TWAS hub - CHPF

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Papillary Cell Carcinoma	0.065	0.038	7.6e-03	-0.004	0.034	0.016	NA	0.012	7.4e-01	4.7e-03	3.9e-02	NA	6.0e-02
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.077	0.036	3.9e-05	0.063	0.084	0.078	NA	0.064	4.8e-05	2.7e-06	6.0e-06	NA	3.7e-05
3	TCGA	Thyroid Carcinoma	0.080	0.034	7.4e-05	0.041	0.020	0.023	NA	0.021	6.4e-05	4.0e-03	2.3e-03	NA	3.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate	10.1	17.1	22.5	-3.1	-4.4	-4.7
Pulse rate, automated reading	7.9	25.4	40.4	-2.5	-6.4	-5.4
Medication: Atenolol	4.8	6.0	10.4	-3.2	-0.9	-2.6
Irritability	4.6	7.8	11.8	-3.3	-0.9	-3.4
Medication: Blood pressure	4.2	7.5	10.2	-2.6	-2.3	-3.2
Medication for cholesterol, blood pressure or diabetes	3.9	6.5	9.7	2.2	2.2	3.1
Mineral and other dietary supplements	3.5	4.6	7.3	-1.4	-2.7	-2.2
Illnesses of father: High blood pressure	3.4	4.2	5.4	-1.5	-2.2	-2.3
Neck or shoulder pain in last month	3.3	4.7	8.9	-3.0	0.2	-2.3
Medication: Allopurinol	3.0	4.0	7.7	-2.8	-0.8	-1.9
Depressed Affect (Nagel 2018)	2.9	6.1	11.9	-3.5	2.3	-1.1
Multivitamins +/- minerals	2.9	3.7	6.3	0.7	2.5	2.1
Medication: Seretide 50 evohaler	2.8	3.2	3.3	-1.8	-1.8	-1.8
Diastolic blood pressure, automated reading	2.8	8.6	11.9	-1.7	-3.5	-3.3
Knee pain experienced in last month	2.7	4.1	5.7	1.7	1.9	2.4
Average weekly red wine intake	2.7	4.0	8.7	2.9	0.2	1.8
Supplements: Calcium	2.7	2.9	5.8	2.4	0.3	1.7
Long-standing illness, disability or infirmity	2.6	4.0	8.4	-2.9	-0.1	-1.9
Alzheimer’s Disease (in father)	2.5	2.7	3.3	-1.3	-1.7	-1.8
Exposure to tobacco smoke outside home	2.5	3.3	6.4	-0.4	2.5	1.8
Age at last live birth	2.5	3.6	5.1	2.2	1.2	2.1
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.0	6.6	-2.6	-0.5	-1.5
Ever had bowel cancer screening	2.5	2.9	7.3	-0.5	2.7	1.1
Risk taking	2.5	3.6	4.9	1.9	1.6	2.2
Neuroticism (2016)	2.4	3.5	5.1	-2.1	-1.0	-2.3
Taking other prescription medications	2.4	3.8	7.2	-2.7	-0.1	-2.0
Loneliness, isolation	2.4	3.3	7.2	-2.7	1.0	-1.3
Townsend deprivation index at recruitment	2.3	3.2	8.0	-2.8	1.0	-0.8
Alcohol usually taken with meals	2.3	3.7	5.8	2.4	-2.3	0.1
Medication: Amlodipine	2.3	3.2	5.0	-2.1	-0.5	-2.2
Bipolar Disorder (2018)	2.2	3.5	5.3	-2.3	-0.7	-2.2
Age at First Birth	2.2	3.1	5.2	1.1	2.3	1.7
Triglycerides	2.2	3.6	6.0	-1.3	-2.5	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	3.0	4.5	-2.1	-0.9	-1.9
Medication: Simvastatin	2.2	3.3	4.5	-1.0	-2.1	-2.1
Number of full sisters	2.2	2.7	4.1	-1.8	-0.8	-2.0
Leg pain on walking	2.2	2.7	3.8	1.4	1.5	1.9
Fasting Glucose	2.1	2.6	3.3	1.3	1.8	1.6
Vitamin and mineral supplements	2.1	2.9	5.9	-0.7	-2.4	-1.5
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.2	6.1	-2.5	1.9	-0.2
Wheeze or whistling in the chest in last year	2.1	3.7	7.7	-2.8	1.8	-0.6
Number of children fathered	2.1	2.4	4.9	-2.2	0.0	-1.5
Average weekly beer plus cider intake	2.1	3.0	3.9	1.8	1.3	2.0
Supplements: Glucosamine	2.0	2.6	3.5	1.1	1.9	1.7
Medication for pain relief, constipation, heartburn	2.0	3.4	8.1	0.1	-2.9	-1.4
Pack years of smoking	2.0	2.9	4.1	-2.0	-0.8	-2.0
Alzheimer’s Disease (including proxy)	1.9	2.8	4.0	-1.4	-1.5	-2.0
Lung FVC	1.9	9.7	21.3	-2.8	4.6	0.1
Supplements: Zinc	1.9	2.0	2.9	1.7	0.7	1.6
High blood pressure (mother)	1.9	2.7	3.9	-0.7	-2.0	-1.9
Impedance of arm (right)	1.9	9.0	15.1	3.9	-3.5	0.2
Illnesses of mother	1.9	2.4	4.7	0.1	2.2	1.5
Impedance of arm (left)	1.9	8.7	17.8	4.2	-2.8	0.6
Emphysema/chronic bronchitis	1.9	2.2	4.4	-2.1	0.8	-1.2
Body Mass Index (BMI) (2010)	1.8	2.5	5.4	-2.3	1.2	-0.8
Had menopause	1.8	2.2	3.2	0.7	1.7	1.8
Falls in the last year	1.8	2.4	5.0	-2.2	1.5	-0.1
Hypertension (Self-reported)	1.8	5.1	9.6	-3.1	-0.5	-2.3
Financial difficulties in last 2 years	1.7	2.2	4.6	-0.6	2.2	1.3
Medication: Ramipril	1.7	2.2	5.2	-2.3	0.8	-0.8
Exposure to tobacco smoke at home	1.7	1.9	4.8	-0.6	2.2	0.6
Pulse wave reflection index	1.7	2.1	3.3	0.2	1.7	1.8
Medication: Ventolin 100micrograms inhaler	1.7	2.2	3.9	-0.4	-2.0	-1.6
Number of self-reported non-cancer illnesses	1.7	3.0	5.2	-2.3	-0.4	-1.9
Miserableness	1.7	3.0	6.9	-2.6	0.4	-1.4
Hearing aid user	1.7	2.0	3.1	-1.8	-0.8	-1.5
Coronary Artery Disease (CAD)	1.6	1.9	3.5	0.5	1.4	1.9
Fed-up feelings	1.6	3.0	6.1	-2.5	1.6	-0.6
Number of incorrect matches in round	1.6	2.7	5.9	1.4	-2.4	-0.5
Medication: Cholesterol lowering	1.6	2.5	4.0	-1.5	-1.1	-2.0
Wears glasses or contact lenses	1.6	1.8	2.8	-1.7	1.6	0.3
Financial situation satisfaction	1.6	1.9	4.6	-0.2	2.1	1.1
Tinnitus: Yes, now most or all of the time	1.6	1.9	3.8	1.9	-0.2	1.4
High cholesterol (Self-reported)	1.6	2.9	4.9	-0.7	-1.8	-2.2
HbA1C	1.5	1.7	2.0	-1.2	-1.4	-1.3
Cardiovascular Disease	1.5	4.9	7.0	-2.3	-1.5	-2.7
Diabetes (father)	1.5	1.8	3.3	-1.8	-1.1	-1.0
Nervous feelings	1.5	2.8	4.2	-0.7	-2.0	-1.9
Qualifications: A levels/AS levels or equivalent	1.5	3.2	6.8	1.6	-2.6	-0.6
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	2.1	1.5	1.3	1.4
Gout (self-reported)	1.5	2.1	4.8	-2.2	-0.1	-1.1
Unable to work because of sickness or disability	1.5	1.9	3.0	-1.6	1.7	0.2
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	3.1	-1.8	1.5	-0.4
Depression (Nagel 2018)	1.4	2.2	3.3	-1.6	-0.7	-1.8
Heel T-Score	1.4	11.4	22.7	-1.5	-4.8	-3.0
Alcohol intake versus 10 years previously	1.4	2.1	4.5	0.3	-2.1	-1.3
Worrier / anxious feelings	1.4	2.7	4.4	0.4	2.1	1.9
Medication: Paracetamol	1.4	2.3	4.9	0.3	2.2	1.4
Medication: Omeprazole	1.4	1.7	3.2	-1.8	1.1	-0.7
Overall health rating	1.4	2.9	5.8	-2.4	-0.0	-1.7
Qualifications: nursing, teaching	1.4	2.2	4.5	1.2	-2.1	-0.8
Commuting to job workplace: Public transport	1.4	1.6	2.9	-1.0	-1.0	-1.7
Vascular/heart problems diagnosed by doctor	1.4	3.8	7.2	2.7	0.6	2.0
HDL Cholesterol	1.3	2.1	4.2	0.7	2.0	1.3
Average weekly spirits intake	1.3	1.6	3.7	-1.9	-0.0	-1.1
Frequency of depressed mood in last 2 weeks	1.3	1.8	2.4	-1.6	-0.9	-1.5
Diabetes (self-reported)	1.3	2.0	3.7	-1.9	-0.7	-1.4
Number of live births	1.3	1.9	3.2	0.4	1.8	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.7	-0.3	1.9	0.9
Length of working week for main job	1.3	1.5	2.5	-1.6	-0.4	-1.3
Blood clot in the leg (DVT)	1.3	1.7	2.2	-1.3	-1.0	-1.5
Smoking status: Previous	1.3	2.0	4.6	1.0	-2.1	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	3.3	-1.1	1.8	0.4
Mother’s age at death	1.3	1.7	3.6	1.9	-0.1	1.2
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.1	-1.3	1.8	0.4
Impedance of whole body	1.3	6.6	11.7	3.4	-2.8	0.5
Bipolar Disorder or Schizophrenia	1.2	2.9	4.5	-1.9	-0.9	-2.1
Prostate Cancer	1.2	1.7	2.9	-1.2	-0.8	-1.7
Systolic blood pressure, automated reading	1.2	3.6	4.3	-2.0	-1.5	-2.1
Pack years adult smoking proportion	1.2	1.8	3.6	-1.9	-0.0	-1.4
High blood pressure	1.2	3.2	5.7	-2.4	-0.7	-1.9
Qualifications: None of the above	1.2	2.5	4.8	-2.2	1.2	-1.1
Number of full brothers	1.2	1.6	2.5	-1.4	1.6	-0.3
Angina (self-reported)	1.2	1.6	3.5	-1.9	0.5	-1.0
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.5	1.9	-0.9	0.4
Mood swings	1.2	2.2	4.9	-2.2	0.8	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	4.5	-0.9	2.1	0.7
Medication for cholesterol	1.2	1.9	4.7	2.2	-0.5	0.8
Medication: Gliclazide	1.2	1.4	1.7	0.9	1.2	1.3
Average weekly champagne plus white wine intake	1.2	1.7	3.7	1.9	0.5	1.1
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.4	-1.8	0.4	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	1.8	-1.3	-1.1	-1.4
Neuroticism (Nagel 2018)	1.1	2.6	4.5	-2.1	1.6	-0.9
Type 2 Diabetes (T2D) (2012)	1.1	1.2	1.9	1.3	0.1	1.4
Angina	1.1	1.5	3.3	-1.8	0.6	-0.9
Diabetes (mother)	1.1	1.4	3.2	-0.5	-1.8	-0.9
Heart attack	1.1	1.3	2.9	-1.7	0.5	-0.9
Headache pain in last month	1.1	1.8	3.1	-1.8	-0.6	-1.4
Alcohol intake frequency.	1.1	2.6	3.5	-1.9	-0.9	-1.9
Comparative height size at age 10	1.1	6.0	10.4	3.2	1.2	2.5
Number of operations (self-reported)	1.1	1.7	2.1	-1.4	1.4	1.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.2	2.3	-0.3	1.5	1.1
Stomach or abdominal pain in last month	1.0	1.3	1.9	-1.4	0.5	-1.3
High blood pressure (siblings)	1.0	1.5	2.5	-1.6	0.5	-1.3
Supplements: Vitamin C	1.0	1.2	3.2	0.2	1.8	0.7
Diabetes diagnosed by doctor	1.0	1.7	2.6	-1.6	-0.9	-1.3
Medication: Blood pressure	1.0	1.9	4.1	-2.0	1.2	-0.3
Lung FEV1/FVC ratio	0.9	4.7	10.8	1.3	-3.3	-1.3
Neuroticism	0.9	2.3	4.1	-2.0	1.3	-1.0
Medication: Co-codamol	0.9	1.0	2.1	-1.0	1.4	0.1
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.2	-0.1	1.5	0.8
Serious illness, injury or assault to yourself	0.9	1.2	1.9	-1.4	-0.6	-1.1
Breastfed as a baby	0.9	1.1	1.5	-1.2	-0.8	-1.2
Medication: Lisinopril	0.9	1.2	2.9	1.7	-0.4	0.6
Alcohol drinker status: Previous	0.9	1.0	2.0	-0.8	-0.6	-1.4
Intelligence (Savage-Jansen 2018)	0.8	2.6	5.2	1.4	-2.3	-0.8
Breast Cancer	0.8	2.0	3.4	1.8	0.5	1.5
Mean Putamen Volume	0.8	0.9	1.3	-1.1	1.2	0.4
Allergy or Eczema	0.8	2.0	3.1	0.7	1.8	1.6
Type 2 Diabetes (T2D) (2018)	0.8	1.6	2.9	-1.7	-0.6	-1.2
Number of treatments/medications taken	0.8	1.5	2.8	-1.7	1.1	-0.6
Current tobacco smoking	0.8	1.3	2.5	-0.2	1.6	1.2
Average weekly fortified wine intake	0.8	0.9	2.0	-0.2	-0.8	-1.4
Age when periods started (menarche)	0.8	1.8	3.0	1.5	-1.7	-0.4
Fluid intelligence score	0.8	1.6	4.0	2.0	-0.7	0.6
Neuroticism score	0.8	1.6	3.3	-1.8	0.8	-1.0
Asthma	0.8	1.6	3.1	-1.8	0.3	-1.2
Standing height	0.8	8.0	19.4	4.4	-1.5	1.5
Health satisfaction	0.8	1.0	2.1	-1.4	0.1	-0.9
Qualifications: College or University degree	0.8	2.4	4.7	1.4	-2.2	-0.6
Migraine (self-reported)	0.8	0.9	2.7	-1.6	-0.1	-0.4
Medication: Aspirin	0.8	1.1	2.4	-0.3	1.6	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.4	-1.2	0.8	-0.9
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.4	1.0	0.8	1.2
Medication: Aspirin	0.8	1.0	2.1	-0.1	1.4	1.0
Alcohol drinker status: Never	0.8	1.0	1.6	-1.3	-0.8	-0.8
Fractured/broken bones in last 5 years	0.8	1.0	1.6	-0.7	-1.0	-1.3
Schizophrenia (2014)	0.7	1.6	2.3	-0.6	-1.4	-1.5
Medication for hormone replacement therapy	0.7	0.8	1.3	-0.9	-0.5	-1.1
Illnesses of siblings	0.7	0.9	1.8	1.0	-1.4	0.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.8	0.1	-1.3	-0.8
Chest pain or discomfort	0.7	1.0	2.0	-0.1	1.4	0.9
Back pain experienced in last month	0.7	1.0	2.3	-0.5	1.5	0.5
Medication: Paracetamol	0.7	1.1	2.3	-0.1	1.5	0.9
Myopia	0.7	1.0	2.3	1.5	0.1	0.9
Heart disease (siblings)	0.7	0.9	2.3	-1.5	0.2	-0.6
Alzheimer’s Disease (in mother)	0.6	0.7	1.0	-0.6	-0.9	-1.0
Verbal and Numeric Reasoning (VNR)	0.6	1.5	2.3	1.5	-1.5	-0.0
Chronotype (morning person)	0.6	1.5	3.1	-0.1	1.8	1.1
Hearing difficulty/problems: Yes	0.6	0.8	1.9	-0.8	1.4	-0.1
Past tobacco smoking	0.6	1.0	2.5	-0.5	1.6	0.6
Forced vital capacity (FVC)	0.6	2.4	6.5	0.1	2.5	0.8
Pain all over the body in last month	0.6	0.6	1.2	-1.1	0.8	0.3
Medication: Lansoprazole	0.6	0.7	1.2	-1.1	0.9	-0.3
Lung cancer (father)	0.6	0.7	1.2	-1.1	0.9	-0.4
Tense / ‘highly strung’	0.6	1.0	1.6	-1.3	0.5	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.6	-1.2	0.2	-1.0
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.6	1.1	-1.2	0.6
Forced vital capacity (FVC), Best measure	0.6	2.3	4.6	0.7	2.1	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.4	1.6	-1.2	-0.2
Asthma (self-reported)	0.6	1.2	2.3	-1.5	0.0	-1.2
Smoking status: Current	0.6	0.9	1.6	-0.2	1.3	1.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.9	0.2	1.4	0.6
Medication: Bendroflumethiazide	0.6	0.9	2.5	-1.6	0.4	-0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.5	-0.5	-0.7	-1.2
Worry (Nagel 2018)	0.5	1.0	2.2	-0.0	1.5	0.8
Systolic Blood Pressure	0.5	2.5	3.3	-1.0	-1.8	-1.8
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.1	-1.1	0.9	0.1
Maternal smoking around birth	0.5	0.7	1.8	-0.0	-1.3	-0.7
Qualifications: CSEs or equivalent	0.5	0.6	1.0	-1.0	-0.4	-0.8
Impedance of leg (left)	0.5	2.6	4.0	2.0	-1.8	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.6	1.3	0.1	1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.2	0.4	1.1	0.7
Father’s age at death	0.5	0.6	1.2	1.1	-0.6	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	1.9	1.4	1.2	1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	-1.3	-0.2	-0.4
Loud music exposure frequency	0.5	0.6	1.0	0.8	-1.0	0.3
Leg fat percentage (right)	0.5	1.9	5.1	-2.3	0.6	-0.5
Age at first live birth	0.5	1.0	1.9	1.4	0.3	1.0
Pulse wave peak to peak time	0.5	0.6	1.1	1.1	0.7	0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.0	-0.8	1.0	0.2
Suffer from ‘nerves’	0.5	0.8	1.8	-0.1	1.3	0.8
Age started oral contraceptive pill	0.5	0.6	1.4	-0.3	-1.2	-0.5
Ever depressed for a whole week	0.5	0.6	1.2	1.1	0.3	0.8
Commuting to job workplace: Cycle	0.5	0.6	1.2	1.1	-0.1	0.7
Basal cell carcinoma (self-reported)	0.5	0.5	1.2	0.6	-1.1	-0.2
Primary Biliary Cirrhosis	0.4	0.6	1.1	-1.0	-0.5	-0.7
Rheumatoid Arthritis	0.4	0.6	0.9	-0.8	0.9	-0.4
Blood Red Count	0.4	3.9	6.1	-1.4	-2.5	-2.0
Height	0.4	7.1	15.0	3.9	-2.4	0.7
Impedance of leg (right)	0.4	2.1	3.6	1.6	-1.9	0.4
Relative age voice broke	0.4	0.6	1.3	0.2	-1.1	-0.6
Body mass index (BMI)	0.4	1.8	3.9	-2.0	1.2	-0.3
Happiness	0.4	0.5	0.8	0.2	-0.8	-0.9
Depression (self-reported)	0.4	0.5	0.9	-0.1	-0.9	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.5	-0.4	1.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.3	1.1	0.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.2	-0.3	1.1	-0.3
Friendships satisfaction	0.4	0.5	1.1	1.0	0.2	0.7
Breast cancer (self-reported)	0.4	0.4	0.9	1.0	-0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.4	-0.5	1.5	-0.0
Medication: Atorvastatin	0.4	0.6	1.2	-0.5	-0.4	-1.1
Leg fat percentage (left)	0.4	1.6	4.0	-2.0	0.9	-0.2
Cholesterol lowering medication	0.4	0.6	0.9	-1.0	-0.4	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	0.9	-0.4	0.5
Lupus	0.3	0.4	0.7	-0.6	0.8	0.4
Ulcerative Colitis	0.3	0.5	0.8	-0.7	0.9	0.4
Respiratory disease	0.3	0.7	1.5	-0.7	1.2	0.3
Hand grip strength (left)	0.3	0.8	1.9	1.4	0.3	0.7
Sensitivity / hurt feelings	0.3	0.6	0.9	-0.2	-0.9	-0.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	-0.8	-0.5	-0.5
Severe depression (siblings)	0.3	0.4	0.6	-0.5	0.6	0.7
Hand grip strength (right)	0.3	0.8	2.0	1.4	-0.6	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.6	-0.8	0.6	-0.2
Medication: Levothyroxine sodium	0.3	0.5	1.2	-0.3	1.1	0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.7	-0.1	0.8	0.7
Mouth/teeth dental problems	0.3	0.5	0.7	-0.7	-0.6	-0.8
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.0	0.7	1.4	0.7
Noisy workplace	0.3	0.4	0.6	-0.4	0.8	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	0.6	-0.7	-0.7	-0.2
Comparative body size at age 10	0.3	0.9	2.3	-0.5	1.5	0.4
Shortness of breath walking on level ground	0.3	0.4	0.8	-0.9	-0.1	-0.6
Eye problems/disorders: None of the above	0.3	0.3	0.9	0.9	0.2	0.3
Heart disease (mother)	0.3	0.3	0.5	-0.0	-0.6	-0.7
Family relationship satisfaction	0.3	0.4	0.8	0.4	0.9	0.4
Commuting to job workplace: Walk	0.3	0.3	0.9	-1.0	0.1	0.1
Illnesses of father: None of the above (group 1)	0.3	0.3	0.5	0.5	0.7	0.5
Schizophrenia (2018)	0.2	0.5	1.0	-0.5	-0.5	-1.0
Ulcerative Colitis (UC)	0.2	0.3	0.6	-0.8	0.6	0.0
Reaction Time	0.2	0.5	1.1	-0.5	-0.2	-1.1
Ovarian Cancer	0.2	0.3	0.8	0.3	0.9	0.3
LDL Cholesterol	0.2	0.2	0.6	-0.3	0.8	0.2
BMI	0.2	1.3	3.1	-1.8	0.8	-0.4
Waist Hip Ratio (WHR)	0.2	0.9	2.5	0.5	-1.6	-0.3
Medication: Metformin	0.2	0.2	0.5	-0.7	0.4	0.2
Allergy	0.2	0.4	0.8	0.9	-0.6	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.8	0.9	0.3	0.3
Mouth/teeth dental problems: Dentures	0.2	0.3	0.5	-0.5	-0.4	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.4	0.6	0.2	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.5	0.2	0.7	0.6
Worry too long after embarrassment	0.2	0.3	0.5	0.3	-0.5	-0.7
Medication: Ibuprofen	0.2	0.3	0.4	0.6	0.5	0.3
Mean time to correctly identify matches	0.2	0.5	1.0	-0.6	-0.1	-1.0
Arm predicted mass (right)	0.2	1.2	2.7	-0.0	1.6	1.0
Had major operations	0.2	0.2	0.7	-0.8	-0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	0.6	-0.6	-0.0
Illnesses of siblings: Diabetes	0.2	0.2	0.6	-0.8	0.3	-0.1
Eye problems/disorders: Cataract	0.2	0.2	0.4	-0.4	0.6	0.2
Ever taken oral contraceptive pill	0.2	0.2	0.4	-0.2	-0.7	-0.3
Crohns Disease (2017)	0.1	0.1	0.3	0.1	0.5	0.3
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	-0.6	0.6	0.0
Major Depression (MDD)	0.1	0.2	0.3	-0.5	0.4	0.0
Blood White Count	0.1	0.7	1.7	-0.1	-1.3	-0.6
Smoking Status	0.1	0.3	0.6	0.6	-0.8	0.1
Tanning	0.1	0.9	1.1	0.9	0.9	1.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	-0.2	0.3	0.5
Leg fat-free mass (left)	0.1	0.4	0.7	0.6	0.8	0.5
Trunk fat percentage	0.1	0.4	0.7	0.7	-0.8	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.5	0.5	-0.7	0.3
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.4	-0.1	0.6	0.2
Sitting height	0.1	0.7	1.8	1.3	-0.6	0.3
Leg predicted mass (left)	0.1	0.4	0.7	0.5	0.8	0.5
Waist circumference	0.1	0.3	0.7	-0.8	-0.3	-0.2
Had other major operations	0.1	0.1	0.3	-0.0	0.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	0.0	0.4	0.2
Arm fat percentage (right)	0.1	0.2	0.4	-0.4	-0.6	-0.4
Time employed in main current job	0.1	0.1	0.3	0.2	-0.2	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.3	-0.6	0.5	-0.2
Prospective memory result	0.1	0.1	0.2	-0.4	-0.2	-0.0
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	0.1	0.7	0.6
Birth weight of first child	0.1	0.2	0.5	0.3	-0.1	-0.7
Peak expiratory flow (PEF)	0.1	0.3	0.5	-0.6	-0.1	-0.7
Glaucoma (self-reported)	0.1	0.1	0.1	-0.3	-0.1	-0.3
Birth weight	0.1	0.3	0.7	-0.4	0.0	-0.9
Arm fat-free mass (right)	0.1	0.4	1.0	-0.2	1.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.4	-0.1	0.2
Leg fat mass (right)	0.1	0.5	1.1	-1.1	0.7	0.2
Illnesses of father: Heart disease	0.1	0.1	0.4	0.1	0.6	0.1
Whole body fat-free mass	0.1	0.3	0.8	0.2	0.9	0.4
Leg fat-free mass (right)	0.1	0.6	0.7	0.8	0.8	0.6
Osteoporosis (self-reported)	0.1	0.1	0.1	0.4	-0.3	0.0
Osteoarthritis (self-reported)	0.1	0.1	0.1	-0.1	0.4	-0.2
Leg predicted mass (right)	0.1	0.6	0.7	0.8	0.9	0.6
Guilty feelings	0.1	0.2	0.5	-0.1	0.0	-0.7
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.1	-0.4	-0.2
Ever smoked	0.1	0.2	0.5	0.7	-0.0	0.3
Basal metabolic rate	0.1	0.3	0.7	0.2	0.9	0.5
Arm fat-free mass (left)	0.1	0.5	1.0	-0.2	1.0	0.6
Pain experienced in last month	0.1	0.1	0.1	0.3	-0.3	0.3
Leg fat mass (left)	0.1	0.6	1.0	-1.0	0.8	0.3
Arm predicted mass (left)	0.1	0.5	1.0	-0.3	1.0	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.1	-0.4	0.3	0.0
Blood Eosinophil Count	0.0	0.2	0.4	-0.7	0.4	-0.2
Blood Platelet Count	0.0	0.1	0.3	-0.5	-0.3	0.1
Hypothyroidism (self reported)	0.0	0.0	0.0	-0.0	0.1	0.1
Hair Pigment	0.0	0.3	0.4	-0.6	0.3	-0.5
Relative age of first facial hair	0.0	0.1	0.2	0.4	0.0	0.3
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	-0.0	-0.1	-0.2
Trunk fat mass	0.0	0.2	0.3	0.4	-0.5	-0.0
Hearing difficulty/problems with background noise	0.0	0.0	0.1	-0.0	0.3	0.1
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	-0.0	0.2	0.1
Weight	0.0	0.1	0.2	0.1	0.5	0.4
Trunk fat-free mass	0.0	0.2	0.7	-0.2	0.8	0.2
Hip circumference	0.0	0.1	0.1	0.3	0.2	0.4
Arm fat mass (right)	0.0	0.1	0.2	-0.4	-0.1	-0.0
Trunk predicted mass	0.0	0.2	0.6	-0.2	0.8	0.2
Body fat percentage	0.0	0.0	0.1	-0.2	-0.3	-0.1
Whole body fat mass	0.0	0.0	0.1	-0.2	0.0	0.1
Arm fat percentage (left)	0.0	0.1	0.1	-0.3	-0.1	-0.2
Whole body water mass	0.0	0.3	0.6	0.1	0.8	0.3
Arm fat mass (left)	0.0	0.1	0.1	-0.4	0.3	0.2

Hub : Genes

CHPF

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Trait associations