TWAS hub - CHPF2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Coronary	0.4250	0.1030	1.5e-03	0.020	NA	0.019	NA	0.042	6.7e-02	NA	7.7e-02	NA	1.5e-02
2	GTEx	Cells EBV-transformed lymphocytes	0.3290	0.1180	7.3e-03	0.012	NA	-0.008	NA	-0.002	1.3e-01	NA	8.1e-01	NA	4.0e-01
3	GTEx	Cells Transformed fibroblasts	0.1170	0.0430	5.7e-03	0.029	NA	0.003	NA	0.000	3.0e-03	NA	1.8e-01	NA	3.0e-01
4	GTEx	Lung	0.1083	0.0377	2.4e-03	-0.001	NA	0.001	NA	0.002	4.0e-01	NA	2.7e-01	NA	2.0e-01
5	GTEx	Pancreas	0.2850	0.1000	7.4e-03	-0.003	NA	0.001	NA	-0.006	4.6e-01	NA	2.9e-01	NA	7.0e-01
6	GTEx	Spleen	0.4580	0.1090	7.7e-04	0.162	NA	0.134	NA	0.248	6.1e-05	NA	2.6e-04	NA	4.8e-07
7	YFS	Blood	0.0344	0.0123	1.2e-03	0.009	0.006	0.014	0.011	0.012	4.3e-04	4.4e-03	1.1e-05	1e-04	4.3e-05
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0335	0.0178	2.4e-03	0.041	0.015	0.005	NA	0.020	2.1e-05	6.5e-03	8.5e-02	NA	2.5e-03
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0708	0.0295	1.1e-05	0.034	0.055	0.040	NA	0.043	1.0e-04	8.6e-07	2.4e-05	NA	1.1e-05
10	TCGA	Brain Lower Grade Glioma	0.0316	0.0168	2.5e-03	0.020	0.024	0.015	NA	0.019	2.3e-03	8.1e-04	7.3e-03	NA	2.6e-03
11	TCGA	Prostate Adenocarcinoma	0.0614	0.0342	2.6e-04	0.022	0.017	0.021	NA	0.024	2.2e-03	5.8e-03	2.4e-03	NA	1.3e-03
12	TCGA	Thyroid Carcinoma	0.0340	0.0170	3.1e-03	0.032	0.026	0.026	NA	0.025	4.2e-04	1.2e-03	1.4e-03	NA	1.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Basal cell carcinoma (self-reported)	9.8	11.6	19.3	3.1	2.5	3.5	4.0	0.0	3.4	3.5	3.6	2.7	4.4	3.9	4.1
Smoking status: Previous	7.2	10.8	16.4	3.0	-0.4	4.0	3.5	2.9	3.2	2.4	3.8	3.4	3.3	4.0	3.8
Number of live births	5.7	8.0	12.0	3.2	0.5	3.1	3.3	1.7	3.0	1.9	3.3	3.2	2.4	3.5	3.3
Ever had stillbirth, spontaneous miscarriage or termination	5.6	6.0	10.2	2.4	0.3	2.9	3.2	0.6	2.4	2.4	3.0	2.0	2.7	2.5	3.1
Ever smoked	5.6	9.9	16.2	2.0	-1.4	3.4	3.4	3.2	3.3	2.4	3.4	4.0	2.8	4.0	3.4
Past tobacco smoking	5.5	10.1	16.2	-2.4	1.1	-3.6	-3.3	-3.0	-3.1	-2.3	-3.7	-3.8	-2.9	-4.0	-3.7
Pulse wave Arterial Stiffness index	5.4	6.4	12.2	2.4	0.6	1.2	2.9	1.2	3.5	1.7	3.1	2.8	2.5	3.0	3.3
Ever taken oral contraceptive pill	4.7	5.3	9.7	1.6	-1.0	3.0	2.3	0.9	2.2	1.8	2.4	2.0	2.8	3.0	3.1
Eye problems/disorders: None of the above	4.1	4.8	9.2	-1.5	-0.2	-2.8	-2.4	-1.5	-2.2	-1.3	-2.5	-3.0	-1.9	-2.7	-2.5
Fractured/broken bones in last 5 years	3.9	5.0	7.5	-2.5	-1.3	-2.1	-2.6	-0.1	-2.7	-2.7	-2.6	-2.3	-2.2	-2.2	-2.0
Guilty feelings	3.7	5.6	12.1	1.7	0.7	2.5	2.8	0.6	1.7	2.1	3.3	1.2	2.9	2.9	3.5
Eye problems/disorders: Glaucoma	3.6	4.2	7.9	1.0	2.8	1.9	2.2	-0.3	2.2	2.2	2.3	2.1	1.7	2.2	2.3
Age when periods started (menarche)	3.5	8.3	14.8	2.7	2.0	3.5	3.4	2.0	2.9	2.5	3.0	3.9	2.3	2.9	2.9
Pulse wave peak to peak time	3.5	4.1	8.2	-2.0	-0.5	-0.6	-2.3	-0.8	-2.9	-1.3	-2.6	-2.2	-2.0	-2.4	-2.7
Age at last live birth	2.9	4.2	9.0	2.2	1.6	3.0	2.7	-0.8	2.1	1.1	2.1	0.9	2.6	2.2	1.9
Mother’s age at death	2.9	3.7	6.0	1.2	-0.3	1.8	2.3	0.9	2.1	2.2	2.0	2.1	2.0	2.3	2.5
Sensitivity / hurt feelings	2.7	4.7	8.2	2.1	-1.7	2.6	1.9	2.0	1.8	0.2	2.7	1.9	2.4	2.6	2.9
Mood swings	2.7	4.8	10.1	-1.8	-0.6	-2.5	-2.7	-1.1	-3.2	-2.8	-2.0	-2.4	-1.7	-2.2	-1.9
Height	2.6	50.3	75.3	5.2	2.7	8.1	7.8	4.0	7.3	7.9	7.4	8.4	6.3	8.7	8.3
Glaucoma (self-reported)	2.6	3.1	4.5	1.2	1.6	1.6	2.1	0.1	2.1	1.4	2.1	2.1	1.6	2.1	1.9
Forced expiratory volume in 1-second (FEV1), predicted	2.6	5.3	7.5	1.7	2.1	2.6	2.6	1.5	2.3	2.7	2.5	2.6	2.0	2.5	2.3
Pack years of smoking	2.6	3.8	6.7	-2.1	-2.5	-2.2	-2.1	-0.9	-1.5	-1.8	-2.6	-1.5	-1.8	-1.9	-2.1
Alcohol intake versus 10 years previously	2.5	3.8	11.3	-1.9	0.7	-2.5	-1.7	-1.7	-2.5	-0.8	-1.8	-3.4	-0.7	-1.9	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.1	9.7	1.6	-0.8	3.1	2.5	0.3	3.0	2.7	2.5	2.5	1.7	2.2	2.2
Medication for pain relief, constipation, heartburn	2.3	4.0	6.6	-1.6	0.9	-1.5	-2.4	-1.2	-2.5	-1.1	-2.4	-2.1	-2.6	-2.1	-2.5
Diabetes (mother)	2.2	2.8	7.2	-1.4	0.8	-1.7	-2.0	0.9	-2.7	-0.4	-1.7	-1.0	-2.1	-2.1	-1.7
Pack years adult smoking proportion	2.2	3.4	6.4	-1.9	-1.9	-2.1	-1.9	-0.8	-1.5	-1.6	-2.5	-1.4	-1.9	-1.8	-2.1
High blood pressure	2.2	6.1	16.4	-1.3	1.1	-2.0	-2.8	0.1	-3.1	-1.5	-2.2	-2.1	-4.0	-3.0	-3.5
Medication: Atenolol	2.2	2.8	8.4	-1.3	-0.3	-1.6	-2.0	-0.6	-1.9	-1.8	-1.7	-1.1	-2.9	-1.4	-1.8
Age at first live birth	2.2	3.8	7.9	2.3	-0.0	2.2	2.2	-0.9	2.6	-0.0	2.1	1.6	2.8	2.1	2.0
Peak expiratory flow (PEF)	2.1	4.9	15.3	1.4	-0.7	2.1	2.3	2.0	3.5	1.8	1.9	3.9	1.4	2.0	1.6
Loud music exposure frequency	2.1	2.3	4.0	1.4	-1.0	1.8	1.4	0.5	1.5	0.8	1.8	1.7	1.4	2.0	2.0
Medication: Atorvastatin	2.1	2.6	6.5	-1.5	-1.4	-2.6	-1.9	-1.2	-1.5	-0.9	-1.8	-1.3	-1.2	-1.5	-1.8
Ever had hysterectomy (womb removed)	2.0	2.2	6.0	-2.4	-2.2	-1.1	-1.3	0.6	-1.3	-2.2	-1.2	-1.7	-1.1	-0.7	-0.5
Standing height	2.0	20.0	30.9	2.2	1.1	5.6	5.3	2.5	5.0	4.7	4.7	5.5	3.6	5.5	5.1
Illnesses of father: Heart disease	1.9	2.7	7.9	1.8	-1.3	2.0	1.2	2.0	2.0	0.4	1.6	2.8	1.0	0.7	1.1
Length of working week for main job	1.8	2.0	6.6	-2.6	0.2	-1.0	-1.3	-0.6	-1.6	-1.5	-1.2	-1.2	-1.3	-1.7	-1.3
Number of full sisters	1.8	2.2	4.7	0.7	1.2	0.7	2.0	1.7	0.8	1.9	1.4	0.9	1.5	2.2	1.9
Knee pain experienced in last month	1.8	2.9	7.0	-1.9	-1.1	-1.8	-2.2	0.0	-2.6	-1.6	-2.0	-1.8	-0.9	-1.4	-1.5
Hypertension (Self-reported)	1.8	5.0	14.3	-0.8	1.5	-1.9	-2.4	0.1	-3.0	-1.4	-1.9	-2.0	-3.8	-2.4	-2.9
Vascular/heart problems diagnosed by doctor	1.8	4.9	14.6	1.5	-0.6	1.9	2.5	-0.9	2.7	1.2	1.9	1.4	3.8	2.6	3.2
Bipolar Disorder (2018)	1.7	2.7	5.4	1.1	1.4	0.7	1.9	0.8	2.0	2.3	1.8	1.8	1.1	2.3	1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.8	7.7	1.4	-1.2	2.3	2.1	0.3	2.7	2.0	2.0	2.8	1.2	2.2	1.9
Falls in the last year	1.7	2.3	6.2	-1.6	-0.1	-1.2	-1.6	-0.8	-2.4	-1.4	-1.7	-2.5	-1.1	-1.0	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	3.8	0.2	0.8	1.1	1.6	1.3	1.4	2.0	1.8	1.1	1.6	1.7	1.8
Rheumatoid Arthritis	1.5	2.1	4.4	-0.4	0.3	-2.1	-1.8	-0.6	-1.4	-0.9	-2.1	-1.2	-1.7	-1.6	-1.8
Heel T-Score	1.5	12.1	33.5	2.6	-2.0	2.2	3.7	-1.4	5.8	3.6	3.8	4.6	3.4	3.4	2.9
Noisy workplace	1.5	1.8	4.8	1.2	0.7	0.5	1.5	1.1	0.9	0.9	1.1	1.9	1.6	2.2	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.9	12.0	1.6	0.5	2.6	2.5	1.7	3.2	1.7	1.8	3.5	1.6	2.3	1.8
Worry too long after embarrassment	1.5	2.6	6.5	1.0	-1.5	1.7	1.5	0.2	1.4	-0.6	2.2	1.4	1.8	2.0	2.6
Unable to work because of sickness or disability	1.5	1.9	5.9	-0.5	-1.0	-1.7	-1.5	-0.6	-1.6	-0.2	-1.3	-2.4	-1.2	-1.7	-1.4
Ulcerative Colitis (UC)	1.4	2.6	6.1	1.6	-0.8	1.8	1.4	2.5	1.2	0.5	1.4	2.0	1.0	1.9	1.9
Smoking Status	1.4	3.3	6.5	0.7	-1.8	0.9	1.9	2.2	1.6	0.9	2.0	2.1	1.7	2.5	2.3
Birth weight of first child	1.4	2.6	5.7	1.2	-0.6	1.9	1.8	-0.6	2.4	-0.8	1.5	1.3	2.4	1.8	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	3.3	-0.3	-0.1	-1.5	-1.5	0.5	-1.6	-0.8	-0.8	-1.6	-1.8	-1.8	-1.7
Family relationship satisfaction	1.4	1.8	4.5	-0.5	-2.1	-1.2	-1.3	-0.7	-1.4	-1.6	-1.3	-1.6	-0.8	-1.3	-1.3
Medication: Blood pressure	1.4	2.6	8.3	-0.4	0.6	-1.2	-1.8	0.6	-2.2	-1.3	-1.1	-1.6	-2.9	-1.7	-2.1
Verbal and Numeric Reasoning (VNR)	1.3	3.2	11.0	-1.4	-1.3	-1.0	-2.1	1.9	-1.8	-3.3	-1.7	-0.7	-1.7	-1.9	-1.5
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	3.4	1.1	-0.7	1.0	1.1	1.0	1.5	0.5	1.0	1.8	1.3	1.4	1.2
Mouth/teeth dental problems	1.3	2.0	5.4	-1.0	-0.7	-1.4	-1.6	-2.0	-0.6	-1.1	-1.6	-0.9	-0.4	-2.3	-1.8
Worrier / anxious feelings	1.3	2.5	4.7	2.0	-0.4	1.8	1.6	-0.3	1.5	-0.7	2.1	1.3	1.5	2.1	2.2
Impedance of arm (left)	1.3	6.1	9.8	2.8	-0.3	3.0	2.8	-0.1	3.1	2.8	2.1	2.9	2.1	2.6	2.3
Medication: Ibuprofen	1.3	1.6	5.3	1.8	-0.6	0.9	1.4	-1.3	1.5	0.2	1.0	0.1	2.3	1.1	1.2
Commuting to job workplace: Walk	1.3	1.4	4.1	2.0	0.3	0.5	1.3	0.2	1.1	0.3	1.1	0.8	1.8	1.7	1.2
Alcohol drinker status: Never	1.3	1.5	4.4	1.3	2.1	1.7	1.2	0.8	1.0	0.6	1.4	0.9	1.3	0.6	1.1
Bipolar Disorder or Schizophrenia	1.2	2.9	5.1	1.9	0.7	1.1	2.0	0.0	2.3	1.7	2.2	1.3	1.7	2.0	2.0
Fasting Glucose	1.2	1.4	3.3	-0.5	-1.1	-1.4	-1.6	-1.4	-1.0	-1.8	-1.2	-0.3	-1.4	-0.6	-1.1
Hearing difficulty/problems: Yes	1.2	1.9	4.5	-1.2	1.0	-2.1	-2.0	-0.8	-1.5	-0.8	-1.4	-0.7	-1.2	-1.6	-1.3
Forced expiratory volume in 1-second (FEV1)	1.2	3.9	9.9	1.5	0.2	2.4	2.3	1.3	3.0	0.9	1.7	3.1	1.3	2.1	1.6
Medication: Amlodipine	1.2	1.7	3.9	0.6	0.6	-0.9	-1.4	0.3	-1.5	-1.4	-1.1	-1.3	-1.6	-1.8	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	10.6	0.6	-1.4	-0.3	-0.8	0.8	-1.6	-3.3	-0.3	-1.4	-0.6	-0.3	-0.1
Angina (self-reported)	1.2	1.6	9.1	-1.9	-3.0	-0.3	-0.9	0.9	-0.1	-1.5	-0.6	0.3	-0.6	-0.8	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	8.0	-0.2	0.3	-0.6	-0.2	2.8	-0.2	1.3	-0.9	2.1	-1.1	0.0	-0.6
Illnesses of siblings: Diabetes	1.2	1.4	3.2	0.4	1.2	-0.9	-0.7	-1.8	-1.7	0.2	-1.4	-1.3	-1.5	-0.6	-1.3
Ever had bowel cancer screening	1.2	1.4	5.0	-1.3	-0.7	-1.1	-1.4	-0.9	-0.9	-2.2	-1.1	-1.1	-0.5	-1.0	-0.9
Medication for cholesterol	1.2	1.8	4.8	1.6	0.1	1.4	1.3	0.5	1.2	1.1	0.9	1.3	2.2	1.4	1.8
Mineral and other dietary supplements	1.2	1.7	4.1	0.8	-0.5	1.3	1.4	2.0	1.6	1.3	1.3	1.0	1.2	1.2	1.3
Angina	1.1	1.4	7.1	-1.9	-2.7	-0.5	-0.9	0.9	-0.1	-1.4	-0.6	0.4	-0.6	-0.7	-0.9
Supplements: Glucosamine	1.1	1.4	7.7	-0.9	-0.3	-0.7	-1.2	-2.8	-0.7	-0.7	-1.2	-0.7	-0.3	-1.1	-1.3
Medication: Levothyroxine sodium	1.1	1.8	5.6	-0.5	1.4	-2.4	-1.3	1.3	-2.0	-0.8	-1.2	-0.8	-1.1	-1.3	-1.0
Mouth/teeth dental problems: Dentures	1.1	1.8	5.4	1.4	1.1	0.5	1.9	1.7	-0.0	0.9	1.6	0.2	0.2	2.3	1.8
High blood pressure (siblings)	1.1	1.6	3.6	-1.4	1.0	-1.5	-1.0	-1.9	-1.3	-0.7	-1.1	-1.4	-1.1	-1.2	-1.4
Wheeze or whistling in the chest in last year	1.1	1.9	6.0	-2.4	-0.3	-1.8	-1.7	0.0	-1.4	-1.0	-1.4	-0.3	-1.3	-1.3	-1.6
Medication: Allopurinol	1.1	1.5	6.0	-2.4	-0.3	-0.2	-0.8	-1.6	-1.2	-0.8	-1.2	-1.4	-0.7	-1.0	-1.2
Medication: Seretide 50 evohaler	1.1	1.3	3.6	-1.5	0.1	-1.1	-1.0	-1.8	-0.9	-0.3	-0.7	-1.9	-0.6	-1.1	-1.0
Mean time to correctly identify matches	1.1	2.1	3.8	1.3	-0.9	1.1	1.5	1.9	1.1	1.9	1.1	1.8	0.7	1.7	1.6
Risk taking	1.1	1.6	3.9	1.3	-1.6	0.3	1.1	1.3	1.3	-0.1	1.0	1.4	1.0	2.0	1.3
Impedance of whole body	1.1	5.8	12.5	2.8	-0.9	2.6	2.4	-0.6	3.4	2.6	1.9	3.5	1.6	2.6	2.1
Coronary Artery Disease (CAD)	1.0	1.2	4.9	-0.5	-2.2	-1.2	-1.4	1.0	-0.5	-1.4	-1.0	0.1	-0.9	-0.8	-0.6
Schizophrenia (2014)	1.0	2.3	4.7	1.7	-0.0	1.4	1.9	-0.0	1.8	0.9	2.2	0.8	1.7	1.7	2.1
Blood Red Count	1.0	9.2	31.1	1.5	-4.7	-0.4	0.9	4.5	4.2	-0.3	1.3	5.6	2.8	2.1	1.9
Medication: Co-codamol	1.0	1.2	2.8	-1.1	-0.1	-1.2	-1.3	0.6	-1.7	-0.9	-1.0	-1.1	-1.3	-1.0	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	3.0	1.7	-0.2	0.7	1.3	1.0	-0.2	0.2	1.4	-0.1	1.5	1.7	1.7
Impedance of arm (right)	1.0	4.8	8.3	2.8	-0.1	2.4	2.4	-0.4	2.8	2.2	1.9	2.9	1.8	2.4	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	4.4	1.1	-1.1	0.7	1.3	-1.0	1.3	-0.3	0.9	0.4	2.1	1.1	1.0
Gout (self-reported)	1.0	1.4	6.7	-2.6	-0.6	-0.3	-0.9	-1.0	-0.9	-0.7	-1.2	-0.8	-1.3	-0.7	-1.5
Birth weight	1.0	2.2	4.6	1.3	-0.2	1.7	2.0	-0.6	1.7	1.5	2.1	0.8	1.6	1.4	1.6
Migraine (self-reported)	1.0	1.2	4.0	-0.1	0.5	0.8	1.2	1.6	0.4	2.0	0.5	1.3	0.8	1.4	1.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.0	-0.8	-1.3	-1.3	-1.0	-0.2	-1.0	-1.4	-1.0	-1.2	-1.1	-1.1	-1.3
Medication: Bendroflumethiazide	1.0	1.5	4.4	-1.0	1.0	-0.4	-1.2	-0.1	-1.8	-1.0	-0.8	-1.5	-2.1	-1.3	-1.3
Waist Hip Ratio (WHR)	0.9	3.8	10.4	2.3	-1.2	1.9	1.6	2.7	2.2	-0.9	1.8	3.2	0.4	2.0	1.7
Impedance of leg (right)	0.9	4.5	11.2	2.7	-1.3	2.3	1.7	-1.5	3.2	1.5	1.6	3.3	1.0	2.0	1.5
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.5	0.4	0.3	-0.7	-1.3	-0.1	-1.3	-1.0	-1.1	-0.5	-1.6	-0.8	-1.1
Body mass index (BMI)	0.9	3.8	7.6	-2.6	-0.2	-2.2	-2.2	2.1	-2.8	-2.1	-1.6	-2.0	-1.4	-1.5	-1.3
Alcohol usually taken with meals	0.9	1.5	3.8	-0.0	0.4	1.3	0.9	-1.4	1.8	1.9	1.3	0.4	1.7	0.6	0.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.7	-1.0	0.8	-0.2	-1.1	-1.0	-1.4	-0.4	-0.7	-1.7	-1.5	-1.3	-1.2
Pulse rate	0.9	1.6	3.1	1.3	0.2	1.0	1.5	0.1	1.8	0.8	1.7	1.5	1.5	1.2	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	6.4	0.0	-0.5	-0.6	-1.0	-1.2	-1.5	-2.5	-0.4	-1.7	-1.2	-0.6	-0.3
Health satisfaction	0.9	1.2	3.2	-1.8	-1.5	-1.2	-1.1	-1.1	-0.7	-0.8	-0.8	-1.6	0.6	-0.4	-0.2
Emphysema/chronic bronchitis	0.9	1.0	3.1	0.2	0.1	-0.8	-1.0	0.5	-1.2	-1.0	-0.8	-0.7	-1.8	-1.2	-1.3
Reaction Time	0.8	1.5	2.5	1.3	-1.0	1.2	1.5	1.4	1.4	1.2	0.9	1.6	0.5	1.3	1.2
Ovarian Cancer	0.8	1.1	4.3	0.2	-0.1	0.9	0.6	0.5	2.0	0.1	0.6	0.8	2.1	1.0	1.2
Serious illness, injury or assault to yourself	0.8	0.9	1.9	-1.0	-1.2	-1.4	-1.0	1.0	-0.9	-0.4	-0.9	-1.4	-0.5	-0.6	-0.7
Chronic bronchitis/emphysema (father)	0.8	1.0	2.5	-1.3	-1.6	-0.5	-0.8	-1.4	-1.3	-0.5	-1.3	-1.0	0.4	-0.1	-0.6
High blood pressure (mother)	0.8	1.1	3.1	-0.0	-0.1	-0.5	-0.9	-0.5	-0.9	-1.8	-0.5	-0.6	-1.7	-1.4	-1.7
Impedance of leg (left)	0.8	4.0	12.6	2.4	-1.3	1.9	1.6	-1.3	3.2	1.6	1.4	3.6	0.6	2.0	1.3
Medication: Paracetamol	0.8	1.3	2.8	1.2	-0.4	0.5	1.3	0.5	1.4	0.9	1.3	0.8	1.7	1.1	1.6
Loneliness, isolation	0.8	1.2	2.5	1.2	1.1	1.4	0.9	1.6	0.3	-0.2	1.2	-0.1	1.3	1.0	1.4
Medication: Gliclazide	0.8	0.9	3.6	0.5	0.5	0.1	-0.8	-1.7	-0.5	-0.9	-0.8	-1.9	0.4	-0.5	-0.6
Myopia	0.8	1.2	3.2	-1.8	-1.0	-0.2	-0.8	0.9	-0.9	-1.5	-1.3	-0.6	-1.0	-0.9	-1.3
Supplements: Calcium	0.8	0.9	5.3	1.0	-0.2	-0.1	-0.5	1.0	-1.1	-2.3	-1.0	-0.1	-0.9	-0.4	-0.4
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.6	-2.4	-1.4	-0.8	-0.5	0.8	-0.3	-0.5	-0.2	0.7	-1.1	-0.5	-0.6
Schizophrenia vs Biploar Disorder	0.7	0.9	4.0	-0.5	-1.7	0.3	-0.8	-0.7	-0.6	-2.0	-0.7	-0.4	-1.0	-0.3	-0.5
Bipolar Disorder (2011)	0.7	0.7	6.4	0.5	2.5	-0.4	0.4	-0.2	-0.1	1.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.7	0.8	2.5	-1.2	-1.6	-0.2	-1.4	-0.6	-0.5	-0.6	-0.5	-0.6	-0.4	-1.2	-0.9
Cardiovascular Disease	0.7	2.4	8.4	-1.0	0.8	-1.4	-1.5	0.6	-1.5	-0.5	-1.0	-0.8	-2.9	-1.9	-2.5
Lung FEV1/FVC ratio	0.7	3.5	16.2	0.7	2.4	1.2	1.8	0.8	1.2	4.0	1.6	0.4	1.9	1.7	1.9
Chronotype (morning person)	0.7	1.5	4.3	2.1	-0.3	1.1	1.3	-0.3	2.0	-0.6	1.8	0.5	1.4	0.7	0.9
Average weekly spirits intake	0.7	0.8	2.9	-1.7	-0.2	-1.0	-1.1	-0.6	-0.8	-0.6	-0.6	-0.8	-1.4	-0.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.9	0.8	0.5	0.2	0.8	1.7	0.2	0.2	1.0	0.2	1.6	1.0	1.4
Hayfever, allergic rhinitis or eczema	0.7	1.5	2.9	-0.3	0.8	1.6	1.5	0.6	1.3	1.4	1.7	0.9	1.7	0.7	1.3
Number of incorrect matches in round	0.7	1.1	3.6	-0.9	-1.9	0.2	-0.6	-0.8	-0.9	-1.7	-0.9	-0.9	-1.3	-0.4	-0.8
Forced vital capacity (FVC)	0.7	2.6	7.4	1.4	-0.4	2.2	1.9	0.6	2.7	-0.1	1.2	2.7	0.8	1.8	1.0
Heart attack	0.7	1.0	5.3	-2.3	-1.3	-0.7	-0.6	0.8	-0.4	-0.4	-0.3	0.8	-1.2	-0.6	-0.6
Fluid intelligence score	0.7	1.4	3.6	-0.7	-0.0	-0.1	-1.4	1.6	-1.2	-1.9	-1.0	-0.3	-1.7	-1.3	-1.0
Illnesses of siblings	0.7	1.0	6.8	1.0	-1.1	0.2	0.0	2.6	0.9	0.1	0.3	1.1	0.3	0.3	0.7
Time employed in main current job	0.7	0.8	2.4	-0.7	0.9	1.6	0.6	1.4	0.4	1.1	0.5	0.8	0.0	0.9	0.5
Illnesses of mother	0.7	0.8	1.8	-0.3	1.1	0.0	0.5	-0.8	1.3	1.4	0.9	0.3	1.4	0.9	1.0
Hair/balding pattern: Pattern 4	0.7	1.7	3.7	0.1	-0.0	1.4	1.1	1.2	1.3	1.4	1.5	1.9	1.0	1.4	1.6
Forced vital capacity (FVC), Best measure	0.7	2.5	8.4	1.6	-0.5	2.0	1.7	0.8	2.6	0.3	0.9	2.9	0.9	1.6	0.8
Number of full brothers	0.7	0.9	1.8	0.4	-1.1	0.8	1.3	-0.1	0.5	0.8	1.0	1.3	0.6	1.3	1.2
Heart disease (mother)	0.7	0.9	2.4	-0.6	-0.8	-1.5	-0.9	0.5	-0.7	-0.3	-1.3	-0.2	-1.0	-0.9	-1.3
Comparative height size at age 10	0.7	4.0	9.4	0.3	0.6	2.7	2.1	1.9	1.9	3.1	1.6	2.5	1.2	2.3	1.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.8	1.0	1.7	1.3	0.4	-1.4	0.5	1.3	0.7	0.1	-0.1	-0.3	-0.2
Average weekly red wine intake	0.7	1.0	3.0	1.2	-0.7	1.7	0.8	-1.7	1.0	0.6	1.0	-0.6	0.9	-0.1	0.6
Average weekly beer plus cider intake	0.7	1.1	3.7	0.8	1.1	1.1	1.5	0.4	1.2	0.1	0.7	1.9	0.5	1.0	0.5
Irritable Bowel Disease (IBD)	0.6	1.5	3.5	0.8	-0.3	1.6	1.0	1.9	0.7	0.5	1.0	1.3	0.6	1.6	1.9
Major Depression (MDD)	0.6	0.8	3.8	-0.4	0.7	0.3	-0.3	-1.9	-0.8	-1.5	-0.1	-1.0	0.5	-0.2	0.4
Mean Putamen Volume	0.6	0.7	2.3	-0.1	-1.3	0.5	0.6	1.1	0.2	0.9	0.3	0.2	1.5	0.8	1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.3	0.5	-0.7	-0.2	0.4	0.3	0.4	0.7	1.0	-0.2	1.4	1.0	1.5
Ulcerative Colitis	0.6	0.9	3.2	0.7	-0.2	0.7	0.5	1.8	0.9	0.5	0.3	1.3	1.1	0.9	1.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	4.0	-2.0	-1.3	-1.0	-0.9	0.9	-0.8	-0.4	-0.6	0.2	-0.1	-0.1	-0.1
Medication: Lansoprazole	0.6	0.7	2.0	-1.4	-0.1	-0.7	-0.3	1.3	-1.0	0.3	-1.1	0.6	-1.0	0.2	-0.6
Blood clot in the leg (DVT)	0.6	0.8	4.0	-0.7	-2.0	-0.5	-0.8	0.1	-0.7	0.6	-0.6	-1.1	-0.5	-0.8	-0.6
Comparative body size at age 10	0.6	1.6	6.6	-1.6	-1.1	-1.6	-0.7	-1.3	-1.0	-0.8	-0.5	-2.6	0.1	-1.2	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.7	0.5	0.4	-0.3	-0.4	1.6	-1.6	-0.7	-0.4	-0.1	-0.8	0.7	0.3
Suffer from ‘nerves’	0.6	0.9	2.1	0.2	-0.7	-0.7	-1.0	-0.6	-1.2	-1.2	-1.1	-1.4	-1.4	-0.5	-0.6
Chest pain or discomfort	0.6	0.8	1.4	-1.0	-1.0	-1.1	-1.0	1.0	-1.2	0.8	-1.0	0.0	-0.8	-0.5	-0.7
Had major operations	0.6	0.7	4.0	-0.0	-2.0	-0.0	-0.7	-0.8	0.4	-0.9	-0.3	-0.3	0.4	-1.1	-0.8
Supplements: Vitamin C	0.6	0.7	5.4	1.2	0.6	-0.1	0.2	-2.3	0.5	-0.1	0.4	-0.3	0.6	-0.0	0.2
Average weekly champagne plus white wine intake	0.6	0.9	3.2	1.3	-1.8	0.7	-0.0	1.3	0.4	0.0	0.6	1.1	0.3	0.7	1.1
Diastolic blood pressure, automated reading	0.6	1.8	3.1	0.6	0.3	-1.6	-1.5	1.3	-1.7	-1.4	-0.9	0.1	-1.7	-1.8	-1.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	4.1	-0.7	-2.0	-0.6	-0.8	0.3	-0.6	0.5	-0.6	-0.8	-0.6	-0.8	-0.6
Heart disease (siblings)	0.6	0.7	2.1	0.0	-0.5	1.5	0.7	-0.6	0.3	0.7	0.7	0.2	1.1	1.1	1.1
Schizophrenia (2018)	0.5	1.1	2.4	1.5	-1.0	0.8	1.0	-0.6	1.3	0.4	1.4	0.3	1.4	0.8	1.3
Alzheimer’s Disease (in mother)	0.5	0.6	4.2	-0.4	-2.0	0.6	-0.3	0.5	0.5	0.3	-0.4	1.0	0.7	-0.2	0.2
Breast Cancer	0.5	1.1	4.8	-1.4	2.2	-0.4	-0.4	-0.6	-0.5	-0.7	-1.1	-0.9	0.2	-1.2	-1.2
Prostate Cancer	0.5	0.7	1.3	0.1	0.2	-1.0	-1.1	-0.9	-0.7	0.1	-0.9	-0.8	-0.7	-1.0	-1.1
Triglycerides	0.5	0.7	4.8	-0.5	0.5	-0.3	-0.2	-1.5	0.1	-2.2	-0.2	-0.4	-0.8	-0.5	-0.4
BMI	0.5	2.8	5.6	-2.4	-0.7	-1.8	-1.7	2.0	-2.2	-1.4	-1.4	-2.1	-0.9	-1.4	-1.1
Supplements: Zinc	0.5	0.5	1.1	0.1	-0.6	0.8	1.0	0.4	0.4	0.6	0.7	0.6	0.7	0.9	1.1
Medication: Metformin	0.5	0.8	5.0	-0.4	-0.1	-0.2	-1.0	-0.4	-0.5	-1.0	-0.5	-2.2	-0.3	-0.8	-0.7
Had menopause	0.5	0.7	3.9	0.4	-0.0	0.3	0.6	2.0	0.1	0.4	0.5	1.2	-0.5	1.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.6	-0.6	0.1	-1.1	-0.9	-1.0	-1.3	-0.5	-0.5	-0.9	-0.3	0.1	0.4
Medication: Simvastatin	0.5	0.8	2.6	0.2	0.4	1.6	0.7	1.6	1.1	0.0	1.2	0.6	0.4	0.4	0.4
Neuroticism score	0.5	0.9	2.5	1.2	-1.0	0.8	0.7	0.6	0.4	-0.8	1.1	0.7	1.0	1.3	1.6
Father’s age at death	0.5	0.7	2.5	-0.6	-1.1	-0.9	-0.3	1.0	-0.8	-1.0	-0.4	-1.6	-0.1	0.1	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.1	0.4	-1.8	-0.2	-0.4	1.5	-1.3	-1.2	-0.5	0.1	-0.1	0.1	0.7
Hair/balding pattern: Pattern 3	0.5	0.7	6.2	2.5	0.2	-0.8	0.2	-0.2	0.2	0.3	0.7	-0.0	0.9	-0.3	0.0
Medication: Cholesterol lowering	0.5	0.8	1.6	-1.2	-0.6	-0.5	-1.1	-0.6	-0.6	-0.6	-0.5	-1.3	-0.9	-1.2	-1.0
Depression (self-reported)	0.5	0.5	1.4	1.2	-1.1	0.9	0.6	-0.2	0.1	-0.2	0.6	-0.4	0.9	0.8	0.9
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.9	0.3	1.0	0.5	-0.2	-1.6	-0.2	0.5	-0.1	-1.7	0.3	-1.1	-0.6
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.6	-1.1	0.7	-0.2	-0.2	-1.6	0.1	-0.7	-0.0	-1.1	-0.5	-0.8	-0.6
Alcohol intake frequency.	0.5	1.1	4.8	-0.6	1.7	-0.8	-0.8	0.5	-1.7	0.3	-0.3	-2.2	-0.2	-0.7	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.4	-1.0	-0.9	-0.5	-1.2	0.1	-0.8	-0.9	-1.1	-1.1	-1.0	-0.7	-0.9
Back pain experienced in last month	0.5	0.7	2.0	1.4	0.6	0.9	1.0	-0.3	0.5	0.7	0.8	0.4	0.7	1.2	0.9
Osteoarthritis (self-reported)	0.5	0.6	2.0	-1.4	0.5	-1.0	-1.0	-1.0	-0.5	1.0	-0.9	-0.4	0.0	0.1	-0.1
Wears glasses or contact lenses	0.5	0.6	2.0	0.3	-1.4	0.0	0.2	1.4	0.2	0.8	0.1	-0.1	1.0	0.8	0.7
Hearing aid user	0.5	0.5	2.5	-0.3	1.6	-1.4	-0.4	1.2	-0.3	0.2	-0.2	0.3	-0.0	-0.1	-0.2
Medication: Paracetamol	0.5	0.7	1.9	1.4	-0.1	0.7	0.8	-0.2	1.1	0.8	1.0	0.3	1.0	0.8	1.0
Leg fat percentage (left)	0.5	1.8	3.9	-1.7	-1.1	-1.5	-1.6	1.6	-1.3	-2.0	-0.9	-0.7	-1.3	-0.9	-0.9
Irritability	0.5	0.9	3.5	0.2	1.0	-1.9	-1.0	-0.4	-1.6	0.6	-0.9	-0.4	-0.4	-1.0	-0.5
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.6	-0.9	-0.3	-0.6	-0.9	-1.3	-0.4	-0.9	-0.7	-0.5	-0.3	-1.0	-0.9
Alzheimer’s Disease (including proxy)	0.4	0.5	4.1	-0.5	-2.0	0.6	-0.4	0.6	-0.0	-0.5	-0.5	0.7	-0.3	0.0	0.0
Crohns Disease (2012)	0.4	0.6	1.9	0.3	-0.1	0.5	0.9	0.2	0.8	0.5	0.5	0.5	1.2	0.9	1.4
Lupus	0.4	0.7	3.0	1.7	1.6	1.0	0.3	-0.3	0.3	0.5	0.6	0.6	-0.0	0.5	0.4
Blood White Count	0.4	2.7	4.4	-2.0	-2.0	-2.0	-2.1	1.2	-1.3	-1.4	-1.9	0.1	-1.4	-1.7	-1.5
Allergy or Eczema	0.4	0.9	3.4	-1.9	0.6	1.4	0.8	0.6	0.3	1.3	1.0	0.7	0.9	0.1	0.8
Hypothyroidism (self reported)	0.4	0.8	2.8	-0.3	0.9	-1.7	-0.5	0.9	-1.6	-0.6	-0.5	-0.1	-0.9	-0.8	-0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.6	-0.2	-1.0	-0.9	-0.7	0.0	-1.3	-0.5	-0.5	-1.1	0.4	-0.5	-0.0
Hand grip strength (right)	0.4	1.1	5.3	-0.3	-1.5	0.1	0.7	1.2	1.1	-0.2	0.6	2.3	-0.2	0.9	0.7
Current tobacco smoking	0.4	0.6	2.8	-1.1	-1.7	-1.4	0.3	0.8	-0.2	-0.0	-0.1	0.2	-0.2	0.5	0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.6	-1.6	-1.0	-0.4	-0.4	-0.4	-0.4	-0.2	-0.3	-0.8	0.0	-0.2	-0.3
Sitting height	0.4	2.7	6.2	-0.8	0.1	2.3	2.3	0.5	1.4	1.0	1.8	1.4	1.2	2.2	2.5
Nervous feelings	0.4	0.8	4.6	0.7	-2.1	0.2	0.0	-0.4	0.2	-1.4	0.7	0.6	0.2	0.4	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.7	-0.6	-1.6	-0.5	-0.5	0.6	-1.2	-1.0	-0.3	-0.8	-0.0	-0.0	0.2
Hair/balding pattern: Pattern 2	0.4	0.6	2.3	-0.9	0.7	1.1	0.5	1.5	0.1	0.2	0.1	0.3	-0.5	1.1	0.4
Allergy	0.4	0.9	2.0	0.1	-1.1	-1.2	-0.9	-0.8	-0.7	-0.8	-1.4	-0.4	-1.2	-0.5	-1.1
Happiness	0.4	0.5	1.5	0.1	0.1	0.4	0.8	1.1	0.1	0.4	0.6	0.2	0.7	0.9	1.2
Lung cancer (father)	0.4	0.5	1.1	-1.0	-0.3	-1.0	-0.6	-0.9	-0.7	-0.4	-1.1	-0.5	-0.4	-0.6	-0.7
Leg fat percentage (right)	0.4	1.6	3.7	-1.6	-1.2	-1.3	-1.6	1.3	-1.3	-1.9	-0.9	-0.9	-1.1	-0.9	-0.8
Neck or shoulder pain in last month	0.4	0.5	2.1	0.8	-0.6	0.1	0.6	-1.4	0.2	-0.3	0.5	-0.0	1.3	0.3	0.7
Long-standing illness, disability or infirmity	0.4	0.6	2.2	-0.2	0.5	-1.3	-0.5	1.0	-0.9	0.2	0.1	-1.5	0.6	-0.0	0.7
Diabetes diagnosed by doctor	0.4	0.7	4.4	-0.6	0.4	-0.2	-0.9	-0.4	-0.7	-0.5	-0.4	-2.1	-0.3	-0.8	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	2.2	-1.5	-0.2	-0.6	0.3	0.1	0.6	-0.2	0.5	0.3	0.2	1.1	0.7
Osteoporosis (self-reported)	0.4	0.4	1.5	0.6	-1.2	0.2	-0.3	0.7	0.9	-1.1	-0.1	0.9	0.2	-0.4	-0.1
Medication: Aspirin	0.4	0.5	1.0	0.7	-0.2	0.7	0.6	1.0	0.7	0.8	0.9	0.1	0.6	0.5	0.6
Miserableness	0.4	0.8	2.4	0.9	-0.8	0.6	-0.0	1.6	-0.5	-1.5	0.3	0.8	0.3	0.6	1.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.5	0.9	1.5	0.2	0.0	1.6	-0.4	0.5	0.1	-0.0	0.4	0.1	-0.3
Age started oral contraceptive pill	0.4	0.5	2.2	0.6	0.8	1.0	0.3	-1.5	-0.4	0.3	0.4	-1.0	0.1	0.1	0.2
Ever depressed for a whole week	0.4	0.5	1.3	-1.1	-0.1	-1.0	-0.8	-0.8	-0.9	0.1	-0.2	-1.0	0.2	-0.4	0.2
Commuting to job workplace: Cycle	0.4	0.5	1.2	0.4	0.6	0.8	0.8	-0.5	-0.2	-0.5	0.7	-0.5	0.7	0.8	1.1
Alcohol drinker status: Previous	0.4	0.5	0.9	-0.6	0.9	-0.9	-0.8	0.8	-0.9	0.6	-0.3	-0.7	-0.4	-0.5	-0.1
Depressed Affect (Nagel 2018)	0.3	0.6	1.7	0.6	-0.9	-0.6	-1.0	1.3	-0.8	-1.1	-0.4	0.2	-0.5	-0.7	-0.4
Depression (Nagel 2018)	0.3	0.5	1.8	1.0	-0.3	0.4	0.4	1.3	0.1	0.5	0.8	0.0	0.9	0.6	0.7
Neuroticism (Nagel 2018)	0.3	0.6	3.5	0.4	-1.9	0.1	-0.5	1.0	-0.4	-1.2	0.3	0.6	-0.0	-0.1	0.3
Worry (Nagel 2018)	0.3	0.7	3.8	0.0	-2.0	0.3	-0.2	-0.5	0.3	-1.9	0.3	0.4	-0.2	-0.0	0.0
Alzheimer’s Disease (in father)	0.3	0.4	1.1	1.0	-0.3	1.0	0.5	0.2	0.5	-0.2	0.9	0.4	-0.3	0.7	0.5
Age at First Birth	0.3	0.4	1.1	0.5	0.5	1.0	0.4	-0.4	1.0	0.9	0.4	0.4	0.9	0.3	0.3
HDL Cholesterol	0.3	0.5	2.8	0.6	-1.7	-0.7	-0.4	-0.5	0.4	1.0	-0.4	-0.0	0.4	-0.8	-0.4
LDL Cholesterol	0.3	0.5	3.1	-0.5	-0.3	0.8	-0.2	-1.8	0.2	-0.3	-0.0	-1.0	-0.1	-0.3	-0.3
Type 2 Diabetes (T2D) (2018)	0.3	0.6	3.4	-1.1	-0.2	-0.1	-0.9	-0.3	-0.2	0.2	-0.3	-1.9	0.3	-0.8	-0.3
Lung FVC	0.3	1.6	7.5	0.6	-0.9	-0.7	-1.2	-0.5	0.2	-2.7	-1.5	0.7	-1.3	-1.1	-1.8
Neuroticism	0.3	0.7	1.5	0.9	-1.1	0.7	0.5	1.0	0.2	-1.2	0.8	0.6	0.6	0.9	0.9
Hand grip strength (left)	0.3	0.8	3.5	0.2	-1.3	0.3	0.8	0.8	1.1	-0.7	0.6	1.9	0.1	0.8	0.3
Relative age of first facial hair	0.3	0.7	6.4	-0.4	2.5	0.9	-0.3	0.3	-0.6	-0.2	0.2	-0.5	-0.3	-0.3	-0.0
Medication for hormone replacement therapy	0.3	0.3	0.9	-0.0	0.1	0.4	0.8	-0.3	0.6	0.2	1.0	0.9	0.4	0.2	0.5
Vitamin and mineral supplements	0.3	0.5	1.9	-1.2	-0.2	-0.1	-0.1	1.4	-0.1	-0.5	-0.4	-0.0	-0.9	-0.4	-0.9
Diabetes (father)	0.3	0.4	1.8	0.5	-1.4	-0.1	-0.4	0.4	-0.2	-0.3	-0.1	-0.9	-0.1	-0.8	-0.4
Leg fat-free mass (left)	0.3	1.8	8.0	-1.1	1.1	1.3	1.2	2.8	0.1	0.6	1.3	0.3	1.1	1.3	1.6
Townsend deprivation index at recruitment	0.3	0.4	1.1	-0.3	0.4	-0.6	0.5	0.6	-0.9	0.2	0.2	-0.5	0.7	0.7	1.0
Maternal smoking around birth	0.3	0.4	1.1	-0.1	0.4	-1.0	-0.4	0.9	-0.2	-0.6	-0.2	-1.0	0.2	-1.0	-0.3
Fed-up feelings	0.3	0.6	1.5	-0.3	-1.0	-0.7	-0.9	0.8	-1.2	-1.2	-0.8	-0.4	-0.5	-0.5	-0.4
Qualifications: CSEs or equivalent	0.3	0.3	1.6	-0.8	-1.2	0.4	0.3	-0.5	0.6	-0.5	0.1	0.7	-0.3	0.2	-0.1
Stomach or abdominal pain in last month	0.3	0.3	1.1	-0.8	0.2	-0.8	-0.1	0.3	-0.7	-1.1	-0.4	0.0	-0.7	0.5	0.2
Leg predicted mass (left)	0.3	1.7	7.7	-1.2	1.1	1.2	1.1	2.8	0.0	0.6	1.2	0.3	1.1	1.2	1.6
Trunk fat mass	0.3	1.3	6.8	-0.8	-0.2	0.9	0.7	2.6	0.5	0.7	1.1	0.9	1.0	1.2	1.3
Waist circumference	0.3	1.2	10.2	-1.5	-0.4	-0.5	-0.4	3.2	-0.7	-0.9	-0.1	0.3	-0.4	0.4	0.2
Hearing difficulty/problems with background noise	0.3	0.6	3.9	0.9	2.0	0.6	0.3	-0.5	0.3	0.0	0.7	-0.3	0.7	-0.0	0.4
Had other major operations	0.3	0.4	1.2	0.4	-0.5	-0.1	-0.7	1.0	-0.9	-1.1	-0.7	-0.1	-0.5	-0.4	0.1
Medication: Ramipril	0.3	0.4	1.8	0.2	-0.5	-0.5	-0.3	0.9	-0.3	-0.4	0.0	0.3	-1.4	-0.7	-0.7
Trunk fat-free mass	0.3	2.0	4.9	-0.7	1.5	1.5	1.5	2.2	0.5	0.8	1.6	1.0	0.9	1.7	1.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.5	-0.9	1.2	-0.0	0.4	-0.5	-0.2	0.5	0.1	-0.1	0.7	0.7	0.6
Arm fat mass (right)	0.3	1.1	8.2	-1.5	-0.1	-0.5	-0.4	2.9	-1.1	-1.0	-0.1	-0.4	-0.2	0.2	0.3
Trunk predicted mass	0.3	2.0	5.2	-0.7	1.5	1.4	1.5	2.3	0.5	0.7	1.6	0.9	0.8	1.8	1.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.6	-0.6	1.3	-0.8	-0.6	-0.9	-0.8	-0.0	-0.1	0.1	0.3	-0.0	0.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.1	0.9	0.7	0.3	0.8	0.9	0.0	0.1	0.2	1.1	0.3	1.0	0.8
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.4	0.9	1.5	-0.5	0.1	1.3	-1.2	-0.1	0.3	-0.1	-0.0	-0.4	0.2
Exposure to tobacco smoke outside home	0.3	0.4	1.7	0.4	-0.0	0.0	-0.2	-0.3	-0.7	-1.3	0.2	-1.2	-0.8	0.2	-0.1
Number of children fathered	0.3	0.3	2.4	-0.6	-1.5	-0.7	-0.1	-0.4	0.3	0.1	-0.1	0.1	0.3	0.3	0.3
Whole body fat mass	0.3	1.1	8.6	-1.0	-0.0	0.4	0.3	2.9	-0.0	0.1	0.8	0.6	0.5	0.9	0.9
Overall health rating	0.3	0.7	1.9	-0.4	-1.0	-0.8	-0.8	0.6	-1.4	-0.7	-0.8	-1.4	-0.5	-0.2	-0.1
Leg pain on walking	0.3	0.4	1.8	-0.3	0.8	-0.0	-0.1	-1.3	-0.6	0.1	0.1	-0.9	0.6	0.1	0.0
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.5	0.9	-0.8	0.3	0.3	0.3	0.5	-0.3	0.2	1.2	-0.1	0.4	-0.2
Medication: Aspirin	0.3	0.4	1.1	0.5	-0.7	0.7	0.6	1.1	0.6	0.8	0.8	0.2	0.4	0.4	0.6
Whole body fat-free mass	0.3	1.8	6.6	-1.0	1.3	1.3	1.3	2.6	0.3	0.7	1.4	0.7	0.9	1.5	1.7
Leg fat-free mass (right)	0.3	1.6	7.4	-1.3	1.2	1.1	1.2	2.7	0.0	0.5	1.2	0.3	0.9	1.2	1.5
Friendships satisfaction	0.3	0.3	1.2	0.4	-1.1	0.7	0.4	0.6	0.1	-0.5	0.9	0.2	0.2	0.1	0.8
Qualifications: nursing, teaching	0.3	0.4	1.4	0.9	0.6	0.5	-0.2	1.1	-0.3	-1.2	0.3	0.3	0.1	0.3	0.6
Illnesses of father: None of the above (group 1)	0.3	0.3	1.3	-1.0	1.2	-0.7	0.3	0.2	-0.4	-0.5	-0.1	-0.7	0.3	0.1	0.3
Smoking status: Current	0.3	0.5	2.7	-1.1	-1.6	-1.3	0.2	0.3	-0.1	-0.1	0.0	-0.0	0.0	0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.1	1.2	0.6	0.5	0.8	0.2	1.4	-0.1	0.4	1.4	0.7	0.6	0.0
Whole body water mass	0.3	1.6	5.9	-1.1	1.3	1.2	1.2	2.4	0.2	0.7	1.4	0.5	0.8	1.4	1.6
Leg predicted mass (right)	0.3	1.6	7.5	-1.3	1.3	1.1	1.2	2.7	0.0	0.5	1.2	0.3	0.9	1.2	1.5
Financial situation satisfaction	0.3	0.4	1.2	-0.5	0.5	0.1	-0.5	-0.6	-1.1	0.9	-0.3	-0.8	0.4	-0.5	-0.2
Commuting to job workplace: Public transport	0.3	0.4	1.9	0.1	1.4	-0.0	0.3	-0.3	0.1	0.8	0.2	-1.0	1.0	0.0	0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.8	-0.3	0.7	-0.5	-0.7	-1.3	-0.8	-0.5	-0.3	-0.4	-0.2	-0.5	-0.5
Basal metabolic rate	0.3	1.6	7.2	-1.2	1.1	1.1	1.1	2.7	0.1	0.4	1.2	0.6	0.8	1.4	1.6
Cholesterol lowering medication	0.3	0.4	2.2	0.8	0.6	0.4	0.0	1.5	0.6	-0.6	0.6	0.2	-0.4	0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.0	-1.0	0.7	0.2	0.5	0.9	-0.1	1.4	0.1	0.3	0.4	0.1	0.2
Pain experienced in last month	0.3	0.4	1.6	-0.4	-0.4	0.5	0.6	-0.6	1.3	1.2	0.5	0.7	-0.1	0.1	0.1
Leg fat mass (left)	0.3	1.0	4.7	-1.8	-0.4	-0.6	-0.8	2.2	-1.0	-1.1	-0.2	-0.5	-0.5	-0.3	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.7	-0.2	-1.1	0.3	-0.3	1.6	0.1	-1.2	-0.3	0.6	-0.3	-0.2	0.1
Crohns Disease (2017)	0.2	0.5	1.4	0.2	0.8	1.2	0.8	0.1	0.3	0.4	0.7	-0.1	0.1	0.8	1.2
Primary Biliary Cirrhosis	0.2	0.3	1.1	-0.2	-0.8	0.6	0.3	-1.1	0.7	-0.2	0.6	0.5	0.5	0.4	0.6
Blood Eosinophil Count	0.2	1.2	5.4	-2.2	-2.3	-1.5	-0.6	-0.3	0.5	-0.5	0.1	0.8	-0.1	-0.3	0.3
Number of treatments/medications taken	0.2	0.3	2.2	-0.2	-0.3	-0.2	-0.6	-0.3	-0.1	-0.3	-0.1	-1.5	-0.2	-0.5	-0.5
Systolic blood pressure, automated reading	0.2	0.6	3.9	2.0	0.8	-0.0	-0.0	0.9	-0.1	0.8	0.7	0.6	-0.3	0.1	-0.0
Severe depression (siblings)	0.2	0.3	0.7	-0.5	-0.9	-0.6	-0.2	0.6	-0.5	-0.5	-0.3	-0.2	-0.0	0.8	0.5
Trunk fat percentage	0.2	0.9	6.3	-0.6	-0.5	0.6	0.3	2.5	0.4	0.5	0.8	0.8	0.7	1.0	1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.6	-0.6	0.7	-0.4	-0.4	-0.4	-0.5	-0.8	-0.1	-0.5	-0.0	0.2	-0.3
Financial difficulties in last 2 years	0.2	0.2	0.7	0.7	-0.8	0.1	0.1	0.4	-0.7	-0.2	0.3	-0.1	0.2	0.5	0.6
Pain all over the body in last month	0.2	0.2	0.6	-0.1	-0.6	-0.0	0.1	0.7	-0.5	-0.6	-0.6	0.3	0.1	0.4	0.2
Diabetes (self-reported)	0.2	0.3	2.9	-0.3	0.1	0.5	-0.3	-0.5	-0.4	-0.1	0.2	-1.7	0.2	-0.3	0.0
Weight	0.2	1.1	8.5	-1.5	0.3	0.4	0.2	2.9	-0.5	0.0	0.5	0.3	0.2	0.9	1.0
Arm fat percentage (right)	0.2	0.9	4.8	-1.2	-0.2	-0.8	-0.7	2.2	-1.2	-1.1	-0.3	-0.7	-0.3	-0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.5	4.1	0.8	2.0	-0.4	-0.2	-0.5	0.0	-1.1	-0.4	-0.4	0.0	-0.2	-0.1
Asthma	0.2	0.3	1.3	-1.1	0.9	-0.4	-0.7	-0.7	-0.3	-0.3	0.0	-0.4	-0.2	-0.5	-0.3
Prospective memory result	0.2	0.3	0.8	0.2	-0.1	0.7	0.7	0.3	0.7	-0.5	0.3	0.7	0.4	0.9	0.3
Breastfed as a baby	0.2	0.2	0.9	0.2	0.3	-0.2	0.1	-0.3	-0.1	0.7	-0.0	0.9	0.3	0.9	0.0
Pulse wave reflection index	0.2	0.2	0.7	-0.5	-0.1	-0.7	-0.6	-0.0	-0.0	-0.3	-0.6	-0.5	-0.2	-0.8	-0.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.0	-0.4	-0.8	0.0	-0.3	1.0	0.2	-0.1	-0.1	0.6	-0.8	-0.0	0.0
Headache pain in last month	0.2	0.4	1.8	0.8	-0.3	-0.2	0.3	1.3	0.5	0.4	0.3	0.9	0.1	0.7	0.8
Body fat percentage	0.2	0.6	5.1	-1.1	-0.8	-0.2	-0.5	2.3	-0.3	-0.4	0.1	0.1	-0.0	0.2	0.3
Arm fat-free mass (right)	0.2	0.9	3.6	-1.6	0.9	0.7	0.6	1.9	-0.1	0.4	0.9	0.5	0.2	0.9	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.1	1.1	0.2	-0.1	-0.2	-0.4	0.2	0.0	0.2	-0.6	0.6	-0.2	0.5
Qualifications: College or University degree	0.2	0.8	5.3	-0.1	-0.5	-0.2	-0.6	1.2	-0.1	-2.3	-0.8	0.7	-0.1	-0.7	-0.0
Medication: Omeprazole	0.2	0.2	1.2	-0.9	0.3	0.1	-0.0	0.7	-0.1	1.1	-0.0	0.2	0.1	-0.3	-0.3
Leg fat mass (right)	0.2	0.9	3.9	-1.8	-0.4	-0.5	-0.8	2.0	-1.0	-1.1	-0.2	-0.6	-0.4	-0.3	-0.1
Arm predicted mass (right)	0.2	1.0	3.8	-1.4	1.0	1.1	0.8	2.0	-0.0	0.3	1.1	0.4	0.4	1.0	1.1
Arm fat percentage (left)	0.2	1.0	5.4	-1.4	-0.3	-0.7	-0.8	2.3	-1.2	-0.8	-0.3	-0.8	-0.3	-0.3	-0.1
Eye problems/disorders: Cataract	0.2	0.2	1.0	-0.2	-0.3	1.0	0.9	0.0	-0.1	-0.1	0.4	-0.1	-0.1	0.7	0.4
Asthma (self-reported)	0.2	0.4	1.4	-1.2	1.1	-0.6	-0.8	-0.6	-0.4	-0.4	-0.1	-0.5	-0.2	-0.6	-0.4
Arm fat mass (left)	0.2	1.0	8.0	-1.3	0.2	-0.1	-0.1	2.8	-0.8	-0.6	0.2	-0.3	0.0	0.4	0.6
Number of self-reported non-cancer illnesses	0.2	0.3	1.9	-0.2	0.3	-0.2	-0.4	0.5	-0.8	0.6	0.2	-1.4	-0.3	-0.1	0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.8	0.0	0.1	0.6	0.1	-0.9	-0.1	1.4	0.3	-0.2	-0.1	0.2	0.4
High cholesterol (Self-reported)	0.2	0.4	1.7	-1.3	-0.9	-0.2	-0.4	0.7	-0.1	-0.0	0.1	-0.1	-0.4	-0.5	-0.8
Arm fat-free mass (left)	0.2	0.9	4.6	-1.3	1.1	0.8	0.6	2.1	-0.1	-0.1	0.9	0.4	0.2	1.0	1.1
Number of operations (self-reported)	0.2	0.3	1.4	-0.6	-1.2	-0.3	-0.1	0.3	0.4	-0.2	0.1	-0.3	1.0	0.1	0.7
Arm predicted mass (left)	0.2	0.8	3.5	-1.5	0.9	0.4	0.4	1.9	-0.3	-0.2	0.7	0.2	0.2	0.9	1.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	-0.3	-0.6	-0.3	-0.5	0.4	-0.6	-0.1	-0.2	-0.5	0.0	-0.6	-0.1
Neuroticism (2016)	0.1	0.1	0.8	0.5	-0.2	-0.4	-0.3	-0.2	-0.1	-0.9	0.2	-0.1	-0.0	-0.5	-0.1
Blood Platelet Count	0.1	1.5	5.0	0.3	2.2	1.0	1.2	1.4	0.8	-0.6	1.3	0.5	1.7	1.1	1.4
Systolic Blood Pressure	0.1	0.6	2.5	1.1	0.7	-0.5	0.2	0.5	0.4	0.4	0.0	0.8	-1.6	-0.2	-1.4
Respiratory disease	0.1	0.3	1.8	-1.3	-0.5	-0.1	-0.6	-1.0	0.1	-0.5	0.2	-0.4	-0.2	-0.3	-0.2
Hair Pigment	0.1	2.3	6.7	-2.6	1.6	-1.2	-1.2	-1.0	-2.3	0.5	-1.4	-1.6	-1.1	-1.3	-1.0
Average weekly fortified wine intake	0.1	0.1	0.6	-0.2	0.0	0.4	-0.1	0.5	-0.0	-0.1	0.0	-0.8	0.1	0.1	-0.1
Relative age voice broke	0.1	0.2	1.1	-1.0	-0.0	-0.3	-0.2	-0.5	-0.4	0.5	-0.2	-0.7	-0.4	0.0	-0.0
Taking other prescription medications	0.1	0.2	0.9	0.1	-0.2	0.1	-0.3	0.7	-0.2	-1.0	-0.1	-0.9	-0.1	-0.2	0.1
Multivitamins +/- minerals	0.1	0.1	0.5	0.2	-0.3	0.4	-0.2	-0.4	-0.4	0.3	-0.2	0.3	0.4	0.3	0.7
Qualifications: None of the above	0.1	0.3	1.7	0.8	1.0	-0.1	0.1	-1.3	-0.3	0.4	0.0	0.0	-0.2	0.3	-0.1
Hip circumference	0.1	0.6	4.7	-1.2	0.1	-0.4	0.1	2.2	-0.4	-0.0	0.4	0.1	0.2	0.6	0.7
Exposure to tobacco smoke at home	0.1	0.1	0.3	0.4	-0.1	0.2	-0.2	-0.4	-0.2	0.2	0.1	-0.3	-0.5	-0.2	0.1
Tense / ‘highly strung’	0.1	0.2	0.9	0.1	-0.8	-0.4	-0.2	-0.3	-0.2	-1.0	0.1	-0.3	-0.2	0.3	0.0
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.7	-0.1	0.1	0.2	0.2	-0.2	-0.1	0.7	-0.0	-0.9	0.4	0.1	0.1
Shortness of breath walking on level ground	0.1	0.1	0.5	0.4	0.1	-0.3	-0.1	0.0	0.0	-0.6	0.2	0.1	0.5	0.7	0.6
Pulse rate, automated reading	0.1	0.3	0.9	-0.9	-0.3	-0.4	-0.3	0.4	-0.4	-0.8	-0.3	-0.6	0.2	-0.5	-0.4
Breast cancer (self-reported)	0.1	0.1	0.6	0.8	0.3	-0.2	-0.4	0.2	-0.4	0.2	-0.2	-0.5	-0.2	0.0	0.2
Medication: Lisinopril	0.1	0.1	0.7	-0.3	-0.3	0.5	0.1	0.3	-0.2	-0.2	-0.1	-0.8	-0.4	-0.2	-0.4
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.2	0.5	0.4	0.1	-0.1	0.0	0.3	0.2	-0.3	-0.0	0.6	0.2
Tanning	0.0	0.4	1.8	-1.3	-0.1	0.1	-0.4	-0.4	0.2	-0.2	-0.4	-0.1	-1.0	-0.7	-0.8
Medication: Blood pressure	0.0	0.1	0.3	0.0	0.2	0.1	0.0	0.0	0.1	-0.0	0.2	-0.6	-0.2	-0.3	-0.5

Hub : Genes

CHPF2

Models

Trait associations