TWAS hub - CHRNA9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0421	0.0245	0.0086	0.010	0.006	0.006	NA	0.003	0.024	0.0600	0.066	NA	0.14
2	TCGA	Thyroid Carcinoma	0.0690	0.0320	0.0022	-0.003	0.017	0.007	NA	-0.002	0.890	0.0086	0.065	NA	0.53

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hypothyroidism (self reported)	7.4	17.1	32.1	-5.7	-1.4
Hypothyroidism/myxoedema (self-reported)	7.1	13.9	24.7	-5.0	-1.7
Medication: Levothyroxine sodium	5.5	9.3	15.9	-4.0	-1.6
Serious illness, injury or assault of a close relative in last 2 years	4.8	5.5	6.5	2.5	2.1
Length of working week for main job	4.2	4.6	5.6	2.4	1.9
Number of children fathered	4.1	4.6	5.3	-2.0	-2.3
Rheumatoid Arthritis	3.5	4.8	4.9	2.1	2.2
Financial difficulties in last 2 years	3.4	4.5	7.7	-2.8	-1.1
Falls in the last year	3.4	4.6	6.9	2.6	1.5
Bipolar Disorder (2011)	3.2	3.1	3.9	1.5	2.0
Number of operations (self-reported)	3.1	4.6	5.9	2.4	1.9
Chronic bronchitis/emphysema (father)	2.4	2.8	3.9	-1.3	-2.0
Alzheimer’s Disease (in father)	2.2	2.4	3.1	-1.3	-1.8
Mean time to correctly identify matches	2.2	4.1	7.3	1.0	2.7
Hand grip strength (right)	2.1	5.8	6.0	-2.5	-2.3
Family relationship satisfaction	1.9	2.3	2.5	-1.5	-1.6
Irritability	1.9	3.2	5.6	0.9	2.4
Medication: Paracetamol	1.8	3.0	4.9	1.1	2.2
Medication for pain relief, constipation, heartburn	1.8	3.1	3.4	-1.7	-1.9
Crohns Disease (2012)	1.7	2.7	4.5	-2.1	-0.9
Mood swings	1.7	3.0	5.9	-0.4	2.4
Medication: Paracetamol	1.7	2.6	2.9	1.5	1.7
Reaction Time	1.6	3.1	4.7	1.2	2.2
Alcohol intake versus 10 years previously	1.6	2.5	3.8	2.0	1.0
Lung cancer (father)	1.6	1.9	3.1	0.8	1.8
Pulse wave reflection index	1.6	2.0	2.5	1.6	-1.2
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	2.1	-1.5	-1.4
Primary Biliary Cirrhosis	1.5	2.2	4.3	2.1	-0.3
Ever had hysterectomy (womb removed)	1.5	1.6	3.3	1.8	0.1
Alcohol usually taken with meals	1.5	2.5	4.8	-0.4	-2.2
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	3.8	0.4	1.9
Number of full brothers	1.5	1.9	2.8	-1.0	-1.7
Illnesses of father: None of the above (group 1)	1.5	1.8	2.1	-1.4	1.3
Medication for hormone replacement therapy	1.4	1.5	2.5	1.6	-0.8
Medication: Ramipril	1.4	1.8	3.3	-1.8	-0.4
Pulse wave Arterial Stiffness index	1.4	1.6	3.2	1.8	-0.2
Exposure to tobacco smoke at home	1.4	1.6	3.1	0.4	1.7
Pulse wave peak to peak time	1.4	1.6	3.2	-1.8	0.1
Medication: Ibuprofen	1.4	1.7	2.1	1.4	1.2
Alcohol drinker status: Never	1.4	1.7	3.1	-0.5	1.8
Mean Putamen Volume	1.3	1.5	3.0	1.7	0.1
Allergy or Eczema	1.3	3.4	4.2	1.6	2.0
Serious illness, injury or assault to yourself	1.3	1.5	2.1	1.0	1.5
Hayfever, allergic rhinitis or eczema	1.3	2.8	3.6	1.4	1.9
Depression (self-reported)	1.3	1.6	1.7	-1.3	-1.2
Medication: Lansoprazole	1.3	1.4	2.8	-0.4	1.7
Glaucoma (self-reported)	1.3	1.5	3.0	0.1	-1.7
Alcohol intake frequency.	1.3	2.9	3.7	1.9	1.5
Leg pain on walking	1.3	1.7	2.9	1.7	0.7
Medication: Aspirin	1.3	1.7	2.4	1.6	1.0
Commuting to job workplace: Walk	1.3	1.4	1.9	1.4	0.9
Medication: Bendroflumethiazide	1.3	2.0	2.2	1.5	1.3
Pack years of smoking	1.3	1.8	3.4	0.6	1.8
Ovarian Cancer	1.2	1.5	3.1	-1.8	0.1
Fasting Glucose	1.2	1.5	3.0	-0.2	-1.7
Hand grip strength (left)	1.2	3.1	4.0	-2.0	-1.5
Emphysema/chronic bronchitis	1.2	1.4	1.6	1.2	-1.1
Knee pain experienced in last month	1.2	1.9	3.7	1.9	0.2
Long-standing illness, disability or infirmity	1.2	1.8	2.1	1.4	1.3
Medication: Aspirin	1.2	1.5	2.7	1.6	0.6
Number of self-reported non-cancer illnesses	1.2	2.1	3.4	0.9	1.9
Type 2 Diabetes (T2D) (2018)	1.1	2.0	3.0	1.7	1.0
Pack years adult smoking proportion	1.1	1.7	3.2	0.4	1.8
Worrier / anxious feelings	1.1	2.0	3.6	-1.9	0.7
Pulse rate	1.1	1.9	3.0	0.8	1.7
Overall health rating	1.1	2.4	2.5	1.6	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	2.4	-0.6	-1.5
Osteoarthritis (self-reported)	1.1	1.4	2.6	1.6	0.5
Medication: Gliclazide	1.1	1.3	1.8	0.9	-1.3
Depressed Affect (Nagel 2018)	1.0	2.1	4.0	-0.5	2.0
Alzheimer’s Disease (including proxy)	1.0	1.4	2.6	0.5	-1.6
Verbal and Numeric Reasoning (VNR)	1.0	2.4	4.6	2.2	0.5
Sensitivity / hurt feelings	1.0	1.7	2.7	0.9	1.6
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	1.5	1.0	1.2
Allergy	1.0	2.3	3.6	-1.0	-1.9
Number of live births	1.0	1.4	2.8	-0.0	1.7
Illnesses of mother	1.0	1.2	2.2	1.5	0.5
Birth weight of first child	1.0	1.9	3.6	-1.9	-0.3
Mineral and other dietary supplements	1.0	1.4	2.4	1.6	-0.6
Eye problems/disorders: Glaucoma	1.0	1.2	2.4	-0.0	-1.6
Bipolar Disorder (2018)	0.9	1.5	2.6	1.6	0.6
Chronotype (morning person)	0.9	2.0	2.6	-1.6	-1.2
Neuroticism score	0.9	1.9	3.6	-0.6	1.9
Happiness	0.9	1.1	2.2	0.2	-1.5
Hair/balding pattern: Pattern 4	0.9	2.2	4.4	-0.3	-2.1
Shortness of breath walking on level ground	0.9	1.1	1.8	1.3	0.7
Supplements: Calcium	0.9	1.0	1.6	0.7	1.3
Alcohol drinker status: Previous	0.9	1.1	2.1	1.5	0.1
Intelligence (Savage-Jansen 2018)	0.8	2.4	4.4	2.1	0.6
Worry (Nagel 2018)	0.8	1.7	3.2	-1.8	-0.3
Crohns Disease (2017)	0.8	1.7	2.9	-0.6	-1.7
Diabetes (father)	0.8	1.0	1.9	0.4	-1.4
Diabetes (mother)	0.8	1.0	1.4	0.8	1.2
Maternal smoking around birth	0.8	1.2	2.3	-0.3	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	1.9	-1.4	-0.7
Miserableness	0.8	1.3	2.4	-0.5	1.6
Commuting to job workplace: Public transport	0.8	0.9	1.4	0.6	-1.2
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.0	1.4	0.1
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.9	-1.4	0.4
Average weekly beer plus cider intake	0.8	1.1	1.5	1.2	0.9
Fractured/broken bones in last 5 years	0.8	1.0	1.4	1.2	-0.7
Prostate Cancer	0.7	1.0	2.1	-0.0	1.4
Cardiovascular Disease	0.7	2.2	3.5	1.9	1.0
Number of treatments/medications taken	0.7	1.3	2.3	0.5	1.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.3	0.7	-1.2
Nervous feelings	0.7	1.3	2.3	-1.5	-0.6
Had menopause	0.7	0.9	1.3	0.7	-1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.7	1.3	-0.1
Hair/balding pattern: Pattern 3	0.7	1.0	1.6	-0.7	-1.3
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.3	1.5	-0.9
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.6	-1.3	-0.2
Eye problems/disorders: None of the above	0.7	0.8	1.2	-0.7	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.4	-1.2	-0.5
Number of full sisters	0.7	0.8	1.2	0.7	1.1
Eye problems/disorders: Cataract	0.7	0.8	1.1	0.6	-1.1
Smoking status: Current	0.7	1.1	1.3	-1.1	-1.0
Medication: Atorvastatin	0.7	0.9	1.4	-1.2	0.6
Illnesses of father: High blood pressure	0.7	0.9	1.7	1.3	0.4
Pain experienced in last month	0.7	1.1	2.2	0.3	-1.5
Waist Hip Ratio (WHR)	0.6	2.7	3.3	-1.8	-1.5
Neuroticism	0.6	1.4	2.8	-0.2	1.7
Hearing difficulty/problems: Yes	0.6	1.0	1.9	1.4	-0.2
Medication: Co-codamol	0.6	0.7	1.2	1.1	0.4
Medication: Metformin	0.6	0.9	0.9	0.9	1.0
Severe depression (siblings)	0.6	0.6	0.9	0.9	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.4	-0.3	-1.2
Number of incorrect matches in round	0.6	1.0	1.4	-0.7	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.1	-0.8	-1.0
Illnesses of siblings	0.6	0.8	0.9	-0.8	0.9
Time employed in main current job	0.6	0.7	1.2	-0.3	-1.1
Medication: Cholesterol lowering	0.6	0.9	1.8	-0.3	1.3
Gout (self-reported)	0.6	0.9	1.4	0.6	1.2
High blood pressure (siblings)	0.6	0.9	1.3	-0.7	-1.1
Worry too long after embarrassment	0.6	1.0	1.6	-0.7	1.3
Medication: Seretide 50 evohaler	0.6	0.7	1.2	-1.1	0.4
Heart disease (mother)	0.6	0.7	1.2	-1.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	1.3	-1.2	-1.1
Loneliness, isolation	0.6	0.8	1.3	-1.1	0.6
Ever smoked	0.6	1.0	1.8	-0.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	0.9	0.8	1.0
Major Depression (MDD)	0.5	0.6	0.7	-0.8	-0.8
Age at First Birth	0.5	0.7	0.9	-0.7	-1.0
Coronary Artery Disease (CAD)	0.5	0.6	1.1	-1.1	-0.0
Schizophrenia (2014)	0.5	1.1	1.3	0.9	-1.1
Triglycerides	0.5	0.7	1.5	-1.2	0.1
Smoking Status	0.5	1.2	1.9	-0.7	-1.4
Fed-up feelings	0.5	0.9	1.0	-1.0	0.9
Age when periods started (menarche)	0.5	1.2	1.7	0.8	-1.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.8	0.6	-0.9
Stomach or abdominal pain in last month	0.5	0.6	0.9	-0.9	0.6
Pain all over the body in last month	0.5	0.5	1.0	1.0	-0.1
Medication: Simvastatin	0.5	0.7	0.8	0.8	0.9
Fluid intelligence score	0.5	1.1	2.3	1.5	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	0.8	0.7	0.9
Prospective memory result	0.5	0.6	0.7	-0.8	0.8
Headache pain in last month	0.5	0.8	0.8	-0.9	0.9
Birth weight	0.5	1.1	1.2	-1.0	-1.1
Neck or shoulder pain in last month	0.5	0.7	1.4	-1.2	-0.2
Illnesses of father: Heart disease	0.5	0.7	1.3	0.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	0.9	-0.9	0.3
Medication for cholesterol	0.5	0.8	1.4	-1.2	0.5
Hearing aid user	0.5	0.6	1.1	1.1	0.1
Bipolar Disorder or Schizophrenia	0.4	0.9	1.6	1.3	-0.3
Neuroticism (Nagel 2018)	0.4	1.0	1.3	-0.8	1.1
Relative age of first facial hair	0.4	0.7	1.0	-0.7	1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	0.7	-0.9	-0.5
Hearing difficulty/problems with background noise	0.4	0.6	1.2	1.1	0.2
Noisy workplace	0.4	0.5	0.8	-0.9	0.5
Breastfed as a baby	0.4	0.4	0.8	-0.3	-0.9
Wheeze or whistling in the chest in last year	0.4	0.8	1.4	1.2	0.4
Angina (self-reported)	0.4	0.5	0.8	0.4	0.9
Pulse rate, automated reading	0.4	1.4	2.3	0.8	1.5
Average weekly red wine intake	0.4	0.6	1.1	0.4	-1.0
Friendships satisfaction	0.4	0.5	0.9	1.0	0.3
Osteoporosis (self-reported)	0.4	0.5	0.8	0.5	0.9
Mother’s age at death	0.4	0.6	0.9	-0.4	-1.0
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.9	-0.4	-0.9
Medication: Lisinopril	0.4	0.5	0.9	0.4	0.9
Depression (Nagel 2018)	0.3	0.5	1.0	-1.0	-0.1
LDL Cholesterol	0.3	0.4	0.8	0.0	-0.9
Respiratory disease	0.3	0.7	0.7	0.8	0.8
Lung FVC	0.3	1.7	3.4	0.1	-1.8
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.8	-0.3	0.9
Systolic blood pressure, automated reading	0.3	1.0	1.7	1.3	-0.5
Current tobacco smoking	0.3	0.5	0.6	-0.8	-0.7
Relative age voice broke	0.3	0.5	0.6	0.7	0.8
Multivitamins +/- minerals	0.3	0.4	0.5	0.7	0.6
Supplements: Glucosamine	0.3	0.4	0.9	-0.9	-0.1
Past tobacco smoking	0.3	0.6	1.2	0.2	1.1
Forced vital capacity (FVC)	0.3	1.1	2.2	-0.3	-1.5
Mouth/teeth dental problems: Dentures	0.3	0.5	0.9	0.5	0.9
Tense / ‘highly strung’	0.3	0.5	0.7	-0.5	-0.9
Peak expiratory flow (PEF)	0.3	0.7	0.9	0.7	0.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.7	0.5	0.9
Blood clot in the leg (DVT)	0.3	0.4	0.6	0.6	0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	0.5	-0.7	-0.6
Exposure to tobacco smoke outside home	0.3	0.4	0.5	-0.7	0.6
Comparative body size at age 10	0.3	0.8	1.1	-0.7	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.7	-0.8	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	-0.1	-0.8
Medication: Allopurinol	0.3	0.4	0.7	-0.4	0.8
Medication: Omeprazole	0.3	0.4	0.5	0.4	-0.7
Comparative height size at age 10	0.3	1.6	2.7	-1.6	-0.8
Had major operations	0.3	0.3	0.4	0.5	0.6
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.6	-0.2	0.8
Diabetes diagnosed by doctor	0.3	0.5	1.1	1.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.6	-0.8	-0.3
Back pain experienced in last month	0.3	0.4	0.8	-0.1	0.9
High cholesterol (Self-reported)	0.3	0.6	1.0	0.4	1.0
Risk taking	0.3	0.4	0.7	0.3	0.9
Basal cell carcinoma (self-reported)	0.3	0.3	0.4	-0.7	0.5
Schizophrenia (2018)	0.2	0.4	0.5	0.5	-0.7
Alzheimer’s Disease (in mother)	0.2	0.3	0.5	0.7	-0.1
Irritable Bowel Disease (IBD)	0.2	0.5	0.6	-0.6	-0.8
Breast Cancer	0.2	0.4	0.6	0.5	-0.8
Neuroticism (2016)	0.2	0.2	0.4	-0.6	0.3
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.1	0.6
Vitamin and mineral supplements	0.2	0.3	0.4	-0.4	-0.6
Taking other prescription medications	0.2	0.3	0.6	0.8	0.3
Qualifications: CSEs or equivalent	0.2	0.3	0.5	-0.7	-0.2
High blood pressure	0.2	0.4	0.7	0.4	0.8
Had other major operations	0.2	0.2	0.4	0.6	0.0
Diabetes (self-reported)	0.2	0.3	0.6	0.8	-0.1
Standing height	0.2	1.6	1.9	-1.4	-1.1
Forced vital capacity (FVC), Best measure	0.2	0.8	1.5	-0.2	-1.2
Age at first live birth	0.2	0.3	0.4	-0.5	-0.6
Health satisfaction	0.2	0.2	0.3	0.4	-0.6
Qualifications: College or University degree	0.2	0.7	1.3	-0.2	-1.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	-0.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.4	0.6	0.4
Smoking status: Previous	0.2	0.3	0.7	0.0	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.2	0.2	0.5	-0.1	-0.7
Average weekly champagne plus white wine intake	0.2	0.3	0.4	0.4	-0.7
Guilty feelings	0.2	0.2	0.3	0.5	0.5
Financial situation satisfaction	0.2	0.3	0.5	-0.3	-0.7
Medication: Blood pressure	0.2	0.3	0.5	0.3	0.7
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.5	0.2	0.7
Age started oral contraceptive pill	0.2	0.3	0.5	-0.7	-0.1
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.1	-0.4	-1.1
Schizophrenia vs Biploar Disorder	0.1	0.2	0.3	-0.5	-0.3
Ulcerative Colitis (UC)	0.1	0.1	0.2	-0.2	0.4
Body Mass Index (BMI) (2010)	0.1	0.2	0.3	-0.1	-0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	0.5	0.1
Ulcerative Colitis	0.1	0.2	0.4	-0.6	0.2
Blood Platelet Count	0.1	0.9	0.9	-0.9	0.9
Blood Red Count	0.1	0.8	1.1	-1.1	-0.7
Heel T-Score	0.1	1.1	1.7	0.8	1.3
BMI	0.1	0.3	0.5	0.4	0.7
Systolic Blood Pressure	0.1	0.7	1.4	1.2	-0.2
Lung FEV1/FVC ratio	0.1	0.3	0.4	0.4	0.6
Average weekly spirits intake	0.1	0.1	0.2	-0.3	0.4
Angina	0.1	0.2	0.2	0.4	0.5
Supplements: Zinc	0.1	0.1	0.3	0.1	-0.5
Impedance of leg (right)	0.1	0.5	0.9	-1.0	0.3
Trunk fat percentage	0.1	0.6	1.0	-1.0	0.4
Townsend deprivation index at recruitment	0.1	0.2	0.4	0.2	0.6
Average weekly fortified wine intake	0.1	0.1	0.2	-0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.3	-0.5	-0.3
Impedance of leg (left)	0.1	0.5	0.8	-0.9	0.4
Trunk fat mass	0.1	0.5	0.9	-0.9	0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	0.4	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.4	-0.6	-0.3
Qualifications: None of the above	0.1	0.1	0.2	0.3	0.4
Heart attack	0.1	0.2	0.3	-0.5	-0.2
Weight	0.1	0.3	0.4	-0.7	-0.4
Arm fat percentage (right)	0.1	0.2	0.4	-0.6	0.1
Trunk fat-free mass	0.1	0.4	0.4	-0.6	-0.6
Hip circumference	0.1	0.3	0.5	-0.7	0.5
Father’s age at death	0.1	0.1	0.1	-0.3	0.3
Asthma	0.1	0.1	0.2	-0.5	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	0.2	-0.6
Impedance of arm (left)	0.1	0.4	0.6	-0.8	-0.4
Arm fat mass (right)	0.1	0.4	0.7	-0.8	0.1
Trunk predicted mass	0.1	0.4	0.4	-0.6	-0.6
Loud music exposure frequency	0.1	0.1	0.1	0.1	0.3
Body fat percentage	0.1	0.5	1.0	-1.0	-0.1
Leg fat percentage (right)	0.1	0.3	0.6	-0.7	-0.2
Migraine (self-reported)	0.1	0.1	0.3	-0.1	-0.5
Whole body fat mass	0.1	0.5	1.0	-1.0	-0.0
Suffer from ‘nerves’	0.1	0.2	0.3	-0.4	0.5
Age at last live birth	0.1	0.1	0.1	-0.3	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.4	0.1
Supplements: Vitamin C	0.1	0.1	0.1	0.2	0.3
Hypertension (Self-reported)	0.1	0.2	0.4	0.0	0.6
Illnesses of siblings: Diabetes	0.1	0.2	0.3	0.6	-0.2
Arm fat percentage (left)	0.1	0.2	0.4	-0.6	-0.1
Ever had bowel cancer screening	0.1	0.2	0.3	0.2	0.5
Qualifications: nursing, teaching	0.1	0.1	0.3	0.0	-0.5
Asthma (self-reported)	0.1	0.1	0.2	-0.2	0.4
Arm fat mass (left)	0.1	0.3	0.6	-0.7	0.0
Wears glasses or contact lenses	0.1	0.1	0.3	0.5	0.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.1	0.5
Arm fat-free mass (left)	0.1	0.3	0.7	-0.8	-0.0
Diastolic blood pressure, automated reading	0.1	0.4	0.7	-0.3	-0.9
Ever depressed for a whole week	0.1	0.1	0.2	0.2	-0.5
Myopia	0.1	0.1	0.2	0.2	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	0.3	-0.3
Heart disease (siblings)	0.1	0.2	0.2	0.3	-0.5
Impedance of whole body	0.1	0.4	0.8	-0.9	-0.0
HbA1C	0.0	0.0	0.0	0.2	0.1
HDL Cholesterol	0.0	0.0	0.0	0.0	0.2
Lupus	0.0	0.0	0.0	0.1	0.2
Blood Eosinophil Count	0.0	0.2	0.4	0.2	-0.7
Blood White Count	0.0	0.3	0.5	0.2	0.7
Height	0.0	0.5	0.7	-0.9	-0.6
Hair Pigment	0.0	1.0	1.8	-0.3	-1.4
Tanning	0.0	0.4	0.6	-0.4	0.8
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.0	0.2
Leg fat-free mass (left)	0.0	0.0	0.0	-0.1	0.1
Medication: Atenolol	0.0	0.0	0.0	0.1	0.2
Sitting height	0.0	0.2	0.2	-0.5	-0.3
High blood pressure (mother)	0.0	0.0	0.1	-0.1	-0.3
Body mass index (BMI)	0.0	0.0	0.0	-0.1	0.2
Leg predicted mass (left)	0.0	0.0	0.0	-0.1	0.1
Waist circumference	0.0	0.0	0.1	-0.3	0.0
Mouth/teeth dental problems	0.0	0.1	0.1	0.3	-0.2
Impedance of arm (right)	0.0	0.1	0.2	-0.1	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.2	0.1	-0.5
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.0	0.0	-0.1
Medication: Amlodipine	0.0	0.0	0.0	0.1	0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	-0.1	0.2
Arm fat-free mass (right)	0.0	0.2	0.2	-0.4	-0.4
Medication: Blood pressure	0.0	0.0	0.0	0.2	0.2
Leg fat mass (right)	0.0	0.1	0.3	-0.5	-0.1
Arm predicted mass (right)	0.0	0.1	0.3	-0.5	-0.1
Chest pain or discomfort	0.0	0.0	0.1	-0.3	-0.1
Whole body fat-free mass	0.0	0.1	0.2	-0.5	-0.2
Leg fat-free mass (right)	0.0	0.0	0.0	0.1	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.1	0.1	0.2	0.3
Breast cancer (self-reported)	0.0	0.0	0.0	-0.2	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	0.2	-0.2
Whole body water mass	0.0	0.1	0.2	-0.4	-0.2
Leg predicted mass (right)	0.0	0.0	0.0	-0.0	0.1
Basal metabolic rate	0.0	0.2	0.3	-0.6	-0.2
Leg fat percentage (left)	0.0	0.1	0.2	-0.5	-0.1
Unable to work because of sickness or disability	0.0	0.0	0.1	0.0	-0.2
Commuting to job workplace: Cycle	0.0	0.0	0.1	0.3	0.2
Cholesterol lowering medication	0.0	0.1	0.1	0.2	0.3
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	-0.2	0.2
Leg fat mass (left)	0.0	0.1	0.1	-0.3	0.0
Arm predicted mass (left)	0.0	0.1	0.1	-0.4	0.0

Hub : Genes

CHRNA9

Models

Trait associations