Hub : Genes

CDK7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0920 0.0290 5.0e-11 0.115 0.102 0.112 0.107 0.120 8.2e-14 2.2e-12 1.6e-13 5.4e-13 2.2e-14
2 GTEx Brain Hypothalamus 0.3070 0.1140 2.6e-03 0.059 NA 0.143 NA 0.017 1.7e-02 NA 3.2e-04 NA 1.3e-01
3 GTEx Cells Transformed fibroblasts 0.1480 0.0410 1.9e-08 0.150 NA 0.131 NA 0.146 2.2e-11 NA 4.7e-10 NA 4.2e-11
4 GTEx Muscle Skeletal 0.0668 0.0291 2.4e-03 -0.002 NA -0.001 NA -0.003 6.9e-01 NA 4.2e-01 NA 7.8e-01
5 YFS Blood 0.0154 0.0095 2.9e-03 0.000 0.006 0.003 0.006 0.001 3.3e-01 3.2e-03 3.0e-02 3.8e-03 1.5e-01
6 TCGA Lung Adenocarcinoma 0.0962 0.0757 2.7e-03 0.004 0.013 0.040 NA 0.012 9.8e-02 9.2e-03 1.6e-05 NA 1.2e-02
7 TCGA Prostate Adenocarcinoma 0.0578 0.0331 3.3e-04 0.017 0.026 0.031 NA 0.028 5.8e-03 8.3e-04 3.4e-04 NA 6.2e-04
8 TCGA Stomach Adenocarcinoma 0.0510 0.0340 5.9e-03 0.017 0.027 0.007 NA 0.022 2.1e-02 4.6e-03 9.6e-02 NA 8.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 3.0 1.5 -0.8 0.0 1.7 0.1 0.9 0.9 1.1
Bipolar Disorder or Schizophrenia 0.1 0.2 0.3 0.6 -0.1 -0.3 0.5 0.5 -0.3 0.6 -0.2
Depressed Affect (Nagel 2018) 0.5 1.1 4.8 -0.1 -2.2 0.9 0.8 1.1 -1.0 0.9 -0.1
Depression (Nagel 2018) 0.8 1.2 3.9 0.0 -1.3 1.3 -0.3 0.6 -2.0 1.4 -0.2
Intelligence (Savage-Jansen 2018) 0.8 2.4 4.6 1.2 1.9 1.7 -0.5 -2.2 0.9 1.5 1.8
Neuroticism (Nagel 2018) 0.7 1.6 5.5 -0.9 -2.0 0.6 -0.3 1.5 -2.3 0.1 -0.5
Schizophrenia (2018) 0.3 0.5 1.3 -0.5 0.5 -0.4 -0.8 0.6 -1.1 0.2 -1.1
Schizophrenia vs Biploar Disorder 0.2 0.3 0.6 -0.5 -0.7 0.2 -0.6 -0.8 0.2 -0.3 -0.5
Worry (Nagel 2018) 0.5 1.1 5.6 -0.3 0.0 -0.5 -1.0 0.0 -2.4 -0.3 -1.3
Alzheimer’s Disease (in mother) 0.4 0.5 1.0 0.9 1.0 0.9 0.2 -0.8 -0.1 0.7 0.3
Alzheimer’s Disease (in father) 0.2 0.3 0.9 -0.0 0.9 -0.4 -0.2 0.4 0.6 -0.7 -0.1
Alzheimer’s Disease (including proxy) 0.2 0.3 1.1 0.7 1.0 0.8 0.1 -0.2 0.1 0.5 0.1
Crohns Disease (2017) 0.2 0.3 0.9 -0.5 -0.1 0.4 -0.8 -0.6 0.7 0.1 1.0
Irritable Bowel Disease (IBD) 0.1 0.3 0.4 -0.1 0.3 0.6 -0.4 -0.6 -0.6 0.6 0.6
Ulcerative Colitis (UC) 0.2 0.5 2.6 0.1 0.4 -0.4 0.5 -0.6 -1.6 0.1 -0.4
Major Depression (MDD) 0.5 0.6 1.0 0.5 -1.0 0.7 0.5 1.0 0.2 0.8 0.9
Reaction Time 1.1 2.0 5.7 2.0 2.1 -0.4 0.4 -2.4 0.7 1.0 -0.1
Verbal and Numeric Reasoning (VNR) 0.1 0.3 0.8 0.2 0.9 0.4 -0.5 -0.9 -0.4 0.3 0.1
Breast Cancer 0.9 2.2 8.8 -1.1 1.1 0.2 -1.6 -0.8 -3.0 0.4 -1.7
Ovarian Cancer 1.5 2.0 3.7 1.4 0.4 1.9 1.7 -1.3 0.9 1.9 1.1
Prostate Cancer 1.4 2.0 4.3 1.3 -0.3 1.9 0.2 -1.4 -0.0 2.0 2.1
Age at First Birth 1.1 1.6 3.1 -1.4 1.0 -0.9 -1.3 -0.3 -1.2 -1.7 -1.8
Bipolar Disorder (2011) 0.6 0.6 1.4 -0.7 -0.7 -1.2 -0.2 1.0 -0.5 -0.8 -0.7
Body Mass Index (BMI) (2010) 0.4 0.6 1.3 -1.1 -0.5 -0.1 -0.9 0.9 -0.5 -0.7 -0.9
Coronary Artery Disease (CAD) 0.7 0.9 2.8 -0.2 -0.7 1.7 -0.7 1.2 0.5 0.3 1.2
Crohns Disease (2012) 0.9 1.4 7.8 -1.4 0.5 0.1 -2.8 0.1 -0.5 -0.6 -0.6
Mean Putamen Volume 0.4 0.5 2.0 0.1 -0.2 1.4 -0.2 -0.1 0.1 1.2 0.6
Fasting Glucose 0.7 0.8 2.1 1.0 -0.7 0.9 1.4 0.4 0.5 0.8 1.1
HbA1C 1.3 1.5 4.4 -1.2 1.7 -0.5 -2.1 1.0 -0.2 0.0 -1.3
HDL Cholesterol 0.7 1.2 2.7 1.5 1.6 0.3 -0.2 -1.1 0.7 1.0 1.1
LDL Cholesterol 0.3 0.5 1.1 0.2 -1.0 0.9 -0.0 -0.5 0.2 0.9 0.9
Lupus 0.1 0.2 0.8 0.2 -0.3 -0.4 0.5 -0.2 0.9 -0.2 0.2
Neuroticism (2016) 0.6 0.9 3.3 -0.9 -0.4 -0.8 0.1 0.9 -0.3 -1.3 -1.8
Primary Biliary Cirrhosis 0.3 0.4 1.5 -0.7 -0.2 -0.2 -0.8 1.2 -0.1 -0.2 0.3
Rheumatoid Arthritis 0.6 0.8 2.9 0.4 -0.6 -1.5 1.7 -0.1 -0.6 -0.6 -0.5
Schizophrenia (2014) 0.2 0.3 0.6 -0.7 -0.4 -0.4 -0.6 0.6 -0.8 -0.1 -0.7
Triglycerides 1.1 1.9 7.7 -0.9 -2.8 -0.4 1.4 1.9 -0.1 -0.8 -0.3
Type 2 Diabetes (T2D) (2012) 0.8 1.0 2.6 -0.7 0.1 -1.6 0.1 1.6 -0.1 -1.3 -0.6
Ulcerative Colitis 0.3 0.4 2.2 0.8 1.5 0.4 -0.4 -0.6 0.1 0.2 0.1
Blood Eosinophil Count 0.1 0.7 3.2 -0.3 -1.8 -0.8 1.0 0.5 -0.8 -0.6 0.2
Blood Platelet Count 0.1 1.3 3.9 0.2 0.2 -1.6 1.6 2.0 -0.1 -0.9 -0.3
Blood Red Count 0.7 6.6 16.9 0.6 -3.6 1.7 2.6 0.4 4.1 0.8 3.5
Blood White Count 8.0 59.1 91.8 9.6 2.5 6.2 7.5 -7.0 8.7 9.0 8.5
Heel T-Score 0.3 2.3 7.0 -1.4 -0.0 -2.2 0.1 0.7 -1.4 -1.5 -2.6
BMI 0.9 5.0 16.5 2.2 -1.6 -0.5 4.1 0.9 3.2 0.3 2.1
Height 0.2 4.5 14.2 0.2 -2.2 3.8 0.8 -0.7 -0.1 3.3 2.2
Waist Hip Ratio (WHR) 1.5 6.9 10.8 -2.5 1.3 -2.7 -3.1 1.9 -3.0 -2.6 -3.3
Systolic Blood Pressure 0.5 2.5 8.1 1.6 2.8 0.0 -1.4 -2.0 0.5 0.9 1.6
Smoking Status 0.4 0.9 3.3 1.0 -0.9 -0.4 1.8 0.4 1.2 0.0 0.5
Allergy or Eczema 0.2 0.7 2.3 0.7 0.5 -0.6 1.5 0.2 -1.1 0.0 -0.8
Cardiovascular Disease 0.3 0.9 6.6 -0.3 0.4 -0.1 -2.6 0.1 -0.2 -0.6 0.4
Hypothyroidism (self reported) 0.9 2.2 5.9 -1.2 0.2 -2.0 -0.8 2.0 -0.8 -2.4 -1.0
Respiratory disease 0.4 0.9 5.9 0.4 0.0 0.6 0.0 -0.5 2.4 0.4 0.8
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.2 0.2 0.5 -1.5 -0.0 0.5 -0.4 -1.3 -0.5
Lung FEV1/FVC ratio 0.2 1.0 4.3 -0.7 0.5 -0.4 -1.2 2.1 -0.3 -0.7 -0.8
Lung FVC 0.2 1.1 2.3 -1.1 -1.5 1.1 -1.1 -1.4 -0.4 0.7 0.8
Neuroticism 0.6 1.5 3.1 -1.3 -1.6 0.5 -1.0 1.5 -1.8 -0.2 -1.1
Chronotype (morning person) 0.9 2.1 4.1 -1.6 -2.0 -0.9 -0.7 2.0 -0.9 -1.9 -0.6
Hair Pigment 0.1 1.5 6.6 0.1 -2.6 -0.1 1.6 0.6 1.4 -0.6 0.6
Tanning 0.1 0.7 3.8 0.3 2.0 0.5 -0.6 0.0 0.9 0.5 0.1
Hand grip strength (left) 0.3 0.8 1.7 -0.9 -1.3 1.2 -0.7 -0.7 0.4 0.5 1.0
Number of treatments/medications taken 0.1 0.1 0.4 0.3 0.3 -0.1 -0.3 0.6 0.1 0.1 -0.0
Average weekly spirits intake 0.2 0.3 1.4 0.4 -0.3 0.4 1.2 0.1 0.7 0.3 -0.1
Sensitivity / hurt feelings 0.5 0.9 3.7 -1.1 -1.2 0.2 -0.7 1.9 0.2 -0.5 -0.3
Frequency of depressed mood in last 2 weeks 0.9 1.2 2.7 -1.0 -1.7 0.5 -0.8 1.6 -1.6 0.2 -0.5
Hearing difficulty/problems: Yes 1.5 2.2 6.2 1.6 0.5 1.4 0.5 -2.5 0.4 2.4 0.8
Relative age of first facial hair 0.3 0.6 1.5 0.1 -0.1 1.0 -0.0 -1.2 -1.0 0.9 0.9
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 1.5 -0.4 -0.7 -1.2 0.6 1.1 -0.7 -1.1 -0.6
Ever used hormone-replacement therapy (HRT) 0.7 0.9 2.0 0.5 0.4 -1.0 0.6 1.4 -1.0 -1.1 -0.9
Ever had hysterectomy (womb removed) 0.3 0.4 1.4 -0.1 -0.1 -0.4 -0.6 -1.2 -0.4 -0.5 -0.9
Systolic blood pressure, automated reading 0.8 2.4 6.0 1.9 2.5 0.4 -0.2 -2.4 0.8 1.2 1.1
Eye problems/disorders: Diabetes related eye disease 1.6 1.7 3.7 1.6 -0.6 1.1 1.4 -0.2 1.9 1.4 1.4
Angina 1.8 2.3 4.7 -1.7 -0.6 -1.6 -1.6 2.0 0.8 -2.2 -0.8
Medication for hormone replacement therapy 0.2 0.2 0.6 0.5 -0.0 -0.1 0.6 0.7 -0.6 0.2 0.2
Vitamin and mineral supplements 0.4 0.5 2.2 0.1 1.5 -0.4 -0.6 -1.0 0.4 -0.7 -0.1
Supplements: Zinc 0.7 0.7 1.4 0.3 -1.2 1.1 0.6 0.2 0.8 0.9 1.1
Medication: Co-codamol 3.6 4.1 8.1 -2.8 -1.2 -1.0 -2.0 2.3 -1.7 -2.2 -2.4
Medication: Metformin 0.1 0.2 0.4 0.5 0.5 0.2 0.2 -0.2 0.5 0.5 0.7
Diabetes (father) 1.7 2.1 4.8 0.0 1.2 -2.2 -0.1 1.2 -1.1 -1.7 -2.2
Diabetes (mother) 1.2 1.5 4.2 -0.4 0.4 -2.0 -0.3 -0.2 -1.1 -1.5 -2.0
Severe depression (siblings) 0.3 0.4 1.5 -0.7 -0.2 0.1 -0.6 1.2 0.6 -0.6 -0.2
Pack years adult smoking proportion 0.7 1.0 3.7 -0.2 -1.9 -0.6 1.8 0.7 -0.7 -0.0 -0.2
Impedance of leg (right) 0.3 1.3 6.0 -0.8 1.6 -0.1 -2.5 -0.2 -0.9 -0.4 -0.6
Leg fat-free mass (left) 0.3 1.8 6.0 0.7 -1.9 0.6 2.4 0.7 1.3 0.7 1.1
Trunk fat percentage 0.4 1.7 3.5 1.8 1.2 -1.3 1.9 1.2 1.3 -0.1 0.6
Hand grip strength (right) 0.4 1.1 2.7 -1.5 -1.6 1.1 -1.4 -0.2 -0.2 0.6 0.5
Townsend deprivation index at recruitment 0.4 0.5 2.8 0.6 -0.8 0.1 1.7 0.0 0.2 0.3 0.3
Current tobacco smoking 1.9 3.2 9.9 2.8 -0.7 -0.1 3.1 -1.0 1.7 1.0 1.5
Average weekly fortified wine intake 0.6 0.7 2.0 0.6 0.4 1.0 0.4 -0.3 1.0 1.0 1.4
Maternal smoking around birth 0.2 0.2 0.6 -0.2 -0.8 0.0 0.4 0.6 0.6 0.4 0.2
Fed-up feelings 0.7 1.2 4.1 0.3 -2.0 0.9 1.4 1.2 -0.4 0.8 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.1 0.0 -1.4 0.8 0.3 0.3 0.4 0.2 0.4
Relative age voice broke 1.2 1.9 4.8 1.0 0.9 1.7 0.3 -2.2 0.9 1.7 1.4
Taking other prescription medications 0.2 0.3 0.9 0.7 1.0 -0.1 -0.5 0.4 0.6 -0.2 0.2
Age when periods started (menarche) 0.5 1.1 3.1 0.2 0.8 1.5 -0.7 -0.9 -1.2 1.8 0.6
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.2 -0.4 -0.8 -0.2 -0.5 0.0 1.0 -1.1 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.5 5.1 -0.5 -0.4 -2.3 0.3 0.5 -1.0 -2.0 -1.1
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 3.5 -1.5 -0.3 -1.3 -0.7 1.9 -0.3 -1.5 -1.0
Qualifications: CSEs or equivalent 1.5 2.0 9.0 1.4 -1.2 -1.3 3.0 1.2 -0.6 -0.5 -0.3
Serious illness, injury or assault to yourself 0.5 0.7 2.5 -0.5 -1.3 -0.5 0.4 1.6 0.2 -0.5 -0.1
High blood pressure 0.4 1.0 6.1 -0.2 0.9 -0.6 -2.5 0.0 0.0 -1.0 0.5
Hayfever, allergic rhinitis or eczema 0.5 1.1 2.7 0.7 0.8 -1.0 1.5 -0.2 -1.6 -0.3 -1.2
Multivitamins +/- minerals 1.0 1.2 2.9 0.7 -1.5 1.0 1.7 0.3 0.7 1.4 0.9
Stomach or abdominal pain in last month 0.5 0.6 1.4 -0.5 0.5 -0.4 -1.2 0.9 0.6 -1.0 -0.8
Supplements: Glucosamine 0.9 1.1 3.0 -0.5 -1.7 -1.0 0.6 0.8 -1.6 -0.6 -1.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 2.3 -0.1 -0.6 0.7 0.1 1.5 0.5 0.2 0.7
Medication: Atenolol 0.9 1.2 4.9 -1.1 1.3 -0.5 -2.2 0.2 -0.2 -0.9 -0.6
Medication: Levothyroxine sodium 0.2 0.3 0.6 -0.3 0.5 -0.6 -0.7 0.7 -0.8 -0.7 -0.2
Sitting height 0.2 1.1 5.2 -0.4 -2.3 0.7 1.5 0.1 -0.1 0.4 0.5
Chronic bronchitis/emphysema (father) 0.7 0.9 1.8 -0.7 -0.1 -1.3 -0.6 1.2 -0.6 -1.3 -0.8
High blood pressure (mother) 0.8 1.2 2.7 0.6 0.7 1.5 -1.2 -0.4 0.7 1.6 1.2
Body mass index (BMI) 0.6 2.4 8.9 1.5 -0.8 -1.1 3.0 1.6 1.9 -0.1 0.8
Impedance of leg (left) 0.3 1.4 4.3 -0.7 1.8 -0.7 -2.1 -0.4 -1.1 -0.8 -0.9
Leg predicted mass (left) 0.3 1.8 6.4 0.8 -1.9 0.6 2.5 0.7 1.2 0.8 1.0
Trunk fat mass 0.3 1.5 4.8 1.4 0.3 -1.1 2.2 1.3 1.2 -0.1 0.5
Waist circumference 0.2 0.7 2.8 0.4 -0.4 -0.9 1.1 1.7 0.7 -0.3 -0.0
Number of incorrect matches in round 1.6 2.7 8.0 2.4 1.7 0.6 0.6 -2.8 1.7 1.2 0.6
Past tobacco smoking 0.1 0.3 1.4 0.4 -0.1 -0.5 0.5 -0.1 -1.2 0.3 -0.1
Alcohol usually taken with meals 0.7 1.1 4.1 0.6 1.1 0.8 -0.7 -2.0 0.6 0.9 0.8
Nervous feelings 1.2 2.3 5.0 -1.2 0.7 -1.6 -1.5 1.0 -1.8 -1.6 -2.2
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 3.1 -1.0 -1.8 -1.0 0.1 1.0 -0.1 -0.9 -0.9
Hearing difficulty/problems with background noise 1.0 1.5 3.0 1.7 1.0 1.3 0.9 -1.3 0.8 1.7 0.7
Hair/balding pattern: Pattern 2 1.5 1.8 3.0 1.5 -0.5 1.5 0.3 -1.5 1.3 1.7 1.7
Had menopause 1.3 1.6 2.9 -0.9 -0.4 -1.4 -0.9 1.7 -1.7 -1.2 -1.4
Had other major operations 0.4 0.5 1.3 1.2 0.6 -0.2 1.1 -0.4 0.8 0.2 0.5
Forced vital capacity (FVC) 0.2 0.9 3.5 -1.5 -1.9 0.6 -0.7 -0.2 -0.7 0.3 0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.1 5.3 -1.1 -0.4 -2.3 -0.2 0.9 -1.7 -2.0 -1.6
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.8 0.1 -1.3 0.3 1.3 0.6 -0.4 0.6 0.3
Qualifications: None of the above 0.7 1.6 4.0 1.1 -0.3 1.8 -0.2 -0.8 0.7 2.0 1.7
Financial difficulties in last 2 years 1.8 2.4 9.2 -0.1 -3.0 1.1 1.6 2.2 0.7 0.5 0.6
Mouth/teeth dental problems 0.7 1.1 3.3 0.8 1.0 1.0 0.5 -1.8 1.0 0.7 1.1
Heart attack 2.8 3.6 8.5 -1.5 -0.1 -2.2 -1.5 2.0 -0.9 -2.5 -2.9
Allergy 0.4 0.9 3.1 -1.3 -1.2 0.6 -1.8 0.5 0.4 -0.4 0.4
Pain all over the body in last month 0.9 0.9 2.5 0.4 -1.6 -0.4 1.3 0.9 -1.4 0.3 0.2
Diabetes (self-reported) 0.5 0.7 2.8 1.7 1.1 -0.6 1.1 -0.3 0.2 0.1 0.2
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 2.7 1.5 -0.0 0.6 1.6 -1.0 0.1 1.1 0.8
Medication: Ramipril 1.6 2.1 5.0 0.6 0.6 2.2 -0.3 0.4 2.2 1.5 1.9
Medication: Simvastatin 0.9 1.3 2.0 -0.5 -1.4 1.3 -1.4 1.0 1.4 0.2 1.3
Fluid intelligence score 0.5 1.1 2.2 0.7 1.3 1.5 -0.4 -1.1 0.4 1.5 1.1
Illnesses of siblings 0.2 0.3 0.9 0.1 -0.7 0.3 0.5 0.2 0.6 0.6 0.9
Neuroticism score 0.6 1.2 2.1 -1.2 -1.2 -0.0 -0.7 1.4 -1.2 -0.7 -1.3
Weight 0.4 1.8 6.9 0.9 -1.4 -0.3 2.6 1.2 1.6 0.2 0.9
Impedance of arm (right) 0.8 3.8 14.8 -0.1 3.8 -0.8 -2.9 -0.7 -1.4 -1.1 -1.4
Arm fat percentage (right) 0.5 1.9 4.2 1.9 1.6 -1.5 2.0 1.2 1.2 -0.4 0.1
Trunk fat-free mass 0.4 2.1 7.6 -0.0 -2.8 1.2 2.3 0.0 1.0 1.0 0.9
Hip circumference 0.5 2.2 6.7 1.6 -0.8 -0.3 2.6 0.9 2.2 0.3 1.2
Time employed in main current job 0.4 0.4 1.2 -0.3 0.9 -0.2 -1.0 0.4 -1.1 -0.1 -0.5
Alcohol intake versus 10 years previously 1.0 1.5 3.3 -1.0 -1.1 -1.8 0.7 1.8 -0.5 -1.4 -1.0
Father’s age at death 2.5 3.4 13.9 -1.6 0.7 -1.0 -1.1 0.9 -3.7 -1.1 -2.5
Worrier / anxious feelings 0.5 0.9 3.7 0.1 0.5 -0.6 -0.7 -0.4 -1.9 -0.3 -1.4
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.1 0.3 -1.5 0.3 1.2 0.4 0.3 0.2 0.1
Falls in the last year 0.5 0.6 1.4 1.1 1.1 -1.2 0.9 -0.4 -0.0 -0.3 -0.4
Hair/balding pattern: Pattern 3 0.4 0.7 1.7 -0.9 0.2 0.1 -1.2 1.3 -1.0 -0.2 -0.2
Number of live births 1.2 1.7 6.0 2.3 -0.5 0.0 2.4 -0.7 0.0 0.9 0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 1.8 -1.3 -1.2 0.3 -1.1 0.1 -0.7 -0.0 0.2
Pulse rate 1.7 2.9 12.5 1.1 3.5 -1.4 -0.3 -2.2 -0.9 -1.0 -0.9
Happiness 2.1 2.6 3.9 1.6 -1.3 1.7 1.5 -0.9 1.7 2.0 2.0
Noisy workplace 0.4 0.5 0.9 -0.8 0.7 -0.0 -1.0 0.7 -0.9 0.1 -0.9
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.1 -0.0 0.6 -0.2 -0.5 -1.0 -1.0 0.5 -0.1
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.2 -0.0 -1.1 -0.4 1.1 0.5 0.6 -0.2 0.4
Mouth/teeth dental problems: Dentures 0.3 0.5 1.1 -0.6 -1.1 -0.2 -0.7 0.7 -1.0 -0.4 -0.3
Asthma 0.6 1.1 2.9 1.5 0.8 0.4 1.1 -1.1 1.7 0.7 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 0.7 0.2 0.8 0.1 -0.1 -0.0 0.8 0.0 -0.2
Medication: Cholesterol lowering 0.2 0.4 1.2 -0.0 0.2 -0.0 -0.7 0.5 1.1 -0.8 0.3
Depression (self-reported) 1.3 1.6 4.0 -1.6 0.0 -1.0 -1.3 2.0 -0.5 -1.3 -1.3
Medication: Lansoprazole 1.1 1.3 6.5 -1.1 0.3 0.3 -0.9 2.5 -0.0 -0.9 -0.6
Prospective memory result 0.4 0.5 1.7 1.3 0.0 -0.3 1.1 -1.0 0.5 0.4 0.1
Lung cancer (father) 1.2 1.4 3.3 1.8 1.8 -0.5 1.5 -0.8 -0.5 1.1 0.3
Illnesses of mother 0.5 0.7 2.3 0.2 -0.4 -1.3 1.5 -0.1 0.3 -0.8 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.0 3.2 -1.8 -1.2 -0.2 -1.5 0.6 -0.7 -0.6 0.1
Pulse wave Arterial Stiffness index 1.4 1.7 4.0 -1.3 0.0 -1.8 -0.2 2.0 -0.6 -1.9 -0.7
Impedance of arm (left) 0.8 3.5 15.5 0.2 3.9 -0.7 -2.9 -0.8 -1.3 -0.8 -0.9
Arm fat mass (right) 0.4 1.6 6.0 1.3 0.0 -1.1 2.5 1.4 1.3 -0.3 0.3
Trunk predicted mass 0.4 2.1 7.4 -0.0 -2.7 1.3 2.2 0.0 1.0 1.0 0.9
Standing height 0.1 1.1 3.9 -1.3 -2.0 1.4 -0.4 -0.5 -0.7 0.3 0.3
Length of working week for main job 1.2 1.4 2.6 1.4 -1.1 0.3 1.6 0.6 1.3 0.8 1.6
Exposure to tobacco smoke at home 0.5 0.6 1.7 0.3 -1.3 0.7 -0.2 -0.4 -1.0 0.6 0.8
Breastfed as a baby 1.2 1.5 3.8 0.3 1.0 1.5 -1.9 -1.9 -0.4 1.2 -0.1
Tense / ‘highly strung’ 0.4 0.6 2.8 -0.7 -1.7 -0.3 0.4 0.6 -0.3 -0.8 -0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 2.3 0.2 0.1 -0.1 0.2 1.5 0.4 -0.1 0.4
Hair/balding pattern: Pattern 4 0.3 0.8 1.1 -1.0 0.6 -1.0 -0.5 1.0 -0.8 -1.0 -1.0
Birth weight of first child 0.5 1.0 2.5 -0.9 1.0 0.1 -1.6 -0.0 -1.3 0.2 -1.3
Peak expiratory flow (PEF) 0.3 0.6 1.6 -0.8 -1.3 0.9 -1.1 0.4 0.5 0.2 0.5
Pulse wave reflection index 1.1 1.3 5.2 0.4 -2.1 -0.4 2.3 0.5 -0.3 0.2 0.6
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.6 -0.2 -0.6 0.2 0.2 0.7 -0.7 0.8 0.5
Loud music exposure frequency 0.5 0.5 1.3 0.5 0.2 -0.6 0.4 -1.2 -1.1 0.5 -0.8
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 1.6 -0.6 -0.3 -0.3 0.7 0.1 -1.3 0.3 -0.5
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 2.2 -1.0 -1.0 0.7 -1.5 0.6 1.2 -0.3 0.4
Blood clot in the leg (DVT) 1.0 1.3 3.9 1.3 1.2 1.1 0.2 -0.9 0.4 2.0 1.1
Medication: Paracetamol 0.4 0.6 2.0 0.6 0.2 -1.2 1.4 -0.1 -0.0 -0.8 -0.7
Headache pain in last month 0.1 0.2 0.7 0.4 -0.2 -0.5 0.9 0.3 -0.4 -0.6 -0.0
Medication for cholesterol, blood pressure or diabetes 0.8 1.3 5.2 0.8 -1.3 0.4 2.3 -0.9 -0.2 1.3 0.4
Glaucoma (self-reported) 1.4 1.6 3.7 1.9 0.1 1.3 1.0 -1.1 1.0 1.4 1.6
Gout (self-reported) 0.8 1.1 4.2 1.1 1.5 -0.2 -0.0 -2.1 -0.5 0.6 0.7
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 6.1 -1.6 0.1 -2.3 -1.1 1.8 -1.9 -2.5 -1.6
Medication: Amlodipine 0.2 0.3 0.8 0.5 0.3 -0.8 -0.3 -0.7 -0.2 -0.9 0.1
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.4 1.2 0.6 -0.2 1.5 -0.4 0.3 0.5 -0.1
Birth weight 0.9 2.0 5.0 -0.9 -0.4 -2.2 0.1 1.0 -2.2 -1.7 -1.1
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.4 -1.2 -0.2 -0.0 -1.2 0.9 -0.5 -0.7 -0.9
High blood pressure (siblings) 0.3 0.4 1.5 -0.4 0.8 -0.2 -1.2 0.1 0.0 -0.7 -0.6
Forced vital capacity (FVC), Best measure 0.2 0.9 3.3 -1.4 -1.8 0.3 -0.8 -0.4 -0.6 0.1 0.6
Body fat percentage 0.4 1.6 3.2 1.6 1.1 -1.5 1.8 1.6 1.2 -0.3 0.4
Leg fat percentage (right) 0.4 1.4 3.0 1.2 0.4 -1.4 1.7 1.7 1.3 -0.3 0.2
Arm fat-free mass (right) 0.5 2.4 10.8 -0.3 -3.3 0.7 2.2 1.0 1.1 0.6 0.8
Exposure to tobacco smoke outside home 0.9 1.2 3.0 1.0 -0.9 0.7 0.9 0.4 1.4 1.1 1.7
Comparative body size at age 10 0.3 1.0 4.1 -0.6 -2.0 0.4 0.5 1.6 -0.4 -0.2 0.2
Number of full brothers 0.9 1.1 2.8 1.1 -0.5 1.1 0.7 -0.8 0.7 1.7 1.2
Worry too long after embarrassment 1.2 2.1 3.0 -1.7 -0.9 -1.0 -1.7 1.5 -1.3 -1.6 -1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.5 0.4 -0.2 -1.2 1.1 0.9 0.3 -1.0 -0.1
Wheeze or whistling in the chest in last year 0.6 1.0 2.4 1.4 0.9 0.5 1.4 -0.7 0.5 1.6 0.4
Number of children fathered 0.7 0.8 2.5 -0.7 -1.6 -0.5 0.3 0.6 -1.6 -0.3 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 1.6 1.9 9.7 -0.9 0.5 -0.3 -0.8 0.9 -3.1 0.2 -1.7
Age at first live birth 0.6 1.1 3.6 0.1 1.9 -0.1 -1.1 -1.9 -0.2 0.2 -0.3
Pulse wave peak to peak time 1.4 1.6 3.8 1.0 0.0 1.9 -0.2 -1.8 0.7 1.9 0.6
Health satisfaction 1.1 1.4 4.4 2.1 0.6 0.8 1.8 -0.7 0.2 1.2 0.9
Shortness of breath walking on level ground 0.3 0.3 0.9 0.6 -0.3 -0.1 1.0 -0.9 -0.7 0.0 -0.0
Qualifications: College or University degree 0.5 1.5 7.6 -0.2 2.8 -0.7 -1.2 -1.1 -0.7 -0.5 -0.8
Eye problems/disorders: None of the above 1.8 2.1 4.3 -2.1 0.3 -1.5 -1.1 0.3 -1.9 -1.5 -1.8
Mouth/teeth dental problems: Loose teeth 2.5 3.0 6.1 1.6 0.7 1.9 0.8 -2.5 1.8 2.1 1.7
Emphysema/chronic bronchitis 0.3 0.3 1.5 0.4 -0.0 -0.7 0.0 -1.2 0.7 -0.5 0.2
Medication for pain relief, constipation, heartburn 0.3 0.5 1.2 -1.1 -0.6 -0.5 -0.8 0.4 -1.0 -0.4 -0.7
Neck or shoulder pain in last month 0.4 0.5 1.3 -0.2 -0.2 1.1 -0.8 -0.4 1.1 0.8 0.4
Medication: Blood pressure 1.0 1.7 5.9 -0.9 1.8 -0.7 -2.4 1.0 -0.1 -1.2 -0.7
Angina (self-reported) 2.0 2.6 5.4 -1.9 -0.5 -1.6 -1.8 2.1 0.7 -2.3 -0.9
Migraine (self-reported) 1.5 1.8 6.9 0.5 -0.6 1.8 0.2 -0.5 2.6 1.3 1.4
Medication: Ibuprofen 0.2 0.2 1.5 0.2 0.3 -0.2 -0.0 -0.5 1.2 -0.2 0.1
Medication: Allopurinol 1.7 2.3 10.3 0.5 3.2 -0.7 -1.1 -1.9 -1.1 -0.2 -1.0
Medication: Omeprazole 0.4 0.5 1.2 1.0 1.1 0.5 0.2 0.4 0.2 1.1 0.4
Medication: Seretide 50 evohaler 0.2 0.2 0.7 0.8 -0.2 -0.0 0.7 0.3 0.3 0.2 -0.2
Mean time to correctly identify matches 0.5 0.9 3.4 1.3 1.0 -0.8 0.4 -1.8 0.6 0.1 -0.4
Heart disease (mother) 1.0 1.2 3.0 -1.7 -0.1 -0.2 -1.5 1.7 0.1 -0.8 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 3.0 -0.2 0.9 1.3 -1.7 -0.5 1.1 0.4 0.6
Whole body fat mass 0.3 1.4 5.0 1.2 0.1 -1.1 2.2 1.5 1.1 -0.1 0.4
Leg fat mass (right) 0.4 1.5 5.2 1.1 -0.3 -0.9 2.3 1.7 1.4 -0.1 0.3
Arm predicted mass (right) 0.5 2.6 11.3 -0.3 -3.4 0.7 2.2 1.3 1.0 0.6 0.9
Pulse rate, automated reading 0.6 1.9 7.4 0.9 2.7 -1.9 0.0 -0.6 -0.8 -1.5 -0.8
Alcohol intake frequency. 1.4 3.2 8.4 0.7 -2.0 -2.8 2.9 1.0 -0.9 -1.4 -1.2
Comparative height size at age 10 0.1 0.5 2.4 -0.2 -1.5 -0.0 0.7 -0.1 -0.5 -0.4 -0.5
Number of full sisters 1.6 2.0 4.0 1.4 -1.2 0.5 2.0 -1.9 1.0 1.2 1.3
Suffer from ‘nerves’ 1.6 2.6 5.2 -1.5 0.0 -1.2 -1.7 1.5 -2.0 -1.6 -2.3
Overall health rating 0.3 0.5 1.4 0.2 -0.9 0.3 0.7 1.2 -1.0 0.5 -0.5
Chest pain or discomfort 0.4 0.5 2.5 -0.8 -0.9 0.1 -0.0 1.6 0.1 -0.2 0.3
Had major operations 1.6 1.8 5.5 -0.5 0.9 -2.3 0.3 0.0 -1.0 -2.1 -1.7
Age at last live birth 0.2 0.2 0.8 0.4 0.4 -0.2 0.0 -0.9 -0.8 0.3 -0.1
Family relationship satisfaction 2.3 2.8 7.0 -1.5 -0.7 -1.5 -0.7 2.0 -2.7 -1.7 -1.9
Leg pain on walking 0.6 0.7 2.8 1.5 0.2 -0.2 1.7 -0.6 -0.7 0.3 0.0
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.3 -0.6 -0.3 -0.6 0.1 0.7 0.3 -0.6 -1.1
Commuting to job workplace: Car/motor vehicle 1.3 1.5 3.7 0.3 -1.9 1.4 0.7 -0.1 1.9 1.1 1.0
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 5.5 -0.0 2.4 -0.7 -1.3 -1.6 -1.4 -0.4 -1.1
Medication: Aspirin 1.3 1.7 4.2 -1.3 -2.0 1.1 -1.3 1.6 1.3 -0.4 0.7
Supplements: Vitamin C 2.1 2.5 5.4 -1.9 -1.2 0.1 -2.3 2.3 -1.6 -0.5 -1.1
Knee pain experienced in last month 0.3 0.4 1.4 1.0 -0.1 0.1 1.2 0.1 -0.6 0.8 -0.2
Hypertension (Self-reported) 0.4 1.2 7.0 -0.1 1.1 0.1 -2.7 -0.3 0.1 -0.4 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 3.0 -0.7 -0.1 -0.3 0.1 1.7 -1.6 -0.1 -0.7
Illnesses of father: Heart disease 1.6 2.2 12.8 -1.2 0.6 0.9 -3.6 0.7 -1.0 0.5 -0.6
Illnesses of siblings: Diabetes 1.7 2.1 5.4 -0.9 0.6 -2.3 -0.5 0.6 -1.2 -2.0 -2.0
Smoking status: Previous 0.8 1.2 3.9 -1.7 0.2 0.9 -2.0 0.8 0.7 -0.3 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 2.8 0.3 -0.3 1.3 0.5 -0.5 0.1 1.2 1.7
Whole body fat-free mass 0.4 2.1 6.9 0.2 -2.6 0.9 2.5 0.5 1.1 0.8 0.9
Leg fat-free mass (right) 0.3 1.8 7.2 0.7 -2.0 0.3 2.7 0.6 0.9 0.6 0.8
Arm fat percentage (left) 0.6 2.2 5.0 2.1 1.6 -1.6 2.2 1.2 1.4 -0.3 0.4
Average weekly red wine intake 1.0 1.5 7.7 -1.3 1.0 0.3 -2.8 -0.1 1.0 -0.6 0.0
Handedness (chirality/laterality): Left-handed 1.1 1.3 2.4 -0.9 -1.4 -1.0 0.8 1.5 -1.2 -1.1 -1.2
Mood swings 0.4 0.6 1.6 -1.0 -1.3 1.2 -0.7 0.6 0.0 0.3 0.2
Loneliness, isolation 1.1 1.5 5.8 -0.9 -1.7 -0.2 -0.3 2.4 -0.5 -0.8 -1.1
Long-standing illness, disability or infirmity 0.6 0.9 1.9 -0.9 -0.0 -1.1 -0.5 1.3 -0.4 -1.4 -1.1
Ever had bowel cancer screening 1.4 1.7 4.9 -2.2 -0.2 -0.0 -1.9 1.4 -0.8 -0.4 -1.4
Diabetes diagnosed by doctor 0.5 0.7 2.6 1.6 1.0 -0.7 1.1 -0.6 0.2 -0.0 0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 3.3 0.9 -0.4 0.8 0.3 -1.6 1.8 1.0 0.7
Friendships satisfaction 0.4 0.5 2.5 0.8 0.2 -0.1 0.2 0.8 -1.6 0.2 0.1
Qualifications: nursing, teaching 0.3 0.4 2.3 -0.7 0.4 -0.0 -1.5 0.3 -0.6 0.1 0.3
Commuting to job workplace: Walk 0.6 0.6 2.3 -0.5 -0.1 -0.9 -0.6 0.7 -1.5 -0.6 -0.6
Eye problems/disorders: Cataract 0.1 0.1 0.3 0.3 0.1 0.2 0.4 0.5 -0.5 0.2 -0.5
Mouth/teeth dental problems: Mouth ulcers 3.8 6.1 13.5 -1.7 -0.6 -2.9 0.3 3.2 -3.7 -2.1 -2.9
Medication for cholesterol 0.2 0.2 0.7 -0.9 -0.6 -0.1 0.3 -0.0 -0.4 -0.3 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.1 4.4 -0.7 -2.1 1.1 0.1 1.5 0.4 0.2 0.6
Back pain experienced in last month 0.6 0.9 3.6 0.4 -1.3 -0.0 1.0 0.8 1.9 0.0 0.2
Mineral and other dietary supplements 0.4 0.5 2.1 -0.0 1.4 -0.3 -0.9 -0.3 0.9 -0.6 0.2
Breast cancer (self-reported) 0.4 0.5 2.5 -0.5 -1.6 -0.7 0.9 0.1 -0.4 0.0 0.0
Asthma (self-reported) 0.4 0.8 2.3 1.2 0.8 0.3 1.0 -0.9 1.5 0.6 0.2
Osteoporosis (self-reported) 1.4 1.8 8.0 0.0 2.8 0.4 -2.2 -0.4 -0.3 0.2 -0.9
Osteoarthritis (self-reported) 1.3 1.7 2.9 -0.9 -0.9 -1.7 -0.6 1.6 -0.9 -1.6 -1.6
Medication: Aspirin 0.8 1.0 2.2 -0.9 -1.5 0.9 -0.9 1.1 1.3 -0.3 0.6
Medication: Gliclazide 0.6 0.6 1.9 0.0 -0.7 1.4 0.4 -0.2 0.5 0.9 1.2
Illnesses of father: None of the above (group 1) 0.9 1.1 6.8 1.0 -0.4 -0.8 2.6 -0.7 0.2 0.1 0.1
Smoking status: Current 2.3 3.6 12.7 3.1 -0.5 -0.3 3.6 -1.2 1.4 1.0 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.3 1.3 -0.7 0.6 -0.4 -1.2 -0.0 -0.6 -0.3 0.1
Whole body water mass 0.4 2.3 7.3 0.2 -2.7 1.0 2.5 0.5 1.2 1.0 1.0
Leg predicted mass (right) 0.3 1.8 7.3 0.7 -2.0 0.4 2.7 0.5 1.0 0.7 0.9
Arm fat mass (left) 0.5 1.9 6.8 1.8 0.4 -1.1 2.6 1.1 1.7 -0.1 0.5
Number of self-reported non-cancer illnesses 0.3 0.5 2.2 -0.3 0.6 -0.3 -0.8 1.5 -0.1 -0.6 -0.6
Average weekly champagne plus white wine intake 0.4 0.5 1.4 0.5 0.4 -1.1 0.8 -1.2 -0.5 -0.1 -0.4
Miserableness 0.4 0.7 2.8 -0.2 -1.2 0.2 0.5 1.7 -0.5 0.2 -0.4
Guilty feelings 0.4 0.6 1.9 -0.9 -0.7 1.4 -1.0 0.1 -0.5 0.3 -0.6
Wears glasses or contact lenses 0.9 1.0 4.2 -1.3 -2.0 -0.0 -0.7 1.1 -0.8 0.1 0.4
Ever taken oral contraceptive pill 0.1 0.2 0.7 0.2 0.0 0.6 -0.0 -0.2 0.3 0.1 0.8
Hearing aid user 0.5 0.5 1.4 -0.0 1.1 0.6 -1.2 -0.1 1.1 0.2 -0.2
Mother’s age at death 0.2 0.3 0.9 0.0 1.0 -0.7 0.3 0.7 0.2 -0.3 -0.1
Financial situation satisfaction 3.2 4.0 9.8 2.0 -3.1 0.9 2.6 -0.2 1.8 1.2 2.4
Tinnitus: Yes, now most or all of the time 1.9 2.3 7.1 2.7 2.2 -0.4 1.4 -1.7 0.6 1.0 0.3
Commuting to job workplace: Public transport 2.0 2.3 4.8 -1.2 1.4 -1.1 -1.8 0.0 -2.2 -1.9 -1.6
Eye problems/disorders: Glaucoma 2.7 3.2 7.4 2.7 -0.3 1.2 1.9 -1.7 1.5 1.8 2.2
Medication: Blood pressure 0.4 0.7 2.3 0.3 1.2 -0.0 -1.5 -0.7 1.0 -0.2 0.6
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.9 -0.3 -1.0 -0.5 -0.2 0.2 -0.4 -0.6 -0.8
Supplements: Fish oil (including cod liver oil) 0.6 0.8 3.6 -0.6 -1.9 1.0 -0.1 0.6 -0.6 0.8 -0.3
High cholesterol (Self-reported) 0.7 1.2 3.0 -1.4 -1.6 -0.1 -0.7 1.7 -0.8 -0.8 -0.6
Medication: Bendroflumethiazide 1.0 1.6 5.1 0.8 1.8 0.5 -1.1 -2.3 1.1 0.3 0.9
Medication: Paracetamol 0.4 0.6 1.8 0.4 0.2 -1.3 1.1 -0.0 -0.5 -0.5 -1.0
Medication: Lisinopril 0.8 1.0 3.3 1.8 1.4 -1.2 0.9 -0.7 0.0 0.1 0.1
Medication: Atorvastatin 0.7 0.8 2.6 0.3 0.4 -1.4 0.8 -0.2 -0.6 -1.0 -1.6
Illnesses of father: High blood pressure 0.3 0.4 0.8 0.2 -0.5 0.8 -0.5 -0.2 0.9 0.8 0.4
Alcohol drinker status: Never 0.2 0.3 0.6 0.2 -0.8 -0.8 0.5 -0.6 -0.0 -0.5 -0.3
Ever smoked 0.2 0.4 1.5 0.3 -0.4 0.3 0.5 -0.8 1.2 -0.2 0.5
Basal metabolic rate 0.4 2.1 6.9 0.5 -2.3 0.6 2.6 0.5 1.3 0.7 1.0
Leg fat percentage (left) 0.5 1.7 3.9 1.3 0.4 -1.6 2.0 1.5 1.5 -0.4 0.3
Arm fat-free mass (left) 0.4 2.0 8.0 -0.2 -2.8 0.4 2.3 1.2 1.0 0.4 0.5
Number of operations (self-reported) 0.3 0.5 1.5 -0.0 -0.1 -1.2 0.5 0.6 -0.1 -1.2 -0.7
Average weekly beer plus cider intake 3.4 4.9 8.7 -2.1 -1.4 -2.6 0.0 2.4 -2.6 -2.2 -2.9
Irritability 1.5 2.5 8.3 -2.6 -2.9 -0.1 -0.8 1.6 -0.5 -1.0 -0.6
Risk taking 1.1 1.5 4.9 0.3 -1.9 0.4 0.8 -0.4 2.2 0.6 1.5
Ever had prostate specific antigen (PSA) test 0.9 1.1 3.3 0.3 -1.3 0.4 0.3 0.0 1.8 0.4 1.8
Fractured/broken bones in last 5 years 0.2 0.3 0.8 0.7 0.6 0.5 0.3 -0.3 -0.1 0.9 0.4
Age started oral contraceptive pill 1.3 1.6 6.8 -1.1 0.5 1.1 -2.6 1.2 -1.3 0.1 -0.7
Diastolic blood pressure, automated reading 0.8 2.4 6.3 2.5 2.5 -0.9 1.6 -0.9 1.2 0.5 0.8
Ever depressed for a whole week 1.1 1.3 2.6 1.2 -0.8 1.6 1.4 -0.2 0.5 1.6 1.2
Unable to work because of sickness or disability 1.8 2.3 8.0 -1.2 -2.4 -0.5 0.1 2.8 -0.9 -1.2 -0.9
Commuting to job workplace: Cycle 0.7 0.8 3.4 -0.7 0.8 -0.2 -1.8 -0.7 -0.9 -0.5 -0.6
Myopia 0.1 0.2 0.6 0.1 -0.0 0.2 0.5 -0.8 0.5 0.5 -0.1
Vascular/heart problems diagnosed by doctor 0.6 1.5 7.1 0.5 -1.1 1.0 2.7 -0.5 -0.0 1.5 0.0
Cholesterol lowering medication 0.6 0.9 1.7 -1.0 -1.1 0.0 -1.1 1.0 -1.3 -0.5 -1.0
Medication: Omeprazole (e.g. Zanprol) 0.5 0.7 1.7 1.1 1.0 0.8 0.4 0.4 -0.1 1.3 0.6
Pain experienced in last month 0.5 0.9 2.0 -1.0 1.4 -0.4 -1.2 0.1 -1.3 -0.8 -0.4
Supplements: Calcium 0.3 0.3 1.6 -0.1 -0.4 0.4 -0.1 1.3 0.7 0.2 0.5
Basal cell carcinoma (self-reported) 0.6 0.7 1.4 -1.0 -0.4 -0.2 -0.6 1.2 -1.2 -0.9 -0.6
Heart attack/myocardial infarction (self-reported) 2.3 2.9 7.5 -1.2 -0.1 -1.9 -1.2 1.9 -1.1 -2.1 -2.7
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 3.7 1.2 1.2 1.1 0.0 -0.5 0.3 1.9 1.1
Heart disease (siblings) 1.5 1.8 3.5 1.4 0.7 1.8 0.3 -1.2 1.1 1.9 1.7
Alcohol drinker status: Previous 1.6 1.8 10.3 1.2 -1.2 -1.0 3.2 0.5 -0.3 0.1 -0.5
Pack years of smoking 0.8 1.1 3.7 -0.1 -1.7 -0.8 1.9 0.3 -1.2 -0.0 -0.4
Impedance of whole body 0.5 2.8 9.5 -0.3 3.1 -0.6 -2.9 -0.7 -1.4 -0.7 -0.8
Leg fat mass (left) 0.4 1.6 5.5 1.0 -0.4 -1.1 2.4 1.7 1.3 -0.2 0.3
Arm predicted mass (left) 0.4 2.2 6.8 0.2 -2.6 0.7 2.6 0.8 1.2 0.8 0.8