Hub : Genes

CEP170B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1980 0.0640 1.3e-04 0.085 NA 0.073 NA 0.088 1.9e-07 NA 1.3e-06 NA 1.1e-07
2 GTEx Brain Cortex 0.2360 0.0980 9.7e-03 -0.011 NA 0.016 NA -0.008 9.8e-01 NA 1.2e-01 NA 5.9e-01
3 GTEx Cells Transformed fibroblasts 0.1590 0.0540 2.8e-04 0.039 NA 0.084 NA 0.071 6.5e-04 NA 6.9e-07 NA 5.4e-06
4 GTEx Esophagus Mucosa 0.1650 0.0550 5.5e-04 0.103 NA 0.097 NA 0.080 2.4e-07 NA 5.0e-07 NA 5.1e-06
5 GTEx Lung 0.1706 0.0537 4.6e-04 0.040 NA 0.059 NA 0.035 4.5e-04 NA 2.7e-05 NA 1.0e-03
6 GTEx Thyroid 0.2890 0.0540 3.1e-09 0.127 NA 0.104 NA 0.094 6.5e-10 NA 2.4e-08 NA 1.1e-07
7 GTEx Whole Blood 0.1380 0.0540 1.2e-03 0.056 NA 0.116 NA 0.118 7.0e-06 NA 7.8e-11 NA 6.0e-11
8 METSIM Adipose 0.0632 0.0238 1.4e-04 0.024 0.019 0.023 0.02 0.012 1.5e-04 0.00069 2.0e-04 4e-04 5.2e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 2.6 4.1 6.6 -1.9 1.3 -1.4 -2.2 -1.9 -2.6 -2.2 -2.3
Bipolar Disorder or Schizophrenia 0.6 1.4 6.0 -0.8 2.4 -0.7 -0.5 0.2 -0.5 -0.7 -1.7
Depressed Affect (Nagel 2018) 0.5 1.1 3.3 -1.0 1.8 -1.5 -0.1 1.1 1.0 -0.4 -0.3
Depression (Nagel 2018) 1.8 2.7 13.8 -0.7 3.7 -2.2 -0.1 0.9 1.0 -0.7 -0.4
Intelligence (Savage-Jansen 2018) 0.2 0.6 2.2 0.4 -0.3 0.6 -1.0 -0.9 -1.5 0.1 -0.1
Neuroticism (Nagel 2018) 0.3 0.7 1.5 -1.2 0.8 -0.9 -0.4 0.6 0.1 -1.1 -0.8
Schizophrenia (2018) 0.6 1.2 3.0 0.5 1.7 0.2 1.0 1.7 1.2 0.8 -0.2
Schizophrenia vs Biploar Disorder 1.2 1.5 4.6 1.7 0.0 0.0 2.1 0.0 0.0 1.6 1.5
Worry (Nagel 2018) 0.5 1.1 2.9 -1.4 -0.1 -0.5 -0.7 -0.4 -0.8 -1.5 -1.7
Alzheimer’s Disease (in mother) 4.0 4.7 8.8 -1.3 -0.9 -1.1 -3.0 -1.8 -2.6 -3.0 -2.5
Alzheimer’s Disease (in father) 1.4 1.5 4.4 -0.6 0.9 -0.5 1.2 2.1 2.0 0.6 0.6
Alzheimer’s Disease (including proxy) 1.0 1.4 3.3 -1.2 -0.2 -1.3 -1.6 0.2 -0.6 -1.8 -1.4
Crohns Disease (2017) 0.2 0.5 1.3 0.8 0.2 -0.8 -0.6 0.5 -0.9 0.6 1.2
Irritable Bowel Disease (IBD) 0.8 2.0 5.8 -0.3 0.5 -1.7 -2.4 -1.2 -2.1 -0.9 -0.8
Ulcerative Colitis (UC) 1.8 3.4 7.7 -0.6 -0.3 -1.2 -2.8 -2.2 -2.0 -1.7 -2.3
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.7 1.4 3.5 -1.2 0.8 -1.8 -0.6 -0.7 -0.5 -1.9 -1.1
Verbal and Numeric Reasoning (VNR) 0.4 0.9 2.5 0.1 0.1 -0.6 -1.0 -0.7 -1.6 -0.9 -1.5
Breast Cancer 3.9 9.4 23.2 -2.5 -0.6 -1.4 -3.5 -4.8 -4.1 -3.0 -2.2
Ovarian Cancer 0.2 0.3 0.8 -0.6 -0.0 -0.9 -0.2 -0.1 0.5 -0.7 0.2
Prostate Cancer 0.9 1.3 5.5 2.3 -1.1 1.1 -0.9 -0.9 -0.8 -0.1 0.4
Age at First Birth 0.1 0.2 0.7 -0.1 0.1 0.7 -0.1 0.9 0.2 0.2 -0.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.1 1.5 4.6 2.1 1.3 -0.5 -1.6 0.0 -1.8 0.1 0.1
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.4 0.7 2.4 0.6 1.4 -0.5 0.0 0.0 -1.6 0.0 0.8
Mean Putamen Volume 1.0 1.1 3.5 -0.6 0.5 -1.1 -0.8 -0.7 -0.6 -1.5 -1.9
Fasting Glucose 0.2 0.2 0.6 -0.1 -0.8 0.8 0.1 0.2 0.5 0.3 0.3
HbA1C 0.4 0.5 1.3 -0.6 0.0 -0.3 -1.1 -0.9 -1.0 -0.5 -0.1
HDL Cholesterol 1.0 1.7 7.4 1.2 -1.4 0.5 -0.2 -1.4 -0.1 -0.9 -2.7
LDL Cholesterol 0.5 0.8 2.5 0.5 1.6 0.8 1.1 0.2 0.7 1.1 0.3
Lupus 0.3 0.4 2.1 0.9 -0.0 0.5 0.2 -1.5 -0.5 0.1 0.2
Neuroticism (2016) 0.5 0.7 1.4 -0.2 0.8 0.0 -1.1 -0.8 -1.2 -0.5 -1.2
Primary Biliary Cirrhosis 0.8 1.2 6.3 2.5 -0.9 -0.5 -0.3 1.2 0.2 -0.6 -0.3
Rheumatoid Arthritis 0.3 0.5 1.6 0.6 -0.4 -0.7 -0.2 1.1 0.0 -1.2 -0.2
Schizophrenia (2014) 0.8 1.9 4.7 1.3 1.3 0.3 1.8 2.2 1.5 1.3 0.1
Triglycerides 0.4 0.6 2.9 -1.7 1.2 -0.7 -0.1 -0.0 -0.3 -0.3 0.2
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 2.3 3.4 7.3 -0.3 1.8 -1.6 -2.1 -1.7 -1.9 -1.7 -2.7
Blood Eosinophil Count 0.1 1.0 2.5 -1.4 1.6 -0.8 0.5 -0.2 0.7 -0.4 1.6
Blood Platelet Count 1.4 16.0 57.5 -7.2 7.6 -1.4 -0.5 -1.8 -2.5 -1.8 1.7
Blood Red Count 0.6 5.9 27.2 0.1 5.2 2.1 2.5 1.0 2.0 1.8 1.0
Blood White Count 0.9 6.9 19.1 -4.4 2.6 -2.2 -1.8 -2.8 -2.9 -2.2 0.9
Heel T-Score 0.1 0.9 2.9 -0.4 -0.7 -1.2 -0.9 -0.9 0.1 -1.7 -0.8
BMI 0.3 1.7 3.8 -0.3 1.9 -1.1 1.8 1.2 0.8 0.1 1.9
Height 0.2 3.7 18.0 -1.7 1.4 -0.8 -0.1 -1.0 -0.2 -2.3 -4.2
Waist Hip Ratio (WHR) 0.2 0.8 3.2 -1.2 1.8 -0.6 0.5 -0.5 0.5 -0.0 0.8
Systolic Blood Pressure 0.2 0.9 3.0 -1.4 -0.8 0.6 -0.3 -1.7 -0.6 -0.4 0.7
Smoking Status 3.0 7.1 15.7 1.7 1.2 1.9 4.0 2.3 2.2 3.7 3.0
Allergy or Eczema 0.3 0.7 2.1 0.1 0.5 1.1 1.4 0.7 0.2 0.5 -1.1
Cardiovascular Disease 0.9 3.0 8.2 -2.1 -1.2 -1.3 -1.0 -2.2 -0.7 -2.9 -1.4
Hypothyroidism (self reported) 0.8 1.7 10.0 0.7 -3.2 0.2 1.0 -1.0 -1.0 0.4 0.4
Respiratory disease 2.1 4.6 8.5 1.3 -2.2 1.9 2.9 1.5 1.6 2.9 2.3
Type 2 Diabetes (T2D) (2018) 0.6 1.1 4.2 -0.5 -0.4 -2.0 0.3 -0.6 0.1 -2.0 0.0
Lung FEV1/FVC ratio 1.0 5.1 9.7 -2.4 1.1 -2.0 -3.1 -2.6 -2.4 -2.2 -1.4
Lung FVC 0.8 4.2 13.2 -1.2 -1.6 -0.7 -2.3 -3.6 -2.8 -0.8 -1.5
Neuroticism 0.2 0.4 1.3 -0.4 0.5 0.2 0.5 0.8 1.1 -0.2 -0.6
Chronotype (morning person) 0.6 1.3 4.7 0.2 -0.5 1.5 -0.4 -1.2 -2.2 1.2 0.2
Hair Pigment 0.5 13.0 25.4 -0.4 -0.2 -3.2 -5.0 -4.0 -4.1 -4.5 -3.9
Tanning 0.2 2.6 8.5 2.9 -1.4 2.7 1.0 -0.3 -0.3 1.3 -0.0
Hand grip strength (left) 0.4 1.2 5.7 0.4 1.2 1.1 -0.2 -2.4 -0.4 0.5 -0.4
Number of treatments/medications taken 0.6 1.0 3.6 -0.2 -1.4 -0.1 1.9 0.8 0.9 -0.2 1.0
Average weekly spirits intake 2.1 2.7 8.3 -1.6 0.4 -2.9 -0.6 -1.4 -0.8 -1.9 -1.9
Sensitivity / hurt feelings 0.4 0.7 2.5 1.1 1.6 0.6 -0.3 -0.7 -0.8 0.5 0.1
Frequency of depressed mood in last 2 weeks 1.6 2.2 8.7 -1.1 2.9 -2.3 -0.6 0.7 0.1 -1.3 -0.1
Hearing difficulty/problems: Yes 0.4 0.7 2.8 0.4 1.7 0.7 -0.4 -0.1 -1.1 0.2 0.6
Relative age of first facial hair 0.5 1.1 2.7 -1.4 1.2 0.2 -0.9 -1.6 -1.2 -0.3 -0.3
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 4.4 0.3 -2.1 0.5 -0.7 -1.4 -1.3 -0.4 -0.2
Ever used hormone-replacement therapy (HRT) 1.5 1.9 6.5 0.7 -2.0 -2.5 -0.4 0.4 -0.4 -1.6 -0.7
Ever had hysterectomy (womb removed) 1.4 1.6 5.1 2.0 -0.4 0.1 0.7 2.3 1.0 0.9 1.2
Systolic blood pressure, automated reading 0.1 0.3 1.1 -1.1 -0.3 0.0 0.2 -0.6 -0.1 -0.6 0.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.0 0.5 1.0 -0.2 -0.5 -0.5 0.1 -0.7 0.8
Angina 0.9 1.2 3.1 0.6 -0.9 -0.5 1.0 1.7 1.7 0.3 1.1
Medication for hormone replacement therapy 0.6 0.6 1.7 0.7 -1.3 -0.3 1.1 1.0 0.7 -0.2 -0.0
Vitamin and mineral supplements 1.0 1.3 3.9 0.9 0.2 -1.0 -1.1 -0.5 -0.2 -1.8 -2.0
Supplements: Zinc 0.3 0.3 0.8 -0.4 -0.3 -0.3 -0.5 -0.6 -0.0 -0.9 -0.8
Medication: Co-codamol 0.7 0.8 1.5 -1.2 -0.4 -1.0 1.1 1.2 0.4 -1.2 -0.1
Medication: Metformin 0.6 0.8 2.0 -1.1 -0.2 -1.1 0.4 0.8 0.6 -1.4 1.0
Diabetes (father) 1.0 1.2 5.2 -0.5 2.3 0.2 -0.3 0.1 -0.9 0.6 1.6
Diabetes (mother) 1.9 2.4 7.4 -2.7 2.0 -2.2 -0.3 -0.4 0.2 -1.7 0.0
Severe depression (siblings) 0.4 0.5 1.9 0.1 0.5 -1.1 0.5 0.7 1.4 0.1 0.0
Pack years adult smoking proportion 1.6 2.4 4.0 -1.6 1.6 -1.2 -1.2 -1.8 -1.4 -1.5 -2.0
Impedance of leg (right) 0.3 1.4 3.5 0.5 -1.2 1.8 -1.9 -0.4 -1.1 -0.7 -0.7
Leg fat-free mass (left) 0.3 1.6 5.9 -0.5 1.3 -0.9 2.4 1.0 1.7 0.2 0.3
Trunk fat percentage 0.3 1.1 3.0 -0.8 0.8 -0.0 1.3 1.7 1.2 -0.8 0.9
Hand grip strength (right) 0.6 1.6 8.2 -0.0 1.8 0.8 -0.4 -2.9 -0.6 0.5 -0.2
Townsend deprivation index at recruitment 0.6 0.8 2.0 0.9 -1.4 1.2 -0.5 -0.8 -0.6 0.7 0.6
Current tobacco smoking 0.9 1.4 7.0 -1.2 2.6 -0.4 1.3 -0.0 -0.3 0.8 0.5
Average weekly fortified wine intake 0.8 0.9 2.1 -0.5 0.1 -0.9 -1.4 -1.1 -1.5 -1.0 -0.2
Maternal smoking around birth 0.9 1.3 2.5 0.8 -1.0 1.6 1.0 1.1 0.6 1.3 1.5
Fed-up feelings 0.9 1.6 6.0 -0.4 1.9 -2.4 -0.1 1.1 1.3 -0.8 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 6.1 -1.4 2.5 -1.3 -0.1 0.2 1.4 -0.2 0.6
Relative age voice broke 2.1 3.2 8.5 -1.2 0.1 -0.2 -2.9 -2.9 -2.5 -1.0 -0.4
Taking other prescription medications 0.9 1.4 6.5 -0.4 -2.5 0.5 1.5 0.8 1.0 0.1 0.8
Age when periods started (menarche) 0.2 0.5 2.4 0.3 -1.0 1.5 0.5 -0.2 0.4 0.3 0.5
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 5.7 2.2 -1.0 0.3 0.8 1.6 1.5 1.4 2.4
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 5.7 -1.2 -0.6 -1.1 -2.2 -1.2 -1.4 -2.4 -0.7
Tinnitus: Yes, but not now, but have in the past 0.9 0.9 2.0 -0.2 1.1 0.9 0.7 1.4 1.0 1.0 1.1
Qualifications: CSEs or equivalent 0.6 0.8 2.2 -0.5 0.6 -0.6 0.6 1.2 1.5 0.1 1.1
Serious illness, injury or assault to yourself 0.1 0.1 0.6 0.1 0.0 -0.5 -0.3 -0.0 0.0 -0.8 -0.1
High blood pressure 0.5 1.3 3.1 -1.7 -1.6 -0.7 0.4 -0.1 1.0 -1.8 -0.3
Hayfever, allergic rhinitis or eczema 0.5 1.2 4.9 -0.4 1.6 0.6 0.1 -0.7 -0.9 -0.2 -2.2
Multivitamins +/- minerals 1.3 1.6 4.0 -0.4 1.0 0.9 1.6 0.6 0.7 1.9 2.0
Stomach or abdominal pain in last month 0.9 1.1 4.1 -1.4 0.1 -1.5 0.8 0.4 2.0 -0.1 0.0
Supplements: Glucosamine 0.1 0.2 0.8 -0.1 0.9 0.1 0.0 -0.3 -0.2 0.6 0.2
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 2.3 1.4 -0.9 -0.3 1.5 1.0 0.8 0.1 0.0
Medication: Atenolol 0.6 0.8 1.3 1.1 -0.9 -0.9 1.0 1.1 0.6 0.4 0.5
Medication: Levothyroxine sodium 1.2 2.0 10.0 -0.4 -3.2 -0.9 -0.4 -1.3 -1.4 -1.0 -0.8
Sitting height 0.1 0.9 2.3 -0.9 1.0 -0.0 0.7 -1.0 1.3 -0.3 -1.5
Chronic bronchitis/emphysema (father) 2.0 2.3 6.2 2.5 -0.9 0.7 2.0 1.9 1.3 1.0 1.0
High blood pressure (mother) 0.7 1.0 4.5 -0.9 -2.1 -0.8 -0.4 -0.8 -0.5 -0.9 -0.6
Body mass index (BMI) 0.5 2.0 4.1 -0.4 1.4 -0.9 2.0 2.0 1.5 0.1 1.7
Impedance of leg (left) 0.3 1.3 4.9 0.1 -1.0 2.2 -1.7 -0.5 -1.0 -0.3 -0.7
Leg predicted mass (left) 0.3 1.7 5.9 -0.4 1.4 -1.0 2.4 1.1 1.7 0.2 0.3
Trunk fat mass 0.3 1.3 3.0 -0.9 1.2 -0.2 1.7 1.7 1.4 -0.6 0.6
Waist circumference 0.5 2.0 5.4 -0.5 1.6 -0.3 2.3 1.6 1.8 0.3 1.3
Number of incorrect matches in round 0.3 0.5 1.6 0.7 -0.2 1.0 -1.3 -0.8 -0.2 0.0 0.1
Past tobacco smoking 5.6 10.3 17.5 -3.2 1.2 -2.9 -3.9 -3.1 -3.0 -4.2 -3.5
Alcohol usually taken with meals 1.0 1.6 2.8 -0.3 1.6 -1.5 -1.7 -0.4 -1.6 -1.2 -0.9
Nervous feelings 0.6 1.2 3.7 -1.9 0.1 -0.5 -1.1 -1.2 -0.6 -1.3 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 2.7 0.1 0.7 0.0 0.2 1.5 0.5 0.4 1.6
Hearing difficulty/problems with background noise 1.0 1.6 3.8 -1.2 0.2 -0.6 -1.6 -1.4 -1.3 -1.9 -1.1
Hair/balding pattern: Pattern 2 1.4 1.8 5.4 -0.3 0.4 -2.3 -1.4 -0.1 -0.3 -2.1 -1.5
Had menopause 1.4 1.8 4.4 -0.0 -2.1 -1.8 0.3 0.0 0.3 -1.7 -1.9
Had other major operations 0.5 0.6 1.6 -0.5 -1.3 -0.5 1.0 1.1 0.7 0.1 -0.1
Forced vital capacity (FVC) 0.6 2.3 6.1 -1.7 0.4 -0.6 -1.8 -2.5 -1.4 -1.2 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 1.1 2.5 6.2 -1.8 -0.6 -1.4 -2.2 -1.1 -1.3 -2.5 -0.4
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 2.5 0.8 1.6 -1.4 0.9 1.5 1.6 -0.6 0.2
Qualifications: None of the above 0.4 0.8 2.0 -0.1 -0.6 0.4 0.9 1.4 0.6 1.4 1.0
Financial difficulties in last 2 years 0.2 0.2 0.6 0.0 0.5 -0.4 0.3 -0.4 0.5 0.8 0.5
Mouth/teeth dental problems 0.6 0.9 5.3 -0.3 2.3 0.2 -0.0 -0.1 -0.5 0.5 1.2
Heart attack 0.8 1.0 1.7 1.3 -1.2 -0.2 0.8 1.0 1.1 1.0 1.0
Allergy 0.5 1.2 4.8 -0.5 -0.6 -1.1 -2.2 -0.4 -0.9 -1.2 0.3
Pain all over the body in last month 0.5 0.5 2.5 -0.6 0.4 -1.6 0.1 0.4 0.4 -0.7 0.5
Diabetes (self-reported) 0.5 0.7 1.4 0.4 -0.6 -0.7 1.0 1.2 1.0 -0.7 0.9
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 2.8 -1.7 0.5 -0.6 0.4 1.0 0.5 -0.1 -0.8
Medication: Ramipril 0.3 0.4 1.8 -0.8 -1.3 -0.1 -0.6 -0.5 -0.5 -0.3 0.2
Medication: Simvastatin 0.7 1.0 2.7 1.3 0.1 -0.0 1.6 1.2 1.4 -0.3 0.7
Fluid intelligence score 0.2 0.3 0.8 -0.4 -0.3 0.4 0.7 0.1 -0.6 0.8 0.9
Illnesses of siblings 0.2 0.2 1.3 0.2 -0.5 1.1 0.3 -0.4 0.0 0.1 -0.3
Neuroticism score 0.3 0.6 1.4 -0.6 1.1 -0.8 -0.4 -0.1 0.4 -1.1 -1.2
Weight 0.4 1.7 4.3 -0.9 1.8 -0.6 2.1 1.5 1.6 -0.2 0.5
Impedance of arm (right) 0.6 2.6 5.6 -0.5 -2.4 0.7 -2.4 -1.2 -1.2 -1.9 -1.6
Arm fat percentage (right) 0.2 0.9 2.8 -0.7 0.3 -0.7 0.9 1.7 1.0 -1.0 0.9
Trunk fat-free mass 0.2 1.0 4.8 -0.2 1.2 -0.3 2.2 0.4 1.1 0.7 -0.3
Hip circumference 0.2 1.0 1.8 -1.3 1.1 -0.4 1.2 1.3 1.0 -0.8 -0.2
Time employed in main current job 0.5 0.6 2.9 0.8 -1.7 -0.5 0.1 -0.4 -0.2 -0.4 -1.0
Alcohol intake versus 10 years previously 0.4 0.6 2.3 -0.1 -0.9 -0.1 0.4 0.7 0.5 0.8 1.5
Father’s age at death 0.6 0.8 2.6 0.5 1.6 0.2 0.3 0.4 -0.1 1.6 0.7
Worrier / anxious feelings 0.6 1.1 2.8 -0.3 -0.3 -0.6 -1.0 -0.9 -1.2 -1.7 -1.6
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.9 2.7 -1.6 0.6 -1.2 -0.5 0.3 0.4 -1.1 0.9
Falls in the last year 0.7 1.0 5.4 -2.3 -0.2 -0.6 0.7 0.3 1.0 -0.1 0.7
Hair/balding pattern: Pattern 3 0.5 0.7 5.2 0.0 -2.3 0.1 0.0 -0.2 -0.1 -0.3 -0.6
Number of live births 0.2 0.4 0.9 -0.1 0.5 -0.9 0.4 1.0 -0.1 -0.1 -0.8
Forced expiratory volume in 1-second (FEV1) 1.2 3.9 8.5 -2.1 0.7 -1.3 -2.5 -2.9 -2.0 -1.6 -1.8
Pulse rate 4.1 6.9 16.3 0.6 0.8 1.0 3.7 4.0 3.6 2.6 1.9
Happiness 1.1 1.4 8.4 -0.1 2.9 0.2 1.0 0.5 0.5 0.2 0.9
Noisy workplace 0.8 1.0 3.2 -1.1 0.8 -0.8 1.3 0.4 1.8 0.3 0.7
Qualifications: A levels/AS levels or equivalent 1.8 3.9 7.7 -1.3 -0.8 0.1 -2.8 -2.7 -2.5 -1.9 -1.9
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.1 3.1 -1.1 1.8 -1.1 1.4 0.4 0.9 0.2 0.4
Mouth/teeth dental problems: Dentures 1.6 2.7 16.6 1.0 -4.1 -0.3 1.1 0.7 1.2 -0.4 -0.9
Asthma 2.2 4.3 9.7 1.1 -0.4 1.9 3.1 1.2 2.0 2.8 2.5
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.2 0.5 1.5 0.8 -0.5 -1.3 -0.9 0.4 0.2
Medication: Cholesterol lowering 0.5 0.7 2.9 1.7 -0.7 -0.6 0.5 1.2 0.3 -0.5 0.3
Depression (self-reported) 0.4 0.5 1.4 -0.8 -0.0 -1.2 -0.3 -0.3 -0.7 -0.7 -0.8
Medication: Lansoprazole 0.5 0.6 2.5 -1.6 -1.2 0.1 -0.2 -0.4 -0.5 0.2 0.1
Prospective memory result 0.9 1.1 4.8 -2.2 1.6 -0.7 -0.2 -0.7 -0.1 -0.4 0.3
Lung cancer (father) 2.4 2.8 10.0 1.1 1.9 -1.0 1.6 2.0 3.2 -0.0 0.4
Illnesses of mother 0.6 0.7 1.5 0.6 0.7 1.1 1.0 -0.9 0.5 1.2 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.7 9.4 -2.0 0.5 -1.5 -3.1 -3.1 -2.7 -1.5 -1.7
Pulse wave Arterial Stiffness index 2.9 3.4 8.0 1.0 -0.1 1.1 2.3 2.8 2.4 1.8 1.7
Impedance of arm (left) 0.3 1.6 4.1 0.0 -2.0 0.9 -1.8 -0.7 -0.7 -1.5 -1.3
Arm fat mass (right) 0.3 1.4 3.0 -0.7 1.2 -0.9 1.5 1.7 1.3 -0.7 0.9
Trunk predicted mass 0.2 1.0 4.9 -0.1 1.1 -0.3 2.2 0.4 1.1 0.8 -0.3
Standing height 0.1 1.4 7.2 -0.9 1.0 0.5 0.4 -1.1 0.2 -0.7 -2.7
Length of working week for main job 0.5 0.6 1.7 -0.4 -0.1 -1.2 -0.6 -0.6 -0.2 -1.3 -0.8
Exposure to tobacco smoke at home 1.1 1.2 3.2 -1.0 -0.6 -0.4 -0.5 -1.6 -1.2 -1.1 -1.8
Breastfed as a baby 0.7 0.8 4.5 -1.3 2.1 -0.2 -0.2 0.3 0.5 -0.1 -0.0
Tense / ‘highly strung’ 0.6 1.0 4.6 1.2 -0.1 2.1 -1.0 -0.5 -0.6 0.4 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 0.9 0.4 -1.0 -0.8 -0.3 -0.9 -0.2 -0.9 -0.7
Hair/balding pattern: Pattern 4 2.1 5.2 19.3 2.1 -1.4 4.4 1.3 0.7 0.5 2.6 2.5
Birth weight of first child 0.1 0.2 1.0 0.5 -0.6 1.0 0.2 -0.1 -0.2 -0.1 0.0
Peak expiratory flow (PEF) 0.3 0.8 1.6 -0.5 1.1 -0.4 -0.9 -1.1 -1.2 0.2 -0.8
Pulse wave reflection index 0.2 0.2 0.9 -0.3 -0.1 -0.5 0.5 0.2 1.0 -0.4 0.3
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.0 0.2 0.9 0.4 1.0 0.6 0.7 1.0 1.0
Loud music exposure frequency 0.7 0.8 1.8 0.6 -0.3 -0.2 -1.1 -1.0 -0.9 -1.3 -1.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 2.5 -1.6 1.5 -0.7 -0.4 -1.0 -0.2 -1.0 -1.0
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 2.8 -0.8 1.1 -0.9 -1.1 -1.4 -1.0 -1.2 -1.7
Blood clot in the leg (DVT) 0.2 0.3 0.5 0.5 -0.5 -0.2 0.7 0.4 0.7 0.6 0.5
Medication: Paracetamol 0.4 0.6 1.3 -0.9 0.7 -0.9 0.4 0.1 1.1 -0.4 1.0
Headache pain in last month 0.4 0.6 2.0 -0.4 0.5 -1.4 -0.6 -0.1 0.8 -1.2 -0.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.8 -0.8 1.3 0.1 -0.9 -0.5 -0.2 0.5 -0.1
Glaucoma (self-reported) 0.2 0.2 1.2 1.1 0.2 -0.2 0.2 0.6 0.3 0.2 -0.4
Gout (self-reported) 0.9 1.2 2.8 0.1 0.0 0.9 1.7 0.3 1.6 1.5 1.2
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 15.1 0.2 -3.9 -0.4 -0.4 -2.0 -1.9 -0.8 -0.6
Medication: Amlodipine 1.2 1.7 5.2 -0.0 -2.3 -1.2 -1.6 -0.8 -1.7 -0.9 0.3
Medication: Ventolin 100micrograms inhaler 2.6 3.3 7.1 1.5 -0.2 1.7 2.7 1.5 1.6 2.4 1.9
Birth weight 0.6 1.2 2.5 1.3 1.6 0.6 1.1 0.7 1.6 1.0 -0.1
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.0 1.2 -0.5 1.2 -0.0 1.4 1.2 0.5 1.3
High blood pressure (siblings) 0.9 1.3 2.5 -0.9 0.7 -1.6 -1.5 -1.1 -1.0 -1.3 -0.8
Forced vital capacity (FVC), Best measure 0.7 2.7 5.6 -1.9 0.6 -1.0 -2.2 -2.4 -1.8 -1.0 -1.4
Body fat percentage 0.3 1.2 4.0 -0.8 0.6 -0.0 1.2 2.0 1.3 -0.7 1.1
Leg fat percentage (right) 0.5 1.7 6.4 -0.3 0.5 -0.0 1.5 2.5 1.6 -0.4 1.5
Arm fat-free mass (right) 0.3 1.5 5.3 -0.4 1.9 -0.4 2.3 0.8 1.2 0.7 0.2
Exposure to tobacco smoke outside home 0.2 0.3 0.9 -0.8 0.0 -0.9 0.1 -0.5 -0.9 -0.1 0.3
Comparative body size at age 10 0.3 0.7 1.7 -0.7 0.9 -1.3 1.2 -0.1 0.8 0.5 0.0
Number of full brothers 0.2 0.2 0.6 0.5 -0.1 -0.4 -0.2 -0.3 -0.3 -0.6 -0.8
Worry too long after embarrassment 0.2 0.4 1.8 0.5 -1.4 0.8 -0.0 0.5 -0.0 -0.1 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.0 -0.5 -1.0 -0.8 0.4 0.5 0.5 -0.6 0.0
Wheeze or whistling in the chest in last year 3.7 6.6 17.3 0.4 -0.7 1.6 4.2 3.0 3.4 2.4 2.4
Number of children fathered 1.4 1.6 4.4 0.5 1.0 -2.1 1.5 0.9 1.6 -0.7 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.7 2.9 -0.8 -0.1 -1.1 -1.4 -1.6 -1.1 -1.7 -1.7
Age at first live birth 0.4 0.8 3.8 -1.9 0.1 -0.4 -0.6 -1.2 -0.1 -0.5 0.1
Pulse wave peak to peak time 3.5 4.1 9.5 -1.0 0.2 -1.0 -2.6 -3.1 -2.7 -1.9 -2.0
Health satisfaction 1.1 1.4 3.0 -0.1 1.7 -1.1 1.7 1.4 1.4 -0.2 0.3
Shortness of breath walking on level ground 0.0 0.0 0.1 0.1 0.3 -0.2 -0.2 0.2 -0.2 0.1 0.3
Qualifications: College or University degree 1.3 4.1 8.5 -0.4 -0.1 -1.3 -2.8 -2.1 -2.5 -2.1 -2.9
Eye problems/disorders: None of the above 0.7 0.9 3.2 -1.4 0.4 -0.8 -0.6 -0.0 -0.5 -0.5 -1.8
Mouth/teeth dental problems: Loose teeth 1.5 1.7 5.8 0.1 -2.4 -2.0 -0.5 -0.5 0.1 -1.6 -0.9
Emphysema/chronic bronchitis 0.3 0.4 1.6 -1.3 0.6 -0.2 0.0 -0.1 0.9 0.5 0.4
Medication for pain relief, constipation, heartburn 0.6 1.0 2.4 1.1 -0.0 1.4 0.4 1.4 0.7 1.6 0.2
Neck or shoulder pain in last month 0.9 1.3 3.5 -1.0 0.3 -0.1 0.9 1.5 1.9 1.0 1.5
Medication: Blood pressure 0.4 0.7 1.9 0.7 -1.3 -0.5 1.4 0.7 1.0 -0.6 0.2
Angina (self-reported) 0.9 1.2 2.7 0.7 -0.9 -0.3 1.2 1.4 1.6 0.5 1.2
Migraine (self-reported) 0.2 0.3 0.9 -0.0 0.9 -0.7 -0.1 -0.0 -0.3 -0.7 -0.3
Medication: Ibuprofen 0.4 0.4 1.0 0.8 0.8 0.7 -0.5 -1.0 -0.6 0.3 0.3
Medication: Allopurinol 0.1 0.2 0.7 -0.8 0.8 -0.1 0.4 -0.1 0.3 -0.1 0.1
Medication: Omeprazole 1.3 1.6 4.4 -2.1 -1.0 -0.8 -0.2 -0.1 -0.2 -1.9 -1.8
Medication: Seretide 50 evohaler 1.1 1.3 3.7 0.4 -0.9 1.2 0.8 0.3 1.3 1.9 1.2
Mean time to correctly identify matches 1.1 2.0 5.4 -1.5 0.5 -2.2 -0.9 -0.8 -0.7 -2.3 -1.3
Heart disease (mother) 1.6 2.0 4.3 1.4 0.2 1.0 1.7 2.1 1.9 1.0 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.8 -0.4 -0.1 0.3 -0.1 -0.3 -0.9 -0.2 -0.1
Whole body fat mass 0.3 1.3 2.9 -1.1 1.0 -0.4 1.7 1.7 1.4 -0.5 0.8
Leg fat mass (right) 0.5 2.1 5.9 -0.2 1.2 -0.2 2.0 2.4 1.8 -0.0 1.3
Arm predicted mass (right) 0.3 1.7 6.0 -0.3 2.0 -0.6 2.4 0.9 1.4 0.7 0.2
Pulse rate, automated reading 2.1 6.9 10.6 1.0 -1.3 2.7 3.3 2.6 2.6 3.2 3.2
Alcohol intake frequency. 0.0 0.0 0.1 -0.0 -0.1 -0.3 -0.1 0.2 0.1 0.1 0.3
Comparative height size at age 10 0.1 0.6 2.0 -0.0 1.4 -0.5 -0.1 -0.3 0.2 -0.5 -1.4
Number of full sisters 0.3 0.4 1.9 -1.4 -0.3 -0.9 -0.2 -0.1 0.3 -0.4 0.5
Suffer from ‘nerves’ 1.4 2.3 5.0 -2.2 0.9 -0.9 -1.6 -1.8 -0.5 -2.0 -1.3
Overall health rating 0.4 0.9 2.5 0.3 0.5 -1.1 1.2 0.5 1.2 0.1 1.6
Chest pain or discomfort 0.3 0.5 1.7 0.4 0.7 -1.3 0.1 0.2 1.0 -0.4 0.6
Had major operations 0.3 0.4 1.2 0.4 0.6 -0.1 0.1 -1.1 -1.1 -0.4 -0.2
Age at last live birth 0.3 0.5 3.2 -1.8 -0.1 0.0 0.6 -0.2 0.5 0.2 0.1
Family relationship satisfaction 1.2 1.5 6.6 -0.5 2.6 -0.5 1.6 0.6 1.0 0.3 1.0
Leg pain on walking 0.8 1.1 2.5 -0.8 1.2 -1.1 0.9 0.9 1.6 -0.5 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.7 0.3 0.4 0.3 0.3 -0.8 0.8 -0.2 -0.5
Commuting to job workplace: Car/motor vehicle 1.4 1.6 5.4 -1.3 0.6 -2.3 -1.0 -1.2 -0.5 -1.1 -1.1
Illness, injury, bereavement, stress in last 2 years 1.5 1.8 4.0 -0.7 -1.2 -0.1 -1.8 -0.8 -1.3 -2.0 -1.7
Medication: Aspirin 0.9 1.1 4.2 -0.4 -0.3 -2.0 -0.2 -1.1 -0.0 -1.5 -0.9
Supplements: Vitamin C 0.6 0.7 1.4 -0.1 0.6 -0.7 1.0 1.1 0.5 1.2 0.7
Knee pain experienced in last month 0.7 1.1 2.9 0.1 -0.4 -1.3 -1.4 0.0 -0.8 -1.7 -1.3
Hypertension (Self-reported) 0.5 1.3 3.4 -1.6 -1.9 -0.3 0.6 -0.2 1.1 -1.5 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.1 -0.2 -0.9 1.0 1.4 1.0 0.7 0.3 -1.1
Illnesses of father: Heart disease 0.5 0.6 1.4 0.4 0.5 -0.5 1.1 1.2 1.1 0.5 0.4
Illnesses of siblings: Diabetes 0.3 0.4 0.9 -0.5 -0.4 -0.7 -0.6 0.9 0.4 0.1 0.9
Smoking status: Previous 5.2 7.8 12.7 3.1 -2.2 2.9 3.0 2.0 2.3 3.6 2.9
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.1 0.3 -0.4 0.4 0.2 0.5 0.2 0.4 -0.2 0.1
Whole body fat-free mass 0.2 1.4 6.1 -0.3 1.3 -0.5 2.5 0.7 1.5 0.6 -0.0
Leg fat-free mass (right) 0.3 1.6 5.5 -0.7 1.6 -0.9 2.3 0.7 1.6 0.2 0.1
Arm fat percentage (left) 0.3 1.0 2.6 -0.8 0.6 -0.7 1.1 1.6 1.1 -1.0 1.0
Average weekly red wine intake 0.1 0.2 0.6 0.8 -0.0 -0.2 -0.6 -0.3 -0.5 -0.2 -0.6
Handedness (chirality/laterality): Left-handed 0.8 1.0 2.8 -0.3 -1.7 0.1 -1.3 -1.0 -1.3 -0.8 -0.2
Mood swings 0.7 1.3 4.5 -0.3 0.3 -0.1 1.7 1.2 2.1 0.8 1.0
Loneliness, isolation 2.0 2.7 8.6 -2.6 2.9 -1.8 -1.3 -0.3 -0.6 -1.0 -0.5
Long-standing illness, disability or infirmity 0.4 0.6 1.7 0.0 0.3 -1.1 -0.4 -1.1 -0.2 -1.3 -0.3
Ever had bowel cancer screening 0.3 0.3 1.0 0.8 -0.4 0.7 -0.3 -0.0 -0.4 1.0 -0.1
Diabetes diagnosed by doctor 0.3 0.5 1.8 -0.2 -0.8 -1.1 0.2 0.1 0.3 -1.3 0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 2.5 0.1 -0.5 1.6 0.9 -0.3 0.4 0.8 1.3
Friendships satisfaction 1.0 1.3 3.9 -0.7 2.0 -1.3 -0.7 -1.1 -1.0 -1.2 -0.2
Qualifications: nursing, teaching 0.3 0.4 2.1 1.5 0.5 0.7 -0.0 -0.2 -0.6 0.2 -0.4
Commuting to job workplace: Walk 0.5 0.6 1.7 -0.7 -0.5 0.5 -0.6 -1.3 -0.7 -0.4 -0.9
Eye problems/disorders: Cataract 0.7 0.8 1.4 1.2 -0.4 0.6 1.1 0.5 0.8 0.9 1.1
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.8 1.7 0.2 0.0 -0.1 0.5 0.2 0.1 -0.7
Medication for cholesterol 0.3 0.4 1.5 -0.1 1.2 0.2 -0.5 -0.1 -0.5 1.0 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.9 0.4 -0.1 0.5 -0.1 -0.2 -0.4 0.2 1.0
Back pain experienced in last month 0.8 1.2 3.4 0.0 -1.3 -0.6 -1.1 -1.8 -0.7 -1.1 -1.0
Mineral and other dietary supplements 0.4 0.5 1.6 0.9 1.3 0.5 0.8 0.7 0.6 0.3 0.0
Breast cancer (self-reported) 1.5 1.8 5.1 1.4 -0.6 2.2 1.5 -0.2 0.3 2.1 0.6
Asthma (self-reported) 2.5 4.9 11.5 1.1 -0.5 2.1 3.4 1.4 2.1 3.0 2.6
Osteoporosis (self-reported) 0.1 0.1 0.3 0.1 -0.5 -0.2 -0.3 0.1 -0.3 -0.3 0.0
Osteoarthritis (self-reported) 0.1 0.1 0.2 -0.0 0.4 0.1 -0.2 0.4 -0.1 0.0 -0.4
Medication: Aspirin 0.6 0.8 3.5 -0.1 -0.2 -1.9 0.4 -0.6 0.5 -1.5 -0.4
Medication: Gliclazide 0.7 0.8 3.9 -2.0 0.7 -0.9 -0.3 -0.7 -0.2 -0.8 0.5
Illnesses of father: None of the above (group 1) 1.1 1.4 3.9 -1.7 0.0 0.1 -0.6 -2.0 -0.9 -0.8 -1.6
Smoking status: Current 0.8 1.3 6.1 -0.8 2.5 -0.1 1.5 0.2 -0.3 0.9 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.8 4.4 -1.5 1.6 -2.1 -1.1 -0.9 -1.4 -1.1 -0.4
Whole body water mass 0.2 1.3 5.4 -0.3 1.4 -0.7 2.3 0.8 1.4 0.5 -0.0
Leg predicted mass (right) 0.3 1.6 5.7 -0.8 1.6 -0.8 2.4 0.8 1.6 0.3 0.1
Arm fat mass (left) 0.3 1.3 2.9 -0.6 1.2 -0.7 1.6 1.7 1.2 -0.4 1.0
Number of self-reported non-cancer illnesses 1.2 2.1 7.0 0.6 -1.6 0.4 2.6 1.3 1.3 1.0 1.5
Average weekly champagne plus white wine intake 0.3 0.5 2.2 -1.5 -0.3 -0.1 -0.0 -0.1 -1.0 0.4 -0.3
Miserableness 0.4 0.7 1.9 -0.8 0.3 -1.4 -0.6 -0.3 0.7 -1.1 -0.9
Guilty feelings 0.4 0.6 1.6 0.4 -0.4 -1.1 -0.9 0.4 -0.3 -0.9 -1.2
Wears glasses or contact lenses 0.3 0.3 1.0 1.0 0.0 -0.4 -0.4 -0.1 -0.6 -0.2 -0.8
Ever taken oral contraceptive pill 0.6 0.7 2.4 -0.4 -0.2 0.0 0.7 0.7 1.3 0.2 1.6
Hearing aid user 0.4 0.4 1.2 0.3 0.0 -0.9 -1.1 -0.3 -0.3 -1.0 -0.0
Mother’s age at death 0.7 0.8 2.1 0.1 -0.0 -1.2 -1.0 -1.4 -0.4 -0.9 -1.0
Financial situation satisfaction 0.7 0.8 3.2 0.4 1.8 0.1 0.7 -0.5 -0.2 0.9 1.2
Tinnitus: Yes, now most or all of the time 1.1 1.2 6.1 2.5 0.9 0.7 -1.1 -0.1 -0.8 0.8 0.5
Commuting to job workplace: Public transport 0.5 0.6 1.5 0.3 -1.0 1.2 0.6 0.7 1.1 0.1 0.7
Eye problems/disorders: Glaucoma 0.3 0.3 0.7 0.2 0.9 -0.6 -0.7 0.2 0.1 -0.8 -0.6
Medication: Blood pressure 0.4 0.8 3.9 -0.7 -2.0 0.3 0.7 0.7 0.8 -0.5 0.5
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.3 -0.0 -0.5 0.0
Supplements: Fish oil (including cod liver oil) 0.3 0.3 0.9 -1.0 -0.4 -0.8 -0.5 -0.7 -0.2 -0.2 0.2
High cholesterol (Self-reported) 0.4 0.7 2.5 0.3 -1.6 1.1 1.0 0.3 0.7 0.1 0.7
Medication: Bendroflumethiazide 0.9 1.4 4.5 0.9 0.2 0.9 1.3 2.1 1.1 1.0 1.0
Medication: Paracetamol 0.3 0.5 1.2 -0.8 0.5 -1.1 0.1 0.2 1.0 -0.7 0.9
Medication: Lisinopril 1.7 2.2 6.6 0.5 -0.5 0.8 1.5 2.6 1.9 1.2 1.5
Medication: Atorvastatin 0.3 0.4 1.5 0.2 -1.2 1.2 -0.3 0.4 -0.2 0.3 0.4
Illnesses of father: High blood pressure 0.4 0.5 1.7 -0.0 -0.3 -1.3 -0.3 -0.9 0.4 -0.8 0.5
Alcohol drinker status: Never 2.6 3.1 6.6 -1.7 0.2 -1.9 -1.8 -2.0 -1.5 -2.6 -1.4
Ever smoked 4.5 8.0 13.5 1.4 0.6 2.1 3.7 3.3 3.1 3.6 3.1
Basal metabolic rate 0.3 1.4 5.5 -0.4 1.5 -0.5 2.3 0.9 1.4 0.4 0.2
Leg fat percentage (left) 0.5 1.9 6.7 -0.6 0.7 0.0 1.6 2.6 1.7 -0.2 1.5
Arm fat-free mass (left) 0.2 1.3 4.3 -0.4 1.6 -0.6 2.1 0.9 1.3 0.5 0.2
Number of operations (self-reported) 0.7 1.1 2.0 1.4 -1.2 -0.2 1.4 1.4 0.4 0.7 0.9
Average weekly beer plus cider intake 0.3 0.5 2.4 0.5 -1.6 0.8 -0.1 -0.0 -0.2 0.1 0.6
Irritability 0.5 0.9 2.9 -0.3 1.7 -0.5 1.0 0.2 1.7 -0.5 -0.1
Risk taking 0.5 0.7 2.3 0.6 0.9 0.1 1.1 0.8 1.5 0.5 0.3
Ever had prostate specific antigen (PSA) test 1.6 1.8 4.2 0.7 0.8 -0.5 -1.6 -1.5 -2.1 -0.8 -1.9
Fractured/broken bones in last 5 years 1.3 1.6 11.4 0.2 -3.4 0.3 -0.0 1.1 0.1 0.3 -0.1
Age started oral contraceptive pill 0.9 1.1 2.1 -0.6 -0.6 -1.1 -0.8 -1.2 -1.2 -1.4 -1.1
Diastolic blood pressure, automated reading 0.1 0.4 1.2 -0.1 -0.6 -0.8 0.3 -0.1 0.8 -1.1 -0.8
Ever depressed for a whole week 1.5 1.8 4.8 1.5 1.8 -1.1 0.7 2.2 1.6 -0.0 0.4
Unable to work because of sickness or disability 0.3 0.4 1.6 0.3 0.5 0.3 0.2 0.0 0.3 1.1 1.3
Commuting to job workplace: Cycle 1.3 1.6 3.4 0.0 -1.5 -0.1 -0.8 -1.8 -1.9 -1.0 -1.5
Myopia 0.8 1.1 3.6 -0.8 1.0 -0.8 -1.1 -1.1 -1.9 -0.4 -0.7
Vascular/heart problems diagnosed by doctor 0.4 1.2 3.6 1.3 1.5 1.1 0.0 0.6 -0.7 1.9 0.6
Cholesterol lowering medication 0.2 0.3 0.9 -0.2 -0.9 0.5 0.4 0.1 0.7 -0.8 0.1
Medication: Omeprazole (e.g. Zanprol) 1.6 2.0 4.5 -1.9 -1.5 -0.8 -0.4 -0.7 -0.5 -2.1 -1.9
Pain experienced in last month 0.3 0.4 1.2 -0.2 -0.1 1.0 -0.1 -1.1 -1.0 0.5 -0.4
Supplements: Calcium 0.6 0.7 2.3 0.3 -1.5 -1.0 -0.2 -0.7 -0.8 -0.4 -0.9
Basal cell carcinoma (self-reported) 0.9 1.1 2.8 -1.2 0.5 0.4 1.5 0.8 1.7 0.5 0.9
Heart attack/myocardial infarction (self-reported) 0.8 1.0 2.0 1.2 -1.4 -0.1 0.8 1.1 1.1 0.8 1.0
Deep venous thrombosis (DVT) (self-reported) 0.5 0.7 1.3 0.6 -0.6 0.3 1.1 0.6 1.1 0.9 0.9
Heart disease (siblings) 1.3 1.5 6.1 2.5 0.2 0.9 1.1 1.4 0.8 1.0 0.6
Alcohol drinker status: Previous 1.4 1.6 2.3 1.5 -1.2 1.4 1.0 1.5 0.9 1.2 1.4
Pack years of smoking 1.0 1.5 2.7 -1.3 1.3 -1.0 -0.9 -1.3 -1.0 -1.2 -1.7
Impedance of whole body 0.3 1.6 3.9 0.3 -1.5 1.8 -2.0 -0.7 -0.9 -0.9 -0.9
Leg fat mass (left) 0.6 2.3 6.4 -0.5 1.3 -0.2 2.1 2.5 1.9 0.0 1.3
Arm predicted mass (left) 0.2 1.3 4.4 -0.4 1.6 -0.5 2.1 1.0 1.2 0.5 0.2