TWAS hub - CHKB-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1180	0.0410	5.7e-04	0.091	NA	0.049	NA	0.079	7.2e-08	NA	7.5e-05	NA	5.0e-07
2	GTEx	Adipose Visceral Omentum	0.1490	0.0500	6.0e-04	0.012	NA	0.016	NA	0.006	7.4e-02	NA	4.8e-02	NA	1.5e-01
3	GTEx	Brain Putamen basal ganglia	0.4410	0.1740	9.3e-03	0.010	NA	0.056	NA	0.074	1.8e-01	NA	1.9e-02	NA	8.1e-03
4	GTEx	Breast Mammary Tissue	0.1020	0.0420	4.5e-03	0.102	NA	0.030	NA	0.047	6.3e-06	NA	1.1e-02	NA	2.0e-03
5	GTEx	Breast Mammary Tissue (Male)	0.0701	0.0775	2.3e-01	-0.013	NA	-0.013	NA	-0.006	8.6e-01	NA	9.1e-01	NA	4.7e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1012	0.0595	4.7e-02	0.051	NA	0.007	NA	0.050	1.3e-02	NA	2.0e-01	NA	1.3e-02
7	GTEx	Cells Transformed fibroblasts	0.2020	0.0490	3.8e-07	0.114	NA	0.144	NA	0.147	7.5e-09	NA	6.5e-11	NA	3.6e-11
8	GTEx	Esophagus Mucosa	0.2060	0.0520	2.5e-07	0.185	NA	0.177	NA	0.179	1.8e-12	NA	6.4e-12	NA	4.3e-12
9	GTEx	Heart Atrial Appendage	0.1310	0.0560	8.8e-03	0.001	NA	0.036	NA	0.015	2.8e-01	NA	9.8e-03	NA	6.7e-02
10	GTEx	Nerve Tibial	0.1503	0.0614	3.1e-03	0.019	NA	0.011	NA	0.020	1.7e-02	NA	4.9e-02	NA	1.4e-02
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1740	0.0760	4.1e-03	0.100	NA	0.065	NA	0.084	4.1e-06	NA	1.9e-04	NA	2.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood Red Count	12.2	117.8	243.4	12.1	5.7	-0.2	12.0	15.6	2.7	12.3	12.9	9.6	13.4	11.5
Mother’s age at death	4.4	5.5	10.8	-2.8	-1.5	-0.4	-2.9	-0.8	-2.1	-3.3	-3.1	-2.0	-1.4	-3.3
Ever highly irritable/argumentative for 2 days	3.9	4.6	12.7	1.7	3.1	3.0	1.9	0.5	3.6	1.6	1.8	0.5	2.0	1.6
Health satisfaction	3.4	4.4	12.8	2.5	1.9	1.3	2.5	0.5	0.8	2.1	2.2	1.0	3.6	2.6
Angina (self-reported)	3.1	4.0	7.5	-2.7	-2.5	0.8	-2.7	-0.4	-0.1	-2.6	-2.4	-2.1	-0.7	-2.4
Medication: Bendroflumethiazide	3.1	4.8	9.4	-2.3	-1.5	0.3	-2.4	-1.9	0.2	-3.1	-2.9	-2.6	-2.3	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.8	9.3	2.1	3.1	1.1	2.1	1.8	2.5	1.9	2.3	0.4	1.0	1.9
Supplements: Vitamin C	3.0	3.5	7.4	2.1	0.7	2.7	2.1	0.8	1.5	1.6	1.7	1.3	2.5	2.3
Angina	2.8	3.7	6.8	-2.6	-2.4	0.7	-2.6	-0.3	-0.2	-2.5	-2.4	-2.0	-0.6	-2.2
Maternal smoking around birth	2.8	4.0	7.3	2.1	1.1	2.0	2.2	0.1	2.0	2.2	2.0	2.7	2.2	2.2
Risk taking	2.8	4.1	7.1	2.1	2.0	0.9	2.2	1.7	1.6	2.7	2.6	2.4	1.8	1.7
Supplements: Zinc	2.7	2.9	4.7	1.9	0.7	2.1	2.0	1.5	2.0	2.2	1.9	1.0	1.1	1.7
Diabetes (father)	2.7	3.3	5.8	2.1	1.5	0.9	2.2	1.1	-0.0	2.2	1.9	1.6	2.4	2.4
Illnesses of mother	2.7	3.3	11.5	1.7	3.4	1.2	1.7	0.9	1.3	2.1	2.1	1.4	1.5	1.5
Diverticular disease/diverticulitis (self-reported)	2.5	3.0	7.1	1.9	1.7	0.3	1.9	1.8	-0.0	2.4	2.7	1.3	1.2	1.9
Severe depression (siblings)	2.4	2.7	5.5	-2.1	-0.2	-0.2	-2.1	-1.3	-0.9	-1.9	-2.0	-2.3	-0.6	-2.4
Supplements: Glucosamine	2.4	3.1	7.0	1.7	1.6	2.2	1.8	0.6	2.6	1.7	1.6	1.2	1.6	2.0
Had menopause	2.2	2.7	5.9	-1.8	-1.7	-2.4	-1.9	-0.9	-1.1	-1.8	-1.5	-1.7	-0.8	-1.7
Leg pain on walking	2.2	2.8	6.3	1.8	0.4	0.6	1.9	-0.4	0.8	2.2	2.1	1.8	2.5	1.9
Miserableness	2.2	3.8	5.7	2.2	2.1	0.7	2.2	1.6	0.8	2.2	2.0	2.2	2.2	2.4
Alzheimer’s Disease (in father)	2.1	2.2	4.7	-1.7	-0.5	-0.4	-1.7	-0.8	-0.3	-1.8	-1.7	-1.5	-2.2	-2.1
Frequency of depressed mood in last 2 weeks	2.1	2.9	6.0	1.9	2.4	1.4	1.9	1.8	1.1	1.5	1.1	1.2	1.7	2.1
Length of working week for main job	2.1	2.3	4.3	2.0	1.0	1.1	2.1	0.5	0.9	1.8	1.7	0.6	1.8	2.1
Sensitivity / hurt feelings	2.0	3.4	6.3	-2.1	0.1	-2.5	-2.1	-0.6	-0.0	-1.9	-1.5	-2.3	-2.5	-2.2
Medication for hormone replacement therapy	2.0	2.2	5.1	1.4	2.3	2.0	1.5	0.7	1.4	1.6	1.7	0.2	0.6	1.6
High blood pressure (mother)	1.9	2.6	4.7	-2.0	-0.6	-0.4	-1.9	-1.2	-0.9	-1.9	-1.5	-1.9	-2.0	-2.2
Family relationship satisfaction	1.9	2.3	6.4	1.6	1.0	1.6	1.6	0.4	0.9	1.6	1.8	1.0	2.5	1.5
Illnesses of father: Heart disease	1.9	2.6	8.1	-1.6	-2.8	0.4	-1.6	-2.0	-0.2	-2.0	-2.1	-1.1	-0.8	-1.2
Commuting to job workplace: Walk	1.9	2.1	9.1	1.1	-0.1	0.4	1.1	2.3	1.5	0.9	1.4	3.0	0.4	0.8
Allergy or Eczema	1.8	4.6	10.7	2.5	2.6	0.2	2.5	3.3	0.7	2.2	2.4	0.9	1.5	2.6
Hypothyroidism (self reported)	1.8	4.2	14.8	2.1	1.4	1.5	2.3	1.5	1.9	1.9	1.4	0.6	3.8	2.4
Pack years adult smoking proportion	1.8	2.8	5.5	1.7	0.2	2.2	1.8	0.9	2.3	1.7	1.8	2.4	0.6	1.5
Worrier / anxious feelings	1.7	3.3	5.3	-2.0	0.2	-0.9	-2.1	1.3	-1.3	-2.3	-2.3	-2.0	-2.1	-2.0
Osteoporosis (self-reported)	1.7	2.1	5.0	-1.2	-0.7	-2.2	-1.2	-1.9	-1.5	-1.6	-1.9	-0.9	-1.0	-0.9
Number of incorrect matches in round	1.6	2.7	7.3	-2.2	-0.8	-1.1	-2.1	0.1	-0.6	-1.4	-1.6	-1.6	-2.7	-1.8
Fasting Glucose	1.5	1.8	4.1	1.0	1.5	1.3	1.2	1.3	2.0	1.5	1.9	0.9	0.4	0.7
Happiness	1.5	1.9	3.4	1.5	1.9	0.7	1.5	0.8	0.5	1.4	1.6	1.2	1.8	1.3
Wears glasses or contact lenses	1.5	1.7	2.8	-1.6	-1.2	1.2	-1.6	0.1	0.9	-1.5	-1.5	-1.5	-0.2	-1.7
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.7	1.7	1.2	1.4	1.8	0.5	0.9	1.5	1.6	0.8	1.0	1.9
Townsend deprivation index at recruitment	1.4	1.9	4.3	1.9	0.6	0.7	1.9	0.5	0.7	1.4	1.4	1.8	1.1	2.1
Hayfever, allergic rhinitis or eczema	1.4	3.0	5.3	2.1	2.3	0.7	2.0	2.2	0.7	1.7	1.8	0.8	1.4	2.1
Number of live births	1.4	2.0	7.3	-0.7	-1.0	-1.4	-0.9	-2.7	-1.9	-0.9	-0.8	-0.3	-2.2	-0.7
Medication: Cholesterol lowering	1.4	2.2	4.7	-1.8	-1.4	0.2	-1.8	-1.1	0.0	-2.2	-2.0	-1.2	-1.4	-1.4
Gout (self-reported)	1.4	1.9	6.2	1.6	0.8	0.9	1.6	0.7	0.6	1.6	1.4	0.6	2.5	1.5
Shortness of breath walking on level ground	1.4	1.6	5.2	1.1	1.2	1.3	1.2	-0.2	1.0	1.6	1.1	0.5	2.3	1.4
Hypertension (Self-reported)	1.4	3.9	6.9	-2.2	-2.6	-0.0	-2.2	-1.1	0.1	-2.4	-2.3	-2.6	-1.3	-2.3
Financial situation satisfaction	1.4	1.8	4.4	1.1	2.0	0.9	1.2	0.0	0.6	1.5	1.4	1.4	2.1	1.1
HbA1C	1.3	1.5	3.7	1.2	1.0	0.2	1.2	1.6	-0.1	1.5	1.3	1.9	1.0	1.2
Had other major operations	1.3	1.6	3.9	1.4	2.0	-0.8	1.4	1.6	0.8	1.4	1.5	0.3	0.8	1.3
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	3.2	1.6	0.8	-0.2	1.5	1.3	-0.1	1.6	1.8	1.5	1.5	1.5
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	3.6	1.0	1.5	1.9	1.2	1.7	0.9	1.5	1.7	1.6	1.4	1.3
Lung cancer (father)	1.3	1.5	5.0	1.5	2.2	-0.8	1.4	0.2	0.4	1.4	1.4	-0.4	0.9	1.1
Medication: Allopurinol	1.3	1.7	3.5	1.5	-0.1	1.2	1.5	0.2	0.3	1.6	1.5	1.4	1.9	1.5
Overall health rating	1.3	2.7	7.7	1.7	1.3	2.8	1.7	0.2	0.4	1.7	1.5	0.5	1.8	2.5
Unable to work because of sickness or disability	1.3	1.7	6.3	0.6	0.9	2.5	0.8	0.4	2.3	0.7	0.8	1.4	0.6	1.3
Vascular/heart problems diagnosed by doctor	1.3	3.6	7.6	2.1	2.7	-0.5	2.1	0.8	0.1	2.4	2.2	2.5	1.2	2.0
Fed-up feelings	1.2	2.2	5.6	1.7	0.2	-0.2	1.6	0.5	0.0	1.4	1.2	2.2	2.4	2.1
Qualifications: CSEs or equivalent	1.2	1.5	4.7	1.2	1.2	1.3	1.3	2.2	0.8	1.2	0.6	1.0	0.2	1.5
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.5	1.4	1.9	0.4	1.6	1.9	1.5	1.2	1.1	1.2	0.7	1.5
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	5.1	0.5	2.3	2.0	0.5	1.2	2.2	0.2	0.2	0.3	0.7	0.5
Financial difficulties in last 2 years	1.2	1.6	3.9	1.7	1.6	0.5	1.7	-0.0	0.1	1.5	1.4	0.8	0.8	2.0
Medication: Blood pressure	1.2	2.2	4.5	-1.6	-1.9	-0.0	-1.6	-1.5	-0.2	-1.8	-1.6	-2.1	-0.2	-1.7
Primary Biliary Cirrhosis	1.1	1.5	4.6	1.3	0.8	-0.6	1.1	1.1	-1.3	1.2	1.5	0.6	2.1	1.0
Medication: Metformin	1.1	1.5	10.3	-0.9	-3.2	0.9	-0.9	0.0	-1.2	-0.8	-0.9	0.9	-0.0	-0.7
Heart attack	1.1	1.4	4.1	-1.4	-2.0	-0.7	-1.4	-0.4	-0.3	-1.4	-1.5	-0.9	-0.7	-0.9
Tense / ‘highly strung’	1.1	1.8	5.6	1.5	0.9	0.5	1.4	2.4	0.4	1.4	1.7	1.1	1.3	1.1
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	10.2	1.4	0.6	0.9	1.5	0.4	1.7	0.9	0.6	-0.4	3.2	1.8
Friendships satisfaction	1.1	1.4	6.7	1.1	0.1	0.9	1.0	-1.2	0.3	1.1	1.2	0.7	2.6	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.2	4.5	-1.5	-2.0	0.3	-1.6	-0.9	-1.9	-0.8	-1.3	-0.7	-2.1	-2.0
Cardiovascular Disease	1.0	3.4	7.5	-1.9	-2.7	1.0	-1.9	-1.0	-0.8	-2.5	-2.4	-2.1	-1.3	-1.6
Hearing difficulty/problems: Yes	1.0	1.5	7.7	0.6	1.9	1.0	0.7	0.1	2.8	1.0	1.4	0.0	0.1	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.0	1.3	1.6	-0.0	1.2	0.9	-0.3	0.8	0.5	1.3	1.7	1.6
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.9	1.2	0.9	-0.5	1.3	0.2	1.7	1.2	1.4	1.5	0.1	1.1
Migraine (self-reported)	1.0	1.2	2.4	-1.2	0.7	-0.3	-1.3	1.4	-0.3	-1.0	-0.9	-1.3	-1.6	-1.1
Mean time to correctly identify matches	1.0	1.8	4.3	-1.1	-2.1	-1.2	-1.2	0.9	-1.7	-1.3	-1.4	-1.8	0.5	-0.9
Commuting to job workplace: Car/motor vehicle	1.0	1.1	5.3	-0.8	-0.4	-0.4	-0.8	-2.2	-0.1	-0.5	-0.3	-2.3	-0.4	-0.7
Qualifications: nursing, teaching	1.0	1.6	3.9	-1.2	-0.1	1.8	-1.2	-0.2	0.1	-1.3	-1.3	-2.0	-1.2	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.9	-0.8	-0.7	-1.5	-0.9	0.7	-0.9	-1.0	-1.3	0.1	-1.7	-1.1
Medication: Gliclazide	1.0	1.2	5.4	-1.0	-2.3	-0.1	-0.9	1.1	-0.5	-1.0	-1.4	0.6	0.2	-0.9
Myopia	1.0	1.5	3.1	-1.7	-0.4	1.8	-1.6	-1.1	0.0	-1.4	-1.0	0.0	-1.4	-1.4
Pain experienced in last month	1.0	1.7	3.5	-1.1	-1.8	-1.4	-1.3	0.0	-1.4	-1.4	-1.9	0.1	-0.6	-1.5
Heart attack/myocardial infarction (self-reported)	1.0	1.3	5.3	-1.2	-2.3	-0.5	-1.3	-0.5	-0.4	-1.3	-1.5	-0.9	-0.4	-0.7
Pack years of smoking	1.0	1.4	3.2	1.1	-0.2	1.8	1.2	0.1	1.8	1.1	1.1	1.7	0.3	1.0
Alzheimer’s Disease (including proxy)	0.9	1.3	4.1	-0.9	-1.1	0.1	-1.0	-0.5	-0.3	-1.8	-2.0	-1.1	-1.6	-0.7
Ovarian Cancer	0.9	1.2	4.2	0.8	0.5	1.0	0.8	1.4	-0.2	1.2	1.3	2.0	0.8	0.5
Lupus	0.9	1.3	3.8	1.4	0.8	-0.1	1.4	0.9	0.9	0.9	1.0	-0.3	2.0	1.5
Number of treatments/medications taken	0.9	1.5	3.7	-1.4	-1.5	0.6	-1.4	-0.4	0.4	-1.6	-1.5	-1.9	-0.8	-0.8
Diabetes (mother)	0.9	1.2	4.5	-0.8	-2.1	-1.5	-0.8	-0.2	-1.0	-0.9	-1.0	-1.3	0.1	-0.7
Age when periods started (menarche)	0.9	2.2	5.0	1.7	2.2	-0.1	1.7	2.0	1.3	1.2	1.2	0.0	1.4	1.7
High blood pressure	0.9	2.5	5.6	-1.7	-2.0	0.3	-1.6	-0.7	0.5	-1.9	-1.8	-2.4	-1.2	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	5.4	0.0	-2.3	-0.6	-0.0	-1.4	-1.1	0.0	-0.2	1.4	0.4	0.3
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.2	-0.9	-1.5	-0.5	-0.9	-1.5	-0.4	-1.3	-1.4	0.6	-0.4	-0.7
Medication: Blood pressure	0.9	1.6	3.0	-1.2	-0.7	0.6	-1.1	-1.2	1.5	-1.4	-1.1	-1.7	-1.4	-1.2
Irritable Bowel Disease (IBD)	0.8	1.8	3.2	1.5	1.5	0.5	1.4	1.0	0.0	1.5	1.7	1.3	1.8	1.5
Prostate Cancer	0.8	1.2	2.0	-1.3	-1.0	-0.2	-1.3	1.1	-0.6	-1.4	-1.4	-1.0	-0.5	-1.1
Neuroticism (2016)	0.8	1.1	2.4	-1.3	0.1	-0.8	-1.3	-0.2	-0.0	-1.3	-1.6	-1.3	-1.0	-1.1
Chronotype (morning person)	0.8	1.8	10.4	1.3	0.3	-3.2	1.1	1.2	-1.7	0.5	-0.0	0.5	0.2	1.3
Vitamin and mineral supplements	0.8	1.1	6.1	-0.8	-0.3	-2.5	-0.8	1.4	-1.0	-0.4	-0.4	-1.0	-0.3	-1.0
Allergy	0.8	1.7	3.2	-1.6	-1.6	0.3	-1.5	-1.6	-0.1	-1.3	-1.5	-0.2	-1.4	-1.8
Diabetes (self-reported)	0.8	1.2	3.4	1.0	-1.0	1.1	1.0	1.1	-0.2	1.0	1.1	1.8	1.1	1.1
Father’s age at death	0.8	1.1	2.8	0.9	0.4	-0.5	1.0	1.4	0.9	1.3	1.7	1.3	1.1	0.4
Birth weight of first child	0.8	1.5	4.9	0.4	2.2	-1.6	0.5	1.7	0.7	0.9	1.5	1.3	-0.9	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.8	1.1	0.9	0.7	1.2	0.1	1.3	1.3	1.2	1.1	-0.0	0.9
Medication: Aspirin	0.8	1.0	3.4	-0.8	-1.8	1.0	-0.8	-0.8	1.1	-1.3	-1.3	-0.1	-0.1	-0.6
Illnesses of siblings: Diabetes	0.8	0.9	3.3	0.8	-0.5	0.1	0.9	1.8	0.7	0.8	0.9	1.0	1.1	1.0
Breast cancer (self-reported)	0.8	0.9	2.9	-0.9	0.6	-1.7	-0.9	-0.6	-0.2	-0.3	-0.2	-1.7	-0.3	-1.3
Eye problems/disorders: Glaucoma	0.8	0.9	4.6	0.1	-0.8	-1.4	-0.0	2.1	-1.6	-0.2	-0.4	-0.2	0.4	0.2
Ulcerative Colitis (UC)	0.7	1.4	2.8	1.0	1.1	-0.1	1.0	1.7	-0.6	1.2	1.5	1.7	0.7	1.2
Mean Putamen Volume	0.7	0.8	2.7	0.7	1.6	-0.2	0.7	1.5	0.2	1.1	1.0	0.1	0.3	0.8
Blood Platelet Count	0.7	8.1	27.0	1.1	5.2	3.2	1.3	0.8	4.6	1.2	0.5	2.2	4.4	1.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.7	0.8	1.4	1.6	0.9	0.1	1.1	0.9	0.8	0.7	-0.2	0.8
Systolic blood pressure, automated reading	0.7	2.0	8.6	-1.2	-2.9	-1.0	-1.3	0.0	-1.4	-1.1	-1.5	-1.4	-0.4	-1.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	2.1	1.0	-0.0	-0.7	1.0	0.6	-0.1	1.5	1.3	0.9	1.2	0.8
Multivitamins +/- minerals	0.7	0.8	4.9	0.2	0.1	2.2	0.2	-1.7	0.7	0.1	0.0	0.8	-0.6	0.3
Qualifications: None of the above	0.7	1.5	3.9	0.6	-1.9	-1.5	0.4	-1.3	-2.0	-0.2	-0.3	1.0	1.3	1.4
Medication: Ramipril	0.7	0.9	4.3	-0.9	-2.1	0.5	-0.9	-0.5	-0.1	-1.1	-1.3	-0.3	-0.4	-0.5
Alcohol intake versus 10 years previously	0.7	1.1	4.3	0.7	0.2	2.1	0.8	-1.5	0.6	0.7	0.4	0.4	1.4	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.0	1.2	1.3	0.4	1.2	1.4	0.3	1.4	1.4	0.8	0.6	0.9
Blood clot in the leg (DVT)	0.7	0.9	2.0	0.8	0.6	-0.4	0.9	-1.0	1.4	0.8	1.0	0.8	1.1	1.2
High blood pressure (siblings)	0.7	0.9	3.3	-1.0	-1.8	-0.8	-1.0	-0.5	-0.3	-1.1	-0.8	-1.3	-0.1	-0.8
Worry too long after embarrassment	0.7	1.2	2.1	-1.2	0.3	1.1	-1.4	1.2	-0.7	-1.5	-1.4	-1.0	-0.6	-1.0
Eye problems/disorders: None of the above	0.7	0.8	4.0	-0.9	-0.6	0.9	-0.9	-2.0	0.1	-0.9	-0.8	-0.2	-0.5	-0.9
Emphysema/chronic bronchitis	0.7	0.8	2.4	0.4	1.1	-1.2	0.5	-0.3	1.4	0.3	0.4	-1.6	-0.7	0.3
Medication: Omeprazole	0.7	0.9	3.7	0.5	1.9	1.2	0.4	-1.3	0.6	0.2	0.1	-0.9	0.7	0.7
Heart disease (mother)	0.7	0.8	2.1	-1.0	-1.5	-0.9	-1.0	0.1	-0.8	-0.6	-0.7	-1.2	-0.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.3	-1.0	0.8	-0.4	-1.0	0.9	0.7	-1.1	-0.9	-1.0	-1.1	-0.7
Back pain experienced in last month	0.7	1.1	2.7	0.8	1.3	0.9	0.9	-1.6	0.4	1.2	1.4	0.1	-0.5	1.3
Medication: Aspirin	0.7	0.9	2.6	-0.7	-1.6	0.6	-0.7	-0.9	0.8	-1.2	-1.3	-0.5	-0.3	-0.5
Number of operations (self-reported)	0.7	1.1	4.5	0.1	1.6	-2.1	0.2	0.7	0.9	0.5	0.8	-0.5	-1.6	-0.0
Basal cell carcinoma (self-reported)	0.7	0.8	2.3	-1.1	0.1	-1.5	-1.0	-0.2	0.2	-0.3	0.0	-1.1	-1.2	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.3	0.7	0.5	-0.6	0.9	-0.9	1.1	0.8	1.0	1.0	1.1	1.1
Reaction Time	0.6	1.1	4.4	-0.8	-1.1	-1.1	-0.9	0.7	-2.1	-1.0	-1.0	-1.2	0.2	-0.4
HDL Cholesterol	0.6	1.0	1.8	1.0	1.1	1.1	1.1	-0.9	1.0	0.9	0.7	0.3	1.3	1.1
LDL Cholesterol	0.6	1.0	3.3	0.5	0.8	1.8	0.6	-0.1	1.5	0.4	0.1	0.4	1.6	0.8
Hand grip strength (left)	0.6	1.6	3.3	1.7	1.0	0.4	1.7	-0.1	0.2	1.8	1.7	0.1	1.2	1.6
Ever had hysterectomy (womb removed)	0.6	0.7	4.5	-0.2	-1.1	-2.1	-0.2	-0.8	-0.8	-0.2	-0.1	0.7	-0.5	-0.5
Medication: Co-codamol	0.6	0.7	2.0	0.9	0.9	0.1	1.1	0.4	0.2	1.4	1.4	0.0	-0.4	1.0
Chronic bronchitis/emphysema (father)	0.6	0.7	2.0	-1.0	0.4	-0.4	-1.0	-1.4	-0.5	-0.8	-1.0	-0.4	-0.4	-1.0
Hair/balding pattern: Pattern 2	0.6	0.7	4.1	1.0	2.0	0.4	0.9	0.3	-0.2	0.6	0.1	0.5	0.3	1.2
Exposure to tobacco smoke at home	0.6	0.7	2.7	-0.6	0.2	-1.6	-0.5	0.1	-1.1	-0.2	0.0	-0.4	-1.5	-0.7
Pulse wave reflection index	0.6	0.7	1.4	-0.9	-1.2	-1.2	-0.9	0.9	-0.4	-1.0	-0.8	-0.7	0.5	-0.8
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.6	-0.8	1.0	1.9	-0.8	-0.8	-0.1	-0.3	-0.2	-1.4	-0.7	-1.2
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	1.5	1.2	1.1	-0.4	1.1	1.0	-0.4	1.1	1.0	1.0	1.2	1.0
Birth weight	0.6	1.3	4.9	0.6	0.2	-2.2	0.7	-0.1	-0.1	1.5	1.8	1.4	-0.7	-0.1
Number of children fathered	0.6	0.6	1.9	-0.6	-0.8	-0.6	-0.6	-0.0	-0.6	-0.7	-1.4	-0.6	-1.2	-0.7
Age at last live birth	0.6	0.9	2.1	-1.1	-0.6	-0.5	-1.2	-0.3	0.5	-1.4	-1.1	-0.3	-0.7	-1.5
Diabetes diagnosed by doctor	0.6	1.0	3.4	0.4	-1.8	1.0	0.5	1.1	-0.3	0.5	0.6	1.8	0.7	0.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.3	0.7	1.0	-1.0	0.7	0.2	-0.8	1.3	1.5	-0.2	-0.3	0.2
Commuting to job workplace: Cycle	0.6	0.7	4.2	0.4	0.7	-0.6	0.5	2.1	-0.1	0.8	1.0	0.3	-0.4	-0.0
Cholesterol lowering medication	0.6	0.9	3.3	1.0	0.0	0.4	1.0	0.2	0.0	1.0	1.1	0.3	1.8	1.3
Depression (Nagel 2018)	0.5	0.8	1.8	1.2	1.1	-0.1	1.2	0.7	-0.1	0.7	0.4	0.9	1.0	1.3
Age at First Birth	0.5	0.7	3.0	-0.7	-1.7	0.4	-0.9	0.1	-0.3	-1.4	-1.0	-0.3	-0.4	-0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.2	-0.8	-1.0	1.1	-0.8	0.0	-0.7	-0.7	-0.6	0.1	0.5	-1.0
Type 2 Diabetes (T2D) (2018)	0.5	1.0	4.8	-0.9	-2.2	0.6	-0.9	-0.1	-1.1	-1.0	-0.9	-0.2	-0.9	-0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.8	0.6	0.7	0.5	0.6	-1.3	0.5	0.7	0.6	-0.5	-0.6	0.7
Stomach or abdominal pain in last month	0.5	0.7	2.7	-0.2	0.8	0.8	-0.2	-1.6	0.5	-0.1	-0.3	-1.5	-0.8	-0.0
Past tobacco smoking	0.5	0.9	2.1	1.4	0.1	-0.2	1.3	-0.2	-0.2	1.3	1.4	0.5	1.0	1.2
Hearing difficulty/problems with background noise	0.5	0.9	3.5	-1.1	0.2	1.9	-1.0	-0.6	1.0	-0.3	-0.1	-1.0	-0.1	-1.2
Mouth/teeth dental problems	0.5	0.7	4.1	-0.2	-0.6	0.1	-0.3	2.0	-1.2	-0.2	-0.5	-0.9	1.0	-0.4
Medication: Simvastatin	0.5	0.8	1.3	-1.2	-0.9	0.5	-1.1	-1.1	-0.3	-1.2	-0.8	-0.6	-0.5	-1.0
Time employed in main current job	0.5	0.5	1.9	0.7	1.1	0.1	0.6	-0.3	0.3	-0.5	-0.7	-0.6	1.4	0.7
Prospective memory result	0.5	0.6	2.6	-0.8	0.1	-0.9	-0.8	-0.4	0.2	-0.7	-1.0	-0.3	-1.6	-0.7
Pulse wave Arterial Stiffness index	0.5	0.6	2.7	-0.6	-1.6	-1.4	-0.6	-0.1	-0.9	-0.3	-0.3	-0.1	0.4	-0.3
Hair/balding pattern: Pattern 4	0.5	1.2	5.5	-1.0	0.3	1.0	-0.7	0.7	2.3	-0.5	-0.0	-1.7	0.5	-1.1
Medication: Amlodipine	0.5	0.7	3.1	-0.7	-1.7	-0.1	-0.7	-1.1	-0.0	-0.5	-0.3	-0.9	-0.5	-0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.4	0.9	-0.6	-0.3	0.8	0.5	-0.1	1.0	0.9	1.0	0.6	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.1	-0.6	-1.5	0.0	-0.6	-0.1	0.8	-1.0	-0.9	-0.6	-0.9	-0.8
Medication: Seretide 50 evohaler	0.5	0.6	1.3	0.8	-0.3	1.1	0.7	-0.7	0.5	0.5	0.6	0.6	1.1	1.0
Number of full sisters	0.5	0.6	2.3	0.2	-1.5	-0.4	0.1	-1.5	-1.2	-0.0	-0.6	0.3	0.0	0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.8	0.3	1.3	-0.2	0.4	-1.7	1.1	0.6	0.3	1.4	-0.1	0.5
Smoking status: Current	0.5	0.8	1.9	-1.0	-0.6	-1.4	-1.0	-0.3	-0.4	-0.5	-0.6	1.2	-1.4	-0.9
Hearing aid user	0.5	0.5	1.6	0.7	1.0	0.1	0.7	1.3	0.6	0.5	0.4	-0.0	0.9	0.6
Fractured/broken bones in last 5 years	0.5	0.7	2.4	0.5	0.8	-0.6	0.6	0.8	1.5	0.6	0.5	1.3	-0.1	0.6
Heart disease (siblings)	0.5	0.6	1.9	0.1	-1.4	-1.3	0.1	-0.3	-0.9	-0.5	-1.2	-0.3	-0.7	0.5
Alcohol drinker status: Previous	0.5	0.6	2.2	-0.7	-0.2	-0.3	-0.8	-0.3	-1.5	-0.7	-0.7	-0.6	-1.0	-0.6
Schizophrenia (2018)	0.4	0.8	2.5	-0.8	0.4	1.4	-0.7	0.3	1.6	-0.9	-0.9	-0.9	1.1	-0.3
Worry (Nagel 2018)	0.4	0.9	3.4	-0.6	0.2	-1.1	-0.8	0.4	-1.8	-1.1	-1.2	-1.0	-0.5	-0.6
Alzheimer’s Disease (in mother)	0.4	0.5	1.2	0.3	-1.1	1.0	0.2	-0.0	-0.3	-0.8	-1.1	-0.2	0.2	0.9
Crohns Disease (2012)	0.4	0.7	2.6	-0.8	-0.2	-1.6	-0.8	0.7	0.2	-1.0	-0.7	-0.5	-0.6	-1.0
Schizophrenia (2014)	0.4	1.0	4.3	0.4	1.7	1.0	0.5	0.4	1.1	0.1	0.3	-0.1	2.1	0.8
Ulcerative Colitis	0.4	0.6	2.9	-0.1	-0.4	-0.2	-0.2	0.3	-1.7	0.3	0.8	1.3	0.8	0.3
Respiratory disease	0.4	1.0	5.0	0.6	0.4	0.3	0.7	2.2	0.9	0.8	1.4	0.4	-0.2	1.0
Lung FVC	0.4	1.8	8.0	-1.3	-2.8	-0.7	-1.4	0.0	-0.2	-1.3	-1.5	-0.9	-0.9	-1.6
Relative age voice broke	0.4	0.6	1.3	0.7	0.8	1.1	0.7	-0.3	-0.2	0.7	0.1	-0.7	1.1	0.9
Medication: Atenolol	0.4	0.4	2.3	0.3	-0.4	0.5	0.3	-0.6	1.0	-0.0	-0.2	-0.6	1.5	0.5
Medication: Levothyroxine sodium	0.4	0.7	3.1	0.6	0.4	-0.3	0.7	-0.9	0.6	0.2	-0.3	-0.8	1.7	1.3
Illnesses of siblings	0.4	0.6	2.9	0.5	1.7	0.7	0.5	-0.4	0.4	0.7	1.0	0.8	-0.3	0.0
Hip circumference	0.4	1.6	11.9	-0.4	-1.4	0.5	-0.3	-3.5	-0.9	-0.4	-0.5	-1.1	-0.7	0.1
Falls in the last year	0.4	0.5	1.8	-0.5	-0.9	1.3	-0.4	0.8	-0.4	0.1	0.6	1.0	-0.1	-0.4
Hair/balding pattern: Pattern 3	0.4	0.5	2.6	-0.7	0.1	0.1	-0.6	-0.7	0.9	-0.4	-0.1	-0.4	-1.6	-0.9
Mouth/teeth dental problems: Dentures	0.4	0.6	1.2	-1.0	-0.8	0.5	-0.8	-0.7	0.8	-1.0	-0.7	-0.5	-1.1	-0.6
Loud music exposure frequency	0.4	0.4	1.2	-0.6	0.2	1.1	-0.4	-0.4	1.0	-0.4	-0.6	-0.2	-0.9	-0.4
Headache pain in last month	0.4	0.7	4.7	-0.5	0.4	1.1	-0.4	2.2	1.0	-0.2	-0.1	-0.3	-0.8	-0.1
Pulse wave peak to peak time	0.4	0.5	2.6	0.4	1.6	1.2	0.4	-0.3	0.8	0.2	0.1	0.1	-0.5	0.1
Qualifications: College or University degree	0.4	1.3	3.3	-0.1	1.8	-0.4	0.1	1.8	1.8	0.2	0.8	-1.6	-0.3	-1.1
Medication for pain relief, constipation, heartburn	0.4	0.7	2.1	0.8	0.7	0.2	0.8	1.4	0.6	0.9	0.8	-0.3	1.3	0.2
Had major operations	0.4	0.4	1.8	0.1	-0.2	-0.1	0.3	0.3	1.2	0.7	1.3	0.1	-0.8	-0.3
Average weekly red wine intake	0.4	0.6	2.7	0.1	0.9	-1.3	0.1	0.3	-0.7	0.1	-0.2	-1.7	-0.7	0.2
Loneliness, isolation	0.4	0.6	2.9	0.4	-0.5	1.0	0.3	1.7	-0.5	0.3	-0.2	1.2	0.4	0.4
Ever had bowel cancer screening	0.4	0.5	2.1	-0.5	0.1	1.5	-0.5	-0.1	0.4	-0.7	-0.5	-0.8	0.1	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	3.5	0.4	-0.1	0.1	0.4	-1.9	0.0	0.4	0.3	-0.0	0.2	0.6
Asthma (self-reported)	0.4	0.8	3.9	0.6	0.1	0.6	0.5	2.0	0.3	0.8	1.2	1.1	-0.0	0.7
Osteoarthritis (self-reported)	0.4	0.5	2.4	0.6	0.4	-0.6	0.6	1.6	-0.2	0.4	0.1	0.5	0.1	1.0
Illnesses of father: None of the above (group 1)	0.4	0.5	0.9	0.9	0.9	-0.0	0.9	0.7	0.1	0.8	0.9	0.9	0.3	0.7
Ever taken oral contraceptive pill	0.4	0.4	1.4	0.5	0.2	0.9	0.5	1.2	0.3	0.8	0.4	-0.9	0.0	0.6
Commuting to job workplace: Public transport	0.4	0.4	1.9	-0.5	-1.4	-0.6	-0.5	-0.4	-0.6	-0.4	-0.6	0.8	0.4	-0.5
Illnesses of father: High blood pressure	0.4	0.5	1.4	0.6	0.9	0.9	0.6	1.2	0.5	0.4	0.4	-0.2	0.9	0.6
Alcohol drinker status: Never	0.4	0.5	3.5	-0.1	-0.3	0.9	-0.0	-1.9	-0.0	-0.4	-0.6	0.3	0.3	0.2
Ever smoked	0.4	0.7	1.7	-1.2	0.2	-0.8	-1.1	0.2	-0.1	-0.9	-0.8	0.1	-1.3	-0.9
Diastolic blood pressure, automated reading	0.4	1.3	6.3	-0.6	-2.5	-1.4	-0.6	-0.6	-1.5	-0.6	-1.0	-0.7	-0.6	-0.0
Ever depressed for a whole week	0.4	0.6	3.8	0.1	0.9	1.9	0.1	0.9	0.5	-0.1	-0.0	-0.0	0.5	0.1
Crohns Disease (2017)	0.3	0.7	2.9	0.9	1.0	0.3	0.9	0.1	0.3	0.5	0.6	-0.2	1.7	0.9
Triglycerides	0.3	0.5	1.7	-0.5	1.2	0.1	-0.6	-0.0	0.3	-0.1	-0.2	-1.3	-1.0	-0.4
Heel T-Score	0.3	2.2	8.6	-1.0	-2.9	-0.6	-1.1	0.7	0.5	-1.2	-0.6	-1.4	-2.3	-1.9
Waist Hip Ratio (WHR)	0.3	1.4	5.2	1.0	0.6	-0.0	1.0	-0.9	0.4	1.4	1.6	2.3	1.3	1.1
Lung FEV1/FVC ratio	0.3	1.6	4.4	-1.6	-0.8	1.2	-1.5	0.5	0.2	-1.0	-0.6	-0.9	-2.1	-1.9
Neuroticism	0.3	0.8	1.5	-1.1	-0.2	-0.4	-1.2	0.7	-0.6	-1.2	-1.2	-0.1	-1.1	-1.1
Average weekly spirits intake	0.3	0.4	1.6	0.2	-0.7	-1.1	0.1	-0.3	-1.3	0.4	0.3	-0.5	0.4	-0.2
Current tobacco smoking	0.3	0.5	3.2	-0.5	-0.2	-1.0	-0.5	0.2	0.0	0.0	-0.0	1.8	-1.0	-0.4
Average weekly fortified wine intake	0.3	0.3	1.0	0.6	0.8	-0.0	0.5	0.8	0.3	0.1	-0.1	-0.3	1.0	0.7
Taking other prescription medications	0.3	0.5	1.7	0.4	-1.0	0.4	0.5	0.8	0.6	0.0	-0.3	0.1	1.3	1.1
Serious illness, injury or assault to yourself	0.3	0.4	1.5	0.0	-0.1	-1.2	-0.0	-1.0	-0.0	-0.4	-0.5	-0.8	-0.4	0.6
Waist circumference	0.3	1.0	8.9	0.2	-0.8	0.5	0.2	-3.0	-0.6	0.4	0.5	-0.4	-0.0	0.6
Alcohol usually taken with meals	0.3	0.5	2.2	-0.6	0.7	-0.2	-0.4	-0.2	1.5	-0.0	0.4	-0.8	-0.6	-0.7
Nervous feelings	0.3	0.6	2.3	-0.1	0.3	-1.2	-0.2	1.5	-1.2	-0.4	-0.6	-0.9	-0.6	0.2
Pain all over the body in last month	0.3	0.3	2.1	-0.0	0.1	1.4	-0.1	-0.4	-0.2	-0.4	-0.0	-0.1	1.0	0.6
Neuroticism score	0.3	0.6	1.0	-0.9	-0.1	-0.7	-0.9	0.7	-1.0	-1.0	-1.0	-0.3	-0.6	-0.8
Pulse rate	0.3	0.6	1.8	0.6	0.2	0.3	0.7	-0.6	0.2	1.1	1.2	1.4	-0.3	0.4
Peak expiratory flow (PEF)	0.3	0.6	3.0	0.1	-0.9	1.7	0.2	0.7	1.6	0.3	0.0	0.2	-0.1	-0.4
Medication: Paracetamol	0.3	0.5	3.0	-0.5	-0.7	-0.3	-0.6	-0.7	-1.7	-0.4	-0.6	-0.3	-0.7	-0.1
Glaucoma (self-reported)	0.3	0.4	2.7	-0.0	0.1	-0.9	0.0	1.6	0.0	-0.1	-0.2	-0.6	-0.2	0.1
Arm fat-free mass (right)	0.3	1.7	10.5	1.1	0.1	0.9	1.1	-3.2	0.4	1.0	1.0	-0.0	1.1	1.2
Number of full brothers	0.3	0.3	1.9	0.2	0.2	0.0	0.1	-0.9	0.6	-0.2	-0.2	-0.6	1.4	0.1
Arm predicted mass (right)	0.3	1.6	8.4	1.2	0.2	0.9	1.2	-2.9	0.3	1.1	1.0	-0.0	1.1	1.3
Chest pain or discomfort	0.3	0.4	1.5	0.1	0.9	1.2	0.1	0.9	0.8	0.0	0.1	-0.7	-0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.3	0.5	1.5	0.8	0.5	-1.1	0.7	0.8	0.6	-0.4	-0.4	0.5
Long-standing illness, disability or infirmity	0.3	0.5	1.7	0.6	-0.1	0.7	0.7	1.0	0.4	0.6	0.5	0.6	0.8	1.3
Medication for cholesterol	0.3	0.4	2.5	0.4	-0.1	-0.8	0.3	0.2	-1.0	0.3	-0.1	1.6	-0.1	0.3
Leg predicted mass (right)	0.3	1.4	8.1	1.0	1.0	0.2	1.1	-2.8	0.3	1.1	1.0	0.5	-0.0	1.1
Number of self-reported non-cancer illnesses	0.3	0.6	2.6	0.3	1.1	-0.0	0.5	0.4	1.6	0.5	0.8	-0.9	-0.0	0.7
Average weekly champagne plus white wine intake	0.3	0.4	2.0	-0.2	-1.4	-1.3	-0.1	-0.2	-0.3	0.2	0.5	0.5	-0.3	-0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.8	-0.1	-0.1	0.6	0.0	0.3	1.7	-0.1	-0.4	-0.4	-0.1	0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.1	0.2	-1.4	0.7	0.1	-0.0	-0.4	-0.1	-0.2	1.2	0.1	0.3
Medication: Paracetamol	0.3	0.5	2.4	-0.7	-0.6	-0.5	-0.8	-0.5	-1.5	-0.3	-0.5	-0.4	-0.6	-0.3
Leg fat percentage (left)	0.3	0.9	3.2	0.6	-1.8	0.0	0.6	-1.7	-1.1	0.3	0.1	-0.8	0.5	1.1
Irritability	0.3	0.5	1.9	-0.5	1.4	0.0	-0.5	-0.2	1.1	-0.4	0.1	-0.5	-0.9	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.6	0.3	1.2	0.4	0.2	-0.5	0.6	-0.2	-0.3	-1.3	0.4	0.5
Supplements: Calcium	0.3	0.4	1.5	-0.1	-0.1	1.1	0.1	0.6	1.2	-0.1	0.2	0.6	0.3	-0.5
Leg fat mass (left)	0.3	1.0	6.4	0.5	-1.3	0.2	0.5	-2.5	-0.7	0.4	0.2	-0.8	0.3	1.0
Arm predicted mass (left)	0.3	1.3	11.1	0.7	-0.2	0.3	0.7	-3.3	-0.4	0.7	0.6	-0.4	0.6	0.9
Bipolar Disorder (2018)	0.2	0.2	0.8	0.3	0.6	-0.9	0.3	0.8	-0.2	0.1	-0.2	-0.4	0.6	0.3
Bipolar Disorder or Schizophrenia	0.2	0.6	1.5	-0.4	0.5	0.5	-0.3	1.0	1.0	-0.6	-0.8	-0.9	1.2	-0.1
Depressed Affect (Nagel 2018)	0.2	0.3	1.7	0.1	-0.3	0.8	0.1	-0.5	-0.6	-0.1	-0.5	1.3	0.4	0.3
Neuroticism (Nagel 2018)	0.2	0.5	1.0	-0.8	0.5	0.3	-0.9	0.4	-0.9	-0.9	-1.0	-0.2	-0.7	-0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.6	0.3	-0.8	-1.3	0.3	-0.8	-0.8	0.5	0.3	-0.2	0.7	-0.5
Breast Cancer	0.2	0.5	2.0	0.3	-0.8	1.1	0.2	1.4	0.4	0.6	0.6	0.3	0.9	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	0.1	-0.5	-0.5	0.0	0.3	-1.0	0.2	-0.1	0.6	-1.0	0.0
BMI	0.2	1.1	6.9	0.2	-0.5	-1.0	0.2	-2.6	-0.8	0.5	0.3	-1.0	-1.4	0.5
Height	0.2	4.6	15.7	-2.4	0.1	0.4	-2.2	-4.0	0.9	-2.4	-2.6	-1.9	-1.8	-2.1
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.0	-0.3	-0.3	0.1	-0.4	-0.3	-0.6	-0.7	-0.5	-1.0	-0.4	-0.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	0.4	-0.0	-0.0	0.4	0.8	-0.2	0.3	0.2	0.3	0.9	0.4
Leg fat-free mass (left)	0.2	1.1	8.6	0.7	0.8	0.3	0.7	-2.9	0.1	0.7	0.7	0.1	-0.2	0.8
Body mass index (BMI)	0.2	0.9	4.5	0.3	-1.3	-0.3	0.3	-2.1	-1.3	0.3	0.1	-0.7	-0.1	0.8
Leg predicted mass (left)	0.2	1.1	8.9	0.7	0.8	0.4	0.7	-3.0	0.2	0.7	0.7	0.2	-0.2	0.7
Trunk fat mass	0.2	0.8	7.2	0.3	-0.7	0.2	0.4	-2.7	-0.3	0.0	-0.1	-0.5	-0.1	0.9
Forced vital capacity (FVC)	0.2	0.8	3.6	0.4	0.1	1.7	0.5	-1.9	1.3	0.5	0.1	0.3	0.1	0.2
Fluid intelligence score	0.2	0.4	2.3	0.4	-0.1	-0.2	0.5	-1.5	-0.8	0.9	0.4	0.1	0.6	0.0
Weight	0.2	1.2	10.3	0.5	-0.5	0.5	0.5	-3.2	-0.6	0.3	0.2	-0.6	0.2	0.9
Impedance of arm (right)	0.2	1.0	2.0	-1.2	1.0	-0.1	-1.1	1.4	0.3	-1.3	-1.2	-0.1	-1.3	-0.9
Trunk fat-free mass	0.2	1.0	9.5	0.4	0.0	0.8	0.4	-3.1	0.0	0.4	0.2	-0.5	0.5	0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	3.2	0.6	0.1	1.8	0.7	-1.2	1.2	0.9	0.7	0.4	0.1	0.3
Noisy workplace	0.2	0.3	0.6	0.5	0.7	-0.2	0.6	-0.4	0.7	0.7	0.5	0.6	0.0	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	2.1	-0.3	-0.0	-0.2	-0.3	1.2	0.2	-0.1	0.2	-1.4	-0.2	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.5	0.2	0.2	0.0	0.1	0.8	-1.2	0.3	0.3	0.3	0.4	0.2
Asthma	0.2	0.5	2.3	0.3	-0.3	0.5	0.2	1.5	-0.2	0.5	0.9	1.0	0.0	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.7	-0.1	-0.6	0.4	0.0	-0.6	0.1	0.3	0.7	1.3	0.2	0.2
Depression (self-reported)	0.2	0.3	0.7	-0.5	0.1	-0.2	-0.5	-0.6	-0.6	-0.8	-0.8	-0.2	-0.4	-0.4
Medication: Lansoprazole	0.2	0.3	1.8	-0.1	0.6	-0.3	-0.0	0.0	1.3	-0.3	-0.1	-0.1	-0.9	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.4	0.3	-0.3	1.8	0.4	-0.9	1.3	0.7	0.3	0.9	-0.6	0.0
Arm fat mass (right)	0.2	0.8	6.0	0.4	-0.9	0.1	0.3	-2.5	-0.9	0.0	-0.0	-0.7	0.1	0.9
Trunk predicted mass	0.2	1.0	9.2	0.4	0.1	0.8	0.4	-3.0	-0.0	0.4	0.3	-0.5	0.5	0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	2.5	0.6	-0.2	1.6	0.7	-1.2	1.3	0.8	0.3	1.2	-0.3	0.5
Body fat percentage	0.2	0.7	4.0	0.3	-1.1	-0.2	0.3	-2.0	-0.7	-0.1	-0.2	-0.6	-0.2	0.9
Leg fat percentage (right)	0.2	0.7	3.1	0.4	-1.5	0.3	0.4	-1.8	-0.7	0.2	0.1	-0.9	0.4	0.9
Comparative body size at age 10	0.2	0.5	1.8	0.4	-0.2	-0.7	0.4	-0.1	-1.2	0.7	0.3	1.3	-0.7	0.3
Wheeze or whistling in the chest in last year	0.2	0.3	1.6	0.5	-0.1	-0.4	0.3	1.3	-0.6	0.3	0.4	0.1	0.2	0.6
Neck or shoulder pain in last month	0.2	0.3	0.8	0.2	0.9	0.8	0.3	-0.2	0.4	0.9	0.7	0.6	0.3	0.4
Medication: Ibuprofen	0.2	0.2	1.0	-0.0	-0.5	-0.2	-0.0	-0.4	-0.6	0.2	0.4	1.0	0.4	0.2
Whole body fat mass	0.2	0.9	6.7	0.4	-1.0	0.2	0.4	-2.6	-0.4	0.1	0.1	-0.7	0.1	0.9
Leg fat mass (right)	0.2	0.9	6.3	0.5	-1.1	0.3	0.4	-2.5	-0.6	0.3	0.2	-0.8	0.2	0.9
Pulse rate, automated reading	0.2	0.6	1.5	0.7	0.2	-0.0	0.9	-0.8	0.2	0.9	1.2	1.0	0.5	0.8
Alcohol intake frequency.	0.2	0.4	1.4	-0.3	0.2	0.7	-0.4	-1.2	-0.8	-0.8	-0.8	0.1	-0.7	0.0
Comparative height size at age 10	0.2	1.3	8.2	-0.8	-0.0	0.0	-0.9	-2.9	-1.2	-1.0	-1.3	-0.0	-0.3	-0.7
Suffer from ‘nerves’	0.2	0.3	1.4	0.1	-0.3	-0.4	-0.0	1.2	-1.2	-0.2	-0.1	0.4	0.7	0.2
Whole body fat-free mass	0.2	1.1	10.3	0.6	0.3	0.6	0.6	-3.2	0.2	0.5	0.5	-0.3	0.2	0.5
Leg fat-free mass (right)	0.2	1.3	8.0	1.0	1.0	0.1	1.0	-2.8	0.2	1.1	1.0	0.4	-0.1	1.1
Mineral and other dietary supplements	0.2	0.3	2.8	-0.1	-0.1	-1.7	-0.0	0.3	-0.5	0.2	0.2	-0.1	0.4	-0.2
Whole body water mass	0.2	1.2	10.0	0.7	0.4	0.7	0.8	-3.2	0.3	0.7	0.6	-0.1	0.4	0.7
Arm fat mass (left)	0.2	0.9	5.8	0.7	-0.6	0.4	0.6	-2.4	-0.7	0.3	0.2	-0.3	0.3	1.2
Guilty feelings	0.2	0.3	1.2	-0.5	-0.8	0.7	-0.6	1.1	-0.5	-0.2	0.0	0.2	-0.2	-0.3
Basal metabolic rate	0.2	1.2	10.5	0.7	0.2	0.6	0.7	-3.2	-0.1	0.6	0.5	-0.2	0.2	0.8
Arm fat-free mass (left)	0.2	1.1	9.6	0.5	-0.3	0.5	0.5	-3.1	-0.4	0.4	0.2	-0.5	0.3	0.7
Age started oral contraceptive pill	0.2	0.2	1.4	-0.4	-1.2	0.4	-0.3	-0.0	0.3	-0.1	-0.0	0.6	-0.3	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.7	0.3	-0.3	-0.4	0.2	-1.3	0.4	-0.2	-0.1	-0.7	0.6	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.7	-0.2	-0.2	0.9	-0.1	0.0	0.0	0.2	0.4	0.5	0.1	-0.2
Rheumatoid Arthritis	0.1	0.1	0.5	0.1	0.2	0.6	0.2	0.0	0.7	-0.3	0.0	-0.1	-0.3	0.1
Blood Eosinophil Count	0.1	0.4	1.8	0.2	-0.9	0.0	0.1	0.6	-0.9	-0.2	-0.6	0.4	1.4	0.5
Blood White Count	0.1	0.7	5.2	-0.4	-0.5	-2.3	-0.3	0.7	0.2	-0.5	-0.6	-0.3	-0.6	0.1
Systolic Blood Pressure	0.1	0.4	1.2	0.3	-1.1	0.5	0.3	-0.9	0.7	-0.3	-0.4	-0.7	1.0	0.3
Smoking Status	0.1	0.3	1.7	-0.5	0.3	-0.5	-0.4	0.5	0.4	-0.1	-0.2	1.3	-0.7	-0.4
Relative age of first facial hair	0.1	0.3	1.0	-0.1	-0.5	-1.0	-0.2	0.3	-0.3	-0.3	-0.7	0.7	-0.9	-0.0
Impedance of leg (right)	0.1	0.5	1.5	-0.2	-0.0	1.1	-0.2	1.2	0.8	-0.7	-0.7	-0.5	0.7	-0.1
Trunk fat percentage	0.1	0.6	4.3	0.1	-0.9	-0.1	0.2	-2.1	-0.5	-0.2	-0.3	-0.4	-0.5	0.8
Hand grip strength (right)	0.1	0.3	1.3	0.4	0.2	-1.0	0.3	-0.0	-0.5	0.2	-0.1	-1.2	-0.3	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.9	0.5	0.0	0.7	0.5	-0.6	0.8	0.0	0.5	-0.1	-0.9	0.0
Sitting height	0.1	1.1	4.7	0.3	-0.5	1.8	0.4	-2.2	1.6	0.2	0.4	0.5	0.6	0.1
Impedance of leg (left)	0.1	0.3	1.1	0.1	-0.2	0.7	0.1	1.0	0.5	-0.4	-0.5	-0.3	0.9	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.3	0.3	-0.5	1.1	0.3	-0.3	0.9	-0.2	0.1	0.2	-0.9	-0.1
Arm fat percentage (right)	0.1	0.5	2.8	0.1	-0.7	-0.1	0.1	-1.7	-0.9	-0.2	-0.3	-0.5	-0.4	0.6
Impedance of arm (left)	0.1	0.6	2.5	-0.3	1.6	0.6	-0.2	1.0	1.1	-0.4	-0.3	0.5	-0.4	-0.0
Standing height	0.1	1.3	6.5	0.3	1.6	1.6	0.4	-2.5	1.5	0.1	0.1	-0.0	0.4	0.3
Breastfed as a baby	0.1	0.2	0.6	0.5	-0.3	-0.2	0.5	-0.8	0.3	0.4	0.3	0.2	0.1	0.1
Exposure to tobacco smoke outside home	0.1	0.1	0.6	0.2	-0.0	0.0	0.3	0.5	-0.3	0.1	-0.0	0.8	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.3	0.4	0.4	-0.5	0.4	0.4	-0.1	0.4	0.4	-0.2	0.5	0.6
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.8	-0.1	-0.9	0.1	-0.0	0.1	0.2	0.1	0.3	0.8	-0.1	-0.5
Knee pain experienced in last month	0.1	0.2	0.8	-0.2	-0.5	0.1	-0.2	-0.4	-0.9	0.0	0.3	-0.1	-0.8	0.2
Smoking status: Previous	0.1	0.2	0.7	-0.2	0.5	0.9	-0.1	0.5	0.5	-0.2	-0.4	0.2	0.3	-0.2
Arm fat percentage (left)	0.1	0.5	3.1	0.4	-0.5	0.2	0.4	-1.8	-0.6	0.1	0.0	-0.3	-0.1	0.9
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	0.1	0.3	-0.5	0.1	-0.5	0.4	0.0	0.2	0.7	-0.1	-0.2
Mood swings	0.1	0.3	1.3	0.3	-0.1	-0.1	0.2	-0.2	-0.8	-0.1	-0.4	1.1	0.3	0.7
Eye problems/disorders: Cataract	0.1	0.1	0.3	-0.0	0.5	0.1	0.0	-0.2	0.5	-0.0	0.2	0.2	-0.5	-0.2
High cholesterol (Self-reported)	0.1	0.1	0.5	0.2	-0.3	0.0	0.2	-0.4	-0.0	0.2	0.0	0.3	-0.4	0.7
Medication: Lisinopril	0.1	0.1	0.5	-0.0	-0.5	-0.2	0.0	-0.4	0.3	0.3	0.2	-0.7	-0.6	-0.1
Medication: Atorvastatin	0.1	0.1	0.4	-0.2	-0.6	0.4	-0.2	0.2	-0.4	-0.0	-0.1	-0.1	-0.3	0.1
Average weekly beer plus cider intake	0.1	0.1	0.5	0.2	-0.2	-0.7	0.2	0.1	-0.5	0.3	0.0	0.6	-0.0	0.4
Impedance of whole body	0.1	0.3	1.3	-0.2	0.7	0.4	-0.1	1.2	0.7	-0.6	-0.6	0.3	0.1	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.6	3.0	-0.4	-0.5	-1.0	-0.3	-0.4	-0.4	0.5	0.5	1.0	-1.7	-0.6
Tanning	0.0	0.4	2.6	0.3	0.8	-0.3	0.4	0.0	1.6	0.5	0.4	-0.4	-0.4	-0.1
Age at first live birth	0.0	0.1	0.3	-0.1	0.3	-0.4	-0.2	0.1	0.2	-0.3	-0.2	0.1	0.5	-0.4

Hub : Genes

CHKB-AS1

Models

Trait associations