TWAS hub - CNN2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1430	0.0340	5.0e-06	0.073	0.065	0.075	0.077	0.071	3.5e-09	2.5e-08	2.1e-09	1.2e-09	5.7e-09
2	GTEx	Adipose Subcutaneous	0.1240	0.0450	6.7e-03	-0.003	NA	-0.003	NA	-0.003	9.7e-01	NA	6.4e-01	NA	7.7e-01
3	GTEx	Cells Transformed fibroblasts	0.2230	0.0500	9.0e-06	0.184	NA	0.148	NA	0.163	8.8e-14	NA	3.2e-11	NA	2.7e-12
4	GTEx	Esophagus Muscularis	0.3800	0.0680	2.1e-06	0.035	NA	0.062	NA	0.078	3.4e-03	NA	1.2e-04	NA	1.9e-05
5	GTEx	Pituitary	0.7820	0.1040	5.3e-04	0.017	NA	-0.008	NA	0.029	1.2e-01	NA	5.9e-01	NA	6.3e-02
6	GTEx	Thyroid	0.2230	0.0550	9.6e-05	0.109	NA	0.078	NA	0.090	1.1e-08	NA	1.4e-06	NA	2.1e-07
7	GTEx	Whole Blood	0.1540	0.0390	4.4e-05	0.086	NA	0.053	NA	0.060	2.3e-08	NA	1.1e-05	NA	3.0e-06
8	NTR	Blood	0.0427	0.0117	1.8e-08	0.038	0.026	0.031	0.033	0.034	2.3e-12	6.0e-09	2.0e-10	8.5e-11	3.1e-11
9	YFS	Blood	0.2565	0.0316	0.0e+00	0.054	0.121	0.142	0.145	0.095	5.1e-17	1.5e-37	5.6e-44	4.3e-45	1.7e-29
10	TCGA	Esophageal Carcinoma	0.1260	0.0630	9.9e-03	-0.007	0.026	-0.006	NA	-0.007	6.4e-01	5.1e-02	5.8e-01	NA	6.2e-01
11	TCGA	Brain Lower Grade Glioma	0.0481	0.0207	6.2e-04	0.035	0.030	0.024	NA	0.025	6.8e-05	2.0e-04	8.1e-04	NA	7.5e-04
12	TCGA	Thyroid Carcinoma	0.0920	0.0330	2.4e-05	0.033	0.066	0.052	NA	0.032	3.6e-04	5.4e-07	8.2e-06	NA	3.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Blood White Count	9.2	67.9	136.9	-10.7	-10.8	-10.4	-8.1	2.2	-8.7	-4.0	-1.1	-7.8	1.8	-10.6	-11.7
Wheeze or whistling in the chest in last year	4.7	8.4	19.5	3.9	3.4	3.5	2.2	0.3	3.3	2.9	0.6	1.5	0.4	3.9	4.4
Respiratory disease	4.4	9.9	19.3	3.6	4.4	4.2	2.6	1.3	4.0	0.3	-1.9	-0.3	-2.9	3.9	4.1
Asthma	3.7	7.2	18.5	3.0	4.3	4.3	2.0	1.4	3.0	0.3	-2.3	-0.3	-2.0	2.3	3.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.7	7.8	15.2	-2.1	-2.7	-2.8	-3.0	-1.1	-3.6	-3.3	0.2	-3.5	-1.0	-3.9	-3.5
Asthma (self-reported)	3.6	7.1	18.2	2.8	4.3	4.2	2.1	1.3	3.0	0.3	-2.2	-0.2	-1.9	2.4	3.4
Medication: Gliclazide	3.5	4.0	7.9	2.7	2.8	2.6	2.4	-0.5	2.6	1.0	-0.6	0.8	-0.9	2.5	2.0
Depression (self-reported)	3.1	3.7	8.2	2.0	2.5	2.9	1.8	-0.1	2.5	1.0	-1.6	1.5	-0.7	1.9	2.6
Number of full brothers	2.9	3.7	9.9	-1.2	-2.6	-2.2	-3.1	1.1	-2.2	-0.1	0.1	-1.1	1.3	-3.0	-1.8
Alzheimer’s Disease (in father)	2.7	2.9	19.6	-0.7	-0.5	-0.3	-0.4	-0.7	0.3	4.4	0.1	2.6	2.4	0.5	0.9
Medication: Ventolin 100micrograms inhaler	2.7	3.5	8.6	2.0	1.9	1.8	1.6	0.5	2.3	0.6	-2.9	1.3	-1.8	2.3	2.0
Alzheimer’s Disease (including proxy)	2.5	3.7	24.5	-0.8	0.0	0.0	0.2	-0.6	1.0	5.0	-0.2	2.5	1.0	2.3	2.2
Medication: Bendroflumethiazide	2.5	3.8	8.1	2.5	2.6	2.9	1.8	1.3	2.2	1.0	-0.4	0.9	-0.2	2.1	2.7
Lupus	2.3	3.4	10.3	2.4	0.4	0.8	1.2	-0.0	1.7	1.9	3.2	1.7	2.3	1.7	2.3
Health satisfaction	2.3	3.0	9.6	2.2	3.1	3.1	1.8	0.0	1.4	-0.4	-0.9	0.8	-1.0	1.1	2.0
Medication for cholesterol	2.3	3.5	7.2	-2.6	-2.3	-2.5	-1.3	-1.1	-1.8	-1.6	-0.1	-1.9	-0.9	-1.9	-2.7
Mineral and other dietary supplements	2.3	3.1	7.9	1.0	1.1	1.3	0.5	0.6	2.0	2.8	0.9	2.7	1.8	2.3	2.0
Hair/balding pattern: Pattern 3	2.2	3.2	8.4	-2.5	-2.7	-2.9	-1.9	-1.1	-1.9	-0.3	1.2	-0.8	0.3	-2.1	-1.4
Basal cell carcinoma (self-reported)	2.2	2.7	8.0	-1.8	-1.6	-1.5	-2.3	-1.1	-2.1	-1.3	-0.1	-0.8	0.2	-2.8	-1.7
Crohns Disease (2017)	2.0	4.5	16.0	-2.4	-0.6	-1.0	1.0	1.9	-2.5	-2.7	-2.1	-1.4	-1.6	-1.9	-4.0
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	17.9	-1.9	-2.5	-1.9	-1.9	-1.2	-2.7	-1.2	1.0	-0.7	2.1	-4.2	-1.9
Smoking status: Previous	2.0	2.9	11.4	1.5	2.0	2.1	3.4	2.7	1.3	0.3	0.4	0.7	0.5	0.8	1.7
Irritability	2.0	3.3	9.0	-2.3	-1.5	-1.6	-1.0	0.2	-2.4	-2.3	0.2	-3.0	-0.8	-2.4	-1.6
Heart disease (siblings)	2.0	2.5	9.6	0.3	0.4	0.2	0.5	1.0	0.3	-2.3	-2.8	-2.2	-3.1	0.2	-0.0
Blood Eosinophil Count	1.9	15.0	53.3	2.6	2.9	2.5	3.1	5.7	3.6	0.4	-7.3	-1.3	-5.0	4.7	1.4
Lung FVC	1.9	9.4	20.2	-1.8	-2.5	-3.1	-0.8	-2.6	-3.2	-4.5	-1.8	-4.0	-3.4	-2.7	-4.2
Allergy	1.9	4.3	16.7	-0.2	-1.9	-1.4	-1.7	0.0	0.0	3.0	2.8	2.9	4.1	-0.4	0.5
Length of working week for main job	1.9	2.1	5.8	-2.4	-1.6	-1.7	-1.7	-0.9	-0.6	-0.7	-2.1	-0.8	-1.1	-0.9	-1.2
Eye problems/disorders: None of the above	1.8	2.1	7.2	-2.7	-0.9	-1.0	-2.2	2.1	-1.0	-0.5	-1.8	-0.0	0.4	-1.2	-1.1
Medication: Allopurinol	1.8	2.4	12.2	-0.6	0.1	-0.3	0.8	0.1	0.0	-2.8	-2.1	-1.7	-3.5	0.3	-0.7
Financial situation satisfaction	1.8	2.2	7.6	0.9	2.3	1.9	1.4	0.2	-0.0	-2.0	-0.3	-1.0	-2.8	1.4	0.7
Shortness of breath walking on level ground	1.7	2.0	3.9	1.4	1.6	1.7	2.0	1.0	1.7	1.3	-0.9	0.3	-0.6	1.8	1.6
Tinnitus: Yes, now most or all of the time	1.7	1.9	10.0	0.2	0.6	0.1	0.7	-0.9	-0.7	-3.2	-1.4	-0.5	-2.5	-0.7	-1.4
Lung FEV1/FVC ratio	1.6	8.0	18.1	-1.6	-4.2	-3.6	-2.7	-0.3	-2.2	1.4	4.0	-0.8	4.2	-2.4	-3.0
Hayfever, allergic rhinitis or eczema	1.6	3.4	11.3	-1.1	-0.1	-0.6	1.0	-0.0	-1.1	-3.4	-1.9	-2.8	-3.3	-0.5	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.2	11.2	-1.8	-2.4	-2.4	-1.0	-0.4	-2.8	-3.3	0.1	-2.8	-1.3	-2.8	-3.1
Number of operations (self-reported)	1.6	2.3	5.3	1.7	1.5	1.6	1.2	0.6	2.3	1.6	-1.3	0.9	-0.9	2.3	1.4
Medication: Metformin	1.5	2.1	5.4	1.4	1.7	1.8	2.3	1.3	1.7	1.3	-0.0	0.7	0.7	1.3	1.6
Townsend deprivation index at recruitment	1.5	2.2	5.6	2.0	2.2	2.4	1.6	0.1	1.6	0.0	-1.4	0.4	-0.8	0.7	1.8
High blood pressure (mother)	1.5	2.1	5.5	-1.7	-1.6	-1.3	-2.3	-0.3	-1.6	-1.3	-0.1	-0.9	0.2	-2.1	-1.6
Medication: Seretide 50 evohaler	1.5	1.7	4.8	1.5	1.7	2.2	1.2	0.9	1.8	0.2	0.0	-0.2	0.4	0.8	2.1
Overall health rating	1.5	3.3	7.2	2.2	2.5	2.7	2.1	0.0	1.7	0.8	0.1	1.2	-0.3	2.1	2.6
Alcohol drinker status: Never	1.5	1.8	3.9	2.0	1.5	1.8	0.5	2.0	1.5	0.9	0.1	1.6	0.8	0.8	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	12.2	-1.6	-1.9	-1.4	-1.8	-1.8	-2.5	-1.4	-0.2	-0.7	1.0	-3.5	-1.3
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.5	1.6	1.4	1.5	1.9	-1.3	1.1	-0.1	0.2	0.3	-0.6	1.4	1.4
Nervous feelings	1.4	2.7	9.3	-0.0	1.4	1.1	2.0	1.4	-0.2	-1.9	-2.8	-1.3	-3.0	0.6	-0.1
Loneliness, isolation	1.4	1.9	4.6	1.5	1.7	2.0	1.6	1.4	1.2	0.9	-0.8	0.6	-0.2	1.2	2.1
Hair/balding pattern: Pattern 2	1.3	1.6	5.9	0.8	1.7	1.6	2.4	0.2	1.2	-0.1	-0.9	0.6	-0.7	1.5	1.4
Pain all over the body in last month	1.3	1.4	4.2	1.4	-0.1	0.1	-1.7	-2.0	-0.2	1.2	1.6	0.2	1.2	-0.1	1.6
Time employed in main current job	1.3	1.5	7.8	-0.1	-1.3	-0.9	-2.8	-1.7	0.3	0.2	0.8	-0.3	1.6	-1.0	-0.4
Tense / ‘highly strung’	1.3	2.2	10.7	-0.6	0.7	-0.0	3.3	0.8	-0.3	-1.4	-1.5	-1.1	-2.7	1.2	-0.4
Forced vital capacity (FVC), Best measure	1.3	4.8	14.1	-1.6	-1.8	-1.9	-0.5	-0.7	-2.6	-3.8	-0.8	-2.6	-2.2	-2.5	-2.8
Illnesses of father: Heart disease	1.3	1.7	6.0	1.0	1.8	1.6	2.4	0.6	0.9	-1.1	-0.4	-1.2	-1.6	1.3	0.7
Irritable Bowel Disease (IBD)	1.2	2.9	8.0	-1.3	0.3	-0.0	2.2	1.8	-1.4	-2.2	-2.5	-0.4	-1.6	-1.2	-2.8
Ulcerative Colitis (UC)	1.2	2.2	8.4	1.1	2.0	1.8	2.9	0.1	1.0	-0.5	-2.1	1.1	-1.3	0.8	0.5
Primary Biliary Cirrhosis	1.2	1.7	5.9	1.0	1.3	1.1	0.8	-0.2	1.6	1.4	0.0	2.0	0.3	2.4	1.1
Blood Platelet Count	1.2	14.1	26.0	-4.8	-3.5	-3.8	-2.5	3.3	-3.1	-3.0	-5.1	-4.2	-2.7	-2.8	-5.0
Current tobacco smoking	1.2	1.9	9.1	-0.1	-1.2	-0.9	-1.2	-1.2	0.6	3.0	1.6	0.8	2.0	0.6	1.1
Taking other prescription medications	1.2	1.8	3.5	1.6	1.6	1.7	1.4	0.8	1.6	-0.4	0.5	-0.4	-1.1	1.8	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	3.8	1.7	1.4	1.5	0.7	-0.6	1.6	1.9	-0.8	1.7	0.1	1.6	1.9
Alcohol intake frequency.	1.2	2.7	5.6	2.0	2.4	2.1	0.9	2.2	0.5	0.4	-1.6	1.5	-0.9	1.9	1.9
Leg pain on walking	1.2	1.5	7.7	-0.8	-0.8	-0.9	-0.6	-0.6	-0.4	-1.5	-1.1	-2.8	-1.6	-1.0	-0.9
Friendships satisfaction	1.2	1.5	5.0	0.5	1.1	1.0	0.5	0.9	1.7	1.2	-1.1	0.8	-1.0	2.2	1.6
Osteoarthritis (self-reported)	1.2	1.6	5.2	-1.9	-2.3	-2.1	-1.6	-0.7	-1.2	0.2	-0.1	-0.2	0.2	-1.0	-0.4
Worry (Nagel 2018)	1.1	2.3	5.2	-2.3	-0.7	-0.7	0.7	2.1	-1.7	-1.4	-1.2	-2.0	-0.8	-1.6	-1.8
Alzheimer’s Disease (in mother)	1.1	1.3	5.1	-0.3	0.4	0.5	0.7	-0.2	1.5	2.2	-0.5	1.4	-0.1	1.6	1.5
Fasting Glucose	1.1	1.3	3.2	1.8	1.6	1.6	0.5	1.5	1.3	-0.9	0.2	0.3	-0.7	0.6	1.1
Hypothyroidism (self reported)	1.1	2.6	11.6	0.7	-0.3	0.2	-0.6	0.8	-0.1	2.0	3.4	0.9	3.3	-1.1	1.1
Chronotype (morning person)	1.1	2.6	9.1	-1.2	-1.2	-1.0	-0.8	0.3	-2.4	-3.0	-1.1	-0.5	-0.9	-2.7	-1.6
Supplements: Glucosamine	1.1	1.4	5.6	-0.2	-0.5	-0.6	-0.5	-0.2	-0.6	-2.3	-0.4	-2.4	-1.6	-1.1	-0.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	8.5	-1.5	-1.9	-2.0	-0.6	-0.4	-2.5	-2.9	-0.4	-2.3	-1.4	-2.1	-2.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.0	1.7	1.7	1.7	1.6	0.8	0.9	0.4	0.8	0.5	0.0	1.2	0.6
Worry too long after embarrassment	1.1	1.8	6.8	-1.5	-0.7	-0.9	-0.2	1.9	-0.5	-1.1	-0.7	-2.6	-2.1	-0.1	-0.9
Suffer from ‘nerves’	1.1	1.7	6.2	-1.2	-0.0	0.1	1.0	2.5	-0.6	-1.2	-2.0	-1.4	-0.9	-1.4	-1.0
Commuting to job workplace: Car/motor vehicle	1.1	1.2	3.6	-1.1	-1.3	-1.3	-0.3	0.9	-0.5	-1.4	-1.3	-1.3	-1.9	-0.5	-0.2
Long-standing illness, disability or infirmity	1.1	1.7	4.7	1.3	1.2	1.7	1.3	0.8	1.7	1.6	0.5	0.0	1.1	0.6	2.2
Alcohol drinker status: Previous	1.1	1.3	4.3	1.0	1.2	1.3	0.5	0.9	0.2	-0.2	-1.6	0.5	-1.6	0.7	2.1
Stomach or abdominal pain in last month	1.0	1.2	3.8	-1.7	-0.6	-0.6	0.4	2.0	0.3	1.5	-1.0	1.6	0.7	-0.2	0.6
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	6.2	0.3	0.9	0.4	-0.1	-1.2	-1.0	-2.5	-1.2	-0.8	-2.0	-0.3	-0.1
Medication: Simvastatin	1.0	1.4	3.3	1.8	0.5	0.7	0.3	-0.5	1.6	0.8	1.8	1.1	1.4	1.1	1.6
Neuroticism score	1.0	2.0	6.4	-0.7	0.4	0.2	1.3	2.1	-0.3	-1.7	-1.7	-2.2	-2.5	0.3	-0.2
Lung cancer (father)	1.0	1.2	3.9	1.1	-0.0	0.2	0.5	-2.0	0.2	1.1	1.3	1.1	1.7	-0.1	1.1
Hair/balding pattern: Pattern 4	1.0	2.4	4.9	-0.6	-1.6	-1.4	-1.9	-1.2	-1.6	-1.9	-0.6	-2.0	-1.1	-2.2	-1.4
Birth weight	1.0	2.2	4.2	-2.0	-1.4	-1.8	-1.6	-0.2	-1.8	-1.2	0.0	-2.0	-0.3	-1.3	-1.9
Number of children fathered	1.0	1.1	2.4	1.3	1.1	1.2	-0.5	-0.5	1.1	0.9	0.5	1.3	0.1	1.6	1.5
Emphysema/chronic bronchitis	1.0	1.2	3.0	0.4	1.3	0.8	1.7	-1.0	0.1	-0.4	-1.4	-0.2	-1.7	1.6	0.1
Migraine (self-reported)	1.0	1.3	2.7	1.6	1.2	1.2	0.5	0.3	0.6	1.4	1.3	1.6	1.1	1.0	0.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.3	-1.5	-0.7	-0.8	0.1	0.6	-1.2	-1.5	-0.8	-1.5	-0.9	-1.0	-1.4
Diabetes diagnosed by doctor	1.0	1.7	4.5	1.3	1.2	1.5	2.1	1.8	1.6	1.2	-0.3	0.2	0.9	0.9	1.2
Eye problems/disorders: Cataract	1.0	1.2	7.4	0.6	-0.2	-0.3	1.3	-2.7	0.9	-0.1	0.7	-0.4	-1.4	0.9	0.6
Neuroticism (Nagel 2018)	0.9	2.0	4.0	-1.6	0.0	-0.1	0.9	1.9	-1.6	-1.6	-2.0	-1.9	-1.9	-0.6	-0.7
Ovarian Cancer	0.9	1.1	3.7	1.5	1.1	1.2	0.8	-0.5	1.9	0.2	-1.2	-0.8	-1.0	0.9	0.4
Mean Putamen Volume	0.9	1.0	5.7	-1.7	-0.7	-0.3	-0.1	-1.0	-0.7	-0.5	-0.5	-0.4	0.7	-2.4	-0.5
Hand grip strength (left)	0.9	2.2	12.1	0.3	0.4	0.3	0.2	-1.9	-1.4	-3.5	-0.2	-1.6	-1.6	-1.6	-1.0
Number of treatments/medications taken	0.9	1.7	4.8	2.2	1.6	1.9	1.2	0.5	1.3	-0.4	1.1	-0.2	0.0	0.9	1.9
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.3	0.9	0.9	0.8	0.4	-0.1	0.7	1.7	-0.5	1.6	0.1	1.6	1.8
Hearing difficulty/problems: Yes	0.9	1.3	5.8	0.7	1.1	0.6	1.1	1.0	-1.3	-2.4	-0.8	-0.4	-1.8	-0.2	0.0
Average weekly fortified wine intake	0.9	1.0	3.8	-0.5	-0.7	-0.6	-2.0	0.4	-0.0	1.5	1.5	-0.2	1.7	-0.2	-0.1
Maternal smoking around birth	0.9	1.4	4.4	-0.1	-0.1	0.0	0.6	0.7	1.6	1.5	0.9	1.0	0.5	2.1	2.0
Relative age voice broke	0.9	1.4	7.6	-1.5	-0.8	-1.0	-1.6	-0.0	0.1	-0.4	-2.8	0.2	-1.4	0.2	-0.5
Past tobacco smoking	0.9	1.7	6.2	-1.1	-1.5	-1.6	-2.5	-2.2	-1.1	-0.4	-0.3	-0.3	-0.3	-0.6	-1.2
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.2	0.0	1.0	0.8	1.1	-0.9	-0.2	-1.7	-1.4	-1.2	-1.8	0.4	-0.4
Worrier / anxious feelings	0.9	1.7	4.9	-2.2	-1.5	-1.4	-0.5	0.5	-1.2	-0.7	-0.3	-1.8	-0.1	-1.6	-1.8
Had major operations	0.9	1.1	3.9	-0.6	-0.9	-1.1	-1.1	1.0	-0.4	0.0	-1.5	-0.7	-1.2	-0.1	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	4.5	-0.3	-0.2	-0.6	-0.3	-1.1	-0.1	-2.1	-0.5	-1.5	-1.9	0.5	-0.6
Illnesses of siblings: Diabetes	0.9	1.1	4.1	-0.1	0.8	0.7	0.3	-0.9	-0.0	-2.0	-0.8	-1.7	-1.7	-0.5	-0.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	4.4	0.3	-0.2	-0.3	0.5	0.3	-1.2	-2.1	-0.1	-1.8	-0.7	-1.8	-1.2
Supplements: Calcium	0.9	1.0	2.0	-0.9	-0.8	-1.2	0.6	-0.4	-1.3	-1.4	1.0	-1.1	-0.8	-0.3	-1.4
Smoking Status	0.8	2.0	3.5	1.3	1.5	1.7	1.8	0.7	1.6	1.6	0.3	1.3	1.2	1.2	1.9
Allergy or Eczema	0.8	2.0	6.4	-0.5	-0.5	-0.8	0.3	-0.5	-1.0	-2.2	-1.8	-2.1	-2.5	-0.5	-1.5
Ever had hysterectomy (womb removed)	0.8	0.9	2.8	-0.0	-1.3	-1.1	-0.2	-0.7	-0.2	0.4	1.7	-1.3	1.3	-1.1	-0.5
Forced vital capacity (FVC)	0.8	3.1	10.1	-1.2	-1.3	-1.5	-0.1	-0.8	-2.1	-3.2	-0.9	-2.1	-2.1	-1.7	-2.1
Exposure to tobacco smoke at home	0.8	0.9	2.6	-0.9	-0.9	-0.9	0.7	0.1	0.6	1.6	-1.0	1.6	0.8	0.5	0.6
Loud music exposure frequency	0.8	0.9	2.6	1.6	1.4	1.6	0.4	0.8	0.4	1.0	-0.8	0.6	0.2	0.4	0.5
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.4	-0.5	0.7	0.6	0.4	1.6	-0.5	-1.0	-1.1	-1.3	-1.5	-0.2	1.1
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.6	0.6	0.6	0.7	-0.3	-0.3	1.5	-0.0	-0.8	-1.0	-1.6	1.3	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.9	-1.1	-1.2	-1.0	-0.1	1.4	-1.2	-0.6	0.7	-0.4	0.6	-1.7	-0.8
Number of full sisters	0.8	0.9	3.9	-0.1	-0.3	0.1	-0.1	1.2	-0.5	1.5	-0.0	2.0	1.8	-0.3	0.5
Mood swings	0.8	1.4	4.8	-0.8	-0.3	-0.5	0.5	1.1	-1.0	-1.7	-2.1	-1.2	-2.2	-0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	4.1	-0.2	-0.1	-0.3	1.0	0.0	-0.8	-1.6	-2.0	-0.5	-1.7	-0.3	-0.4
Osteoporosis (self-reported)	0.8	0.9	3.6	0.4	0.4	0.2	0.7	-0.5	1.3	-1.3	-1.1	-0.0	-1.9	1.4	0.4
Smoking status: Current	0.8	1.2	5.4	-0.1	-0.9	-0.7	-1.0	-1.0	0.5	2.3	1.2	0.6	1.6	0.5	0.9
Commuting to job workplace: Public transport	0.8	0.9	2.5	0.6	0.9	1.1	-0.1	-1.0	1.6	1.1	0.1	1.5	0.5	0.8	0.7
Pain experienced in last month	0.8	1.3	5.5	0.2	1.4	1.5	2.3	-0.8	1.8	0.1	0.7	0.0	0.4	0.5	0.7
Intelligence (Savage-Jansen 2018)	0.7	2.0	6.3	-0.8	-1.4	-1.4	-2.5	-1.4	-1.3	1.1	1.1	0.6	1.9	-1.2	-1.3
Breast Cancer	0.7	1.7	5.4	1.8	1.0	0.8	2.3	1.0	0.8	-0.5	-0.2	-1.5	-1.9	1.5	0.5
Blood Red Count	0.7	6.6	25.9	-0.8	3.1	3.5	1.6	1.4	2.7	-1.9	-5.1	0.4	-3.0	0.9	2.3
Angina	0.7	1.0	3.6	0.8	-0.2	-0.0	-1.0	1.9	1.2	1.7	0.3	0.5	0.6	1.1	0.6
Medication for hormone replacement therapy	0.7	0.8	2.3	1.5	1.0	1.1	1.5	-0.9	0.3	0.8	-0.5	0.7	0.2	0.8	0.8
Vitamin and mineral supplements	0.7	1.0	3.2	-0.9	-1.6	-1.2	-1.0	-1.0	0.3	1.8	0.1	0.8	0.8	0.5	-0.2
Medication: Co-codamol	0.7	0.8	3.6	1.9	0.0	0.3	-0.8	-1.1	0.2	0.2	1.6	-0.1	0.9	-0.5	0.2
Hand grip strength (right)	0.7	1.8	8.2	-0.0	-0.3	-0.5	-0.1	-1.7	-1.6	-2.9	0.5	-1.3	-1.0	-1.8	-1.2
Age when periods started (menarche)	0.7	1.6	7.2	-0.2	0.2	0.6	-1.2	-0.7	0.6	2.5	0.8	1.1	2.7	0.0	0.7
Serious illness, injury or assault to yourself	0.7	0.9	3.0	1.4	0.5	0.4	-0.4	-1.2	0.5	0.7	0.2	1.7	0.6	0.5	1.5
Sitting height	0.7	4.9	11.4	-2.8	-2.5	-2.8	-1.4	-2.2	-3.3	-1.0	1.6	-0.6	0.4	-1.8	-3.4
Hearing difficulty/problems with background noise	0.7	1.1	5.3	0.5	0.9	0.6	1.9	2.3	0.3	-0.3	-0.4	0.4	-0.4	1.1	0.9
Diabetes (self-reported)	0.7	1.1	4.4	1.2	1.1	1.3	2.1	1.6	0.7	0.7	-0.1	-0.1	0.6	0.5	0.7
Father’s age at death	0.7	1.0	2.8	0.0	-0.4	-0.4	-0.7	-0.1	-1.2	0.1	1.7	-0.8	1.5	-1.6	-1.1
Breastfed as a baby	0.7	0.9	3.2	-0.6	-1.6	-1.5	-1.8	-0.2	-0.6	-0.0	0.9	-0.1	0.5	-0.8	0.1
Peak expiratory flow (PEF)	0.7	1.6	4.1	-1.1	-1.5	-1.5	-0.8	0.5	-2.0	-1.4	-0.4	-1.0	-1.0	-1.6	-1.3
Gout (self-reported)	0.7	1.0	3.9	-0.1	0.4	0.3	0.3	0.0	0.8	-1.9	-1.3	-1.1	-2.0	0.2	-0.6
Medication: Amlodipine	0.7	1.0	3.0	-0.9	-0.9	-0.7	-0.9	0.7	-0.6	-0.8	1.0	-1.4	1.0	-1.7	-0.8
Neck or shoulder pain in last month	0.7	1.0	4.4	-0.5	-0.9	-1.0	-0.3	1.2	-2.1	-0.8	-1.2	-0.1	-1.1	-0.2	-0.5
Angina (self-reported)	0.7	0.9	2.9	0.5	-0.6	-0.3	-1.1	1.7	0.8	1.6	0.7	0.6	0.8	0.8	0.4
Age at last live birth	0.7	1.0	2.5	0.6	0.8	0.8	0.0	-1.3	1.6	0.4	-1.1	0.5	-1.0	1.1	1.4
Family relationship satisfaction	0.7	0.9	3.0	0.7	0.8	0.6	0.1	-0.2	1.0	-0.0	-0.5	-0.5	-1.6	1.7	1.3
Supplements: Vitamin C	0.7	0.8	5.0	0.2	-0.4	-0.9	-0.2	-0.1	-0.6	0.0	2.2	-0.4	0.7	-0.2	-1.5
Average weekly beer plus cider intake	0.7	1.0	5.9	1.0	0.3	0.6	-0.4	-0.1	0.0	0.4	2.4	-0.5	1.4	0.4	1.4
Fractured/broken bones in last 5 years	0.7	0.9	4.9	0.6	0.4	0.3	0.1	0.7	0.6	1.2	0.7	2.2	0.9	1.1	0.8
Diastolic blood pressure, automated reading	0.7	2.1	6.1	0.5	2.2	2.1	1.1	-0.7	0.4	-1.4	-1.4	-1.6	-2.5	0.9	0.9
Unable to work because of sickness or disability	0.7	0.9	2.6	0.8	0.1	0.5	-1.0	-0.4	-0.1	1.6	1.3	0.3	1.6	-0.3	1.1
Pack years of smoking	0.7	1.0	5.3	-0.4	-1.1	-0.8	-1.0	-2.3	0.5	1.3	-1.1	0.3	0.6	-0.4	0.0
Reaction Time	0.6	1.1	3.6	-0.5	0.2	0.0	0.9	1.5	0.6	0.5	-1.6	1.9	-0.9	1.4	0.7
Prostate Cancer	0.6	0.9	5.4	-0.6	-0.5	-0.3	-1.1	2.3	0.5	0.9	1.0	-0.4	0.6	-0.3	0.9
Sensitivity / hurt feelings	0.6	1.1	3.6	0.3	1.1	0.9	0.8	-0.2	0.1	-0.0	-1.9	0.1	-1.9	1.4	1.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.6	0.4	0.3	0.3	1.6	1.2	0.1	1.6	0.6	0.6	0.9	0.7	0.4
Systolic blood pressure, automated reading	0.6	1.6	3.8	1.2	2.0	1.9	1.5	0.6	0.5	-1.1	-0.5	-1.6	-1.7	0.8	0.6
Diabetes (father)	0.6	0.8	4.7	0.9	0.3	0.3	-0.0	-0.7	-0.0	0.8	2.2	0.5	1.2	0.9	-0.0
Diabetes (mother)	0.6	0.7	3.2	-0.7	0.5	0.8	0.6	0.6	0.2	0.3	-1.7	1.8	0.0	0.2	0.7
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.8	-1.3	-1.1	-1.2	-0.2	-0.2	-0.4	-0.4	-0.8	-1.2	-0.9	0.0	-0.8
Medication: Atenolol	0.6	0.7	2.7	0.6	-0.2	-0.0	-0.0	1.6	-0.0	0.7	1.0	1.1	1.4	0.4	0.7
Chronic bronchitis/emphysema (father)	0.6	0.6	1.8	0.2	1.0	1.3	0.3	1.0	-0.1	0.5	1.2	0.6	1.3	0.2	0.3
Financial difficulties in last 2 years	0.6	0.9	1.7	0.9	1.1	1.2	1.0	-0.2	1.1	0.6	-1.0	-0.1	-0.6	1.3	1.1
Medication: Ramipril	0.6	0.8	3.1	0.9	0.5	0.8	-0.0	-0.2	0.3	-0.2	1.8	-0.3	1.5	-0.5	1.2
Mouth/teeth dental problems: Dentures	0.6	1.0	4.0	0.1	-2.0	-1.8	-0.7	1.7	-0.1	0.3	0.2	-0.6	0.4	-0.1	-0.5
Blood clot in the leg (DVT)	0.6	0.7	2.7	0.6	1.2	1.1	-0.1	-0.2	0.0	-0.8	-1.2	-0.8	-1.7	0.1	-0.1
Medication: Paracetamol	0.6	1.1	4.5	-0.8	-0.9	-1.0	-1.9	-1.1	-2.1	-0.0	0.3	-0.0	0.3	-0.8	-0.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.2	0.5	0.1	-0.0	0.6	-0.3	-1.1	1.5	0.6	1.5	1.2	0.4	-0.1
Ever had bowel cancer screening	0.6	0.7	2.2	0.7	-0.8	-0.6	0.3	0.8	0.9	0.9	1.5	0.1	1.4	0.5	-0.3
Ever depressed for a whole week	0.6	0.8	2.2	-0.3	0.2	-0.2	-0.3	-0.5	-1.1	-1.4	-0.9	-1.3	-1.5	-0.3	-1.0
Heel T-Score	0.5	3.8	12.5	1.0	-0.5	0.3	-1.6	-1.6	-1.9	-0.7	3.5	-0.9	3.0	-3.5	-0.6
Waist Hip Ratio (WHR)	0.5	2.3	10.6	-0.4	-0.4	-0.2	1.1	-1.6	-0.9	-2.1	0.0	-3.2	-0.7	-2.1	-1.8
Neuroticism	0.5	1.3	6.2	-1.1	-0.2	-0.3	-0.1	1.4	-0.6	-1.0	-1.3	-2.5	-1.5	-0.4	-0.3
Average weekly spirits intake	0.5	0.6	1.7	-1.1	-0.6	-0.3	-0.0	0.3	-0.3	0.3	-1.3	0.5	0.3	-1.3	-1.3
Relative age of first facial hair	0.5	1.1	4.3	-0.7	-0.3	-0.4	0.0	-1.1	0.0	-1.0	-2.1	-1.2	-1.5	-0.3	-1.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.5	-0.8	-0.4	-0.4	-0.3	-0.2	-1.0	1.2	1.2	0.8	1.2	-0.7	-0.1
Severe depression (siblings)	0.5	0.5	3.0	-0.4	-0.2	0.2	-0.2	1.7	-1.0	-0.1	-0.5	-0.5	0.2	-1.1	-0.8
Pack years adult smoking proportion	0.5	0.8	4.2	-0.4	-1.0	-0.7	-1.1	-2.0	0.5	1.1	-1.0	0.4	0.4	-0.2	0.3
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.5	-1.2	-1.0	-0.7	-0.2	-1.2	-0.1	0.4	0.6	-0.5	0.7	-0.7	0.5
Multivitamins +/- minerals	0.5	0.7	2.6	0.3	0.5	0.4	0.3	0.4	-0.7	-1.6	-0.9	-0.9	-0.9	-1.3	0.2
Impedance of leg (left)	0.5	2.5	9.7	-3.1	-2.0	-1.8	-1.4	0.8	-1.3	-0.7	0.7	-0.8	0.4	-2.0	-1.7
Illnesses of siblings	0.5	0.7	3.3	-0.7	-0.3	-0.5	-0.5	-0.1	-1.8	0.4	1.1	1.3	0.7	-0.2	-0.3
Noisy workplace	0.5	0.7	2.9	0.7	-0.0	0.2	1.0	1.7	-0.3	-1.2	0.0	-1.2	-0.4	-0.2	-0.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.4	-0.6	-1.0	-1.1	-0.5	-1.2	-0.9	-0.1	0.3	-0.1	0.4	-0.4	-1.1
Pulse wave reflection index	0.5	0.6	2.7	-0.3	0.5	0.4	0.8	-0.5	-1.0	-0.8	-1.6	0.0	-0.7	-0.7	-0.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	5.1	0.2	-0.7	-0.4	-0.7	-0.3	-0.4	0.5	2.2	-0.5	1.5	-1.2	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.4	0.0	-0.2	-0.4	1.1	1.5	-0.3	-0.1	1.5	-1.0	0.3	0.4	-0.3
Medication: Ibuprofen	0.5	0.6	1.9	1.0	1.2	1.4	-0.2	-1.2	-0.0	0.4	0.1	0.5	0.6	-0.3	0.5
Mean time to correctly identify matches	0.5	0.9	2.6	-0.3	-0.2	-0.3	0.4	0.5	1.1	1.0	-1.6	1.4	-0.4	1.6	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.6	-0.4	0.4	0.6	0.9	1.9	0.2	-0.9	-0.1	0.0	0.4	-0.1	0.7
Knee pain experienced in last month	0.5	0.8	3.8	0.4	-1.3	-1.2	-2.0	0.2	-0.5	-0.3	-0.2	-1.1	-0.6	-0.3	-0.3
Commuting to job workplace: Walk	0.5	0.5	2.0	-0.1	0.5	0.4	-1.3	-1.4	-0.7	-0.7	-0.4	-0.6	-0.6	-0.4	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	4.0	-0.1	1.0	1.1	0.8	-0.7	0.3	-0.6	-2.0	-0.5	-0.9	-0.3	0.3
Back pain experienced in last month	0.5	0.7	1.5	1.2	0.7	0.8	-0.4	1.1	0.9	-0.5	0.6	-0.7	-0.5	1.1	0.8
Breast cancer (self-reported)	0.5	0.6	1.9	-0.4	-0.5	-0.6	-0.9	0.9	-0.1	-1.4	-0.5	-0.7	-1.1	-0.4	-0.9
Number of self-reported non-cancer illnesses	0.5	0.8	2.7	0.6	1.1	1.0	0.7	1.6	0.8	-0.5	-0.4	-0.3	-1.2	1.0	0.9
Guilty feelings	0.5	0.7	6.6	-0.7	-0.4	-0.4	0.2	2.6	-0.1	-0.4	-0.6	-0.1	-0.3	0.3	0.4
Hearing aid user	0.5	0.5	2.1	0.9	-0.5	-0.3	-0.3	1.0	0.5	0.9	1.4	-0.0	1.1	0.4	-0.1
Medication: Paracetamol	0.5	0.8	3.0	-0.0	-0.2	-0.3	-1.3	-1.7	-1.5	0.5	0.7	0.8	0.7	-0.3	0.6
Illnesses of father: High blood pressure	0.5	0.6	4.6	-0.2	0.4	0.4	-0.5	-0.6	0.4	-0.5	-2.1	0.1	-0.7	0.2	0.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.0	-0.9	-0.8	-1.0	-0.1	-1.1	-0.3	0.0	-0.0	-0.8	-0.1	-0.3	-1.7
Cholesterol lowering medication	0.5	0.7	2.2	0.8	0.5	0.7	0.4	0.0	0.9	1.4	0.4	0.7	1.2	0.6	1.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.4	0.4	1.1	1.0	0.0	-0.2	-0.2	-0.9	-1.0	-0.6	-1.6	-0.0	-0.4
Depressed Affect (Nagel 2018)	0.4	0.9	3.3	-0.2	0.4	0.4	0.7	1.1	-0.7	-0.9	-1.7	-0.9	-1.8	0.2	0.4
HbA1C	0.4	0.5	1.8	-0.4	-1.3	-1.1	-0.7	-0.1	-0.6	0.4	-0.2	-0.3	0.2	-0.5	-1.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	5.3	0.6	0.8	1.0	2.3	1.2	0.3	-0.1	-0.2	-0.2	0.4	0.3	0.2
Hair Pigment	0.4	10.2	24.6	4.1	4.8	5.0	3.5	0.4	3.2	1.3	1.1	2.2	0.7	2.5	4.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.9	-0.2	0.6	0.7	0.9	0.4	1.1	0.3	-1.4	0.0	0.3	-0.1	0.1
Impedance of leg (right)	0.4	2.1	9.8	-3.1	-1.8	-1.6	-1.6	0.4	-1.1	-0.5	0.0	-0.6	-0.0	-1.9	-1.4
Fed-up feelings	0.4	0.8	2.0	1.4	1.1	1.0	0.9	1.1	-0.0	-0.6	0.2	0.1	-1.0	1.3	0.3
Qualifications: CSEs or equivalent	0.4	0.6	2.7	0.9	0.5	0.8	0.8	0.0	1.0	-0.4	0.6	0.3	0.4	0.3	1.6
Number of incorrect matches in round	0.4	0.6	2.2	-1.1	0.1	-0.0	1.3	1.5	-0.0	-0.2	-1.0	-0.4	-0.8	0.3	-0.2
Heart attack	0.4	0.5	3.2	0.7	0.4	0.5	0.4	0.7	0.4	1.8	-0.3	0.7	0.8	0.5	0.5
Number of live births	0.4	0.6	2.1	0.2	0.4	0.5	1.0	-0.4	-0.0	-1.4	0.6	-0.9	-0.9	-0.7	0.7
Medication: Cholesterol lowering	0.4	0.7	2.2	1.2	-0.0	0.3	-0.7	-0.2	1.2	0.3	1.5	0.1	1.0	0.4	1.2
Prospective memory result	0.4	0.5	1.4	0.9	0.6	0.7	0.6	0.0	0.9	-0.1	1.2	0.5	0.3	1.0	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.7	0.5	0.4	0.4	-0.2	0.9	-1.6	-0.9	0.4	-1.4	-0.5	-0.7	-0.4
Glaucoma (self-reported)	0.4	0.5	2.6	0.6	-0.3	-0.2	-0.3	0.0	-0.9	0.2	1.6	-0.0	0.8	-0.7	-0.6
Age at first live birth	0.4	0.7	2.1	-1.1	-0.8	-0.9	-1.4	-0.8	1.1	1.1	-0.9	-0.2	-0.3	0.2	-0.4
Pulse wave peak to peak time	0.4	0.4	1.3	0.5	0.8	1.0	0.3	1.1	0.9	0.3	-0.1	0.1	-0.2	0.2	1.0
Qualifications: College or University degree	0.4	1.2	3.2	-1.0	-1.4	-1.2	-0.5	-1.5	-0.6	0.8	0.9	0.9	1.3	-1.8	-0.4
Medication: Omeprazole	0.4	0.5	1.6	-0.0	-0.9	-0.9	-0.6	-1.3	-0.6	-0.6	0.6	-0.1	0.4	-0.7	-0.6
Chest pain or discomfort	0.4	0.6	2.6	0.6	0.6	0.5	0.5	-0.2	1.0	0.9	0.4	-0.2	-0.2	1.6	1.4
Average weekly champagne plus white wine intake	0.4	0.6	2.0	0.2	-0.8	-0.7	-0.7	-1.4	0.0	0.3	1.0	0.9	0.9	-0.5	-0.8
Miserableness	0.4	0.7	2.2	-0.2	-0.4	-0.5	0.6	0.6	-0.8	-1.2	0.1	-1.5	-1.3	-0.2	-0.8
Mother’s age at death	0.4	0.5	1.9	-0.5	-0.7	-0.7	-1.4	-0.6	-0.8	-0.4	0.1	-0.6	0.1	-1.0	-0.2
Eye problems/disorders: Glaucoma	0.4	0.5	2.3	0.1	-0.5	-0.4	-0.3	-0.3	-0.9	0.4	1.5	-0.3	1.0	-0.8	-0.7
Medication: Blood pressure	0.4	0.8	3.2	0.6	0.9	1.2	0.8	1.3	0.6	0.3	-0.3	0.8	0.2	0.8	1.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.6	-0.3	-0.2	-0.3	0.4	0.3	-0.2	-1.1	-1.6	-0.6	-1.3	-0.1	-0.1
Age started oral contraceptive pill	0.4	0.5	2.0	0.4	-0.2	-0.1	-0.4	-0.7	0.5	1.0	1.4	0.4	1.3	0.5	-0.2
Commuting to job workplace: Cycle	0.4	0.4	1.4	-0.4	-0.6	-0.5	-0.4	-1.2	0.1	0.9	0.8	0.8	0.8	0.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.5	0.6	0.1	0.3	0.3	0.5	0.5	1.9	-0.2	0.7	0.9	0.5	0.4
Age at First Birth	0.3	0.4	2.1	-0.7	-0.5	-0.6	-1.1	0.2	0.3	-0.4	-0.2	0.0	-1.4	0.4	-0.3
Neuroticism (2016)	0.3	0.4	1.4	-1.2	-0.2	-0.1	0.1	0.6	-0.7	-0.6	-0.3	-0.7	0.2	-1.1	-0.0
Rheumatoid Arthritis	0.3	0.5	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.4	0.0	-1.6	0.9	0.2
Supplements: Zinc	0.3	0.3	1.5	0.3	-0.7	-0.6	-1.2	-0.5	0.4	-0.1	0.4	-0.9	0.1	-0.2	-0.4
Leg fat-free mass (left)	0.3	1.6	4.9	2.2	2.2	1.9	1.1	-0.3	0.1	0.3	-0.6	0.6	-0.5	1.5	0.7
Medication: Levothyroxine sodium	0.3	0.4	1.3	1.1	0.4	0.4	-0.6	-1.0	0.3	-0.4	0.9	-0.6	0.1	-0.7	0.5
Leg predicted mass (left)	0.3	1.5	4.8	2.2	2.2	1.9	1.0	-0.2	0.1	0.3	-0.6	0.6	-0.5	1.5	0.7
Alcohol usually taken with meals	0.3	0.4	2.0	-0.5	-0.2	-0.5	-0.4	-1.4	0.0	1.1	-0.5	0.8	0.4	0.3	-0.5
Had menopause	0.3	0.4	2.0	0.4	0.7	0.5	1.4	0.5	0.5	-0.1	-0.4	-0.3	-0.7	0.6	0.5
Had other major operations	0.3	0.3	0.9	0.9	0.3	0.6	-0.2	-0.3	0.5	0.2	-0.9	-0.7	-0.9	0.2	0.3
Fluid intelligence score	0.3	0.6	1.8	-0.1	-0.6	-0.7	-0.6	-0.7	-0.3	0.6	1.4	-0.5	0.7	-0.8	-1.1
Hip circumference	0.3	1.2	3.5	0.9	1.2	1.3	-0.6	0.3	0.1	1.1	-1.9	1.7	0.0	0.7	1.3
Alcohol intake versus 10 years previously	0.3	0.5	1.8	-0.3	-0.1	-0.2	0.9	0.9	-0.3	-0.7	-0.3	-1.1	-0.5	0.3	-1.3
Falls in the last year	0.3	0.5	2.7	-0.7	-0.4	-0.4	0.6	0.1	0.0	-0.3	-1.6	-0.9	-0.6	-0.7	-0.4
Pulse rate	0.3	0.4	2.2	0.7	0.3	0.1	-0.3	1.5	-0.1	-0.9	0.1	-0.6	-0.7	-0.2	-0.7
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.9	-1.3	-0.6	-1.0	-0.8	-0.9	-0.1	-0.0	-0.4	-0.5	-1.4	0.3	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.0	0.0	0.7	0.5	0.6	-0.9	-0.8	0.2	-1.0	0.4	-0.3	0.1	0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.3	-0.9	0.3	0.0	0.7	0.9	-1.1	0.1	-1.5	0.5	-0.6	-0.1	-0.3
Exposure to tobacco smoke outside home	0.3	0.4	1.8	-0.9	-0.5	-0.4	-0.2	0.3	-0.3	0.7	-1.3	0.4	0.1	-0.4	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	0.9	0.8	0.6	0.5	1.0	-0.2	0.1	0.2	-0.4	-0.3	0.5	0.7
Heart disease (mother)	0.3	0.4	1.0	-0.5	-0.7	-0.6	0.8	0.4	-0.5	-0.5	1.0	-0.9	0.2	-0.6	-0.1
Comparative height size at age 10	0.3	1.8	6.3	1.1	1.1	0.6	2.1	2.5	-0.4	0.7	2.0	0.7	0.1	1.6	-0.6
Leg fat-free mass (right)	0.3	1.4	5.2	2.3	2.0	1.8	1.2	-0.2	0.1	0.3	-0.1	0.6	-0.2	1.5	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.0	0.1	0.4	0.5	0.6	-0.5	0.4	-0.0	-0.7	-0.4	-0.9	0.5	1.0
Leg predicted mass (right)	0.3	1.5	5.4	2.3	2.1	1.8	1.3	-0.1	0.1	0.3	-0.1	0.7	-0.2	1.5	0.5
Ever taken oral contraceptive pill	0.3	0.4	0.8	-0.8	-0.5	-0.5	-0.1	0.5	-0.9	0.8	0.9	0.2	0.8	-0.4	-0.1
High cholesterol (Self-reported)	0.3	0.4	1.6	0.3	-0.4	-0.0	-0.6	-0.9	-0.0	0.5	1.0	0.2	1.3	-0.5	0.9
Medication: Atorvastatin	0.3	0.4	1.0	-0.3	-0.7	-0.6	-0.7	1.0	-0.4	0.6	0.5	-0.1	0.7	-0.6	-0.3
Ever smoked	0.3	0.4	2.1	0.1	-0.1	0.0	1.0	1.5	0.3	0.9	0.5	0.3	0.9	-0.0	0.4
Risk taking	0.3	0.5	1.7	-0.8	-1.2	-1.3	-0.8	0.5	-0.6	0.2	0.4	0.2	0.6	-0.2	-0.5
Myopia	0.3	0.4	3.8	-0.2	-0.7	-0.6	-1.9	-0.3	0.0	0.0	0.2	-0.1	0.7	-0.2	0.2
Impedance of whole body	0.3	1.4	5.9	-2.4	-1.2	-1.5	-0.5	1.0	-0.7	-0.6	-0.2	-0.6	-0.9	-0.5	-1.9
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.8	-0.6	-0.6	-0.8	-0.8	-0.4	-0.0	0.7	1.4	0.5	0.7	0.1	-0.6
BMI	0.2	0.9	3.7	1.4	0.8	1.2	-0.9	1.9	0.1	0.7	-1.0	0.4	0.4	-0.0	1.0
Systolic Blood Pressure	0.2	0.9	3.2	0.7	1.5	1.8	0.9	0.3	0.8	-0.4	0.2	-1.2	-0.8	0.6	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.6	0.5	-0.4	-0.3	0.8	0.8	-0.1	-0.4	-0.5	-0.6	-0.8	-0.0	-0.4
High blood pressure	0.2	0.5	1.8	0.6	0.3	0.5	0.5	1.3	0.2	-0.9	1.1	-1.0	-0.1	-0.0	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.8	0.2	-0.0	-0.3	0.7	0.1	-0.8	0.3	-0.4	-0.9	-0.5	0.4	-0.9
Impedance of arm (right)	0.2	0.7	2.3	-0.4	0.4	-0.0	0.8	1.2	0.5	-0.1	-0.9	0.3	-1.5	1.4	-0.9
Arm fat percentage (right)	0.2	0.9	4.4	0.9	1.3	1.4	0.1	0.6	0.1	0.2	-2.1	0.4	-0.8	0.8	0.6
Happiness	0.2	0.2	0.7	-0.1	0.4	0.5	0.8	0.4	-0.4	-0.7	0.2	-0.4	-0.7	-0.2	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.0	0.2	0.9	0.8	-0.1	-1.0	-0.7	-0.6	-0.3	-0.1	-0.4	-0.2	-0.5
Medication: Lansoprazole	0.2	0.2	1.2	0.3	-0.2	-0.2	-0.1	-0.1	-0.2	-0.8	1.1	-0.6	-0.1	-0.4	-0.1
Illnesses of mother	0.2	0.2	0.8	0.4	0.9	0.5	0.6	0.0	-0.3	-0.4	-0.0	-0.2	-0.4	0.3	-0.7
Impedance of arm (left)	0.2	0.7	2.9	-1.0	-0.2	-0.7	0.1	0.7	0.0	-0.1	-0.9	0.4	-1.3	0.9	-1.7
Arm fat mass (right)	0.2	0.7	2.3	0.9	1.4	1.5	0.3	0.6	-0.2	0.0	-1.5	0.3	-0.5	0.5	0.7
Birth weight of first child	0.2	0.3	1.3	-0.7	-0.7	-0.7	0.3	-0.0	0.3	-0.3	0.6	-1.1	-0.3	0.5	0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	2.0	-0.3	-0.1	0.2	0.3	-0.4	0.1	0.4	-1.4	-0.1	-0.4	-0.1	0.3
Headache pain in last month	0.2	0.4	1.9	-0.5	-0.1	-0.4	-0.2	-0.7	-0.4	-0.2	-1.0	0.8	-1.4	0.7	0.2
High blood pressure (siblings)	0.2	0.3	1.2	-0.5	-1.1	-0.7	-0.6	-0.2	0.5	-0.3	0.3	-0.7	0.5	-0.8	-0.1
Medication: Blood pressure	0.2	0.4	2.4	0.5	-0.3	-0.3	-0.6	-0.5	0.2	-0.0	1.6	-0.6	0.7	0.0	-0.6
Medication: Aspirin	0.2	0.3	1.9	-0.4	0.0	0.1	0.4	0.9	1.4	0.1	0.4	0.1	0.4	0.5	0.1
Whole body fat-free mass	0.2	0.9	3.1	1.8	1.7	1.7	0.6	-0.4	-0.1	0.5	0.3	0.5	0.4	0.8	0.7
Arm fat percentage (left)	0.2	0.9	5.9	0.6	1.1	1.1	-0.1	0.5	-0.2	0.0	-2.4	0.4	-0.9	0.5	0.3
Average weekly red wine intake	0.2	0.3	1.0	-0.0	-0.9	-1.0	0.2	-0.9	-0.3	0.1	0.4	-0.8	-0.3	-0.3	-0.3
Medication: Aspirin	0.2	0.3	1.2	-0.3	0.1	0.2	0.4	1.0	1.1	0.2	0.4	0.2	0.2	0.6	0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	0.6	-0.1	-0.5	-0.5	-0.6	-0.6	-0.0	-0.6	0.1	-0.3	-0.8	0.1	-0.2
Whole body water mass	0.2	0.9	2.9	1.7	1.7	1.7	0.6	-0.3	-0.2	0.4	0.4	0.5	0.4	0.7	0.6
Arm fat mass (left)	0.2	0.7	3.0	0.6	1.2	1.3	0.1	0.6	-0.6	-0.2	-1.7	0.2	-0.6	0.2	0.4
Wears glasses or contact lenses	0.2	0.2	0.6	-0.6	0.3	0.0	0.2	0.8	-0.1	-0.4	-0.4	-0.4	-0.6	0.5	-0.8
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.7	-0.9	-0.5	-0.7	-0.4	-1.6	-0.5	0.3	-1.2	0.5	-0.3	-0.5	-0.6
Depression (Nagel 2018)	0.1	0.2	0.8	-0.2	-0.1	0.0	-0.3	-0.8	-0.2	0.3	-0.9	0.6	-0.5	-0.0	0.4
Height	0.1	1.1	4.4	-0.9	0.7	-0.1	0.2	-2.1	-1.5	-1.0	0.1	0.5	-1.0	0.6	-1.7
Cardiovascular Disease	0.1	0.3	1.6	0.8	0.4	0.9	0.5	-0.5	0.4	-0.4	0.2	0.2	-0.0	0.1	1.3
Tanning	0.1	1.0	4.5	0.8	0.6	0.8	0.7	0.4	1.0	0.8	1.2	0.7	0.6	0.8	2.1
Trunk fat percentage	0.1	0.6	3.2	-0.3	0.2	0.2	-0.8	0.7	-1.0	-0.1	-1.8	-0.2	-0.6	-0.1	-0.9
Body mass index (BMI)	0.1	0.4	2.3	0.7	0.7	0.8	-0.5	0.5	-0.6	-0.1	-1.5	-0.2	-0.3	-0.1	0.6
Trunk fat mass	0.1	0.4	1.9	0.2	0.7	0.6	-0.5	0.3	-0.9	0.1	-1.4	0.0	-0.3	0.1	-0.5
Waist circumference	0.1	0.4	2.2	0.6	0.7	0.9	-0.1	0.2	-0.6	0.0	-1.5	-0.4	0.1	-0.6	0.0
Qualifications: None of the above	0.1	0.2	1.5	0.3	-0.1	0.0	-0.1	-0.6	0.1	1.2	0.2	-0.3	0.6	0.4	0.5
Mouth/teeth dental problems	0.1	0.2	0.9	-0.4	0.3	-0.1	-0.3	-0.5	-0.7	-0.2	0.8	1.0	0.0	0.0	-0.2
Weight	0.1	0.4	1.2	0.8	1.0	1.0	-0.1	0.5	-0.7	0.1	-1.1	0.1	-0.3	0.3	0.1
Trunk fat-free mass	0.1	0.8	2.1	1.4	1.4	1.4	0.4	-0.6	-0.1	0.7	0.6	0.7	0.9	0.3	0.8
Trunk predicted mass	0.1	0.8	2.3	1.4	1.4	1.5	0.4	-0.6	-0.1	0.7	0.7	0.7	1.0	0.4	0.9
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.8	0.1	0.4	0.1	-0.1	-0.2	0.1	-0.8	0.4	-0.3	-0.9	0.0	-0.4
Body fat percentage	0.1	0.5	3.8	-0.3	0.4	0.4	-0.7	0.7	-0.7	0.1	-1.9	-0.1	-0.5	-0.1	-0.4
Leg fat percentage (right)	0.1	0.5	4.0	-0.8	-0.0	0.1	-0.8	-0.2	-0.8	0.1	-2.0	-0.1	-0.3	-0.6	0.1
Arm fat-free mass (right)	0.1	0.4	1.2	0.7	1.1	1.1	0.2	-0.3	-0.8	-0.1	0.5	0.0	0.5	-0.3	0.2
Comparative body size at age 10	0.1	0.3	1.8	0.2	-0.0	-0.3	-1.3	-1.2	-0.5	0.2	0.0	0.1	0.1	0.0	-0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.5	0.0	-0.4	-0.3	0.4	0.7	0.6	0.7	-0.2	-0.3	0.4	-0.3	-0.2
Whole body fat mass	0.1	0.3	1.6	0.3	0.7	0.8	-0.3	0.5	-0.7	0.1	-1.2	-0.1	-0.2	0.1	-0.1
Leg fat mass (right)	0.1	0.3	2.1	-0.0	0.7	0.7	-0.1	0.3	-0.8	-0.2	-1.5	-0.3	-0.5	-0.1	0.2
Arm predicted mass (right)	0.1	0.4	1.2	0.7	1.1	1.1	0.1	-0.6	-0.7	0.2	0.5	0.1	0.7	-0.2	0.3
Pulse rate, automated reading	0.1	0.2	0.8	-0.4	0.2	0.4	-0.9	-0.2	-0.1	0.0	-0.2	-0.2	0.5	-0.7	-0.0
Hypertension (Self-reported)	0.1	0.4	1.9	0.6	0.2	0.4	0.6	0.9	0.1	-0.4	1.4	-0.7	0.3	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.1	-1.0	0.4	0.3	0.1	-0.4	-0.6	-0.2	-0.9	0.2	-0.4	-0.4	-0.1
Qualifications: nursing, teaching	0.1	0.2	0.8	-0.1	-0.5	-0.6	-0.8	-0.9	-0.2	0.7	-0.0	0.3	-0.1	0.3	0.3
Medication: Lisinopril	0.1	0.2	1.2	-0.0	-0.1	0.1	-0.2	-0.8	-0.0	0.2	-0.0	-1.1	-0.0	-0.5	-0.1
Basal metabolic rate	0.1	0.8	2.8	1.5	1.7	1.6	0.5	-0.1	-0.3	0.4	-0.0	0.5	0.2	0.7	0.6
Leg fat percentage (left)	0.1	0.3	2.2	-0.5	-0.1	0.1	-0.8	0.1	-0.8	-0.0	-1.5	-0.3	0.0	-0.7	-0.1
Arm fat-free mass (left)	0.1	0.6	2.2	1.1	1.3	1.5	0.4	0.1	-0.6	-0.2	0.8	-0.3	0.5	-0.2	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.8	0.5	-0.1	-0.2	0.1	-0.6	-0.2	-0.9	0.2	0.3	-0.3	0.2	0.1
Leg fat mass (left)	0.1	0.3	1.4	0.1	0.6	0.7	-0.1	0.4	-0.8	-0.2	-1.2	-0.4	-0.2	-0.3	0.1
Arm predicted mass (left)	0.1	0.6	2.3	1.1	1.4	1.5	0.5	0.2	-0.5	-0.4	0.6	-0.5	0.2	-0.1	0.7
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Standing height	0.0	0.4	1.4	0.2	0.8	0.5	0.6	0.0	-0.6	-0.0	0.9	0.2	-0.2	0.6	-1.2

Hub : Genes

CNN2

Models

Trait associations