Hub : Genes

CEP70

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.1520	0.0640	9.5e-05	0.035	NA	0.076	NA	0.044	2.1e-03	NA	8.4e-06	NA	6.5e-04
2	GTEx	Muscle Skeletal	0.0800	0.0324	1.2e-04	0.056	NA	0.057	NA	0.058	3.4e-06	NA	2.8e-06	NA	2.1e-06
3	GTEx	Testis	0.1880	0.0760	2.1e-04	0.042	NA	0.083	NA	0.088	5.9e-03	NA	1.6e-04	NA	1.0e-04
4	GTEx	Thyroid	0.1740	0.0560	7.9e-05	0.010	NA	0.038	NA	0.028	5.3e-02	NA	6.8e-04	NA	3.1e-03
5	YFS	Blood	0.0468	0.0140	2.3e-09	0.033	0.035	0.028	0.038	0.031	4.4e-11	1.4e-11	1.5e-09	1.9e-12	2.1e-10
6	TCGA	Brain Lower Grade Glioma	0.0345	0.0183	3.0e-04	0.025	0.023	0.024	NA	0.016	6.0e-04	1.1e-03	9.0e-04	NA	4.9e-03
7	TCGA	Prostate Adenocarcinoma	0.2332	0.0864	2.9e-06	0.038	0.046	0.037	NA	0.035	6.5e-05	1.4e-05	8.8e-05	NA	1.3e-04
8	TCGA	Thyroid Carcinoma	0.0390	0.0250	9.7e-03	0.004	0.020	0.011	NA	0.013	1.3e-01	4.5e-03	2.7e-02	NA	1.7e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.0	1.6	3.9	-1.8	-0.2	0.7	-0.6	-1.9	-0.1	-2.0	-0.9
Bipolar Disorder or Schizophrenia	0.5	1.2	3.2	-1.8	0.7	1.6	0.5	-0.8	0.9	-1.1	0.0
Depressed Affect (Nagel 2018)	2.8	6.0	13.8	-3.3	3.0	3.7	1.5	-0.7	2.6	-1.6	1.3
Depression (Nagel 2018)	0.5	0.7	1.8	-1.1	0.9	1.3	0.3	0.8	0.9	-0.3	0.6
Intelligence (Savage-Jansen 2018)	2.0	6.3	10.6	-2.1	3.0	2.4	3.0	0.6	3.3	1.4	3.0
Neuroticism (Nagel 2018)	1.6	3.8	8.0	-2.8	2.2	2.8	1.5	-0.7	2.0	-1.4	1.2
Schizophrenia (2018)	0.5	1.0	2.5	-0.9	1.1	1.6	1.1	0.5	1.3	0.2	0.7
Schizophrenia vs Biploar Disorder	1.4	1.9	3.3	1.3	-1.7	-1.0	-1.7	-0.1	-1.7	-0.5	-1.8
Worry (Nagel 2018)	0.3	0.7	2.2	-0.9	0.2	0.6	-0.3	-1.5	0.0	-1.3	-0.5
Alzheimer’s Disease (in mother)	1.7	1.9	3.8	-0.0	1.4	0.3	1.3	1.8	1.5	1.5	1.9
Alzheimer’s Disease (in father)	0.3	0.4	1.5	-0.4	0.6	0.7	0.2	-1.2	0.1	-0.5	-0.2
Alzheimer’s Disease (including proxy)	1.1	1.6	2.8	-0.5	1.7	1.1	1.5	0.5	1.5	1.0	1.6
Crohns Disease (2017)	0.7	1.5	4.9	-0.2	0.2	0.9	-1.3	-2.2	-0.5	-1.7	-1.3
Irritable Bowel Disease (IBD)	0.5	1.1	4.0	0.2	0.1	0.3	-1.1	-2.0	-0.8	-0.8	-1.4
Ulcerative Colitis (UC)	0.2	0.3	0.9	0.2	0.1	-0.1	-0.4	-1.0	-0.5	0.5	-0.8
Major Depression (MDD)	0.1	0.2	0.4	-0.0	0.2	0.6	0.5	0.5	0.4	-0.2	0.4
Reaction Time	0.3	0.5	1.6	0.7	-0.5	-1.3	-0.8	0.9	-0.5	-0.0	0.2
Verbal and Numeric Reasoning (VNR)	2.5	5.9	9.5	-3.1	2.5	3.1	2.6	-0.2	2.9	-1.0	2.5
Breast Cancer	1.2	3.0	7.5	-1.7	2.0	2.7	1.3	-1.2	1.6	-1.8	0.5
Ovarian Cancer	1.4	1.8	4.8	2.2	-1.3	-2.0	-0.6	-0.0	-1.6	0.3	-1.1
Prostate Cancer	0.1	0.2	0.9	0.9	-0.2	0.2	0.1	0.0	-0.1	-0.6	-0.2
Age at First Birth	1.7	2.5	5.4	2.3	-1.4	-2.3	-0.1	2.0	-1.4	1.2	0.2
Bipolar Disorder (2011)	0.9	0.8	2.5	-1.5	0.4	1.1	-0.4	-1.6	0.3	-0.4	-0.4
Body Mass Index (BMI) (2010)	2.4	3.2	5.6	-1.9	2.2	2.4	2.0	0.6	2.2	-0.6	1.4
Coronary Artery Disease (CAD)	2.8	3.3	5.4	-0.3	2.1	1.0	2.1	1.7	2.2	1.9	2.3
Crohns Disease (2012)	1.3	2.1	4.4	-1.4	0.1	1.4	-1.3	-2.1	-0.3	-2.0	-1.4
Mean Putamen Volume	0.9	1.1	2.8	1.1	-1.1	-1.7	-0.9	0.2	-1.0	1.1	-0.6
Fasting Glucose	1.2	1.4	3.5	-0.2	1.5	0.6	1.9	1.0	1.4	0.7	1.2
HbA1C	1.0	1.1	2.6	-1.5	0.7	0.4	1.0	0.9	1.1	0.1	1.6
HDL Cholesterol	0.2	0.4	1.1	0.4	-0.8	-1.1	0.1	0.6	-0.3	0.7	0.1
LDL Cholesterol	1.2	1.9	5.2	-1.9	1.4	2.3	0.8	-0.7	1.4	-0.7	0.9
Lupus	0.6	1.0	3.8	0.9	-0.4	-0.7	0.5	2.0	0.1	1.2	0.9
Neuroticism (2016)	0.9	1.4	3.7	0.4	1.5	0.4	1.3	0.6	1.2	1.1	1.9
Primary Biliary Cirrhosis	2.9	4.1	6.9	-1.8	2.2	1.7	2.5	1.4	2.5	0.7	2.6
Rheumatoid Arthritis	0.9	1.2	2.0	1.3	-1.2	-0.3	-1.4	-0.5	-1.2	-1.2	-1.2
Schizophrenia (2014)	0.1	0.2	0.9	-0.5	0.2	1.0	0.0	0.1	0.4	-0.2	-0.2
Triglycerides	0.4	0.6	1.4	-0.7	0.7	1.2	-0.1	-1.1	0.4	-1.2	-0.1
Type 2 Diabetes (T2D) (2012)	1.9	2.1	4.7	-1.7	1.8	2.2	1.4	-0.1	1.8	0.0	1.0
Ulcerative Colitis	0.3	0.4	1.0	0.6	0.0	-0.1	-0.4	-1.0	-0.8	-0.4	-1.0
Blood Eosinophil Count	0.7	5.2	17.4	4.2	-1.9	-3.1	-2.0	1.5	-2.2	0.2	-0.4
Blood Platelet Count	1.0	11.3	25.4	4.9	-3.6	-5.0	-1.8	3.6	-3.2	1.3	-0.1
Blood Red Count	0.0	0.2	0.6	0.4	0.1	-0.5	-0.3	0.8	-0.1	-0.2	-0.0
Blood White Count	0.2	1.3	2.8	-0.5	1.4	0.8	1.7	0.5	1.4	-0.1	1.6
Heel T-Score	1.3	10.6	17.1	3.8	-4.0	-4.1	-3.7	0.1	-4.1	-0.4	-2.6
BMI	0.2	1.0	2.9	-0.2	1.7	1.4	0.8	0.2	1.0	-0.9	0.7
Height	0.7	14.1	23.4	3.9	-4.8	-4.7	-3.9	-0.1	-4.7	1.5	-3.6
Waist Hip Ratio (WHR)	3.5	15.8	26.6	-3.6	4.9	4.8	4.3	1.2	5.2	1.5	4.2
Systolic Blood Pressure	0.4	1.8	3.8	-1.8	1.7	2.0	0.9	-0.4	1.6	-0.1	0.8
Smoking Status	0.7	1.7	3.1	1.5	-0.8	-0.7	-1.5	-1.4	-1.6	-0.7	-1.8
Allergy or Eczema	0.0	0.1	0.1	0.1	-0.2	-0.1	0.4	0.3	0.2	-0.2	0.4
Cardiovascular Disease	3.4	11.4	18.8	-1.8	4.3	3.6	4.3	1.3	4.3	0.6	4.1
Hypothyroidism (self reported)	0.6	1.3	4.0	1.5	0.6	-0.5	1.2	1.0	0.6	2.0	1.1
Respiratory disease	0.8	1.7	5.0	-1.5	1.7	2.2	0.8	-0.3	1.4	-0.8	0.6
Type 2 Diabetes (T2D) (2018)	4.5	8.4	14.5	-2.5	3.6	2.9	3.4	1.4	3.8	0.6	3.4
Lung FEV1/FVC ratio	0.0	0.1	0.5	-0.4	0.3	-0.0	0.2	0.7	0.3	0.3	0.4
Lung FVC	2.4	12.4	22.0	4.7	-4.1	-4.7	-3.3	0.7	-4.1	1.4	-2.9
Neuroticism	1.3	3.0	7.5	-2.6	1.4	2.7	0.4	-1.8	1.2	-1.8	0.2
Chronotype (morning person)	2.4	5.5	12.7	2.5	-2.9	-3.6	-2.1	1.4	-2.6	1.2	-1.3
Hair Pigment	0.2	4.6	10.4	-3.2	2.3	2.9	1.7	-0.5	2.3	-1.7	1.2
Tanning	0.1	1.4	2.6	0.4	-1.6	-1.2	-1.5	0.1	-1.5	0.7	-1.4
Hand grip strength (left)	0.7	2.0	4.0	1.4	-2.0	-1.4	-1.5	-0.5	-1.7	-0.1	-1.5
Number of treatments/medications taken	7.9	14.2	23.6	-3.5	4.6	4.1	4.2	1.8	4.9	0.6	4.2
Average weekly spirits intake	0.5	0.6	1.7	-1.0	0.4	0.3	1.0	0.8	0.7	-0.5	1.3
Sensitivity / hurt feelings	0.1	0.1	0.2	-0.2	0.3	0.3	0.5	0.5	0.2	-0.5	0.2
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.8	-0.9	-0.1	0.6	-0.0	0.4	0.2	0.1	0.1
Hearing difficulty/problems: Yes	1.4	2.2	4.7	-1.6	2.2	1.8	1.6	0.1	1.9	-0.3	0.9
Relative age of first facial hair	0.2	0.5	1.1	-0.7	-0.4	0.8	-0.4	-0.9	-0.3	-1.0	-0.6
Other serious medical condition/disability diagnosed by doctor	4.7	6.1	11.1	-1.5	3.3	1.7	2.9	1.7	3.2	1.2	3.0
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.1	0.8	-1.2	-1.7	-0.1	2.0	-0.3	1.3	0.8
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	0.5	0.3	-0.2	0.3	-0.1	0.2	0.6	0.1
Systolic blood pressure, automated reading	0.6	1.6	3.8	-1.4	2.0	1.7	0.8	-0.5	1.6	0.2	0.8
Eye problems/disorders: Diabetes related eye disease	3.8	4.2	7.1	-2.0	1.9	1.1	2.4	2.2	2.5	0.9	2.7
Angina	3.3	4.4	9.8	-0.9	3.1	2.4	2.6	0.3	2.6	0.3	2.2
Medication for hormone replacement therapy	0.5	0.5	1.0	0.6	-1.0	-0.5	-0.9	0.2	-0.9	0.6	-0.8
Vitamin and mineral supplements	1.7	2.3	6.1	-0.7	2.0	2.5	0.9	-2.3	1.1	-0.9	-0.3
Supplements: Zinc	0.5	0.6	3.3	-1.8	0.2	0.3	0.2	-0.4	0.7	0.3	0.7
Medication: Co-codamol	3.5	4.1	7.8	-0.4	2.5	1.5	2.8	1.6	2.5	0.5	2.8
Medication: Metformin	1.3	1.8	2.9	-1.7	1.6	1.4	1.3	0.2	1.6	-0.6	1.4
Diabetes (father)	0.2	0.2	1.4	0.4	-0.3	-0.2	-0.2	1.2	-0.4	-0.2	-0.0
Diabetes (mother)	0.6	0.7	2.1	-1.4	0.5	1.0	1.0	-0.0	0.9	-0.3	0.8
Severe depression (siblings)	0.1	0.2	0.9	-0.9	-0.0	-0.0	-0.3	0.3	0.1	0.3	0.2
Pack years adult smoking proportion	1.1	1.7	3.1	-1.7	1.8	1.7	1.0	-0.2	1.6	-0.5	1.0
Impedance of leg (right)	0.2	0.9	3.1	0.6	-1.1	-0.9	0.1	1.8	-0.4	0.8	0.6
Leg fat-free mass (left)	0.4	2.1	4.0	1.2	-1.3	-1.2	-1.8	-1.3	-1.8	-0.3	-2.0
Trunk fat percentage	0.0	0.2	0.5	0.7	0.4	0.3	-0.1	0.0	-0.1	-0.6	-0.4
Hand grip strength (right)	1.6	4.4	8.5	1.9	-2.9	-2.1	-2.0	-0.7	-2.8	-1.3	-2.1
Townsend deprivation index at recruitment	0.2	0.3	1.7	1.3	0.4	-0.6	0.2	0.2	-0.3	0.4	0.1
Current tobacco smoking	2.0	3.2	5.2	1.8	-1.4	-1.2	-1.9	-1.4	-2.3	-1.8	-2.1
Average weekly fortified wine intake	0.4	0.5	1.2	0.5	-0.6	-0.3	-1.1	-0.7	-0.7	-0.4	-0.7
Maternal smoking around birth	1.1	1.6	5.5	0.9	-0.3	-1.3	1.1	1.3	0.3	2.4	1.2
Fed-up feelings	1.9	3.4	8.7	-2.2	2.3	2.9	0.5	-1.6	1.3	-2.0	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.9	0.4	-0.5	-0.3	-1.0	0.2	-0.8	-0.3	-0.8
Relative age voice broke	0.9	1.3	4.6	-1.4	0.9	2.1	0.9	-0.6	0.9	-1.2	0.2
Taking other prescription medications	7.6	11.7	20.6	-3.0	4.3	3.6	3.9	1.0	4.5	1.1	3.9
Age when periods started (menarche)	2.7	6.4	10.0	2.2	-2.9	-2.8	-2.9	-1.5	-3.2	0.9	-2.9
Bilateral oophorectomy (both ovaries removed)	3.3	3.8	10.5	3.2	-0.8	-2.4	0.1	2.2	-0.6	2.7	0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	5.2	2.3	-1.5	-1.7	-1.4	-0.2	-1.9	-0.3	-1.6
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	2.5	1.0	-1.4	-0.6	-1.3	0.0	-1.6	-1.2	-1.4
Qualifications: CSEs or equivalent	0.7	0.9	1.5	0.4	-0.8	-0.3	-1.2	-0.9	-1.2	-1.1	-1.1
Serious illness, injury or assault to yourself	2.6	3.2	5.6	0.0	2.1	1.0	2.1	1.8	2.0	1.8	2.4
High blood pressure	4.5	12.5	21.7	-3.0	4.7	3.9	4.2	1.1	4.6	0.8	3.7
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.6	0.1	-0.8	0.1	-0.2	-0.2	-0.3	-0.5	-0.4
Multivitamins +/- minerals	3.0	3.8	11.4	1.6	-2.6	-3.4	-1.2	2.1	-1.6	1.3	0.1
Stomach or abdominal pain in last month	0.5	0.7	1.9	-0.8	0.4	1.0	0.2	-1.3	0.3	-1.4	0.0
Supplements: Glucosamine	0.1	0.1	0.2	0.3	-0.3	-0.1	-0.1	0.5	-0.0	0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	-0.4	0.7	0.4	1.1	0.5	0.8	-0.2	1.1
Medication: Atenolol	2.8	3.5	7.1	-0.8	2.7	1.8	2.4	0.6	2.2	0.4	2.3
Medication: Levothyroxine sodium	0.2	0.4	1.0	0.4	0.6	0.1	1.0	0.5	0.6	0.8	0.4
Sitting height	1.2	8.8	19.3	3.1	-4.0	-4.4	-2.7	1.0	-3.5	1.1	-1.9
Chronic bronchitis/emphysema (father)	0.7	0.8	2.1	0.2	0.6	0.2	0.9	1.4	0.8	0.7	1.3
High blood pressure (mother)	3.9	5.4	10.7	-1.2	2.4	1.4	3.2	2.1	2.8	0.5	3.3
Body mass index (BMI)	0.3	1.3	3.8	-0.2	2.0	1.9	0.6	-0.6	1.0	-1.2	-0.0
Impedance of leg (left)	0.1	0.5	1.2	0.5	-1.1	-0.8	-0.0	1.1	-0.4	0.5	0.4
Leg predicted mass (left)	0.4	2.1	4.1	1.3	-1.2	-1.2	-1.8	-1.3	-1.8	-0.3	-2.0
Trunk fat mass	0.1	0.3	0.9	0.9	0.1	0.0	-0.5	-0.2	-0.5	-0.6	-0.8
Waist circumference	0.9	3.4	8.3	-1.3	2.9	2.7	1.7	-0.0	2.3	-0.4	1.2
Number of incorrect matches in round	1.1	1.9	4.0	1.5	-1.7	-2.0	-1.3	1.1	-1.5	0.9	-0.4
Past tobacco smoking	1.7	3.2	4.9	-1.9	1.7	1.8	2.2	1.0	2.2	-0.4	2.2
Alcohol usually taken with meals	3.6	5.8	13.6	2.6	-3.0	-3.7	-1.2	2.6	-2.1	2.0	-0.5
Nervous feelings	0.2	0.3	0.8	-0.6	0.7	0.6	0.1	-0.9	0.4	-0.3	-0.1
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	4.8	0.2	-0.8	-0.2	-2.0	-2.2	-1.5	-0.4	-2.1
Hearing difficulty/problems with background noise	0.6	1.0	2.5	-1.5	1.1	1.3	0.4	-0.1	0.9	-1.6	-0.1
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	0.5	-0.5	0.0	-0.2	-0.1	-0.3	0.6	-0.3
Had menopause	0.2	0.3	0.7	0.7	-0.5	-0.7	-0.3	0.8	-0.3	0.6	0.1
Had other major operations	0.9	1.1	1.7	-0.5	1.0	0.2	1.1	1.3	1.3	1.2	1.2
Forced vital capacity (FVC)	2.5	9.7	23.0	3.3	-4.4	-4.8	-2.5	1.1	-3.6	1.3	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	3.0	6.9	12.0	3.2	-2.9	-2.3	-2.9	-0.5	-3.5	-1.2	-3.0
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.0	-0.4	1.4	1.7	0.7	0.1	0.8	-1.4	0.2
Qualifications: None of the above	0.5	1.0	3.1	-0.1	-0.1	-0.2	-1.3	-1.8	-0.7	-0.6	-1.6
Financial difficulties in last 2 years	0.4	0.5	1.1	0.5	-0.7	-0.1	-1.1	-0.4	-0.8	-0.7	-1.0
Mouth/teeth dental problems	0.3	0.5	1.3	0.6	-1.0	-0.5	-1.1	-0.3	-0.8	-0.1	-0.8
Heart attack	3.5	4.5	9.1	-1.2	3.0	2.0	2.6	0.6	2.7	0.5	2.5
Allergy	0.2	0.5	1.1	0.6	-0.4	-1.1	-0.9	-0.6	-0.9	-0.2	-0.7
Pain all over the body in last month	0.1	0.1	0.5	-0.5	0.2	0.2	-0.1	-0.7	-0.1	0.1	-0.3
Diabetes (self-reported)	1.7	2.6	4.7	-1.6	1.9	1.3	1.6	0.8	2.1	0.4	2.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.7	-0.2	0.0	-0.0	1.3	0.9	0.7	0.6	0.9
Medication: Ramipril	5.5	7.0	12.2	-2.7	3.5	3.5	2.7	-0.3	3.2	-1.4	2.2
Medication: Simvastatin	4.0	5.9	12.1	-1.8	3.5	3.2	2.6	-0.0	3.1	0.3	2.2
Fluid intelligence score	2.3	4.8	10.1	-2.6	2.6	3.2	2.1	-0.6	2.5	-1.2	1.8
Illnesses of siblings	2.2	3.1	5.8	1.4	-2.4	-2.0	-2.2	-0.4	-2.1	-0.6	-1.8
Neuroticism score	0.5	1.1	2.5	-1.3	0.9	1.6	-0.1	-1.6	0.4	-1.1	-0.4
Weight	0.1	0.6	1.5	1.2	-0.3	-0.4	-0.8	-0.3	-0.9	-0.5	-1.1
Impedance of arm (right)	0.1	0.7	1.5	0.1	-1.2	-0.9	0.0	1.2	-0.3	1.1	0.3
Arm fat percentage (right)	0.1	0.5	1.2	0.5	1.1	1.1	0.1	-0.3	0.3	-0.8	-0.3
Trunk fat-free mass	0.7	3.8	6.6	1.7	-1.8	-1.6	-2.4	-1.7	-2.4	-0.7	-2.6
Hip circumference	0.1	0.4	1.4	0.1	0.4	0.6	-0.3	-0.6	-0.1	-1.2	-0.8
Time employed in main current job	0.2	0.3	1.1	-0.6	-0.0	0.6	0.1	-0.5	0.2	-1.0	0.1
Alcohol intake versus 10 years previously	0.5	0.8	2.0	-0.6	1.4	1.0	0.7	0.8	1.1	-0.0	0.9
Father’s age at death	5.4	7.3	14.9	2.6	-3.9	-3.5	-2.7	1.7	-3.2	0.7	-1.8
Worrier / anxious feelings	0.3	0.5	2.0	-1.4	0.3	0.9	0.4	-0.3	0.6	-0.7	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.7	0.4	0.5	-0.6	0.9	1.1	0.6	1.6	1.1
Falls in the last year	0.3	0.4	0.9	-1.0	0.4	0.7	0.7	0.4	0.6	-0.3	0.5
Hair/balding pattern: Pattern 3	0.3	0.4	1.7	0.1	0.3	-0.8	0.5	1.3	0.2	-0.0	0.7
Number of live births	1.1	1.6	3.1	-0.4	1.8	1.4	1.8	0.6	1.5	0.1	1.4
Forced expiratory volume in 1-second (FEV1)	2.2	7.4	18.1	2.8	-3.8	-4.2	-2.3	1.3	-3.0	1.2	-1.3
Pulse rate	1.2	2.0	5.1	-1.7	1.7	2.3	0.8	-1.2	1.3	-1.0	0.2
Happiness	0.1	0.1	0.4	0.4	0.3	-0.1	0.1	0.6	0.4	0.4	0.6
Noisy workplace	1.4	1.8	5.2	2.3	-0.9	-1.1	-1.6	0.6	-1.5	0.2	-1.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.7	-0.1	-0.2	0.1	0.3	0.0	0.4	0.9	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.5	-0.4	0.7	0.6	-0.2	-1.1	0.1	-1.6	-0.7
Mouth/teeth dental problems: Dentures	1.7	2.9	5.8	-0.9	2.4	1.7	2.3	0.0	2.1	-0.3	1.9
Asthma	0.6	1.3	2.4	-0.6	0.9	1.0	1.3	1.5	1.3	1.0	1.2
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	4.5	1.0	-2.1	-1.5	-2.0	-0.9	-2.1	-1.0	-1.8
Medication: Cholesterol lowering	4.9	7.6	15.2	-2.2	3.9	3.6	3.1	-0.2	3.5	0.7	2.4
Depression (self-reported)	2.6	3.1	5.3	-1.2	1.8	1.4	2.3	1.8	2.1	0.5	2.2
Medication: Lansoprazole	0.7	0.8	3.1	-1.8	0.6	0.8	0.1	-0.7	0.4	-1.3	0.3
Prospective memory result	1.7	2.2	5.0	-2.2	1.3	2.1	-0.1	-1.3	1.1	-1.7	-0.3
Lung cancer (father)	0.3	0.4	1.0	-0.1	-1.0	-0.3	-0.5	-0.0	-0.9	-0.4	-0.8
Illnesses of mother	6.6	8.1	13.5	2.8	-3.5	-3.1	-3.3	-0.8	-3.7	-0.4	-3.2
Forced expiratory volume in 1-second (FEV1), Best measure	3.1	9.9	19.2	3.1	-4.3	-4.4	-3.3	0.4	-3.9	0.6	-2.4
Pulse wave Arterial Stiffness index	0.7	0.9	2.8	1.7	-0.9	-1.1	-0.5	1.2	-0.6	0.3	-0.1
Impedance of arm (left)	0.2	0.9	2.6	-0.1	-1.6	-1.1	0.1	1.5	-0.5	0.7	0.6
Arm fat mass (right)	0.1	0.6	1.3	0.7	0.7	0.7	-0.5	-0.9	-0.3	-1.1	-0.9
Trunk predicted mass	0.7	3.9	6.7	1.7	-1.8	-1.6	-2.4	-1.7	-2.4	-0.7	-2.6
Standing height	1.1	11.2	23.7	3.1	-4.8	-4.9	-2.9	0.7	-4.0	1.5	-2.3
Length of working week for main job	0.7	0.8	1.6	-0.8	-0.6	0.0	-1.1	-1.1	-0.6	-1.3	-0.9
Exposure to tobacco smoke at home	1.1	1.3	2.2	1.3	-1.2	-1.0	-1.4	-0.6	-1.5	-0.1	-1.2
Breastfed as a baby	0.4	0.5	0.9	-0.8	0.9	0.9	0.5	-0.5	0.9	-0.3	0.4
Tense / ‘highly strung’	0.5	0.8	3.1	-1.0	0.3	0.7	-0.5	-1.8	0.1	-1.0	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.7	1.3	-0.1	-0.3	0.4	0.7	0.0	0.7	0.5
Hair/balding pattern: Pattern 4	1.2	2.8	10.5	1.9	-3.2	-1.7	-0.8	0.1	-1.3	1.7	-0.5
Birth weight of first child	0.2	0.4	1.0	-0.2	0.5	-0.4	0.7	0.7	0.6	0.8	1.0
Peak expiratory flow (PEF)	1.9	4.5	12.4	2.3	-2.5	-3.5	-0.7	2.4	-1.5	1.9	0.5
Pulse wave reflection index	0.5	0.6	1.8	1.3	-1.0	-0.6	-0.7	0.2	-0.8	-0.0	-0.5
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.5	-0.6	0.1	0.4	-0.3	-0.2	-0.0	-0.7	-0.2
Loud music exposure frequency	0.7	0.8	1.9	1.4	-0.2	-1.2	0.2	0.7	-0.3	1.2	0.9
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	3.3	-0.6	1.2	1.2	1.8	0.6	1.6	1.3	1.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	2.7	0.8	-1.6	-1.6	-1.4	0.0	-1.6	0.4	-1.1
Blood clot in the leg (DVT)	2.2	2.9	7.1	-1.7	2.5	2.7	1.2	-0.9	2.0	0.3	0.9
Medication: Paracetamol	0.5	0.7	3.0	0.2	-0.5	-1.0	-0.3	1.7	-0.0	1.0	0.7
Headache pain in last month	0.1	0.1	0.3	-0.3	-0.0	0.5	0.3	0.2	0.2	-0.6	0.3
Medication for cholesterol, blood pressure or diabetes	4.5	7.4	13.1	2.6	-3.6	-3.3	-3.1	-0.0	-3.5	-1.1	-2.5
Glaucoma (self-reported)	1.7	2.0	6.4	-0.2	-0.4	0.8	-1.4	-1.2	-1.2	-2.5	-1.9
Gout (self-reported)	2.0	2.7	5.1	-1.5	2.3	1.6	2.0	0.3	2.2	0.2	1.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	2.5	1.4	-0.1	-0.8	0.6	0.5	0.0	1.6	0.3
Medication: Amlodipine	0.5	0.7	2.4	0.1	0.9	0.4	1.0	-0.1	0.7	1.5	0.7
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.8	0.1	1.3	1.0	1.0	0.7	1.1	0.2	0.9
Birth weight	2.1	4.5	9.7	-1.6	2.4	2.0	3.1	0.9	2.7	0.7	2.4
Chronic bronchitis/emphysema (mother)	2.1	2.4	5.5	-2.4	0.7	1.6	-0.7	-2.4	0.3	-2.1	-0.6
High blood pressure (siblings)	1.2	1.7	3.1	-1.2	1.4	1.2	1.8	1.0	1.5	0.4	1.6
Forced vital capacity (FVC), Best measure	3.5	13.0	23.7	3.7	-4.9	-4.9	-3.7	0.1	-4.5	0.8	-2.9
Body fat percentage	0.1	0.4	1.2	0.5	1.1	1.0	0.4	0.3	0.5	-0.7	0.1
Leg fat percentage (right)	0.4	1.6	4.0	0.5	2.0	1.3	1.4	1.2	1.4	-0.2	1.1
Arm fat-free mass (right)	0.6	3.3	5.5	1.7	-1.7	-1.5	-2.2	-1.5	-2.3	-0.8	-2.4
Exposure to tobacco smoke outside home	0.5	0.7	1.8	-0.8	0.9	1.3	0.6	-0.0	0.6	-1.3	0.3
Comparative body size at age 10	2.6	7.3	11.2	-3.1	3.1	3.3	2.8	0.6	3.3	-1.3	2.6
Number of full brothers	0.5	0.6	2.4	-0.9	0.8	0.9	0.2	-1.5	0.6	-0.2	0.1
Worry too long after embarrassment	0.5	0.9	2.6	-0.8	-0.1	1.1	-0.2	-1.5	-0.3	-1.6	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	5.7	2.4	-1.7	-1.8	-1.1	0.7	-1.5	2.1	-0.5
Wheeze or whistling in the chest in last year	0.2	0.3	0.6	-0.6	-0.5	0.6	-0.4	-0.5	-0.5	-0.3	-0.8
Number of children fathered	1.8	2.0	9.7	-0.0	-0.0	-0.8	0.8	3.1	0.6	1.7	1.4
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	7.6	0.7	-0.3	-1.1	1.2	2.8	0.8	2.6	1.6
Age at first live birth	0.3	0.5	1.2	0.9	-0.3	-1.1	0.6	0.7	-0.1	0.8	0.6
Pulse wave peak to peak time	0.4	0.5	2.1	-1.5	0.4	0.7	0.2	-1.1	0.3	-0.3	-0.1
Health satisfaction	0.1	0.1	0.5	0.7	0.1	-0.6	-0.2	0.4	-0.2	0.0	-0.1
Shortness of breath walking on level ground	0.1	0.2	0.7	-0.1	0.5	0.4	0.8	0.1	0.2	0.2	0.0
Qualifications: College or University degree	0.1	0.5	1.4	-0.1	-0.8	-0.3	-0.5	-0.8	-0.6	-1.2	-0.6
Eye problems/disorders: None of the above	1.8	2.1	3.8	-0.1	-2.0	-0.6	-1.8	-1.4	-1.6	-1.2	-1.8
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.1	0.8	-1.1	-1.8	-0.9	-0.5	-0.9	1.2	-0.6
Emphysema/chronic bronchitis	2.3	2.6	6.5	-2.3	1.5	2.5	0.8	-1.3	1.3	-1.6	0.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.4	-0.0	-0.6	-0.4	-0.5	-0.6	-0.5	-0.4	-0.7
Neck or shoulder pain in last month	1.7	2.4	4.3	0.3	-1.8	-0.4	-1.7	-1.9	-1.8	-1.4	-2.1
Medication: Blood pressure	3.4	6.0	9.8	-2.5	3.0	2.4	3.0	0.3	3.1	1.1	2.5
Angina (self-reported)	2.9	3.8	8.6	-0.7	2.9	2.2	2.5	0.5	2.4	0.5	2.1
Migraine (self-reported)	0.2	0.3	0.5	-0.7	0.2	0.4	0.1	0.5	0.6	0.4	0.7
Medication: Ibuprofen	2.3	2.8	4.4	1.1	-1.9	-1.3	-2.0	-1.2	-2.1	-1.4	-2.0
Medication: Allopurinol	0.8	1.0	1.6	-1.2	1.3	1.0	1.2	0.5	1.2	-0.1	1.0
Medication: Omeprazole	2.2	2.6	4.3	-0.8	1.7	0.9	2.1	1.5	1.9	1.7	1.9
Medication: Seretide 50 evohaler	0.2	0.2	0.7	-0.8	-0.6	-0.1	-0.8	-0.2	-0.2	0.5	-0.2
Mean time to correctly identify matches	0.5	1.0	3.1	1.2	-0.7	-1.8	-1.0	0.9	-0.8	0.9	-0.0
Heart disease (mother)	4.7	5.8	10.3	-1.7	2.6	2.0	3.1	1.5	3.2	1.3	3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	4.9	-0.4	-0.7	0.1	-1.3	-2.2	-1.1	-2.1	-2.1
Whole body fat mass	0.1	0.3	0.5	0.7	0.7	0.6	-0.2	-0.3	-0.1	-0.7	-0.6
Leg fat mass (right)	0.1	0.5	1.9	0.6	1.4	1.0	0.4	0.1	0.5	-0.6	0.0
Arm predicted mass (right)	0.5	2.8	4.5	1.7	-1.6	-1.6	-2.0	-1.1	-2.1	-0.3	-2.0
Pulse rate, automated reading	0.6	1.9	4.1	-1.4	2.0	2.0	0.5	-1.1	1.2	-1.5	0.1
Alcohol intake frequency.	0.6	1.4	3.4	-1.4	1.9	1.5	0.4	-0.7	1.4	0.6	0.4
Comparative height size at age 10	1.2	6.8	13.8	2.2	-3.7	-3.2	-2.9	0.3	-3.5	-0.1	-2.2
Number of full sisters	0.0	0.0	0.1	-0.1	-0.1	0.2	0.1	0.0	-0.2	-0.0	-0.4
Suffer from ‘nerves’	0.5	0.9	3.7	0.1	-0.0	0.1	-1.1	-1.9	-0.6	-0.6	-1.1
Overall health rating	0.3	0.6	1.3	-1.1	0.9	0.7	0.7	0.3	0.8	-0.8	0.7
Chest pain or discomfort	1.0	1.5	3.2	-1.7	1.4	1.8	0.7	-1.1	1.1	-0.8	0.4
Had major operations	0.5	0.6	2.2	1.2	-0.2	-1.0	-0.3	0.6	-0.4	1.5	0.2
Age at last live birth	0.1	0.1	0.3	0.2	-0.2	-0.5	0.4	0.5	-0.0	0.3	0.5
Family relationship satisfaction	0.4	0.5	1.2	1.1	-0.6	-1.0	-0.7	0.1	-0.8	0.2	-0.4
Leg pain on walking	0.1	0.2	0.5	-0.3	0.7	0.2	0.3	-0.4	0.3	-0.5	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.7	0.6	-0.2	-0.7	-0.9	0.0	-0.6	0.5	-0.6
Commuting to job workplace: Car/motor vehicle	0.5	0.5	2.0	-1.1	0.1	0.5	-0.4	-1.4	-0.1	-0.4	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.8	-0.2	-0.9	-0.4	-0.3	-0.4	-0.8	-0.8	-0.5
Medication: Aspirin	1.4	1.9	5.2	0.5	2.3	1.1	1.5	0.4	1.6	0.9	1.7
Supplements: Vitamin C	2.0	2.3	5.5	0.9	-2.4	-2.3	-1.1	1.4	-1.5	1.2	-0.3
Knee pain experienced in last month	0.9	1.4	2.9	-0.5	1.7	1.6	1.4	-1.1	1.2	-0.8	0.7
Hypertension (Self-reported)	3.4	9.5	17.5	-2.2	4.2	3.1	3.7	1.2	4.0	0.7	3.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.6	-0.2	0.1	0.5	0.3	0.4	0.3	0.8	0.4
Illnesses of father: Heart disease	4.1	5.7	9.4	-1.5	2.7	2.6	3.1	1.4	3.0	1.3	2.6
Illnesses of siblings: Diabetes	1.8	2.3	4.1	-1.4	2.0	1.8	1.6	-0.1	1.9	0.5	1.5
Smoking status: Previous	0.3	0.4	1.3	0.8	-0.5	-0.7	-0.6	0.1	-0.5	1.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.0	13.9	3.1	-3.3	-3.7	-1.2	2.2	-2.5	1.1	-0.7
Whole body fat-free mass	0.5	3.0	5.4	1.5	-1.5	-1.5	-2.1	-1.6	-2.1	-0.4	-2.3
Leg fat-free mass (right)	0.4	2.2	4.4	1.1	-1.3	-1.2	-1.8	-1.6	-1.8	-0.3	-2.1
Arm fat percentage (left)	0.2	0.7	1.9	0.0	1.3	1.4	0.4	-0.2	0.6	-1.1	-0.1
Average weekly red wine intake	2.1	3.1	8.9	2.4	-1.5	-3.0	-0.6	1.8	-1.4	1.3	0.0
Handedness (chirality/laterality): Left-handed	1.7	2.1	4.5	-1.4	1.7	1.9	1.2	-0.6	2.1	0.6	1.1
Mood swings	1.6	2.8	6.3	-2.5	1.3	2.5	0.2	-1.7	1.0	-2.1	-0.5
Loneliness, isolation	0.2	0.3	1.2	0.5	-0.3	-0.3	-0.1	1.1	-0.2	0.7	0.2
Long-standing illness, disability or infirmity	8.8	13.5	22.5	-3.1	4.2	3.2	4.3	2.6	4.7	1.6	4.4
Ever had bowel cancer screening	0.7	0.8	2.3	-0.1	0.3	-0.1	1.1	1.5	0.7	0.8	1.2
Diabetes diagnosed by doctor	3.5	5.7	9.5	-2.6	2.9	2.5	2.4	1.1	3.1	0.3	2.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.3	1.2	-0.9	-0.7	-0.7	-0.3	-0.9	-0.1	-0.6
Friendships satisfaction	2.4	3.0	8.0	2.8	-1.2	-2.4	-0.3	2.4	-1.2	1.2	0.5
Qualifications: nursing, teaching	1.5	2.3	4.3	-1.0	1.1	0.8	2.1	1.7	1.7	1.2	2.0
Commuting to job workplace: Walk	2.1	2.3	4.8	2.0	-2.2	-2.0	-1.1	1.3	-1.5	0.0	-0.4
Eye problems/disorders: Cataract	3.5	4.1	7.6	1.0	1.7	-0.3	2.6	2.1	1.9	2.4	2.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.9	-0.8	0.3	-0.1	1.1	1.2	0.8	1.7	1.0
Medication for cholesterol	3.3	5.0	11.0	1.9	-2.9	-3.3	-2.2	0.1	-2.8	0.4	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.7	0.7	-0.8	-0.8	-0.3	0.7	-0.6	-0.2	0.0
Back pain experienced in last month	1.0	1.4	3.5	-1.0	1.7	1.9	0.8	-0.8	1.2	-0.9	0.5
Mineral and other dietary supplements	0.2	0.2	0.8	-0.2	0.7	0.3	0.9	-0.1	0.6	-0.2	0.3
Breast cancer (self-reported)	0.2	0.2	1.0	1.0	-0.1	-0.5	-0.1	0.5	-0.2	0.4	-0.1
Asthma (self-reported)	0.4	0.7	1.9	-0.2	0.5	0.6	0.9	1.4	0.8	1.0	0.8
Osteoporosis (self-reported)	0.3	0.4	1.2	-1.0	-0.0	0.7	-0.0	-0.3	0.0	-1.1	-0.4
Osteoarthritis (self-reported)	0.5	0.6	1.5	-0.3	0.3	0.2	0.9	1.2	0.8	0.6	1.2
Medication: Aspirin	1.5	1.9	5.0	0.5	2.2	1.2	1.5	0.4	1.6	0.9	1.7
Medication: Gliclazide	1.8	2.0	4.6	-2.1	1.5	1.9	1.0	-0.7	1.7	-0.5	1.0
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	-0.4	-0.3	-0.6	-0.1	-0.4	-0.2	-0.2	-0.4
Smoking status: Current	3.1	4.9	8.0	2.3	-1.9	-1.8	-2.5	-1.7	-2.8	-1.7	-2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	5.5	10.1	1.5	-3.2	-2.7	-3.0	-0.7	-2.9	-0.7	-2.4
Whole body water mass	0.5	3.1	5.3	1.7	-1.6	-1.6	-2.1	-1.5	-2.2	-0.3	-2.3
Leg predicted mass (right)	0.4	2.3	4.6	1.2	-1.3	-1.2	-1.9	-1.7	-1.8	-0.4	-2.2
Arm fat mass (left)	0.1	0.6	1.3	0.7	0.5	0.6	-0.6	-0.9	-0.4	-1.1	-1.0
Number of self-reported non-cancer illnesses	6.9	11.9	20.3	-2.8	3.9	3.0	4.1	2.4	4.5	1.6	4.2
Average weekly champagne plus white wine intake	0.3	0.3	0.9	0.5	-0.1	-0.3	0.2	1.0	0.2	0.9	0.8
Miserableness	2.7	4.6	10.6	-3.2	2.4	3.3	1.2	-1.1	2.0	-1.7	0.8
Guilty feelings	0.7	1.1	2.1	0.3	-1.4	-0.7	-1.4	-0.7	-1.3	-0.5	-1.3
Wears glasses or contact lenses	1.2	1.3	2.6	-1.3	1.4	1.6	1.1	0.3	1.5	-0.3	0.9
Ever taken oral contraceptive pill	0.8	0.9	1.6	-1.1	1.1	1.3	1.1	-0.1	1.0	-0.9	0.6
Hearing aid user	0.9	1.1	2.5	0.1	0.5	-0.1	0.8	1.3	0.9	1.5	1.6
Mother’s age at death	0.1	0.1	0.3	-0.3	-0.1	-0.2	-0.1	0.5	-0.3	-0.5	-0.2
Financial situation satisfaction	4.1	5.1	8.8	2.3	-2.4	-2.7	-2.8	-0.1	-3.0	-1.2	-2.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	-0.6	0.5	0.6	0.5	-0.3	0.5	-0.9	0.5
Commuting to job workplace: Public transport	0.9	1.1	1.6	-0.6	1.3	1.2	1.1	1.0	1.2	0.3	1.1
Eye problems/disorders: Glaucoma	2.4	2.8	6.8	0.3	-0.8	0.3	-2.1	-1.3	-1.7	-2.6	-2.4
Medication: Blood pressure	2.8	5.3	10.1	-1.5	3.2	3.0	2.5	0.5	2.9	-0.7	2.4
Pain type(s) experienced in last month: Hip pain	1.4	1.8	4.1	-1.1	2.0	1.9	1.1	-0.1	1.6	-0.4	1.0
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.7	0.9	-0.5	-0.5	-0.3	0.5	-0.3	0.7	0.3
High cholesterol (Self-reported)	3.0	5.3	11.9	-2.0	3.0	3.5	2.3	-1.0	2.8	-0.1	1.8
Medication: Bendroflumethiazide	0.6	0.9	2.2	0.2	1.0	0.8	1.5	0.8	1.2	-0.1	1.3
Medication: Paracetamol	0.6	0.9	3.4	-0.1	-0.2	-0.8	-0.1	1.9	0.3	1.2	1.1
Medication: Lisinopril	1.8	2.3	4.1	-1.4	1.6	1.1	2.0	0.8	1.9	1.1	1.7
Medication: Atorvastatin	0.7	0.9	2.0	-1.1	1.0	1.4	-0.1	-1.3	0.5	-0.8	-0.2
Illnesses of father: High blood pressure	0.2	0.2	0.5	-0.1	-0.4	0.1	-0.5	-0.6	-0.4	-0.7	-0.2
Alcohol drinker status: Never	0.1	0.1	0.3	0.4	0.5	-0.3	-0.5	-0.1	-0.0	0.1	-0.1
Ever smoked	2.5	4.4	7.4	1.9	-2.2	-2.0	-2.6	-1.2	-2.7	-0.6	-2.6
Basal metabolic rate	0.5	3.0	5.3	1.7	-1.5	-1.4	-2.1	-1.4	-2.1	-0.6	-2.3
Leg fat percentage (left)	0.4	1.3	4.0	0.4	2.0	1.4	1.2	0.6	1.3	-0.6	0.8
Arm fat-free mass (left)	0.7	3.6	6.2	2.0	-1.5	-1.5	-2.4	-1.6	-2.3	-0.6	-2.5
Number of operations (self-reported)	0.8	1.1	3.2	1.7	-0.6	-1.3	0.0	1.8	-0.4	0.5	0.6
Average weekly beer plus cider intake	1.2	1.7	4.2	-0.3	-0.5	0.7	-1.3	-1.8	-1.0	-2.0	-1.6
Irritability	2.3	4.0	8.3	-2.4	2.6	2.9	1.8	-1.0	2.3	-0.3	1.1
Risk taking	0.1	0.1	0.8	-0.0	-0.4	-0.1	-0.0	0.9	0.0	0.3	0.2
Ever had prostate specific antigen (PSA) test	1.2	1.4	5.0	0.5	-0.5	-1.0	0.2	2.2	0.2	2.0	0.9
Fractured/broken bones in last 5 years	0.2	0.2	0.7	-0.3	0.4	0.5	0.5	0.2	0.4	-0.9	0.1
Age started oral contraceptive pill	0.7	0.8	2.2	-0.9	0.6	1.3	-0.1	-1.2	0.4	-1.5	-0.3
Diastolic blood pressure, automated reading	0.4	1.2	3.2	-0.7	1.8	1.8	0.4	-1.1	1.0	-0.9	0.0
Ever depressed for a whole week	0.5	0.6	1.3	-0.8	1.0	1.1	0.1	-0.1	0.6	-1.1	0.0
Unable to work because of sickness or disability	0.4	0.5	0.9	-0.9	0.6	1.0	0.5	-0.2	0.9	0.4	0.7
Commuting to job workplace: Cycle	1.0	1.3	2.6	-1.3	1.2	1.6	1.1	-0.8	1.2	-0.7	0.6
Myopia	1.9	2.8	5.0	-2.2	1.7	2.2	2.1	0.2	2.0	-0.2	1.0
Vascular/heart problems diagnosed by doctor	7.0	19.1	33.9	3.7	-5.8	-5.0	-5.2	-1.1	-5.6	-0.8	-4.5
Cholesterol lowering medication	3.6	5.4	9.8	-2.2	3.1	3.1	2.4	-0.8	2.8	-0.7	2.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.0	-0.4	1.4	1.0	1.2	0.4	1.2	1.1	0.9
Pain experienced in last month	0.9	1.5	3.9	0.6	-1.2	-2.0	-0.6	1.7	-0.6	1.7	0.2
Supplements: Calcium	0.4	0.4	1.1	-1.1	-0.6	0.3	-0.6	-1.0	-0.1	-0.7	-0.4
Basal cell carcinoma (self-reported)	1.1	1.4	7.4	0.0	0.1	-0.6	1.3	2.7	0.4	0.5	1.0
Heart attack/myocardial infarction (self-reported)	3.0	3.8	8.1	-1.2	2.9	2.1	2.3	0.3	2.5	0.1	2.2
Deep venous thrombosis (DVT) (self-reported)	2.1	2.6	6.2	-1.4	2.5	2.5	1.2	-0.8	2.0	0.3	0.9
Heart disease (siblings)	0.8	1.0	2.6	-0.1	1.6	1.4	0.9	-0.7	1.1	0.6	0.8
Alcohol drinker status: Previous	0.5	0.5	1.3	-0.6	1.1	1.2	0.5	-0.2	0.8	0.3	0.5
Pack years of smoking	0.9	1.3	2.4	-1.5	1.5	1.4	0.9	-0.0	1.4	-0.3	0.9
Impedance of whole body	0.2	1.0	2.7	0.3	-1.6	-1.3	-0.1	1.4	-0.6	0.9	0.4
Leg fat mass (left)	0.1	0.5	1.6	0.5	1.3	1.0	0.2	-0.2	0.4	-0.8	-0.2
Arm predicted mass (left)	0.7	3.6	6.4	2.0	-1.5	-1.5	-2.4	-1.7	-2.3	-0.5	-2.5