Hub : Genes

CDK5RAP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0760 0.0220 2.1e-06 0.071 0.022 0.058 0.059 0.059 5.2e-09 1.0e-03 1.3e-07 9.4e-08 1.1e-07
2 GTEx Artery Aorta 0.2730 0.0760 5.1e-04 0.123 NA 0.120 NA 0.113 2.9e-07 NA 3.8e-07 NA 8.4e-07
3 GTEx Artery Tibial 0.0699 0.0307 9.8e-03 0.005 NA 0.036 NA 0.035 1.1e-01 NA 7.8e-04 NA 8.3e-04
4 GTEx Esophagus Muscularis 0.0980 0.0400 3.1e-03 0.017 NA 0.010 NA 0.036 3.1e-02 NA 7.5e-02 NA 3.0e-03
5 GTEx Stomach 0.2930 0.0880 2.9e-04 0.079 NA 0.013 NA 0.049 1.3e-04 NA 7.7e-02 NA 2.1e-03
6 GTEx Testis 0.3140 0.0840 9.4e-05 0.146 NA 0.054 NA 0.148 5.0e-07 NA 2.0e-03 NA 4.3e-07
7 YFS Blood 0.0386 0.0111 7.2e-07 0.031 0.026 0.037 0.032 0.038 1.8e-10 5.4e-09 2.6e-12 8.4e-11 2.2e-12
8 TCGA Breast Invasive Carcinoma 0.0201 0.0104 6.6e-04 0.026 0.008 0.024 NA 0.023 3.6e-06 8.4e-03 8.5e-06 NA 1.0e-05
9 TCGA Colon Adenocarcinoma 0.0790 0.0400 5.2e-03 -0.003 0.039 -0.003 NA -0.005 5.3e-01 2.6e-03 5.8e-01 NA 9.6e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.5 0.7 1.7 0.5 -1.0 -0.9 -0.2 1.3 0.6 0.9 1.2 -0.3
Bipolar Disorder or Schizophrenia 0.4 0.9 3.0 1.4 -0.3 0.1 0.3 1.7 0.4 0.4 1.5 -0.3
Depressed Affect (Nagel 2018) 0.1 0.2 0.6 0.3 0.0 0.5 0.8 0.7 0.2 0.2 0.6 0.4
Depression (Nagel 2018) 0.5 0.8 1.5 -1.2 0.8 0.3 0.9 -0.9 -0.9 -0.9 -1.0 -0.9
Intelligence (Savage-Jansen 2018) 0.1 0.4 2.1 0.6 -1.4 0.3 -0.6 0.3 0.4 0.3 0.5 0.5
Neuroticism (Nagel 2018) 0.1 0.2 0.5 -0.3 0.2 0.7 0.7 0.5 -0.2 -0.5 0.4 0.4
Schizophrenia (2018) 0.3 0.6 1.9 1.4 0.3 0.9 0.5 1.2 -0.0 -0.2 1.0 -0.1
Schizophrenia vs Biploar Disorder 0.6 0.8 1.9 0.0 0.6 1.0 0.6 -1.1 -0.7 -1.4 -0.9 -0.7
Worry (Nagel 2018) 0.3 0.7 2.3 -0.6 -0.0 1.3 1.2 0.1 -0.9 -1.5 0.1 0.4
Alzheimer’s Disease (in mother) 0.3 0.4 2.5 -1.6 0.7 -0.2 -0.1 -0.4 0.3 -0.2 0.0 -0.3
Alzheimer’s Disease (in father) 2.5 2.7 5.6 -2.4 -0.6 -1.5 -1.3 -1.9 0.8 0.5 -2.3 -2.0
Alzheimer’s Disease (including proxy) 0.9 1.3 5.9 -2.4 0.3 -0.8 -0.8 -1.1 0.7 0.1 -1.0 -1.4
Crohns Disease (2017) 0.5 1.2 3.0 0.9 -1.7 1.4 1.1 0.4 -1.3 -1.2 0.4 0.4
Irritable Bowel Disease (IBD) 0.4 0.8 4.8 0.0 -2.2 0.9 -0.3 -0.0 -0.8 -0.9 0.2 -0.6
Ulcerative Colitis (UC) 0.5 0.9 2.3 0.1 -1.5 1.2 -0.3 0.7 -1.1 -1.1 1.0 -0.4
Major Depression (MDD) 0.3 0.4 1.9 0.5 -0.5 -0.2 0.7 -0.1 0.4 0.3 -0.4 -1.4
Reaction Time 1.8 3.4 8.8 -0.3 -1.5 -2.0 -2.5 -0.3 2.5 3.0 -0.2 -1.7
Verbal and Numeric Reasoning (VNR) 0.2 0.4 0.9 0.9 -0.8 0.2 0.0 0.8 0.3 0.1 0.9 0.5
Breast Cancer 0.2 0.6 2.0 -0.7 -1.4 0.5 0.6 -0.4 -0.4 -0.6 -0.4 -1.1
Ovarian Cancer 3.0 4.0 9.2 0.7 -1.5 2.8 2.6 0.7 -3.0 -2.7 0.4 1.2
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.2 0.2 0.6 0.8 0.4 0.3 -0.3 0.5 0.6 0.2 0.6 0.3
Bipolar Disorder (2011) 1.1 1.1 4.2 1.2 -0.0 -0.1 -0.5 2.1 0.7 0.8 1.6 0.4
Body Mass Index (BMI) (2010) 0.4 0.6 1.4 0.7 0.7 -0.9 -0.2 0.1 1.2 1.0 0.1 0.7
Coronary Artery Disease (CAD) 1.0 1.2 3.8 0.6 -0.6 -0.7 -0.6 0.8 1.9 1.7 1.1 0.6
Crohns Disease (2012) 0.4 0.6 0.9 0.9 -0.8 -0.8 -0.3 0.9 1.0 0.9 0.7 0.2
Mean Putamen Volume 0.3 0.3 1.3 0.1 0.2 0.7 0.5 0.5 -1.1 -0.7 0.3 -0.2
Fasting Glucose 1.1 1.3 2.7 0.8 0.6 -1.5 -1.5 0.6 1.6 1.6 0.7 0.4
HbA1C 0.4 0.4 2.2 -0.3 1.5 -0.4 -0.0 -0.4 0.7 0.3 -0.6 0.0
HDL Cholesterol 0.2 0.3 1.4 0.1 0.9 -0.2 -1.2 0.0 0.5 0.5 0.0 0.4
LDL Cholesterol 0.7 1.2 5.7 0.7 -2.4 0.3 1.8 0.6 0.1 0.2 0.7 0.5
Lupus 0.2 0.3 0.8 -0.1 0.9 -0.1 -0.7 -0.5 0.1 0.4 -0.3 -0.9
Neuroticism (2016) 0.7 1.1 4.1 -2.0 -0.5 -0.2 -0.0 -1.6 -0.3 -0.5 -1.2 -0.9
Primary Biliary Cirrhosis 0.1 0.2 0.6 0.0 -0.5 0.2 -0.7 -0.0 0.8 0.3 -0.2 0.2
Rheumatoid Arthritis 0.1 0.2 0.9 -0.3 -0.2 0.2 -1.0 -0.3 0.2 -0.3 -0.4 -0.3
Schizophrenia (2014) 0.1 0.2 1.3 0.5 -0.1 0.2 0.4 0.3 0.1 -0.2 0.2 -1.1
Triglycerides 1.1 1.7 6.9 0.8 -0.9 1.4 2.6 0.5 -1.6 -1.4 0.7 0.5
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.8 0.5 -0.2 -0.5 0.2 0.4 0.1 0.9 -0.1 0.4
Ulcerative Colitis 0.8 1.1 2.8 -1.7 -0.7 -0.2 -1.5 -0.9 -0.4 -0.5 -0.6 -1.6
Blood Eosinophil Count 0.1 0.9 5.4 0.5 2.3 -0.1 -1.3 0.0 -0.4 -0.3 0.5 -0.0
Blood Platelet Count 0.3 3.5 15.8 -2.3 -0.8 0.2 4.0 -1.6 -0.6 -0.7 -1.8 -1.7
Blood Red Count 0.1 1.2 6.0 2.4 -0.0 0.8 0.8 1.3 -0.3 -0.3 1.1 0.1
Blood White Count 0.1 0.5 1.7 -1.0 1.3 -0.4 1.0 0.0 0.0 0.3 -0.3 0.4
Heel T-Score 0.2 1.8 5.5 -1.4 0.3 0.0 1.3 -2.1 -0.3 -1.4 -2.3 -0.8
BMI 0.4 2.0 4.9 1.3 1.9 -0.8 -1.1 0.9 1.6 2.2 0.7 1.6
Height 0.2 3.8 28.2 -1.0 1.3 -1.1 -5.3 -0.9 -0.2 0.0 -0.9 0.7
Waist Hip Ratio (WHR) 0.1 0.5 2.5 -0.0 -1.6 -0.5 0.4 0.8 0.6 0.6 0.3 0.1
Systolic Blood Pressure 0.2 0.8 2.8 -0.3 -0.2 -0.4 -1.7 -1.3 0.2 0.1 -1.4 -0.5
Smoking Status 0.5 1.1 3.0 -0.4 -1.5 1.4 1.7 -0.5 -0.7 -1.1 -0.5 0.2
Allergy or Eczema 0.2 0.5 1.7 0.6 1.3 0.0 -1.2 0.0 0.8 -0.1 0.2 -0.3
Cardiovascular Disease 0.4 1.2 2.8 -0.7 0.1 -0.9 -1.1 -1.3 1.7 1.4 -1.4 -0.3
Hypothyroidism (self reported) 2.1 4.8 8.8 2.2 1.7 -2.2 -2.9 1.5 2.5 3.0 1.3 1.9
Respiratory disease 0.1 0.3 1.2 0.3 1.1 -0.3 -0.7 -0.0 0.4 0.1 0.2 -0.5
Type 2 Diabetes (T2D) (2018) 1.3 2.4 5.9 2.4 2.0 0.2 1.0 1.9 0.2 1.0 1.6 1.9
Lung FEV1/FVC ratio 0.1 0.4 0.9 -0.2 1.0 0.4 -0.4 0.1 -1.0 -0.8 -0.2 0.7
Lung FVC 0.3 1.3 5.4 1.3 1.2 0.2 2.3 0.5 0.1 -0.4 1.1 -1.1
Neuroticism 0.1 0.3 0.4 -0.6 0.4 0.6 0.6 -0.5 -0.2 -0.6 -0.1 -0.6
Chronotype (morning person) 0.6 1.3 3.8 -0.8 -1.9 -1.6 -1.1 0.1 1.4 1.2 0.2 0.4
Hair Pigment 0.1 3.3 10.5 -0.2 0.6 -2.0 -3.2 0.5 2.5 2.5 1.0 0.5
Tanning 0.2 2.1 7.2 0.7 0.4 1.1 2.7 1.0 -2.1 -2.0 0.7 0.3
Hand grip strength (left) 0.3 0.7 2.1 1.3 -1.4 -0.2 -0.5 0.6 0.7 0.5 0.6 0.6
Number of treatments/medications taken 0.8 1.4 3.2 -1.7 1.8 0.6 -0.1 -1.2 -0.6 -1.0 -1.5 -1.2
Average weekly spirits intake 0.4 0.5 1.7 -0.9 0.6 -0.9 -1.3 -0.6 0.3 0.4 -0.6 -0.6
Sensitivity / hurt feelings 0.2 0.3 1.6 -0.4 1.2 0.4 -0.6 0.4 0.4 -0.2 0.5 -0.3
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.2 -1.1 1.1 -0.3 0.3 -0.5 -0.5 -0.5 -0.5 -0.7
Hearing difficulty/problems: Yes 1.0 1.6 3.1 0.1 1.5 1.4 1.7 0.2 -1.8 -1.7 0.3 1.1
Relative age of first facial hair 0.3 0.6 1.6 -0.1 1.1 -0.0 -0.5 -1.0 -0.7 -0.7 -0.7 -1.2
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 3.0 -0.5 1.7 -0.4 -1.3 -0.1 0.5 0.3 -0.1 -0.4
Ever used hormone-replacement therapy (HRT) 0.1 0.1 0.4 0.1 0.6 0.1 -0.3 -0.3 -0.2 0.2 -0.6 -0.1
Ever had hysterectomy (womb removed) 0.3 0.4 1.3 -0.6 0.0 -0.5 -1.1 -0.6 0.4 0.8 -0.5 -0.3
Systolic blood pressure, automated reading 0.3 1.0 5.1 -0.0 1.0 -0.8 -2.2 -0.3 0.5 0.9 -0.5 0.8
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 4.0 1.2 2.0 0.3 0.3 0.6 -0.7 -0.1 0.5 0.4
Angina 0.1 0.2 1.3 -0.5 0.2 0.1 0.2 -0.1 -0.1 0.1 -0.1 -1.1
Medication for hormone replacement therapy 0.3 0.3 1.5 0.9 1.2 -0.5 -0.2 0.5 -0.2 0.3 -0.1 -0.2
Vitamin and mineral supplements 0.4 0.5 2.1 1.2 -1.5 0.5 0.7 0.3 -0.1 0.2 0.3 0.3
Supplements: Zinc 0.9 1.0 3.2 0.8 1.8 -0.7 -0.1 1.3 0.7 0.9 0.9 0.9
Medication: Co-codamol 2.1 2.4 5.7 -2.1 1.8 -0.5 -0.6 -2.3 -0.1 -0.4 -2.4 -1.6
Medication: Metformin 1.1 1.6 4.0 1.7 0.3 0.7 1.3 2.0 -0.2 0.7 1.6 1.3
Diabetes (father) 0.1 0.1 0.3 0.0 -0.3 -0.0 0.5 0.4 -0.0 -0.1 0.4 0.1
Diabetes (mother) 0.3 0.3 1.3 -0.6 -0.4 0.3 0.1 -0.4 -1.2 -1.0 0.1 -0.0
Severe depression (siblings) 0.6 0.7 1.7 -1.1 0.8 -1.3 -0.3 0.0 1.1 0.9 -0.2 -0.5
Pack years adult smoking proportion 0.2 0.3 0.9 -0.5 0.5 0.2 0.6 -0.6 -0.3 -0.0 -0.2 -1.0
Impedance of leg (right) 0.0 0.1 0.5 0.4 0.5 0.1 -0.7 0.0 -0.0 -0.5 0.0 -0.0
Leg fat-free mass (left) 0.2 0.8 3.2 -0.2 1.5 -0.2 -1.8 0.2 0.2 0.6 -0.0 1.2
Trunk fat percentage 0.6 2.3 10.8 0.9 3.3 1.2 -0.7 1.1 -0.6 -0.4 0.8 2.2
Hand grip strength (right) 0.4 1.1 3.5 1.1 -0.7 -0.9 -1.9 0.4 1.1 1.0 0.6 1.0
Townsend deprivation index at recruitment 0.3 0.4 1.7 -0.5 -1.3 0.2 0.5 0.4 -0.6 -0.5 0.3 -0.3
Current tobacco smoking 1.1 1.8 5.5 -0.3 -2.4 1.2 1.9 -0.4 -1.6 -1.5 -0.4 -0.2
Average weekly fortified wine intake 1.4 1.6 4.2 -0.7 2.0 -1.1 -2.0 -1.4 -0.5 -0.2 -1.3 -0.7
Maternal smoking around birth 0.9 1.4 3.2 -1.2 -0.2 -1.7 0.1 -1.8 0.2 0.9 -1.6 -1.1
Fed-up feelings 0.2 0.3 0.9 -1.0 0.4 0.1 0.7 -0.5 -0.3 -0.3 -0.4 -0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.3 1.7 4.6 -0.6 0.8 1.2 1.6 -1.0 -2.1 -1.9 -1.0 -0.4
Relative age voice broke 0.8 1.2 5.3 -1.0 0.4 0.0 0.7 -1.1 -0.7 -1.1 -0.9 -2.3
Taking other prescription medications 1.1 1.7 5.1 -1.1 2.3 1.3 0.0 -0.7 -1.5 -1.7 -1.0 -0.7
Age when periods started (menarche) 1.2 3.0 5.9 -2.4 -0.8 0.2 0.1 -2.3 -1.3 -1.5 -2.4 -2.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.3 0.2 0.4 -0.4 -0.9 0.1 0.4 1.1 -0.4 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.0 -1.0 0.6 -0.6 0.7 -0.5 0.8 0.1 -0.5 -0.4
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 2.8 -1.7 0.5 -0.2 -0.6 -0.8 -0.0 0.0 -1.0 -1.4
Qualifications: CSEs or equivalent 0.1 0.1 0.3 -0.0 0.0 0.2 0.2 -0.4 0.2 -0.2 -0.5 0.4
Serious illness, injury or assault to yourself 1.0 1.2 2.7 0.8 1.6 0.9 0.4 1.5 -1.0 -0.8 1.3 1.1
High blood pressure 0.2 0.6 2.4 -0.5 0.4 0.2 -0.6 -1.3 0.2 0.3 -1.6 -0.5
Hayfever, allergic rhinitis or eczema 0.4 0.9 3.6 1.0 1.9 -0.2 -1.3 0.3 1.2 0.2 0.2 -0.2
Multivitamins +/- minerals 1.1 1.4 4.6 -1.4 2.2 -1.5 -0.8 -0.9 0.6 0.4 -0.7 -1.1
Stomach or abdominal pain in last month 1.2 1.5 4.0 0.2 1.9 1.1 1.6 0.3 -2.0 -1.5 0.2 -0.0
Supplements: Glucosamine 1.7 2.2 5.2 -1.0 2.2 2.2 0.2 -0.9 -1.6 -2.3 -0.8 -0.4
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 4.8 0.6 2.1 -0.3 -1.9 1.2 1.1 1.2 1.4 2.2
Medication: Atenolol 1.9 2.4 6.5 -2.5 1.1 -0.8 -1.4 -1.9 1.0 0.7 -1.3 -2.1
Medication: Levothyroxine sodium 2.2 3.7 8.9 0.9 2.1 -2.5 -2.4 0.6 2.4 3.0 0.4 0.8
Sitting height 0.2 1.1 5.5 -1.1 0.5 0.3 -2.4 -1.0 -0.6 -0.8 -0.9 0.4
Chronic bronchitis/emphysema (father) 4.7 5.5 9.1 2.0 -0.1 2.7 2.5 2.3 -2.9 -2.3 2.0 3.0
High blood pressure (mother) 0.4 0.6 2.9 -0.2 -1.7 -0.1 0.2 -0.6 0.2 0.4 -0.7 -1.2
Body mass index (BMI) 0.3 1.4 4.4 1.2 2.1 0.2 -0.2 1.1 0.4 1.0 0.9 1.8
Impedance of leg (left) 0.0 0.1 0.3 0.5 -0.4 -0.1 -0.5 0.0 -0.0 -0.4 0.1 -0.3
Leg predicted mass (left) 0.2 0.9 3.3 -0.1 1.5 -0.2 -1.8 0.2 0.2 0.7 0.0 1.3
Trunk fat mass 0.5 2.3 10.3 0.8 3.2 0.8 -1.4 1.0 -0.3 0.1 0.7 2.3
Waist circumference 0.4 1.6 2.7 1.1 1.6 -0.4 -1.5 1.3 1.1 1.6 0.9 1.6
Number of incorrect matches in round 0.4 0.6 1.8 -1.0 0.4 -0.7 -1.4 -1.0 0.5 0.5 -0.9 -0.0
Past tobacco smoking 0.1 0.2 0.9 0.5 0.1 -0.9 -0.6 -0.1 0.4 0.4 0.3 -0.4
Alcohol usually taken with meals 0.6 1.0 2.7 1.0 0.2 -0.9 -1.3 0.2 1.5 1.6 0.3 0.6
Nervous feelings 0.3 0.6 2.5 -1.6 -0.3 0.5 0.4 -0.3 -0.7 -1.1 -0.2 -0.8
Frequency of tenseness / restlessness in last 2 weeks 1.3 1.9 4.6 -1.1 0.8 1.1 2.1 -0.8 -1.9 -2.0 -0.8 -1.0
Hearing difficulty/problems with background noise 1.1 1.7 7.4 0.7 2.7 1.1 1.1 0.9 -1.0 -1.2 1.0 1.0
Hair/balding pattern: Pattern 2 0.3 0.3 1.0 -0.8 -0.5 -0.3 0.1 -0.8 0.2 0.1 -0.5 -1.0
Had menopause 0.1 0.2 0.8 -0.6 0.2 -0.2 -0.9 -0.2 -0.4 -0.1 -0.1 -0.2
Had other major operations 1.4 1.7 3.6 0.9 1.1 -0.3 -1.9 1.5 1.1 0.8 1.4 1.8
Forced vital capacity (FVC) 0.2 0.6 1.4 0.3 1.1 -0.9 -1.2 -0.3 1.1 0.6 -0.1 -0.1
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 2.7 -1.6 0.3 -0.2 1.5 -1.5 0.2 -0.7 -1.7 -1.3
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.7 1.3 0.9 0.9 -0.1 1.0 0.3 0.2 0.7 0.6
Qualifications: None of the above 0.3 0.7 2.6 -0.6 1.3 0.1 0.6 -0.4 -0.0 0.1 -1.1 -1.6
Financial difficulties in last 2 years 0.2 0.3 2.0 0.1 1.4 0.1 0.4 -0.2 -0.3 -0.2 -0.1 0.7
Mouth/teeth dental problems 0.6 1.0 3.5 0.9 1.9 -0.2 -1.0 -0.5 0.5 0.3 -0.3 -1.7
Heart attack 1.2 1.5 6.0 -1.7 2.4 -0.5 -0.3 -1.1 1.0 0.6 -0.9 -1.1
Allergy 0.1 0.3 0.7 -0.5 -0.4 -0.0 0.9 -0.4 -0.8 -0.0 -0.4 0.6
Pain all over the body in last month 0.1 0.2 0.4 0.3 -0.3 0.1 0.6 0.4 -0.4 0.2 0.5 -0.4
Diabetes (self-reported) 3.8 5.9 9.9 2.8 1.5 2.1 2.9 3.1 -1.8 -0.6 2.9 2.7
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.3 -0.4 0.9 -0.8 -1.2 -0.5 0.2 -0.3 -0.2 -0.9
Medication: Ramipril 0.3 0.4 1.5 0.2 -0.1 0.5 1.2 -0.7 -0.3 -0.3 -0.9 0.6
Medication: Simvastatin 0.2 0.3 0.7 0.4 -0.2 -0.1 -0.1 0.8 0.8 0.8 0.8 0.2
Fluid intelligence score 0.4 0.8 2.7 0.3 -0.4 -1.3 -0.7 0.1 1.7 1.5 0.2 -0.2
Illnesses of siblings 0.9 1.3 3.9 -0.4 1.4 -1.8 -2.0 -0.6 0.7 1.2 -0.7 0.2
Neuroticism score 0.3 0.7 1.8 -1.4 1.2 0.4 0.4 -0.7 -0.3 -1.0 -0.4 -1.1
Weight 0.4 1.8 5.2 0.6 2.3 -0.2 -2.2 0.8 0.4 1.0 0.5 2.0
Impedance of arm (right) 0.2 0.9 3.0 -0.1 0.7 1.4 -0.5 -0.2 -1.3 -1.7 -0.3 0.1
Arm fat percentage (right) 0.5 2.0 7.8 1.4 2.8 1.0 -0.4 1.2 -0.2 0.2 0.9 2.1
Trunk fat-free mass 0.2 1.3 7.1 -0.3 0.5 -1.2 -2.7 0.0 0.9 1.4 0.0 0.6
Hip circumference 0.7 2.8 9.8 0.4 2.7 -1.1 -3.1 0.3 1.4 1.9 0.2 1.2
Time employed in main current job 1.4 1.6 7.0 -0.5 -2.6 0.9 1.5 -0.1 -1.4 -1.4 0.3 -0.3
Alcohol intake versus 10 years previously 1.0 1.5 3.4 1.6 -0.0 1.8 1.4 1.1 0.7 0.1 0.9 1.8
Father’s age at death 1.2 1.6 3.5 -1.8 1.9 -0.2 -0.3 -1.3 -1.4 -1.4 -1.2 -0.8
Worrier / anxious feelings 0.6 1.2 3.6 -1.9 -0.2 -1.1 0.5 -1.1 0.1 -0.1 -1.1 -1.7
Frequency of tiredness / lethargy in last 2 weeks 1.2 2.0 6.4 1.1 1.0 1.9 2.5 1.0 -1.1 -1.2 1.1 1.0
Falls in the last year 0.9 1.2 2.5 1.6 1.4 0.7 0.1 1.2 0.7 0.4 1.1 1.4
Hair/balding pattern: Pattern 3 0.4 0.6 1.5 -0.8 0.9 -0.5 -0.1 -0.8 0.7 0.5 -1.2 -0.5
Number of live births 0.4 0.6 1.8 -0.6 -0.9 0.1 0.6 0.1 -1.4 -1.3 0.1 0.0
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.7 0.8 1.6 -0.7 -1.0 0.1 1.1 0.5 0.3 0.4
Pulse rate 0.6 1.0 2.8 1.1 -1.0 -0.5 0.2 0.2 1.5 1.7 -0.0 1.2
Happiness 0.1 0.1 0.6 -0.8 0.1 -0.2 -0.4 -0.4 0.3 0.1 -0.2 -0.2
Noisy workplace 0.1 0.1 0.5 -0.0 -0.7 0.1 0.6 0.1 -0.4 0.0 0.3 0.5
Qualifications: A levels/AS levels or equivalent 0.3 0.7 1.6 0.6 0.7 0.4 -1.0 0.9 0.5 0.5 1.2 1.3
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.4 0.4 -0.9 -0.1 0.5 0.9 0.0 0.2 1.2 0.4
Mouth/teeth dental problems: Dentures 0.2 0.3 0.9 -0.1 -0.7 0.4 0.3 1.0 -0.1 0.1 0.8 0.8
Asthma 0.3 0.5 2.5 0.7 1.6 0.4 -0.3 0.6 0.1 -0.3 1.1 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.1 -0.6 0.7 0.4 1.0 -0.1 -0.1 -0.3 -0.3 -0.3
Medication: Cholesterol lowering 0.9 1.5 4.2 0.1 -1.2 2.0 1.6 0.6 -1.4 -1.6 0.3 0.4
Depression (self-reported) 0.7 0.9 2.0 0.6 0.6 -0.0 -0.2 1.2 1.3 1.2 0.8 1.4
Medication: Lansoprazole 0.8 0.9 2.2 -1.1 1.5 -0.8 -0.6 -0.7 0.9 0.7 -0.6 -1.0
Prospective memory result 1.2 1.4 3.0 -1.2 -0.3 0.6 0.4 -1.1 -1.7 -1.4 -1.2 -1.7
Lung cancer (father) 1.0 1.2 2.8 1.4 -0.5 1.3 1.2 1.3 -0.5 -0.4 0.7 1.7
Illnesses of mother 0.2 0.2 0.9 0.9 0.1 0.1 0.5 0.5 -0.0 0.1 -0.1 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 1.3 1.1 0.9 0.1 -0.4 0.5 0.0 -0.3 0.6 0.3
Pulse wave Arterial Stiffness index 0.2 0.3 1.0 -0.4 -1.0 -0.5 -0.4 0.2 0.1 0.5 0.5 0.5
Impedance of arm (left) 0.1 0.4 1.6 -0.1 0.3 0.9 -0.5 -0.1 -0.7 -1.3 -0.2 0.1
Arm fat mass (right) 0.4 1.6 6.6 1.0 2.6 0.7 -0.9 0.9 -0.3 0.3 0.7 1.9
Trunk predicted mass 0.2 1.3 6.8 -0.3 0.4 -1.2 -2.6 0.1 0.9 1.4 0.1 0.6
Standing height 0.3 2.6 19.9 -1.2 0.6 -0.7 -4.5 -0.6 0.1 0.1 -0.7 0.5
Length of working week for main job 0.7 0.8 3.2 -0.9 -1.8 -0.3 -0.7 -0.6 -0.5 -0.7 -1.0 -0.4
Exposure to tobacco smoke at home 0.5 0.5 1.1 0.0 -0.1 -0.9 -1.1 -0.2 1.0 1.0 -0.8 -0.3
Breastfed as a baby 1.3 1.6 6.1 -1.1 2.5 -1.2 -1.8 -1.2 0.5 0.3 -1.1 -0.0
Tense / ‘highly strung’ 0.3 0.6 2.3 -0.2 -0.1 1.5 0.8 -0.3 -0.5 -1.2 -0.1 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.9 0.3 0.5 0.9 0.9 0.1 -0.8 -0.6 0.5 0.1
Hair/balding pattern: Pattern 4 0.7 1.8 4.6 0.5 -0.8 1.5 2.1 0.8 -1.9 -1.8 1.0 0.4
Birth weight of first child 0.1 0.2 1.0 -0.9 -1.0 0.1 0.4 0.2 -0.1 0.0 0.3 -0.1
Peak expiratory flow (PEF) 1.3 3.0 6.3 1.6 1.8 -1.2 -2.3 1.3 2.5 2.1 1.3 1.0
Pulse wave reflection index 0.7 0.8 2.4 -1.3 -0.0 0.5 0.6 -0.6 -1.5 -1.5 -0.5 0.2
Ever highly irritable/argumentative for 2 days 0.9 1.1 2.7 0.3 1.2 1.6 1.2 0.4 -0.9 -1.6 0.3 0.6
Loud music exposure frequency 0.7 0.8 2.5 1.6 1.3 0.6 0.6 0.4 0.4 0.3 0.2 1.3
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.3 0.5 -0.8 0.5 -0.5 0.5 -0.0 -0.1 1.1 0.2
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 2.8 0.6 -1.1 0.6 1.4 1.7 -1.1 -0.4 1.4 1.5
Blood clot in the leg (DVT) 0.3 0.3 1.3 0.2 -0.3 1.1 -0.1 0.8 0.0 -0.4 0.7 0.4
Medication: Paracetamol 1.2 2.0 3.5 -1.5 1.1 -1.7 -1.0 -1.5 1.3 1.1 -1.5 -1.9
Headache pain in last month 1.5 2.6 5.3 -1.8 1.7 0.1 1.8 -1.4 -1.7 -1.7 -1.1 -2.3
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 4.3 -0.2 1.2 -2.1 -1.1 -0.2 1.1 1.3 -0.0 -0.2
Glaucoma (self-reported) 1.3 1.5 4.7 1.4 -0.7 2.2 1.6 1.1 -0.9 -0.7 1.1 0.6
Gout (self-reported) 1.5 2.1 4.8 -1.4 -1.5 0.7 1.1 -2.0 -1.0 -1.2 -2.2 -1.2
Hypothyroidism/myxoedema (self-reported) 1.8 3.4 6.4 1.7 2.2 -1.4 -2.5 1.6 1.7 2.1 1.5 1.8
Medication: Amlodipine 0.3 0.4 2.6 -0.3 1.6 -0.1 -0.6 -0.3 0.6 0.4 -0.3 -0.1
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.6 0.2 -0.2 0.8 -0.3 0.1 0.3 -0.3 0.3 -0.6
Birth weight 0.6 1.3 5.3 -1.1 -2.3 0.0 0.5 0.8 -0.8 -0.5 0.8 1.7
Chronic bronchitis/emphysema (mother) 0.9 1.1 3.4 -0.1 1.8 -1.3 -1.4 -0.8 0.9 0.8 -0.4 -0.5
High blood pressure (siblings) 1.2 1.8 5.9 -0.3 -2.4 1.7 1.6 -0.8 -1.2 -1.2 -0.5 -1.0
Forced vital capacity (FVC), Best measure 0.1 0.3 1.0 0.6 0.8 -0.5 -1.0 0.0 0.4 0.1 0.2 -0.0
Body fat percentage 0.5 1.8 9.1 0.9 3.0 1.0 -0.6 0.8 -0.3 -0.1 0.5 2.0
Leg fat percentage (right) 0.5 1.7 5.7 1.3 2.4 0.8 -0.2 1.3 0.1 0.3 1.0 2.1
Arm fat-free mass (right) 0.2 1.2 4.7 -0.1 0.7 -1.3 -2.2 0.1 1.1 1.6 -0.0 0.7
Exposure to tobacco smoke outside home 0.3 0.4 1.2 1.0 1.1 0.5 0.7 0.2 -0.6 -0.4 0.1 0.2
Comparative body size at age 10 0.1 0.2 1.6 0.3 -0.3 -0.0 0.4 0.0 -0.1 0.4 -0.2 1.3
Number of full brothers 2.7 3.4 9.0 -1.6 0.6 -3.0 -1.5 0.1 2.7 2.2 0.1 -2.0
Worry too long after embarrassment 0.5 0.9 4.2 -1.2 2.1 0.0 -0.3 -0.3 -0.3 -1.1 -0.2 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.4 2.6 1.1 1.1 1.1 1.5 1.4 -0.7 -0.6 1.1 1.6
Wheeze or whistling in the chest in last year 1.3 2.3 13.7 0.8 3.7 1.3 0.6 0.8 -0.3 -0.7 1.1 1.3
Number of children fathered 0.9 1.1 2.7 -1.5 -0.2 -0.7 -0.9 -1.6 0.1 -0.2 -1.6 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 2.5 -1.2 1.2 -1.4 -1.6 -1.6 1.3 1.0 -1.3 -0.4
Age at first live birth 0.3 0.5 2.5 0.4 0.7 0.8 1.6 0.1 -0.1 -0.7 0.4 0.4
Pulse wave peak to peak time 0.2 0.2 1.0 0.4 1.0 0.2 -0.0 -0.2 0.0 -0.3 -0.5 -0.4
Health satisfaction 0.5 0.6 1.7 -1.3 0.8 1.0 -0.0 -0.0 -0.4 -1.3 0.1 -0.1
Shortness of breath walking on level ground 0.3 0.3 1.0 -0.3 0.7 0.8 1.0 -0.4 -0.4 -0.5 -0.0 -0.5
Qualifications: College or University degree 0.1 0.2 0.5 0.0 0.7 0.3 -0.6 -0.5 0.0 -0.3 -0.2 -0.3
Eye problems/disorders: None of the above 1.2 1.4 3.2 -1.2 -1.0 -1.6 0.1 -1.6 0.4 0.4 -1.8 -1.1
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.0 -0.8 -0.2 -0.8 -0.6 -0.8 -0.0 0.4 -1.0 0.0
Emphysema/chronic bronchitis 0.3 0.3 1.8 -0.4 -1.3 -0.4 0.5 -0.2 0.3 0.2 -0.4 -0.6
Medication for pain relief, constipation, heartburn 1.0 1.7 4.1 1.8 -0.5 1.1 0.5 1.4 -1.0 -1.0 1.6 2.0
Neck or shoulder pain in last month 1.0 1.5 3.2 -1.4 0.8 -0.1 1.8 -1.5 -0.5 -0.8 -1.5 -1.4
Medication: Blood pressure 0.2 0.3 2.0 0.1 0.2 1.4 -0.0 -0.1 0.1 -0.3 -0.4 0.4
Angina (self-reported) 0.1 0.2 1.3 -0.4 0.2 -0.1 0.0 -0.0 0.3 0.5 -0.1 -1.1
Migraine (self-reported) 1.1 1.3 4.5 -1.4 -0.3 -1.0 1.1 -1.2 0.1 -0.1 -1.3 -2.1
Medication: Ibuprofen 0.7 0.8 2.4 -0.7 1.5 0.7 1.3 -0.6 -0.5 -0.8 -0.9 -0.1
Medication: Allopurinol 0.4 0.5 1.8 -0.6 -0.8 0.1 0.5 -1.2 -0.5 -0.3 -1.3 -0.4
Medication: Omeprazole 0.8 0.9 4.8 -0.7 -2.2 0.2 0.9 -0.6 -1.0 -0.4 -0.8 -0.1
Medication: Seretide 50 evohaler 1.1 1.3 4.5 -1.1 -1.0 -0.6 0.3 -1.5 -0.3 -0.3 -1.3 -2.1
Mean time to correctly identify matches 1.5 2.8 7.9 -0.2 -0.9 -1.7 -2.8 0.4 2.3 2.8 0.6 -0.7
Heart disease (mother) 0.8 1.0 1.8 1.2 -1.0 -0.3 -0.4 1.0 0.8 1.3 1.1 1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.5 -1.1 -0.3 0.2 1.0 -0.5 -0.0 -1.0 -0.3 -1.2
Whole body fat mass 0.4 1.8 8.6 0.8 2.9 0.6 -1.2 0.8 -0.3 0.1 0.6 2.0
Leg fat mass (right) 0.6 2.1 8.2 1.4 2.9 0.8 -0.7 1.3 -0.1 0.3 1.0 2.3
Arm predicted mass (right) 0.2 1.1 4.6 -0.4 0.6 -1.3 -2.1 -0.3 0.9 1.4 -0.3 0.4
Pulse rate, automated reading 1.0 3.1 11.6 0.1 -2.8 2.0 3.4 -0.2 -1.6 -1.4 -0.2 0.0
Alcohol intake frequency. 1.9 4.4 8.0 1.5 1.1 2.8 2.7 2.5 -2.0 -1.4 1.9 2.2
Comparative height size at age 10 0.1 0.7 4.9 -0.0 0.5 0.1 -2.2 0.7 -0.6 -0.4 0.4 0.6
Number of full sisters 0.1 0.2 0.5 -0.2 0.7 0.5 0.3 -0.2 0.0 -0.5 -0.5 -0.4
Suffer from ‘nerves’ 0.9 1.4 4.2 -0.6 -1.0 1.5 2.1 -0.3 -1.1 -1.7 -0.1 -0.9
Overall health rating 0.3 0.6 2.7 -0.4 1.6 -0.7 0.5 0.2 1.0 0.9 -0.2 -0.1
Chest pain or discomfort 1.5 2.2 4.0 1.4 1.9 1.9 1.6 1.1 -0.8 -1.0 1.1 2.0
Had major operations 0.7 0.8 4.1 -0.3 2.0 -0.5 -0.7 -0.7 -0.4 -0.5 -0.7 -0.9
Age at last live birth 0.9 1.3 4.1 -0.8 0.8 0.6 2.0 -0.6 -1.4 -1.9 -0.1 -0.5
Family relationship satisfaction 0.4 0.5 1.6 -0.1 -0.3 -0.5 -1.2 0.2 1.0 0.8 0.4 0.9
Leg pain on walking 0.4 0.4 1.3 -0.1 -1.1 0.4 1.1 0.1 -0.0 -0.1 0.3 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 2.6 1.3 -1.0 0.4 0.9 1.3 -0.3 0.2 1.4 1.6
Commuting to job workplace: Car/motor vehicle 1.6 1.8 5.2 -1.7 0.4 -0.6 0.4 -2.3 -0.6 -0.5 -2.1 -1.7
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 2.3 -0.5 -0.8 -0.4 -0.9 -1.3 0.5 0.2 -1.5 -0.2
Medication: Aspirin 1.3 1.7 7.9 -1.7 -0.5 -0.0 0.3 -1.3 -0.1 -0.3 -1.4 -2.8
Supplements: Vitamin C 0.3 0.4 1.0 -0.7 -1.0 0.3 1.0 0.3 0.4 0.0 0.4 -0.7
Knee pain experienced in last month 0.7 1.1 4.4 -0.1 0.3 2.1 1.2 -0.0 -1.0 -1.5 -0.1 0.6
Hypertension (Self-reported) 0.3 0.8 2.8 -0.5 0.1 -0.0 -0.9 -1.4 0.7 0.9 -1.7 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.9 2.9 -1.3 0.5 -0.6 -0.3 -1.4 0.2 0.2 -1.7 -0.7
Illnesses of father: Heart disease 2.5 3.5 10.4 -0.8 -0.5 -3.2 -1.9 -1.6 2.0 2.5 -1.7 -1.1
Illnesses of siblings: Diabetes 2.1 2.5 4.4 1.6 -0.5 1.7 2.1 2.1 -0.5 -0.9 2.1 1.7
Smoking status: Previous 0.1 0.1 0.5 -0.4 0.3 0.5 0.1 0.2 0.2 0.1 0.0 0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.7 2.4 -1.0 0.3 -0.1 -1.5 -1.4 -0.0 -0.2 -1.0 -0.2
Whole body fat-free mass 0.2 1.1 5.5 -0.2 0.8 -1.0 -2.3 0.1 0.7 1.3 0.0 0.8
Leg fat-free mass (right) 0.1 0.6 2.7 -0.2 0.9 -0.5 -1.6 0.1 0.2 0.7 -0.1 0.9
Arm fat percentage (left) 0.5 2.2 7.0 1.5 2.6 1.2 -0.2 1.4 -0.3 0.1 1.1 2.4
Average weekly red wine intake 0.4 0.6 1.2 -0.8 1.1 -0.2 -0.9 -0.9 -0.5 -0.6 -0.6 -0.8
Handedness (chirality/laterality): Left-handed 1.0 1.2 2.6 0.2 1.2 1.3 -0.1 -0.4 -1.4 -1.6 -0.7 1.4
Mood swings 0.1 0.1 0.4 0.4 -0.5 0.6 0.2 0.3 0.4 0.2 0.3 -0.2
Loneliness, isolation 1.8 2.5 8.8 -1.5 -0.7 -1.6 -0.3 -1.4 1.6 1.4 -1.4 -3.0
Long-standing illness, disability or infirmity 1.1 1.7 6.1 1.2 2.5 0.0 -0.2 1.5 0.6 0.6 1.5 1.6
Ever had bowel cancer screening 0.7 0.8 2.0 -0.9 0.3 -1.0 -1.4 0.1 1.4 0.9 -0.0 -0.8
Diabetes diagnosed by doctor 2.0 3.4 7.7 2.4 1.9 0.6 1.5 2.8 -0.3 0.7 2.5 2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.7 -0.0 0.6 -0.7 0.8 -0.1 0.2 -0.0 0.1 0.2
Friendships satisfaction 0.9 1.1 7.3 -1.1 -2.7 -0.6 0.2 -0.6 0.2 0.3 -0.9 -0.3
Qualifications: nursing, teaching 1.2 1.8 3.2 1.6 0.6 1.6 0.2 1.7 -0.7 -1.1 1.8 1.7
Commuting to job workplace: Walk 0.2 0.3 0.8 0.5 -0.3 0.9 0.5 0.4 -0.0 -0.4 0.4 -0.7
Eye problems/disorders: Cataract 0.8 0.9 2.7 0.8 0.0 1.3 -0.6 1.5 0.0 -0.1 1.6 0.5
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 1.5 -1.2 0.3 -0.5 -0.2 -0.4 0.5 0.0 -0.0 0.8
Medication for cholesterol 0.1 0.2 1.5 -0.0 -1.2 0.0 0.2 -0.4 0.0 -0.5 0.1 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.7 -0.5 1.0 -0.5 -1.3 -0.2 0.5 0.3 -0.1 -0.1
Back pain experienced in last month 0.4 0.6 1.3 -0.6 -0.6 1.0 1.0 0.0 -0.9 -1.1 -0.1 -0.5
Mineral and other dietary supplements 0.8 1.1 3.7 1.0 -1.9 -0.8 0.6 0.9 0.5 1.3 1.0 0.7
Breast cancer (self-reported) 0.6 0.7 1.4 -0.6 0.7 -1.2 -0.7 0.8 1.2 0.9 0.4 -0.6
Asthma (self-reported) 0.2 0.3 1.5 0.3 1.2 0.4 -0.3 0.4 0.1 -0.3 0.9 -0.3
Osteoporosis (self-reported) 1.0 1.2 3.4 -0.9 1.8 0.9 -0.9 -1.0 -0.7 -1.4 -0.7 -0.9
Osteoarthritis (self-reported) 0.5 0.7 1.7 -1.3 1.0 -0.0 0.2 -0.9 0.1 -0.1 -1.3 -1.0
Medication: Aspirin 1.0 1.3 5.6 -1.4 -0.4 0.3 0.6 -1.2 -0.1 -0.4 -1.3 -2.4
Medication: Gliclazide 1.6 1.8 3.3 1.5 -1.8 0.3 1.8 1.3 1.1 1.4 1.0 1.4
Illnesses of father: None of the above (group 1) 0.1 0.1 0.5 -0.3 0.7 0.4 -0.3 0.2 0.1 -0.3 0.2 0.1
Smoking status: Current 1.1 1.7 4.5 -0.1 -1.9 1.3 2.1 -0.4 -1.7 -1.6 -0.4 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 2.8 -0.4 0.9 -1.2 -0.1 -1.0 1.1 0.5 -1.0 -1.7
Whole body water mass 0.2 1.1 5.8 -0.3 0.8 -0.9 -2.4 -0.0 0.7 1.2 -0.1 0.7
Leg predicted mass (right) 0.1 0.6 2.8 -0.3 0.8 -0.5 -1.7 -0.0 0.3 0.8 -0.1 0.9
Arm fat mass (left) 0.5 2.1 6.7 1.5 2.6 0.8 -0.7 1.4 -0.3 0.3 1.2 2.4
Number of self-reported non-cancer illnesses 0.5 0.9 4.1 -1.2 2.0 0.1 -0.9 -0.4 0.6 0.3 -0.6 -0.8
Average weekly champagne plus white wine intake 0.7 0.9 2.6 0.9 -1.3 1.6 1.0 0.2 -1.2 -0.9 -0.1 0.5
Miserableness 0.2 0.4 1.5 0.1 0.5 0.7 1.2 0.0 -0.8 -0.8 -0.1 -0.4
Guilty feelings 0.2 0.3 1.4 -0.7 0.3 0.4 -1.2 -0.5 -0.5 -0.5 -0.1 -0.3
Wears glasses or contact lenses 0.1 0.1 0.5 0.2 -0.0 0.5 0.7 0.4 0.1 -0.1 0.3 -0.2
Ever taken oral contraceptive pill 1.2 1.3 3.2 -1.4 -1.8 0.5 1.8 -0.9 -0.9 -1.0 -0.6 -0.5
Hearing aid user 0.4 0.5 2.5 -0.4 -1.6 -0.8 0.2 0.2 0.2 0.4 0.2 -0.8
Mother’s age at death 0.9 1.1 3.0 0.0 0.7 -0.9 -1.4 0.2 1.7 1.7 -0.1 0.9
Financial situation satisfaction 1.4 1.7 3.6 -1.4 1.3 -1.8 -1.9 -0.8 1.3 1.3 -0.7 0.5
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.2 0.4 -0.2 0.5 0.4 0.5 -0.1 -0.4 0.1 1.1
Commuting to job workplace: Public transport 1.8 2.1 4.4 1.3 -0.3 -1.0 -1.0 2.1 1.9 1.6 2.0 0.7
Eye problems/disorders: Glaucoma 0.8 1.0 2.6 1.1 -1.3 1.6 0.7 0.9 -0.7 -0.6 0.9 0.3
Medication: Blood pressure 0.3 0.6 2.4 -1.5 0.3 0.3 -0.2 -1.0 -0.6 -0.3 -1.1 -0.7
Pain type(s) experienced in last month: Hip pain 1.9 2.4 6.7 0.7 0.2 2.6 1.5 1.5 -1.8 -2.2 1.0 0.9
Supplements: Fish oil (including cod liver oil) 0.9 1.2 5.0 -1.1 2.2 -0.6 -1.0 -0.9 0.2 -0.2 -1.2 -0.9
High cholesterol (Self-reported) 0.6 1.0 3.2 0.4 -0.5 0.6 1.2 1.6 0.2 0.1 1.8 0.9
Medication: Bendroflumethiazide 0.9 1.4 3.5 -1.9 -0.1 1.4 0.6 -0.8 -1.7 -1.6 -0.9 -0.6
Medication: Paracetamol 1.6 2.4 5.1 -2.0 1.3 -1.2 -0.8 -2.1 0.6 0.2 -2.1 -2.3
Medication: Lisinopril 1.5 1.9 4.5 1.9 -0.3 1.9 0.1 2.1 0.4 0.2 1.8 1.5
Medication: Atorvastatin 1.9 2.4 7.3 0.5 -0.5 2.1 2.7 1.3 -1.6 -1.4 1.3 0.9
Illnesses of father: High blood pressure 0.8 1.0 2.7 -1.3 -0.4 -0.7 -0.5 -1.6 1.3 0.8 -1.1 -0.8
Alcohol drinker status: Never 0.3 0.3 1.2 0.3 -0.3 0.3 -0.3 1.1 -0.1 0.3 0.9 -0.4
Ever smoked 0.3 0.5 1.0 -0.9 -0.5 0.7 0.2 -0.6 -0.6 -0.6 -1.0 -0.4
Basal metabolic rate 0.2 1.1 5.3 -0.0 1.3 -0.7 -2.3 0.2 0.5 1.1 0.1 1.1
Leg fat percentage (left) 0.3 1.2 3.6 1.1 1.9 0.5 -0.2 1.1 0.1 0.4 0.8 1.9
Arm fat-free mass (left) 0.3 1.3 5.6 -0.3 0.9 -1.3 -2.4 -0.2 1.0 1.5 -0.2 0.4
Number of operations (self-reported) 1.1 1.7 4.0 1.0 2.0 -0.4 -1.8 1.4 0.7 0.6 1.2 1.6
Average weekly beer plus cider intake 0.3 0.4 0.9 0.5 -0.7 0.7 0.9 0.2 -0.5 -0.9 0.1 0.2
Irritability 0.1 0.2 0.8 -0.6 0.1 -0.1 0.2 -0.9 0.4 0.2 -0.6 -0.1
Risk taking 1.1 1.6 8.0 -0.6 -2.8 1.1 1.3 -0.6 -0.9 -1.2 -0.5 -0.0
Ever had prostate specific antigen (PSA) test 2.6 3.0 6.9 -2.2 0.2 0.3 -0.2 -1.9 -1.9 -1.9 -2.0 -2.6
Fractured/broken bones in last 5 years 1.1 1.4 3.4 1.1 1.5 1.9 0.8 0.4 -1.1 -1.0 0.3 1.6
Age started oral contraceptive pill 0.3 0.3 1.1 -1.0 0.2 -0.5 -0.2 -0.4 -0.3 -0.4 -0.3 -1.1
Diastolic blood pressure, automated reading 0.4 1.4 3.2 -1.2 0.6 -0.8 -1.8 -1.4 0.5 0.7 -1.7 -1.0
Ever depressed for a whole week 0.7 0.9 1.4 0.8 0.8 1.1 1.2 1.2 -0.7 -0.8 1.2 -0.0
Unable to work because of sickness or disability 0.7 0.9 3.4 1.2 -1.3 0.7 1.8 0.3 -0.8 -0.2 0.6 -0.1
Commuting to job workplace: Cycle 1.0 1.2 2.4 0.7 -0.1 1.5 0.1 1.4 -0.9 -0.9 1.3 1.6
Myopia 0.7 1.1 3.5 0.5 0.6 -1.2 -0.6 0.6 1.8 1.9 0.2 -0.1
Vascular/heart problems diagnosed by doctor 0.4 1.2 3.7 1.1 -0.9 -0.4 0.9 1.7 -0.0 0.1 1.9 1.1
Cholesterol lowering medication 0.7 1.1 2.6 0.8 0.1 -0.6 0.1 1.5 1.2 1.6 1.3 0.8
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.7 -1.0 -1.3 -0.8 0.2 -0.6 0.2 0.6 -0.7 -0.1
Pain experienced in last month 1.9 3.2 9.4 0.6 -0.1 -2.1 -3.1 0.1 2.4 2.7 0.4 1.3
Supplements: Calcium 0.8 0.9 3.0 0.5 1.7 0.6 1.0 1.1 -0.6 -0.9 0.9 -0.4
Basal cell carcinoma (self-reported) 0.8 1.0 4.0 0.8 -0.7 -0.2 -0.2 0.9 0.8 0.9 1.2 2.0
Heart attack/myocardial infarction (self-reported) 1.2 1.5 6.1 -1.7 2.5 -0.4 -0.3 -1.2 0.9 0.5 -1.0 -1.0
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 0.8 0.1 -0.4 0.9 0.1 0.7 0.0 -0.2 0.6 0.2
Heart disease (siblings) 1.5 1.8 6.5 -0.4 -1.0 -1.7 -0.9 0.1 2.5 2.0 0.0 -0.8
Alcohol drinker status: Previous 1.2 1.4 4.0 0.2 -0.2 1.2 1.9 0.7 -2.0 -1.3 0.1 1.0
Pack years of smoking 0.2 0.3 0.9 -0.9 0.7 0.1 0.4 -0.7 -0.4 -0.1 -0.3 -0.9
Impedance of whole body 0.0 0.2 1.4 0.1 0.3 0.6 -0.3 0.1 -0.6 -1.2 0.0 0.1
Leg fat mass (left) 0.4 1.6 6.0 1.1 2.5 0.4 -0.9 1.0 -0.1 0.5 0.7 2.1
Arm predicted mass (left) 0.2 1.2 6.0 -0.3 0.7 -1.1 -2.5 -0.2 0.9 1.3 -0.3 0.5