verbal and Numeric Reasoning (VNR)	1.7	4.0	4.1	2.0	2.0
Mean Putamen Volume	1.7	1.9	2.6	-1.1	-1.6
Type 2 Diabetes (T2D) (2012)	1.7	2.0	2.1	-1.3	-1.5
Neuroticism	1.7	4.1	5.4	-2.3	-1.6
Serious illness, injury or assault to yourself	1.7	2.1	2.9	1.7	1.1
Time employed in main current job	1.7	2.0	2.7	1.6	1.1
Neuroticism score	1.6	3.4	5.1	-2.3	-1.3
Worrier / anxious feelings	1.6	3.0	4.1	-2.0	-1.4
Ever highly irritable/argumentative for 2 days	1.6	1.9	2.3	1.2	1.5
Commuting to job workplace: Cycle	1.6	2.0	2.6	1.6	1.2
Peak expiratory flow (PEF)	1.5	3.5	5.0	2.2	1.4
Pulse wave reflection index	1.5	1.8	2.7	-1.6	-1.0
Leg fat percentage (right)	1.5	5.3	7.0	-1.9	-2.6
Medication: Omeprazole	1.5	1.8	2.9	-0.8	-1.7
Worry (Nagel 2018)	1.4	3.0	4.3	-2.1	-1.3
Neuroticism (2016)	1.4	2.0	2.3	-1.5	-1.3
Sensitivity / hurt feelings	1.4	2.4	3.6	-1.9	-1.1
Multivitamins +/- minerals	1.4	1.7	2.0	1.2	1.4
Tense / ‘highly strung’	1.4	2.4	4.0	-2.0	-0.9
Glaucoma (self-reported)	1.4	1.7	2.0	-1.2	-1.4
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	2.2	1.5	1.1
Pack years adult smoking proportion	1.3	1.9	3.4	-1.9	-0.7
Past tobacco smoking	1.3	2.3	2.4	1.5	1.5
Had other major operations	1.3	1.6	2.6	1.6	0.8
Heart attack	1.3	1.7	2.3	-1.5	-1.0
Medication for cholesterol	1.3	2.0	2.5	1.6	1.2
Back pain experienced in last month	1.3	1.8	2.5	-1.1	-1.6
Medication: Blood pressure	1.3	2.5	3.6	-1.9	-1.2
Relative age of first facial hair	1.2	2.5	2.6	-1.5	-1.6
Medication: Atenolol	1.2	1.5	1.6	1.2	1.2
Health satisfaction	1.2	1.6	1.9	-1.4	-1.1
Medication: Seretide 50 evohaler	1.2	1.3	1.8	-1.4	-0.9
Pack years of smoking	1.2	1.8	3.2	-1.8	-0.6
Ovarian Cancer	1.1	1.5	1.9	1.0	1.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	1.8	1.3	0.8
Maternal smoking around birth	1.1	1.6	2.2	-1.5	-0.9
Medication: Paracetamol	1.1	1.9	2.6	-1.1	-1.6
Eye problems/disorders: Glaucoma	1.1	1.3	1.4	-1.2	-1.1
Leg fat percentage (left)	1.1	4.0	5.2	-1.7	-2.3
Basal cell carcinoma (self-reported)	1.1	1.3	1.5	-1.1	-1.2
Neuroticism (Nagel 2018)	1.0	2.4	4.3	-2.1	-0.7
Lung FEV1/FVC ratio	1.0	4.9	5.1	2.2	2.2
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.5	-1.2	-0.8
Diabetes (self-reported)	1.0	1.6	1.7	1.2	1.3
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	2.4	-1.0	-1.5
Medication for pain relief, constipation, heartburn	1.0	1.7	2.3	1.0	1.5
Supplements: Vitamin C	1.0	1.2	1.7	0.8	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.5	-1.2	-0.8
Osteoporosis (self-reported)	1.0	1.2	1.7	-1.3	-0.8
Guilty feelings	1.0	1.5	2.0	1.0	1.4
Supplements: Fish oil (including cod liver oil)	1.0	1.4	1.4	-1.2	-1.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	1.8	-1.3	-0.9
LDL Cholesterol	0.9	1.5	1.5	-1.2	-1.2
Height	0.9	18.3	29.5	5.4	2.7
Lung FVC	0.9	4.4	5.5	1.8	2.3
Number of treatments/medications taken	0.9	1.6	1.9	-1.4	-1.2
Supplements: Zinc	0.9	0.9	1.0	1.0	1.0
Impedance of leg (right)	0.9	4.3	5.7	-1.7	-2.4
Illnesses of mother	0.9	1.2	1.3	1.1	1.0
Pulse wave Arterial Stiffness index	0.9	1.1	1.3	1.1	0.9
Standing height	0.9	8.7	13.8	3.7	1.9
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	1.8	-1.4	-1.3
Worry too long after embarrassment	0.9	1.5	2.5	-1.6	-0.6
Comparative height size at age 10	0.9	5.2	8.9	3.0	1.2
Wears glasses or contact lenses	0.9	1.1	1.6	-1.3	-0.7
Medication: Paracetamol	0.9	1.4	2.3	-0.7	-1.5
Risk taking	0.9	1.3	2.3	0.6	1.5
Depressed Affect (Nagel 2018)	0.8	1.7	3.0	-1.7	-0.7
Alzheimer’s Disease (in mother)	0.8	0.9	1.1	1.0	0.8
Fasting Glucose	0.8	0.9	1.8	1.4	0.2
Ulcerative Colitis	0.8	1.1	1.9	-0.6	-1.4
Ever had hysterectomy (womb removed)	0.8	0.9	1.0	1.0	0.8
Vitamin and mineral supplements	0.8	1.1	1.1	-1.1	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	1.6	-1.2	-0.9
Medication: Ibuprofen	0.8	1.0	1.3	1.1	0.8
Illnesses of siblings: Diabetes	0.8	1.0	1.1	1.0	0.9
Diabetes diagnosed by doctor	0.8	1.3	1.4	1.2	1.1
Ever smoked	0.8	1.4	2.0	-0.9	-1.4
Vascular/heart problems diagnosed by doctor	0.8	2.2	3.3	1.8	1.0
Schizophrenia vs Biploar Disorder	0.7	0.9	1.0	-1.0	-0.9
Mouth/teeth dental problems	0.7	1.1	2.0	1.4	0.6
Alcohol intake versus 10 years previously	0.7	1.1	1.3	-0.9	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.9	1.7	1.3	0.0
Depression (self-reported)	0.7	0.8	1.4	0.5	1.2
Breastfed as a baby	0.7	0.9	1.1	-1.1	-0.8
Pulse wave peak to peak time	0.7	0.8	0.9	-0.9	-0.9
Smoking status: Previous	0.7	1.0	1.2	-1.1	-0.9
Breast cancer (self-reported)	0.7	0.8	1.5	-1.2	-0.4
Leg predicted mass (right)	0.7	3.6	4.6	2.1	1.6
Number of self-reported non-cancer illnesses	0.7	1.3	1.7	-0.9	-1.3
Alzheimer’s Disease (including proxy)	0.6	0.9	1.0	1.0	0.9
HbA1C	0.6	0.6	1.1	1.0	0.5
Lupus	0.6	0.9	1.0	-0.9	-1.0
Medication: Metformin	0.6	0.8	1.3	1.1	0.6
Townsend deprivation index at recruitment	0.6	0.8	1.5	-0.3	-1.2
Sitting height	0.6	4.1	4.5	1.9	2.1
Impedance of leg (left)	0.6	2.8	3.5	-1.4	-1.9
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.0	1.0	0.8
Loud music exposure frequency	0.6	0.6	1.0	-1.0	-0.4
Body fat percentage	0.6	2.4	3.5	-1.1	-1.9
Commuting to job workplace: Car/motor vehicle	0.6	0.6	1.3	-1.1	-0.0
Leg fat-free mass (right)	0.6	3.4	4.4	2.1	1.6
Average weekly red wine intake	0.6	0.9	1.3	1.1	0.7
Average weekly champagne plus white wine intake	0.6	0.8	1.0	0.8	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.0	0.5	1.0
Fractured/broken bones in last 5 years	0.6	0.8	1.0	0.7	1.0
Heart disease (siblings)	0.6	0.7	1.1	1.1	0.6
Systolic Blood Pressure	0.5	2.6	2.7	1.6	1.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	0.7	-0.8	-0.8
Current tobacco smoking	0.5	0.9	0.9	-0.9	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	1.4	1.2	1.0
High blood pressure (siblings)	0.5	0.7	1.4	-1.2	-0.2
Knee pain experienced in last month	0.5	0.7	1.0	-0.7	-1.0
Illnesses of father: None of the above (group 1)	0.5	0.6	1.0	1.0	0.3
Medication: Bendroflumethiazide	0.5	0.7	1.3	-1.1	-0.4
Rheumatoid Arthritis	0.4	0.5	0.7	-0.6	-0.8
Hand grip strength (left)	0.4	1.1	1.1	-1.1	-1.1
Chronic bronchitis/emphysema (father)	0.4	0.5	0.8	-0.9	-0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.0	-0.3	-1.0
Trunk fat-free mass	0.4	2.1	3.2	1.8	1.0
Trunk predicted mass	0.4	2.4	3.6	1.9	1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.6	-0.8	0.6
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.6	-0.6	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.6	-0.8	-0.7
Leg fat mass (right)	0.4	1.5	2.2	-0.8	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.4	1.2	0.4
Whole body fat-free mass	0.4	2.3	3.3	1.8	1.1
Whole body water mass	0.4	2.0	2.9	1.7	1.1
Medication: Lisinopril	0.4	0.5	0.5	0.7	0.7
Alcohol drinker status: Never	0.4	0.5	0.7	0.9	0.5
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.5	-0.7	-0.6
Reaction Time	0.3	0.7	1.2	-0.4	-1.1
Bipolar Disorder (2011)	0.3	0.2	0.5	0.7	0.2
Primary Biliary Cirrhosis	0.3	0.4	0.5	0.5	0.7
Blood Platelet Count	0.3	3.3	5.2	2.3	1.1
Leg fat-free mass (left)	0.3	1.8	2.7	1.6	1.0
Leg predicted mass (left)	0.3	1.7	2.6	1.6	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	0.8	0.9	0.8
Falls in the last year	0.3	0.4	0.7	-0.2	-0.8
Prospective memory result	0.3	0.4	0.4	0.5	0.7
Neck or shoulder pain in last month	0.3	0.4	0.7	0.4	0.9
Whole body fat mass	0.3	1.1	1.8	-0.6	-1.3
Long-standing illness, disability or infirmity	0.3	0.5	0.9	0.1	-1.0
Smoking status: Current	0.3	0.4	0.4	-0.6	-0.6
Financial situation satisfaction	0.3	0.4	0.4	-0.6	-0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.6	-0.8	-0.2
Number of operations (self-reported)	0.3	0.4	0.8	0.1	-0.9
Irritability	0.3	0.4	0.7	-0.8	0.5
Alcohol drinker status: Previous	0.3	0.3	0.7	-0.8	0.0
Leg fat mass (left)	0.3	1.0	1.6	-0.6	-1.3
Alzheimer’s Disease (in father)	0.2	0.2	0.3	-0.4	-0.6
Breast Cancer	0.2	0.5	0.8	0.9	0.4
Prostate Cancer	0.2	0.2	0.3	-0.4	0.6
Cardiovascular Disease	0.2	0.6	1.1	0.4	1.0
Medication for hormone replacement therapy	0.2	0.3	0.4	0.7	0.3
Severe depression (siblings)	0.2	0.2	0.3	0.5	0.4
Trunk fat percentage	0.2	0.9	1.6	-0.5	-1.3
Hand grip strength (right)	0.2	0.4	0.9	-0.1	-0.9
Relative age voice broke	0.2	0.3	0.3	-0.5	-0.6
High blood pressure	0.2	0.6	1.1	-1.0	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.6	0.0	-0.8
Medication: Levothyroxine sodium	0.2	0.3	0.5	-0.4	-0.7
Had menopause	0.2	0.2	0.3	0.4	0.5
Arm fat percentage (right)	0.2	0.8	1.3	-0.5	-1.1
Hair/balding pattern: Pattern 3	0.2	0.3	0.3	0.5	0.5
Blood clot in the leg (DVT)	0.2	0.3	0.4	-0.6	-0.5
Medication: Amlodipine	0.2	0.3	0.6	0.1	0.8
Birth weight	0.2	0.4	0.8	-0.1	-0.9
Mean time to correctly identify matches	0.2	0.3	0.6	-0.2	-0.7
Alcohol intake frequency.	0.2	0.6	0.7	-0.7	-0.8
Overall health rating	0.2	0.5	0.8	-0.9	-0.3
Had major operations	0.2	0.2	0.4	0.6	-0.1
Medication: Aspirin	0.2	0.2	0.5	-0.7	0.0
Arm fat percentage (left)	0.2	1.0	1.5	-0.6	-1.2
Medication: Aspirin	0.2	0.2	0.4	-0.7	-0.0
Hearing aid user	0.2	0.2	0.3	0.2	0.5
Medication: Atorvastatin	0.2	0.3	0.5	0.2	0.7
Basal metabolic rate	0.2	1.3	2.1	1.4	0.7
Diastolic blood pressure, automated reading	0.2	0.8	0.9	0.9	0.8
Myopia	0.2	0.4	0.5	-0.5	-0.7
Pain experienced in last month	0.2	0.3	0.6	-0.2	-0.8
Supplements: Calcium	0.2	0.2	0.4	0.6	0.2
Arm predicted mass (left)	0.2	0.8	1.3	1.1	0.6
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.0	-0.6
Hair Pigment	0.1	4.2	6.9	2.6	1.2
Systolic blood pressure, automated reading	0.1	0.2	0.2	0.4	0.4
Medication: Co-codamol	0.1	0.1	0.1	-0.3	-0.2
Diabetes (mother)	0.1	0.2	0.2	0.5	0.3
Age when periods started (menarche)	0.1	0.3	0.3	0.5	0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.1	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.2	0.4
Body mass index (BMI)	0.1	0.6	0.7	-0.7	-0.8
Trunk fat mass	0.1	0.3	0.5	0.2	-0.7
Waist circumference	0.1	0.2	0.4	0.6	0.1
Alcohol usually taken with meals	0.1	0.2	0.3	0.2	0.5
Pain all over the body in last month	0.1	0.1	0.2	-0.4	-0.3
Weight	0.1	0.5	1.1	1.0	0.2
Impedance of arm (right)	0.1	0.4	0.7	0.8	-0.4
Hip circumference	0.1	0.3	0.6	-0.1	-0.8
Noisy workplace	0.1	0.1	0.1	-0.3	0.2
Medication: Cholesterol lowering	0.1	0.2	0.3	0.1	0.6
Lung cancer (father)	0.1	0.1	0.1	-0.3	-0.3
Impedance of arm (left)	0.1	0.3	0.5	0.7	-0.4
Arm fat mass (right)	0.1	0.6	0.9	-0.4	-1.0
Gout (self-reported)	0.1	0.2	0.4	0.0	0.6
Arm fat-free mass (right)	0.1	0.5	0.8	0.9	0.4
Comparative body size at age 10	0.1	0.4	0.7	0.9	0.0
Medication: Allopurinol	0.1	0.2	0.2	-0.4	-0.4
Arm predicted mass (right)	0.1	0.5	0.7	0.8	0.5
Chest pain or discomfort	0.1	0.1	0.1	0.3	-0.3
Mood swings	0.1	0.2	0.4	-0.6	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.1	-0.4	0.2
Osteoarthritis (self-reported)	0.1	0.1	0.2	0.4	0.3
Arm fat mass (left)	0.1	0.4	0.8	-0.2	-0.9
Ever taken oral contraceptive pill	0.1	0.1	0.1	0.3	0.3
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.4	-0.2
Arm fat-free mass (left)	0.1	0.7	1.2	1.1	0.6
Unable to work because of sickness or disability	0.1	0.2	0.3	0.5	-0.3
Cholesterol lowering medication	0.1	0.2	0.2	-0.4	-0.4
Impedance of whole body	0.1	0.6	1.1	-0.4	-1.1
Crohns Disease (2017)	0.0	0.1	0.1	-0.3	-0.3
Irritable Bowel Disease (IBD)	0.0	0.0	0.1	0.2	-0.3
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.1	0.1
Crohns Disease (2012)	0.0	0.0	0.0	-0.1	-0.1
Blood White Count	0.0	0.4	0.6	0.4	-0.8
Heel T-Score	0.0	0.2	0.3	0.6	0.3
BMI	0.0	0.2	0.5	0.1	-0.7
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.0	0.1	-0.1
Tanning	0.0	0.1	0.1	0.3	0.2
Hearing difficulty/problems: Yes	0.0	0.0	0.0	-0.0	0.1
Diabetes (father)	0.0	0.1	0.1	-0.0	-0.3
Average weekly fortified wine intake	0.0	0.1	0.1	0.3	-0.2
Taking other prescription medications	0.0	0.0	0.0	-0.1	-0.1
High blood pressure (mother)	0.0	0.0	0.0	0.0	-0.0
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	-0.2	0.1
Financial difficulties in last 2 years	0.0	0.0	0.0	0.2	0.2
Medication: Simvastatin	0.0	0.1	0.1	-0.2	-0.3
Illnesses of siblings	0.0	0.0	0.1	0.3	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	0.3	0.3
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	0.3	0.2
Birth weight of first child	0.0	0.1	0.1	-0.1	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	0.2	0.1
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.0	-0.1	0.1
Medication: Blood pressure	0.0	0.1	0.1	0.2	0.3
Number of full sisters	0.0	0.0	0.0	0.1	0.2
Age at last live birth	0.0	0.0	0.0	0.1	-0.2
Leg pain on walking	0.0	0.0	0.0	0.0	-0.0
Hypertension (Self-reported)	0.0	0.1	0.1	-0.3	0.1
Illnesses of father: Heart disease	0.0	0.0	0.1	-0.3	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	0.3	-0.0
High cholesterol (Self-reported)	0.0	0.0	0.1	-0.0	-0.3
Average weekly beer plus cider intake	0.0	0.1	0.1	0.2	0.3

Hub : Genes

CDC25C

Models

Trait associations