Hub : Genes

CEP70

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Esophagus Mucosa 0.1520 0.0640 9.5e-05 0.035 NA 0.076 NA 0.044 2.1e-03 NA 8.4e-06 NA 6.5e-04
2 GTEx Muscle Skeletal 0.0800 0.0324 1.2e-04 0.056 NA 0.057 NA 0.058 3.4e-06 NA 2.8e-06 NA 2.1e-06
3 GTEx Testis 0.1880 0.0760 2.1e-04 0.042 NA 0.083 NA 0.088 5.9e-03 NA 1.6e-04 NA 1.0e-04
4 GTEx Thyroid 0.1740 0.0560 7.9e-05 0.010 NA 0.038 NA 0.028 5.3e-02 NA 6.8e-04 NA 3.1e-03
5 YFS Blood 0.0468 0.0140 2.3e-09 0.033 0.035 0.028 0.038 0.031 4.4e-11 1.4e-11 1.5e-09 1.9e-12 2.1e-10
6 TCGA Brain Lower Grade Glioma 0.0345 0.0183 3.0e-04 0.025 0.023 0.024 NA 0.016 6.0e-04 1.1e-03 9.0e-04 NA 4.9e-03
7 TCGA Prostate Adenocarcinoma 0.2332 0.0864 2.9e-06 0.038 0.046 0.037 NA 0.035 6.5e-05 1.4e-05 8.8e-05 NA 1.3e-04
8 TCGA Thyroid Carcinoma 0.0390 0.0250 9.7e-03 0.004 0.020 0.011 NA 0.013 1.3e-01 4.5e-03 2.7e-02 NA 1.7e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.0 1.6 3.9 -1.8 -0.2 0.7 -0.6 -1.9 -0.1 -2.0 -0.9
Bipolar Disorder or Schizophrenia 0.5 1.2 3.2 -1.8 0.7 1.6 0.5 -0.8 0.9 -1.1 0.0
Depressed Affect (Nagel 2018) 2.8 6.0 13.8 -3.3 3.0 3.7 1.5 -0.7 2.6 -1.6 1.3
Depression (Nagel 2018) 0.5 0.7 1.8 -1.1 0.9 1.3 0.3 0.8 0.9 -0.3 0.6
Intelligence (Savage-Jansen 2018) 2.0 6.3 10.6 -2.1 3.0 2.4 3.0 0.6 3.3 1.4 3.0
Neuroticism (Nagel 2018) 1.6 3.8 8.0 -2.8 2.2 2.8 1.5 -0.7 2.0 -1.4 1.2
Schizophrenia (2018) 0.5 1.0 2.5 -0.9 1.1 1.6 1.1 0.5 1.3 0.2 0.7
Schizophrenia vs Biploar Disorder 1.4 1.9 3.3 1.3 -1.7 -1.0 -1.7 -0.1 -1.7 -0.5 -1.8
Worry (Nagel 2018) 0.3 0.7 2.2 -0.9 0.2 0.6 -0.3 -1.5 0.0 -1.3 -0.5
Alzheimer’s Disease (in mother) 1.7 1.9 3.8 -0.0 1.4 0.3 1.3 1.8 1.5 1.5 1.9
Alzheimer’s Disease (in father) 0.3 0.4 1.5 -0.4 0.6 0.7 0.2 -1.2 0.1 -0.5 -0.2
Alzheimer’s Disease (including proxy) 1.1 1.6 2.8 -0.5 1.7 1.1 1.5 0.5 1.5 1.0 1.6
Crohns Disease (2017) 0.7 1.5 4.9 -0.2 0.2 0.9 -1.3 -2.2 -0.5 -1.7 -1.3
Irritable Bowel Disease (IBD) 0.5 1.1 4.0 0.2 0.1 0.3 -1.1 -2.0 -0.8 -0.8 -1.4
Ulcerative Colitis (UC) 0.2 0.3 0.9 0.2 0.1 -0.1 -0.4 -1.0 -0.5 0.5 -0.8
Major Depression (MDD) 0.1 0.2 0.4 -0.0 0.2 0.6 0.5 0.5 0.4 -0.2 0.4
Reaction Time 0.3 0.5 1.6 0.7 -0.5 -1.3 -0.8 0.9 -0.5 -0.0 0.2
Verbal and Numeric Reasoning (VNR) 2.5 5.9 9.5 -3.1 2.5 3.1 2.6 -0.2 2.9 -1.0 2.5
Breast Cancer 1.2 3.0 7.5 -1.7 2.0 2.7 1.3 -1.2 1.6 -1.8 0.5
Ovarian Cancer 1.4 1.8 4.8 2.2 -1.3 -2.0 -0.6 -0.0 -1.6 0.3 -1.1
Prostate Cancer 0.1 0.2 0.9 0.9 -0.2 0.2 0.1 0.0 -0.1 -0.6 -0.2
Age at First Birth 1.7 2.5 5.4 2.3 -1.4 -2.3 -0.1 2.0 -1.4 1.2 0.2
Bipolar Disorder (2011) 0.9 0.8 2.5 -1.5 0.4 1.1 -0.4 -1.6 0.3 -0.4 -0.4
Body Mass Index (BMI) (2010) 2.4 3.2 5.6 -1.9 2.2 2.4 2.0 0.6 2.2 -0.6 1.4
Coronary Artery Disease (CAD) 2.8 3.3 5.4 -0.3 2.1 1.0 2.1 1.7 2.2 1.9 2.3
Crohns Disease (2012) 1.3 2.1 4.4 -1.4 0.1 1.4 -1.3 -2.1 -0.3 -2.0 -1.4
Mean Putamen Volume 0.9 1.1 2.8 1.1 -1.1 -1.7 -0.9 0.2 -1.0 1.1 -0.6
Fasting Glucose 1.2 1.4 3.5 -0.2 1.5 0.6 1.9 1.0 1.4 0.7 1.2
HbA1C 1.0 1.1 2.6 -1.5 0.7 0.4 1.0 0.9 1.1 0.1 1.6
HDL Cholesterol 0.2 0.4 1.1 0.4 -0.8 -1.1 0.1 0.6 -0.3 0.7 0.1
LDL Cholesterol 1.2 1.9 5.2 -1.9 1.4 2.3 0.8 -0.7 1.4 -0.7 0.9
Lupus 0.6 1.0 3.8 0.9 -0.4 -0.7 0.5 2.0 0.1 1.2 0.9
Neuroticism (2016) 0.9 1.4 3.7 0.4 1.5 0.4 1.3 0.6 1.2 1.1 1.9
Primary Biliary Cirrhosis 2.9 4.1 6.9 -1.8 2.2 1.7 2.5 1.4 2.5 0.7 2.6
Rheumatoid Arthritis 0.9 1.2 2.0 1.3 -1.2 -0.3 -1.4 -0.5 -1.2 -1.2 -1.2
Schizophrenia (2014) 0.1 0.2 0.9 -0.5 0.2 1.0 0.0 0.1 0.4 -0.2 -0.2
Triglycerides 0.4 0.6 1.4 -0.7 0.7 1.2 -0.1 -1.1 0.4 -1.2 -0.1
Type 2 Diabetes (T2D) (2012) 1.9 2.1 4.7 -1.7 1.8 2.2 1.4 -0.1 1.8 0.0 1.0
Ulcerative Colitis 0.3 0.4 1.0 0.6 0.0 -0.1 -0.4 -1.0 -0.8 -0.4 -1.0
Blood Eosinophil Count 0.7 5.2 17.4 4.2 -1.9 -3.1 -2.0 1.5 -2.2 0.2 -0.4
Blood Platelet Count 1.0 11.3 25.4 4.9 -3.6 -5.0 -1.8 3.6 -3.2 1.3 -0.1
Blood Red Count 0.0 0.2 0.6 0.4 0.1 -0.5 -0.3 0.8 -0.1 -0.2 -0.0
Blood White Count 0.2 1.3 2.8 -0.5 1.4 0.8 1.7 0.5 1.4 -0.1 1.6
Heel T-Score 1.3 10.6 17.1 3.8 -4.0 -4.1 -3.7 0.1 -4.1 -0.4 -2.6
BMI 0.2 1.0 2.9 -0.2 1.7 1.4 0.8 0.2 1.0 -0.9 0.7
Height 0.7 14.1 23.4 3.9 -4.8 -4.7 -3.9 -0.1 -4.7 1.5 -3.6
Waist Hip Ratio (WHR) 3.5 15.8 26.6 -3.6 4.9 4.8 4.3 1.2 5.2 1.5 4.2
Systolic Blood Pressure 0.4 1.8 3.8 -1.8 1.7 2.0 0.9 -0.4 1.6 -0.1 0.8
Smoking Status 0.7 1.7 3.1 1.5 -0.8 -0.7 -1.5 -1.4 -1.6 -0.7 -1.8
Allergy or Eczema 0.0 0.1 0.1 0.1 -0.2 -0.1 0.4 0.3 0.2 -0.2 0.4
Cardiovascular Disease 3.4 11.4 18.8 -1.8 4.3 3.6 4.3 1.3 4.3 0.6 4.1
Hypothyroidism (self reported) 0.6 1.3 4.0 1.5 0.6 -0.5 1.2 1.0 0.6 2.0 1.1
Respiratory disease 0.8 1.7 5.0 -1.5 1.7 2.2 0.8 -0.3 1.4 -0.8 0.6
Type 2 Diabetes (T2D) (2018) 4.5 8.4 14.5 -2.5 3.6 2.9 3.4 1.4 3.8 0.6 3.4
Lung FEV1/FVC ratio 0.0 0.1 0.5 -0.4 0.3 -0.0 0.2 0.7 0.3 0.3 0.4
Lung FVC 2.4 12.4 22.0 4.7 -4.1 -4.7 -3.3 0.7 -4.1 1.4 -2.9
Neuroticism 1.3 3.0 7.5 -2.6 1.4 2.7 0.4 -1.8 1.2 -1.8 0.2
Chronotype (morning person) 2.4 5.5 12.7 2.5 -2.9 -3.6 -2.1 1.4 -2.6 1.2 -1.3
Hair Pigment 0.2 4.6 10.4 -3.2 2.3 2.9 1.7 -0.5 2.3 -1.7 1.2
Tanning 0.1 1.4 2.6 0.4 -1.6 -1.2 -1.5 0.1 -1.5 0.7 -1.4
Hand grip strength (left) 0.7 2.0 4.0 1.4 -2.0 -1.4 -1.5 -0.5 -1.7 -0.1 -1.5
Number of treatments/medications taken 7.9 14.2 23.6 -3.5 4.6 4.1 4.2 1.8 4.9 0.6 4.2
Average weekly spirits intake 0.5 0.6 1.7 -1.0 0.4 0.3 1.0 0.8 0.7 -0.5 1.3
Sensitivity / hurt feelings 0.1 0.1 0.2 -0.2 0.3 0.3 0.5 0.5 0.2 -0.5 0.2
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.8 -0.9 -0.1 0.6 -0.0 0.4 0.2 0.1 0.1
Hearing difficulty/problems: Yes 1.4 2.2 4.7 -1.6 2.2 1.8 1.6 0.1 1.9 -0.3 0.9
Relative age of first facial hair 0.2 0.5 1.1 -0.7 -0.4 0.8 -0.4 -0.9 -0.3 -1.0 -0.6
Other serious medical condition/disability diagnosed by doctor 4.7 6.1 11.1 -1.5 3.3 1.7 2.9 1.7 3.2 1.2 3.0
Ever used hormone-replacement therapy (HRT) 1.1 1.4 4.1 0.8 -1.2 -1.7 -0.1 2.0 -0.3 1.3 0.8
Ever had hysterectomy (womb removed) 0.1 0.1 0.4 0.5 0.3 -0.2 0.3 -0.1 0.2 0.6 0.1
Systolic blood pressure, automated reading 0.6 1.6 3.8 -1.4 2.0 1.7 0.8 -0.5 1.6 0.2 0.8
Eye problems/disorders: Diabetes related eye disease 3.8 4.2 7.1 -2.0 1.9 1.1 2.4 2.2 2.5 0.9 2.7
Angina 3.3 4.4 9.8 -0.9 3.1 2.4 2.6 0.3 2.6 0.3 2.2
Medication for hormone replacement therapy 0.5 0.5 1.0 0.6 -1.0 -0.5 -0.9 0.2 -0.9 0.6 -0.8
Vitamin and mineral supplements 1.7 2.3 6.1 -0.7 2.0 2.5 0.9 -2.3 1.1 -0.9 -0.3
Supplements: Zinc 0.5 0.6 3.3 -1.8 0.2 0.3 0.2 -0.4 0.7 0.3 0.7
Medication: Co-codamol 3.5 4.1 7.8 -0.4 2.5 1.5 2.8 1.6 2.5 0.5 2.8
Medication: Metformin 1.3 1.8 2.9 -1.7 1.6 1.4 1.3 0.2 1.6 -0.6 1.4
Diabetes (father) 0.2 0.2 1.4 0.4 -0.3 -0.2 -0.2 1.2 -0.4 -0.2 -0.0
Diabetes (mother) 0.6 0.7 2.1 -1.4 0.5 1.0 1.0 -0.0 0.9 -0.3 0.8
Severe depression (siblings) 0.1 0.2 0.9 -0.9 -0.0 -0.0 -0.3 0.3 0.1 0.3 0.2
Pack years adult smoking proportion 1.1 1.7 3.1 -1.7 1.8 1.7 1.0 -0.2 1.6 -0.5 1.0
Impedance of leg (right) 0.2 0.9 3.1 0.6 -1.1 -0.9 0.1 1.8 -0.4 0.8 0.6
Leg fat-free mass (left) 0.4 2.1 4.0 1.2 -1.3 -1.2 -1.8 -1.3 -1.8 -0.3 -2.0
Trunk fat percentage 0.0 0.2 0.5 0.7 0.4 0.3 -0.1 0.0 -0.1 -0.6 -0.4
Hand grip strength (right) 1.6 4.4 8.5 1.9 -2.9 -2.1 -2.0 -0.7 -2.8 -1.3 -2.1
Townsend deprivation index at recruitment 0.2 0.3 1.7 1.3 0.4 -0.6 0.2 0.2 -0.3 0.4 0.1
Current tobacco smoking 2.0 3.2 5.2 1.8 -1.4 -1.2 -1.9 -1.4 -2.3 -1.8 -2.1
Average weekly fortified wine intake 0.4 0.5 1.2 0.5 -0.6 -0.3 -1.1 -0.7 -0.7 -0.4 -0.7
Maternal smoking around birth 1.1 1.6 5.5 0.9 -0.3 -1.3 1.1 1.3 0.3 2.4 1.2
Fed-up feelings 1.9 3.4 8.7 -2.2 2.3 2.9 0.5 -1.6 1.3 -2.0 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.9 0.4 -0.5 -0.3 -1.0 0.2 -0.8 -0.3 -0.8
Relative age voice broke 0.9 1.3 4.6 -1.4 0.9 2.1 0.9 -0.6 0.9 -1.2 0.2
Taking other prescription medications 7.6 11.7 20.6 -3.0 4.3 3.6 3.9 1.0 4.5 1.1 3.9
Age when periods started (menarche) 2.7 6.4 10.0 2.2 -2.9 -2.8 -2.9 -1.5 -3.2 0.9 -2.9
Bilateral oophorectomy (both ovaries removed) 3.3 3.8 10.5 3.2 -0.8 -2.4 0.1 2.2 -0.6 2.7 0.8
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.4 5.2 2.3 -1.5 -1.7 -1.4 -0.2 -1.9 -0.3 -1.6
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 2.5 1.0 -1.4 -0.6 -1.3 0.0 -1.6 -1.2 -1.4
Qualifications: CSEs or equivalent 0.7 0.9 1.5 0.4 -0.8 -0.3 -1.2 -0.9 -1.2 -1.1 -1.1
Serious illness, injury or assault to yourself 2.6 3.2 5.6 0.0 2.1 1.0 2.1 1.8 2.0 1.8 2.4
High blood pressure 4.5 12.5 21.7 -3.0 4.7 3.9 4.2 1.1 4.6 0.8 3.7
Hayfever, allergic rhinitis or eczema 0.1 0.1 0.6 0.1 -0.8 0.1 -0.2 -0.2 -0.3 -0.5 -0.4
Multivitamins +/- minerals 3.0 3.8 11.4 1.6 -2.6 -3.4 -1.2 2.1 -1.6 1.3 0.1
Stomach or abdominal pain in last month 0.5 0.7 1.9 -0.8 0.4 1.0 0.2 -1.3 0.3 -1.4 0.0
Supplements: Glucosamine 0.1 0.1 0.2 0.3 -0.3 -0.1 -0.1 0.5 -0.0 0.2 0.4
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.3 -0.4 0.7 0.4 1.1 0.5 0.8 -0.2 1.1
Medication: Atenolol 2.8 3.5 7.1 -0.8 2.7 1.8 2.4 0.6 2.2 0.4 2.3
Medication: Levothyroxine sodium 0.2 0.4 1.0 0.4 0.6 0.1 1.0 0.5 0.6 0.8 0.4
Sitting height 1.2 8.8 19.3 3.1 -4.0 -4.4 -2.7 1.0 -3.5 1.1 -1.9
Chronic bronchitis/emphysema (father) 0.7 0.8 2.1 0.2 0.6 0.2 0.9 1.4 0.8 0.7 1.3
High blood pressure (mother) 3.9 5.4 10.7 -1.2 2.4 1.4 3.2 2.1 2.8 0.5 3.3
Body mass index (BMI) 0.3 1.3 3.8 -0.2 2.0 1.9 0.6 -0.6 1.0 -1.2 -0.0
Impedance of leg (left) 0.1 0.5 1.2 0.5 -1.1 -0.8 -0.0 1.1 -0.4 0.5 0.4
Leg predicted mass (left) 0.4 2.1 4.1 1.3 -1.2 -1.2 -1.8 -1.3 -1.8 -0.3 -2.0
Trunk fat mass 0.1 0.3 0.9 0.9 0.1 0.0 -0.5 -0.2 -0.5 -0.6 -0.8
Waist circumference 0.9 3.4 8.3 -1.3 2.9 2.7 1.7 -0.0 2.3 -0.4 1.2
Number of incorrect matches in round 1.1 1.9 4.0 1.5 -1.7 -2.0 -1.3 1.1 -1.5 0.9 -0.4
Past tobacco smoking 1.7 3.2 4.9 -1.9 1.7 1.8 2.2 1.0 2.2 -0.4 2.2
Alcohol usually taken with meals 3.6 5.8 13.6 2.6 -3.0 -3.7 -1.2 2.6 -2.1 2.0 -0.5
Nervous feelings 0.2 0.3 0.8 -0.6 0.7 0.6 0.1 -0.9 0.4 -0.3 -0.1
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.0 4.8 0.2 -0.8 -0.2 -2.0 -2.2 -1.5 -0.4 -2.1
Hearing difficulty/problems with background noise 0.6 1.0 2.5 -1.5 1.1 1.3 0.4 -0.1 0.9 -1.6 -0.1
Hair/balding pattern: Pattern 2 0.1 0.1 0.4 0.5 -0.5 0.0 -0.2 -0.1 -0.3 0.6 -0.3
Had menopause 0.2 0.3 0.7 0.7 -0.5 -0.7 -0.3 0.8 -0.3 0.6 0.1
Had other major operations 0.9 1.1 1.7 -0.5 1.0 0.2 1.1 1.3 1.3 1.2 1.2
Forced vital capacity (FVC) 2.5 9.7 23.0 3.3 -4.4 -4.8 -2.5 1.1 -3.6 1.3 -1.6
Heel bone mineral density (BMD) T-score, automated (right) 3.0 6.9 12.0 3.2 -2.9 -2.3 -2.9 -0.5 -3.5 -1.2 -3.0
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 3.0 -0.4 1.4 1.7 0.7 0.1 0.8 -1.4 0.2
Qualifications: None of the above 0.5 1.0 3.1 -0.1 -0.1 -0.2 -1.3 -1.8 -0.7 -0.6 -1.6
Financial difficulties in last 2 years 0.4 0.5 1.1 0.5 -0.7 -0.1 -1.1 -0.4 -0.8 -0.7 -1.0
Mouth/teeth dental problems 0.3 0.5 1.3 0.6 -1.0 -0.5 -1.1 -0.3 -0.8 -0.1 -0.8
Heart attack 3.5 4.5 9.1 -1.2 3.0 2.0 2.6 0.6 2.7 0.5 2.5
Allergy 0.2 0.5 1.1 0.6 -0.4 -1.1 -0.9 -0.6 -0.9 -0.2 -0.7
Pain all over the body in last month 0.1 0.1 0.5 -0.5 0.2 0.2 -0.1 -0.7 -0.1 0.1 -0.3
Diabetes (self-reported) 1.7 2.6 4.7 -1.6 1.9 1.3 1.6 0.8 2.1 0.4 2.2
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.7 -0.2 0.0 -0.0 1.3 0.9 0.7 0.6 0.9
Medication: Ramipril 5.5 7.0 12.2 -2.7 3.5 3.5 2.7 -0.3 3.2 -1.4 2.2
Medication: Simvastatin 4.0 5.9 12.1 -1.8 3.5 3.2 2.6 -0.0 3.1 0.3 2.2
Fluid intelligence score 2.3 4.8 10.1 -2.6 2.6 3.2 2.1 -0.6 2.5 -1.2 1.8
Illnesses of siblings 2.2 3.1 5.8 1.4 -2.4 -2.0 -2.2 -0.4 -2.1 -0.6 -1.8
Neuroticism score 0.5 1.1 2.5 -1.3 0.9 1.6 -0.1 -1.6 0.4 -1.1 -0.4
Weight 0.1 0.6 1.5 1.2 -0.3 -0.4 -0.8 -0.3 -0.9 -0.5 -1.1
Impedance of arm (right) 0.1 0.7 1.5 0.1 -1.2 -0.9 0.0 1.2 -0.3 1.1 0.3
Arm fat percentage (right) 0.1 0.5 1.2 0.5 1.1 1.1 0.1 -0.3 0.3 -0.8 -0.3
Trunk fat-free mass 0.7 3.8 6.6 1.7 -1.8 -1.6 -2.4 -1.7 -2.4 -0.7 -2.6
Hip circumference 0.1 0.4 1.4 0.1 0.4 0.6 -0.3 -0.6 -0.1 -1.2 -0.8
Time employed in main current job 0.2 0.3 1.1 -0.6 -0.0 0.6 0.1 -0.5 0.2 -1.0 0.1
Alcohol intake versus 10 years previously 0.5 0.8 2.0 -0.6 1.4 1.0 0.7 0.8 1.1 -0.0 0.9
Father’s age at death 5.4 7.3 14.9 2.6 -3.9 -3.5 -2.7 1.7 -3.2 0.7 -1.8
Worrier / anxious feelings 0.3 0.5 2.0 -1.4 0.3 0.9 0.4 -0.3 0.6 -0.7 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 2.7 0.4 0.5 -0.6 0.9 1.1 0.6 1.6 1.1
Falls in the last year 0.3 0.4 0.9 -1.0 0.4 0.7 0.7 0.4 0.6 -0.3 0.5
Hair/balding pattern: Pattern 3 0.3 0.4 1.7 0.1 0.3 -0.8 0.5 1.3 0.2 -0.0 0.7
Number of live births 1.1 1.6 3.1 -0.4 1.8 1.4 1.8 0.6 1.5 0.1 1.4
Forced expiratory volume in 1-second (FEV1) 2.2 7.4 18.1 2.8 -3.8 -4.2 -2.3 1.3 -3.0 1.2 -1.3
Pulse rate 1.2 2.0 5.1 -1.7 1.7 2.3 0.8 -1.2 1.3 -1.0 0.2
Happiness 0.1 0.1 0.4 0.4 0.3 -0.1 0.1 0.6 0.4 0.4 0.6
Noisy workplace 1.4 1.8 5.2 2.3 -0.9 -1.1 -1.6 0.6 -1.5 0.2 -1.1
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.7 -0.1 -0.2 0.1 0.3 0.0 0.4 0.9 0.6
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.5 -0.4 0.7 0.6 -0.2 -1.1 0.1 -1.6 -0.7
Mouth/teeth dental problems: Dentures 1.7 2.9 5.8 -0.9 2.4 1.7 2.3 0.0 2.1 -0.3 1.9
Asthma 0.6 1.3 2.4 -0.6 0.9 1.0 1.3 1.5 1.3 1.0 1.2
Medication: Ibuprofen (e.g. Nurofen) 2.1 2.7 4.5 1.0 -2.1 -1.5 -2.0 -0.9 -2.1 -1.0 -1.8
Medication: Cholesterol lowering 4.9 7.6 15.2 -2.2 3.9 3.6 3.1 -0.2 3.5 0.7 2.4
Depression (self-reported) 2.6 3.1 5.3 -1.2 1.8 1.4 2.3 1.8 2.1 0.5 2.2
Medication: Lansoprazole 0.7 0.8 3.1 -1.8 0.6 0.8 0.1 -0.7 0.4 -1.3 0.3
Prospective memory result 1.7 2.2 5.0 -2.2 1.3 2.1 -0.1 -1.3 1.1 -1.7 -0.3
Lung cancer (father) 0.3 0.4 1.0 -0.1 -1.0 -0.3 -0.5 -0.0 -0.9 -0.4 -0.8
Illnesses of mother 6.6 8.1 13.5 2.8 -3.5 -3.1 -3.3 -0.8 -3.7 -0.4 -3.2
Forced expiratory volume in 1-second (FEV1), Best measure 3.1 9.9 19.2 3.1 -4.3 -4.4 -3.3 0.4 -3.9 0.6 -2.4
Pulse wave Arterial Stiffness index 0.7 0.9 2.8 1.7 -0.9 -1.1 -0.5 1.2 -0.6 0.3 -0.1
Impedance of arm (left) 0.2 0.9 2.6 -0.1 -1.6 -1.1 0.1 1.5 -0.5 0.7 0.6
Arm fat mass (right) 0.1 0.6 1.3 0.7 0.7 0.7 -0.5 -0.9 -0.3 -1.1 -0.9
Trunk predicted mass 0.7 3.9 6.7 1.7 -1.8 -1.6 -2.4 -1.7 -2.4 -0.7 -2.6
Standing height 1.1 11.2 23.7 3.1 -4.8 -4.9 -2.9 0.7 -4.0 1.5 -2.3
Length of working week for main job 0.7 0.8 1.6 -0.8 -0.6 0.0 -1.1 -1.1 -0.6 -1.3 -0.9
Exposure to tobacco smoke at home 1.1 1.3 2.2 1.3 -1.2 -1.0 -1.4 -0.6 -1.5 -0.1 -1.2
Breastfed as a baby 0.4 0.5 0.9 -0.8 0.9 0.9 0.5 -0.5 0.9 -0.3 0.4
Tense / ‘highly strung’ 0.5 0.8 3.1 -1.0 0.3 0.7 -0.5 -1.8 0.1 -1.0 -0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.7 1.3 -0.1 -0.3 0.4 0.7 0.0 0.7 0.5
Hair/balding pattern: Pattern 4 1.2 2.8 10.5 1.9 -3.2 -1.7 -0.8 0.1 -1.3 1.7 -0.5
Birth weight of first child 0.2 0.4 1.0 -0.2 0.5 -0.4 0.7 0.7 0.6 0.8 1.0
Peak expiratory flow (PEF) 1.9 4.5 12.4 2.3 -2.5 -3.5 -0.7 2.4 -1.5 1.9 0.5
Pulse wave reflection index 0.5 0.6 1.8 1.3 -1.0 -0.6 -0.7 0.2 -0.8 -0.0 -0.5
Ever highly irritable/argumentative for 2 days 0.1 0.2 0.5 -0.6 0.1 0.4 -0.3 -0.2 -0.0 -0.7 -0.2
Loud music exposure frequency 0.7 0.8 1.9 1.4 -0.2 -1.2 0.2 0.7 -0.3 1.2 0.9
Qualifications: O levels/GCSEs or equivalent 1.1 1.8 3.3 -0.6 1.2 1.2 1.8 0.6 1.6 1.3 1.8
Mouth/teeth dental problems: Bleeding gums 1.1 1.5 2.7 0.8 -1.6 -1.6 -1.4 0.0 -1.6 0.4 -1.1
Blood clot in the leg (DVT) 2.2 2.9 7.1 -1.7 2.5 2.7 1.2 -0.9 2.0 0.3 0.9
Medication: Paracetamol 0.5 0.7 3.0 0.2 -0.5 -1.0 -0.3 1.7 -0.0 1.0 0.7
Headache pain in last month 0.1 0.1 0.3 -0.3 -0.0 0.5 0.3 0.2 0.2 -0.6 0.3
Medication for cholesterol, blood pressure or diabetes 4.5 7.4 13.1 2.6 -3.6 -3.3 -3.1 -0.0 -3.5 -1.1 -2.5
Glaucoma (self-reported) 1.7 2.0 6.4 -0.2 -0.4 0.8 -1.4 -1.2 -1.2 -2.5 -1.9
Gout (self-reported) 2.0 2.7 5.1 -1.5 2.3 1.6 2.0 0.3 2.2 0.2 1.7
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 2.5 1.4 -0.1 -0.8 0.6 0.5 0.0 1.6 0.3
Medication: Amlodipine 0.5 0.7 2.4 0.1 0.9 0.4 1.0 -0.1 0.7 1.5 0.7
Medication: Ventolin 100micrograms inhaler 0.6 0.8 1.8 0.1 1.3 1.0 1.0 0.7 1.1 0.2 0.9
Birth weight 2.1 4.5 9.7 -1.6 2.4 2.0 3.1 0.9 2.7 0.7 2.4
Chronic bronchitis/emphysema (mother) 2.1 2.4 5.5 -2.4 0.7 1.6 -0.7 -2.4 0.3 -2.1 -0.6
High blood pressure (siblings) 1.2 1.7 3.1 -1.2 1.4 1.2 1.8 1.0 1.5 0.4 1.6
Forced vital capacity (FVC), Best measure 3.5 13.0 23.7 3.7 -4.9 -4.9 -3.7 0.1 -4.5 0.8 -2.9
Body fat percentage 0.1 0.4 1.2 0.5 1.1 1.0 0.4 0.3 0.5 -0.7 0.1
Leg fat percentage (right) 0.4 1.6 4.0 0.5 2.0 1.3 1.4 1.2 1.4 -0.2 1.1
Arm fat-free mass (right) 0.6 3.3 5.5 1.7 -1.7 -1.5 -2.2 -1.5 -2.3 -0.8 -2.4
Exposure to tobacco smoke outside home 0.5 0.7 1.8 -0.8 0.9 1.3 0.6 -0.0 0.6 -1.3 0.3
Comparative body size at age 10 2.6 7.3 11.2 -3.1 3.1 3.3 2.8 0.6 3.3 -1.3 2.6
Number of full brothers 0.5 0.6 2.4 -0.9 0.8 0.9 0.2 -1.5 0.6 -0.2 0.1
Worry too long after embarrassment 0.5 0.9 2.6 -0.8 -0.1 1.1 -0.2 -1.5 -0.3 -1.6 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 2.0 2.6 5.7 2.4 -1.7 -1.8 -1.1 0.7 -1.5 2.1 -0.5
Wheeze or whistling in the chest in last year 0.2 0.3 0.6 -0.6 -0.5 0.6 -0.4 -0.5 -0.5 -0.3 -0.8
Number of children fathered 1.8 2.0 9.7 -0.0 -0.0 -0.8 0.8 3.1 0.6 1.7 1.4
Reason for reducing amount of alcohol drunk: Health precaution 2.2 2.6 7.6 0.7 -0.3 -1.1 1.2 2.8 0.8 2.6 1.6
Age at first live birth 0.3 0.5 1.2 0.9 -0.3 -1.1 0.6 0.7 -0.1 0.8 0.6
Pulse wave peak to peak time 0.4 0.5 2.1 -1.5 0.4 0.7 0.2 -1.1 0.3 -0.3 -0.1
Health satisfaction 0.1 0.1 0.5 0.7 0.1 -0.6 -0.2 0.4 -0.2 0.0 -0.1
Shortness of breath walking on level ground 0.1 0.2 0.7 -0.1 0.5 0.4 0.8 0.1 0.2 0.2 0.0
Qualifications: College or University degree 0.1 0.5 1.4 -0.1 -0.8 -0.3 -0.5 -0.8 -0.6 -1.2 -0.6
Eye problems/disorders: None of the above 1.8 2.1 3.8 -0.1 -2.0 -0.6 -1.8 -1.4 -1.6 -1.2 -1.8
Mouth/teeth dental problems: Loose teeth 0.9 1.1 3.1 0.8 -1.1 -1.8 -0.9 -0.5 -0.9 1.2 -0.6
Emphysema/chronic bronchitis 2.3 2.6 6.5 -2.3 1.5 2.5 0.8 -1.3 1.3 -1.6 0.2
Medication for pain relief, constipation, heartburn 0.2 0.3 0.4 -0.0 -0.6 -0.4 -0.5 -0.6 -0.5 -0.4 -0.7
Neck or shoulder pain in last month 1.7 2.4 4.3 0.3 -1.8 -0.4 -1.7 -1.9 -1.8 -1.4 -2.1
Medication: Blood pressure 3.4 6.0 9.8 -2.5 3.0 2.4 3.0 0.3 3.1 1.1 2.5
Angina (self-reported) 2.9 3.8 8.6 -0.7 2.9 2.2 2.5 0.5 2.4 0.5 2.1
Migraine (self-reported) 0.2 0.3 0.5 -0.7 0.2 0.4 0.1 0.5 0.6 0.4 0.7
Medication: Ibuprofen 2.3 2.8 4.4 1.1 -1.9 -1.3 -2.0 -1.2 -2.1 -1.4 -2.0
Medication: Allopurinol 0.8 1.0 1.6 -1.2 1.3 1.0 1.2 0.5 1.2 -0.1 1.0
Medication: Omeprazole 2.2 2.6 4.3 -0.8 1.7 0.9 2.1 1.5 1.9 1.7 1.9
Medication: Seretide 50 evohaler 0.2 0.2 0.7 -0.8 -0.6 -0.1 -0.8 -0.2 -0.2 0.5 -0.2
Mean time to correctly identify matches 0.5 1.0 3.1 1.2 -0.7 -1.8 -1.0 0.9 -0.8 0.9 -0.0
Heart disease (mother) 4.7 5.8 10.3 -1.7 2.6 2.0 3.1 1.5 3.2 1.3 3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.2 4.9 -0.4 -0.7 0.1 -1.3 -2.2 -1.1 -2.1 -2.1
Whole body fat mass 0.1 0.3 0.5 0.7 0.7 0.6 -0.2 -0.3 -0.1 -0.7 -0.6
Leg fat mass (right) 0.1 0.5 1.9 0.6 1.4 1.0 0.4 0.1 0.5 -0.6 0.0
Arm predicted mass (right) 0.5 2.8 4.5 1.7 -1.6 -1.6 -2.0 -1.1 -2.1 -0.3 -2.0
Pulse rate, automated reading 0.6 1.9 4.1 -1.4 2.0 2.0 0.5 -1.1 1.2 -1.5 0.1
Alcohol intake frequency. 0.6 1.4 3.4 -1.4 1.9 1.5 0.4 -0.7 1.4 0.6 0.4
Comparative height size at age 10 1.2 6.8 13.8 2.2 -3.7 -3.2 -2.9 0.3 -3.5 -0.1 -2.2
Number of full sisters 0.0 0.0 0.1 -0.1 -0.1 0.2 0.1 0.0 -0.2 -0.0 -0.4
Suffer from ‘nerves’ 0.5 0.9 3.7 0.1 -0.0 0.1 -1.1 -1.9 -0.6 -0.6 -1.1
Overall health rating 0.3 0.6 1.3 -1.1 0.9 0.7 0.7 0.3 0.8 -0.8 0.7
Chest pain or discomfort 1.0 1.5 3.2 -1.7 1.4 1.8 0.7 -1.1 1.1 -0.8 0.4
Had major operations 0.5 0.6 2.2 1.2 -0.2 -1.0 -0.3 0.6 -0.4 1.5 0.2
Age at last live birth 0.1 0.1 0.3 0.2 -0.2 -0.5 0.4 0.5 -0.0 0.3 0.5
Family relationship satisfaction 0.4 0.5 1.2 1.1 -0.6 -1.0 -0.7 0.1 -0.8 0.2 -0.4
Leg pain on walking 0.1 0.2 0.5 -0.3 0.7 0.2 0.3 -0.4 0.3 -0.5 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.7 0.6 -0.2 -0.7 -0.9 0.0 -0.6 0.5 -0.6
Commuting to job workplace: Car/motor vehicle 0.5 0.5 2.0 -1.1 0.1 0.5 -0.4 -1.4 -0.1 -0.4 -0.6
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 0.8 -0.2 -0.9 -0.4 -0.3 -0.4 -0.8 -0.8 -0.5
Medication: Aspirin 1.4 1.9 5.2 0.5 2.3 1.1 1.5 0.4 1.6 0.9 1.7
Supplements: Vitamin C 2.0 2.3 5.5 0.9 -2.4 -2.3 -1.1 1.4 -1.5 1.2 -0.3
Knee pain experienced in last month 0.9 1.4 2.9 -0.5 1.7 1.6 1.4 -1.1 1.2 -0.8 0.7
Hypertension (Self-reported) 3.4 9.5 17.5 -2.2 4.2 3.1 3.7 1.2 4.0 0.7 3.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.2 0.6 -0.2 0.1 0.5 0.3 0.4 0.3 0.8 0.4
Illnesses of father: Heart disease 4.1 5.7 9.4 -1.5 2.7 2.6 3.1 1.4 3.0 1.3 2.6
Illnesses of siblings: Diabetes 1.8 2.3 4.1 -1.4 2.0 1.8 1.6 -0.1 1.9 0.5 1.5
Smoking status: Previous 0.3 0.4 1.3 0.8 -0.5 -0.7 -0.6 0.1 -0.5 1.2 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 2.9 6.0 13.9 3.1 -3.3 -3.7 -1.2 2.2 -2.5 1.1 -0.7
Whole body fat-free mass 0.5 3.0 5.4 1.5 -1.5 -1.5 -2.1 -1.6 -2.1 -0.4 -2.3
Leg fat-free mass (right) 0.4 2.2 4.4 1.1 -1.3 -1.2 -1.8 -1.6 -1.8 -0.3 -2.1
Arm fat percentage (left) 0.2 0.7 1.9 0.0 1.3 1.4 0.4 -0.2 0.6 -1.1 -0.1
Average weekly red wine intake 2.1 3.1 8.9 2.4 -1.5 -3.0 -0.6 1.8 -1.4 1.3 0.0
Handedness (chirality/laterality): Left-handed 1.7 2.1 4.5 -1.4 1.7 1.9 1.2 -0.6 2.1 0.6 1.1
Mood swings 1.6 2.8 6.3 -2.5 1.3 2.5 0.2 -1.7 1.0 -2.1 -0.5
Loneliness, isolation 0.2 0.3 1.2 0.5 -0.3 -0.3 -0.1 1.1 -0.2 0.7 0.2
Long-standing illness, disability or infirmity 8.8 13.5 22.5 -3.1 4.2 3.2 4.3 2.6 4.7 1.6 4.4
Ever had bowel cancer screening 0.7 0.8 2.3 -0.1 0.3 -0.1 1.1 1.5 0.7 0.8 1.2
Diabetes diagnosed by doctor 3.5 5.7 9.5 -2.6 2.9 2.5 2.4 1.1 3.1 0.3 2.8
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.3 1.2 -0.9 -0.7 -0.7 -0.3 -0.9 -0.1 -0.6
Friendships satisfaction 2.4 3.0 8.0 2.8 -1.2 -2.4 -0.3 2.4 -1.2 1.2 0.5
Qualifications: nursing, teaching 1.5 2.3 4.3 -1.0 1.1 0.8 2.1 1.7 1.7 1.2 2.0
Commuting to job workplace: Walk 2.1 2.3 4.8 2.0 -2.2 -2.0 -1.1 1.3 -1.5 0.0 -0.4
Eye problems/disorders: Cataract 3.5 4.1 7.6 1.0 1.7 -0.3 2.6 2.1 1.9 2.4 2.8
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.9 -0.8 0.3 -0.1 1.1 1.2 0.8 1.7 1.0
Medication for cholesterol 3.3 5.0 11.0 1.9 -2.9 -3.3 -2.2 0.1 -2.8 0.4 -2.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 0.7 0.7 -0.8 -0.8 -0.3 0.7 -0.6 -0.2 0.0
Back pain experienced in last month 1.0 1.4 3.5 -1.0 1.7 1.9 0.8 -0.8 1.2 -0.9 0.5
Mineral and other dietary supplements 0.2 0.2 0.8 -0.2 0.7 0.3 0.9 -0.1 0.6 -0.2 0.3
Breast cancer (self-reported) 0.2 0.2 1.0 1.0 -0.1 -0.5 -0.1 0.5 -0.2 0.4 -0.1
Asthma (self-reported) 0.4 0.7 1.9 -0.2 0.5 0.6 0.9 1.4 0.8 1.0 0.8
Osteoporosis (self-reported) 0.3 0.4 1.2 -1.0 -0.0 0.7 -0.0 -0.3 0.0 -1.1 -0.4
Osteoarthritis (self-reported) 0.5 0.6 1.5 -0.3 0.3 0.2 0.9 1.2 0.8 0.6 1.2
Medication: Aspirin 1.5 1.9 5.0 0.5 2.2 1.2 1.5 0.4 1.6 0.9 1.7
Medication: Gliclazide 1.8 2.0 4.6 -2.1 1.5 1.9 1.0 -0.7 1.7 -0.5 1.0
Illnesses of father: None of the above (group 1) 0.1 0.1 0.4 -0.4 -0.3 -0.6 -0.1 -0.4 -0.2 -0.2 -0.4
Smoking status: Current 3.1 4.9 8.0 2.3 -1.9 -1.8 -2.5 -1.7 -2.8 -1.7 -2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.6 5.5 10.1 1.5 -3.2 -2.7 -3.0 -0.7 -2.9 -0.7 -2.4
Whole body water mass 0.5 3.1 5.3 1.7 -1.6 -1.6 -2.1 -1.5 -2.2 -0.3 -2.3
Leg predicted mass (right) 0.4 2.3 4.6 1.2 -1.3 -1.2 -1.9 -1.7 -1.8 -0.4 -2.2
Arm fat mass (left) 0.1 0.6 1.3 0.7 0.5 0.6 -0.6 -0.9 -0.4 -1.1 -1.0
Number of self-reported non-cancer illnesses 6.9 11.9 20.3 -2.8 3.9 3.0 4.1 2.4 4.5 1.6 4.2
Average weekly champagne plus white wine intake 0.3 0.3 0.9 0.5 -0.1 -0.3 0.2 1.0 0.2 0.9 0.8
Miserableness 2.7 4.6 10.6 -3.2 2.4 3.3 1.2 -1.1 2.0 -1.7 0.8
Guilty feelings 0.7 1.1 2.1 0.3 -1.4 -0.7 -1.4 -0.7 -1.3 -0.5 -1.3
Wears glasses or contact lenses 1.2 1.3 2.6 -1.3 1.4 1.6 1.1 0.3 1.5 -0.3 0.9
Ever taken oral contraceptive pill 0.8 0.9 1.6 -1.1 1.1 1.3 1.1 -0.1 1.0 -0.9 0.6
Hearing aid user 0.9 1.1 2.5 0.1 0.5 -0.1 0.8 1.3 0.9 1.5 1.6
Mother’s age at death 0.1 0.1 0.3 -0.3 -0.1 -0.2 -0.1 0.5 -0.3 -0.5 -0.2
Financial situation satisfaction 4.1 5.1 8.8 2.3 -2.4 -2.7 -2.8 -0.1 -3.0 -1.2 -2.2
Tinnitus: Yes, now most or all of the time 0.3 0.3 0.8 -0.6 0.5 0.6 0.5 -0.3 0.5 -0.9 0.5
Commuting to job workplace: Public transport 0.9 1.1 1.6 -0.6 1.3 1.2 1.1 1.0 1.2 0.3 1.1
Eye problems/disorders: Glaucoma 2.4 2.8 6.8 0.3 -0.8 0.3 -2.1 -1.3 -1.7 -2.6 -2.4
Medication: Blood pressure 2.8 5.3 10.1 -1.5 3.2 3.0 2.5 0.5 2.9 -0.7 2.4
Pain type(s) experienced in last month: Hip pain 1.4 1.8 4.1 -1.1 2.0 1.9 1.1 -0.1 1.6 -0.4 1.0
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.7 0.9 -0.5 -0.5 -0.3 0.5 -0.3 0.7 0.3
High cholesterol (Self-reported) 3.0 5.3 11.9 -2.0 3.0 3.5 2.3 -1.0 2.8 -0.1 1.8
Medication: Bendroflumethiazide 0.6 0.9 2.2 0.2 1.0 0.8 1.5 0.8 1.2 -0.1 1.3
Medication: Paracetamol 0.6 0.9 3.4 -0.1 -0.2 -0.8 -0.1 1.9 0.3 1.2 1.1
Medication: Lisinopril 1.8 2.3 4.1 -1.4 1.6 1.1 2.0 0.8 1.9 1.1 1.7
Medication: Atorvastatin 0.7 0.9 2.0 -1.1 1.0 1.4 -0.1 -1.3 0.5 -0.8 -0.2
Illnesses of father: High blood pressure 0.2 0.2 0.5 -0.1 -0.4 0.1 -0.5 -0.6 -0.4 -0.7 -0.2
Alcohol drinker status: Never 0.1 0.1 0.3 0.4 0.5 -0.3 -0.5 -0.1 -0.0 0.1 -0.1
Ever smoked 2.5 4.4 7.4 1.9 -2.2 -2.0 -2.6 -1.2 -2.7 -0.6 -2.6
Basal metabolic rate 0.5 3.0 5.3 1.7 -1.5 -1.4 -2.1 -1.4 -2.1 -0.6 -2.3
Leg fat percentage (left) 0.4 1.3 4.0 0.4 2.0 1.4 1.2 0.6 1.3 -0.6 0.8
Arm fat-free mass (left) 0.7 3.6 6.2 2.0 -1.5 -1.5 -2.4 -1.6 -2.3 -0.6 -2.5
Number of operations (self-reported) 0.8 1.1 3.2 1.7 -0.6 -1.3 0.0 1.8 -0.4 0.5 0.6
Average weekly beer plus cider intake 1.2 1.7 4.2 -0.3 -0.5 0.7 -1.3 -1.8 -1.0 -2.0 -1.6
Irritability 2.3 4.0 8.3 -2.4 2.6 2.9 1.8 -1.0 2.3 -0.3 1.1
Risk taking 0.1 0.1 0.8 -0.0 -0.4 -0.1 -0.0 0.9 0.0 0.3 0.2
Ever had prostate specific antigen (PSA) test 1.2 1.4 5.0 0.5 -0.5 -1.0 0.2 2.2 0.2 2.0 0.9
Fractured/broken bones in last 5 years 0.2 0.2 0.7 -0.3 0.4 0.5 0.5 0.2 0.4 -0.9 0.1
Age started oral contraceptive pill 0.7 0.8 2.2 -0.9 0.6 1.3 -0.1 -1.2 0.4 -1.5 -0.3
Diastolic blood pressure, automated reading 0.4 1.2 3.2 -0.7 1.8 1.8 0.4 -1.1 1.0 -0.9 0.0
Ever depressed for a whole week 0.5 0.6 1.3 -0.8 1.0 1.1 0.1 -0.1 0.6 -1.1 0.0
Unable to work because of sickness or disability 0.4 0.5 0.9 -0.9 0.6 1.0 0.5 -0.2 0.9 0.4 0.7
Commuting to job workplace: Cycle 1.0 1.3 2.6 -1.3 1.2 1.6 1.1 -0.8 1.2 -0.7 0.6
Myopia 1.9 2.8 5.0 -2.2 1.7 2.2 2.1 0.2 2.0 -0.2 1.0
Vascular/heart problems diagnosed by doctor 7.0 19.1 33.9 3.7 -5.8 -5.0 -5.2 -1.1 -5.6 -0.8 -4.5
Cholesterol lowering medication 3.6 5.4 9.8 -2.2 3.1 3.1 2.4 -0.8 2.8 -0.7 2.1
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 2.0 -0.4 1.4 1.0 1.2 0.4 1.2 1.1 0.9
Pain experienced in last month 0.9 1.5 3.9 0.6 -1.2 -2.0 -0.6 1.7 -0.6 1.7 0.2
Supplements: Calcium 0.4 0.4 1.1 -1.1 -0.6 0.3 -0.6 -1.0 -0.1 -0.7 -0.4
Basal cell carcinoma (self-reported) 1.1 1.4 7.4 0.0 0.1 -0.6 1.3 2.7 0.4 0.5 1.0
Heart attack/myocardial infarction (self-reported) 3.0 3.8 8.1 -1.2 2.9 2.1 2.3 0.3 2.5 0.1 2.2
Deep venous thrombosis (DVT) (self-reported) 2.1 2.6 6.2 -1.4 2.5 2.5 1.2 -0.8 2.0 0.3 0.9
Heart disease (siblings) 0.8 1.0 2.6 -0.1 1.6 1.4 0.9 -0.7 1.1 0.6 0.8
Alcohol drinker status: Previous 0.5 0.5 1.3 -0.6 1.1 1.2 0.5 -0.2 0.8 0.3 0.5
Pack years of smoking 0.9 1.3 2.4 -1.5 1.5 1.4 0.9 -0.0 1.4 -0.3 0.9
Impedance of whole body 0.2 1.0 2.7 0.3 -1.6 -1.3 -0.1 1.4 -0.6 0.9 0.4
Leg fat mass (left) 0.1 0.5 1.6 0.5 1.3 1.0 0.2 -0.2 0.4 -0.8 -0.2
Arm predicted mass (left) 0.7 3.6 6.4 2.0 -1.5 -1.5 -2.4 -1.7 -2.3 -0.5 -2.5