Hub : Genes

CIAPIN1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0860	0.0290	6.5e-04	0.003	0.021	0.001	0.015	0.006	1.4e-01	1.3e-03	2.2e-01	0.0057	6.1e-02
2	GTEx	Cells Transformed fibroblasts	0.2620	0.0510	2.0e-07	0.152	NA	0.183	NA	0.179	1.7e-11	NA	1.1e-13	NA	1.9e-13
3	GTEx	Esophagus Mucosa	0.2080	0.0540	1.4e-04	0.133	NA	0.156	NA	0.148	3.5e-09	NA	1.3e-10	NA	4.2e-10
4	GTEx	Skin Sun Exposed Lower leg	0.1510	0.0510	2.2e-03	0.133	NA	0.116	NA	0.130	4.2e-11	NA	7.7e-10	NA	6.7e-11
5	GTEx	Testis	0.4760	0.0690	6.7e-12	0.320	NA	0.383	NA	0.377	9.0e-15	NA	4.5e-18	NA	9.0e-18
6	GTEx	Vagina	0.4780	0.1360	7.2e-03	-0.009	NA	0.007	NA	-0.006	5.6e-01	NA	2.1e-01	NA	4.6e-01
7	TCGA	Bladder Urothelial Carcinoma	0.0550	0.0280	2.2e-03	0.028	0.034	0.025	NA	0.029	1.9e-03	7.3e-04	3.0e-03	NA	1.7e-03
8	TCGA	Breast Invasive Carcinoma	0.0205	0.0100	6.0e-04	0.003	0.016	0.005	NA	0.006	5.4e-02	2.3e-04	3.1e-02	NA	1.9e-02
9	TCGA	Colon Adenocarcinoma	0.1340	0.0470	3.3e-07	0.103	0.127	0.126	NA	0.119	1.5e-06	9.2e-08	1.0e-07	NA	2.2e-07
10	TCGA	Glioblastoma Multiforme	0.3650	0.1210	6.7e-03	0.126	-0.005	0.041	NA	0.089	1.2e-04	4.8e-01	2.2e-02	NA	1.2e-03
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0834	0.0333	4.3e-07	0.038	0.055	0.045	NA	0.058	3.7e-05	7.6e-07	8.2e-06	NA	4.4e-07
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0635	0.0299	1.9e-04	0.025	0.026	0.011	NA	0.014	6.8e-04	5.3e-04	1.7e-02	NA	9.8e-03
13	TCGA	Lung Adenocarcinoma	0.0684	0.0347	5.1e-03	0.012	0.032	0.022	NA	0.016	1.4e-02	1.2e-04	1.2e-03	NA	5.1e-03
14	TCGA	Lung Squamous Cell Carcinoma	0.0497	0.0247	9.1e-04	0.008	0.016	0.001	NA	0.002	4.0e-02	5.2e-03	2.1e-01	NA	1.5e-01
15	TCGA	Stomach Adenocarcinoma	0.1170	0.0490	2.6e-04	0.053	0.065	0.043	NA	0.042	1.1e-04	1.9e-05	4.4e-04	NA	4.8e-04
16	TCGA	Thyroid Carcinoma	0.1260	0.0580	4.9e-04	0.012	0.035	0.047	NA	0.041	2.4e-02	2.1e-04	2.2e-05	NA	7.3e-05
17	TCGA	Uterine Corpus Endometrial Carcinoma	0.2340	0.1130	9.2e-03	0.067	0.044	0.004	NA	0.037	6.2e-03	2.3e-02	2.4e-01	NA	3.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.1	0.2	0.7	-0.2	0.1	0.7	0.3	0.5	0.0	0.6	0.1	-0.1	-0.1	-0.1	-0.3	0.8	0.7	0.6	-0.6	0.1
Bipolar Disorder or Schizophrenia	0.2	0.6	2.9	-1.0	-0.2	0.6	-0.1	1.7	0.0	-0.1	-0.8	-0.6	-0.4	-0.8	-1.0	0.2	0.2	0.9	-1.1	0.2
Depressed Affect (Nagel 2018)	0.4	0.8	4.1	1.0	-0.1	0.3	-0.4	-2.0	1.3	-0.6	0.6	0.1	-1.6	0.2	0.4	0.5	-0.2	-1.4	1.1	-0.5
Depression (Nagel 2018)	1.1	1.6	6.3	1.6	-0.6	-0.6	-1.6	-2.5	-0.2	-1.7	-0.7	-1.0	-1.5	-1.0	-0.4	0.2	-1.1	-1.9	1.1	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.6	3.5	-0.6	-0.8	-1.6	-1.5	0.3	1.9	-1.9	-1.8	-1.8	0.5	-1.1	-1.2	-0.7	-1.5	-0.9	-0.6	-1.4
Neuroticism (Nagel 2018)	0.4	0.9	4.7	1.4	0.6	-0.0	-0.5	-2.2	1.2	-0.4	0.8	0.5	-0.7	0.4	0.8	0.3	-0.1	-0.9	1.5	-0.5
Schizophrenia (2018)	0.3	0.6	3.1	-1.0	-0.4	0.1	-0.3	1.8	0.0	-0.6	-1.1	-0.7	-0.5	-1.0	-1.1	-0.4	-0.3	0.7	-1.0	0.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.9	-1.4	0.3	0.4	0.1	0.1	0.0	-0.9	-0.6	-0.4	0.5	-0.0	0.2	1.0	-0.1	0.7	0.5	0.5
Worry (Nagel 2018)	0.3	0.7	3.2	1.1	0.5	-0.3	-0.3	-1.8	0.8	0.2	0.9	0.6	-0.2	0.3	0.8	-0.2	0.0	-1.1	1.4	-0.8
Alzheimer’s Disease (in mother)	1.1	1.3	3.3	-0.1	-1.0	-1.4	-1.2	0.2	-0.4	-1.8	-1.4	-1.6	1.3	-0.6	-0.6	-1.0	-1.6	-1.3	-0.7	-1.3
Alzheimer’s Disease (in father)	1.5	1.6	7.8	-2.8	-0.9	-1.0	-0.6	1.9	-1.7	-0.6	-1.2	-0.8	0.2	-1.0	-1.4	-1.4	-1.3	0.1	-1.2	-0.9
Alzheimer’s Disease (including proxy)	1.1	1.6	2.6	-1.3	-1.2	-1.1	-0.8	1.6	-1.3	-1.6	-1.6	-1.5	1.4	-0.6	-0.9	-1.3	-1.6	-0.7	-1.0	-1.1
Crohns Disease (2017)	0.7	1.6	5.2	0.9	0.7	1.1	1.3	-1.2	-2.3	0.9	1.5	0.8	0.5	1.9	2.1	0.1	1.4	-0.9	1.5	0.6
Irritable Bowel Disease (IBD)	0.5	1.2	6.4	1.4	0.9	0.7	0.5	-1.6	-2.5	0.0	1.0	0.8	-0.6	1.3	1.4	0.4	0.7	-0.4	0.9	0.4
Ulcerative Colitis (UC)	0.4	0.7	4.2	1.2	0.8	-0.1	-0.6	-1.6	-2.1	-0.7	0.3	0.5	-1.3	0.3	0.3	0.3	-0.2	0.0	0.3	-0.1
Major Depression (MDD)	0.3	0.4	2.8	-0.1	-0.7	0.9	0.3	0.2	0.0	0.2	0.1	-0.3	-1.7	0.1	-0.1	0.8	0.3	-0.5	-0.7	0.3
Reaction Time	0.6	1.1	4.0	0.1	-0.2	1.6	2.0	0.6	1.0	0.5	0.6	0.9	1.0	1.2	0.2	1.4	0.4	1.3	0.1	1.7
Verbal and Numeric Reasoning (VNR)	1.4	3.2	7.2	-0.2	-1.0	-2.6	-2.4	-0.1	2.7	-2.5	-2.3	-2.2	0.9	-1.8	-1.6	-1.0	-2.0	-1.0	-1.0	-2.2
Breast Cancer	0.2	0.5	4.1	-0.3	-0.7	0.5	1.0	0.9	2.0	0.6	0.1	0.4	0.5	-0.0	-0.4	0.1	0.2	0.4	-0.6	0.6
Ovarian Cancer	1.2	1.6	4.8	-1.2	-1.7	-1.5	-0.9	-0.7	2.2	-0.9	-0.7	-0.6	0.2	-1.2	-1.4	-0.9	-1.3	-1.3	-1.5	-1.5
Prostate Cancer	1.3	1.8	7.1	-2.7	-1.4	-0.8	-1.1	0.6	0.4	-0.9	-1.1	-1.2	-0.8	-1.0	-1.4	-1.4	-1.2	-1.5	-2.2	-1.3
Age at First Birth	0.3	0.5	2.6	0.6	-0.5	-0.2	0.2	-0.2	0.0	-0.9	-0.8	-0.5	-0.3	-0.5	-1.1	1.6	-0.9	0.4	0.1	1.0
Bipolar Disorder (2011)	0.6	0.6	2.4	0.0	0.0	0.0	0.0	0.0	0.0	-0.5	-0.7	-0.5	-0.3	-0.9	-1.1	-1.2	-0.7	-0.5	-1.6	-1.3
Body Mass Index (BMI) (2010)	0.2	0.2	1.0	-0.1	0.5	0.4	-0.4	-0.9	0.0	-0.4	-0.0	-0.3	0.5	0.3	0.8	-0.1	0.2	-0.4	1.0	-0.4
Coronary Artery Disease (CAD)	0.7	0.8	2.6	1.1	0.6	1.5	1.2	-0.4	0.0	0.1	0.5	0.5	-0.4	0.9	0.7	1.6	0.8	1.1	0.4	1.3
Crohns Disease (2012)	0.7	1.1	3.1	1.1	0.4	1.5	1.8	-0.4	0.0	0.8	0.8	0.6	0.7	1.4	1.5	0.6	1.5	0.5	0.5	1.5
Mean Putamen Volume	0.4	0.5	2.0	-1.0	-0.2	0.9	0.7	1.0	0.0	-0.6	-0.5	-0.6	1.4	0.3	-0.0	1.1	0.1	0.5	-0.1	0.3
Fasting Glucose	0.7	0.8	2.6	1.4	1.1	1.4	0.5	-0.2	0.0	0.1	0.5	0.4	-0.3	0.8	1.1	1.6	1.0	1.1	0.4	1.0
HbA1C	0.2	0.2	1.0	0.4	-0.8	1.0	-0.1	0.6	0.0	-0.3	0.2	-0.1	-0.3	0.2	0.2	-0.2	-0.1	-0.6	-0.7	-0.4
HDL Cholesterol	1.3	2.2	27.5	5.2	0.1	-0.5	-0.8	0.8	0.0	-0.1	-0.8	-0.0	-1.2	-1.3	-1.1	0.3	-0.4	1.6	-0.9	0.3
LDL Cholesterol	2.6	4.2	13.7	-1.1	1.7	3.7	2.5	0.3	0.0	1.5	1.5	1.1	-0.7	2.5	2.1	3.4	2.7	2.1	0.1	2.6
Lupus	1.5	2.2	10.4	3.2	1.4	0.6	0.4	-3.0	0.1	-0.4	0.5	0.9	-0.3	0.9	1.1	2.2	0.8	1.7	1.0	1.7
Neuroticism (2016)	0.7	1.0	4.1	1.2	-0.3	-0.5	-0.8	-1.9	2.0	-1.4	-0.5	-0.4	-1.1	-0.5	-0.6	0.7	-0.8	-0.4	-0.7	-0.9
Primary Biliary Cirrhosis	0.6	0.8	6.5	2.5	0.2	0.7	0.0	-1.6	0.0	-0.5	-0.0	0.3	-1.2	-0.2	-0.3	1.5	-0.3	0.4	-0.1	0.3
Rheumatoid Arthritis	0.8	1.1	5.3	0.4	-0.7	2.3	1.6	0.6	0.0	0.9	0.7	0.6	-1.8	0.6	0.3	0.5	1.1	-0.1	-0.5	1.5
Schizophrenia (2014)	0.4	0.9	3.2	-1.3	-0.5	0.1	-0.4	1.8	0.0	-0.4	-1.1	-0.7	-0.7	-1.3	-1.4	-0.2	-0.2	0.8	-1.5	-0.2
Triglycerides	0.3	0.6	2.9	-1.7	0.1	1.3	1.0	0.6	0.0	0.4	0.5	0.5	0.2	0.9	0.6	0.2	0.6	0.4	0.1	1.0
Type 2 Diabetes (T2D) (2012)	0.8	0.9	4.9	1.1	1.0	-0.2	-1.0	-2.2	0.0	-1.2	-0.4	-0.3	-0.6	-0.0	0.3	1.4	-0.5	0.1	1.5	0.6
Ulcerative Colitis	0.4	0.6	3.0	1.5	0.8	0.3	-0.4	-1.7	0.0	-1.2	-0.2	-0.0	-0.1	0.4	0.4	1.1	-0.3	0.3	0.6	0.1
Blood Eosinophil Count	0.5	4.2	16.6	-0.7	0.2	-1.6	1.1	-0.5	0.2	3.5	3.2	3.4	2.7	0.8	1.0	-4.1	0.9	-1.2	2.0	-0.9
Blood Platelet Count	0.1	1.1	5.6	-2.4	0.3	0.4	0.7	-0.1	-0.7	0.0	0.5	1.3	-1.6	0.7	-0.5	0.2	-0.2	1.5	-2.2	0.2
Blood Red Count	0.1	1.4	7.6	-1.2	-0.4	-0.6	0.1	2.8	-0.7	1.1	-0.2	0.6	-0.4	-1.2	-1.2	-2.4	-0.1	1.0	-1.1	-0.9
Blood White Count	0.2	1.5	8.8	-3.0	-1.4	-1.5	-0.6	0.6	-0.6	-0.1	-0.2	0.2	-0.1	-1.1	-1.3	-2.2	-1.0	-0.9	-1.1	-1.2
Heel T-Score	0.2	1.7	6.1	-1.4	-0.6	-1.6	-1.3	2.5	-0.4	0.3	-1.0	-1.4	1.0	-1.6	-0.8	-2.2	-0.3	-1.2	0.2	-1.5
BMI	0.2	1.2	3.8	0.3	-1.5	-0.6	-0.6	-0.7	0.1	-1.9	-1.7	-1.3	1.4	-1.1	-1.2	0.1	-1.3	-0.3	-1.1	-0.1
Height	0.1	1.1	3.8	-1.6	0.8	1.4	0.2	1.8	0.5	0.0	0.1	0.0	-2.0	0.9	0.0	1.4	0.3	1.4	-0.5	0.9
Waist Hip Ratio (WHR)	0.5	2.1	4.7	0.8	1.4	1.7	1.7	-0.9	-0.4	1.3	1.8	1.6	-0.6	1.7	1.6	1.5	1.4	0.7	2.2	1.7
Systolic Blood Pressure	0.0	0.2	0.7	-0.7	0.7	-0.4	0.6	0.2	0.4	0.4	0.2	0.4	0.7	0.2	0.4	0.3	0.4	0.8	0.5	0.3
Smoking Status	0.7	1.8	5.0	-1.4	-2.2	-0.9	-0.8	-0.6	-0.8	-1.4	-1.3	-1.4	-0.8	-1.7	-1.8	-0.2	-1.7	-2.0	-0.5	-1.2
Allergy or Eczema	0.5	1.3	4.3	0.6	-0.9	-1.4	-1.2	-0.4	-2.1	-0.1	-0.8	-0.4	1.5	-1.9	-1.0	-1.7	-0.7	-0.5	-0.5	-1.3
Cardiovascular Disease	0.6	2.1	5.6	0.6	2.3	0.1	0.4	-2.4	1.2	0.9	1.3	1.9	0.4	1.2	1.7	0.8	1.4	2.1	1.1	1.9
Hypothyroidism (self reported)	0.4	0.9	5.9	2.4	0.4	-1.3	-0.7	0.0	0.8	0.5	0.3	0.6	-0.0	-0.2	-0.0	-2.1	-0.1	-0.2	-0.3	-0.8
Respiratory disease	0.7	1.5	6.0	-2.3	-1.2	-0.4	0.3	1.5	-1.3	1.1	-0.3	-0.3	2.4	-1.3	-0.5	-2.1	0.3	-0.8	0.1	-0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.5	2.0	-0.5	0.9	0.7	0.0	0.4	1.4	-0.2	0.3	0.2	0.0	1.1	0.7	0.4	0.2	0.5	1.0	0.7
Lung FEV1/FVC ratio	0.3	1.6	5.2	0.6	-0.2	-1.1	-1.9	-2.0	-0.6	-2.3	-1.2	-1.7	-0.1	-0.4	-0.4	0.6	-1.5	-1.5	-0.1	-1.5
Lung FVC	0.1	0.7	5.8	-0.7	-0.7	-0.0	0.0	2.4	1.2	0.0	-0.4	-0.8	0.4	-0.3	-0.5	-0.9	-0.4	-0.9	0.2	-0.3
Neuroticism	0.4	1.1	3.4	0.3	-0.8	-0.8	-1.2	-0.9	0.8	-1.4	-0.8	-1.2	-0.7	-0.9	-0.8	-0.5	-1.0	-1.7	-0.9	-1.8
Chronotype (morning person)	0.3	0.7	4.2	0.1	-0.9	0.9	-0.3	0.4	1.0	-0.3	-0.7	-0.8	-2.0	-0.8	-1.1	0.8	-0.2	-0.2	-1.3	-0.2
Hair Pigment	0.1	1.6	10.5	1.1	-0.4	-1.4	-1.3	-1.8	-3.2	-0.1	-0.0	0.1	-0.3	-1.4	-0.6	-1.3	-0.8	-1.2	1.1	-1.0
Tanning	0.2	1.9	5.7	1.6	1.6	1.5	1.6	0.1	0.4	0.8	1.1	1.7	-0.5	1.5	0.8	1.7	0.7	2.4	1.3	1.8
Hand grip strength (left)	0.3	0.8	3.6	-0.2	0.3	0.3	0.2	0.9	-1.9	0.1	-0.6	-0.3	1.7	-0.3	-0.3	0.8	0.4	1.6	-1.3	0.3
Number of treatments/medications taken	0.8	1.5	9.7	0.9	0.8	-0.0	0.3	-3.1	1.3	0.4	0.8	0.6	1.5	0.5	1.4	0.7	0.8	-0.4	2.1	0.6
Average weekly spirits intake	0.5	0.6	2.5	0.4	-1.6	-0.4	0.3	0.5	-0.3	-0.4	-0.8	-0.3	-0.1	-1.0	-1.5	-0.6	-0.9	-0.5	-0.9	-0.3
Sensitivity / hurt feelings	0.5	0.8	3.3	1.1	1.6	0.0	-0.1	-1.3	0.5	0.0	0.5	0.3	0.2	0.5	1.0	1.4	0.5	0.7	1.8	0.3
Frequency of depressed mood in last 2 weeks	1.4	1.9	11.0	1.5	-0.7	-0.9	-1.5	-3.3	-0.2	-1.8	-0.8	-1.2	-0.8	-0.7	-0.4	0.0	-1.0	-2.1	-1.3	-1.5
Hearing difficulty/problems: Yes	0.5	0.8	4.0	2.0	0.3	0.1	0.3	-2.0	1.4	0.5	0.6	0.7	0.7	0.6	0.8	0.1	0.6	0.1	-0.4	0.8
Relative age of first facial hair	0.2	0.5	1.7	-1.3	-0.2	0.8	0.4	1.1	-0.6	0.1	-0.4	-0.2	-0.7	-0.4	-0.6	1.1	-0.0	0.9	0.3	0.8
Other serious medical condition/disability diagnosed by doctor	1.4	1.9	8.5	1.3	1.3	1.0	1.3	-1.7	1.0	1.0	1.1	0.9	2.9	1.5	1.7	0.8	1.5	0.4	0.6	1.2
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.5	0.6	-0.0	-0.9	-1.1	-0.3	-0.3	-0.9	-0.8	-1.1	0.8	-0.6	0.1	-1.0	-0.5	-1.2	0.2	-1.2
Ever had hysterectomy (womb removed)	0.4	0.5	2.7	-0.5	-1.4	0.4	0.4	0.2	1.6	-0.2	-0.2	-0.3	0.3	-0.4	-0.7	-0.4	-0.3	-1.1	-0.9	-0.5
Systolic blood pressure, automated reading	0.4	1.2	2.5	0.4	1.3	1.0	1.4	-0.9	-0.5	1.1	1.4	1.4	0.3	1.6	1.6	1.1	1.2	1.0	0.8	1.0
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	3.6	1.1	0.6	1.6	1.4	-1.8	0.7	0.8	1.6	1.9	-1.8	1.2	0.8	1.4	1.0	1.0	0.3	1.6
Angina	1.4	1.8	5.5	1.1	0.8	1.1	1.2	-1.6	1.5	0.6	0.8	1.1	-0.1	0.9	1.1	2.2	1.0	1.4	2.0	2.4
Medication for hormone replacement therapy	0.6	0.6	2.7	0.6	-1.2	-0.7	0.2	0.1	0.9	-0.3	0.2	0.2	-0.1	-0.3	-0.6	-1.6	-1.0	-1.5	0.2	-0.9
Vitamin and mineral supplements	0.6	0.8	2.6	-1.0	0.8	0.4	0.3	0.1	-1.6	1.4	0.9	0.7	0.3	0.8	1.3	-0.5	1.3	0.3	-0.6	-0.1
Supplements: Zinc	0.3	0.3	2.3	-0.0	-0.1	0.2	0.6	1.5	1.0	0.5	0.0	0.4	0.6	-0.3	-0.5	0.0	0.1	0.9	0.3	0.2
Medication: Co-codamol	0.6	0.7	3.8	1.2	0.1	-0.6	0.1	-1.3	1.3	0.8	0.5	0.6	2.0	-0.1	0.5	-0.6	0.4	-0.3	0.7	-0.3
Medication: Metformin	1.3	1.8	4.7	1.9	1.5	1.3	0.5	-2.1	0.5	0.1	0.9	0.9	0.3	1.6	1.3	2.2	0.7	1.1	1.7	1.8
Diabetes (father)	0.3	0.4	1.9	-0.2	-1.0	0.1	0.6	0.6	0.7	0.3	-0.2	0.2	-0.2	-0.3	-1.1	0.4	-0.3	0.5	-1.4	0.4
Diabetes (mother)	0.2	0.2	2.0	0.5	0.7	0.2	-0.3	-0.5	-0.2	-0.3	0.2	0.2	-1.4	0.4	0.4	0.5	0.2	0.2	-0.1	-0.1
Severe depression (siblings)	0.7	0.8	1.7	0.3	0.4	1.0	0.9	-1.3	-0.9	0.7	1.2	0.9	-1.3	1.3	0.9	0.8	0.8	-0.2	-0.2	0.9
Pack years adult smoking proportion	0.4	0.6	3.6	-0.1	-0.1	0.0	-0.3	-1.4	0.9	-0.2	0.7	0.0	-0.9	0.4	0.4	-0.3	-0.0	-1.9	1.0	-1.0
Impedance of leg (right)	0.3	1.6	5.3	0.5	1.7	-0.4	1.0	-0.3	0.4	2.0	2.3	2.1	-1.3	1.3	1.5	-0.5	1.5	0.2	1.0	-0.1
Leg fat-free mass (left)	0.2	1.1	4.1	-0.3	-1.1	-0.5	-1.3	-0.6	-0.4	-2.0	-1.8	-1.5	1.0	-1.1	-1.1	0.4	-1.4	-0.2	-0.7	-0.2
Trunk fat percentage	0.1	0.6	2.5	0.8	-0.9	-0.3	-0.3	-1.6	1.1	-1.2	-0.5	-0.4	0.7	-0.3	-0.2	-0.0	-0.8	-0.9	-0.1	-0.1
Hand grip strength (right)	0.1	0.3	2.1	-0.0	0.2	-0.7	-0.4	0.3	-1.5	0.2	-0.1	0.1	1.3	-0.4	-0.0	-0.5	0.1	0.3	-0.0	-0.4
Townsend deprivation index at recruitment	0.2	0.3	0.9	-0.2	-0.9	0.6	0.2	0.6	0.4	-0.8	-0.7	-0.6	-0.6	-0.4	-0.9	0.7	-0.5	0.1	0.0	0.4
Current tobacco smoking	0.6	1.0	3.7	0.1	-1.2	-0.6	-1.2	-0.4	-0.5	-0.9	-0.6	-0.8	-1.9	-1.2	-1.3	-0.5	-1.2	-1.6	-0.3	-1.3
Average weekly fortified wine intake	0.9	1.0	2.6	0.8	-0.5	-1.0	-1.3	-0.8	1.6	-1.6	-0.9	-1.2	-0.2	-0.6	-0.2	-0.9	-1.0	-1.3	-0.2	-1.4
Maternal smoking around birth	0.2	0.3	1.3	-1.1	-0.7	-0.1	-0.1	0.9	-0.2	-0.3	-0.6	-0.5	-0.6	-0.4	-0.5	-0.4	-0.5	-0.2	-0.3	-0.0
Fed-up feelings	0.8	1.4	5.4	-0.1	-1.5	-0.8	-1.1	-1.6	-0.3	-0.9	-0.2	-0.6	-1.6	-0.9	-0.8	-1.0	-0.9	-2.3	-1.3	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	4.7	0.3	-0.7	-0.1	-0.3	-2.2	-0.6	-1.2	-0.2	-0.1	-0.4	-0.2	-0.3	0.4	-0.7	-1.2	-0.5	-0.9
Relative age voice broke	0.4	0.6	2.1	0.4	0.4	-0.5	-1.0	0.2	-0.8	-0.5	-0.7	-0.2	-1.5	-1.3	-0.9	0.6	-0.4	1.1	0.1	-0.0
Taking other prescription medications	1.2	1.8	6.9	0.4	1.2	0.9	1.1	-2.6	0.7	1.2	1.4	1.3	1.4	1.3	1.9	1.1	1.5	0.4	1.5	1.5
Age when periods started (menarche)	0.2	0.4	1.4	-0.4	-0.5	-0.5	-1.0	-0.1	-0.6	-0.6	-0.9	-0.8	-0.5	-1.2	-0.8	-0.3	-0.6	-0.4	-0.1	-0.5
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	6.9	0.4	-0.0	-1.4	-0.9	-0.3	0.8	0.7	0.6	0.2	0.3	-0.3	0.3	-2.6	-0.1	-1.8	1.0	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.8	0.3	-0.5	-1.7	-1.0	0.6	0.2	-0.1	-0.7	-0.8	1.5	-1.3	-0.7	-1.4	-0.5	-1.1	0.4	-1.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.6	-0.3	-0.1	-1.6	-0.9	-0.5	0.0	-0.1	-0.2	0.1	-0.2	-0.7	-0.6	-0.8	-0.6	-0.3	0.2	-0.2
Qualifications: CSEs or equivalent	0.5	0.6	3.6	1.9	0.4	-0.0	0.1	-1.6	-0.3	0.5	0.5	0.2	1.0	0.0	0.6	0.4	0.4	-0.5	1.2	0.5
Serious illness, injury or assault to yourself	0.4	0.5	2.4	-0.2	0.6	-0.0	-0.2	0.4	1.2	-0.7	-0.4	-0.5	1.6	0.7	0.8	0.3	0.0	0.7	0.5	0.6
High blood pressure	1.0	2.7	6.6	1.0	2.4	0.8	0.8	-2.6	0.7	1.1	1.5	2.0	0.4	1.4	2.0	1.5	1.8	2.3	1.6	2.3
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.5	1.1	-0.4	-0.8	-0.7	-0.3	-1.6	0.2	-0.5	-0.0	1.4	-1.3	-0.5	-1.1	-0.3	0.3	0.0	-0.3
Multivitamins +/- minerals	1.3	1.7	6.1	0.4	-1.2	-0.7	-1.2	0.7	1.3	-2.5	-1.9	-1.6	-0.6	-1.2	-2.0	0.4	-2.0	-0.3	-0.4	-0.6
Stomach or abdominal pain in last month	2.0	2.5	5.0	-1.6	-2.1	-1.1	-0.8	0.5	-0.8	-2.0	-2.2	-2.2	0.9	-1.6	-2.0	0.1	-1.8	-1.1	-2.0	-1.5
Supplements: Glucosamine	0.3	0.4	1.1	0.6	-0.9	-1.0	-0.4	-0.4	0.7	-0.5	-0.5	-0.4	0.5	-0.7	-0.5	-1.0	-0.5	-1.0	-0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.7	-0.6	-0.8	-0.2	0.4	-0.2	0.1	-0.3	-0.0	-0.1	0.1	-0.2	-0.7	0.5	-0.6	-0.6	0.2	-0.3
Medication: Atenolol	1.4	1.8	8.9	3.0	0.5	-0.2	0.1	-2.7	-0.6	-0.2	-0.0	0.2	2.5	0.1	1.2	0.4	0.5	0.4	1.7	1.3
Medication: Levothyroxine sodium	0.6	1.1	3.2	1.8	0.7	0.7	1.2	0.4	1.5	1.0	0.8	1.1	1.1	1.3	0.8	-0.4	0.9	1.2	-0.4	1.1
Sitting height	0.1	0.4	2.1	-0.7	0.5	-0.8	-1.4	0.2	-0.7	-0.4	-0.5	-0.4	-1.0	-0.7	-0.5	0.0	-0.5	0.1	-0.5	-0.6
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	-0.3	0.3	-0.1	-0.9	-1.5	-1.0	-1.2	-0.8	-0.9	0.3	-0.5	0.3	0.9	0.0	-0.0	0.1	-0.5
High blood pressure (mother)	0.6	0.8	3.6	-0.4	-0.3	-0.7	-1.5	-1.9	0.3	-1.3	-0.8	-1.2	-0.6	-0.5	-0.3	0.2	-0.5	-1.2	-0.8	-0.9
Body mass index (BMI)	0.2	0.9	3.0	0.6	-1.2	-0.2	-0.6	-1.7	0.2	-1.7	-1.2	-1.1	1.2	-0.7	-0.5	0.3	-0.9	-0.9	-0.4	-0.1
Impedance of leg (left)	0.3	1.6	4.7	0.9	1.4	-0.1	1.2	0.1	1.0	2.0	2.2	2.0	-1.7	1.3	1.3	-0.5	1.4	0.3	0.6	0.0
Leg predicted mass (left)	0.2	1.2	4.2	-0.3	-1.1	-0.5	-1.3	-0.7	-0.3	-2.1	-1.8	-1.5	1.0	-1.1	-1.1	0.4	-1.4	-0.2	-0.7	-0.2
Trunk fat mass	0.2	0.8	2.8	0.6	-1.1	-0.4	-0.6	-1.6	0.7	-1.7	-1.0	-0.9	1.0	-0.6	-0.5	0.3	-1.1	-0.9	-0.4	-0.2
Waist circumference	0.1	0.5	2.3	0.8	-0.3	0.6	0.0	-1.5	-0.1	-1.1	-0.3	-0.5	0.8	0.2	0.3	1.1	-0.3	-0.3	0.8	0.7
Number of incorrect matches in round	0.5	0.8	1.8	0.8	-0.5	-0.6	-1.1	-0.2	1.1	-1.4	-1.0	-1.1	0.2	-0.5	-0.5	-0.8	-0.8	-0.6	-1.2	-1.4
Past tobacco smoking	0.2	0.4	2.4	0.7	0.4	0.1	0.2	1.5	1.5	0.8	0.2	0.2	0.3	0.3	0.1	-0.6	0.4	0.5	-0.5	-0.1
Alcohol usually taken with meals	0.6	1.0	3.1	-0.4	1.8	0.8	0.7	1.8	0.6	1.0	0.7	0.7	-0.0	1.0	0.8	0.4	1.3	1.7	-0.7	0.3
Nervous feelings	0.3	0.5	2.9	0.9	0.1	-1.0	-0.3	-1.0	1.7	-0.1	0.1	0.2	0.7	-0.0	0.3	-1.0	-0.1	-0.5	-0.2	-0.9
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	8.2	1.1	-0.3	-1.6	-1.8	-2.9	0.4	-1.9	-0.8	-1.1	0.3	-0.5	-0.1	-0.8	-1.1	-1.9	-1.0	-1.9
Hearing difficulty/problems with background noise	0.1	0.2	0.7	-0.3	-0.2	0.4	0.5	-0.9	0.8	0.3	0.3	0.4	0.6	0.5	0.2	0.3	0.2	0.0	-0.5	0.4
Hair/balding pattern: Pattern 2	0.5	0.6	2.8	-0.9	0.8	0.5	0.6	1.7	0.4	0.7	0.2	0.4	1.2	0.4	0.5	0.1	0.8	1.4	0.1	0.8
Had menopause	0.2	0.3	0.9	-0.2	-0.6	-0.1	-0.5	-0.1	-0.4	-1.0	-0.5	-0.5	-0.7	-0.4	-0.1	-0.6	-0.5	-0.7	-0.4	-0.8
Had other major operations	1.1	1.4	2.8	0.8	1.2	0.7	0.9	-0.3	-1.5	1.5	1.3	1.5	0.5	1.3	1.7	-1.1	1.6	1.0	0.4	1.2
Forced vital capacity (FVC)	0.9	3.3	5.8	-0.9	-1.6	-1.9	-2.1	2.1	0.3	-2.0	-2.2	-2.2	-0.9	-1.6	-2.1	-1.9	-2.1	-1.4	-2.4	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.9	-0.6	-1.5	-2.0	-1.4	1.4	0.1	-0.8	-1.3	-1.3	1.0	-1.8	-1.8	-1.8	-1.5	-1.6	-0.1	-1.9
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	9.2	-1.4	-3.0	-0.6	-0.1	0.0	1.9	-1.5	-1.5	-1.6	0.3	-1.4	-2.0	-0.5	-1.9	-2.0	-1.7	-1.4
Qualifications: None of the above	1.2	2.7	13.8	1.9	1.2	0.8	0.9	-3.7	2.3	-0.4	0.8	1.2	-0.4	1.1	0.9	2.8	0.2	1.1	1.6	1.9
Financial difficulties in last 2 years	1.6	2.1	8.5	-1.5	-1.4	0.2	-1.0	-0.9	-0.9	-1.9	-1.8	-1.7	-1.2	-1.4	-1.7	1.5	-1.0	-0.2	-2.9	-1.0
Mouth/teeth dental problems	0.5	0.8	7.7	-1.4	-0.6	0.6	0.2	2.8	0.4	0.2	-0.8	-1.0	0.7	-0.7	-0.6	-0.1	0.1	-0.0	0.1	-0.2
Heart attack	0.6	0.8	2.8	0.7	0.6	0.4	0.5	-1.3	1.0	0.5	0.8	0.3	1.1	0.9	1.2	0.6	0.8	-0.7	1.7	0.7
Allergy	0.3	0.7	3.0	0.0	0.5	0.6	0.7	-0.4	1.7	-0.1	0.8	0.6	-1.7	1.3	0.5	1.2	0.2	0.1	-0.1	0.5
Pain all over the body in last month	0.6	0.7	5.5	0.0	0.6	0.1	0.7	-0.8	0.9	-0.0	0.3	-0.1	2.3	0.9	1.2	0.6	0.6	-0.1	0.9	0.0
Diabetes (self-reported)	0.4	0.7	4.5	0.9	0.7	-0.1	-0.7	-2.1	0.5	-0.8	0.3	0.2	0.1	0.6	0.6	0.8	-0.5	-0.5	1.7	-0.0
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.2	-1.2	-0.9	-1.3	-1.5	1.1	-1.2	-0.9	-1.2	-1.2	0.2	-1.2	-1.1	-1.8	-1.1	-0.8	-1.1	-1.6
Medication: Ramipril	0.4	0.4	3.0	-1.7	0.0	-0.4	-0.4	0.1	1.4	-0.6	-0.4	-0.4	1.1	0.0	0.0	-0.5	-0.3	-0.1	-0.0	-0.5
Medication: Simvastatin	2.2	3.2	7.4	0.7	1.7	2.2	2.0	-1.5	0.2	1.2	1.3	1.5	1.8	1.9	1.9	2.6	1.8	2.3	1.0	2.7
Fluid intelligence score	0.6	1.3	4.2	0.3	-0.0	-1.0	-1.5	0.1	1.8	-2.0	-1.9	-1.9	0.4	-0.8	-0.8	1.0	-1.0	0.2	-0.7	-1.0
Illnesses of siblings	2.0	2.8	11.0	-2.2	-1.5	-2.4	-1.3	1.7	0.1	0.6	0.1	0.1	-1.1	-1.5	-1.6	-3.3	-1.5	-2.2	0.2	-2.4
Neuroticism score	0.4	0.8	3.0	0.9	-0.3	-0.5	-0.8	-1.7	1.2	-1.2	-0.3	-0.5	-0.8	-0.3	-0.4	0.2	-0.7	-1.2	-0.2	-1.3
Weight	0.2	0.8	3.3	0.2	-0.9	-0.3	-0.9	-1.1	0.0	-1.8	-1.4	-1.3	1.1	-0.7	-0.5	0.5	-1.0	-0.4	-0.7	-0.1
Impedance of arm (right)	0.1	0.6	2.0	-0.4	0.7	-0.1	0.7	0.9	0.1	1.4	1.3	1.3	-1.0	0.5	0.6	-0.6	0.8	0.3	0.7	0.1
Arm fat percentage (right)	0.1	0.5	2.7	0.6	-0.8	0.3	0.1	-1.6	0.4	-1.1	-0.6	-0.5	0.8	-0.2	-0.2	0.8	-0.5	-0.3	-0.1	0.6
Trunk fat-free mass	0.1	0.4	1.4	-0.4	-0.2	0.0	-0.4	-0.6	-0.7	-1.1	-0.9	-0.6	1.2	-0.3	-0.3	1.0	-0.5	0.7	-0.4	0.4
Hip circumference	0.1	0.6	2.0	-0.1	-0.9	-0.0	-0.5	-0.3	-0.3	-1.4	-1.1	-1.1	1.1	-0.2	-0.4	-0.2	-0.8	-0.7	-1.1	-0.4
Time employed in main current job	0.6	0.7	3.1	1.8	0.4	0.7	0.8	-0.2	-1.2	0.8	0.5	0.4	1.0	0.3	0.5	0.8	0.8	0.5	0.9	0.9
Alcohol intake versus 10 years previously	0.8	1.1	6.0	2.0	0.2	-0.4	-1.3	-2.5	0.5	-1.6	-0.5	-0.7	-1.2	-0.2	0.4	0.1	-0.2	-0.9	-0.3	-1.1
Father’s age at death	0.5	0.7	2.5	-0.2	1.2	0.5	0.3	1.3	-1.6	0.7	0.3	0.4	0.7	0.4	0.6	0.5	0.8	1.5	0.6	0.6
Worrier / anxious feelings	0.3	0.5	4.7	0.6	0.4	-0.4	-0.5	-2.2	0.8	-0.7	0.3	0.0	0.5	0.6	0.4	0.4	-0.3	-0.6	-0.5	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	6.2	1.3	0.1	-1.0	-0.6	-2.5	0.5	-0.5	0.6	0.0	0.2	0.4	0.8	-0.7	-0.3	-2.3	0.9	-1.2
Falls in the last year	0.4	0.5	2.4	0.9	-0.4	-0.1	0.4	-1.6	1.1	0.3	0.6	0.3	0.9	0.4	0.8	-0.8	0.2	-1.0	-0.0	-0.8
Hair/balding pattern: Pattern 3	0.8	1.2	2.8	0.7	0.9	1.0	1.5	0.2	-1.2	1.6	1.2	1.1	0.6	1.3	1.5	-0.1	1.7	0.6	0.4	1.2
Number of live births	1.0	1.4	3.3	-1.5	-0.4	-1.8	-1.7	-0.7	-1.8	-0.7	-0.2	-0.1	-1.2	-1.2	-0.9	-1.5	-1.1	-1.3	0.0	-1.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	4.0	-0.0	-1.1	-1.6	-2.0	1.4	-0.0	-1.7	-1.8	-2.0	-0.4	-1.1	-1.4	-1.7	-1.6	-1.4	-1.7	-1.6
Pulse rate	2.1	3.6	7.6	1.7	1.7	2.2	2.3	-0.7	0.8	2.0	2.4	2.8	-1.2	2.1	1.8	1.7	2.0	2.2	1.3	2.2
Happiness	0.7	0.9	3.4	-0.8	-0.7	-0.4	-1.0	-1.1	-0.1	-0.7	-0.5	-1.0	-0.3	-0.8	0.2	-1.0	-0.1	-1.8	-0.8	-1.9
Noisy workplace	0.2	0.2	1.2	-0.4	-0.5	-0.3	-0.1	-0.2	-0.4	-0.1	-0.0	-0.2	0.8	-0.2	-0.1	-0.5	-0.3	-1.1	1.0	-0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.9	8.2	0.2	-0.2	-0.6	0.0	2.9	0.5	0.7	0.3	0.3	-0.4	0.3	-0.4	-2.0	-0.3	-0.3	-0.3	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	3.9	0.0	1.5	1.1	1.3	0.1	0.1	1.3	1.6	1.8	0.2	1.6	1.5	0.4	1.3	1.4	2.0	1.7
Mouth/teeth dental problems: Dentures	1.1	1.8	3.9	-1.1	-1.5	-2.0	-1.6	-1.8	0.5	-1.5	-1.1	-1.0	-0.5	-1.6	-1.0	-1.0	-1.7	-1.7	-0.4	-1.4
Asthma	0.7	1.4	5.2	-2.1	-0.6	-0.2	0.6	2.0	-0.9	1.3	0.1	0.2	2.3	-0.6	0.1	-1.9	0.5	-0.2	1.4	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	4.0	-1.4	-1.0	-1.4	-0.9	-0.6	0.6	-0.4	-0.2	-0.5	-0.4	-0.8	-0.9	-1.2	-1.0	-1.8	-1.2	-2.0
Medication: Cholesterol lowering	0.8	1.3	3.3	1.0	0.5	1.6	1.1	-1.2	-0.4	0.7	0.7	0.5	1.4	1.1	1.2	1.7	1.1	0.6	1.1	1.8
Depression (self-reported)	0.5	0.6	2.4	0.3	0.8	0.8	0.4	-0.4	-1.2	0.4	0.7	0.1	0.8	1.2	1.6	-0.2	1.0	-0.8	0.1	-0.3
Medication: Lansoprazole	0.3	0.3	1.3	0.2	0.4	-0.1	-0.2	-1.2	-0.4	-0.9	0.0	-0.3	0.1	0.7	0.9	0.2	-0.1	-0.5	0.7	-0.5
Prospective memory result	0.5	0.7	2.9	-0.3	0.1	1.7	1.0	-0.3	-1.0	0.2	0.3	0.2	0.3	1.0	0.3	1.7	0.4	0.6	-0.9	0.8
Lung cancer (father)	0.3	0.3	2.2	0.5	-0.5	0.3	-0.1	0.2	1.5	-0.4	-0.5	-0.7	0.9	-0.4	-0.2	0.2	-0.3	-0.5	0.5	-0.0
Illnesses of mother	1.7	2.1	6.8	-0.5	-0.0	2.2	2.6	2.6	0.4	1.9	1.0	1.0	0.5	1.0	0.5	1.1	1.3	1.1	1.4	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.4	0.1	-0.7	-1.1	-1.5	0.8	0.2	-1.4	-1.2	-1.6	-0.4	-0.8	-0.9	-0.9	-1.2	-1.1	-1.1	-1.4
Pulse wave Arterial Stiffness index	0.4	0.5	1.0	0.9	0.5	0.9	0.8	0.5	0.0	0.9	0.4	0.3	-0.9	0.2	0.5	1.0	1.0	0.7	0.4	0.8
Impedance of arm (left)	0.1	0.5	1.8	-0.7	0.2	-0.1	0.6	1.3	0.8	1.1	1.1	0.9	-0.7	0.5	0.3	-1.0	0.4	-0.3	0.2	-0.4
Arm fat mass (right)	0.2	0.7	2.8	0.5	-1.1	0.0	-0.4	-1.5	0.2	-1.7	-1.1	-1.0	0.9	-0.5	-0.5	0.7	-0.9	-0.5	-0.6	0.2
Trunk predicted mass	0.1	0.4	1.5	-0.4	-0.2	0.1	-0.3	-0.5	-0.7	-0.9	-0.8	-0.5	1.2	-0.2	-0.2	1.0	-0.4	0.8	-0.3	0.6
Standing height	0.0	0.3	0.7	-0.5	0.5	-0.5	-0.8	0.7	-0.6	-0.6	-0.6	-0.4	-0.0	-0.2	-0.2	0.5	-0.3	0.8	-0.7	-0.3
Length of working week for main job	0.9	1.0	3.3	-0.1	0.2	1.4	1.8	-0.2	1.6	0.9	1.1	1.2	0.4	1.2	0.5	1.1	0.7	0.4	0.8	1.2
Exposure to tobacco smoke at home	0.6	0.7	3.4	0.8	-0.7	-0.6	0.2	0.2	1.7	0.5	0.1	0.0	1.5	-0.0	0.2	-1.9	0.0	-1.0	-0.8	-0.4
Breastfed as a baby	1.4	1.7	4.3	-0.0	-1.4	-1.0	-1.1	0.2	-1.7	-1.6	-1.8	-1.5	-0.1	-1.8	-1.5	-0.8	-1.2	-0.7	-2.1	-1.0
Tense / ‘highly strung’	0.4	0.7	5.2	1.7	0.3	-0.6	-0.5	-2.3	0.1	-0.6	0.1	-0.1	0.5	0.3	0.7	-0.4	-0.2	-1.1	-0.3	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.4	-0.5	-0.0	0.2	1.2	-0.9	0.5	0.7	0.9	0.7	1.1	0.9	1.0	-0.4	0.6	-0.4	0.7	0.0
Hair/balding pattern: Pattern 4	0.4	0.9	5.5	1.7	0.1	-0.9	-0.9	-2.3	0.3	-1.6	-0.5	-0.3	0.2	-0.1	-0.3	0.2	-1.1	-0.3	0.0	-1.0
Birth weight of first child	0.3	0.6	1.5	-0.8	-0.0	-0.0	-0.2	1.2	-0.7	-1.0	-0.4	0.2	-0.9	-0.1	-1.1	0.8	-1.2	1.2	0.8	0.4
Peak expiratory flow (PEF)	0.7	1.6	4.6	0.9	-0.7	-1.8	-1.6	0.7	-0.7	-1.4	-1.3	-1.3	0.2	-0.8	-0.9	-2.1	-1.4	-1.2	-1.2	-1.9
Pulse wave reflection index	0.1	0.2	0.7	-0.0	-0.2	-0.3	-0.2	-0.1	0.4	0.0	-0.0	-0.4	-0.5	-0.4	0.2	-0.2	0.2	-0.8	0.8	-0.5
Ever highly irritable/argumentative for 2 days	3.3	4.0	8.6	-1.6	-2.0	-1.7	-2.0	0.4	0.7	-2.8	-2.7	-2.9	1.4	-2.0	-2.1	-0.7	-2.4	-2.0	-2.0	-2.4
Loud music exposure frequency	0.6	0.7	4.7	0.7	-1.0	-1.1	-0.4	-0.6	0.4	0.6	0.2	0.1	0.8	-0.6	0.1	-2.2	0.1	-1.2	0.1	-0.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.3	-2.0	-1.0	-0.1	0.1	2.2	-0.2	0.0	-0.3	-0.3	-1.7	-0.3	-1.2	-0.8	-0.4	-0.1	-2.3	-0.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	4.1	1.8	1.0	-0.6	-0.4	-2.0	-0.4	0.1	0.6	1.0	-0.2	0.5	0.7	-0.2	0.4	0.8	-0.3	0.3
Blood clot in the leg (DVT)	0.1	0.2	2.0	-0.5	0.1	0.1	-0.1	0.1	-0.5	0.1	0.3	-0.1	0.3	0.1	0.2	0.6	-0.1	-0.3	1.4	-0.2
Medication: Paracetamol	1.3	2.1	5.5	-0.8	-1.3	-1.9	-1.5	-1.4	0.9	-1.5	-1.1	-1.3	0.7	-1.3	-0.7	-1.9	-1.3	-2.1	-1.3	-2.4
Headache pain in last month	0.5	0.8	3.8	1.0	0.6	0.7	0.6	-1.5	1.9	-0.4	0.4	0.0	0.3	0.8	0.9	1.6	0.5	-0.0	0.5	0.3
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	5.7	-1.2	-1.3	-1.0	-0.9	2.4	-0.2	-0.9	-1.2	-1.5	-0.4	-1.1	-1.4	-1.8	-1.1	-1.4	-1.7	-2.0
Glaucoma (self-reported)	0.7	0.9	3.0	-0.5	-0.4	-0.8	-1.1	0.5	-1.7	-0.1	-0.3	-0.3	-1.6	-1.1	-1.1	-0.7	-0.9	-0.7	0.4	-1.4
Gout (self-reported)	0.7	0.9	5.9	-2.4	-0.5	1.3	1.4	1.5	0.3	0.7	0.4	0.2	0.7	0.9	0.2	0.9	0.4	0.6	0.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	7.6	2.8	0.4	-0.6	0.3	0.2	1.3	1.0	0.5	1.1	1.0	0.3	0.4	-2.0	0.3	0.5	-0.5	0.3
Medication: Amlodipine	0.4	0.5	5.2	-0.5	-0.3	0.1	-0.4	1.0	0.4	-0.2	0.2	-0.0	-2.3	0.2	-0.4	-1.1	-0.5	-0.7	0.2	-0.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.3	-0.8	-0.8	-0.8	-0.9	-0.1	-0.0	0.2	-0.4	-0.6	0.6	-1.2	-0.5	-1.5	-0.6	-1.5	0.5	-1.2
Birth weight	0.4	0.8	2.3	0.7	0.7	0.9	1.3	0.5	0.8	0.6	1.1	1.2	-0.5	1.5	0.4	1.2	0.4	0.9	0.3	0.9
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.9	1.1	-0.1	-0.3	0.1	-0.8	-1.7	0.8	0.3	0.6	0.2	-0.5	-0.1	-0.6	0.2	0.1	-0.1	-0.2
High blood pressure (siblings)	0.8	1.2	4.3	0.5	1.0	1.4	0.9	-0.7	0.2	-0.1	-0.1	0.3	0.8	0.9	0.7	2.1	0.8	2.1	-0.1	2.1
Forced vital capacity (FVC), Best measure	0.4	1.6	3.1	-0.5	-1.0	-1.3	-1.5	1.7	0.4	-1.5	-1.4	-1.8	-0.2	-0.9	-1.2	-1.3	-1.4	-1.2	-1.3	-1.6
Body fat percentage	0.1	0.6	2.8	0.9	-0.9	0.0	0.0	-1.7	1.2	-1.1	-0.5	-0.5	0.8	-0.2	-0.1	0.3	-0.6	-0.8	-0.2	0.1
Leg fat percentage (right)	0.2	0.6	4.3	1.0	-0.5	0.2	0.6	-2.1	0.9	-0.6	-0.0	0.0	1.1	0.3	0.5	0.6	0.1	-0.5	0.2	0.4
Arm fat-free mass (right)	0.1	0.5	1.9	0.0	-0.5	-0.2	-0.9	-0.7	-0.2	-1.4	-1.1	-0.9	0.7	-0.5	-0.5	0.5	-0.9	-0.0	-0.5	-0.0
Exposure to tobacco smoke outside home	0.5	0.7	1.4	-0.4	0.4	1.0	1.1	-0.8	1.2	0.7	0.9	0.7	0.9	1.1	1.1	0.4	0.9	0.3	0.2	0.7
Comparative body size at age 10	0.2	0.4	1.7	0.0	-0.0	0.5	0.7	0.7	0.1	-0.6	-0.3	-0.3	1.2	0.8	-0.0	1.3	-0.3	0.4	0.9	1.0
Number of full brothers	1.0	1.3	9.1	-0.7	0.1	1.8	1.6	-0.2	-0.0	-0.4	0.2	0.5	-1.2	0.9	-0.4	3.0	0.1	1.3	-0.1	1.4
Worry too long after embarrassment	0.3	0.4	1.8	-1.3	0.5	-1.0	-0.9	-0.5	-0.6	-0.7	-0.1	-0.2	0.1	-0.1	-0.3	0.0	-0.7	-0.2	-0.1	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.4	0.4	0.9	2.0	2.1	0.2	0.8	0.8	1.1	1.0	0.8	1.9	1.4	1.4	1.4	1.3	-0.3	0.9
Wheeze or whistling in the chest in last year	0.2	0.3	1.2	0.0	0.1	1.1	0.5	-1.1	-0.4	0.3	0.4	0.2	0.4	0.4	0.7	0.9	0.8	-0.1	0.3	0.4
Number of children fathered	0.3	0.3	1.6	-1.1	-0.7	-0.0	0.4	0.6	0.1	-0.3	-0.3	-0.3	1.3	0.1	-0.2	-0.1	-0.4	-0.3	-0.3	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	6.9	-0.9	0.9	1.4	0.8	-0.6	1.0	0.7	0.9	1.0	-2.6	0.7	0.2	2.6	0.6	1.5	0.0	1.0
Age at first live birth	0.4	0.7	3.7	-0.7	-0.9	0.3	0.5	1.9	0.8	-0.1	-0.4	-0.0	-1.6	-0.4	-1.3	-0.1	-0.5	0.4	-1.1	0.1
Pulse wave peak to peak time	0.5	0.6	1.2	-0.9	-0.6	-1.0	-0.9	-0.1	-0.1	-1.0	-0.6	-0.4	1.0	-0.3	-0.7	-1.1	-1.1	-0.6	-0.7	-0.9
Health satisfaction	0.9	1.2	3.7	-0.9	-1.1	-0.4	-0.6	0.6	1.4	-1.4	-1.3	-1.5	-0.1	-0.9	-0.7	-0.8	-0.7	-0.9	-1.9	-1.7
Shortness of breath walking on level ground	0.7	0.9	3.3	-0.1	0.3	1.0	1.2	-1.0	1.8	0.6	1.0	0.9	-1.3	1.0	0.8	1.0	0.7	0.0	0.4	0.6
Qualifications: College or University degree	0.7	2.1	6.4	0.4	-0.7	-1.9	-1.7	1.7	0.9	-1.0	-1.4	-1.6	0.9	-1.1	-0.8	-2.5	-1.1	-1.5	-0.8	-2.3
Eye problems/disorders: None of the above	0.4	0.5	2.4	-0.3	0.3	0.6	-0.1	-0.1	-1.3	-0.7	-0.5	-0.9	0.8	0.2	0.3	1.6	-0.0	-0.2	1.1	0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.9	1.1	1.4	0.0	0.0	-0.8	0.9	0.3	0.7	0.9	0.5	0.7	0.8	0.6	0.6	0.8	1.3	1.2
Emphysema/chronic bronchitis	1.1	1.3	5.4	1.0	1.5	0.4	-0.0	-2.3	-1.2	0.1	0.6	0.3	1.8	0.8	1.6	1.5	1.2	0.7	0.6	0.4
Medication for pain relief, constipation, heartburn	1.0	1.7	13.6	0.2	0.5	1.2	0.9	3.7	-1.3	1.1	0.1	0.6	-1.2	0.3	-0.5	0.3	0.5	2.1	0.2	1.7
Neck or shoulder pain in last month	0.7	1.0	4.8	0.7	-0.6	-0.6	-0.8	-2.2	0.2	-1.5	-0.3	-0.8	1.2	-0.0	0.0	0.2	-0.9	-1.8	0.3	-1.1
Medication: Blood pressure	0.3	0.5	3.4	1.0	0.6	-0.2	0.0	-1.8	0.3	0.2	0.4	0.8	0.4	0.1	0.4	0.7	0.3	0.6	1.1	1.0
Angina (self-reported)	1.5	2.0	5.8	1.2	1.0	1.2	1.2	-1.7	1.6	0.6	0.9	1.2	-0.2	1.1	1.2	2.2	1.1	1.4	2.0	2.4
Migraine (self-reported)	1.3	1.6	3.9	-0.8	-0.9	-1.0	-1.9	-0.9	0.5	-2.0	-1.5	-1.7	-0.7	-1.2	-1.2	-0.2	-1.3	-1.1	-1.3	-1.5
Medication: Ibuprofen	2.7	3.2	9.4	-1.8	-1.9	-2.1	-1.8	0.7	0.0	-1.1	-1.2	-1.8	-0.1	-1.5	-1.5	-2.4	-1.8	-3.0	-1.2	-3.1
Medication: Allopurinol	0.4	0.5	2.6	-0.5	0.3	0.8	1.0	0.2	-0.3	0.3	0.2	0.1	1.6	0.8	0.7	1.2	0.6	0.8	0.2	0.6
Medication: Omeprazole	0.4	0.5	2.7	1.1	0.2	-0.6	-0.5	-1.5	1.6	-0.8	0.1	0.1	-0.0	0.4	0.2	0.1	-0.6	-0.6	0.1	-0.9
Medication: Seretide 50 evohaler	1.1	1.3	2.8	-0.0	1.0	1.0	1.1	0.7	0.7	1.7	1.2	1.1	1.4	1.1	1.5	-0.1	1.6	0.9	1.4	1.2
Mean time to correctly identify matches	0.6	1.1	3.8	-0.5	-0.1	1.7	2.0	0.5	0.8	0.3	0.5	0.8	0.7	1.1	0.1	1.9	0.5	1.5	-0.1	1.6
Heart disease (mother)	0.8	0.9	6.2	1.3	-0.2	-1.2	-1.0	-2.5	0.7	-1.4	-0.4	-0.3	0.4	0.0	0.2	-0.5	-1.1	-0.8	0.5	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.8	-0.1	-0.8	-0.3	0.4	0.4	-1.4	0.1	-0.6	-0.1	0.8	-1.0	-0.7	-0.2	-0.1	0.5	-0.2	0.4
Whole body fat mass	0.2	0.7	3.1	0.8	-1.1	-0.2	-0.4	-1.8	0.6	-1.5	-0.9	-0.8	1.0	-0.5	-0.4	0.4	-0.9	-0.8	-0.4	0.0
Leg fat mass (right)	0.2	0.8	5.6	1.0	-0.9	-0.1	-0.3	-2.4	0.5	-1.5	-0.7	-0.6	0.7	-0.3	-0.2	0.7	-0.7	-0.7	-0.4	0.1
Arm predicted mass (right)	0.2	1.1	4.0	-0.1	-1.0	-0.5	-1.4	-0.4	-0.1	-2.0	-1.7	-1.5	0.3	-1.1	-1.2	0.4	-1.5	-0.2	-1.0	-0.4
Pulse rate, automated reading	2.9	9.4	17.5	2.4	3.9	2.7	2.7	-2.5	-0.5	3.1	3.7	4.2	0.1	3.5	3.8	2.4	3.5	3.5	2.7	3.6
Alcohol intake frequency.	0.5	1.1	3.8	0.2	1.1	-0.1	-0.8	-1.9	2.0	-1.1	-0.3	-0.9	1.6	0.7	1.6	0.2	0.3	-0.8	1.1	-0.6
Comparative height size at age 10	0.2	0.9	2.2	-0.3	-0.8	-1.3	-1.3	-0.3	-0.5	-1.5	-1.1	-0.7	-0.2	-1.0	-1.3	-0.1	-1.5	-0.1	-1.3	-1.0
Number of full sisters	0.2	0.3	0.7	-0.7	-0.6	0.4	-0.2	-0.2	-0.4	-0.3	-0.4	-0.4	-0.2	-0.8	-0.8	0.7	-0.0	0.1	-0.8	-0.5
Suffer from ‘nerves’	0.2	0.4	1.7	1.3	0.7	0.7	0.4	-0.6	0.5	0.3	0.7	0.5	0.7	0.7	0.8	0.2	0.6	-0.0	0.3	-0.2
Overall health rating	0.9	1.9	5.9	2.1	1.0	1.4	1.3	-2.4	0.1	0.6	1.4	1.1	1.1	1.8	1.9	1.3	1.3	0.1	1.0	1.3
Chest pain or discomfort	0.6	0.9	4.2	1.1	0.6	0.6	0.7	-2.0	0.6	0.6	0.9	0.8	1.0	1.0	1.2	0.8	0.9	0.2	0.9	0.9
Had major operations	0.9	1.1	2.3	1.2	0.5	1.3	1.3	-0.4	-0.5	0.5	0.6	0.7	0.9	1.5	1.4	0.6	1.2	1.1	-1.3	1.4
Age at last live birth	0.6	0.9	7.4	-0.7	-1.0	0.2	0.2	0.9	-0.1	0.1	-0.0	0.5	-2.7	-0.8	-1.7	-0.2	-0.6	0.3	-1.2	-0.1
Family relationship satisfaction	0.3	0.3	2.6	-0.6	0.2	0.8	-0.1	0.2	0.5	0.5	0.4	0.1	-1.6	0.0	-0.0	-0.1	0.6	-0.2	-1.0	-0.5
Leg pain on walking	2.5	3.1	10.5	-0.1	-2.0	-1.5	-1.8	-0.9	0.7	-2.1	-1.6	-2.2	0.5	-1.5	-1.2	-1.9	-1.8	-3.2	-1.0	-2.8
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	4.5	-0.1	-0.7	-0.2	-0.5	0.2	-1.8	-0.0	-0.6	-0.4	-2.1	-1.2	-1.1	-0.1	-0.0	0.1	-1.5	-0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	4.1	0.3	-0.2	0.5	0.8	-2.0	1.3	0.4	1.0	1.7	-1.3	0.1	-0.4	0.7	-0.1	0.6	-0.2	0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.4	0.5	-0.5	-0.4	0.5	-1.2	-0.0	0.9	1.0	1.0	0.4	0.2	0.3	-0.9	-0.0	-0.9	1.0	-0.3
Medication: Aspirin	1.4	1.9	11.3	2.0	1.3	0.1	0.2	-3.4	1.0	0.0	0.5	0.6	1.3	0.7	1.6	1.4	0.9	0.5	1.9	1.5
Supplements: Vitamin C	0.8	1.0	2.3	0.4	0.4	1.5	1.5	0.7	0.4	0.9	1.1	1.4	-1.1	0.9	0.1	1.1	0.7	1.3	0.5	1.2
Knee pain experienced in last month	0.3	0.4	2.1	1.2	0.0	0.0	0.1	-1.5	1.4	-0.4	-0.0	0.3	0.4	0.1	0.1	0.0	0.0	0.2	-0.9	-0.3
Hypertension (Self-reported)	0.6	1.6	3.9	0.5	1.8	0.5	0.6	-1.9	0.9	0.7	0.9	1.4	0.4	1.0	1.5	1.1	1.4	2.0	1.0	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.3	-1.4	-1.2	0.0	-0.2	0.8	-0.9	-0.7	-0.9	-0.7	-1.1	-1.1	-1.8	0.6	-1.0	-0.1	-1.2	-0.9
Illnesses of father: Heart disease	0.6	0.8	6.6	-0.2	-0.3	0.5	0.1	-0.7	2.6	-0.6	0.2	-0.4	-1.3	0.9	0.9	-0.2	0.0	-1.3	0.3	0.1
Illnesses of siblings: Diabetes	0.7	0.8	3.1	1.4	0.7	1.3	0.8	-0.4	-0.9	0.1	0.2	0.2	-0.7	0.7	0.7	1.8	0.8	0.9	-0.2	1.5
Smoking status: Previous	0.3	0.4	1.4	-0.9	0.0	0.3	0.6	-0.7	-1.1	-0.0	0.1	0.3	0.4	0.2	0.2	1.2	0.1	0.5	1.0	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.6	0.3	-0.7	-1.4	-1.9	0.2	0.1	-1.2	-1.5	-1.3	-1.5	-1.6	-1.8	-0.2	-1.3	-0.2	-1.9	-1.1
Whole body fat-free mass	0.1	0.6	2.0	-0.3	-0.6	-0.1	-0.8	-0.6	-0.6	-1.4	-1.3	-1.0	1.1	-0.6	-0.6	0.7	-0.9	0.4	-0.5	0.2
Leg fat-free mass (right)	0.2	1.1	3.7	-0.2	-1.2	-0.3	-1.2	-0.3	-0.2	-1.9	-1.8	-1.5	0.6	-1.2	-1.2	0.3	-1.4	-0.1	-0.9	-0.1
Arm fat percentage (left)	0.2	0.7	2.2	0.2	-1.3	0.1	-0.2	-1.3	0.8	-1.5	-0.9	-0.9	0.8	-0.5	-0.6	0.4	-0.9	-0.9	-0.5	-0.0
Average weekly red wine intake	0.4	0.5	4.2	2.0	0.0	-0.5	-0.8	-0.8	0.3	-0.5	-0.3	-0.7	-0.2	-0.3	0.1	-0.2	-0.1	-1.3	-0.3	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.9	0.6	0.9	0.7	0.8	0.6	0.9	0.7	0.7	0.8	-0.5	0.7	0.5	0.3	0.5	0.9	0.5	0.5
Mood swings	1.0	1.8	6.0	1.7	-0.6	-1.9	-1.5	-1.4	1.1	-0.9	-0.2	-0.6	-0.1	-0.4	-0.2	-2.4	-0.9	-2.5	-0.7	-2.0
Loneliness, isolation	0.9	1.2	6.7	0.5	0.0	-0.3	-0.8	-2.6	1.1	-1.1	0.3	-0.6	0.0	0.3	0.7	0.1	-0.3	-2.3	0.9	-1.6
Long-standing illness, disability or infirmity	2.7	4.2	16.2	2.6	2.3	0.6	1.0	-4.0	0.5	1.6	2.0	1.6	2.4	1.8	3.2	0.9	2.4	0.2	2.2	1.5
Ever had bowel cancer screening	0.5	0.6	2.8	-0.9	-0.5	-0.0	-0.5	0.1	-0.7	-0.6	-1.1	-1.1	0.1	-0.9	-0.7	0.5	-0.2	-0.0	-1.7	-0.7
Diabetes diagnosed by doctor	0.6	1.0	4.0	1.1	1.3	0.6	0.0	-1.6	0.8	-0.1	0.7	0.5	0.6	1.0	1.1	1.3	0.4	0.3	2.0	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.5	-0.9	-0.9	-0.7	-0.5	-0.6	0.2	-0.8	0.0	0.1	-0.3	-0.6	-0.9	-0.7	-1.0	-0.9	-0.5	-1.2
Friendships satisfaction	0.5	0.7	4.7	0.1	0.7	0.4	-0.4	-1.7	0.0	-0.1	0.6	0.7	-2.2	0.3	0.5	0.2	0.4	0.2	-0.9	-0.7
Qualifications: nursing, teaching	0.8	1.2	9.9	0.6	-0.5	-0.7	-0.6	3.1	0.1	-0.2	-0.7	-0.8	0.9	-0.3	-0.7	-1.9	-0.5	-0.4	-1.1	-1.0
Commuting to job workplace: Walk	0.5	0.6	2.6	0.3	0.9	0.3	0.0	1.0	-1.6	-0.2	-0.5	-0.6	0.7	0.3	0.5	0.7	0.7	1.2	-0.8	0.4
Eye problems/disorders: Cataract	0.5	0.6	4.2	1.3	0.1	-1.0	-0.3	-0.3	2.0	-0.2	-0.1	0.1	1.3	0.3	0.1	-1.0	-0.3	-0.0	-0.7	-0.5
Mouth/teeth dental problems: Mouth ulcers	3.0	4.7	10.2	2.1	2.5	2.5	2.3	-1.5	0.1	1.9	2.9	2.5	-0.8	3.2	2.6	2.2	2.5	1.6	1.0	2.0
Medication for cholesterol	0.4	0.6	3.5	0.1	-0.9	0.3	-0.3	1.4	-1.9	-0.1	-0.7	-1.0	-0.3	-0.5	-0.9	0.1	-0.6	-0.6	-0.8	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	2.3	0.4	0.8	0.0	0.3	-0.9	0.1	0.6	0.9	0.6	1.5	0.8	1.1	-0.6	0.7	-0.3	0.7	-0.2
Back pain experienced in last month	1.1	1.5	11.7	3.4	1.0	-1.0	-0.1	-2.6	0.5	-0.1	0.4	0.5	1.9	0.5	1.0	-0.2	0.4	0.1	-0.2	-0.0
Mineral and other dietary supplements	0.8	1.1	3.8	0.3	0.3	-1.0	-2.0	0.3	-1.5	-0.6	-1.1	-1.5	0.7	-1.1	-0.1	-0.9	-0.3	-0.9	-0.6	-1.6
Breast cancer (self-reported)	0.7	0.9	3.0	0.6	0.0	-1.2	-1.7	-0.6	-0.5	-1.3	-0.9	-1.0	-1.2	-0.7	-0.4	-0.7	-1.0	-0.6	-0.6	-1.2
Asthma (self-reported)	0.7	1.3	4.8	-2.2	-1.1	-0.2	0.7	2.0	-0.8	1.1	-0.0	0.1	2.1	-0.8	-0.2	-1.9	0.2	-0.4	1.1	-0.0
Osteoporosis (self-reported)	0.6	0.8	3.2	0.7	0.8	0.3	0.7	-1.8	-1.1	1.0	1.3	1.1	0.5	0.9	1.0	0.4	0.9	0.0	0.4	0.0
Osteoarthritis (self-reported)	1.8	2.4	6.0	0.4	0.6	2.1	2.3	-0.7	2.0	1.1	0.9	0.7	2.5	1.6	1.7	1.8	1.9	1.1	-0.4	1.7
Medication: Aspirin	1.7	2.2	10.9	2.2	1.4	0.3	0.3	-3.3	0.7	0.1	0.6	0.6	1.6	0.9	1.8	1.5	1.0	0.5	2.3	1.7
Medication: Gliclazide	0.5	0.6	3.1	1.0	0.0	0.1	0.0	-1.0	1.3	-0.0	0.2	0.2	1.4	0.2	0.4	0.1	-0.2	-0.4	1.8	0.6
Illnesses of father: None of the above (group 1)	0.9	1.1	2.9	0.3	-1.3	-0.9	-0.6	1.7	-1.5	-0.1	-1.0	-0.8	0.8	-1.7	-1.5	-1.2	-0.7	-0.6	-0.9	-1.0
Smoking status: Current	0.8	1.3	3.5	0.2	-1.3	-0.8	-1.3	-0.4	-0.6	-0.8	-0.6	-0.8	-1.9	-1.4	-1.4	-1.0	-1.3	-1.8	-0.6	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	2.5	-0.3	0.2	-0.3	-0.6	0.8	1.6	-0.4	-0.1	-0.3	-0.5	0.4	0.1	-0.6	-0.4	-0.4	0.3	-0.2
Whole body water mass	0.1	0.7	2.5	-0.4	-0.7	-0.3	-1.0	-0.6	-0.5	-1.6	-1.4	-1.1	1.1	-0.8	-0.8	0.7	-1.0	0.2	-0.6	0.0
Leg predicted mass (right)	0.2	1.0	3.4	-0.1	-1.1	-0.2	-1.1	-0.2	-0.2	-1.8	-1.7	-1.4	0.7	-1.1	-1.2	0.4	-1.3	0.0	-0.8	-0.0
Arm fat mass (left)	0.3	1.1	3.8	0.1	-1.4	-0.3	-0.8	-1.4	0.4	-1.9	-1.5	-1.4	1.0	-0.9	-0.9	0.3	-1.3	-0.9	-0.8	-0.3
Number of self-reported non-cancer illnesses	0.6	1.0	3.7	0.6	0.9	0.2	0.5	-1.9	0.3	1.2	1.3	1.2	0.6	0.6	1.4	-0.2	1.1	-0.2	1.7	0.5
Average weekly champagne plus white wine intake	0.9	1.3	4.4	0.5	0.7	1.9	1.1	2.1	0.5	0.7	-0.1	0.1	-0.9	0.6	0.0	0.9	1.1	2.0	-1.5	1.4
Miserableness	0.4	0.7	2.7	0.2	-0.9	-0.3	-0.7	-0.4	1.4	-0.8	-0.4	-0.5	-1.6	-0.5	-1.1	-0.1	-0.9	-0.8	-1.1	-1.0
Guilty feelings	0.5	0.8	3.4	0.9	0.6	0.6	-0.2	-1.3	1.3	-1.5	-0.4	-0.2	-1.0	0.3	-0.5	1.8	-0.7	0.6	-0.7	-0.1
Wears glasses or contact lenses	1.5	1.7	4.7	-0.8	-1.7	-0.3	-0.6	0.7	0.2	-2.2	-2.0	-1.8	0.2	-1.0	-1.7	0.6	-1.7	-0.5	-2.0	-0.5
Ever taken oral contraceptive pill	0.4	0.5	3.1	0.8	0.6	-0.4	-0.8	-1.1	0.2	0.2	0.1	0.2	-1.8	-0.6	0.2	0.4	0.4	0.5	0.3	0.4
Hearing aid user	1.3	1.4	8.6	1.4	0.1	-1.6	-1.3	-2.9	0.7	-0.8	-0.3	-0.6	1.7	-0.2	0.6	-0.7	-0.5	-1.7	0.3	-1.0
Mother’s age at death	0.1	0.2	0.8	0.1	0.2	-0.0	0.2	0.8	-0.1	0.1	-0.2	0.1	0.6	0.1	-0.3	0.2	0.1	0.9	-0.4	0.5
Financial situation satisfaction	3.2	4.0	7.2	-1.2	-2.2	-2.0	-2.0	-0.6	-2.2	-2.7	-2.3	-2.3	-0.0	-1.8	-1.8	-1.6	-2.4	-2.0	-2.7	-2.3
Tinnitus: Yes, now most or all of the time	2.0	2.4	5.9	0.7	-1.0	-1.8	-2.1	-1.6	1.3	-2.4	-1.4	-1.7	-0.9	-1.2	-0.7	-0.9	-1.7	-2.0	-0.6	-2.4
Commuting to job workplace: Public transport	0.6	0.7	4.4	-0.5	0.5	0.1	0.1	2.1	0.2	-0.2	-0.7	-1.0	1.8	0.4	0.1	0.7	0.3	0.9	-0.3	-0.0
Eye problems/disorders: Glaucoma	0.9	1.1	4.7	-1.2	-1.1	-0.2	-0.3	1.8	-1.8	0.1	-0.2	-0.2	-2.2	-0.6	-1.5	-0.6	-0.9	-0.4	-0.6	-0.8
Medication: Blood pressure	0.7	1.4	5.9	-0.3	1.4	0.8	0.7	-2.4	1.1	0.3	0.9	1.2	0.5	0.9	1.5	1.3	1.5	1.3	0.7	1.1
Pain type(s) experienced in last month: Hip pain	2.0	2.5	7.8	2.8	1.3	1.5	1.4	-2.4	-0.4	1.3	2.0	1.9	-0.4	1.7	1.8	0.9	1.4	0.3	1.7	1.3
Supplements: Fish oil (including cod liver oil)	1.3	1.7	4.3	-0.6	-0.2	1.2	2.1	-1.4	1.9	0.3	1.2	1.9	-1.1	1.4	0.4	1.8	0.3	1.4	0.4	1.9
High cholesterol (Self-reported)	0.2	0.4	1.3	-0.7	0.6	0.8	0.1	-1.1	-0.1	0.3	0.4	0.2	0.3	0.5	0.6	0.9	0.5	0.2	0.6	0.9
Medication: Bendroflumethiazide	1.7	2.6	8.8	1.0	1.8	0.9	0.9	-3.0	1.8	1.5	1.9	2.2	-0.4	1.2	1.7	1.4	1.7	1.4	1.2	1.6
Medication: Paracetamol	1.6	2.4	8.2	-1.2	-1.7	-1.8	-1.2	-0.5	0.6	-1.5	-1.0	-1.5	1.1	-1.2	-0.6	-2.4	-1.4	-2.9	-0.3	-2.6
Medication: Lisinopril	1.3	1.6	5.0	1.3	1.7	0.3	0.5	-1.0	-2.0	1.1	1.0	1.4	0.9	0.7	1.2	0.8	0.9	1.4	2.2	1.6
Medication: Atorvastatin	0.2	0.3	1.5	0.1	0.2	-0.7	-0.6	-0.9	-0.7	-0.3	-0.1	-0.1	-0.5	-0.2	0.1	0.0	-0.2	-0.3	1.2	0.1
Illnesses of father: High blood pressure	1.3	1.6	3.8	0.3	1.5	1.5	1.5	-0.7	0.7	0.9	1.0	1.3	-0.5	1.4	1.2	1.8	1.4	2.0	0.6	1.9
Alcohol drinker status: Never	0.7	0.9	1.7	-0.1	-1.0	-1.1	-0.8	0.2	1.1	-1.3	-1.3	-1.2	0.7	-1.0	-1.1	-0.8	-1.2	-0.8	-0.4	-0.9
Ever smoked	0.4	0.6	3.7	-0.5	-0.2	0.2	-0.3	-1.9	-1.8	-0.9	-0.3	-0.4	-0.8	-0.2	0.0	1.0	-0.2	-0.5	0.1	-0.2
Basal metabolic rate	0.1	0.7	2.7	-0.3	-0.7	-0.3	-0.9	-0.7	-0.4	-1.6	-1.4	-1.2	1.1	-0.8	-0.7	0.6	-1.0	0.2	-0.6	0.1
Leg fat percentage (left)	0.2	0.6	3.6	1.3	-0.6	0.5	0.7	-1.9	1.0	-0.7	-0.1	-0.0	0.9	0.3	0.4	0.7	0.0	-0.4	-0.0	0.5
Arm fat-free mass (left)	0.1	0.7	2.5	0.1	-0.3	-0.5	-1.1	-0.8	-0.2	-1.6	-1.4	-1.1	0.7	-0.8	-0.7	0.6	-0.9	0.4	-0.6	0.0
Number of operations (self-reported)	1.4	2.1	4.7	0.2	0.7	1.4	2.1	-0.3	1.0	1.9	1.9	2.0	0.7	2.2	1.9	-0.3	1.8	1.1	-0.2	2.0
Average weekly beer plus cider intake	0.1	0.2	0.7	-0.8	-0.1	0.4	0.7	0.6	-0.5	0.3	0.3	0.2	0.4	0.8	0.4	-0.1	0.2	0.2	-0.1	0.2
Irritability	0.1	0.3	1.5	0.7	0.4	0.3	0.1	0.5	1.2	-0.2	-0.0	-0.2	-0.2	1.0	0.4	-0.2	0.1	0.2	-0.4	0.5
Risk taking	0.8	1.1	9.3	0.1	-0.8	-0.1	-0.9	0.4	3.0	-0.7	-1.0	-1.2	0.2	-1.0	-1.3	0.3	-0.9	-1.0	-0.8	-0.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	4.9	-0.9	-1.1	-0.5	-0.1	-1.2	0.6	-0.4	0.1	0.2	-2.2	-0.7	-1.0	-0.0	-0.7	-0.9	-1.4	-0.8
Fractured/broken bones in last 5 years	0.6	0.7	4.4	0.2	-0.3	-1.5	-0.7	-2.1	-0.6	-0.8	-0.1	-0.0	1.4	-0.3	0.1	-0.3	-0.9	-0.8	0.7	-0.4
Age started oral contraceptive pill	1.0	1.2	4.0	-0.5	1.5	2.0	0.5	1.0	-0.9	0.6	0.8	0.2	-0.3	1.7	1.9	0.5	1.4	0.5	0.6	0.9
Diastolic blood pressure, automated reading	0.8	2.5	8.4	1.8	2.0	1.3	1.7	-0.8	-0.6	0.9	1.2	1.8	0.4	1.7	1.6	1.9	1.5	2.9	0.3	2.0
Ever depressed for a whole week	1.3	1.6	4.7	-2.1	-2.2	-0.8	-0.2	-0.7	0.1	-1.4	-1.2	-1.4	-0.3	-0.9	-1.3	-0.3	-1.5	-2.1	-0.9	-1.3
Unable to work because of sickness or disability	0.5	0.6	4.4	0.3	0.1	0.3	0.4	-0.9	0.7	-0.4	-0.1	-0.4	2.1	0.5	0.7	1.0	0.1	-0.4	1.2	0.5
Commuting to job workplace: Cycle	0.5	0.6	3.3	-1.7	0.4	0.3	-0.9	0.9	-1.8	-0.3	-0.8	-1.1	0.2	-0.4	0.1	0.2	0.1	0.1	-0.1	-0.3
Myopia	1.3	1.8	4.4	-0.3	-0.5	-0.3	-2.0	0.5	-0.4	-2.1	-1.8	-1.9	-2.0	-1.4	-1.6	0.8	-1.4	-0.3	-1.4	-1.3
Vascular/heart problems diagnosed by doctor	1.8	5.0	10.9	-1.6	-3.1	-1.1	-1.4	3.3	-1.1	-1.7	-2.3	-2.8	-0.7	-2.1	-2.8	-1.8	-2.4	-2.6	-2.4	-2.8
Cholesterol lowering medication	0.6	0.9	3.8	0.1	1.8	0.1	-0.2	-1.9	1.2	-0.2	0.4	0.7	-0.2	0.4	0.9	1.3	0.6	1.3	0.8	0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.7	0.6	-0.2	-0.6	-0.7	-1.7	1.1	-0.8	-0.0	-0.3	0.0	0.0	0.1	0.1	-0.6	-1.2	0.3	-1.1
Pain experienced in last month	0.5	0.8	6.0	-1.8	-0.2	0.0	0.1	2.4	-0.5	1.1	0.2	0.5	-0.8	-0.5	-0.5	-1.3	0.3	0.5	0.1	0.3
Supplements: Calcium	0.4	0.4	1.5	0.4	0.3	1.2	0.9	-0.5	0.3	0.5	0.4	0.4	-0.8	0.2	0.2	1.2	0.7	0.4	0.1	0.7
Basal cell carcinoma (self-reported)	0.5	0.6	4.9	-0.9	-0.9	-0.1	1.0	0.4	-1.0	0.1	-0.3	0.0	2.2	-0.0	-0.5	0.3	-0.4	0.3	-1.0	-0.1
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.8	0.7	0.8	0.7	0.8	-1.4	0.8	0.7	1.0	0.7	0.9	1.2	1.4	0.9	1.0	-0.3	1.7	1.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.8	-0.4	0.3	-0.2	-0.6	-0.1	-0.8	-0.2	0.1	-0.3	0.3	-0.1	0.3	0.6	-0.1	-0.3	1.4	-0.5
Heart disease (siblings)	1.7	2.0	12.8	2.1	0.7	-0.6	-1.4	-3.6	-0.8	-1.8	-0.8	-1.4	1.8	0.1	1.2	1.1	-0.2	-1.2	0.6	-0.3
Alcohol drinker status: Previous	0.9	1.1	3.6	0.9	1.2	0.4	0.3	-1.5	-0.2	0.2	0.7	0.1	1.5	1.2	1.9	0.7	1.0	-0.6	1.9	0.2
Pack years of smoking	0.4	0.6	4.2	0.1	-0.0	-0.0	-0.3	-1.2	1.0	-0.2	0.6	-0.0	-1.0	0.3	0.4	-0.4	-0.1	-2.0	1.2	-1.0
Impedance of whole body	0.2	1.2	3.5	0.0	1.3	-0.1	0.9	1.1	0.7	1.8	1.9	1.7	-1.3	1.2	1.0	-0.9	1.1	0.1	0.7	-0.2
Leg fat mass (left)	0.2	0.8	5.1	1.1	-1.0	-0.0	-0.2	-2.3	0.7	-1.4	-0.8	-0.6	0.6	-0.4	-0.2	0.7	-0.7	-0.6	-0.5	0.2
Arm predicted mass (left)	0.1	0.5	1.5	-0.2	-0.3	-0.3	-0.9	-0.6	-0.5	-1.2	-1.2	-0.9	0.6	-0.7	-0.6	0.6	-0.7	0.5	-0.5	0.2