Hub : Genes

CDK5RAP2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0760	0.0220	2.1e-06	0.071	0.022	0.058	0.059	0.059	5.2e-09	1.0e-03	1.3e-07	9.4e-08	1.1e-07
2	GTEx	Artery Aorta	0.2730	0.0760	5.1e-04	0.123	NA	0.120	NA	0.113	2.9e-07	NA	3.8e-07	NA	8.4e-07
3	GTEx	Artery Tibial	0.0699	0.0307	9.8e-03	0.005	NA	0.036	NA	0.035	1.1e-01	NA	7.8e-04	NA	8.3e-04
4	GTEx	Esophagus Muscularis	0.0980	0.0400	3.1e-03	0.017	NA	0.010	NA	0.036	3.1e-02	NA	7.5e-02	NA	3.0e-03
5	GTEx	Stomach	0.2930	0.0880	2.9e-04	0.079	NA	0.013	NA	0.049	1.3e-04	NA	7.7e-02	NA	2.1e-03
6	GTEx	Testis	0.3140	0.0840	9.4e-05	0.146	NA	0.054	NA	0.148	5.0e-07	NA	2.0e-03	NA	4.3e-07
7	YFS	Blood	0.0386	0.0111	7.2e-07	0.031	0.026	0.037	0.032	0.038	1.8e-10	5.4e-09	2.6e-12	8.4e-11	2.2e-12
8	TCGA	Breast Invasive Carcinoma	0.0201	0.0104	6.6e-04	0.026	0.008	0.024	NA	0.023	3.6e-06	8.4e-03	8.5e-06	NA	1.0e-05
9	TCGA	Colon Adenocarcinoma	0.0790	0.0400	5.2e-03	-0.003	0.039	-0.003	NA	-0.005	5.3e-01	2.6e-03	5.8e-01	NA	9.6e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.7	1.7	0.5	-1.0	-0.9	-0.2	1.3	0.6	0.9	1.2	-0.3
Bipolar Disorder or Schizophrenia	0.4	0.9	3.0	1.4	-0.3	0.1	0.3	1.7	0.4	0.4	1.5	-0.3
Depressed Affect (Nagel 2018)	0.1	0.2	0.6	0.3	0.0	0.5	0.8	0.7	0.2	0.2	0.6	0.4
Depression (Nagel 2018)	0.5	0.8	1.5	-1.2	0.8	0.3	0.9	-0.9	-0.9	-0.9	-1.0	-0.9
Intelligence (Savage-Jansen 2018)	0.1	0.4	2.1	0.6	-1.4	0.3	-0.6	0.3	0.4	0.3	0.5	0.5
Neuroticism (Nagel 2018)	0.1	0.2	0.5	-0.3	0.2	0.7	0.7	0.5	-0.2	-0.5	0.4	0.4
Schizophrenia (2018)	0.3	0.6	1.9	1.4	0.3	0.9	0.5	1.2	-0.0	-0.2	1.0	-0.1
Schizophrenia vs Biploar Disorder	0.6	0.8	1.9	0.0	0.6	1.0	0.6	-1.1	-0.7	-1.4	-0.9	-0.7
Worry (Nagel 2018)	0.3	0.7	2.3	-0.6	-0.0	1.3	1.2	0.1	-0.9	-1.5	0.1	0.4
Alzheimer’s Disease (in mother)	0.3	0.4	2.5	-1.6	0.7	-0.2	-0.1	-0.4	0.3	-0.2	0.0	-0.3
Alzheimer’s Disease (in father)	2.5	2.7	5.6	-2.4	-0.6	-1.5	-1.3	-1.9	0.8	0.5	-2.3	-2.0
Alzheimer’s Disease (including proxy)	0.9	1.3	5.9	-2.4	0.3	-0.8	-0.8	-1.1	0.7	0.1	-1.0	-1.4
Crohns Disease (2017)	0.5	1.2	3.0	0.9	-1.7	1.4	1.1	0.4	-1.3	-1.2	0.4	0.4
Irritable Bowel Disease (IBD)	0.4	0.8	4.8	0.0	-2.2	0.9	-0.3	-0.0	-0.8	-0.9	0.2	-0.6
Ulcerative Colitis (UC)	0.5	0.9	2.3	0.1	-1.5	1.2	-0.3	0.7	-1.1	-1.1	1.0	-0.4
Major Depression (MDD)	0.3	0.4	1.9	0.5	-0.5	-0.2	0.7	-0.1	0.4	0.3	-0.4	-1.4
Reaction Time	1.8	3.4	8.8	-0.3	-1.5	-2.0	-2.5	-0.3	2.5	3.0	-0.2	-1.7
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.9	0.9	-0.8	0.2	0.0	0.8	0.3	0.1	0.9	0.5
Breast Cancer	0.2	0.6	2.0	-0.7	-1.4	0.5	0.6	-0.4	-0.4	-0.6	-0.4	-1.1
Ovarian Cancer	3.0	4.0	9.2	0.7	-1.5	2.8	2.6	0.7	-3.0	-2.7	0.4	1.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.2	0.2	0.6	0.8	0.4	0.3	-0.3	0.5	0.6	0.2	0.6	0.3
Bipolar Disorder (2011)	1.1	1.1	4.2	1.2	-0.0	-0.1	-0.5	2.1	0.7	0.8	1.6	0.4
Body Mass Index (BMI) (2010)	0.4	0.6	1.4	0.7	0.7	-0.9	-0.2	0.1	1.2	1.0	0.1	0.7
Coronary Artery Disease (CAD)	1.0	1.2	3.8	0.6	-0.6	-0.7	-0.6	0.8	1.9	1.7	1.1	0.6
Crohns Disease (2012)	0.4	0.6	0.9	0.9	-0.8	-0.8	-0.3	0.9	1.0	0.9	0.7	0.2
Mean Putamen Volume	0.3	0.3	1.3	0.1	0.2	0.7	0.5	0.5	-1.1	-0.7	0.3	-0.2
Fasting Glucose	1.1	1.3	2.7	0.8	0.6	-1.5	-1.5	0.6	1.6	1.6	0.7	0.4
HbA1C	0.4	0.4	2.2	-0.3	1.5	-0.4	-0.0	-0.4	0.7	0.3	-0.6	0.0
HDL Cholesterol	0.2	0.3	1.4	0.1	0.9	-0.2	-1.2	0.0	0.5	0.5	0.0	0.4
LDL Cholesterol	0.7	1.2	5.7	0.7	-2.4	0.3	1.8	0.6	0.1	0.2	0.7	0.5
Lupus	0.2	0.3	0.8	-0.1	0.9	-0.1	-0.7	-0.5	0.1	0.4	-0.3	-0.9
Neuroticism (2016)	0.7	1.1	4.1	-2.0	-0.5	-0.2	-0.0	-1.6	-0.3	-0.5	-1.2	-0.9
Primary Biliary Cirrhosis	0.1	0.2	0.6	0.0	-0.5	0.2	-0.7	-0.0	0.8	0.3	-0.2	0.2
Rheumatoid Arthritis	0.1	0.2	0.9	-0.3	-0.2	0.2	-1.0	-0.3	0.2	-0.3	-0.4	-0.3
Schizophrenia (2014)	0.1	0.2	1.3	0.5	-0.1	0.2	0.4	0.3	0.1	-0.2	0.2	-1.1
Triglycerides	1.1	1.7	6.9	0.8	-0.9	1.4	2.6	0.5	-1.6	-1.4	0.7	0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.8	0.5	-0.2	-0.5	0.2	0.4	0.1	0.9	-0.1	0.4
Ulcerative Colitis	0.8	1.1	2.8	-1.7	-0.7	-0.2	-1.5	-0.9	-0.4	-0.5	-0.6	-1.6
Blood Eosinophil Count	0.1	0.9	5.4	0.5	2.3	-0.1	-1.3	0.0	-0.4	-0.3	0.5	-0.0
Blood Platelet Count	0.3	3.5	15.8	-2.3	-0.8	0.2	4.0	-1.6	-0.6	-0.7	-1.8	-1.7
Blood Red Count	0.1	1.2	6.0	2.4	-0.0	0.8	0.8	1.3	-0.3	-0.3	1.1	0.1
Blood White Count	0.1	0.5	1.7	-1.0	1.3	-0.4	1.0	0.0	0.0	0.3	-0.3	0.4
Heel T-Score	0.2	1.8	5.5	-1.4	0.3	0.0	1.3	-2.1	-0.3	-1.4	-2.3	-0.8
BMI	0.4	2.0	4.9	1.3	1.9	-0.8	-1.1	0.9	1.6	2.2	0.7	1.6
Height	0.2	3.8	28.2	-1.0	1.3	-1.1	-5.3	-0.9	-0.2	0.0	-0.9	0.7
Waist Hip Ratio (WHR)	0.1	0.5	2.5	-0.0	-1.6	-0.5	0.4	0.8	0.6	0.6	0.3	0.1
Systolic Blood Pressure	0.2	0.8	2.8	-0.3	-0.2	-0.4	-1.7	-1.3	0.2	0.1	-1.4	-0.5
Smoking Status	0.5	1.1	3.0	-0.4	-1.5	1.4	1.7	-0.5	-0.7	-1.1	-0.5	0.2
Allergy or Eczema	0.2	0.5	1.7	0.6	1.3	0.0	-1.2	0.0	0.8	-0.1	0.2	-0.3
Cardiovascular Disease	0.4	1.2	2.8	-0.7	0.1	-0.9	-1.1	-1.3	1.7	1.4	-1.4	-0.3
Hypothyroidism (self reported)	2.1	4.8	8.8	2.2	1.7	-2.2	-2.9	1.5	2.5	3.0	1.3	1.9
Respiratory disease	0.1	0.3	1.2	0.3	1.1	-0.3	-0.7	-0.0	0.4	0.1	0.2	-0.5
Type 2 Diabetes (T2D) (2018)	1.3	2.4	5.9	2.4	2.0	0.2	1.0	1.9	0.2	1.0	1.6	1.9
Lung FEV1/FVC ratio	0.1	0.4	0.9	-0.2	1.0	0.4	-0.4	0.1	-1.0	-0.8	-0.2	0.7
Lung FVC	0.3	1.3	5.4	1.3	1.2	0.2	2.3	0.5	0.1	-0.4	1.1	-1.1
Neuroticism	0.1	0.3	0.4	-0.6	0.4	0.6	0.6	-0.5	-0.2	-0.6	-0.1	-0.6
Chronotype (morning person)	0.6	1.3	3.8	-0.8	-1.9	-1.6	-1.1	0.1	1.4	1.2	0.2	0.4
Hair Pigment	0.1	3.3	10.5	-0.2	0.6	-2.0	-3.2	0.5	2.5	2.5	1.0	0.5
Tanning	0.2	2.1	7.2	0.7	0.4	1.1	2.7	1.0	-2.1	-2.0	0.7	0.3
Hand grip strength (left)	0.3	0.7	2.1	1.3	-1.4	-0.2	-0.5	0.6	0.7	0.5	0.6	0.6
Number of treatments/medications taken	0.8	1.4	3.2	-1.7	1.8	0.6	-0.1	-1.2	-0.6	-1.0	-1.5	-1.2
Average weekly spirits intake	0.4	0.5	1.7	-0.9	0.6	-0.9	-1.3	-0.6	0.3	0.4	-0.6	-0.6
Sensitivity / hurt feelings	0.2	0.3	1.6	-0.4	1.2	0.4	-0.6	0.4	0.4	-0.2	0.5	-0.3
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.2	-1.1	1.1	-0.3	0.3	-0.5	-0.5	-0.5	-0.5	-0.7
Hearing difficulty/problems: Yes	1.0	1.6	3.1	0.1	1.5	1.4	1.7	0.2	-1.8	-1.7	0.3	1.1
Relative age of first facial hair	0.3	0.6	1.6	-0.1	1.1	-0.0	-0.5	-1.0	-0.7	-0.7	-0.7	-1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	3.0	-0.5	1.7	-0.4	-1.3	-0.1	0.5	0.3	-0.1	-0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	0.1	0.6	0.1	-0.3	-0.3	-0.2	0.2	-0.6	-0.1
Ever had hysterectomy (womb removed)	0.3	0.4	1.3	-0.6	0.0	-0.5	-1.1	-0.6	0.4	0.8	-0.5	-0.3
Systolic blood pressure, automated reading	0.3	1.0	5.1	-0.0	1.0	-0.8	-2.2	-0.3	0.5	0.9	-0.5	0.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	4.0	1.2	2.0	0.3	0.3	0.6	-0.7	-0.1	0.5	0.4
Angina	0.1	0.2	1.3	-0.5	0.2	0.1	0.2	-0.1	-0.1	0.1	-0.1	-1.1
Medication for hormone replacement therapy	0.3	0.3	1.5	0.9	1.2	-0.5	-0.2	0.5	-0.2	0.3	-0.1	-0.2
Vitamin and mineral supplements	0.4	0.5	2.1	1.2	-1.5	0.5	0.7	0.3	-0.1	0.2	0.3	0.3
Supplements: Zinc	0.9	1.0	3.2	0.8	1.8	-0.7	-0.1	1.3	0.7	0.9	0.9	0.9
Medication: Co-codamol	2.1	2.4	5.7	-2.1	1.8	-0.5	-0.6	-2.3	-0.1	-0.4	-2.4	-1.6
Medication: Metformin	1.1	1.6	4.0	1.7	0.3	0.7	1.3	2.0	-0.2	0.7	1.6	1.3
Diabetes (father)	0.1	0.1	0.3	0.0	-0.3	-0.0	0.5	0.4	-0.0	-0.1	0.4	0.1
Diabetes (mother)	0.3	0.3	1.3	-0.6	-0.4	0.3	0.1	-0.4	-1.2	-1.0	0.1	-0.0
Severe depression (siblings)	0.6	0.7	1.7	-1.1	0.8	-1.3	-0.3	0.0	1.1	0.9	-0.2	-0.5
Pack years adult smoking proportion	0.2	0.3	0.9	-0.5	0.5	0.2	0.6	-0.6	-0.3	-0.0	-0.2	-1.0
Impedance of leg (right)	0.0	0.1	0.5	0.4	0.5	0.1	-0.7	0.0	-0.0	-0.5	0.0	-0.0
Leg fat-free mass (left)	0.2	0.8	3.2	-0.2	1.5	-0.2	-1.8	0.2	0.2	0.6	-0.0	1.2
Trunk fat percentage	0.6	2.3	10.8	0.9	3.3	1.2	-0.7	1.1	-0.6	-0.4	0.8	2.2
Hand grip strength (right)	0.4	1.1	3.5	1.1	-0.7	-0.9	-1.9	0.4	1.1	1.0	0.6	1.0
Townsend deprivation index at recruitment	0.3	0.4	1.7	-0.5	-1.3	0.2	0.5	0.4	-0.6	-0.5	0.3	-0.3
Current tobacco smoking	1.1	1.8	5.5	-0.3	-2.4	1.2	1.9	-0.4	-1.6	-1.5	-0.4	-0.2
Average weekly fortified wine intake	1.4	1.6	4.2	-0.7	2.0	-1.1	-2.0	-1.4	-0.5	-0.2	-1.3	-0.7
Maternal smoking around birth	0.9	1.4	3.2	-1.2	-0.2	-1.7	0.1	-1.8	0.2	0.9	-1.6	-1.1
Fed-up feelings	0.2	0.3	0.9	-1.0	0.4	0.1	0.7	-0.5	-0.3	-0.3	-0.4	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.6	-0.6	0.8	1.2	1.6	-1.0	-2.1	-1.9	-1.0	-0.4
Relative age voice broke	0.8	1.2	5.3	-1.0	0.4	0.0	0.7	-1.1	-0.7	-1.1	-0.9	-2.3
Taking other prescription medications	1.1	1.7	5.1	-1.1	2.3	1.3	0.0	-0.7	-1.5	-1.7	-1.0	-0.7
Age when periods started (menarche)	1.2	3.0	5.9	-2.4	-0.8	0.2	0.1	-2.3	-1.3	-1.5	-2.4	-2.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.3	0.2	0.4	-0.4	-0.9	0.1	0.4	1.1	-0.4	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.0	-1.0	0.6	-0.6	0.7	-0.5	0.8	0.1	-0.5	-0.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.8	-1.7	0.5	-0.2	-0.6	-0.8	-0.0	0.0	-1.0	-1.4
Qualifications: CSEs or equivalent	0.1	0.1	0.3	-0.0	0.0	0.2	0.2	-0.4	0.2	-0.2	-0.5	0.4
Serious illness, injury or assault to yourself	1.0	1.2	2.7	0.8	1.6	0.9	0.4	1.5	-1.0	-0.8	1.3	1.1
High blood pressure	0.2	0.6	2.4	-0.5	0.4	0.2	-0.6	-1.3	0.2	0.3	-1.6	-0.5
Hayfever, allergic rhinitis or eczema	0.4	0.9	3.6	1.0	1.9	-0.2	-1.3	0.3	1.2	0.2	0.2	-0.2
Multivitamins +/- minerals	1.1	1.4	4.6	-1.4	2.2	-1.5	-0.8	-0.9	0.6	0.4	-0.7	-1.1
Stomach or abdominal pain in last month	1.2	1.5	4.0	0.2	1.9	1.1	1.6	0.3	-2.0	-1.5	0.2	-0.0
Supplements: Glucosamine	1.7	2.2	5.2	-1.0	2.2	2.2	0.2	-0.9	-1.6	-2.3	-0.8	-0.4
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.8	0.6	2.1	-0.3	-1.9	1.2	1.1	1.2	1.4	2.2
Medication: Atenolol	1.9	2.4	6.5	-2.5	1.1	-0.8	-1.4	-1.9	1.0	0.7	-1.3	-2.1
Medication: Levothyroxine sodium	2.2	3.7	8.9	0.9	2.1	-2.5	-2.4	0.6	2.4	3.0	0.4	0.8
Sitting height	0.2	1.1	5.5	-1.1	0.5	0.3	-2.4	-1.0	-0.6	-0.8	-0.9	0.4
Chronic bronchitis/emphysema (father)	4.7	5.5	9.1	2.0	-0.1	2.7	2.5	2.3	-2.9	-2.3	2.0	3.0
High blood pressure (mother)	0.4	0.6	2.9	-0.2	-1.7	-0.1	0.2	-0.6	0.2	0.4	-0.7	-1.2
Body mass index (BMI)	0.3	1.4	4.4	1.2	2.1	0.2	-0.2	1.1	0.4	1.0	0.9	1.8
Impedance of leg (left)	0.0	0.1	0.3	0.5	-0.4	-0.1	-0.5	0.0	-0.0	-0.4	0.1	-0.3
Leg predicted mass (left)	0.2	0.9	3.3	-0.1	1.5	-0.2	-1.8	0.2	0.2	0.7	0.0	1.3
Trunk fat mass	0.5	2.3	10.3	0.8	3.2	0.8	-1.4	1.0	-0.3	0.1	0.7	2.3
Waist circumference	0.4	1.6	2.7	1.1	1.6	-0.4	-1.5	1.3	1.1	1.6	0.9	1.6
Number of incorrect matches in round	0.4	0.6	1.8	-1.0	0.4	-0.7	-1.4	-1.0	0.5	0.5	-0.9	-0.0
Past tobacco smoking	0.1	0.2	0.9	0.5	0.1	-0.9	-0.6	-0.1	0.4	0.4	0.3	-0.4
Alcohol usually taken with meals	0.6	1.0	2.7	1.0	0.2	-0.9	-1.3	0.2	1.5	1.6	0.3	0.6
Nervous feelings	0.3	0.6	2.5	-1.6	-0.3	0.5	0.4	-0.3	-0.7	-1.1	-0.2	-0.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	1.9	4.6	-1.1	0.8	1.1	2.1	-0.8	-1.9	-2.0	-0.8	-1.0
Hearing difficulty/problems with background noise	1.1	1.7	7.4	0.7	2.7	1.1	1.1	0.9	-1.0	-1.2	1.0	1.0
Hair/balding pattern: Pattern 2	0.3	0.3	1.0	-0.8	-0.5	-0.3	0.1	-0.8	0.2	0.1	-0.5	-1.0
Had menopause	0.1	0.2	0.8	-0.6	0.2	-0.2	-0.9	-0.2	-0.4	-0.1	-0.1	-0.2
Had other major operations	1.4	1.7	3.6	0.9	1.1	-0.3	-1.9	1.5	1.1	0.8	1.4	1.8
Forced vital capacity (FVC)	0.2	0.6	1.4	0.3	1.1	-0.9	-1.2	-0.3	1.1	0.6	-0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	2.7	-1.6	0.3	-0.2	1.5	-1.5	0.2	-0.7	-1.7	-1.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.7	1.3	0.9	0.9	-0.1	1.0	0.3	0.2	0.7	0.6
Qualifications: None of the above	0.3	0.7	2.6	-0.6	1.3	0.1	0.6	-0.4	-0.0	0.1	-1.1	-1.6
Financial difficulties in last 2 years	0.2	0.3	2.0	0.1	1.4	0.1	0.4	-0.2	-0.3	-0.2	-0.1	0.7
Mouth/teeth dental problems	0.6	1.0	3.5	0.9	1.9	-0.2	-1.0	-0.5	0.5	0.3	-0.3	-1.7
Heart attack	1.2	1.5	6.0	-1.7	2.4	-0.5	-0.3	-1.1	1.0	0.6	-0.9	-1.1
Allergy	0.1	0.3	0.7	-0.5	-0.4	-0.0	0.9	-0.4	-0.8	-0.0	-0.4	0.6
Pain all over the body in last month	0.1	0.2	0.4	0.3	-0.3	0.1	0.6	0.4	-0.4	0.2	0.5	-0.4
Diabetes (self-reported)	3.8	5.9	9.9	2.8	1.5	2.1	2.9	3.1	-1.8	-0.6	2.9	2.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.3	-0.4	0.9	-0.8	-1.2	-0.5	0.2	-0.3	-0.2	-0.9
Medication: Ramipril	0.3	0.4	1.5	0.2	-0.1	0.5	1.2	-0.7	-0.3	-0.3	-0.9	0.6
Medication: Simvastatin	0.2	0.3	0.7	0.4	-0.2	-0.1	-0.1	0.8	0.8	0.8	0.8	0.2
Fluid intelligence score	0.4	0.8	2.7	0.3	-0.4	-1.3	-0.7	0.1	1.7	1.5	0.2	-0.2
Illnesses of siblings	0.9	1.3	3.9	-0.4	1.4	-1.8	-2.0	-0.6	0.7	1.2	-0.7	0.2
Neuroticism score	0.3	0.7	1.8	-1.4	1.2	0.4	0.4	-0.7	-0.3	-1.0	-0.4	-1.1
Weight	0.4	1.8	5.2	0.6	2.3	-0.2	-2.2	0.8	0.4	1.0	0.5	2.0
Impedance of arm (right)	0.2	0.9	3.0	-0.1	0.7	1.4	-0.5	-0.2	-1.3	-1.7	-0.3	0.1
Arm fat percentage (right)	0.5	2.0	7.8	1.4	2.8	1.0	-0.4	1.2	-0.2	0.2	0.9	2.1
Trunk fat-free mass	0.2	1.3	7.1	-0.3	0.5	-1.2	-2.7	0.0	0.9	1.4	0.0	0.6
Hip circumference	0.7	2.8	9.8	0.4	2.7	-1.1	-3.1	0.3	1.4	1.9	0.2	1.2
Time employed in main current job	1.4	1.6	7.0	-0.5	-2.6	0.9	1.5	-0.1	-1.4	-1.4	0.3	-0.3
Alcohol intake versus 10 years previously	1.0	1.5	3.4	1.6	-0.0	1.8	1.4	1.1	0.7	0.1	0.9	1.8
Father’s age at death	1.2	1.6	3.5	-1.8	1.9	-0.2	-0.3	-1.3	-1.4	-1.4	-1.2	-0.8
Worrier / anxious feelings	0.6	1.2	3.6	-1.9	-0.2	-1.1	0.5	-1.1	0.1	-0.1	-1.1	-1.7
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	6.4	1.1	1.0	1.9	2.5	1.0	-1.1	-1.2	1.1	1.0
Falls in the last year	0.9	1.2	2.5	1.6	1.4	0.7	0.1	1.2	0.7	0.4	1.1	1.4
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	-0.8	0.9	-0.5	-0.1	-0.8	0.7	0.5	-1.2	-0.5
Number of live births	0.4	0.6	1.8	-0.6	-0.9	0.1	0.6	0.1	-1.4	-1.3	0.1	0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.7	0.8	1.6	-0.7	-1.0	0.1	1.1	0.5	0.3	0.4
Pulse rate	0.6	1.0	2.8	1.1	-1.0	-0.5	0.2	0.2	1.5	1.7	-0.0	1.2
Happiness	0.1	0.1	0.6	-0.8	0.1	-0.2	-0.4	-0.4	0.3	0.1	-0.2	-0.2
Noisy workplace	0.1	0.1	0.5	-0.0	-0.7	0.1	0.6	0.1	-0.4	0.0	0.3	0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.6	0.6	0.7	0.4	-1.0	0.9	0.5	0.5	1.2	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.4	0.4	-0.9	-0.1	0.5	0.9	0.0	0.2	1.2	0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	0.9	-0.1	-0.7	0.4	0.3	1.0	-0.1	0.1	0.8	0.8
Asthma	0.3	0.5	2.5	0.7	1.6	0.4	-0.3	0.6	0.1	-0.3	1.1	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	-0.6	0.7	0.4	1.0	-0.1	-0.1	-0.3	-0.3	-0.3
Medication: Cholesterol lowering	0.9	1.5	4.2	0.1	-1.2	2.0	1.6	0.6	-1.4	-1.6	0.3	0.4
Depression (self-reported)	0.7	0.9	2.0	0.6	0.6	-0.0	-0.2	1.2	1.3	1.2	0.8	1.4
Medication: Lansoprazole	0.8	0.9	2.2	-1.1	1.5	-0.8	-0.6	-0.7	0.9	0.7	-0.6	-1.0
Prospective memory result	1.2	1.4	3.0	-1.2	-0.3	0.6	0.4	-1.1	-1.7	-1.4	-1.2	-1.7
Lung cancer (father)	1.0	1.2	2.8	1.4	-0.5	1.3	1.2	1.3	-0.5	-0.4	0.7	1.7
Illnesses of mother	0.2	0.2	0.9	0.9	0.1	0.1	0.5	0.5	-0.0	0.1	-0.1	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.3	1.1	0.9	0.1	-0.4	0.5	0.0	-0.3	0.6	0.3
Pulse wave Arterial Stiffness index	0.2	0.3	1.0	-0.4	-1.0	-0.5	-0.4	0.2	0.1	0.5	0.5	0.5
Impedance of arm (left)	0.1	0.4	1.6	-0.1	0.3	0.9	-0.5	-0.1	-0.7	-1.3	-0.2	0.1
Arm fat mass (right)	0.4	1.6	6.6	1.0	2.6	0.7	-0.9	0.9	-0.3	0.3	0.7	1.9
Trunk predicted mass	0.2	1.3	6.8	-0.3	0.4	-1.2	-2.6	0.1	0.9	1.4	0.1	0.6
Standing height	0.3	2.6	19.9	-1.2	0.6	-0.7	-4.5	-0.6	0.1	0.1	-0.7	0.5
Length of working week for main job	0.7	0.8	3.2	-0.9	-1.8	-0.3	-0.7	-0.6	-0.5	-0.7	-1.0	-0.4
Exposure to tobacco smoke at home	0.5	0.5	1.1	0.0	-0.1	-0.9	-1.1	-0.2	1.0	1.0	-0.8	-0.3
Breastfed as a baby	1.3	1.6	6.1	-1.1	2.5	-1.2	-1.8	-1.2	0.5	0.3	-1.1	-0.0
Tense / ‘highly strung’	0.3	0.6	2.3	-0.2	-0.1	1.5	0.8	-0.3	-0.5	-1.2	-0.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.9	0.3	0.5	0.9	0.9	0.1	-0.8	-0.6	0.5	0.1
Hair/balding pattern: Pattern 4	0.7	1.8	4.6	0.5	-0.8	1.5	2.1	0.8	-1.9	-1.8	1.0	0.4
Birth weight of first child	0.1	0.2	1.0	-0.9	-1.0	0.1	0.4	0.2	-0.1	0.0	0.3	-0.1
Peak expiratory flow (PEF)	1.3	3.0	6.3	1.6	1.8	-1.2	-2.3	1.3	2.5	2.1	1.3	1.0
Pulse wave reflection index	0.7	0.8	2.4	-1.3	-0.0	0.5	0.6	-0.6	-1.5	-1.5	-0.5	0.2
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.7	0.3	1.2	1.6	1.2	0.4	-0.9	-1.6	0.3	0.6
Loud music exposure frequency	0.7	0.8	2.5	1.6	1.3	0.6	0.6	0.4	0.4	0.3	0.2	1.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.3	0.5	-0.8	0.5	-0.5	0.5	-0.0	-0.1	1.1	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.8	0.6	-1.1	0.6	1.4	1.7	-1.1	-0.4	1.4	1.5
Blood clot in the leg (DVT)	0.3	0.3	1.3	0.2	-0.3	1.1	-0.1	0.8	0.0	-0.4	0.7	0.4
Medication: Paracetamol	1.2	2.0	3.5	-1.5	1.1	-1.7	-1.0	-1.5	1.3	1.1	-1.5	-1.9
Headache pain in last month	1.5	2.6	5.3	-1.8	1.7	0.1	1.8	-1.4	-1.7	-1.7	-1.1	-2.3
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.3	-0.2	1.2	-2.1	-1.1	-0.2	1.1	1.3	-0.0	-0.2
Glaucoma (self-reported)	1.3	1.5	4.7	1.4	-0.7	2.2	1.6	1.1	-0.9	-0.7	1.1	0.6
Gout (self-reported)	1.5	2.1	4.8	-1.4	-1.5	0.7	1.1	-2.0	-1.0	-1.2	-2.2	-1.2
Hypothyroidism/myxoedema (self-reported)	1.8	3.4	6.4	1.7	2.2	-1.4	-2.5	1.6	1.7	2.1	1.5	1.8
Medication: Amlodipine	0.3	0.4	2.6	-0.3	1.6	-0.1	-0.6	-0.3	0.6	0.4	-0.3	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.2	-0.2	0.8	-0.3	0.1	0.3	-0.3	0.3	-0.6
Birth weight	0.6	1.3	5.3	-1.1	-2.3	0.0	0.5	0.8	-0.8	-0.5	0.8	1.7
Chronic bronchitis/emphysema (mother)	0.9	1.1	3.4	-0.1	1.8	-1.3	-1.4	-0.8	0.9	0.8	-0.4	-0.5
High blood pressure (siblings)	1.2	1.8	5.9	-0.3	-2.4	1.7	1.6	-0.8	-1.2	-1.2	-0.5	-1.0
Forced vital capacity (FVC), Best measure	0.1	0.3	1.0	0.6	0.8	-0.5	-1.0	0.0	0.4	0.1	0.2	-0.0
Body fat percentage	0.5	1.8	9.1	0.9	3.0	1.0	-0.6	0.8	-0.3	-0.1	0.5	2.0
Leg fat percentage (right)	0.5	1.7	5.7	1.3	2.4	0.8	-0.2	1.3	0.1	0.3	1.0	2.1
Arm fat-free mass (right)	0.2	1.2	4.7	-0.1	0.7	-1.3	-2.2	0.1	1.1	1.6	-0.0	0.7
Exposure to tobacco smoke outside home	0.3	0.4	1.2	1.0	1.1	0.5	0.7	0.2	-0.6	-0.4	0.1	0.2
Comparative body size at age 10	0.1	0.2	1.6	0.3	-0.3	-0.0	0.4	0.0	-0.1	0.4	-0.2	1.3
Number of full brothers	2.7	3.4	9.0	-1.6	0.6	-3.0	-1.5	0.1	2.7	2.2	0.1	-2.0
Worry too long after embarrassment	0.5	0.9	4.2	-1.2	2.1	0.0	-0.3	-0.3	-0.3	-1.1	-0.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	2.6	1.1	1.1	1.1	1.5	1.4	-0.7	-0.6	1.1	1.6
Wheeze or whistling in the chest in last year	1.3	2.3	13.7	0.8	3.7	1.3	0.6	0.8	-0.3	-0.7	1.1	1.3
Number of children fathered	0.9	1.1	2.7	-1.5	-0.2	-0.7	-0.9	-1.6	0.1	-0.2	-1.6	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	2.5	-1.2	1.2	-1.4	-1.6	-1.6	1.3	1.0	-1.3	-0.4
Age at first live birth	0.3	0.5	2.5	0.4	0.7	0.8	1.6	0.1	-0.1	-0.7	0.4	0.4
Pulse wave peak to peak time	0.2	0.2	1.0	0.4	1.0	0.2	-0.0	-0.2	0.0	-0.3	-0.5	-0.4
Health satisfaction	0.5	0.6	1.7	-1.3	0.8	1.0	-0.0	-0.0	-0.4	-1.3	0.1	-0.1
Shortness of breath walking on level ground	0.3	0.3	1.0	-0.3	0.7	0.8	1.0	-0.4	-0.4	-0.5	-0.0	-0.5
Qualifications: College or University degree	0.1	0.2	0.5	0.0	0.7	0.3	-0.6	-0.5	0.0	-0.3	-0.2	-0.3
Eye problems/disorders: None of the above	1.2	1.4	3.2	-1.2	-1.0	-1.6	0.1	-1.6	0.4	0.4	-1.8	-1.1
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.0	-0.8	-0.2	-0.8	-0.6	-0.8	-0.0	0.4	-1.0	0.0
Emphysema/chronic bronchitis	0.3	0.3	1.8	-0.4	-1.3	-0.4	0.5	-0.2	0.3	0.2	-0.4	-0.6
Medication for pain relief, constipation, heartburn	1.0	1.7	4.1	1.8	-0.5	1.1	0.5	1.4	-1.0	-1.0	1.6	2.0
Neck or shoulder pain in last month	1.0	1.5	3.2	-1.4	0.8	-0.1	1.8	-1.5	-0.5	-0.8	-1.5	-1.4
Medication: Blood pressure	0.2	0.3	2.0	0.1	0.2	1.4	-0.0	-0.1	0.1	-0.3	-0.4	0.4
Angina (self-reported)	0.1	0.2	1.3	-0.4	0.2	-0.1	0.0	-0.0	0.3	0.5	-0.1	-1.1
Migraine (self-reported)	1.1	1.3	4.5	-1.4	-0.3	-1.0	1.1	-1.2	0.1	-0.1	-1.3	-2.1
Medication: Ibuprofen	0.7	0.8	2.4	-0.7	1.5	0.7	1.3	-0.6	-0.5	-0.8	-0.9	-0.1
Medication: Allopurinol	0.4	0.5	1.8	-0.6	-0.8	0.1	0.5	-1.2	-0.5	-0.3	-1.3	-0.4
Medication: Omeprazole	0.8	0.9	4.8	-0.7	-2.2	0.2	0.9	-0.6	-1.0	-0.4	-0.8	-0.1
Medication: Seretide 50 evohaler	1.1	1.3	4.5	-1.1	-1.0	-0.6	0.3	-1.5	-0.3	-0.3	-1.3	-2.1
Mean time to correctly identify matches	1.5	2.8	7.9	-0.2	-0.9	-1.7	-2.8	0.4	2.3	2.8	0.6	-0.7
Heart disease (mother)	0.8	1.0	1.8	1.2	-1.0	-0.3	-0.4	1.0	0.8	1.3	1.1	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	-1.1	-0.3	0.2	1.0	-0.5	-0.0	-1.0	-0.3	-1.2
Whole body fat mass	0.4	1.8	8.6	0.8	2.9	0.6	-1.2	0.8	-0.3	0.1	0.6	2.0
Leg fat mass (right)	0.6	2.1	8.2	1.4	2.9	0.8	-0.7	1.3	-0.1	0.3	1.0	2.3
Arm predicted mass (right)	0.2	1.1	4.6	-0.4	0.6	-1.3	-2.1	-0.3	0.9	1.4	-0.3	0.4
Pulse rate, automated reading	1.0	3.1	11.6	0.1	-2.8	2.0	3.4	-0.2	-1.6	-1.4	-0.2	0.0
Alcohol intake frequency.	1.9	4.4	8.0	1.5	1.1	2.8	2.7	2.5	-2.0	-1.4	1.9	2.2
Comparative height size at age 10	0.1	0.7	4.9	-0.0	0.5	0.1	-2.2	0.7	-0.6	-0.4	0.4	0.6
Number of full sisters	0.1	0.2	0.5	-0.2	0.7	0.5	0.3	-0.2	0.0	-0.5	-0.5	-0.4
Suffer from ‘nerves’	0.9	1.4	4.2	-0.6	-1.0	1.5	2.1	-0.3	-1.1	-1.7	-0.1	-0.9
Overall health rating	0.3	0.6	2.7	-0.4	1.6	-0.7	0.5	0.2	1.0	0.9	-0.2	-0.1
Chest pain or discomfort	1.5	2.2	4.0	1.4	1.9	1.9	1.6	1.1	-0.8	-1.0	1.1	2.0
Had major operations	0.7	0.8	4.1	-0.3	2.0	-0.5	-0.7	-0.7	-0.4	-0.5	-0.7	-0.9
Age at last live birth	0.9	1.3	4.1	-0.8	0.8	0.6	2.0	-0.6	-1.4	-1.9	-0.1	-0.5
Family relationship satisfaction	0.4	0.5	1.6	-0.1	-0.3	-0.5	-1.2	0.2	1.0	0.8	0.4	0.9
Leg pain on walking	0.4	0.4	1.3	-0.1	-1.1	0.4	1.1	0.1	-0.0	-0.1	0.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.6	1.3	-1.0	0.4	0.9	1.3	-0.3	0.2	1.4	1.6
Commuting to job workplace: Car/motor vehicle	1.6	1.8	5.2	-1.7	0.4	-0.6	0.4	-2.3	-0.6	-0.5	-2.1	-1.7
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.3	-0.5	-0.8	-0.4	-0.9	-1.3	0.5	0.2	-1.5	-0.2
Medication: Aspirin	1.3	1.7	7.9	-1.7	-0.5	-0.0	0.3	-1.3	-0.1	-0.3	-1.4	-2.8
Supplements: Vitamin C	0.3	0.4	1.0	-0.7	-1.0	0.3	1.0	0.3	0.4	0.0	0.4	-0.7
Knee pain experienced in last month	0.7	1.1	4.4	-0.1	0.3	2.1	1.2	-0.0	-1.0	-1.5	-0.1	0.6
Hypertension (Self-reported)	0.3	0.8	2.8	-0.5	0.1	-0.0	-0.9	-1.4	0.7	0.9	-1.7	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.9	-1.3	0.5	-0.6	-0.3	-1.4	0.2	0.2	-1.7	-0.7
Illnesses of father: Heart disease	2.5	3.5	10.4	-0.8	-0.5	-3.2	-1.9	-1.6	2.0	2.5	-1.7	-1.1
Illnesses of siblings: Diabetes	2.1	2.5	4.4	1.6	-0.5	1.7	2.1	2.1	-0.5	-0.9	2.1	1.7
Smoking status: Previous	0.1	0.1	0.5	-0.4	0.3	0.5	0.1	0.2	0.2	0.1	0.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	2.4	-1.0	0.3	-0.1	-1.5	-1.4	-0.0	-0.2	-1.0	-0.2
Whole body fat-free mass	0.2	1.1	5.5	-0.2	0.8	-1.0	-2.3	0.1	0.7	1.3	0.0	0.8
Leg fat-free mass (right)	0.1	0.6	2.7	-0.2	0.9	-0.5	-1.6	0.1	0.2	0.7	-0.1	0.9
Arm fat percentage (left)	0.5	2.2	7.0	1.5	2.6	1.2	-0.2	1.4	-0.3	0.1	1.1	2.4
Average weekly red wine intake	0.4	0.6	1.2	-0.8	1.1	-0.2	-0.9	-0.9	-0.5	-0.6	-0.6	-0.8
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.6	0.2	1.2	1.3	-0.1	-0.4	-1.4	-1.6	-0.7	1.4
Mood swings	0.1	0.1	0.4	0.4	-0.5	0.6	0.2	0.3	0.4	0.2	0.3	-0.2
Loneliness, isolation	1.8	2.5	8.8	-1.5	-0.7	-1.6	-0.3	-1.4	1.6	1.4	-1.4	-3.0
Long-standing illness, disability or infirmity	1.1	1.7	6.1	1.2	2.5	0.0	-0.2	1.5	0.6	0.6	1.5	1.6
Ever had bowel cancer screening	0.7	0.8	2.0	-0.9	0.3	-1.0	-1.4	0.1	1.4	0.9	-0.0	-0.8
Diabetes diagnosed by doctor	2.0	3.4	7.7	2.4	1.9	0.6	1.5	2.8	-0.3	0.7	2.5	2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.7	-0.0	0.6	-0.7	0.8	-0.1	0.2	-0.0	0.1	0.2
Friendships satisfaction	0.9	1.1	7.3	-1.1	-2.7	-0.6	0.2	-0.6	0.2	0.3	-0.9	-0.3
Qualifications: nursing, teaching	1.2	1.8	3.2	1.6	0.6	1.6	0.2	1.7	-0.7	-1.1	1.8	1.7
Commuting to job workplace: Walk	0.2	0.3	0.8	0.5	-0.3	0.9	0.5	0.4	-0.0	-0.4	0.4	-0.7
Eye problems/disorders: Cataract	0.8	0.9	2.7	0.8	0.0	1.3	-0.6	1.5	0.0	-0.1	1.6	0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.5	-1.2	0.3	-0.5	-0.2	-0.4	0.5	0.0	-0.0	0.8
Medication for cholesterol	0.1	0.2	1.5	-0.0	-1.2	0.0	0.2	-0.4	0.0	-0.5	0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.7	-0.5	1.0	-0.5	-1.3	-0.2	0.5	0.3	-0.1	-0.1
Back pain experienced in last month	0.4	0.6	1.3	-0.6	-0.6	1.0	1.0	0.0	-0.9	-1.1	-0.1	-0.5
Mineral and other dietary supplements	0.8	1.1	3.7	1.0	-1.9	-0.8	0.6	0.9	0.5	1.3	1.0	0.7
Breast cancer (self-reported)	0.6	0.7	1.4	-0.6	0.7	-1.2	-0.7	0.8	1.2	0.9	0.4	-0.6
Asthma (self-reported)	0.2	0.3	1.5	0.3	1.2	0.4	-0.3	0.4	0.1	-0.3	0.9	-0.3
Osteoporosis (self-reported)	1.0	1.2	3.4	-0.9	1.8	0.9	-0.9	-1.0	-0.7	-1.4	-0.7	-0.9
Osteoarthritis (self-reported)	0.5	0.7	1.7	-1.3	1.0	-0.0	0.2	-0.9	0.1	-0.1	-1.3	-1.0
Medication: Aspirin	1.0	1.3	5.6	-1.4	-0.4	0.3	0.6	-1.2	-0.1	-0.4	-1.3	-2.4
Medication: Gliclazide	1.6	1.8	3.3	1.5	-1.8	0.3	1.8	1.3	1.1	1.4	1.0	1.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	-0.3	0.7	0.4	-0.3	0.2	0.1	-0.3	0.2	0.1
Smoking status: Current	1.1	1.7	4.5	-0.1	-1.9	1.3	2.1	-0.4	-1.7	-1.6	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.8	-0.4	0.9	-1.2	-0.1	-1.0	1.1	0.5	-1.0	-1.7
Whole body water mass	0.2	1.1	5.8	-0.3	0.8	-0.9	-2.4	-0.0	0.7	1.2	-0.1	0.7
Leg predicted mass (right)	0.1	0.6	2.8	-0.3	0.8	-0.5	-1.7	-0.0	0.3	0.8	-0.1	0.9
Arm fat mass (left)	0.5	2.1	6.7	1.5	2.6	0.8	-0.7	1.4	-0.3	0.3	1.2	2.4
Number of self-reported non-cancer illnesses	0.5	0.9	4.1	-1.2	2.0	0.1	-0.9	-0.4	0.6	0.3	-0.6	-0.8
Average weekly champagne plus white wine intake	0.7	0.9	2.6	0.9	-1.3	1.6	1.0	0.2	-1.2	-0.9	-0.1	0.5
Miserableness	0.2	0.4	1.5	0.1	0.5	0.7	1.2	0.0	-0.8	-0.8	-0.1	-0.4
Guilty feelings	0.2	0.3	1.4	-0.7	0.3	0.4	-1.2	-0.5	-0.5	-0.5	-0.1	-0.3
Wears glasses or contact lenses	0.1	0.1	0.5	0.2	-0.0	0.5	0.7	0.4	0.1	-0.1	0.3	-0.2
Ever taken oral contraceptive pill	1.2	1.3	3.2	-1.4	-1.8	0.5	1.8	-0.9	-0.9	-1.0	-0.6	-0.5
Hearing aid user	0.4	0.5	2.5	-0.4	-1.6	-0.8	0.2	0.2	0.2	0.4	0.2	-0.8
Mother’s age at death	0.9	1.1	3.0	0.0	0.7	-0.9	-1.4	0.2	1.7	1.7	-0.1	0.9
Financial situation satisfaction	1.4	1.7	3.6	-1.4	1.3	-1.8	-1.9	-0.8	1.3	1.3	-0.7	0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	0.4	-0.2	0.5	0.4	0.5	-0.1	-0.4	0.1	1.1
Commuting to job workplace: Public transport	1.8	2.1	4.4	1.3	-0.3	-1.0	-1.0	2.1	1.9	1.6	2.0	0.7
Eye problems/disorders: Glaucoma	0.8	1.0	2.6	1.1	-1.3	1.6	0.7	0.9	-0.7	-0.6	0.9	0.3
Medication: Blood pressure	0.3	0.6	2.4	-1.5	0.3	0.3	-0.2	-1.0	-0.6	-0.3	-1.1	-0.7
Pain type(s) experienced in last month: Hip pain	1.9	2.4	6.7	0.7	0.2	2.6	1.5	1.5	-1.8	-2.2	1.0	0.9
Supplements: Fish oil (including cod liver oil)	0.9	1.2	5.0	-1.1	2.2	-0.6	-1.0	-0.9	0.2	-0.2	-1.2	-0.9
High cholesterol (Self-reported)	0.6	1.0	3.2	0.4	-0.5	0.6	1.2	1.6	0.2	0.1	1.8	0.9
Medication: Bendroflumethiazide	0.9	1.4	3.5	-1.9	-0.1	1.4	0.6	-0.8	-1.7	-1.6	-0.9	-0.6
Medication: Paracetamol	1.6	2.4	5.1	-2.0	1.3	-1.2	-0.8	-2.1	0.6	0.2	-2.1	-2.3
Medication: Lisinopril	1.5	1.9	4.5	1.9	-0.3	1.9	0.1	2.1	0.4	0.2	1.8	1.5
Medication: Atorvastatin	1.9	2.4	7.3	0.5	-0.5	2.1	2.7	1.3	-1.6	-1.4	1.3	0.9
Illnesses of father: High blood pressure	0.8	1.0	2.7	-1.3	-0.4	-0.7	-0.5	-1.6	1.3	0.8	-1.1	-0.8
Alcohol drinker status: Never	0.3	0.3	1.2	0.3	-0.3	0.3	-0.3	1.1	-0.1	0.3	0.9	-0.4
Ever smoked	0.3	0.5	1.0	-0.9	-0.5	0.7	0.2	-0.6	-0.6	-0.6	-1.0	-0.4
Basal metabolic rate	0.2	1.1	5.3	-0.0	1.3	-0.7	-2.3	0.2	0.5	1.1	0.1	1.1
Leg fat percentage (left)	0.3	1.2	3.6	1.1	1.9	0.5	-0.2	1.1	0.1	0.4	0.8	1.9
Arm fat-free mass (left)	0.3	1.3	5.6	-0.3	0.9	-1.3	-2.4	-0.2	1.0	1.5	-0.2	0.4
Number of operations (self-reported)	1.1	1.7	4.0	1.0	2.0	-0.4	-1.8	1.4	0.7	0.6	1.2	1.6
Average weekly beer plus cider intake	0.3	0.4	0.9	0.5	-0.7	0.7	0.9	0.2	-0.5	-0.9	0.1	0.2
Irritability	0.1	0.2	0.8	-0.6	0.1	-0.1	0.2	-0.9	0.4	0.2	-0.6	-0.1
Risk taking	1.1	1.6	8.0	-0.6	-2.8	1.1	1.3	-0.6	-0.9	-1.2	-0.5	-0.0
Ever had prostate specific antigen (PSA) test	2.6	3.0	6.9	-2.2	0.2	0.3	-0.2	-1.9	-1.9	-1.9	-2.0	-2.6
Fractured/broken bones in last 5 years	1.1	1.4	3.4	1.1	1.5	1.9	0.8	0.4	-1.1	-1.0	0.3	1.6
Age started oral contraceptive pill	0.3	0.3	1.1	-1.0	0.2	-0.5	-0.2	-0.4	-0.3	-0.4	-0.3	-1.1
Diastolic blood pressure, automated reading	0.4	1.4	3.2	-1.2	0.6	-0.8	-1.8	-1.4	0.5	0.7	-1.7	-1.0
Ever depressed for a whole week	0.7	0.9	1.4	0.8	0.8	1.1	1.2	1.2	-0.7	-0.8	1.2	-0.0
Unable to work because of sickness or disability	0.7	0.9	3.4	1.2	-1.3	0.7	1.8	0.3	-0.8	-0.2	0.6	-0.1
Commuting to job workplace: Cycle	1.0	1.2	2.4	0.7	-0.1	1.5	0.1	1.4	-0.9	-0.9	1.3	1.6
Myopia	0.7	1.1	3.5	0.5	0.6	-1.2	-0.6	0.6	1.8	1.9	0.2	-0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.7	1.1	-0.9	-0.4	0.9	1.7	-0.0	0.1	1.9	1.1
Cholesterol lowering medication	0.7	1.1	2.6	0.8	0.1	-0.6	0.1	1.5	1.2	1.6	1.3	0.8
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.7	-1.0	-1.3	-0.8	0.2	-0.6	0.2	0.6	-0.7	-0.1
Pain experienced in last month	1.9	3.2	9.4	0.6	-0.1	-2.1	-3.1	0.1	2.4	2.7	0.4	1.3
Supplements: Calcium	0.8	0.9	3.0	0.5	1.7	0.6	1.0	1.1	-0.6	-0.9	0.9	-0.4
Basal cell carcinoma (self-reported)	0.8	1.0	4.0	0.8	-0.7	-0.2	-0.2	0.9	0.8	0.9	1.2	2.0
Heart attack/myocardial infarction (self-reported)	1.2	1.5	6.1	-1.7	2.5	-0.4	-0.3	-1.2	0.9	0.5	-1.0	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	0.1	-0.4	0.9	0.1	0.7	0.0	-0.2	0.6	0.2
Heart disease (siblings)	1.5	1.8	6.5	-0.4	-1.0	-1.7	-0.9	0.1	2.5	2.0	0.0	-0.8
Alcohol drinker status: Previous	1.2	1.4	4.0	0.2	-0.2	1.2	1.9	0.7	-2.0	-1.3	0.1	1.0
Pack years of smoking	0.2	0.3	0.9	-0.9	0.7	0.1	0.4	-0.7	-0.4	-0.1	-0.3	-0.9
Impedance of whole body	0.0	0.2	1.4	0.1	0.3	0.6	-0.3	0.1	-0.6	-1.2	0.0	0.1
Leg fat mass (left)	0.4	1.6	6.0	1.1	2.5	0.4	-0.9	1.0	-0.1	0.5	0.7	2.1
Arm predicted mass (left)	0.2	1.2	6.0	-0.3	0.7	-1.1	-2.5	-0.2	0.9	1.3	-0.3	0.5