TWAS hub - CDH9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.122	0.0340	4.6e-10	0.099	0.098	0.107	0.101	0.099	4.7e-12	5.4e-12	5.8e-13	2.9e-12	4.6e-12
2	ROSMAP	Brain Pre-frontal Cortex	0.164	0.0316	0.0e+00	0.241	0.127	0.236	0.091	0.084	1.4e-30	4.9e-16	5.9e-30	8.9e-12	6.6e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Qualifications: None of the above	10.8	23.2	26.8	5.2	-4.4
Depressed Affect (Nagel 2018)	9.6	20.2	21.0	-4.6	4.4
Myopia	8.7	12.7	15.1	-3.2	3.9
Depression (Nagel 2018)	8.3	12.5	14.9	-3.2	3.9
Commuting to job workplace: Cycle	7.9	9.5	11.2	-3.3	2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	7.8	11.9	13.0	-3.6	3.3
Fluid intelligence score	7.7	15.9	18.0	-4.2	3.7
Qualifications: A levels/AS levels or equivalent	7.1	15.7	18.6	-4.3	3.6
Suffer from ‘nerves’	7.1	11.2	12.7	-3.1	3.6
Neuroticism (Nagel 2018)	6.9	16.3	16.5	-4.0	4.1
Wears glasses or contact lenses	6.7	7.8	8.3	-2.7	2.9
Multivitamins +/- minerals	6.1	7.7	9.8	-2.4	3.1
Neuroticism score	6.1	12.6	13.1	-3.5	3.6
Frequency of depressed mood in last 2 weeks	6.0	8.4	8.5	-2.9	2.9
Qualifications: College or University degree	5.9	18.5	24.9	-5.0	3.5
Number of incorrect matches in round	5.8	9.6	12.0	3.5	-2.7
Nervous feelings	5.7	10.7	10.7	-3.3	3.3
High blood pressure (siblings)	5.7	8.2	9.5	2.6	-3.1
Qualifications: nursing, teaching	5.7	8.8	8.9	-3.0	2.9
Neuroticism	5.6	13.4	14.2	-3.6	3.8
Vitamin and mineral supplements	5.6	7.6	8.2	2.6	-2.9
Supplements: Zinc	5.4	5.9	6.6	-2.6	2.3
Qualifications: O levels/GCSEs or equivalent	5.3	8.4	9.5	-3.1	2.7
Worry too long after embarrassment	5.3	8.9	10.8	-3.3	2.6
Neuroticism (2016)	5.2	7.6	7.8	-2.7	2.8
Prospective memory result	5.2	6.4	7.8	2.8	-2.2
Miserableness	5.2	8.9	10.0	-3.2	2.8
Medication: Lisinopril	5.2	6.7	7.3	2.7	-2.5
Verbal and Numeric Reasoning (VNR)	5.1	12.3	15.9	-4.0	2.9
Illnesses of siblings	5.0	7.0	8.6	-2.3	2.9
Heart attack	4.9	6.2	7.2	-2.3	2.7
Intelligence (Savage-Jansen 2018)	4.5	13.7	18.7	-4.3	2.9
Guilty feelings	4.2	6.3	8.0	-2.2	2.8
Medication: Ibuprofen (e.g. Nurofen)	4.1	5.3	7.2	-2.7	1.8
Major Depression (MDD)	4.0	4.8	6.3	-1.8	2.5
Alcohol usually taken with meals	4.0	6.5	6.7	-2.5	2.6
Happiness	4.0	4.8	4.8	-2.2	2.2
Eye problems/disorders: Cataract	4.0	4.6	4.7	-2.2	2.1
Commuting to job workplace: Public transport	3.9	4.7	5.3	-2.3	2.0
Fed-up feelings	3.8	7.0	8.0	-2.8	2.4
Alcohol intake versus 10 years previously	3.8	5.7	6.3	-2.3	2.5
Medication: Lansoprazole	3.7	4.2	5.5	2.3	-1.7
Heart attack/myocardial infarction (self-reported)	3.7	4.8	5.5	-2.0	2.3
Mouth/teeth dental problems: Dentures	3.5	5.9	7.7	2.8	-2.0
HDL Cholesterol	3.4	5.7	7.7	1.9	-2.8
Systolic blood pressure, automated reading	3.4	9.7	12.2	3.5	-2.7
Supplements: Glucosamine	3.4	4.4	4.7	-2.0	2.2
Leg pain on walking	3.4	4.3	5.8	2.4	-1.7
Mean Putamen Volume	3.3	3.8	5.2	-2.3	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.2	3.8	5.8	2.4	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	3.2	3.4	5.0	-1.3	2.2
Medication: Paracetamol	3.1	5.1	6.1	-2.0	2.5
Hearing difficulty/problems with background noise	3.0	4.8	5.5	-2.3	2.0
Health satisfaction	3.0	3.9	4.8	-1.7	2.2
Financial difficulties in last 2 years	2.9	3.9	5.6	-2.4	1.5
HbA1C	2.7	3.0	4.8	-2.2	1.1
Systolic Blood Pressure	2.7	13.6	14.0	3.7	-3.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.7	3.2	3.6	1.7	-1.9
Osteoarthritis (self-reported)	2.7	3.5	3.6	1.8	-1.9
Deep venous thrombosis (DVT) (self-reported)	2.7	3.5	5.8	2.4	-1.1
Average weekly spirits intake	2.6	3.2	3.3	1.8	-1.8
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.3	5.4	-1.8	2.3
Knee pain experienced in last month	2.6	4.0	5.2	2.3	-1.7
Worry (Nagel 2018)	2.5	5.3	5.4	-2.3	2.3
Blood clot in the leg (DVT)	2.5	3.2	5.4	2.3	-1.0
Medication for pain relief, constipation, heartburn	2.4	4.1	5.1	2.2	-1.8
Ever taken oral contraceptive pill	2.4	2.7	3.2	-1.5	1.8
Rheumatoid Arthritis	2.3	3.2	3.8	1.9	-1.6
Other serious medical condition/disability diagnosed by doctor	2.3	3.0	4.2	-1.4	2.0
Worrier / anxious feelings	2.3	4.4	4.4	-2.1	2.1
Medication: Ibuprofen	2.3	2.7	3.5	-1.9	1.4
Average weekly champagne plus white wine intake	2.3	3.2	3.6	-1.6	1.9
Bipolar Disorder (2018)	2.2	3.4	4.2	-1.6	2.1
Had menopause	2.2	2.8	3.0	1.7	-1.6
Had other major operations	2.2	2.6	5.1	-0.4	2.3
Loneliness, isolation	2.2	3.0	3.2	-1.7	1.8
Back pain experienced in last month	2.2	3.2	5.5	2.3	-1.0
Illnesses of siblings: Diabetes	2.1	2.6	2.7	1.6	-1.6
Mineral and other dietary supplements	2.1	2.8	3.6	1.9	-1.4
Medication: Co-codamol	2.0	2.3	4.1	2.0	-0.8
Heart disease (mother)	2.0	2.4	2.6	-1.5	1.6
Had major operations	2.0	2.4	3.3	-1.2	1.8
Average weekly beer plus cider intake	2.0	2.8	3.2	1.8	-1.6
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	2.4	-1.4	1.6
Age at last live birth	1.9	2.7	4.0	-2.0	1.2
Illness, injury, bereavement, stress in last 2 years	1.9	2.3	2.5	1.4	-1.6
Mood swings	1.9	3.4	3.8	-1.7	1.9
Ever depressed for a whole week	1.9	2.3	2.5	-1.5	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	2.9	-1.4	1.7
Medication: Bendroflumethiazide	1.8	2.7	3.0	1.7	-1.6
Ovarian Cancer	1.7	2.3	3.5	-1.1	1.9
Migraine (self-reported)	1.7	2.1	3.7	-1.9	0.7
Hypertension (Self-reported)	1.7	4.7	5.3	2.3	-2.0
Fasting Glucose	1.6	1.9	3.1	-0.8	1.8
Wheeze or whistling in the chest in last year	1.6	2.9	4.2	2.1	-1.2
Medication: Simvastatin	1.5	2.2	2.9	1.2	-1.7
Impedance of arm (left)	1.5	7.2	9.9	-3.1	2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	2.0	-1.4	1.2
Medication: Allopurinol	1.5	2.0	2.1	1.5	-1.4
Illnesses of father: None of the above (group 1)	1.5	1.9	3.2	-1.8	0.8
Ever had hysterectomy (womb removed)	1.4	1.6	2.3	1.5	-0.9
Number of live births	1.4	1.9	2.1	1.3	-1.4
Length of working week for main job	1.4	1.6	2.3	-1.5	0.9
Ever highly irritable/argumentative for 2 days	1.4	1.7	1.7	1.3	-1.3
Emphysema/chronic bronchitis	1.4	1.5	2.2	1.5	-1.0
Handedness (chirality/laterality): Left-handed	1.4	1.6	2.1	1.0	-1.5
Mouth/teeth dental problems: Mouth ulcers	1.4	2.3	2.8	-1.3	1.7
Diastolic blood pressure, automated reading	1.4	4.3	6.2	2.5	-1.5
Chronotype (morning person)	1.3	3.0	3.1	1.8	-1.7
Hand grip strength (right)	1.3	3.6	4.1	1.8	-2.0
High blood pressure	1.3	3.6	4.6	2.1	-1.6
Chronic bronchitis/emphysema (father)	1.3	1.5	2.1	1.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	4.1	1.2	-2.0
Number of self-reported non-cancer illnesses	1.3	2.3	2.9	1.7	-1.3
Illnesses of father: High blood pressure	1.3	1.6	2.9	1.7	-0.6
Asthma	1.2	2.4	3.1	1.7	-1.3
Depression (self-reported)	1.2	1.4	1.8	1.3	-1.0
LDL Cholesterol	1.1	1.7	1.8	1.2	-1.3
Hand grip strength (left)	1.1	2.9	3.0	1.7	-1.7
Average weekly fortified wine intake	1.1	1.3	1.5	-1.1	1.2
Impedance of arm (right)	1.1	5.1	7.9	-2.8	1.5
Medication: Ventolin 100micrograms inhaler	1.1	1.4	1.7	1.0	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	1.8	-1.3	1.1
Alcohol intake frequency.	1.1	2.5	3.1	-1.8	1.3
Medication: Blood pressure	1.1	2.1	2.4	1.4	-1.6
Alcohol drinker status: Previous	1.1	1.2	1.8	-1.3	0.8
Impedance of whole body	1.1	5.7	7.4	-2.7	2.0
Triglycerides	1.0	1.6	1.7	-1.2	1.3
Stomach or abdominal pain in last month	1.0	1.2	1.7	-0.8	1.3
Neck or shoulder pain in last month	1.0	1.4	2.7	0.4	1.6
Asthma (self-reported)	1.0	2.0	2.5	1.6	-1.2
Alzheimer’s Disease (in mother)	0.9	1.0	1.5	-0.8	1.2
Cardiovascular Disease	0.9	2.9	3.1	1.8	-1.6
Hypothyroidism (self reported)	0.9	2.0	2.6	-1.6	1.2
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.6	-0.8	1.3
Pulse wave peak to peak time	0.9	1.0	1.7	1.3	-0.6
Mother’s age at death	0.9	1.1	1.4	-1.2	0.9
Supplements: Fish oil (including cod liver oil)	0.9	1.1	1.2	-1.1	1.0
Fractured/broken bones in last 5 years	0.9	1.1	1.3	1.2	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	1.5	-1.0	1.2
Allergy	0.8	1.9	2.4	-1.6	1.2
Pulse wave Arterial Stiffness index	0.8	1.0	1.6	-1.3	0.5
Headache pain in last month	0.8	1.3	1.9	-1.4	0.9
Family relationship satisfaction	0.8	1.0	1.1	-1.1	1.0
Vascular/heart problems diagnosed by doctor	0.8	2.1	2.9	-1.7	1.1
Arm predicted mass (left)	0.8	4.1	5.6	2.4	-1.6
Birth weight of first child	0.7	1.3	1.7	1.3	-1.0
Number of full brothers	0.7	0.8	0.9	-0.9	0.9
Supplements: Vitamin C	0.7	0.9	1.2	-1.1	0.8
Arm fat-free mass (left)	0.7	3.3	4.8	2.2	-1.4
Reaction Time	0.6	1.1	1.3	0.9	-1.2
Lung FVC	0.6	3.2	3.8	1.6	-1.9
Medication for hormone replacement therapy	0.6	0.7	1.0	-0.6	1.0
Impedance of leg (right)	0.6	2.7	3.4	-1.8	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	1.8	-0.9	1.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.1	-0.5	1.0
Hayfever, allergic rhinitis or eczema	0.6	1.2	1.6	0.9	-1.2
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.1	0.6	-1.1
Impedance of leg (left)	0.6	2.7	3.2	-1.8	1.5
Pulse wave reflection index	0.6	0.7	1.2	-1.1	0.4
Arm fat-free mass (right)	0.6	2.8	4.2	2.0	-1.2
Long-standing illness, disability or infirmity	0.6	0.9	1.8	1.3	0.2
Financial situation satisfaction	0.6	0.8	1.4	-0.4	1.2
Basal cell carcinoma (self-reported)	0.6	0.8	1.4	-0.3	1.2
Allergy or Eczema	0.5	1.2	1.8	0.8	-1.3
Angina	0.5	0.6	0.8	-0.9	0.7
Current tobacco smoking	0.5	0.9	1.6	-0.4	1.3
Relative age voice broke	0.5	0.8	1.3	-1.1	0.5
Taking other prescription medications	0.5	0.8	0.8	0.9	-0.9
Age when periods started (menarche)	0.5	1.2	2.4	0.1	-1.6
Trunk fat-free mass	0.5	2.7	3.6	1.9	-1.3
Illnesses of mother	0.5	0.6	1.3	-0.0	-1.1
Illnesses of father: Heart disease	0.5	0.7	1.3	1.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.5	-0.7	1.2
Medication: Paracetamol	0.5	0.8	1.1	-0.7	1.1
Cholesterol lowering medication	0.5	0.8	1.0	1.0	-0.7
Ulcerative Colitis (UC)	0.4	0.7	1.3	1.1	-0.4
Schizophrenia (2014)	0.4	0.9	1.2	1.1	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.5	0.7	-0.6
Qualifications: CSEs or equivalent	0.4	0.6	1.1	1.1	0.1
Serious illness, injury or assault to yourself	0.4	0.5	0.7	-0.6	0.8
Pain all over the body in last month	0.4	0.5	0.5	0.6	-0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	1.5	0.9	-1.2
Medication: Cholesterol lowering	0.4	0.6	0.8	-0.6	0.9
Arm fat mass (right)	0.4	1.7	2.5	1.6	-0.9
Trunk predicted mass	0.4	2.4	3.2	1.8	-1.2
Exposure to tobacco smoke at home	0.4	0.5	0.9	-0.2	1.0
Glaucoma (self-reported)	0.4	0.4	0.6	0.5	-0.8
Gout (self-reported)	0.4	0.5	0.7	0.9	-0.5
Age at first live birth	0.4	0.7	1.3	-1.1	0.1
Shortness of breath walking on level ground	0.4	0.5	0.8	0.9	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.7	-0.4	0.8
Arm predicted mass (right)	0.4	2.2	3.5	1.9	-1.0
Number of full sisters	0.4	0.5	0.8	-0.9	0.4
Medication: Aspirin	0.4	0.5	0.6	-0.8	0.7
Whole body fat-free mass	0.4	2.3	3.2	1.8	-1.2
Whole body water mass	0.4	2.5	3.4	1.8	-1.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.5	0.7	0.7
Basal metabolic rate	0.4	2.2	3.2	1.8	-1.1
Number of operations (self-reported)	0.4	0.6	0.8	0.9	0.6
Supplements: Calcium	0.4	0.5	0.6	-0.5	0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.6	0.3	-0.8
Crohns Disease (2017)	0.3	0.7	1.5	1.2	-0.2
Irritable Bowel Disease (IBD)	0.3	0.8	1.5	1.2	-0.2
Age at First Birth	0.3	0.4	0.8	0.2	-0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.6	-0.8	0.3
Ulcerative Colitis	0.3	0.5	0.5	0.7	-0.7
Blood White Count	0.3	2.1	3.3	-0.9	1.8
Respiratory disease	0.3	0.7	1.3	1.2	-0.3
Hair Pigment	0.3	7.3	8.0	2.8	-2.6
Sensitivity / hurt feelings	0.3	0.5	0.8	-0.4	0.9
Relative age of first facial hair	0.3	0.7	1.3	-1.1	0.2
Severe depression (siblings)	0.3	0.4	0.4	-0.6	0.7
Leg fat-free mass (left)	0.3	1.8	2.6	1.6	-1.0
Townsend deprivation index at recruitment	0.3	0.4	0.9	0.9	-0.1
Maternal smoking around birth	0.3	0.4	0.5	-0.7	0.5
Body mass index (BMI)	0.3	1.4	2.3	1.5	-0.7
Leg predicted mass (left)	0.3	1.5	2.3	1.5	-0.9
Forced vital capacity (FVC)	0.3	1.1	1.3	1.0	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	0.9	-0.7	0.9
Weight	0.3	1.3	2.2	1.5	-0.7
Father’s age at death	0.3	0.4	0.5	0.5	-0.7
Falls in the last year	0.3	0.5	0.9	0.3	0.9
Breastfed as a baby	0.3	0.3	0.6	0.3	-0.8
Loud music exposure frequency	0.3	0.3	0.5	-0.4	0.7
Medication: Seretide 50 evohaler	0.3	0.4	0.6	0.8	-0.4
Mean time to correctly identify matches	0.3	0.5	0.6	0.6	-0.8
Overall health rating	0.3	0.6	1.1	-0.1	1.1
Chest pain or discomfort	0.3	0.4	0.7	-0.3	0.8
Leg fat-free mass (right)	0.3	1.6	2.3	1.5	-1.0
Leg predicted mass (right)	0.3	1.7	2.4	1.6	-1.0
Risk taking	0.3	0.5	0.7	-0.9	0.5
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.5	-0.3	0.7
Leg fat mass (left)	0.3	1.0	1.9	1.4	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	0.9	-0.4	0.9
Schizophrenia (2018)	0.2	0.4	0.6	0.7	-0.5
Primary Biliary Cirrhosis	0.2	0.2	0.4	0.2	0.6
Blood Red Count	0.2	1.8	2.2	1.5	-1.1
Lung FEV1/FVC ratio	0.2	0.9	1.8	0.4	-1.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.6	0.8	0.1
Diabetes (father)	0.2	0.3	0.4	0.6	-0.4
Past tobacco smoking	0.2	0.4	0.6	0.4	-0.8
Mouth/teeth dental problems	0.2	0.4	0.7	0.1	-0.8
Angina (self-reported)	0.2	0.3	0.4	-0.6	0.4
Medication: Omeprazole	0.2	0.3	0.5	-0.7	0.2
Leg fat mass (right)	0.2	0.8	1.5	1.2	-0.3
Commuting to job workplace: Walk	0.2	0.2	0.4	0.6	0.0
Medication: Aspirin	0.2	0.3	0.3	-0.6	0.5
Medication: Gliclazide	0.2	0.2	0.2	0.5	0.4
Smoking status: Current	0.2	0.3	0.6	0.0	0.8
Arm fat mass (left)	0.2	0.9	1.5	1.2	-0.5
High cholesterol (Self-reported)	0.2	0.4	0.6	0.3	-0.8
Medication: Atorvastatin	0.2	0.3	0.4	-0.4	0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	-0.7	0.1
Pack years of smoking	0.2	0.3	0.3	0.5	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.4	-0.2
Alzheimer’s Disease (including proxy)	0.1	0.2	0.2	-0.4	0.5
Breast Cancer	0.1	0.2	0.3	-0.3	0.6
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	0.6	0.1
Crohns Disease (2012)	0.1	0.2	0.3	0.6	0.1
Blood Platelet Count	0.1	1.1	1.5	-0.9	1.2
Height	0.1	1.3	2.0	0.8	-1.4
Smoking Status	0.1	0.2	0.3	0.6	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	0.1	0.4
Tanning	0.1	1.8	1.9	-1.3	1.4
Number of treatments/medications taken	0.1	0.2	0.3	0.5	-0.2
Hearing difficulty/problems: Yes	0.1	0.2	0.3	0.5	-0.2
Medication: Metformin	0.1	0.2	0.4	0.6	-0.0
Diabetes (mother)	0.1	0.1	0.2	0.4	0.0
Pack years adult smoking proportion	0.1	0.2	0.2	0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.3	0.5	-0.2
Medication: Atenolol	0.1	0.1	0.2	0.2	-0.4
Sitting height	0.1	0.6	0.7	0.7	-0.9
Trunk fat mass	0.1	0.3	0.6	0.7	-0.3
Waist circumference	0.1	0.4	0.8	0.9	0.0
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	0.0	0.4
Diabetes (self-reported)	0.1	0.2	0.3	0.6	0.1
Hip circumference	0.1	0.3	0.5	0.7	-0.3
Time employed in main current job	0.1	0.1	0.2	-0.1	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	0.2	-0.3
Lung cancer (father)	0.1	0.1	0.1	0.3	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	0.2	-0.6
Peak expiratory flow (PEF)	0.1	0.2	0.3	0.6	-0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	-0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.6	-0.0
Medication: Amlodipine	0.1	0.2	0.4	0.6	-0.1
Birth weight	0.1	0.3	0.3	0.6	-0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	0.2	0.3
Forced vital capacity (FVC), Best measure	0.1	0.4	0.6	0.5	-0.7
Exposure to tobacco smoke outside home	0.1	0.2	0.2	0.4	-0.4
Comparative body size at age 10	0.1	0.2	0.2	-0.3	0.5
Number of children fathered	0.1	0.1	0.1	-0.4	0.3
Whole body fat mass	0.1	0.5	0.9	1.0	-0.4
Comparative height size at age 10	0.1	0.3	0.7	0.1	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.2	0.5	0.3
Ever had bowel cancer screening	0.1	0.1	0.2	-0.4	0.2
Diabetes diagnosed by doctor	0.1	0.2	0.3	0.1	0.5
Medication for cholesterol	0.1	0.1	0.1	0.3	-0.2
Breast cancer (self-reported)	0.1	0.1	0.1	0.2	0.3
Hearing aid user	0.1	0.2	0.3	0.1	0.6
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.2	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.2	-0.4
Alcohol drinker status: Never	0.1	0.2	0.2	-0.4	-0.4
Ever smoked	0.1	0.2	0.3	-0.2	0.6
Leg fat percentage (left)	0.1	0.3	0.5	0.7	0.1
Irritability	0.1	0.2	0.3	-0.5	0.3
Age started oral contraceptive pill	0.1	0.1	0.1	0.4	0.1
Pain experienced in last month	0.1	0.1	0.1	-0.3	-0.3
Heart disease (siblings)	0.1	0.1	0.2	-0.2	-0.4
Prostate Cancer	0.0	0.1	0.1	0.3	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.1	0.2
Coronary Artery Disease (CAD)	0.0	0.0	0.1	0.3	0.0
Lupus	0.0	0.1	0.1	-0.3	-0.1
Blood Eosinophil Count	0.0	0.1	0.1	0.2	0.3
Heel T-Score	0.0	0.3	0.5	0.2	0.7
BMI	0.0	0.1	0.2	0.4	-0.3
Waist Hip Ratio (WHR)	0.0	0.1	0.2	0.2	0.5
Trunk fat percentage	0.0	0.0	0.1	0.0	0.2
Medication: Levothyroxine sodium	0.0	0.1	0.2	-0.4	0.0
High blood pressure (mother)	0.0	0.0	0.1	0.3	0.0
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	-0.1	-0.3
Medication: Ramipril	0.0	0.1	0.1	0.2	-0.2
Arm fat percentage (right)	0.0	0.1	0.3	0.5	-0.1
Pulse rate	0.0	0.0	0.0	0.1	0.1
Noisy workplace	0.0	0.0	0.0	0.2	-0.0
Standing height	0.0	0.1	0.1	0.3	-0.3
Tense / ‘highly strung’	0.0	0.1	0.2	0.4	-0.0
Hair/balding pattern: Pattern 4	0.0	0.0	0.1	-0.0	0.3
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	-0.3	-0.2
Body fat percentage	0.0	0.1	0.1	0.1	0.3
Leg fat percentage (right)	0.0	0.2	0.3	0.6	0.2
Eye problems/disorders: None of the above	0.0	0.0	0.0	-0.1	-0.1
Medication: Blood pressure	0.0	0.0	0.0	0.1	0.1
Pulse rate, automated reading	0.0	0.1	0.2	-0.2	0.5
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	-0.0	0.3
Smoking status: Previous	0.0	0.1	0.1	0.1	0.3
Arm fat percentage (left)	0.0	0.1	0.1	0.3	0.2
Average weekly red wine intake	0.0	0.0	0.1	0.1	0.2
Friendships satisfaction	0.0	0.1	0.1	-0.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	0.1	-0.0
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.1	-0.2
Unable to work because of sickness or disability	0.0	0.0	0.1	0.3	0.1

Hub : Genes

CDH9

Models

Trait associations