Hub : Genes

CDKL1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1700 0.0380 0.0e+00 0.146 0.167 0.167 0.174 0.169 2.3e-17 8.2e-20 6.9e-20 1.1e-20 3.9e-20
2 GTEx Artery Aorta 0.1440 0.0570 7.8e-03 0.026 NA 0.067 NA 0.064 1.4e-02 NA 1.5e-04 NA 2.0e-04
3 GTEx Nerve Tibial 0.0959 0.0399 3.5e-03 0.018 NA 0.014 NA 0.007 1.9e-02 NA 3.4e-02 NA 9.0e-02
4 GTEx Skin Not Sun Exposed Suprapubic 0.2100 0.0730 1.5e-03 0.026 NA 0.110 NA 0.048 1.4e-02 NA 1.2e-06 NA 1.2e-03
5 GTEx Skin Sun Exposed Lower leg 0.1170 0.0370 5.5e-05 0.055 NA 0.126 NA 0.124 2.3e-05 NA 1.3e-10 NA 2.0e-10
6 GTEx Thyroid 0.2070 0.0620 2.6e-04 0.099 NA 0.121 NA 0.074 5.2e-08 NA 1.5e-09 NA 2.7e-06
7 GTEx Whole Blood 0.1380 0.0450 8.5e-06 0.085 NA 0.077 NA 0.021 2.8e-08 NA 1.4e-07 NA 4.7e-03
8 NTR Blood 0.1055 0.0197 0.0e+00 0.134 0.115 0.137 0.131 0.136 5.8e-41 4.2e-35 7.8e-42 4.8e-40 2.0e-41
9 YFS Blood 0.2038 0.0287 0.0e+00 0.302 0.324 0.343 0.342 0.345 1.1e-100 9.3e-110 3.1e-117 6.8e-117 4.2e-118
10 TCGA Breast Invasive Carcinoma 0.0420 0.0185 4.4e-06 0.013 0.034 0.018 NA 0.015 8.0e-04 1.1e-07 1.0e-04 NA 3.0e-04
11 TCGA Head and Neck Squamous Cell Carcinoma 0.0375 0.0184 1.2e-04 0.034 0.027 0.024 NA 0.025 9.1e-05 5.0e-04 8.1e-04 NA 8.0e-04
12 TCGA Brain Lower Grade Glioma 0.1249 0.0580 9.9e-07 0.060 0.056 0.055 NA 0.056 2.1e-07 5.2e-07 7.7e-07 NA 6.1e-07
13 TCGA Pheochromocytoma and Paraganglioma 0.1170 0.0750 4.9e-03 0.062 0.035 0.055 NA 0.054 1.8e-03 1.5e-02 3.2e-03 NA 3.4e-03
14 TCGA Thyroid Carcinoma 0.0890 0.0500 4.9e-03 0.017 0.014 0.016 NA 0.009 8.3e-03 1.4e-02 8.9e-03 NA 3.9e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.6 2.5 9.5 -1.9 -1.3 -0.7 -1.7 -1.6 -3.1 -0.3 -0.1 -0.7 0.1 -0.8 -0.3 2.6 -2.4
Bipolar Disorder or Schizophrenia 1.2 2.9 13.4 -1.2 -1.4 -0.5 -1.9 -2.3 -3.7 -0.0 0.0 -0.5 0.9 -0.4 0.3 3.2 -1.7
Depressed Affect (Nagel 2018) 0.2 0.4 1.0 -0.4 0.1 1.0 0.3 0.3 -0.5 -1.0 -0.6 -0.9 0.6 -0.5 0.1 0.4 -0.7
Depression (Nagel 2018) 0.2 0.3 1.1 0.6 0.7 0.8 -0.0 0.1 -0.4 0.3 0.1 -0.0 0.9 -0.0 1.1 0.7 -0.7
Intelligence (Savage-Jansen 2018) 0.4 1.1 3.2 1.8 0.7 0.5 0.8 1.3 1.2 1.4 0.9 1.6 0.3 1.2 0.8 -0.8 0.4
Neuroticism (Nagel 2018) 0.5 1.3 3.1 -1.0 -1.4 -0.8 -1.7 -1.4 -1.8 -0.7 0.0 -1.0 -0.5 -0.8 -0.2 0.9 -1.7
Schizophrenia (2018) 0.5 1.1 4.9 -0.0 -0.7 -0.1 -1.1 -1.7 -2.2 0.2 0.2 -0.1 1.1 0.1 0.6 2.1 -0.5
Schizophrenia vs Biploar Disorder 0.7 1.0 3.5 0.9 -0.0 0.8 0.9 0.3 -0.2 0.6 0.6 1.2 1.9 1.4 1.3 0.9 1.1
Worry (Nagel 2018) 0.5 1.0 3.2 -0.4 -0.6 -1.0 -1.5 -1.2 -1.8 -0.5 0.5 -0.3 0.1 -0.2 0.4 1.2 -1.7
Alzheimer’s Disease (in mother) 1.8 2.1 7.9 -0.8 1.0 2.1 1.7 0.9 0.8 -2.1 -2.8 -2.2 0.1 -1.1 -0.5 -0.5 -0.3
Alzheimer’s Disease (in father) 1.4 1.5 4.9 -1.3 -0.1 1.0 0.9 0.1 0.9 -2.2 -2.0 -1.8 -0.4 -1.6 -1.5 -0.2 0.2
Alzheimer’s Disease (including proxy) 3.6 5.2 16.9 -2.0 1.0 3.2 2.1 1.2 0.7 -3.5 -4.1 -3.6 0.2 -2.4 -1.6 0.3 -0.2
Crohns Disease (2017) 1.1 2.5 10.4 -2.5 -1.8 -0.6 -1.0 -1.5 -0.5 -0.4 -0.7 -1.8 -2.0 -1.4 -3.2 -0.2 -0.9
Irritable Bowel Disease (IBD) 0.6 1.5 5.4 -0.9 -2.3 -1.2 -1.3 -1.5 -0.4 0.5 -0.4 -1.0 -1.5 -1.0 -2.1 -0.3 -0.3
Ulcerative Colitis (UC) 0.6 1.2 5.7 0.4 -2.4 -1.3 -1.6 -1.6 -0.6 1.5 0.3 0.1 -0.8 -0.2 -0.5 -0.0 -0.3
Major Depression (MDD) 0.7 0.9 2.0 1.3 -0.8 -1.3 -0.6 -0.6 0.7 1.0 1.1 1.2 0.5 1.1 0.2 -1.4 0.5
Reaction Time 0.3 0.5 1.4 -0.8 0.1 0.2 -0.4 -0.7 -1.2 -0.6 -0.7 -0.9 -0.2 -0.7 -0.3 1.0 -1.0
Verbal and Numeric Reasoning (VNR) 0.1 0.3 1.1 0.7 -0.6 -0.5 -0.5 -0.2 -0.1 0.8 0.9 1.1 -0.0 0.8 0.4 0.1 -0.2
Breast Cancer 0.5 1.3 4.7 -0.3 -2.0 -2.2 -1.0 -1.1 0.7 0.7 0.4 0.2 -1.7 0.0 -0.7 -1.6 -0.5
Ovarian Cancer 0.4 0.5 2.7 0.3 -1.3 -0.1 -0.3 -0.1 0.7 1.6 0.5 0.5 -0.9 0.0 -0.7 -0.4 -0.3
Prostate Cancer 0.6 0.8 2.0 -0.1 -0.1 -1.2 -1.1 -1.4 0.5 1.1 0.4 -0.1 -1.4 -0.1 -1.2 -1.2 0.5
Age at First Birth 0.6 0.9 4.3 -0.8 0.1 0.1 -0.6 0.1 -1.8 0.3 0.8 0.4 0.2 -0.2 0.0 2.1 -1.8
Bipolar Disorder (2011) 0.7 0.7 3.8 0.3 0.5 0.1 -0.5 -0.3 -1.5 -0.2 -0.2 -0.1 1.0 -0.4 0.9 2.0 -0.6
Body Mass Index (BMI) (2010) 0.3 0.5 1.8 0.7 1.3 1.4 0.7 0.5 -0.4 -0.1 -0.2 -0.1 0.4 0.2 0.1 1.0 0.4
Coronary Artery Disease (CAD) 1.8 2.1 5.7 0.5 2.4 2.4 1.7 1.4 1.0 -1.7 -1.4 -1.0 2.0 -0.5 -0.1 0.2 1.3
Crohns Disease (2012) 1.1 1.8 5.9 -1.8 -1.6 -1.4 -1.2 -1.2 -0.3 0.3 0.3 -0.8 -2.2 -1.1 -2.4 -0.4 -1.1
Mean Putamen Volume 1.2 1.4 4.3 -0.6 1.0 1.3 0.8 0.3 -0.8 -2.1 -1.5 -1.3 1.3 -1.3 -0.4 1.6 0.9
Fasting Glucose 1.9 2.3 5.4 -0.8 2.2 2.3 2.1 2.1 0.7 -1.8 -2.0 -1.7 0.9 -1.1 0.0 0.3 0.5
HbA1C 0.6 0.6 1.9 0.2 0.6 1.3 0.3 0.2 -0.8 -0.3 -0.9 -1.0 1.2 -0.3 -0.1 1.4 -0.8
HDL Cholesterol 0.2 0.4 1.8 0.1 0.2 0.4 1.1 0.9 0.8 -0.3 -0.3 0.1 0.4 0.2 0.1 -0.3 1.4
LDL Cholesterol 0.9 1.4 4.2 -0.8 -0.9 -0.6 -1.3 -1.6 -1.8 1.5 0.7 0.1 -0.2 -0.1 -0.4 2.1 -1.8
Lupus 1.0 1.5 5.5 1.4 -0.5 -0.6 -0.5 -0.1 0.8 2.3 1.6 1.9 0.1 1.8 1.1 -1.0 -0.7
Neuroticism (2016) 0.5 0.7 3.4 0.6 -0.6 0.2 -0.6 -0.4 -1.2 0.3 0.6 0.4 0.8 0.6 1.2 1.0 -1.8
Primary Biliary Cirrhosis 1.1 1.6 6.5 -2.6 0.1 0.0 -0.4 -0.5 -1.7 -0.9 -1.0 -1.5 -0.6 -1.5 -1.7 1.6 -1.0
Rheumatoid Arthritis 0.3 0.5 1.3 0.8 -0.8 -0.8 -0.7 -0.6 -0.7 -0.3 0.9 0.7 0.0 0.7 1.1 0.3 0.3
Schizophrenia (2014) 0.7 1.5 7.1 -0.2 -0.9 -0.4 -1.1 -1.7 -2.7 0.2 0.2 -0.0 1.6 0.0 0.7 2.5 -0.2
Triglycerides 0.2 0.3 1.4 0.5 0.1 -0.4 -0.3 -0.3 -0.2 1.2 0.7 0.4 0.1 -0.2 -0.9 0.4 0.1
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.1 -1.4 0.1 -0.8 -0.4 0.2 -0.5 -0.7 -0.5 -1.1 -0.7 -1.4 -1.2 0.1 -0.4
Ulcerative Colitis 0.7 1.1 3.1 0.7 -1.8 -1.4 -1.5 -1.3 -1.3 1.4 1.0 0.7 -0.1 0.2 0.2 0.6 0.3
Blood Eosinophil Count 0.1 0.5 3.0 1.0 0.5 -0.1 0.8 0.5 0.5 -0.6 -0.5 0.3 -0.3 0.4 0.9 -0.3 1.7
Blood Platelet Count 0.6 6.8 27.6 -0.4 4.4 2.2 0.2 -1.1 -3.6 -0.5 0.5 0.3 5.2 0.8 -0.5 5.2 -0.3
Blood Red Count 0.4 4.2 13.7 0.5 -3.7 -2.8 -1.1 -0.8 0.2 2.9 2.7 2.7 0.5 1.8 2.7 -0.6 0.8
Blood White Count 0.2 1.5 7.5 2.7 0.1 -1.0 -0.4 -0.1 1.2 1.2 0.9 1.3 -0.1 1.0 0.7 -1.7 1.5
Heel T-Score 0.2 1.4 6.4 1.3 -2.5 -1.4 -1.0 -0.8 0.2 1.0 0.5 0.6 0.8 0.6 2.1 -0.4 -0.7
BMI 0.2 1.3 4.3 -1.5 1.0 1.3 0.8 -0.1 -1.4 -0.9 -1.3 -1.3 0.7 -0.7 -0.5 2.1 -0.7
Height 0.1 2.4 12.3 0.9 1.8 1.4 2.0 3.5 1.9 -0.8 -1.6 -0.8 -0.6 -1.2 0.8 -1.0 0.1
Waist Hip Ratio (WHR) 0.2 0.8 4.9 0.9 1.0 2.2 0.5 -0.1 -0.1 -0.6 -0.7 -0.2 1.4 0.4 0.7 0.3 -0.9
Systolic Blood Pressure 0.4 2.2 12.9 -0.9 -1.7 -1.5 -1.6 -3.6 -1.8 0.5 0.7 -0.0 1.7 0.7 -0.3 1.1 -0.4
Smoking Status 0.2 0.6 1.6 -1.0 -0.1 0.4 0.1 0.4 0.3 -0.9 -1.1 -1.0 -0.8 -1.3 -0.3 -0.6 -0.7
Allergy or Eczema 0.4 0.9 4.0 -1.6 -0.0 -0.2 -0.6 -0.5 -0.5 -0.4 -0.9 -1.2 -1.1 -1.1 -0.8 0.1 -2.0
Cardiovascular Disease 1.4 4.7 17.2 -0.6 1.2 1.1 -1.1 -2.9 -4.0 -0.1 0.7 0.5 3.9 1.7 0.9 4.1 -0.9
Hypothyroidism (self reported) 0.5 1.2 3.0 1.0 -0.9 -1.2 -1.0 -1.1 -0.7 1.1 1.7 1.7 -0.4 1.5 0.4 -0.1 1.0
Respiratory disease 0.1 0.2 0.8 0.9 -0.3 0.2 -0.2 -0.3 -0.5 -0.3 0.3 0.5 0.4 0.6 0.8 0.7 0.5
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.5 -0.1 1.0 0.6 0.8 0.8 0.5 -1.0 -1.1 -0.8 0.4 -0.9 -0.9 -0.1 1.2
Lung FEV1/FVC ratio 1.4 7.3 15.6 -3.9 2.8 2.7 2.9 1.4 -0.1 -3.6 -3.7 -3.9 0.7 -2.9 -2.3 1.8 1.0
Lung FVC 1.2 6.0 16.2 0.5 -2.1 -2.3 -4.0 -3.7 -3.0 2.5 3.2 2.6 -0.5 1.5 0.3 1.6 -2.6
Neuroticism 0.6 1.3 3.6 -1.3 -0.8 -0.4 -1.4 -1.1 -1.7 -1.3 -0.7 -1.5 -0.1 -1.2 -0.3 0.9 -1.9
Chronotype (morning person) 0.4 0.8 2.8 -1.2 0.6 0.8 0.3 0.6 -0.4 -1.7 -1.1 -1.4 0.3 -1.1 0.1 1.0 -0.0
Hair Pigment 0.0 0.7 3.0 -1.5 -1.7 0.1 -0.2 -1.5 -0.1 0.3 -0.4 -1.0 0.3 -0.1 -0.9 0.4 -0.5
Tanning 0.0 0.4 1.0 -0.7 -0.6 -1.0 -0.7 -0.4 -0.9 0.2 0.3 -0.0 -1.0 -0.7 -0.8 -0.1 -0.0
Hand grip strength (left) 0.2 0.5 1.6 0.3 -0.2 1.0 1.1 1.3 0.6 -0.4 -0.5 -0.4 0.6 -0.6 0.4 0.2 0.8
Number of treatments/medications taken 1.4 2.5 5.4 0.5 -1.2 -0.5 -1.9 -2.3 -2.1 2.1 1.7 1.7 1.1 1.9 1.1 1.4 -1.4
Average weekly spirits intake 0.8 1.0 2.7 -0.0 1.1 1.3 1.6 1.3 1.4 -0.8 -1.2 -0.8 0.3 -0.7 -0.8 -0.5 1.0
Sensitivity / hurt feelings 1.8 3.1 12.1 -3.5 -1.4 -0.8 -1.6 -1.4 -2.3 -1.6 -0.7 -2.1 -1.2 -1.8 -1.5 1.8 -1.4
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.3 0.8 0.2 1.3 0.4 0.5 -0.5 1.0 0.5 0.6 1.2 0.8 1.5 1.2 0.2
Hearing difficulty/problems: Yes 0.2 0.3 1.4 0.5 -1.2 -0.4 -0.8 -0.8 -0.6 0.1 0.1 0.1 -0.3 -0.0 0.0 0.2 -0.0
Relative age of first facial hair 1.0 2.0 5.5 1.2 -0.5 -1.0 -1.3 -0.1 -1.3 2.1 2.3 2.2 -0.2 1.5 1.7 1.0 -1.0
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 4.5 1.6 2.1 2.1 1.4 1.2 0.2 -0.1 0.3 1.1 1.8 1.6 1.0 0.4 0.8
Ever used hormone-replacement therapy (HRT) 0.4 0.6 2.7 -0.7 -1.6 -1.2 -0.6 -0.4 0.2 0.5 -0.3 -0.3 -0.6 -0.6 0.0 -0.8 -1.0
Ever had hysterectomy (womb removed) 1.1 1.3 4.6 -0.6 -0.8 -0.8 -1.6 -1.3 -1.0 2.0 1.2 0.8 -0.2 0.4 -0.2 0.4 -2.1
Systolic blood pressure, automated reading 0.7 1.9 9.6 -1.6 -2.1 -2.1 -1.6 -3.1 -0.7 0.8 0.3 -0.4 -0.4 -0.1 -1.2 -0.2 -0.9
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 8.5 1.9 1.4 0.4 1.2 1.2 1.6 -0.1 -0.2 0.4 0.5 0.1 0.2 -1.0 2.9
Angina 1.4 1.8 5.0 0.9 2.2 1.8 2.0 1.6 0.6 -1.2 -0.7 0.2 1.9 0.6 1.2 0.5 1.2
Medication for hormone replacement therapy 0.2 0.2 0.6 0.0 0.1 0.3 0.4 0.6 -0.3 -0.4 -0.8 -0.6 -0.2 -0.5 -0.1 0.6 -0.6
Vitamin and mineral supplements 0.5 0.6 2.9 -0.5 -0.9 -1.7 -1.0 -0.7 0.2 0.7 0.6 0.1 -1.1 -0.5 -0.9 -0.7 0.3
Supplements: Zinc 0.9 0.9 2.7 0.6 -1.2 -0.7 -1.0 -0.4 0.6 1.6 1.3 1.3 -0.4 1.0 0.5 -0.9 -1.0
Medication: Co-codamol 0.3 0.4 1.7 -0.0 0.1 0.1 -0.6 -0.4 -0.8 0.1 0.8 0.4 -0.4 0.8 0.5 0.1 -1.3
Medication: Metformin 0.2 0.3 0.8 -0.3 0.9 0.9 0.6 -0.0 -0.3 -0.1 -0.5 -0.3 0.5 0.0 -0.3 0.7 0.8
Diabetes (father) 0.3 0.4 1.4 0.9 1.2 0.8 0.6 -0.2 0.2 0.0 0.2 0.3 1.0 0.7 -0.1 0.1 0.9
Diabetes (mother) 0.9 1.1 3.6 -0.7 1.6 0.8 1.9 1.9 0.4 -1.2 -0.9 -0.8 -0.1 -0.4 0.4 0.1 1.3
Severe depression (siblings) 0.7 0.7 2.6 0.1 1.3 1.6 0.3 0.5 -0.4 -0.1 -0.2 -0.0 1.6 0.3 1.0 1.0 -0.9
Pack years adult smoking proportion 1.0 1.5 4.6 -1.1 0.6 -0.1 0.9 0.8 0.6 -1.3 -2.0 -1.9 -1.3 -2.2 -1.1 -0.8 0.3
Impedance of leg (right) 0.1 0.5 1.9 -0.8 -1.1 -0.9 -0.4 -0.1 -0.7 -0.2 0.4 -0.3 -0.6 -0.8 -1.4 0.4 0.1
Leg fat-free mass (left) 0.1 0.5 1.5 0.1 1.0 0.9 0.4 0.4 -0.4 -0.4 -0.9 -0.3 0.4 0.3 1.2 0.7 -1.1
Trunk fat percentage 0.6 2.5 12.8 -1.2 0.5 0.7 -1.1 -1.8 -2.5 0.9 0.4 0.6 0.8 1.2 -0.3 2.3 -3.6
Hand grip strength (right) 0.3 0.9 2.7 -0.1 0.8 1.1 1.5 1.6 1.1 -0.4 -1.1 -0.9 0.2 -0.9 -0.1 -0.1 1.3
Townsend deprivation index at recruitment 1.5 2.1 4.6 0.9 -1.6 -1.5 -1.7 -2.1 -0.7 2.0 2.0 1.8 -0.1 2.2 0.6 -0.3 -0.6
Current tobacco smoking 0.1 0.1 0.2 -0.5 0.2 -0.2 -0.1 -0.2 -0.4 0.3 -0.2 -0.1 0.1 -0.4 -0.2 0.4 0.4
Average weekly fortified wine intake 2.2 2.5 6.0 2.3 1.0 1.0 -0.1 0.2 -1.2 1.3 1.8 2.0 2.0 2.0 2.5 1.9 -0.2
Maternal smoking around birth 1.4 2.0 6.2 -0.3 1.7 0.8 2.1 2.5 1.9 -1.7 -1.4 -1.1 0.3 -1.1 -0.6 -1.2 1.4
Fed-up feelings 0.1 0.2 0.6 -0.3 -0.2 0.5 0.2 0.3 -0.3 -0.3 -0.5 -0.7 -0.2 -0.8 -0.4 0.6 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.4 3.3 1.8 -0.2 -0.5 -1.2 -1.1 -0.7 1.5 1.4 1.6 1.1 1.4 1.4 0.5 -0.9
Relative age voice broke 1.1 1.7 5.8 0.7 -2.4 -1.6 -1.5 -0.5 -1.4 0.9 1.9 1.3 -0.9 0.4 1.3 1.1 -0.9
Taking other prescription medications 1.0 1.5 3.6 0.2 -1.2 -0.8 -1.4 -1.6 -1.1 1.9 1.9 1.6 -0.2 1.7 0.6 0.6 -0.0
Age when periods started (menarche) 0.3 0.7 3.1 1.8 -0.1 -0.6 -0.3 0.2 0.5 0.9 0.9 1.1 -0.1 0.5 1.1 -0.9 0.8
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.6 -0.8 -0.2 -1.3 -0.6 0.0 -0.2 0.3 0.3 0.1 -0.8 -0.8 -0.6 -0.3 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 3.1 0.2 -0.9 -1.7 -0.1 0.5 1.4 0.2 0.7 0.1 -1.0 -0.2 0.1 -1.8 1.0
Tinnitus: Yes, but not now, but have in the past 0.1 0.2 0.6 -0.5 0.5 -0.1 -0.4 -0.2 -0.5 -0.8 -0.2 -0.2 0.3 -0.5 -0.1 0.1 0.5
Qualifications: CSEs or equivalent 1.5 2.0 4.8 -1.8 -0.1 -1.8 0.1 0.6 1.5 -0.9 -0.8 -1.6 -1.6 -1.8 -2.2 -1.8 0.9
Serious illness, injury or assault to yourself 0.3 0.4 1.0 -0.5 1.0 0.0 0.1 0.0 -0.8 -0.4 -0.7 -0.7 0.7 -0.4 -0.4 0.8 0.8
High blood pressure 1.5 4.2 14.0 -0.3 0.0 -1.1 -2.3 -3.7 -3.7 0.6 1.4 0.9 2.6 1.7 0.6 3.0 -1.4
Hayfever, allergic rhinitis or eczema 0.4 0.9 3.6 -1.1 0.3 0.3 -0.7 -0.9 -1.6 -0.7 -0.4 -0.7 0.3 -0.4 0.3 1.4 -1.9
Multivitamins +/- minerals 0.4 0.5 1.2 -0.3 0.5 1.1 0.4 0.5 -0.9 -1.1 -0.8 -0.7 -0.0 -0.2 0.6 1.1 -0.1
Stomach or abdominal pain in last month 0.7 0.8 3.5 -1.8 -0.2 -0.6 -0.3 -0.4 -1.7 0.4 0.4 0.1 0.6 -0.4 0.1 1.9 -0.4
Supplements: Glucosamine 0.5 0.6 1.4 -0.5 0.6 0.4 0.3 0.4 0.7 -1.0 -1.1 -1.2 -0.8 -1.1 -0.8 -0.8 0.2
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.8 -0.9 -0.2 -0.3 0.2 0.2 0.3 0.3 0.2 0.1 -0.5 -0.2 -0.3 -0.4 -0.1
Medication: Atenolol 1.1 1.4 6.9 1.2 1.4 1.1 1.3 0.9 0.6 -0.7 -0.4 0.2 2.6 0.8 1.6 0.4 1.1
Medication: Levothyroxine sodium 0.4 0.6 2.0 0.3 -0.2 -0.4 -0.5 -0.6 -0.7 0.9 1.4 1.4 0.4 1.2 0.5 0.5 0.6
Sitting height 0.5 3.5 9.2 -0.2 0.1 0.5 2.1 3.0 2.7 -1.9 -2.3 -2.1 -1.5 -2.0 -0.5 -2.4 1.4
Chronic bronchitis/emphysema (father) 2.1 2.4 6.4 -0.6 -0.2 -0.7 1.2 1.8 2.4 -1.1 -1.5 -1.5 -2.4 -2.0 -1.0 -2.5 0.1
High blood pressure (mother) 2.5 3.5 8.3 0.8 -1.3 -2.2 -2.8 -2.9 -1.7 2.3 2.5 2.1 0.0 1.8 0.3 0.4 -1.7
Body mass index (BMI) 0.2 0.8 2.9 -1.7 0.6 0.9 0.2 -0.8 -0.8 -0.2 -1.1 -0.8 0.2 0.0 -0.4 1.0 -1.7
Impedance of leg (left) 0.1 0.5 1.7 -0.4 -1.3 -0.8 -0.8 -0.5 -0.7 0.5 0.8 0.1 -0.7 -0.3 -1.3 0.4 -0.6
Leg predicted mass (left) 0.1 0.5 1.5 0.1 1.0 0.8 0.4 0.4 -0.4 -0.4 -0.9 -0.3 0.4 0.2 1.2 0.7 -1.1
Trunk fat mass 0.4 1.6 10.0 -1.3 0.6 0.9 -0.5 -1.1 -1.9 0.4 -0.2 0.1 0.5 0.8 -0.2 1.8 -3.2
Waist circumference 0.3 1.2 5.5 -1.0 1.1 1.7 0.2 -0.9 -1.2 0.3 -0.5 -0.1 0.7 0.9 0.0 1.4 -2.3
Number of incorrect matches in round 0.4 0.6 1.5 -0.4 -0.2 0.1 0.8 0.7 0.7 -0.9 -1.1 -1.2 -0.7 -1.2 -0.8 -0.4 -0.1
Past tobacco smoking 0.5 0.9 2.9 0.3 1.5 0.5 1.4 1.2 0.9 -0.5 -0.5 -0.4 1.2 -0.3 -0.6 -0.0 1.7
Alcohol usually taken with meals 0.8 1.4 4.3 -0.5 -1.6 -1.8 -1.2 -1.1 0.7 -0.1 0.4 -0.1 -1.6 -0.5 -1.2 -2.1 0.9
Nervous feelings 0.1 0.2 1.3 0.0 0.1 0.3 -0.2 -0.1 -0.7 -0.6 0.2 -0.1 0.3 0.0 0.0 1.1 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 1.5 0.7 0.5 0.2 -0.1 0.1 -0.7 1.2 0.9 1.0 1.1 0.9 0.9 1.1 -1.1
Hearing difficulty/problems with background noise 2.0 3.2 9.1 1.3 -2.7 -1.8 -3.0 -2.6 -2.2 1.4 1.9 1.6 -0.1 1.2 1.3 0.8 -0.7
Hair/balding pattern: Pattern 2 0.6 0.7 2.3 -0.0 -0.8 -0.3 -1.1 -1.1 -1.5 0.6 0.2 0.1 0.5 -0.3 -0.0 1.4 -1.4
Had menopause 0.3 0.3 1.1 -1.0 -0.9 -0.6 -0.5 -0.5 -0.4 0.4 0.3 -0.1 -0.9 -0.3 -0.7 -0.2 -0.1
Had other major operations 1.3 1.6 6.5 -0.6 -0.6 -0.0 -1.5 -2.3 -2.6 0.5 0.6 0.6 0.1 1.3 -0.0 1.7 -1.2
Forced vital capacity (FVC) 0.6 2.4 4.9 2.0 -0.5 -0.4 -2.1 -1.7 -2.2 1.5 1.8 1.8 0.6 1.4 1.7 1.7 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 4.2 -0.8 -1.6 -2.1 -0.8 -0.3 0.5 -0.0 0.6 -0.2 -1.6 -0.6 -0.3 -1.2 0.0
Ever unenthusiastic/disinterested for a whole week 1.1 1.3 6.1 -0.9 0.7 0.7 -0.1 -0.3 -1.9 -1.1 -0.4 -0.5 2.1 -0.5 0.9 2.5 -0.1
Qualifications: None of the above 1.9 4.1 10.8 -3.3 -0.6 -0.4 0.1 -0.4 0.0 -2.0 -2.3 -2.9 -3.2 -2.8 -2.5 -1.0 -1.7
Financial difficulties in last 2 years 1.2 1.6 4.7 0.4 -0.5 -0.5 -1.8 -1.9 -2.2 0.5 0.9 0.7 0.9 0.9 0.6 1.7 -2.1
Mouth/teeth dental problems 1.0 1.6 5.6 0.1 0.5 -0.2 1.7 2.2 1.9 -0.4 -0.7 -0.3 -1.0 -0.7 -0.6 -1.5 2.4
Heart attack 0.5 0.7 3.4 -1.8 -0.7 -0.8 -0.3 -0.4 -0.7 -0.8 -0.8 -1.1 -0.4 -1.0 -0.7 0.4 -0.5
Allergy 0.5 1.2 4.2 -0.3 0.2 0.2 1.5 1.5 1.6 -0.4 -0.7 -0.7 -0.5 -0.8 -1.3 -1.4 2.0
Pain all over the body in last month 0.6 0.7 3.4 0.7 1.0 1.0 0.3 0.6 -0.2 0.1 0.0 0.3 1.8 0.2 0.9 0.8 -1.1
Diabetes (self-reported) 0.6 0.9 3.1 -0.3 0.5 -0.6 1.1 1.0 1.7 -0.4 -0.7 -0.6 -0.4 -0.9 -1.1 -1.8 0.9
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 2.4 0.4 0.7 1.1 0.1 0.2 -1.2 -0.1 -0.5 -0.1 1.0 0.0 0.4 1.6 -0.4
Medication: Ramipril 4.1 5.2 13.3 -0.6 -3.4 -3.4 -3.7 -3.4 -3.0 1.9 2.3 1.2 -0.9 0.3 -1.0 1.3 -1.3
Medication: Simvastatin 1.3 1.9 5.5 2.3 0.4 1.0 -0.2 -0.6 -0.5 1.3 1.3 1.8 1.8 2.1 2.0 0.5 -0.5
Fluid intelligence score 0.2 0.5 2.0 1.4 0.6 0.8 0.5 0.7 0.2 0.6 0.1 0.7 1.1 0.6 0.8 0.3 -0.5
Illnesses of siblings 0.7 1.0 3.3 1.0 0.6 1.1 0.1 0.4 -1.1 -0.0 0.0 0.3 1.8 0.7 1.6 1.7 -0.6
Neuroticism score 0.9 2.0 5.7 -1.1 -1.6 -0.6 -2.2 -1.9 -2.4 -0.6 -0.0 -0.9 -0.2 -0.7 -0.0 1.6 -2.4
Weight 0.2 0.8 4.7 -1.0 0.8 1.0 0.3 -0.1 -0.9 -0.2 -1.1 -0.6 0.1 0.1 0.1 1.0 -2.2
Impedance of arm (right) 1.5 6.8 16.8 2.6 -0.2 -1.0 -3.0 -2.5 -3.0 3.0 4.1 3.9 1.7 3.4 1.1 1.9 -1.8
Arm fat percentage (right) 0.5 2.1 8.0 -0.8 1.0 1.1 -0.7 -1.7 -2.4 0.9 0.3 0.7 1.3 1.4 0.1 2.2 -2.8
Trunk fat-free mass 0.2 1.0 3.0 -0.1 0.4 0.7 1.4 1.6 1.1 -1.0 -1.7 -1.3 -0.8 -0.8 0.5 -0.7 -0.2
Hip circumference 0.2 1.0 4.3 -1.0 0.3 0.3 -0.6 -1.1 -1.8 0.4 -0.1 0.0 0.0 0.6 -0.3 1.6 -2.1
Time employed in main current job 0.9 1.1 3.4 -1.1 1.2 0.5 0.5 0.2 0.2 -0.4 -1.8 -1.6 -0.1 -1.7 -1.3 -0.2 -0.9
Alcohol intake versus 10 years previously 0.7 1.0 2.8 0.2 0.5 1.7 1.5 1.2 1.4 -0.2 -1.4 -0.9 -1.1 -0.2 -0.8 -1.1 -0.2
Father’s age at death 0.5 0.7 2.2 -0.1 1.3 1.1 1.4 1.5 0.2 -0.4 -0.8 -0.4 0.9 -0.5 0.7 0.7 0.2
Worrier / anxious feelings 0.8 1.5 5.1 0.5 -1.8 -2.1 -2.3 -1.5 -1.5 -0.0 0.9 0.4 -0.7 -0.0 0.5 0.3 -1.2
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 1.7 0.6 0.6 0.0 -0.9 -0.8 -1.3 1.3 1.2 1.1 1.3 1.3 0.3 1.2 -0.7
Falls in the last year 1.1 1.5 4.1 0.3 -1.9 -2.0 -1.9 -1.8 0.1 1.2 1.0 0.7 -1.0 0.4 -0.2 -0.9 -1.2
Hair/balding pattern: Pattern 3 0.3 0.4 1.3 -1.1 0.3 0.3 0.2 -0.3 0.0 -0.8 -0.4 -0.9 -1.1 -0.4 -1.1 -0.2 0.6
Number of live births 1.2 1.8 3.8 -1.6 0.7 0.7 1.4 1.2 0.5 -1.7 -2.0 -1.8 -0.1 -1.9 -1.1 0.0 1.6
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 4.7 -0.1 0.4 0.6 -1.0 -1.1 -2.1 -0.3 -0.0 -0.1 0.7 -0.2 0.5 2.2 -0.3
Pulse rate 0.1 0.2 0.7 -0.2 -0.8 -0.4 0.0 -0.7 0.0 -0.0 -0.6 -0.5 0.1 -0.1 -0.7 -0.4 0.3
Happiness 0.3 0.4 1.7 0.2 0.1 0.1 -0.5 -0.8 -1.3 -0.0 0.1 0.1 0.7 0.2 0.3 1.3 -0.2
Noisy workplace 0.1 0.1 0.5 0.3 -0.1 0.6 0.5 0.3 0.1 -0.2 -0.3 -0.3 0.3 -0.1 0.2 0.2 0.7
Qualifications: A levels/AS levels or equivalent 2.3 5.1 15.1 3.3 -0.5 -1.4 -1.7 -0.7 -0.0 3.2 3.5 3.9 1.4 2.9 2.1 -0.5 1.2
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 2.9 0.9 0.1 -0.7 -1.2 -0.5 -1.6 0.9 1.7 1.6 0.9 1.3 1.4 1.4 -1.2
Mouth/teeth dental problems: Dentures 0.5 0.9 2.6 -1.6 1.1 1.1 -0.1 -0.7 -1.5 -0.2 -0.8 -0.8 0.5 -0.3 -0.7 1.3 -1.2
Asthma 1.1 2.2 6.3 2.1 -0.4 0.3 -0.9 -1.3 -0.8 1.1 1.7 2.1 1.6 2.5 2.2 1.0 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 3.3 0.9 -1.1 -1.8 -0.4 -0.2 0.5 1.3 1.7 1.3 -0.7 0.9 0.8 -1.0 0.1
Medication: Cholesterol lowering 0.7 1.2 3.8 0.3 0.2 1.3 -0.4 -1.0 -1.6 0.1 0.4 0.2 1.8 1.1 1.3 1.9 -0.7
Depression (self-reported) 0.4 0.4 1.1 -0.9 -0.9 0.3 -0.7 -1.1 -0.7 -0.6 -0.5 -0.8 -0.1 -0.6 -0.4 0.8 0.0
Medication: Lansoprazole 2.8 3.2 6.8 2.3 1.3 1.2 0.8 1.3 -0.3 2.4 2.2 2.6 1.6 2.3 2.6 1.1 -0.9
Prospective memory result 0.2 0.2 0.7 -0.8 0.1 -0.4 -0.3 0.2 -0.8 0.5 0.7 0.4 -0.2 0.1 0.5 0.7 -0.2
Lung cancer (father) 2.4 2.9 9.4 -2.0 -1.8 -2.4 -1.8 -1.6 -0.7 -0.7 -0.6 -1.0 -3.1 -1.6 -1.9 -0.8 -1.7
Illnesses of mother 1.4 1.8 4.4 -1.5 0.0 0.6 0.6 0.8 0.7 -1.8 -1.9 -2.1 -1.3 -2.1 -1.7 -0.6 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 3.1 -0.2 0.5 0.8 -0.5 -0.3 -1.5 -0.2 -0.2 -0.3 0.4 -0.4 0.7 1.8 -0.7
Pulse wave Arterial Stiffness index 0.5 0.6 1.8 -0.9 -0.7 -1.1 -0.6 -0.9 -0.5 -1.2 -0.0 -0.5 -1.4 -0.6 -0.6 -0.4 -0.4
Impedance of arm (left) 1.4 6.3 13.5 1.9 -0.5 -1.2 -3.2 -2.7 -3.3 2.6 3.7 3.4 1.6 2.8 1.0 2.2 -2.3
Arm fat mass (right) 0.3 1.2 6.4 -1.1 0.9 0.9 -0.2 -1.0 -1.6 0.4 -0.4 -0.1 0.6 0.6 -0.1 1.6 -2.5
Trunk predicted mass 0.2 0.9 2.7 0.0 0.4 0.7 1.3 1.6 1.1 -0.8 -1.6 -1.1 -0.8 -0.7 0.6 -0.8 -0.1
Standing height 0.0 0.4 1.8 1.0 0.4 0.3 0.2 1.3 -0.1 -0.2 -0.3 0.0 -0.6 -0.2 0.9 0.1 -1.3
Length of working week for main job 1.0 1.1 3.0 -1.7 -0.6 -0.4 -0.9 -0.9 -0.8 -0.2 -1.0 -1.1 -1.0 -1.2 -1.4 0.8 -1.4
Exposure to tobacco smoke at home 3.7 4.1 8.4 -1.2 -0.4 0.2 1.6 1.1 2.9 -2.0 -2.4 -2.6 -2.1 -1.9 -2.7 -2.9 1.8
Breastfed as a baby 0.8 1.0 2.5 -0.2 -1.1 -1.6 -1.6 -1.4 -0.7 1.4 0.9 0.6 -0.8 -0.0 0.1 -0.1 -1.2
Tense / ‘highly strung’ 1.5 2.5 6.7 -2.6 -1.1 -1.2 -2.3 -2.0 -2.4 -0.1 0.3 -0.8 -0.7 -1.0 -1.2 1.7 -2.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.7 0.1 -0.6 -0.0 -1.1 -1.1 -1.6 0.2 0.9 0.6 1.1 0.9 0.6 1.4 -0.7
Hair/balding pattern: Pattern 4 2.0 4.8 15.0 -0.5 2.3 2.1 3.9 3.8 3.0 -1.8 -2.4 -1.8 0.8 -1.4 0.1 -1.0 1.8
Birth weight of first child 0.7 1.3 5.5 1.7 0.1 -0.1 -0.1 0.0 -0.4 0.4 0.9 1.2 2.3 1.4 2.3 0.3 0.8
Peak expiratory flow (PEF) 0.4 1.0 4.2 0.2 0.3 0.5 -0.7 -1.3 -1.8 0.3 0.7 0.7 1.1 0.8 0.7 2.1 0.1
Pulse wave reflection index 0.5 0.6 2.4 -1.1 -0.3 -0.6 -0.9 -0.7 -1.6 -0.8 0.5 -0.2 -0.4 -0.3 0.0 1.3 -0.8
Ever highly irritable/argumentative for 2 days 1.1 1.4 3.8 0.6 1.0 0.8 -0.2 -0.2 -1.6 1.1 1.2 1.6 1.9 1.2 0.9 2.0 -0.0
Loud music exposure frequency 0.5 0.6 1.8 1.3 -1.3 -0.4 -1.0 -1.1 -0.2 0.7 0.6 0.7 -0.1 0.6 0.4 -0.5 -0.5
Qualifications: O levels/GCSEs or equivalent 1.0 1.5 4.3 0.8 -0.1 -0.9 -1.5 -1.1 -2.1 0.8 1.4 1.3 1.7 0.9 0.9 1.9 0.6
Mouth/teeth dental problems: Bleeding gums 1.2 1.5 5.7 0.0 -1.5 -1.0 -1.9 -2.1 -1.0 0.9 1.1 0.5 0.8 0.9 0.2 0.4 -2.4
Blood clot in the leg (DVT) 0.6 0.8 2.6 0.7 0.5 -0.4 -0.7 0.1 -0.8 1.6 1.0 1.1 0.9 0.7 1.2 1.1 -0.4
Medication: Paracetamol 0.4 0.7 2.9 0.1 -0.7 -0.6 -0.7 -0.8 0.8 0.2 0.1 -0.1 -1.0 0.3 0.5 -1.7 -1.6
Headache pain in last month 0.7 1.2 5.9 1.1 0.8 0.9 0.1 0.6 -0.6 0.3 0.5 1.0 1.8 1.1 2.4 1.2 -1.0
Medication for cholesterol, blood pressure or diabetes 0.9 1.4 6.2 0.5 -0.7 -1.0 0.2 1.0 2.1 0.9 -0.0 0.4 -2.3 -0.5 -0.2 -2.5 0.4
Glaucoma (self-reported) 1.0 1.2 2.6 -0.5 -0.2 -0.9 0.4 0.4 1.6 -0.1 -1.2 -1.3 -1.6 -1.5 -1.1 -1.6 1.2
Gout (self-reported) 0.4 0.6 2.3 -1.1 -1.5 -0.9 -0.7 -1.4 -0.6 0.3 0.4 -0.1 -0.9 0.0 -0.4 0.3 0.1
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.6 -0.1 -0.9 -1.3 -1.3 -1.3 -0.7 1.0 1.6 1.3 -1.0 1.1 -0.3 -0.1 0.5
Medication: Amlodipine 0.2 0.3 1.4 -0.6 0.6 -0.4 -0.2 -1.2 -1.0 0.2 -0.3 -0.3 0.6 0.1 0.2 0.8 0.0
Medication: Ventolin 100micrograms inhaler 0.6 0.8 2.3 1.3 0.5 0.2 0.4 0.3 1.0 0.6 0.6 1.1 0.8 1.4 1.5 -0.9 0.1
Birth weight 1.5 3.3 15.3 3.2 1.0 0.5 -0.4 0.5 -0.7 1.0 1.5 2.1 2.4 1.9 3.9 1.1 -0.5
Chronic bronchitis/emphysema (mother) 0.2 0.3 0.9 -0.2 0.9 0.7 0.5 0.4 -0.0 -0.4 -0.2 -0.1 0.9 0.0 0.6 0.7 -0.1
High blood pressure (siblings) 0.4 0.6 1.6 -0.9 -0.7 -0.5 0.3 -0.4 0.5 -1.1 -0.4 -0.7 -0.6 -0.6 -1.0 -0.8 1.3
Forced vital capacity (FVC), Best measure 0.3 1.2 2.8 1.1 -0.4 -0.5 -1.7 -1.0 -1.5 1.2 1.3 1.2 -0.1 0.6 1.3 0.9 -1.1
Body fat percentage 0.5 2.1 9.5 -1.8 0.5 1.0 -0.6 -1.6 -2.4 0.4 -0.2 -0.0 0.7 0.7 -0.6 2.4 -3.1
Leg fat percentage (right) 0.4 1.5 6.9 -2.6 0.5 1.2 0.9 -0.5 -1.0 -0.7 -1.5 -1.3 0.2 -0.5 -1.2 1.4 -1.4
Arm fat-free mass (right) 0.3 1.6 5.4 -1.2 0.4 0.9 1.3 1.4 0.7 -1.4 -2.3 -2.0 -0.9 -1.5 0.1 -0.1 -0.9
Exposure to tobacco smoke outside home 0.1 0.1 0.4 0.1 -0.4 -0.1 -0.2 -0.7 -0.6 -0.2 0.1 0.2 0.5 0.5 0.1 0.5 0.1
Comparative body size at age 10 1.0 2.7 11.5 1.4 3.4 3.4 1.5 0.7 0.0 -0.5 -1.1 -0.1 2.0 1.2 1.3 1.1 -0.6
Number of full brothers 0.8 1.0 3.1 -0.3 -1.3 -1.5 -1.2 -0.9 -0.2 1.5 0.5 0.1 -1.8 -0.7 -0.8 -0.6 -0.6
Worry too long after embarrassment 1.5 2.5 7.9 -1.0 -2.6 -2.2 -2.8 -2.5 -2.3 -0.2 0.7 -0.4 -0.9 -0.5 -0.5 1.2 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.8 5.4 -2.3 -0.6 0.0 -0.6 -0.9 -0.9 -1.7 -1.6 -2.2 -0.8 -1.8 -1.7 0.5 -0.9
Wheeze or whistling in the chest in last year 1.0 1.7 4.2 1.3 -2.1 -1.6 -1.2 -1.5 0.1 1.1 1.6 1.6 -0.2 1.3 0.5 -1.0 1.5
Number of children fathered 2.4 2.7 5.5 -1.6 0.5 0.4 1.8 2.1 1.7 -2.2 -1.8 -2.0 -1.1 -2.3 -1.1 -0.8 1.7
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 2.3 -1.0 -1.2 -0.0 -1.3 -1.5 -1.1 -1.1 -0.6 -0.9 -0.9 -0.6 -0.8 0.5 -1.1
Age at first live birth 1.8 3.2 9.7 3.1 -0.6 0.0 -1.6 -1.2 -1.5 1.7 2.0 2.2 0.6 2.1 2.9 1.2 -1.5
Pulse wave peak to peak time 0.6 0.7 2.0 1.2 0.8 1.1 0.5 1.0 0.5 1.2 0.0 0.6 1.4 0.7 0.7 0.4 0.3
Health satisfaction 0.4 0.5 1.4 -0.1 -0.9 -0.1 -0.9 -1.2 -0.9 0.8 0.6 0.6 0.7 0.6 0.2 0.7 0.8
Shortness of breath walking on level ground 0.2 0.3 1.3 -0.4 -0.9 -0.2 -0.4 -0.7 0.4 1.1 0.1 0.1 -0.3 0.1 -0.4 -0.6 0.4
Qualifications: College or University degree 1.3 4.0 13.1 2.5 -1.1 -0.7 -1.6 -0.4 -0.5 3.6 3.1 3.2 0.8 2.6 2.0 0.4 -1.0
Eye problems/disorders: None of the above 0.6 0.7 3.1 -1.8 -0.8 -0.3 -0.7 -0.9 -1.3 -0.2 0.5 -0.1 -0.7 0.2 -0.5 0.9 -0.6
Mouth/teeth dental problems: Loose teeth 1.8 2.2 5.6 0.5 -0.9 -0.3 -1.9 -1.9 -2.4 0.8 1.7 1.4 0.7 1.0 1.6 2.2 -1.6
Emphysema/chronic bronchitis 0.5 0.5 2.3 0.9 -0.4 -1.5 -1.1 -0.5 -0.1 0.4 0.9 0.7 -0.8 -0.0 0.1 -0.4 -0.6
Medication for pain relief, constipation, heartburn 0.6 1.0 2.0 -0.3 1.2 1.4 1.0 1.2 0.1 -1.2 -1.3 -1.0 0.3 -1.1 -0.6 0.8 1.4
Neck or shoulder pain in last month 1.4 2.0 6.8 0.9 0.5 0.6 0.5 0.4 -1.1 0.9 1.7 1.8 1.8 1.9 2.6 2.2 0.6
Medication: Blood pressure 0.7 1.2 5.7 -0.6 0.8 0.7 0.1 -0.7 -1.9 -0.6 0.2 -0.3 2.1 0.3 -0.1 2.4 -0.1
Angina (self-reported) 1.3 1.8 5.0 0.9 2.2 1.8 1.9 1.6 0.4 -1.4 -0.6 0.1 1.9 0.6 1.2 0.6 1.1
Migraine (self-reported) 0.3 0.4 1.4 -0.3 -0.4 -0.3 0.2 0.9 0.7 -0.5 -0.7 -0.5 -1.1 -1.2 -0.3 -0.5 -0.4
Medication: Ibuprofen 0.5 0.6 1.5 0.9 -0.3 -1.2 0.3 0.4 1.0 0.8 0.9 0.8 -0.7 0.5 0.4 -1.2 0.5
Medication: Allopurinol 0.3 0.4 1.8 -0.6 -1.3 -1.0 -0.7 -0.9 -0.5 0.5 0.2 -0.3 -1.0 -0.3 -0.1 0.2 0.0
Medication: Omeprazole 0.4 0.4 1.3 -0.6 -0.9 -1.1 -0.9 -1.0 -0.6 -0.3 -0.1 -0.4 -0.7 -0.3 -0.2 -0.1 -0.6
Medication: Seretide 50 evohaler 1.1 1.3 3.8 1.2 1.2 1.3 -0.0 -0.2 -1.1 0.2 -0.1 0.3 1.9 0.9 2.0 1.6 -1.0
Mean time to correctly identify matches 0.4 0.8 2.6 -1.6 -0.3 -0.3 -0.8 -1.3 -1.1 -0.4 -0.7 -1.2 -0.7 -0.9 -0.7 0.7 -0.9
Heart disease (mother) 0.2 0.2 1.2 1.1 0.3 -0.4 0.1 0.1 0.3 0.3 -0.0 0.4 0.9 0.3 0.5 -0.4 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 3.7 -0.2 0.0 -1.5 0.2 0.3 1.5 0.3 0.0 -0.1 -1.2 -0.4 -1.3 -1.9 1.2
Whole body fat mass 0.4 1.6 8.8 -1.7 0.6 1.1 -0.2 -1.1 -1.9 -0.1 -0.8 -0.5 0.4 0.3 -0.4 1.9 -3.0
Leg fat mass (right) 0.3 1.2 4.4 -2.1 0.7 1.2 0.7 -0.4 -1.0 -0.7 -1.5 -1.2 0.3 -0.4 -0.7 1.4 -1.7
Arm predicted mass (right) 0.3 1.7 6.2 -1.4 0.4 1.0 1.3 1.2 0.5 -1.5 -2.5 -2.2 -0.8 -1.6 -0.0 0.1 -0.8
Pulse rate, automated reading 0.8 2.5 6.7 -2.0 -0.7 0.7 0.5 -0.2 0.8 -2.2 -2.3 -2.6 -1.4 -2.0 -2.2 -1.0 -0.3
Alcohol intake frequency. 0.2 0.5 2.1 -0.0 1.5 0.7 0.8 0.5 0.4 -0.3 -1.1 -0.7 1.0 -0.3 -0.2 -0.5 0.1
Comparative height size at age 10 0.3 1.6 8.0 -0.2 -0.2 -0.3 -1.3 -0.9 -1.7 1.4 1.2 1.0 0.1 1.2 0.7 1.4 -2.8
Number of full sisters 0.2 0.3 0.9 -0.3 -0.0 -0.5 -0.4 -0.0 -0.1 0.8 0.8 0.4 -0.7 0.4 -0.4 -0.4 -1.0
Suffer from ‘nerves’ 0.2 0.4 1.1 -0.5 -0.5 -0.2 -0.7 -0.9 -0.9 0.0 0.2 -0.1 0.9 0.1 0.3 1.0 -0.8
Overall health rating 0.5 1.1 5.0 0.2 -0.8 -0.9 -1.5 -2.2 -0.3 1.1 1.1 0.9 -0.2 1.2 -0.2 -0.8 -0.7
Chest pain or discomfort 1.8 2.7 6.5 1.8 0.9 0.5 -0.5 -0.7 -1.6 1.3 1.8 2.1 2.5 2.5 1.9 1.9 0.1
Had major operations 0.7 0.9 3.3 0.2 -0.0 -1.2 -0.7 -0.6 0.0 1.8 1.5 1.0 -0.9 1.2 -0.3 -0.5 -0.4
Age at last live birth 0.8 1.1 6.8 0.0 -1.5 -0.4 -1.6 -1.2 -0.5 0.3 -0.0 -0.1 -1.3 -0.4 0.1 -0.2 -2.6
Family relationship satisfaction 0.5 0.6 2.3 1.5 -0.5 -1.0 -1.1 -0.9 -0.7 0.7 0.6 0.7 0.5 0.4 0.7 0.6 -0.1
Leg pain on walking 0.5 0.6 1.8 -1.3 -1.3 -0.0 -0.6 -0.7 -1.3 -0.3 -0.3 -0.5 -1.0 -0.7 0.0 0.6 -0.3
Qualifications: NVQ or HND or HNC or equivalent 1.3 1.6 5.0 0.9 1.3 1.1 2.2 2.2 1.5 -0.7 -0.3 0.2 1.0 0.4 0.1 -0.4 2.1
Commuting to job workplace: Car/motor vehicle 3.0 3.4 11.3 -3.2 -0.7 -0.8 0.8 0.5 0.6 -2.1 -1.5 -2.3 -2.4 -2.4 -3.4 -0.7 0.2
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 1.9 -0.1 0.3 1.1 1.2 0.9 1.4 -0.3 -1.1 -0.7 -0.6 -0.7 -0.1 -1.1 1.0
Medication: Aspirin 1.1 1.4 4.7 1.3 -0.0 -0.6 -0.7 -1.1 -0.9 1.2 1.4 1.6 2.2 1.8 0.8 0.7 -0.1
Supplements: Vitamin C 1.4 1.6 3.9 1.8 1.3 2.0 1.3 1.3 0.7 -0.2 0.3 1.1 1.9 1.4 1.8 0.1 0.3
Knee pain experienced in last month 0.9 1.3 5.4 -2.3 0.5 0.7 0.5 -0.3 -0.3 -1.7 -1.5 -1.9 -0.2 -1.2 -1.4 0.1 0.2
Hypertension (Self-reported) 1.2 3.4 11.0 -0.2 0.4 -0.5 -1.7 -3.3 -3.2 0.4 1.1 0.7 2.8 1.7 0.7 2.9 -1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.8 4.0 -0.9 1.4 1.9 1.6 1.7 -0.0 -2.0 -1.5 -1.6 0.6 -1.4 -0.3 1.2 0.2
Illnesses of father: Heart disease 0.4 0.6 1.7 -0.7 0.0 0.4 1.0 1.3 0.6 -1.1 -0.5 -0.6 1.1 -0.7 -0.1 0.2 0.7
Illnesses of siblings: Diabetes 0.6 0.7 2.2 -0.7 -1.0 -0.8 -0.8 -1.4 -0.2 0.8 0.7 0.3 -1.2 0.4 -1.5 -0.4 -0.1
Smoking status: Previous 0.7 1.0 3.5 -1.1 -1.1 -0.3 -0.6 -0.2 0.1 -1.0 -1.1 -1.2 -1.9 -1.1 -0.0 -1.0 -1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 0.6 0.7 -0.1 0.3 -0.1 0.1 0.1 -0.6 -0.5 -0.4 0.3 -0.1 0.8 -0.4 -0.7
Whole body fat-free mass 0.1 0.7 2.1 0.0 0.7 0.9 1.1 1.2 0.6 -0.7 -1.5 -0.9 -0.3 -0.4 0.9 -0.1 -0.6
Leg fat-free mass (right) 0.1 0.4 2.0 0.4 0.7 0.8 0.1 0.2 -0.4 0.1 -0.6 0.0 0.3 0.5 1.3 0.5 -1.4
Arm fat percentage (left) 0.6 2.3 9.3 -1.0 0.8 0.9 -0.9 -1.9 -2.5 0.9 0.3 0.7 1.3 1.4 0.1 2.4 -3.0
Average weekly red wine intake 0.6 0.9 3.5 -1.9 -0.2 0.6 0.5 0.2 -0.3 -1.0 -0.9 -0.9 -0.3 -0.8 -1.6 0.7 1.3
Handedness (chirality/laterality): Left-handed 1.6 2.0 6.0 2.5 0.2 0.1 -1.0 -1.2 -0.8 1.4 1.6 1.8 1.8 1.9 1.9 0.7 0.1
Mood swings 0.6 1.1 4.7 -0.7 -1.7 -0.1 -1.5 -1.7 -1.1 -0.4 -0.0 -0.8 0.0 -0.3 -0.2 0.4 -2.2
Loneliness, isolation 0.3 0.5 1.8 -0.6 -0.2 -0.0 -0.8 -1.4 -1.0 -0.5 -0.1 -0.5 -0.1 0.1 0.2 0.6 -1.2
Long-standing illness, disability or infirmity 0.6 0.9 2.9 1.2 -0.2 0.5 -0.6 -1.2 0.0 1.1 1.1 1.4 0.7 1.7 0.8 -0.4 -0.1
Ever had bowel cancer screening 0.8 0.9 5.3 -2.3 -0.6 -0.6 -0.2 -0.6 0.6 -0.4 -0.2 -0.9 -1.1 -0.9 -1.2 -0.9 -0.8
Diabetes diagnosed by doctor 0.6 1.1 2.0 -0.5 1.0 0.3 1.4 1.2 1.3 -1.0 -1.3 -1.1 0.1 -1.0 -0.9 -0.9 1.3
Ever had stillbirth, spontaneous miscarriage or termination 4.4 4.7 10.2 0.2 -1.0 -1.3 -2.7 -3.2 -3.1 2.4 2.8 2.1 0.5 2.0 0.7 2.2 -2.8
Friendships satisfaction 0.2 0.2 0.8 0.5 -0.6 -0.8 -0.4 -0.0 -0.7 -0.1 0.1 -0.0 0.2 -0.3 0.0 0.9 0.1
Qualifications: nursing, teaching 1.0 1.6 4.1 1.5 0.7 0.3 -0.1 -0.0 -0.2 1.7 1.7 2.0 1.5 1.9 1.5 0.8 1.0
Commuting to job workplace: Walk 1.1 1.2 2.9 0.5 -1.1 -1.0 -1.4 -1.1 -1.7 0.0 1.2 0.9 1.3 0.4 1.1 1.6 0.8
Eye problems/disorders: Cataract 0.4 0.5 2.1 1.4 0.5 0.4 0.1 0.5 -0.1 0.4 0.3 0.6 1.5 0.4 1.1 0.5 -0.6
Mouth/teeth dental problems: Mouth ulcers 1.2 1.9 4.1 1.9 -0.7 0.2 -0.9 -0.8 -1.3 1.4 1.7 1.9 1.1 2.0 1.9 1.3 -0.4
Medication for cholesterol 0.5 0.8 2.5 -0.5 0.0 0.8 1.0 1.6 1.5 -0.5 -0.7 -0.6 -0.6 -0.8 -0.0 -0.9 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.5 5.7 0.6 1.3 1.2 2.2 2.4 2.2 -0.2 -0.4 -0.0 -0.2 0.2 0.5 -0.9 0.9
Back pain experienced in last month 0.7 1.0 3.4 -0.1 -0.7 -1.0 -0.8 -0.8 -1.3 0.7 1.8 1.3 -0.2 1.1 1.0 1.0 0.3
Mineral and other dietary supplements 0.6 0.8 1.9 1.2 0.3 0.4 0.3 0.2 -0.6 1.1 1.1 1.3 1.2 1.0 1.1 1.4 0.0
Breast cancer (self-reported) 0.3 0.4 1.2 0.9 0.3 0.5 -0.1 -0.3 0.1 0.7 0.8 0.9 0.6 1.1 0.6 -0.1 0.2
Asthma (self-reported) 0.7 1.4 4.2 1.6 -0.4 0.4 -0.6 -1.2 -0.6 0.8 1.2 1.6 1.4 2.0 1.8 0.9 0.3
Osteoporosis (self-reported) 2.0 2.4 6.8 -1.1 -1.1 -1.7 -0.1 -0.1 1.5 -0.2 -0.5 -1.0 -2.6 -1.6 -2.5 -2.3 2.1
Osteoarthritis (self-reported) 0.5 0.6 1.5 0.1 0.5 0.9 0.9 0.5 1.1 -1.0 -1.0 -0.7 -0.2 -0.6 0.0 -0.9 1.2
Medication: Aspirin 1.1 1.5 7.5 1.4 0.6 0.1 -0.1 -0.4 -0.4 1.1 1.2 1.6 2.7 1.8 1.2 0.7 0.2
Medication: Gliclazide 0.3 0.3 1.1 0.9 -0.2 0.6 0.7 0.3 0.2 -0.2 -0.1 0.3 1.1 0.6 0.5 0.4 0.6
Illnesses of father: None of the above (group 1) 0.8 1.0 4.0 -0.9 -0.9 -0.5 -1.3 -1.1 -0.7 0.7 0.1 -0.2 -2.0 -0.4 -1.2 -0.1 -1.6
Smoking status: Current 0.1 0.1 0.3 -0.5 0.1 -0.1 -0.0 -0.2 -0.3 0.6 0.1 0.2 0.1 -0.1 -0.2 0.4 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.7 -0.3 -0.5 -0.4 -1.1 -1.3 -0.6 0.8 0.6 0.3 -0.0 0.0 0.1 0.6 -0.4
Whole body water mass 0.1 0.8 2.4 0.1 0.8 1.0 1.2 1.3 0.7 -0.8 -1.6 -0.9 -0.3 -0.5 0.9 -0.3 -0.4
Leg predicted mass (right) 0.1 0.5 2.1 0.5 0.9 0.9 0.2 0.2 -0.4 0.1 -0.6 -0.0 0.4 0.5 1.4 0.6 -1.5
Arm fat mass (left) 0.3 1.3 7.3 -1.2 0.8 0.9 -0.3 -1.0 -1.7 0.4 -0.4 -0.0 0.7 0.7 0.0 1.8 -2.7
Number of self-reported non-cancer illnesses 0.2 0.3 1.0 -0.5 0.3 0.4 -0.4 -1.0 -0.7 -0.2 0.2 0.0 0.7 0.4 0.0 0.7 -0.6
Average weekly champagne plus white wine intake 1.5 2.0 8.4 2.9 1.0 0.2 1.1 1.6 0.6 -0.4 0.9 1.2 1.6 0.8 1.8 0.4 2.3
Miserableness 0.2 0.3 1.3 0.2 -0.1 0.9 -0.3 -0.1 -0.9 -0.3 -0.1 -0.1 1.2 0.2 0.4 0.7 -0.4
Guilty feelings 0.4 0.7 1.8 -0.7 -1.0 -0.8 -1.4 -1.2 -0.9 0.2 0.1 -0.4 -0.3 -0.5 -0.4 0.9 -1.2
Wears glasses or contact lenses 1.0 1.2 3.0 1.4 0.5 -0.1 0.3 0.3 0.6 0.8 1.5 1.7 1.3 1.7 1.7 -0.3 0.6
Ever taken oral contraceptive pill 0.3 0.3 1.5 0.3 -0.8 -0.6 -0.9 -1.2 -0.7 -0.8 -0.1 -0.3 -0.1 -0.1 -0.1 0.1 -0.1
Hearing aid user 0.4 0.5 2.3 0.1 -0.6 -1.5 -0.5 0.3 -0.6 -0.1 0.3 0.0 -1.2 -0.6 0.0 0.1 -1.3
Mother’s age at death 0.6 0.7 2.1 -0.3 0.1 -0.9 -1.1 -0.5 -0.5 1.4 0.8 0.6 -1.3 -0.1 -1.0 -0.3 -1.4
Financial situation satisfaction 1.4 1.7 4.5 -0.1 -1.3 -1.5 -2.0 -2.1 -1.9 1.5 0.7 0.6 -0.2 0.5 0.7 0.9 -1.9
Tinnitus: Yes, now most or all of the time 0.7 0.9 2.2 0.7 -0.6 -1.0 -1.4 -1.5 -1.2 0.9 0.9 0.9 0.1 0.9 1.0 0.4 -0.4
Commuting to job workplace: Public transport 2.0 2.4 5.5 0.9 -0.3 -0.8 -1.6 -1.4 -2.1 2.3 1.7 1.6 1.0 1.2 1.9 2.0 -1.4
Eye problems/disorders: Glaucoma 0.9 1.1 4.6 0.4 0.1 -1.1 0.6 0.9 1.7 0.3 -0.8 -0.5 -1.1 -1.0 -0.5 -1.4 2.2
Medication: Blood pressure 1.2 2.2 9.7 -0.7 -0.7 -1.7 -2.0 -3.1 -2.4 0.5 1.0 0.6 1.1 0.8 0.1 1.6 -1.4
Pain type(s) experienced in last month: Hip pain 0.8 1.1 2.8 -1.7 -1.3 -1.4 -1.1 -0.9 -0.9 0.4 0.9 0.2 -1.4 -0.3 -1.0 0.1 -1.2
Supplements: Fish oil (including cod liver oil) 0.9 1.2 3.8 -1.3 -0.0 -0.2 0.1 0.2 0.4 -1.9 -1.7 -1.8 -0.8 -1.4 -0.9 -1.1 0.1
High cholesterol (Self-reported) 0.8 1.5 5.4 0.6 1.7 1.4 0.1 -0.5 -1.5 0.3 0.7 0.9 2.3 1.3 0.9 2.0 0.3
Medication: Bendroflumethiazide 1.3 2.0 6.9 -1.2 -1.2 -0.6 -1.9 -2.6 -2.2 0.6 0.7 0.3 0.8 0.7 0.0 1.8 -2.1
Medication: Paracetamol 0.4 0.7 3.3 -0.4 -0.5 -0.6 -0.6 -0.6 0.8 -0.5 -0.5 -0.6 -1.3 -0.4 -0.2 -1.8 -1.1
Medication: Lisinopril 0.5 0.6 1.8 -1.2 0.1 0.1 -0.6 -1.1 -1.1 -0.3 -0.3 -0.4 1.1 -0.0 -0.3 1.4 0.9
Medication: Atorvastatin 2.0 2.4 8.1 -1.1 -1.2 -0.9 -2.1 -2.6 -2.8 0.9 1.4 0.7 1.1 1.1 -1.0 2.1 -0.6
Illnesses of father: High blood pressure 2.0 2.5 6.4 0.1 -0.5 -0.4 -1.8 -2.5 -2.3 1.4 1.5 1.3 2.2 1.9 1.2 1.7 -1.0
Alcohol drinker status: Never 1.4 1.6 3.0 -1.5 1.2 1.4 0.1 -0.2 -1.2 -1.6 -1.7 -1.7 1.1 -1.4 -0.3 1.1 -1.7
Ever smoked 2.1 3.8 7.6 0.6 -1.9 -1.6 -2.8 -2.4 -2.5 2.3 2.3 2.0 -0.5 1.9 1.5 1.3 -2.0
Basal metabolic rate 0.1 0.6 2.2 -0.3 0.8 1.0 1.0 0.9 0.2 -0.6 -1.5 -0.9 -0.2 -0.3 0.7 0.2 -1.0
Leg fat percentage (left) 0.4 1.4 6.2 -2.5 0.3 1.1 0.5 -0.7 -1.1 -0.2 -1.2 -1.0 0.0 -0.3 -1.2 1.4 -2.0
Arm fat-free mass (left) 0.2 1.1 4.0 -0.7 0.7 1.1 1.4 1.4 0.7 -1.1 -2.0 -1.6 -0.5 -1.0 0.3 -0.1 -0.5
Number of operations (self-reported) 0.2 0.3 0.9 -0.9 0.5 0.0 -0.5 -0.7 -0.8 -0.2 -0.1 -0.4 -0.9 -0.0 -0.7 0.3 -0.6
Average weekly beer plus cider intake 0.7 1.0 3.1 1.1 0.6 1.3 1.8 1.6 1.1 0.8 -0.1 0.4 -0.0 0.7 1.1 -0.4 1.0
Irritability 0.7 1.1 7.0 -1.1 -0.7 1.0 -0.5 -0.6 -0.9 -0.0 -0.6 -1.0 -1.2 -0.8 -0.8 0.7 -2.6
Risk taking 0.3 0.4 1.6 -0.6 -0.4 -0.2 -1.1 -1.0 -1.0 0.0 0.3 0.1 -0.5 0.2 0.3 0.6 -1.3
Ever had prostate specific antigen (PSA) test 0.3 0.4 1.8 -0.3 -0.5 -1.3 -0.6 -0.9 0.5 0.0 -0.3 -0.4 -0.7 -0.4 -0.2 -1.0 -0.1
Fractured/broken bones in last 5 years 1.1 1.4 3.1 0.7 -0.6 -0.4 -1.3 -1.8 -1.7 1.3 1.4 1.3 1.0 1.6 0.4 1.2 -0.8
Age started oral contraceptive pill 0.7 0.9 2.2 1.1 0.7 0.3 0.0 0.0 -0.4 1.5 1.0 1.3 1.2 1.2 1.0 0.8 -0.9
Diastolic blood pressure, automated reading 0.4 1.2 4.8 -1.6 -1.9 -1.0 -0.8 -2.2 -0.6 -0.6 -0.6 -1.0 -0.4 -0.3 -1.3 -0.3 -0.5
Ever depressed for a whole week 1.1 1.4 6.0 -0.4 -0.3 0.1 -1.0 -1.2 -2.3 -0.5 0.6 0.4 1.8 0.3 1.1 2.5 -0.0
Unable to work because of sickness or disability 0.5 0.6 1.7 -0.3 -0.8 -1.3 -0.7 -0.4 0.3 0.5 -0.3 -0.5 -1.3 -0.6 -0.5 -1.0 -1.2
Commuting to job workplace: Cycle 0.9 1.1 2.4 0.9 1.5 1.6 0.7 1.2 0.1 -0.1 -0.9 -0.5 1.3 -0.5 1.2 1.2 1.3
Myopia 0.9 1.3 5.9 -0.5 -0.6 -0.0 -1.2 -2.4 -1.3 1.0 0.7 0.3 0.1 0.9 -0.3 1.2 -2.4
Vascular/heart problems diagnosed by doctor 1.5 4.0 13.2 0.0 -0.3 0.7 2.1 3.6 3.5 -0.7 -1.4 -1.0 -2.7 -1.8 -0.7 -2.9 1.7
Cholesterol lowering medication 2.5 3.7 9.2 2.2 -0.3 -1.5 -1.9 -2.0 -1.6 2.6 2.8 3.0 1.1 2.6 1.0 0.4 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.4 0.4 1.2 -0.9 -0.8 -0.9 -0.5 -0.5 -0.9 -0.2 -0.2 -0.5 -0.6 -0.6 -0.3 0.5 -1.1
Pain experienced in last month 0.5 0.9 3.7 0.8 0.6 0.9 1.2 1.1 1.9 -0.2 -1.1 -0.7 -0.0 -0.3 -0.4 -1.4 0.3
Supplements: Calcium 0.5 0.5 1.7 0.9 -0.4 -0.5 -0.7 -0.6 0.2 1.3 0.6 0.7 -0.4 0.7 0.6 -0.6 -1.0
Basal cell carcinoma (self-reported) 1.8 2.1 4.6 0.8 0.2 -0.6 -1.8 -1.1 -2.0 1.7 2.2 1.9 1.0 1.6 0.7 1.8 -1.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 4.0 -2.0 -0.8 -0.9 -0.4 -0.5 -1.1 -0.6 -0.6 -1.0 -0.2 -0.9 -0.6 0.7 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 3.0 0.4 0.4 -0.4 -0.9 -0.1 -1.1 1.7 1.0 1.1 1.0 0.8 1.1 1.4 -0.5
Heart disease (siblings) 0.6 0.8 2.3 -0.4 -1.2 -1.2 -1.4 -1.5 -0.7 0.9 0.7 0.5 -0.4 0.3 -0.8 -0.3 -0.9
Alcohol drinker status: Previous 0.8 1.0 2.2 -0.4 -1.5 -1.3 -1.5 -1.4 -0.6 1.4 0.8 0.4 -0.1 0.3 0.4 -0.1 -1.4
Pack years of smoking 1.1 1.7 4.9 -1.3 0.6 0.1 1.1 0.8 0.8 -1.6 -2.2 -2.0 -1.1 -2.1 -1.0 -0.8 0.2
Impedance of whole body 0.6 3.0 7.3 1.0 -0.9 -1.0 -2.3 -1.9 -2.5 1.8 2.7 2.2 0.8 1.6 0.1 1.7 -1.7
Leg fat mass (left) 0.3 1.2 4.5 -2.1 0.5 1.1 0.5 -0.5 -1.0 -0.4 -1.3 -1.0 0.1 -0.3 -0.8 1.3 -2.1
Arm predicted mass (left) 0.3 1.4 4.9 -0.9 0.7 1.1 1.5 1.5 0.9 -1.2 -2.2 -1.7 -0.7 -1.2 0.1 -0.3 -0.4