TWAS hub - CEBPA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.109	0.0224	6.6e-12	0.024	0.044	0.041	0.045	0.034	2.3e-08	2.9e-14	2.0e-13	1.9e-14	1.9e-11
2	TCGA	Cervical Squamous Cell Carcinoma	0.141	0.0540	1.9e-03	0.003	0.075	0.062	NA	0.011	2.2e-01	1.6e-04	5.5e-04	NA	9.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Waist Hip Ratio (WHR)	39.4	177.3	306.2	7.0	17.5
Blood Red Count	14.5	140.5	231.0	-7.1	-15.2
Falls in the last year	4.3	5.8	6.5	2.6	2.2
Lung FEV1/FVC ratio	4.0	20.4	21.1	4.6	4.4
Irritability	4.0	6.8	7.6	2.4	2.7
Ever used hormone-replacement therapy (HRT)	3.9	5.0	7.1	1.7	-2.7
Medication: Co-codamol	3.8	4.4	8.1	-0.8	-2.9
Age started oral contraceptive pill	3.5	4.3	6.9	-2.6	-1.3
Nervous feelings	3.4	6.4	9.2	1.9	3.0
Financial difficulties in last 2 years	3.0	4.0	5.9	-1.5	-2.4
Chronic bronchitis/emphysema (mother)	3.0	3.5	5.3	-2.3	-1.3
Pain all over the body in last month	2.9	3.1	6.3	0.0	-2.5
Age at last live birth	2.9	4.2	5.6	-2.4	1.7
Migraine (self-reported)	2.8	3.4	6.9	2.6	0.1
Hip circumference	2.7	11.8	23.1	-0.6	-4.8
Pulse wave reflection index	2.6	3.2	5.9	-0.7	-2.4
Medication: Ventolin 100micrograms inhaler	2.6	3.3	5.8	-2.4	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.6	10.2	-1.0	-3.2
Medication: Simvastatin	2.4	3.5	4.9	-2.2	-1.4
Impedance of arm (left)	2.4	10.9	11.3	3.4	3.2
Pulse wave peak to peak time	2.3	2.7	5.5	0.2	2.3
Other serious medical condition/disability diagnosed by doctor	2.2	2.9	5.1	2.2	0.8
Supplements: Glucosamine	2.2	2.8	4.2	2.0	1.2
Osteoarthritis (self-reported)	2.2	2.8	5.3	2.3	-0.5
Neuroticism (Nagel 2018)	2.1	4.9	5.2	2.1	2.3
Neuroticism (2016)	2.1	3.0	4.0	1.4	2.0
Type 2 Diabetes (T2D) (2018)	2.0	3.7	3.9	-1.9	-2.0
Average weekly spirits intake	2.0	2.4	4.4	2.1	0.6
Medication for hormone replacement therapy	2.0	2.3	4.6	2.1	-0.0
Pulse wave Arterial Stiffness index	2.0	2.3	4.7	0.1	-2.2
Gout (self-reported)	2.0	2.8	4.8	-2.2	-0.8
Age at first live birth	1.9	3.3	3.6	-1.9	1.7
Mouth/teeth dental problems: Loose teeth	1.9	2.3	3.9	0.8	2.0
Number of full sisters	1.9	2.3	4.5	2.1	0.3
Impedance of whole body	1.9	9.6	11.8	2.7	3.4
Leg fat mass (left)	1.9	7.5	14.9	0.2	-3.9
Blood Platelet Count	1.8	21.3	42.2	-0.6	6.5
Heel T-Score	1.8	14.3	20.2	-2.9	-4.5
Smoking Status	1.8	4.3	7.8	2.8	0.9
Hypothyroidism (self reported)	1.8	4.1	7.2	2.7	1.0
Diabetes (self-reported)	1.8	2.8	3.1	-1.6	-1.8
Leg fat mass (right)	1.8	7.0	13.8	0.3	-3.7
Diabetes diagnosed by doctor	1.8	3.0	4.1	-1.4	-2.0
Breast cancer (self-reported)	1.8	2.1	2.3	-1.5	-1.4
Systolic Blood Pressure	1.7	8.4	15.0	1.4	3.9
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.9	7.2	-0.8	-2.7
Stomach or abdominal pain in last month	1.7	2.1	2.7	1.2	1.6
Had other major operations	1.7	2.0	2.7	1.2	1.6
Length of working week for main job	1.7	1.9	3.6	0.5	-1.9
Hypothyroidism/myxoedema (self-reported)	1.7	3.2	5.0	2.2	1.2
Handedness (chirality/laterality): Left-handed	1.7	2.0	3.9	-0.4	2.0
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	3.1	-0.6	-1.8
Impedance of arm (right)	1.6	7.4	9.1	3.0	2.4
Arm fat mass (right)	1.6	6.4	11.4	1.2	-3.4
Birth weight of first child	1.6	3.0	3.6	1.9	1.5
Neuroticism score	1.5	3.1	3.1	1.8	1.8
Breastfed as a baby	1.5	1.8	1.9	-1.3	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	4.0	2.0	-0.7
Loud music exposure frequency	1.5	1.7	2.1	1.1	1.5
Whole body fat mass	1.5	6.4	11.8	1.0	-3.4
Leg fat percentage (left)	1.5	5.5	11.0	-0.2	-3.3
Diabetes (father)	1.4	1.7	3.4	-0.3	-1.8
Body mass index (BMI)	1.4	6.2	12.3	-0.1	-3.5
Trunk fat mass	1.4	6.0	10.2	1.3	-3.2
Weight	1.4	6.9	13.2	0.8	-3.6
Worry too long after embarrassment	1.4	2.3	4.6	2.1	0.1
Friendships satisfaction	1.4	1.8	2.3	-1.5	1.1
Pain type(s) experienced in last month: Hip pain	1.4	1.8	2.5	1.6	-1.0
Basal cell carcinoma (self-reported)	1.4	1.7	2.7	0.8	1.6
Heart disease (siblings)	1.4	1.7	3.3	0.4	-1.8
Arm predicted mass (left)	1.4	7.0	13.9	-0.1	-3.7
Crohns Disease (2012)	1.3	2.1	3.8	1.9	-0.6
Taking other prescription medications	1.3	2.0	3.5	0.7	-1.9
Arm fat percentage (right)	1.3	5.2	8.3	1.4	-2.9
Ever highly irritable/argumentative for 2 days	1.3	1.6	2.5	1.6	0.8
Leg fat percentage (right)	1.3	4.8	9.7	-0.1	-3.1
Arm fat mass (left)	1.3	5.5	9.5	1.2	-3.1
Financial situation satisfaction	1.3	1.6	1.8	-1.3	-1.2
Arm fat-free mass (left)	1.3	6.5	13.0	0.0	-3.6
Respiratory disease	1.2	2.8	4.3	-2.1	-1.1
Medication: Metformin	1.2	1.6	2.5	-0.9	-1.6
Trunk fat percentage	1.2	4.9	7.1	1.6	-2.7
Alcohol intake versus 10 years previously	1.2	1.7	2.6	-0.9	-1.6
Medication for pain relief, constipation, heartburn	1.2	2.0	2.0	-1.4	1.4
Smoking status: Previous	1.2	1.7	3.5	1.9	0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.6	2.2	0.7
Supplements: Calcium	1.2	1.3	2.1	0.7	1.4
Depressed Affect (Nagel 2018)	1.1	2.2	3.6	1.9	0.9
Primary Biliary Cirrhosis	1.1	1.6	1.8	-1.3	1.2
Leg predicted mass (left)	1.1	5.6	10.5	0.8	-3.2
Prospective memory result	1.1	1.4	2.8	-0.0	-1.7
Lung cancer (father)	1.1	1.2	2.1	1.5	0.6
Peak expiratory flow (PEF)	1.1	2.5	4.9	2.2	-0.4
Body fat percentage	1.1	4.5	7.6	1.2	-2.8
Exposure to tobacco smoke outside home	1.1	1.5	1.6	-1.2	-1.3
Arm predicted mass (right)	1.1	5.5	11.0	-0.2	-3.3
Medication: Aspirin	1.1	1.4	2.5	-0.6	-1.6
Wears glasses or contact lenses	1.1	1.3	2.2	-1.5	-0.6
Alcohol drinker status: Never	1.1	1.3	2.6	-1.6	-0.2
Basal metabolic rate	1.1	6.0	11.8	0.5	-3.4
BMI	1.0	5.7	11.3	0.4	-3.4
Sensitivity / hurt feelings	1.0	1.8	2.7	1.6	0.9
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.2	1.5	0.7
Leg fat-free mass (left)	1.0	5.5	10.3	0.8	-3.2
High blood pressure (mother)	1.0	1.4	2.7	0.4	1.6
Waist circumference	1.0	3.6	3.8	1.9	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	4.2	2.1	1.5
Medication: Allopurinol	1.0	1.4	2.6	-1.6	-0.4
Arm fat percentage (left)	1.0	4.1	6.0	1.5	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.9	0.5	-1.4
Mineral and other dietary supplements	1.0	1.3	2.5	-1.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.0	3.8	0.5	2.0
Whole body water mass	1.0	5.7	11.2	0.2	-3.4
Leg predicted mass (right)	1.0	5.5	10.2	0.9	-3.2
Number of operations (self-reported)	1.0	1.4	2.8	1.7	0.3
Bipolar Disorder (2011)	0.9	0.8	1.7	-1.3	0.0
Serious illness, injury or assault to yourself	0.9	1.1	1.5	0.8	1.2
Past tobacco smoking	0.9	1.7	3.2	-1.8	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	1.5	1.2	1.2
Arm fat-free mass (right)	0.9	4.6	9.1	-0.2	-3.0
Number of full brothers	0.9	1.2	2.1	1.4	-0.5
Medication: Ibuprofen	0.9	1.1	1.8	0.6	-1.3
Suffer from ‘nerves’	0.9	1.5	2.0	1.0	1.4
Whole body fat-free mass	0.9	5.4	10.8	0.2	-3.3
Leg fat-free mass (right)	0.9	5.1	9.3	0.9	-3.1
Mood swings	0.9	1.6	2.2	1.5	1.0
Medication: Gliclazide	0.9	1.0	1.8	-0.5	-1.3
Mean Putamen Volume	0.8	0.9	1.3	-1.1	-0.8
Rheumatoid Arthritis	0.8	1.1	2.1	0.3	-1.5
Angina	0.8	1.0	1.4	0.8	1.2
Severe depression (siblings)	0.8	0.9	1.8	1.3	0.2
Impedance of leg (right)	0.8	3.7	6.7	0.9	2.6
Fed-up feelings	0.8	1.4	2.8	1.7	0.1
Trunk fat-free mass	0.8	4.6	9.2	-0.1	-3.0
Number of live births	0.8	1.1	2.1	1.4	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.3	0.8	-1.1
Trunk predicted mass	0.8	4.7	9.4	-0.1	-3.1
Number of children fathered	0.8	0.9	1.2	0.8	1.1
Shortness of breath walking on level ground	0.8	1.0	1.7	0.5	-1.3
Qualifications: College or University degree	0.8	2.6	3.5	-1.3	-1.9
Angina (self-reported)	0.8	1.1	1.6	0.7	1.3
Medication: Seretide 50 evohaler	0.8	0.9	1.8	-0.3	1.4
Knee pain experienced in last month	0.8	1.2	1.3	1.1	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	1.3	0.8	-1.2
Illnesses of father: Heart disease	0.8	1.1	1.2	-1.0	-1.1
Loneliness, isolation	0.8	1.1	1.4	1.2	0.8
Illnesses of father: None of the above (group 1)	0.8	1.0	1.8	0.5	1.3
Commuting to job workplace: Public transport	0.8	0.9	1.7	-1.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.0	1.0	-1.0
Worry (Nagel 2018)	0.7	1.4	2.8	0.3	1.7
Neuroticism	0.7	1.6	2.4	0.9	1.6
Hayfever, allergic rhinitis or eczema	0.7	1.5	2.7	0.5	1.6
Had major operations	0.7	0.8	1.4	0.5	-1.2
Medication for cholesterol	0.7	1.0	1.7	-1.3	-0.6
Medication: Aspirin	0.7	1.0	1.7	-0.5	-1.3
Number of self-reported non-cancer illnesses	0.7	1.1	2.0	0.5	-1.4
Miserableness	0.7	1.3	2.5	1.6	0.1
Ever smoked	0.7	1.2	1.6	1.3	0.8
Risk taking	0.7	1.0	1.5	0.7	1.2
Myopia	0.7	0.9	1.5	-1.2	-0.6
Pain experienced in last month	0.7	1.1	2.1	-0.3	1.5
Breast Cancer	0.6	1.4	2.1	1.4	0.8
Ovarian Cancer	0.6	0.9	1.5	0.4	1.2
HDL Cholesterol	0.6	1.0	1.6	0.6	1.3
Vitamin and mineral supplements	0.6	0.8	1.5	-1.2	-0.2
Pack years adult smoking proportion	0.6	0.9	1.6	0.3	-1.3
Townsend deprivation index at recruitment	0.6	0.9	1.3	-0.7	-1.1
Medication: Levothyroxine sodium	0.6	1.0	1.9	1.4	0.4
Impedance of leg (left)	0.6	3.0	5.3	0.8	2.3
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	3.7	1.9	0.6
Medication: Cholesterol lowering	0.6	0.9	1.7	-1.3	-0.3
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	0.8	0.9	0.9
Medication: Paracetamol	0.6	0.9	1.9	1.4	0.0
Eye problems/disorders: None of the above	0.6	0.7	0.8	-0.9	0.8
Medication: Omeprazole	0.6	0.7	0.8	0.8	-0.9
Leg pain on walking	0.6	0.8	1.5	1.2	0.0
Back pain experienced in last month	0.6	0.9	1.3	0.7	-1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.7	0.9	1.0	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.0	1.0	0.8
Pack years of smoking	0.6	0.9	1.8	-0.0	-1.3
HbA1C	0.5	0.5	0.9	0.9	-0.4
Lung FVC	0.5	2.4	4.1	-0.9	-2.0
Systolic blood pressure, automated reading	0.5	1.6	1.8	1.3	1.2
Multivitamins +/- minerals	0.5	0.6	1.2	1.1	0.1
Hair/balding pattern: Pattern 2	0.5	0.6	0.9	-0.6	1.0
Mouth/teeth dental problems	0.5	0.8	1.1	-0.7	-1.1
Tense / ‘highly strung’	0.5	0.9	1.5	0.5	1.2
Blood clot in the leg (DVT)	0.5	0.6	1.0	1.0	0.5
Comparative body size at age 10	0.5	1.4	2.7	0.4	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.2	-0.2	-1.1
Pulse rate, automated reading	0.5	1.7	2.8	-1.7	-0.7
Alcohol intake frequency.	0.5	1.1	2.0	-1.4	-0.5
Overall health rating	0.5	1.1	1.4	1.2	-0.9
Family relationship satisfaction	0.5	0.6	1.2	0.3	-1.1
Average weekly red wine intake	0.5	0.7	1.3	-1.1	-0.3
Long-standing illness, disability or infirmity	0.5	0.7	1.2	1.1	-0.4
Ever had bowel cancer screening	0.5	0.5	1.1	-1.0	0.1
Ever depressed for a whole week	0.5	0.6	1.0	1.0	0.6
Cholesterol lowering medication	0.5	0.8	1.0	-0.7	-1.0
Ulcerative Colitis (UC)	0.4	0.8	1.6	-1.3	0.1
Triglycerides	0.4	0.7	1.3	-1.1	-0.1
Blood White Count	0.4	2.9	5.7	-2.4	0.2
Number of treatments/medications taken	0.4	0.8	1.2	1.1	-0.6
Relative age of first facial hair	0.4	0.7	1.1	1.1	-0.6
Ever had hysterectomy (womb removed)	0.4	0.4	0.7	-0.8	0.3
Current tobacco smoking	0.4	0.6	1.2	1.1	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.9	1.0	-0.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	0.8	-0.2	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	0.8	0.6	0.9
Had menopause	0.4	0.5	0.8	0.5	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	0.6	0.8	0.7
Illnesses of mother	0.4	0.5	0.5	0.7	-0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	1.0	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.6	0.8	0.6
Emphysema/chronic bronchitis	0.4	0.4	0.8	-0.2	-0.9
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	0.9	0.4
Asthma (self-reported)	0.4	0.8	1.2	-0.7	-1.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.8	0.4	0.9
Alzheimer’s Disease (in mother)	0.3	0.4	0.8	-0.9	0.2
Alzheimer’s Disease (in father)	0.3	0.3	0.5	-0.7	0.3
Alzheimer’s Disease (including proxy)	0.3	0.5	0.9	-0.9	0.2
Age at First Birth	0.3	0.4	0.6	0.4	-0.8
Height	0.3	5.0	9.8	3.1	-0.5
Cardiovascular Disease	0.3	0.9	1.5	-0.4	1.2
Chronotype (morning person)	0.3	0.7	1.2	-1.1	0.3
Hand grip strength (left)	0.3	0.9	1.6	-1.2	0.5
Supplements: Zinc	0.3	0.4	0.7	-0.8	-0.2
Diabetes (mother)	0.3	0.4	0.8	0.9	-0.1
Maternal smoking around birth	0.3	0.5	0.8	0.9	-0.3
Qualifications: CSEs or equivalent	0.3	0.4	0.6	0.5	-0.8
Medication: Atenolol	0.3	0.4	0.8	-0.2	0.9
Sitting height	0.3	2.1	2.8	1.7	-1.2
Alcohol usually taken with meals	0.3	0.5	1.0	-1.0	-0.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	0.8	-0.4
Qualifications: None of the above	0.3	0.5	0.6	0.7	0.8
Medication: Ramipril	0.3	0.4	0.6	0.8	0.5
Illnesses of siblings	0.3	0.4	0.5	-0.7	0.6
Worrier / anxious feelings	0.3	0.6	0.9	0.6	1.0
Asthma	0.3	0.7	1.1	-0.5	-1.0
Depression (self-reported)	0.3	0.3	0.6	0.3	0.8
Headache pain in last month	0.3	0.6	0.9	0.5	-1.0
Birth weight	0.3	0.6	0.9	0.9	0.6
High blood pressure (siblings)	0.3	0.5	0.8	0.9	0.3
Forced vital capacity (FVC), Best measure	0.3	1.1	2.2	1.5	0.3
Wheeze or whistling in the chest in last year	0.3	0.6	1.1	1.1	0.3
Comparative height size at age 10	0.3	1.7	2.6	1.6	-0.9
Osteoporosis (self-reported)	0.3	0.4	0.6	-0.8	0.3
Smoking status: Current	0.3	0.5	0.9	0.9	0.4
Average weekly champagne plus white wine intake	0.3	0.4	0.7	-0.8	-0.3
Guilty feelings	0.3	0.4	0.8	-0.1	0.9
Hearing aid user	0.3	0.3	0.5	0.5	-0.7
Medication: Blood pressure	0.3	0.6	1.0	1.0	0.5
High cholesterol (Self-reported)	0.3	0.6	0.8	-0.9	0.6
Medication: Paracetamol	0.3	0.5	1.0	1.0	0.1
Illnesses of father: High blood pressure	0.3	0.4	0.8	0.9	0.1
Commuting to job workplace: Cycle	0.3	0.4	0.6	0.3	0.8
Bipolar Disorder (2018)	0.2	0.3	0.6	0.8	0.0
Depression (Nagel 2018)	0.2	0.2	0.3	0.6	0.3
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.0	-0.3	1.0
Crohns Disease (2017)	0.2	0.4	0.5	0.7	-0.5
Prostate Cancer	0.2	0.3	0.4	0.4	0.7
Body Mass Index (BMI) (2010)	0.2	0.3	0.5	0.3	-0.7
Schizophrenia (2014)	0.2	0.5	0.9	1.0	0.0
Blood Eosinophil Count	0.2	1.4	1.8	-1.4	1.0
Allergy or Eczema	0.2	0.5	0.9	-0.1	1.0
Hearing difficulty/problems: Yes	0.2	0.3	0.5	0.7	0.2
Average weekly fortified wine intake	0.2	0.2	0.4	0.2	0.6
Chronic bronchitis/emphysema (father)	0.2	0.3	0.4	0.6	0.4
Forced vital capacity (FVC)	0.2	0.7	1.1	1.1	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.7	0.8	0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.8	0.3	0.9
Standing height	0.2	2.2	4.3	2.1	-0.3
Hair/balding pattern: Pattern 4	0.2	0.4	0.7	0.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.3	-0.5	0.5
Glaucoma (self-reported)	0.2	0.3	0.3	0.6	0.4
Heart disease (mother)	0.2	0.3	0.5	0.1	0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.4	-0.7	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.6	-0.8	0.4
Mother’s age at death	0.2	0.3	0.5	0.7	0.2
Average weekly beer plus cider intake	0.2	0.3	0.5	0.7	0.3
Unable to work because of sickness or disability	0.2	0.3	0.5	0.3	-0.7
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.8	-0.4	-0.9
Alcohol drinker status: Previous	0.2	0.2	0.3	0.6	-0.1
Bipolar Disorder or Schizophrenia	0.1	0.2	0.5	0.7	0.0
Major Depression (MDD)	0.1	0.2	0.3	-0.6	0.0
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.4	0.0
Fasting Glucose	0.1	0.1	0.2	0.4	-0.2
LDL Cholesterol	0.1	0.2	0.2	-0.5	0.4
Hair Pigment	0.1	3.1	3.3	-1.7	-1.8
Tanning	0.1	1.7	1.8	1.2	1.4
Hand grip strength (right)	0.1	0.2	0.2	-0.5	0.5
Relative age voice broke	0.1	0.2	0.3	0.5	0.3
Age when periods started (menarche)	0.1	0.3	0.7	-0.8	0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.3	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.2	0.5
High blood pressure	0.1	0.2	0.3	0.3	0.5
Number of incorrect matches in round	0.1	0.2	0.2	-0.4	0.4
Heart attack	0.1	0.1	0.1	-0.1	-0.3
Allergy	0.1	0.1	0.3	-0.0	-0.5
Fluid intelligence score	0.1	0.3	0.5	-0.7	-0.2
Father’s age at death	0.1	0.1	0.2	0.1	-0.5
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	-0.4	0.4
Pulse rate	0.1	0.1	0.2	-0.2	-0.5
Happiness	0.1	0.2	0.3	0.2	-0.5
Noisy workplace	0.1	0.1	0.2	0.4	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.2	0.5	-0.3
Exposure to tobacco smoke at home	0.1	0.1	0.3	-0.5	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.1	0.3	-0.3
Health satisfaction	0.1	0.2	0.3	0.2	-0.6
Supplements: Vitamin C	0.1	0.2	0.2	0.4	-0.4
Qualifications: nursing, teaching	0.1	0.2	0.2	-0.3	-0.5
Commuting to job workplace: Walk	0.1	0.1	0.1	-0.4	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.1	0.3	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	-0.1	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.1	-0.4
Medication: Lisinopril	0.1	0.1	0.1	0.0	-0.4
Medication: Atorvastatin	0.1	0.1	0.2	0.5	0.0
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Schizophrenia (2018)	0.0	0.0	0.1	0.3	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	0.3	0.0
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	-0.3	-0.4
Reaction Time	0.0	0.1	0.1	-0.2	-0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.1	-0.3	0.2
Lupus	0.0	0.1	0.1	-0.2	0.3
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.1	0.0
Ulcerative Colitis	0.0	0.0	0.0	-0.1	0.0
Time employed in main current job	0.0	0.0	0.0	-0.2	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.1	0.1	0.1	0.3
Medication: Lansoprazole	0.0	0.0	0.0	0.1	0.0
Medication: Amlodipine	0.0	0.1	0.1	0.2	-0.2
Neck or shoulder pain in last month	0.0	0.1	0.1	-0.2	-0.3
Medication: Blood pressure	0.0	0.1	0.1	-0.2	0.3
Mean time to correctly identify matches	0.0	0.1	0.1	0.0	-0.3
Chest pain or discomfort	0.0	0.0	0.0	-0.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	-0.0	-0.1
Hypertension (Self-reported)	0.0	0.0	0.1	0.3	-0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.1	0.0	-0.3
Eye problems/disorders: Cataract	0.0	0.0	0.0	0.2	-0.2
Ever taken oral contraceptive pill	0.0	0.0	0.0	-0.1	-0.0
Medication: Bendroflumethiazide	0.0	0.1	0.1	-0.4	0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.0	0.2	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.2	0.5	0.0

Hub : Genes

CEBPA

Models

Trait associations