TWAS hub - CNOT8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0210	1.8e-04	0.036	0.043	0.042	0.041	0.048	2.8e-05	5.2e-06	6.4e-06	7.7e-06	1.5e-06
2	GTEx	Adipose Subcutaneous	0.2060	0.0430	8.0e-10	0.220	NA	0.224	NA	0.225	7.5e-18	NA	3.0e-18	NA	3.0e-18
3	GTEx	Adipose Visceral Omentum	0.1680	0.0600	9.4e-04	0.149	NA	0.106	NA	0.116	3.9e-08	NA	3.9e-06	NA	1.3e-06
4	GTEx	Artery Aorta	0.1550	0.0560	1.6e-03	0.100	NA	0.037	NA	0.073	3.9e-06	NA	4.0e-03	NA	7.6e-05
5	GTEx	Artery Tibial	0.2679	0.0505	9.1e-12	0.197	NA	0.178	NA	0.204	2.5e-15	NA	6.9e-14	NA	7.2e-16
6	GTEx	Breast Mammary Tissue	0.2320	0.0640	1.8e-05	0.062	NA	0.049	NA	0.085	4.1e-04	NA	1.6e-03	NA	4.0e-05
7	GTEx	Esophagus Muscularis	0.1660	0.0580	1.1e-03	0.074	NA	0.030	NA	0.045	2.9e-05	NA	6.1e-03	NA	1.0e-03
8	GTEx	Lung	0.3012	0.0504	3.9e-12	0.230	NA	0.197	NA	0.219	1.4e-17	NA	5.4e-15	NA	1.1e-16
9	GTEx	Muscle Skeletal	0.1002	0.0393	2.7e-04	0.019	NA	0.052	NA	0.047	5.5e-03	NA	7.5e-06	NA	2.1e-05
10	GTEx	Nerve Tibial	0.1978	0.0488	2.0e-06	0.200	NA	0.178	NA	0.196	3.8e-14	NA	1.2e-12	NA	6.5e-14
11	GTEx	Skin Sun Exposed Lower leg	0.1770	0.0440	4.3e-07	0.171	NA	0.152	NA	0.165	4.3e-14	NA	1.3e-12	NA	1.3e-13
12	GTEx	Testis	0.1530	0.0530	9.2e-04	0.090	NA	0.112	NA	0.118	8.6e-05	NA	1.2e-05	NA	6.5e-06
13	GTEx	Thyroid	0.2220	0.0500	2.8e-07	0.179	NA	0.157	NA	0.178	1.1e-13	NA	4.8e-12	NA	1.3e-13
14	METSIM	Adipose	0.0526	0.0208	8.4e-04	0.027	0.020	0.026	0.022	0.019	5.5e-05	4.5e-04	7.8e-05	2.8e-04	5.7e-04
15	ROSMAP	Brain Pre-frontal Cortex	0.1288	0.0318	2.1e-07	0.055	0.054	0.054	0.062	0.066	1.3e-07	1.6e-07	1.7e-07	2.0e-08	6.4e-09
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0434	0.0268	4.6e-03	0.026	0.009	0.005	NA	0.019	6.0e-04	3.3e-02	8.0e-02	NA	2.7e-03
17	TCGA	Ovarian Serous Cystadenocarcinoma	0.0660	0.0380	2.2e-03	-0.001	0.033	0.034	NA	0.014	4.1e-01	2.7e-03	2.4e-03	NA	3.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Average weekly fortified wine intake	12.5	14.6	20.5	3.6	4.0	4.5	4.2	4.0	4.2	4.4	4.3	3.4	4.5	4.2	4.0	4.2	2.2	4.0	1.7	1.6
Reason for reducing amount of alcohol drunk: Health precaution	6.6	7.7	11.3	2.7	3.1	3.1	2.7	3.1	3.4	3.0	2.8	3.0	3.1	2.8	2.6	2.9	1.0	3.1	0.8	2.3
Blood Red Count	6.1	59.1	90.2	8.2	8.4	7.6	7.5	8.4	8.0	7.8	7.6	6.7	7.6	7.6	8.2	8.0	1.5	9.5	6.8	8.4
Alcohol usually taken with meals	5.1	8.3	13.8	2.7	3.0	3.7	3.4	3.1	3.1	3.4	3.3	0.8	3.7	3.5	3.0	3.2	1.0	2.4	2.0	0.4
HbA1C	4.8	5.4	8.5	2.3	2.1	2.5	2.7	2.1	2.0	2.6	2.8	0.5	2.5	2.6	2.9	2.8	0.4	2.8	2.5	1.4
Mother’s age at death	4.3	5.4	10.1	2.7	1.8	2.5	2.7	1.8	1.5	2.6	2.8	0.4	2.5	2.5	3.2	2.6	1.8	2.2	3.2	-0.9
Hayfever, allergic rhinitis or eczema	3.3	7.1	11.5	-1.9	-3.4	-2.8	-2.7	-3.3	-2.9	-2.9	-2.7	-3.1	-2.8	-2.9	-2.6	-2.9	0.2	-2.4	0.4	-2.9
Medication: Levothyroxine sodium	3.2	5.5	8.2	2.1	2.3	2.7	2.6	2.2	2.0	2.5	2.5	2.1	2.6	2.6	2.8	2.9	-0.7	2.5	2.3	1.1
Mineral and other dietary supplements	3.2	4.3	7.0	-1.5	-2.3	-2.6	-2.4	-2.3	-2.2	-2.5	-2.3	-1.7	-2.6	-2.2	-2.1	-2.4	-0.7	-2.0	-0.7	-0.8
Ever unenthusiastic/disinterested for a whole week	3.1	3.8	6.3	-1.7	-2.2	-2.0	-2.3	-2.2	-2.2	-2.2	-2.5	-1.4	-2.1	-2.3	-2.2	-2.2	0.0	-2.1	-0.8	-1.1
Reaction Time	2.9	5.5	7.4	-2.2	-2.7	-2.7	-2.5	-2.6	-2.7	-2.5	-2.4	-2.3	-2.7	-2.4	-2.3	-2.6	-0.1	-2.4	-1.1	-2.0
Medication: Atorvastatin	2.9	3.6	6.6	-1.6	-2.4	-2.0	-1.8	-2.4	-2.6	-1.9	-1.6	-1.8	-1.9	-1.6	-1.5	-1.7	-2.0	-1.3	1.2	-2.5
Migraine (self-reported)	2.8	3.5	5.2	-2.3	-2.0	-2.0	-2.2	-2.0	-2.1	-1.9	-2.1	0.5	-2.0	-1.6	-2.0	-2.1	-1.5	-2.1	-1.2	-1.8
Lung FVC	2.7	13.6	19.5	3.1	4.1	4.3	4.3	4.1	4.3	4.3	4.2	1.8	4.4	4.4	4.0	4.3	1.2	3.4	1.6	2.1
Relative age voice broke	2.7	4.1	6.4	-2.0	-2.5	-2.1	-1.9	-2.5	-2.2	-2.2	-2.1	-1.9	-2.1	-2.1	-1.7	-1.9	-1.9	-1.8	-0.5	-2.0
Breast Cancer	2.6	6.1	12.0	-3.3	-2.4	-2.4	-2.6	-2.4	-1.9	-2.6	-2.3	-1.5	-2.4	-2.6	-2.7	-2.7	-0.2	-3.5	-3.1	-1.8
Age at First Birth	2.5	3.6	7.3	2.6	1.7	1.9	1.4	1.7	2.0	1.8	1.6	0.7	2.0	2.2	2.2	2.0	0.8	1.9	2.7	1.9
Hand grip strength (left)	2.5	6.5	10.9	1.1	3.0	3.1	3.0	3.0	3.3	3.0	3.0	1.5	3.1	2.9	2.3	2.8	2.0	1.3	-2.2	0.5
Breastfed as a baby	2.5	3.2	4.7	2.1	1.6	1.9	2.1	1.6	1.9	1.9	2.0	1.3	2.1	2.0	2.0	2.2	-0.4	1.6	1.7	0.3
Alzheimer’s Disease (in mother)	2.4	2.8	4.5	2.1	1.6	1.7	1.5	1.6	1.6	1.5	1.5	1.9	1.7	1.4	1.7	1.6	1.5	1.6	1.8	1.7
Allergy	2.4	5.5	9.2	2.0	2.9	2.4	2.2	2.9	2.7	2.4	2.3	2.5	2.3	2.4	2.2	2.5	-0.1	2.3	0.0	3.0
Had other major operations	2.3	2.8	5.8	2.0	1.6	1.5	1.5	1.7	1.6	1.6	1.6	1.7	1.6	1.6	2.0	1.5	2.4	1.6	1.6	1.4
Length of working week for main job	2.3	2.6	8.6	-2.1	-1.1	-1.3	-1.7	-1.2	-0.8	-1.4	-1.6	-1.5	-1.2	-1.2	-2.0	-1.7	0.6	-2.2	-2.9	-0.9
Blood clot in the leg (DVT)	2.3	3.0	4.2	-1.6	-1.7	-2.0	-1.8	-1.7	-1.9	-1.8	-1.7	-1.7	-2.0	-1.7	-2.0	-1.9	-1.1	-1.8	-1.4	-1.2
Commuting to job workplace: Cycle	2.3	2.8	5.4	0.7	1.5	2.3	1.7	1.5	1.7	2.0	2.0	1.5	2.3	2.0	1.8	1.9	0.9	1.5	1.0	-0.8
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	4.0	-1.6	-1.7	-2.0	-1.7	-1.8	-1.9	-1.8	-1.6	-1.5	-1.9	-1.7	-2.0	-1.8	-1.1	-1.7	-1.3	-1.2
Allergy or Eczema	2.1	5.5	8.1	-2.0	-2.8	-2.6	-2.5	-2.8	-2.5	-2.5	-2.3	-2.5	-2.5	-2.5	-2.5	-2.6	0.0	-2.0	-0.8	-2.6
Fed-up feelings	2.1	3.8	6.1	-2.1	-1.6	-2.4	-2.5	-1.8	-1.3	-2.5	-2.1	-1.5	-2.4	-2.4	-2.4	-2.2	-0.6	-1.6	-1.7	1.2
Had menopause	2.0	2.4	4.8	-1.3	-1.8	-1.4	-1.6	-1.8	-2.0	-1.5	-1.7	-1.9	-1.5	-1.3	-1.2	-1.5	-1.0	-1.7	0.0	-2.2
Illnesses of siblings	1.9	2.6	4.9	1.9	1.7	1.7	1.8	1.7	2.2	1.6	1.8	0.5	1.8	1.5	1.8	1.8	0.6	1.6	0.6	1.6
Pulse rate	1.9	3.2	5.0	-1.6	-1.8	-2.0	-1.8	-1.8	-2.2	-1.8	-2.2	-0.9	-2.0	-1.9	-2.0	-2.2	-0.2	-2.1	-1.0	-1.4
Supplements: Fish oil (including cod liver oil)	1.9	2.5	4.1	1.2	1.7	2.0	1.9	1.7	1.6	1.9	1.8	1.3	1.9	1.7	1.8	1.7	1.4	1.3	0.6	0.4
Pack years of smoking	1.9	2.8	7.3	-1.6	-1.9	-1.9	-1.6	-1.9	-2.0	-1.6	-1.8	-1.1	-1.7	-1.5	-1.4	-1.5	-2.7	-1.1	-0.0	-1.6
Severe depression (siblings)	1.8	2.0	5.3	-2.3	-1.4	-1.2	-1.4	-1.4	-1.5	-1.1	-1.3	0.5	-1.1	-1.3	-1.3	-1.2	-1.6	-1.4	-1.1	-2.3
Pack years adult smoking proportion	1.8	2.7	6.8	-1.8	-1.9	-1.8	-1.5	-1.9	-2.0	-1.5	-1.7	-1.0	-1.7	-1.5	-1.4	-1.5	-2.6	-1.0	-0.3	-1.7
Neck or shoulder pain in last month	1.8	2.5	5.2	-0.8	-1.8	-1.9	-2.3	-1.8	-1.5	-2.0	-2.0	-1.1	-1.9	-1.9	-1.8	-1.9	0.6	-1.1	0.3	0.1
Multivitamins +/- minerals	1.7	2.2	3.3	1.7	1.6	1.4	1.6	1.6	1.8	1.4	1.3	1.5	1.4	1.1	1.3	1.3	1.7	1.6	0.6	1.8
Number of incorrect matches in round	1.7	2.9	6.2	-0.1	-2.0	-1.9	-1.9	-2.0	-2.5	-1.8	-2.0	-1.5	-2.0	-1.7	-1.1	-1.7	0.7	-1.2	2.0	-1.1
Exposure to tobacco smoke outside home	1.7	2.3	3.7	-1.6	-1.5	-1.9	-1.9	-1.6	-1.5	-1.7	-1.7	-0.4	-1.9	-1.5	-1.8	-1.8	-0.5	-1.1	-1.3	-0.4
Number of live births	1.6	2.2	7.4	-1.5	-0.3	-1.5	-1.7	-0.4	-0.3	-1.3	-1.6	0.5	-1.4	-1.5	-1.9	-1.6	-0.9	-1.8	-2.7	1.9
Prospective memory result	1.6	1.9	4.7	0.5	1.7	1.3	1.3	1.6	1.3	1.4	1.4	2.2	1.2	1.7	0.8	1.3	-1.5	1.5	-0.3	1.4
Hearing aid user	1.6	1.8	4.3	-0.1	-1.7	-1.4	-1.4	-1.6	-1.8	-1.3	-1.2	-1.7	-1.5	-1.2	-0.8	-1.0	0.2	-0.6	2.1	-1.0
Depression (Nagel 2018)	1.5	2.3	7.7	2.2	1.4	1.0	1.0	1.3	1.2	0.9	1.0	2.5	0.8	0.7	1.2	1.1	1.8	1.7	0.8	2.8
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	6.6	-1.2	-1.8	-1.2	-1.1	-1.8	-1.6	-1.3	-1.1	-2.1	-1.2	-1.0	-1.2	-1.2	-0.6	-0.8	0.4	-2.6
Headache pain in last month	1.5	2.6	3.9	-1.6	-1.5	-1.9	-2.0	-1.5	-1.4	-1.9	-1.8	-0.8	-1.9	-1.6	-2.0	-2.0	-0.2	-1.7	-1.5	-0.0
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	5.7	2.1	1.5	1.7	1.8	1.5	1.7	1.6	1.7	0.6	1.7	1.7	2.1	2.0	-0.1	1.8	2.4	1.5
Forced vital capacity (FVC), Best measure	1.5	5.4	9.8	1.3	2.7	2.9	2.7	2.7	3.1	2.7	2.8	0.2	2.9	2.6	2.4	2.5	1.9	1.7	0.0	1.2
Comparative body size at age 10	1.5	4.1	7.2	0.7	2.7	2.1	2.3	2.7	2.5	2.3	2.4	2.0	2.1	2.1	1.8	2.1	0.7	1.5	-1.4	1.5
Mean time to correctly identify matches	1.5	2.9	4.8	-1.1	-1.8	-2.2	-2.0	-1.8	-2.0	-2.0	-2.0	-1.8	-2.2	-1.7	-1.6	-2.0	0.5	-1.6	-0.5	-0.4
Hypothyroidism (self reported)	1.4	3.3	5.9	2.3	1.6	1.9	1.9	1.6	2.0	1.6	1.7	0.9	1.9	1.7	2.0	2.0	0.6	2.0	2.4	1.9
Forced vital capacity (FVC)	1.4	5.6	11.6	1.2	2.8	2.9	2.7	2.8	3.4	2.7	2.8	0.1	3.0	2.6	2.3	2.6	1.2	1.9	-0.6	1.3
Tense / ‘highly strung’	1.4	2.3	3.8	-1.5	-1.3	-1.7	-1.9	-1.4	-1.1	-1.9	-2.0	-1.6	-1.8	-1.9	-1.8	-1.8	-0.6	-1.3	-0.4	0.8
Crohns Disease (2012)	1.3	2.2	7.8	-1.1	-1.5	-1.4	-1.6	-1.5	-1.2	-1.6	-1.7	-2.8	-1.3	-1.6	-1.3	-1.5	-1.3	-1.2	0.5	-0.3
Number of treatments/medications taken	1.3	2.3	4.2	-2.0	-1.5	-1.7	-1.9	-1.5	-1.7	-1.7	-1.7	0.2	-1.7	-1.5	-1.6	-1.6	-1.1	-1.5	-0.7	-0.6
Sensitivity / hurt feelings	1.3	2.2	6.5	1.9	1.1	1.1	0.8	1.1	1.5	0.9	0.9	1.9	1.1	0.9	1.5	1.4	0.5	1.9	2.5	2.3
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	7.8	0.9	-1.3	-1.4	-1.1	-1.2	-1.8	-1.4	-1.2	-0.6	-1.6	-1.4	-0.5	-1.1	0.1	-0.7	2.8	0.4
Diabetes (mother)	1.3	1.6	3.1	-0.7	-1.0	-1.7	-1.4	-1.1	-1.2	-1.6	-1.3	-0.2	-1.7	-1.8	-1.3	-1.5	1.0	-1.2	-0.9	1.1
Taking other prescription medications	1.3	2.0	3.3	-1.2	-1.5	-1.7	-1.8	-1.5	-1.6	-1.6	-1.7	-0.4	-1.7	-1.7	-1.4	-1.6	-0.1	-1.7	0.2	-0.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.6	10.0	2.0	1.1	0.5	0.5	1.2	1.0	0.5	0.5	1.8	0.4	0.2	1.0	0.6	1.3	0.8	1.0	3.2
Stomach or abdominal pain in last month	1.3	1.6	6.2	0.8	1.4	1.2	1.1	1.4	1.7	1.2	1.2	2.5	1.2	1.0	1.1	1.2	0.5	1.0	-0.5	1.2
Supplements: Glucosamine	1.3	1.7	3.3	1.1	1.4	1.8	1.3	1.4	1.6	1.4	1.3	0.8	1.7	1.0	1.3	1.5	1.1	1.2	1.2	0.7
Neuroticism score	1.3	2.6	4.9	-1.2	-1.7	-2.0	-2.2	-1.8	-1.3	-2.2	-2.0	-0.9	-2.0	-2.2	-1.7	-1.8	-0.1	-1.1	0.3	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.0	7.8	0.6	2.4	2.6	2.4	2.4	2.8	2.4	2.4	0.2	2.6	2.3	1.9	2.1	1.2	1.4	-0.9	0.8
Peak expiratory flow (PEF)	1.3	3.0	7.0	0.4	2.1	2.0	1.8	2.1	2.6	1.8	1.9	1.4	2.0	1.6	1.5	1.6	0.6	1.0	-1.8	1.4
Illnesses of father: Heart disease	1.3	1.8	3.4	-0.1	-1.7	-1.5	-1.8	-1.7	-1.7	-1.5	-1.7	-0.5	-1.4	-1.6	-1.1	-1.4	-1.0	-0.9	1.2	-0.9
Qualifications: nursing, teaching	1.3	2.0	3.8	1.4	1.3	1.9	1.9	1.3	1.7	1.5	1.7	0.3	1.9	1.7	1.6	1.6	0.6	0.9	0.7	0.1
Guilty feelings	1.3	1.9	3.7	-0.8	-1.4	-1.6	-1.9	-1.4	-1.1	-1.7	-1.9	-0.2	-1.6	-1.6	-1.6	-1.7	1.5	-1.2	0.0	0.5
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.2	-0.7	-1.6	-1.5	-1.4	-1.6	-1.2	-1.7	-1.3	-0.9	-1.5	-1.8	-1.1	-1.6	0.8	-0.9	0.0	-0.1
Heart attack/myocardial infarction (self-reported)	1.3	1.7	2.8	-1.7	-1.3	-1.2	-1.6	-1.3	-1.3	-1.3	-1.4	-1.0	-1.2	-1.3	-1.5	-1.3	-1.2	-1.5	-0.6	-1.3
Heart attack	1.2	1.6	2.5	-1.5	-1.3	-1.2	-1.6	-1.3	-1.3	-1.2	-1.4	-0.9	-1.2	-1.2	-1.5	-1.3	-1.2	-1.5	-0.3	-1.2
Osteoporosis (self-reported)	1.2	1.5	3.1	1.7	1.3	1.1	1.1	1.4	1.0	1.2	1.2	0.9	1.1	1.2	1.1	1.4	0.9	1.2	1.0	1.8
Smoking status: Current	1.2	1.9	3.0	-1.7	-1.0	-1.7	-1.5	-1.1	-1.2	-1.6	-1.5	0.3	-1.7	-1.5	-1.7	-1.5	-0.4	-1.3	-1.2	1.1
Waist Hip Ratio (WHR)	1.1	4.8	12.2	-2.0	-2.4	-2.4	-2.2	-2.5	-2.3	-2.3	-2.1	-3.5	-2.3	-1.9	-2.0	-2.0	-2.4	-1.6	0.3	-1.6
Hand grip strength (right)	1.1	3.1	6.8	0.1	2.0	2.1	2.0	1.9	2.4	2.0	2.1	1.1	2.1	1.9	1.6	2.0	0.3	0.7	-2.6	-0.0
Mouth/teeth dental problems	1.1	1.8	7.2	1.5	1.3	1.3	1.3	1.4	1.9	1.0	1.3	0.8	1.3	0.9	1.1	1.0	2.7	0.6	-0.4	1.3
Mouth/teeth dental problems: Dentures	1.1	1.8	4.6	-1.3	-1.3	-1.5	-1.3	-1.4	-2.1	-1.2	-1.4	-0.2	-1.6	-1.1	-1.2	-1.2	-1.8	-1.2	-0.6	-1.4
Health satisfaction	1.1	1.4	2.5	-1.0	-0.9	-1.3	-1.5	-1.0	-1.0	-1.4	-1.5	0.2	-1.4	-1.3	-1.6	-1.3	-0.3	-1.4	-1.5	0.4
Illnesses of siblings: Diabetes	1.1	1.4	2.3	-1.0	-1.2	-1.2	-1.3	-1.2	-1.1	-1.4	-1.4	-0.8	-1.2	-1.3	-1.5	-1.5	-0.2	-1.2	-1.1	-0.1
Long-standing illness, disability or infirmity	1.1	1.7	3.7	1.3	1.3	1.3	1.3	1.3	0.8	1.4	1.3	1.9	1.3	1.1	1.5	1.5	0.2	1.3	1.3	0.7
Number of self-reported non-cancer illnesses	1.1	1.8	2.7	-1.6	-1.4	-1.6	-1.6	-1.5	-1.5	-1.6	-1.6	0.5	-1.6	-1.4	-1.4	-1.5	-1.2	-1.1	-0.6	-0.3
Ever had prostate specific antigen (PSA) test	1.1	1.2	2.4	-1.5	-0.9	-1.4	-1.2	-0.9	-0.8	-1.3	-1.3	-1.2	-1.3	-1.1	-1.2	-1.1	-0.7	-1.4	-0.7	0.4
Prostate Cancer	1.0	1.5	2.8	-0.7	-1.5	-1.3	-1.1	-1.5	-1.7	-1.4	-1.4	-1.0	-1.4	-1.2	-1.1	-1.3	-0.4	-1.0	-0.4	-1.4
Neuroticism (2016)	1.0	1.4	5.2	1.1	1.2	0.9	0.9	1.2	1.3	0.8	0.9	1.6	0.9	1.0	1.0	1.2	0.6	1.5	0.4	2.3
Smoking Status	1.0	2.4	4.1	-1.5	-1.6	-1.9	-2.0	-1.7	-1.7	-1.8	-1.9	-1.2	-1.9	-1.6	-1.5	-1.7	-0.3	-1.2	0.4	0.1
Cardiovascular Disease	1.0	3.4	5.1	-2.3	-1.9	-2.0	-1.9	-1.9	-2.0	-2.0	-2.0	-0.6	-2.0	-1.5	-2.2	-2.0	-1.5	-1.8	-1.7	-1.4
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	7.9	0.2	2.2	2.4	2.1	2.1	2.8	2.1	2.2	-0.2	2.4	2.1	1.6	1.9	0.4	1.3	-1.4	0.6
Depression (self-reported)	1.0	1.1	2.2	-0.7	-1.3	-1.0	-1.4	-1.3	-1.0	-1.3	-1.3	-0.8	-1.1	-1.5	-1.2	-1.2	-0.3	-1.0	-0.2	-0.6
Age at last live birth	1.0	1.4	3.5	-1.2	-1.1	-1.0	-1.2	-1.1	-1.1	-1.2	-1.3	-1.9	-1.1	-1.2	-1.3	-1.3	-0.5	-1.7	-0.6	-0.7
Loneliness, isolation	1.0	1.4	2.9	-0.3	-1.2	-1.7	-1.6	-1.2	-1.1	-1.6	-1.6	-0.1	-1.6	-1.4	-1.2	-1.5	0.1	-0.6	0.4	0.9
Commuting to job workplace: Walk	1.0	1.0	1.8	0.7	1.1	1.0	1.2	1.1	1.1	1.2	1.3	0.9	1.2	1.3	1.1	1.2	-0.3	0.7	-0.8	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	8.7	0.0	1.0	0.1	0.2	0.9	1.3	0.1	-0.1	1.3	0.1	-0.2	-0.1	-0.1	1.5	-0.3	-2.0	3.0
Osteoarthritis (self-reported)	1.0	1.3	2.6	-0.3	-1.2	-1.5	-1.4	-1.1	-1.6	-1.4	-1.5	-0.6	-1.6	-1.1	-1.1	-1.3	-0.0	-1.1	0.7	0.4
Eye problems/disorders: Glaucoma	1.0	1.1	1.9	0.7	0.9	1.1	1.4	0.9	0.7	1.3	1.3	0.6	1.2	1.3	1.3	1.3	-0.1	1.2	1.2	-0.3
Risk taking	1.0	1.4	5.3	-1.9	-1.2	-0.5	-0.8	-1.2	-1.0	-0.8	-0.8	-0.1	-0.6	-0.9	-1.1	-0.9	-2.1	-0.8	-1.0	-2.3
Age started oral contraceptive pill	1.0	1.2	2.2	1.3	1.3	1.2	1.2	1.3	1.1	1.4	1.2	-0.1	1.2	1.5	1.2	1.2	0.1	1.2	0.0	0.6
Average weekly spirits intake	0.9	1.2	3.9	-1.7	-0.9	-1.1	-1.1	-1.0	-1.0	-1.0	-1.0	1.1	-1.1	-1.1	-1.0	-0.9	-2.0	-0.5	-0.3	-0.3
Relative age of first facial hair	0.9	1.8	3.7	-1.5	-1.5	-1.5	-1.2	-1.6	-1.4	-1.4	-1.2	-1.9	-1.3	-1.2	-1.1	-1.1	-1.6	-0.9	0.2	-1.5
Falls in the last year	0.9	1.2	2.1	0.9	1.2	1.2	1.0	1.2	1.5	1.1	1.0	1.2	1.3	1.1	1.0	1.3	0.1	1.0	1.1	1.3
Exposure to tobacco smoke at home	0.9	1.0	2.0	-1.2	-0.8	-1.0	-1.2	-0.9	-0.9	-0.9	-1.1	-0.9	-1.0	-0.8	-1.2	-1.0	-0.6	-1.4	-0.9	-0.7
Average weekly red wine intake	0.9	1.3	2.5	0.9	1.1	1.6	1.3	1.2	1.1	1.4	1.3	-0.5	1.6	1.3	1.4	1.3	0.6	0.7	0.9	-0.5
Ulcerative Colitis (UC)	0.8	1.5	3.2	1.2	1.1	1.1	1.3	1.1	1.2	1.0	1.2	1.5	1.0	1.1	1.4	1.2	-0.2	1.8	1.1	1.4
Verbal and Numeric Reasoning (VNR)	0.8	1.8	7.4	1.9	1.3	1.3	1.1	1.4	1.4	1.2	1.1	0.2	1.3	1.4	1.4	0.9	2.7	0.5	0.6	1.2
Hearing difficulty/problems: Yes	0.8	1.2	3.7	0.2	-1.4	-1.3	-1.3	-1.3	-1.5	-1.0	-1.1	-0.4	-1.2	-1.0	-0.6	-0.9	0.9	-0.8	1.9	-0.7
Current tobacco smoking	0.8	1.3	2.2	-1.5	-0.9	-1.4	-1.2	-1.0	-1.1	-1.3	-1.2	0.4	-1.4	-1.3	-1.3	-1.2	-0.5	-1.0	-0.9	0.7
Hearing difficulty/problems with background noise	0.8	1.3	2.6	0.4	-1.2	-1.3	-1.4	-1.1	-1.6	-1.1	-1.5	-0.2	-1.3	-1.3	-0.9	-1.0	0.2	-0.7	1.6	0.1
Happiness	0.8	1.0	1.4	-1.1	-0.9	-1.2	-1.1	-0.9	-0.9	-1.2	-1.0	-0.8	-1.2	-1.1	-1.0	-0.9	-0.5	-1.2	-0.9	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.6	-1.5	-0.9	-1.1	-1.5	-1.0	-0.7	-1.3	-1.6	-0.2	-1.1	-1.5	-1.6	-1.3	-0.5	-1.0	-0.4	0.4
Medication: Amlodipine	0.8	1.1	1.9	-1.2	-1.1	-1.3	-1.3	-1.1	-0.8	-1.4	-1.3	-0.0	-1.2	-1.2	-1.2	-1.3	-0.3	-1.0	-0.7	0.2
Heart disease (mother)	0.8	0.9	1.8	0.3	1.2	1.0	1.1	1.1	0.5	1.3	1.3	0.7	1.1	1.1	1.3	1.3	-0.5	0.9	0.3	-0.1
Miserableness	0.8	1.5	2.3	-0.2	-1.1	-1.3	-1.4	-1.1	-1.1	-1.5	-1.5	-0.5	-1.4	-1.5	-1.1	-1.3	1.5	-1.0	0.8	1.2
Financial situation satisfaction	0.8	1.0	2.7	1.0	1.1	0.7	0.7	1.2	1.0	0.9	1.0	1.6	0.7	0.9	0.9	0.9	0.9	1.4	-0.7	0.8
Medication: Bendroflumethiazide	0.8	1.2	1.9	-1.4	-0.9	-1.2	-1.3	-1.0	-1.1	-1.1	-1.1	0.7	-1.2	-0.9	-1.3	-1.3	0.2	-1.3	-1.3	-0.6
Medication: Lisinopril	0.8	1.0	4.7	-1.7	-0.7	-0.7	-0.6	-0.7	-0.7	-0.7	-0.7	0.5	-0.6	-0.9	-1.0	-0.8	-0.9	-0.8	-2.2	-1.5
Illnesses of father: High blood pressure	0.8	1.0	4.3	-0.6	-0.3	-0.7	-1.0	-0.4	-0.1	-1.0	-1.2	-0.0	-0.8	-1.1	-1.4	-0.9	0.7	-1.1	-2.1	1.0
Coronary Artery Disease (CAD)	0.7	0.8	2.4	0.1	0.6	1.1	1.5	0.7	0.5	1.0	1.4	1.3	1.0	1.0	1.0	0.9	0.0	0.6	0.2	-0.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	4.2	0.8	0.7	0.9	0.6	0.7	0.9	0.7	0.9	2.0	0.8	0.4	0.7	0.6	0.7	1.2	0.0	0.8
Nervous feelings	0.7	1.3	2.5	0.3	-1.3	-1.3	-1.2	-1.3	-1.2	-1.4	-1.3	-1.1	-1.3	-1.4	-1.0	-1.1	0.6	-0.7	1.6	0.5
Pain all over the body in last month	0.7	0.8	3.0	-1.6	-0.4	-0.5	-0.6	-0.5	-0.1	-0.6	-0.6	1.1	-0.6	-0.9	-0.8	-0.6	-1.7	-0.5	-1.7	-0.1
Medication: Ramipril	0.7	0.9	1.9	0.4	0.9	0.8	0.8	0.8	0.9	0.8	0.6	1.3	0.8	0.9	0.9	0.9	-1.4	1.1	1.0	0.8
Pulse wave Arterial Stiffness index	0.7	0.8	5.1	-1.8	-0.3	-0.5	-0.2	-0.4	-0.5	-0.5	-0.5	0.1	-0.6	-0.4	-0.8	-0.5	-2.3	-0.5	-1.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.6	-1.5	-1.1	-1.0	-0.7	-1.1	-1.2	-0.7	-0.7	-0.6	-0.8	-0.6	-0.6	-0.6	-1.3	-0.4	0.3	-1.6
Wheeze or whistling in the chest in last year	0.7	1.3	3.5	-0.6	-1.4	-1.3	-1.0	-1.4	-1.9	-1.1	-1.2	-0.1	-1.3	-0.8	-0.7	-1.1	0.5	-1.2	0.1	-1.8
Age at first live birth	0.7	1.3	2.7	0.8	0.7	1.6	1.5	0.8	1.1	1.2	1.4	-1.1	1.5	1.4	1.2	1.2	0.2	0.5	0.7	-1.1
Shortness of breath walking on level ground	0.7	0.8	1.6	-0.4	-0.9	-1.1	-0.8	-0.9	-1.2	-1.1	-1.1	0.7	-1.2	-1.2	-1.0	-1.0	-0.1	-0.9	-0.3	0.2
Hypertension (Self-reported)	0.7	2.1	3.2	-1.8	-1.4	-1.7	-1.6	-1.4	-1.3	-1.7	-1.7	-0.1	-1.6	-1.2	-1.7	-1.6	-1.6	-1.1	-1.0	-0.6
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.9	-0.3	1.1	0.9	0.9	1.1	1.4	0.8	0.9	0.6	1.0	0.6	0.7	0.7	0.7	0.0	-1.7	-0.0
Back pain experienced in last month	0.7	1.1	2.6	-0.6	1.2	0.8	0.8	1.1	1.6	0.8	1.0	0.2	0.9	0.6	0.5	0.9	-1.6	0.9	-1.3	1.5
Breast cancer (self-reported)	0.7	0.9	1.8	-1.1	-0.9	-1.1	-1.3	-1.0	-0.7	-1.1	-1.1	0.3	-1.0	-0.8	-1.2	-1.1	-0.8	-0.8	-0.7	0.1
Neuroticism (Nagel 2018)	0.6	1.4	7.0	-0.3	-0.8	-1.3	-1.4	-0.9	-0.5	-1.5	-1.3	0.4	-1.3	-1.4	-0.9	-0.9	-0.3	-0.1	1.2	2.6
Irritable Bowel Disease (IBD)	0.6	1.3	3.3	1.1	1.0	1.1	1.2	0.9	1.2	0.9	1.1	0.1	1.1	1.0	1.4	1.2	-0.8	1.8	1.5	1.2
Ovarian Cancer	0.6	0.8	2.0	-0.3	-1.0	-0.9	-0.8	-0.9	-1.4	-0.7	-0.8	-1.3	-0.9	-0.9	-0.6	-0.9	-0.3	-0.7	0.6	-1.0
HDL Cholesterol	0.6	1.0	2.4	0.2	-1.1	-1.2	-0.9	-1.0	-1.2	-1.0	-0.9	-1.4	-1.1	-1.1	-1.0	-1.3	1.6	-0.3	0.4	-0.3
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.9	0.5	1.1	0.6	0.1	1.2	0.8	0.8	0.4	0.9	0.6	0.9	0.6	0.8	1.4	0.5	-0.6	1.3
Ulcerative Colitis	0.6	0.9	1.8	0.7	0.8	0.9	1.0	0.8	1.0	0.9	0.9	-0.1	1.0	0.9	0.9	1.0	-1.1	1.3	1.3	0.6
Lung FEV1/FVC ratio	0.6	3.2	11.0	-3.2	-1.3	-1.0	-1.6	-1.3	-0.9	-1.3	-1.4	-1.4	-1.0	-1.2	-2.1	-1.7	-1.5	-1.8	-3.3	-2.2
High blood pressure	0.6	1.8	3.3	-1.8	-1.2	-1.5	-1.5	-1.2	-1.2	-1.4	-1.6	0.1	-1.4	-0.9	-1.6	-1.5	-1.7	-0.9	-1.1	-0.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.4	0.9	1.1	1.2	1.4	1.1	0.9	1.1	1.2	1.4	1.0	0.7	0.7	0.9	1.5	0.4	-0.8	0.5
Number of full brothers	0.6	0.8	1.7	-0.7	-0.7	-1.0	-1.1	-0.7	-0.7	-0.8	-0.8	0.1	-0.9	-0.9	-1.1	-1.1	1.3	-1.0	-1.0	-0.6
Number of children fathered	0.6	0.6	5.0	-0.8	-0.2	-0.3	-0.4	-0.3	-0.2	-0.4	-0.6	1.3	-0.3	-0.4	-0.8	-0.5	-0.2	-1.0	-2.2	-0.5
Medication: Allopurinol	0.6	0.8	3.6	1.1	0.0	-0.5	-0.6	0.1	0.2	-0.4	-0.5	1.5	-0.4	-0.4	-0.1	-0.3	1.9	0.1	0.9	1.9
Supplements: Vitamin C	0.6	0.7	6.3	-0.8	-0.4	-0.1	-0.2	-0.5	-0.5	-0.2	-0.4	-1.3	-0.2	-0.2	-0.2	-0.1	-2.5	-0.1	-0.2	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	5.9	0.3	1.0	0.5	0.3	0.9	1.3	0.3	0.2	0.4	0.5	0.0	0.2	0.3	0.1	0.6	-0.6	2.4
Illnesses of father: None of the above (group 1)	0.6	0.7	1.6	-0.8	0.7	0.8	1.2	0.7	1.0	0.9	1.3	0.2	0.9	0.7	0.7	0.8	-0.4	0.5	-1.2	-0.7
Vascular/heart problems diagnosed by doctor	0.6	1.5	2.6	1.6	1.0	1.5	1.5	1.0	0.9	1.4	1.6	-0.6	1.4	0.9	1.6	1.5	1.0	0.9	1.3	-0.2
Alcohol drinker status: Previous	0.6	0.7	2.9	0.2	0.6	0.8	0.7	0.5	0.7	0.6	0.6	1.1	0.7	0.7	0.5	0.8	-1.7	1.1	0.9	0.4
Depressed Affect (Nagel 2018)	0.5	1.0	3.6	-0.4	-0.6	-1.2	-1.3	-0.7	-0.6	-1.3	-1.1	0.2	-1.2	-1.3	-0.9	-1.0	0.4	-0.5	-0.0	1.9
Alzheimer’s Disease (including proxy)	0.5	0.7	2.0	1.2	0.7	0.6	0.4	0.6	0.7	0.5	0.6	1.4	0.6	0.6	0.6	0.6	1.3	0.3	0.9	1.2
Bipolar Disorder (2011)	0.5	0.5	1.8	1.0	0.3	0.6	0.6	0.4	0.4	0.6	0.6	0.2	0.6	0.6	1.2	0.8	0.8	0.1	1.3	-0.3
Triglycerides	0.5	0.9	2.0	0.4	1.4	1.0	1.0	1.4	0.8	1.1	0.9	0.2	0.9	1.0	0.4	0.8	1.1	0.4	-0.6	1.2
Chronotype (morning person)	0.5	1.2	7.5	-0.8	0.8	0.7	0.6	0.7	1.4	0.7	0.9	0.1	0.9	0.5	0.1	0.7	-2.2	0.1	-2.7	-0.3
Systolic blood pressure, automated reading	0.5	1.4	4.1	-0.8	-0.9	-1.4	-1.3	-0.9	-1.4	-1.3	-1.5	-0.0	-1.5	-1.1	-1.5	-1.3	-2.0	-0.6	-0.5	0.8
Medication: Co-codamol	0.5	0.6	3.8	0.3	-0.5	-0.6	-0.5	-0.6	-0.7	-0.6	-0.7	-0.6	-0.6	-0.7	-0.1	-0.3	-2.0	0.1	1.4	0.7
Serious illness, injury or assault to yourself	0.5	0.6	1.3	-0.1	0.7	0.9	1.0	0.7	0.6	0.9	1.1	1.1	0.9	0.9	0.9	0.8	0.9	0.5	-0.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.7	-0.8	-0.7	-1.0	-1.3	-0.9	-0.8	-1.0	-1.0	-0.4	-1.1	-1.1	-1.2	-0.9	-0.1	-0.6	-0.9	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.8	-0.3	-0.5	-0.8	-1.1	-0.5	-0.2	-1.1	-1.4	-0.6	-1.0	-0.9	-1.6	-1.2	0.8	-0.7	-1.9	1.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	6.6	1.2	0.3	0.1	-0.1	0.3	0.3	-0.1	-0.0	1.8	-0.0	-0.1	0.4	0.1	2.6	0.1	0.6	1.5
Medication: Cholesterol lowering	0.5	0.8	3.0	-0.1	-0.9	-1.0	-1.1	-0.9	-0.9	-0.9	-1.0	-1.3	-0.9	-0.5	-0.4	-0.7	-0.8	-0.3	1.7	0.1
Illnesses of mother	0.5	0.6	1.6	-0.5	-0.8	-0.6	-0.8	-0.8	-0.5	-0.8	-0.9	-0.0	-0.7	-0.7	-0.8	-0.9	0.2	-1.3	-1.0	-0.5
Pulse wave peak to peak time	0.5	0.6	3.9	1.6	0.2	0.5	0.2	0.3	0.6	0.4	0.4	-0.3	0.5	0.3	0.7	0.4	2.0	0.3	1.1	0.4
Medication: Seretide 50 evohaler	0.5	0.6	1.3	-0.3	-0.6	-0.8	-0.9	-0.6	-1.0	-0.7	-0.9	-0.5	-0.9	-0.6	-1.1	-0.8	-0.6	-1.1	-0.6	0.3
Alcohol intake frequency.	0.5	1.2	2.4	0.5	1.4	1.2	0.9	1.3	1.5	1.1	0.9	1.2	1.1	1.0	0.5	1.0	-1.0	1.1	-0.9	1.6
Chest pain or discomfort	0.5	0.7	1.6	-0.0	0.5	1.0	1.0	0.6	0.7	0.8	1.0	1.3	1.0	0.9	1.1	0.8	0.9	0.7	0.1	-0.9
Leg pain on walking	0.5	0.6	1.6	-0.6	-0.5	-0.8	-0.9	-0.6	-0.7	-0.9	-0.9	-0.2	-0.9	-0.8	-1.3	-0.9	0.0	-0.8	-1.0	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.5	-0.5	-0.7	-0.8	-0.7	-0.7	-1.2	-0.6	-0.5	0.7	-0.8	-0.5	-0.6	-0.8	1.1	-0.8	0.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.0	-0.0	1.0	1.2	1.4	1.0	1.1	1.2	1.3	-0.3	1.2	1.1	1.0	1.2	-0.4	1.1	-0.2	0.2
Medication for cholesterol	0.5	0.7	5.4	0.9	0.3	0.4	0.3	0.3	0.3	0.4	0.2	-2.3	0.4	0.1	0.5	0.6	0.3	0.6	1.9	0.5
Asthma (self-reported)	0.5	1.1	2.2	-1.1	-1.0	-1.0	-1.0	-1.0	-0.8	-1.0	-1.2	-0.4	-0.9	-1.1	-1.1	-1.2	-0.2	-1.5	-1.2	-1.1
Wears glasses or contact lenses	0.5	0.5	0.9	0.0	-0.7	-0.9	-0.8	-0.7	-0.8	-0.9	-0.9	0.3	-1.0	-0.6	-0.6	-0.8	0.9	-0.9	0.5	0.0
Ever depressed for a whole week	0.5	0.6	2.0	-1.4	-0.7	-0.5	-0.8	-0.7	-0.7	-0.5	-0.9	-0.8	-0.5	-0.3	-0.9	-0.6	-0.1	-0.8	-1.1	-1.0
Supplements: Calcium	0.5	0.5	2.0	0.2	0.6	0.8	0.9	0.6	0.6	0.7	0.9	1.4	0.7	0.7	0.6	0.6	0.7	0.2	0.0	-0.3
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.3	1.5	0.6	1.0	0.8	0.7	0.9	0.9	0.7	0.4	1.1	1.2	1.4	0.7	2.1	-0.0	1.6	-0.9
LDL Cholesterol	0.4	0.7	1.4	0.1	1.2	0.9	0.8	1.2	1.1	0.9	0.8	-0.7	0.9	0.9	0.5	0.8	0.6	0.4	-0.3	1.0
Blood Platelet Count	0.4	5.2	14.2	-2.2	-2.6	-2.2	-2.2	-2.5	-2.9	-2.0	-2.3	-0.9	-2.2	-2.1	-2.1	-2.5	0.4	-2.2	-1.4	-3.8
Heel T-Score	0.4	2.8	15.9	0.1	2.2	0.8	0.9	2.1	1.8	1.1	0.7	2.4	0.8	1.0	0.3	0.8	1.8	0.9	-2.0	4.0
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.1	0.3	0.4	0.6	0.6	0.5	-0.2	1.0	0.6	0.7	0.6	1.0	0.8	0.7	-0.2	0.7	1.0	-1.0
Medication: Metformin	0.4	0.6	3.1	-1.7	-0.2	-0.0	-0.0	-0.2	0.0	-0.1	-0.1	0.9	-0.0	0.1	-0.4	-0.2	-1.1	-0.7	-1.8	-1.0
Maternal smoking around birth	0.4	0.6	1.1	-0.9	-0.5	-0.9	-0.9	-0.5	-0.6	-0.8	-0.9	1.1	-0.9	-0.7	-1.1	-0.9	-0.8	-0.5	-0.8	0.4
Age when periods started (menarche)	0.4	1.0	5.2	-0.5	-1.0	-0.5	-1.0	-1.0	-1.0	-0.8	-1.1	-2.3	-0.6	-0.8	-0.8	-0.8	-1.2	-0.7	1.0	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	7.1	-0.8	-0.2	-0.6	-0.6	-0.3	-0.0	-0.8	-0.9	-0.3	-0.7	-0.7	-1.3	-0.9	1.0	-0.5	-2.7	0.9
Qualifications: None of the above	0.4	1.0	2.1	-0.6	-0.5	-1.4	-1.0	-0.6	-0.8	-1.1	-1.2	0.3	-1.4	-1.2	-0.9	-1.0	-1.2	-0.6	-0.4	1.5
Hair/balding pattern: Pattern 3	0.4	0.6	2.7	-0.7	-0.6	-0.5	-0.6	-0.5	-0.8	-0.6	-1.0	-0.5	-0.6	-0.4	-0.7	-0.8	1.6	-0.8	-0.9	-0.5
Noisy workplace	0.4	0.5	1.2	-0.2	-0.5	-1.0	-0.8	-0.5	-0.8	-0.8	-0.9	-0.1	-1.0	-1.0	-1.1	-0.9	-0.2	-0.1	-0.0	0.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.4	-1.2	-0.5	-0.5	-0.6	-0.6	-0.8	-0.5	-0.8	-0.5	-0.6	-0.4	-0.8	-0.7	-0.7	-0.5	-1.2	-0.8
Loud music exposure frequency	0.4	0.4	1.0	-0.6	-0.7	-0.8	-0.7	-0.6	-1.0	-0.6	-0.7	0.8	-0.7	-0.3	-0.4	-0.7	-0.1	-0.8	-0.0	-0.6
Gout (self-reported)	0.4	0.5	1.7	0.6	-0.3	-0.7	-0.9	-0.3	-0.3	-0.7	-0.9	0.8	-0.6	-0.5	-0.5	-0.7	1.0	-0.4	0.9	1.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.3	-0.3	-0.9	-0.4	-0.5	-0.8	-0.8	-0.5	-0.6	-0.7	-0.4	-0.5	-0.2	-0.6	0.2	-1.2	0.4	-1.5
High blood pressure (siblings)	0.4	0.6	1.2	-1.1	-0.6	-0.7	-0.9	-0.6	-1.1	-0.6	-0.9	0.5	-0.8	-1.0	-1.1	-0.7	-0.9	-0.6	-0.0	-0.5
Medication for pain relief, constipation, heartburn	0.4	0.8	1.6	0.7	0.9	1.2	1.0	0.9	1.3	1.0	1.1	-0.3	1.2	1.1	0.7	1.0	-0.5	0.5	0.2	-0.0
Medication: Ibuprofen	0.4	0.5	1.3	-0.9	-0.7	-0.5	-0.6	-0.8	-0.7	-0.7	-0.5	-1.1	-0.6	-0.8	-0.4	-0.4	-1.1	-0.7	0.4	-0.5
Knee pain experienced in last month	0.4	0.7	2.3	-0.3	-0.7	-0.8	-0.9	-0.8	-1.1	-0.8	-0.9	-1.5	-0.9	-0.7	-1.0	-0.9	0.1	-0.6	0.3	0.0
Ever taken oral contraceptive pill	0.4	0.5	0.8	0.7	0.8	0.7	0.8	0.9	0.8	0.7	0.6	0.1	0.7	0.7	0.9	0.7	0.5	0.6	-0.0	0.9
Pain type(s) experienced in last month: Hip pain	0.4	0.4	1.1	0.6	0.4	0.7	0.6	0.5	0.4	0.6	0.8	0.6	0.7	0.7	0.9	0.8	-0.6	0.6	1.1	-0.3
Alcohol drinker status: Never	0.4	0.5	1.4	0.2	0.9	0.7	0.6	0.9	0.7	0.8	0.7	1.2	0.8	0.7	0.3	0.5	0.6	0.3	-0.5	0.8
Myopia	0.4	0.6	2.2	-1.0	-0.5	-0.3	-0.8	-0.6	0.0	-0.8	-1.0	0.2	-0.5	-0.7	-1.0	-1.0	-0.1	-0.8	-1.5	0.1
Pain experienced in last month	0.4	0.7	1.6	1.0	0.7	0.9	1.3	0.7	0.5	1.0	0.9	0.1	1.0	1.1	0.9	0.9	-0.2	0.8	0.5	-0.3
Worry (Nagel 2018)	0.3	0.7	3.7	-0.6	-0.5	-0.9	-0.9	-0.6	-0.2	-1.1	-0.9	-0.4	-1.0	-1.1	-0.8	-0.7	-0.5	-0.1	0.0	1.9
Fasting Glucose	0.3	0.4	2.9	0.5	0.7	-0.1	0.2	0.7	0.1	0.2	0.2	0.7	-0.2	-0.1	-0.0	0.2	1.0	-0.1	-0.7	1.7
Primary Biliary Cirrhosis	0.3	0.4	1.0	1.0	0.4	0.6	0.7	0.4	0.4	0.6	0.5	-0.4	0.6	0.5	1.0	0.6	-0.3	0.7	0.8	0.2
Systolic Blood Pressure	0.3	1.4	5.2	-1.2	-1.0	-1.0	-1.3	-1.1	-1.3	-1.1	-1.3	-1.2	-1.1	-0.8	-1.2	-1.1	-2.3	-0.8	-0.8	-0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	3.3	0.6	0.5	0.4	0.2	0.4	0.6	0.3	0.2	0.9	0.3	0.1	0.3	0.3	1.8	0.5	-0.5	1.1
Ever had hysterectomy (womb removed)	0.3	0.4	2.0	0.2	0.7	0.1	0.2	0.7	0.6	0.4	0.4	1.4	0.2	0.2	0.3	0.4	-0.9	0.2	-0.4	1.2
Vitamin and mineral supplements	0.3	0.4	0.8	-0.9	-0.6	-0.7	-0.9	-0.6	-0.5	-0.7	-0.6	-0.1	-0.6	-0.5	-0.6	-0.6	-0.8	-0.8	-0.7	-0.2
Supplements: Zinc	0.3	0.3	1.1	0.3	0.1	0.7	0.5	0.1	0.2	0.5	0.6	0.5	0.7	0.3	0.6	0.6	-0.2	0.8	0.5	-1.0
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	2.5	-1.0	-0.3	-0.2	-0.1	-0.3	-0.5	-0.0	0.2	0.7	-0.1	-0.0	-0.1	-0.1	0.4	-0.1	-1.2	-1.6
Qualifications: CSEs or equivalent	0.3	0.4	1.1	-1.0	-0.6	-0.7	-0.5	-0.7	-0.4	-0.7	-0.5	-0.1	-0.7	-0.9	-0.8	-0.7	-0.3	-0.2	-0.8	-0.2
Medication: Atenolol	0.3	0.4	2.0	-0.4	-0.0	-0.4	-0.4	-0.0	0.4	-0.6	-0.4	0.4	-0.4	-0.6	-0.6	-0.5	1.2	-0.9	-0.5	1.4
Chronic bronchitis/emphysema (father)	0.3	0.4	2.7	0.5	-0.5	-0.6	-0.5	-0.5	-0.8	-0.3	-0.6	-0.1	-0.5	-0.3	-0.0	-0.3	0.3	0.2	1.6	-0.5
Hair/balding pattern: Pattern 2	0.3	0.4	2.6	-0.9	-0.0	-0.5	-0.4	-0.0	-0.5	-0.2	-0.2	0.0	-0.5	-0.3	-0.7	-0.4	-0.7	-0.6	-1.6	0.0
Financial difficulties in last 2 years	0.3	0.4	2.4	0.6	-0.1	-0.5	-0.6	-0.0	0.1	-0.4	-0.3	1.2	-0.4	-0.8	-0.3	-0.4	1.6	-0.3	-0.7	0.5
Diabetes (self-reported)	0.3	0.5	1.9	-0.4	0.4	0.8	0.7	0.4	0.8	0.6	0.8	1.4	0.8	0.7	0.6	0.6	-0.8	0.7	-0.5	-0.8
Fluid intelligence score	0.3	0.6	3.2	0.9	0.6	0.8	0.7	0.6	1.2	0.5	0.6	-0.2	0.8	0.8	0.8	0.4	1.8	-0.1	-0.1	0.5
Time employed in main current job	0.3	0.4	1.7	0.8	-0.4	-0.4	-0.3	-0.4	-0.1	-0.6	-0.5	-0.4	-0.4	-0.6	-0.1	-0.3	-1.3	0.0	1.1	0.9
Asthma	0.3	0.5	1.2	-0.9	-0.6	-0.6	-0.7	-0.6	-0.5	-0.7	-0.9	-0.1	-0.6	-0.8	-0.8	-0.8	-0.4	-1.1	-1.1	-0.8
Hair/balding pattern: Pattern 4	0.3	0.8	2.1	0.6	1.0	0.9	0.6	1.0	1.1	1.0	0.8	0.7	1.1	0.9	0.7	1.1	-0.8	1.5	0.3	1.0
Pulse wave reflection index	0.3	0.4	3.7	-0.8	0.3	0.1	0.3	0.2	0.3	0.3	0.6	-0.1	0.3	0.5	0.2	0.6	-1.9	0.6	0.0	-0.4
Glaucoma (self-reported)	0.3	0.3	2.6	-0.2	-0.1	0.3	0.6	-0.1	-0.3	0.4	0.4	-0.3	0.4	0.4	0.4	0.3	-0.6	0.2	0.9	-1.6
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.8	-0.4	-0.0	-0.4	-0.4	-0.1	0.0	-0.4	-0.5	1.3	-0.4	-0.4	-0.7	-0.5	0.3	-0.1	-1.2	1.2
Worry too long after embarrassment	0.3	0.5	3.2	0.7	-0.3	-0.6	-0.7	-0.3	-0.4	-0.5	-0.6	0.1	-0.6	-0.4	0.0	-0.1	-0.5	0.6	1.8	1.5
Qualifications: College or University degree	0.3	0.9	2.3	0.9	0.8	1.2	1.0	0.9	0.9	1.1	1.0	-0.4	1.2	1.3	1.1	0.8	1.5	-0.2	0.7	-0.5
Medication: Blood pressure	0.3	0.5	1.3	-1.2	-0.5	-0.8	-1.0	-0.6	-0.4	-0.7	-0.7	-0.8	-0.7	-0.4	-0.7	-0.7	-1.0	-0.3	-0.5	-0.6
Angina (self-reported)	0.3	0.4	1.3	0.1	0.9	0.5	0.5	0.8	0.6	0.6	0.5	1.1	0.6	0.8	0.4	0.6	-0.3	0.3	-0.1	0.9
Medication: Omeprazole	0.3	0.4	2.8	0.0	-0.5	-0.5	-0.4	-0.5	-0.2	-0.7	-0.3	0.2	-0.6	-0.8	-0.3	-0.7	1.7	-0.2	-0.5	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	3.9	-0.4	0.3	-0.2	-0.2	0.2	-0.1	-0.2	-0.4	0.1	-0.3	-0.3	-0.8	-0.3	0.6	-0.7	-2.0	0.6
Suffer from ‘nerves’	0.3	0.5	1.1	-0.7	-0.4	-0.6	-0.8	-0.5	-0.4	-0.8	-1.0	0.1	-0.7	-1.0	-1.0	-0.8	0.2	-0.3	-0.5	0.8
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.9	-0.3	-0.5	-0.4	-0.8	-0.5	-0.6	-0.6	-0.8	0.9	-0.6	-0.7	-0.6	-0.7	-0.1	-0.2	0.5	0.5
Ever had bowel cancer screening	0.3	0.4	1.4	0.3	-0.2	-0.5	-0.8	-0.1	-0.1	-0.6	-0.6	0.0	-0.5	-0.6	-0.4	-0.7	1.2	-0.4	-0.4	1.1
Eye problems/disorders: Cataract	0.3	0.3	1.6	-0.4	-0.3	-0.5	-0.6	-0.3	-0.2	-0.6	-0.6	0.6	-0.5	-0.5	-0.8	-0.7	0.3	-0.4	-1.3	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.8	0.2	0.6	0.9	0.5	0.6	0.7	0.7	0.8	0.6	0.8	0.6	0.9	0.7	0.3	0.7	0.4	0.1
Medication: Aspirin	0.3	0.4	2.0	-0.9	-0.0	-0.6	-0.6	-0.1	-0.2	-0.4	-0.6	0.4	-0.5	-0.3	-0.6	-0.4	-1.4	-0.4	-1.0	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.0	0.2	0.7	0.9	0.9	0.7	0.9	0.8	0.9	-1.0	0.9	1.0	0.8	0.8	0.6	0.2	-0.2	-0.0
Average weekly champagne plus white wine intake	0.3	0.4	2.4	-1.6	-0.0	-0.2	-0.3	-0.1	-0.0	-0.2	-0.3	0.2	-0.1	-0.2	-0.6	-0.3	-1.1	-0.8	-1.0	-0.2
Medication: Blood pressure	0.3	0.6	3.8	-1.1	0.2	-0.3	-0.2	0.2	-0.1	-0.2	-0.2	1.9	-0.3	0.1	-0.8	-0.4	-0.1	-0.6	-1.9	0.5
Diastolic blood pressure, automated reading	0.3	1.1	2.9	-0.4	-0.8	-1.2	-1.2	-0.8	-1.4	-1.1	-1.3	0.4	-1.3	-1.0	-1.1	-1.1	-1.7	-0.1	0.2	0.6
Cholesterol lowering medication	0.3	0.4	3.2	0.1	0.5	0.4	0.5	0.5	0.6	0.5	0.5	1.8	0.5	0.7	0.3	0.3	-0.6	-0.2	-0.7	0.3
Basal cell carcinoma (self-reported)	0.3	0.3	2.3	-0.3	0.6	0.4	0.3	0.5	0.4	0.6	0.5	-0.4	0.5	0.8	0.0	0.4	-0.3	0.2	-1.5	-0.3
Bipolar Disorder or Schizophrenia	0.2	0.4	3.1	0.5	-0.1	0.1	0.0	-0.1	-0.3	0.1	-0.1	0.4	-0.0	-0.1	0.7	0.2	-1.7	0.4	1.8	0.2
Schizophrenia (2018)	0.2	0.4	2.9	0.5	-0.1	0.2	0.3	-0.1	-0.1	0.1	0.0	0.5	0.1	0.1	0.8	0.4	-1.2	0.7	1.7	0.4
Schizophrenia vs Biploar Disorder	0.2	0.2	1.6	0.7	0.1	-0.1	0.2	0.1	-0.1	-0.2	-0.2	0.0	-0.2	0.0	0.0	-0.1	1.1	-0.2	0.4	1.3
Alzheimer’s Disease (in father)	0.2	0.3	0.5	-0.1	-0.5	-0.7	-0.6	-0.5	-0.4	-0.7	-0.5	0.1	-0.7	-0.5	-0.4	-0.6	0.0	-0.7	-0.2	0.3
Mean Putamen Volume	0.2	0.3	2.2	-0.9	-0.1	0.5	0.1	-0.1	0.0	0.3	0.3	-0.2	0.5	0.3	0.3	0.2	-0.9	-0.3	-0.1	-1.5
Schizophrenia (2014)	0.2	0.5	5.4	0.9	-0.2	-0.1	0.1	-0.2	-0.7	-0.1	-0.3	-0.2	-0.3	-0.0	0.5	0.1	-1.1	0.5	2.3	0.5
Blood Eosinophil Count	0.2	1.5	3.7	-0.8	-1.5	-1.6	-1.5	-1.5	-1.9	-1.3	-1.4	-0.2	-1.6	-1.1	-0.8	-1.1	0.1	-0.9	0.6	-1.0
Respiratory disease	0.2	0.5	1.6	-0.7	-0.5	-0.6	-0.9	-0.5	-0.5	-0.7	-1.0	0.2	-0.6	-0.7	-0.9	-0.8	0.2	-1.1	-1.3	-0.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.5	-1.0	-0.1	0.6	0.5	-0.0	0.2	0.3	0.3	1.0	0.5	0.3	0.0	0.0	-0.9	-0.1	-1.0	-1.6
Neuroticism	0.2	0.4	3.3	0.1	-0.2	-0.6	-0.7	-0.3	-0.1	-0.7	-0.5	0.3	-0.6	-0.8	-0.3	-0.3	0.5	0.0	0.7	1.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.6	-0.4	-0.4	-0.4	-0.0	-0.4	-0.7	-0.2	-0.0	-0.0	-0.4	-0.3	-0.0	-0.2	-0.2	-0.6	-1.0	-1.3
Medication for hormone replacement therapy	0.2	0.2	1.3	-0.0	-0.4	-0.1	0.0	-0.4	-0.3	-0.2	-0.1	1.1	-0.3	-0.3	-0.1	-0.4	0.4	-0.4	-0.8	-1.0
Diabetes (father)	0.2	0.2	1.4	0.0	-0.5	-0.3	-0.2	-0.5	-0.4	-0.5	-0.4	-1.2	-0.3	-0.3	-0.3	-0.4	-0.0	-0.4	0.7	0.0
Impedance of leg (right)	0.2	0.7	3.0	0.4	-1.1	-0.9	-0.6	-1.1	-1.3	-0.8	-0.6	-1.7	-1.0	-0.7	-0.3	-0.7	0.3	-0.2	0.4	-0.9
Trunk fat percentage	0.2	0.8	2.6	-1.1	-0.6	-0.9	-0.8	-0.6	-0.8	-0.9	-0.9	0.9	-1.0	-0.9	-1.0	-1.0	-0.1	-0.7	-1.6	-0.1
Townsend deprivation index at recruitment	0.2	0.3	1.3	-0.0	-0.4	-0.7	-0.4	-0.4	-0.5	-0.3	-0.3	-0.8	-0.5	-0.5	-0.2	-0.3	1.1	-0.3	-0.2	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.2	0.2	0.1	-0.2	-0.3	-0.0	-0.1	-0.2	-0.3	1.1	-0.3	-0.4	-0.2	-0.1	0.9	0.3	-0.5	0.8
Impedance of leg (left)	0.2	1.1	3.0	-0.2	-1.3	-1.1	-0.9	-1.3	-1.6	-1.0	-0.9	-1.7	-1.2	-1.0	-0.6	-0.9	-0.2	-0.5	0.1	-1.2
Waist circumference	0.2	0.8	1.9	-1.1	-0.2	-1.0	-0.9	-0.4	-0.3	-1.0	-0.9	0.3	-1.0	-0.8	-1.1	-0.9	-0.9	-0.7	-1.2	1.4
Past tobacco smoking	0.2	0.3	3.0	-0.3	0.1	0.6	0.5	0.1	0.6	0.2	0.3	0.4	0.5	-0.1	-0.1	0.1	0.7	-0.5	-1.7	-0.6
Impedance of arm (right)	0.2	0.8	2.3	-0.1	-1.1	-0.8	-0.7	-1.1	-1.5	-0.7	-0.5	-1.3	-0.9	-0.5	-0.4	-0.6	0.3	-0.5	0.6	-1.5
Arm fat percentage (right)	0.2	0.7	3.0	-0.8	-0.4	-1.1	-0.8	-0.5	-0.8	-0.9	-0.9	1.7	-1.0	-0.8	-0.9	-0.8	-0.0	-0.4	-0.8	0.7
Father’s age at death	0.2	0.3	1.6	0.3	0.2	-0.3	-0.4	0.2	0.2	-0.3	-0.3	0.4	-0.3	0.1	-0.3	-0.3	1.3	-0.7	-1.0	1.0
Worrier / anxious feelings	0.2	0.4	1.2	-0.8	-0.6	-0.7	-1.1	-0.7	-0.5	-0.8	-0.9	-0.3	-0.7	-0.5	-1.0	-0.7	-0.4	-0.1	0.0	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.7	0.3	0.3	0.4	0.4	0.4	0.2	0.5	0.6	0.8	0.4	0.4	0.8	0.5	-0.8	0.6	0.5	-0.4
Lung cancer (father)	0.2	0.3	1.2	0.2	0.3	0.5	0.7	0.3	0.1	0.5	0.6	0.8	0.4	0.4	0.6	0.5	-1.1	0.7	0.1	0.0
Birth weight of first child	0.2	0.4	0.9	-0.1	0.9	0.5	0.6	0.8	0.9	0.6	0.8	0.8	0.5	0.8	0.2	0.6	-0.4	0.7	-0.2	1.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	0.7	-0.2	-0.7	-0.4	-0.6	-0.7	-0.1	-0.7	-0.4	-0.8	-0.4	-0.5	-0.6	-0.6	-0.1	-0.4	0.3	-0.1
Medication: Paracetamol	0.2	0.3	0.7	-0.8	-0.4	-0.5	-0.5	-0.4	-0.8	-0.4	-0.6	0.1	-0.6	-0.6	-0.6	-0.5	-0.8	-0.2	-0.8	-0.3
Body fat percentage	0.2	0.7	2.5	-0.9	-0.3	-0.8	-0.7	-0.4	-0.6	-0.8	-0.8	1.3	-0.9	-0.8	-0.9	-0.8	-0.0	-0.5	-1.6	0.4
Leg fat percentage (right)	0.2	0.6	3.6	-0.1	0.2	-0.6	-0.4	0.1	-0.1	-0.5	-0.5	1.9	-0.6	-0.4	-0.6	-0.5	0.2	0.0	-1.2	1.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.5	-0.2	-0.7	-0.2	-0.3	-0.6	-0.7	-0.3	-0.3	0.3	-0.3	-0.1	-0.3	-0.2	-0.3	-0.1	0.6	-1.2
Emphysema/chronic bronchitis	0.2	0.2	2.7	0.3	-0.4	-0.2	-0.2	-0.4	-0.7	-0.2	-0.2	0.1	-0.3	0.2	-0.0	-0.1	0.1	-0.4	1.6	-0.1
Pulse rate, automated reading	0.2	0.5	1.1	0.0	-0.7	-0.8	-0.7	-0.6	-0.9	-0.8	-1.0	0.4	-0.9	-0.9	-0.7	-1.0	0.4	-0.8	-0.8	-0.2
Overall health rating	0.2	0.4	1.1	-0.8	-0.2	-0.5	-0.5	-0.2	-0.4	-0.6	-0.5	1.0	-0.6	-0.7	-0.7	-0.5	-1.1	-0.5	-0.8	0.7
Had major operations	0.2	0.3	0.6	-0.6	-0.3	-0.6	-0.8	-0.3	-0.5	-0.5	-0.6	0.4	-0.6	-0.2	-0.6	-0.4	-0.7	-0.4	-0.6	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	0.0	-0.3	-0.4	-0.3	-0.3	-0.5	-0.3	-0.2	0.6	-0.4	-0.5	-0.4	-0.3	0.7	0.2	-0.8	-0.6
Medication: Aspirin	0.2	0.2	0.7	-0.6	-0.1	-0.5	-0.5	-0.1	-0.1	-0.4	-0.6	0.4	-0.4	-0.2	-0.4	-0.3	-0.9	-0.4	-0.5	0.8
Smoking status: Previous	0.2	0.4	4.1	0.5	-0.2	-0.4	-0.4	-0.2	-0.4	-0.2	-0.3	-0.9	-0.3	0.1	0.3	-0.1	-0.4	0.5	2.0	0.1
Mood swings	0.2	0.4	2.8	0.2	0.5	0.3	-0.1	0.5	0.8	0.1	0.1	1.5	0.3	-0.1	0.3	0.4	0.6	0.6	0.3	1.7
Diabetes diagnosed by doctor	0.2	0.3	2.6	-1.0	-0.3	0.3	0.2	-0.2	0.0	0.1	0.2	0.7	0.3	0.1	-0.1	-0.1	-0.7	-0.0	-0.8	-1.6
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.9	0.3	0.3	-0.3	-0.1	0.3	0.6	-0.2	-0.1	-0.3	-0.1	-0.3	-0.5	-0.3	0.2	0.1	-0.8	1.4
Commuting to job workplace: Public transport	0.2	0.2	2.9	0.0	-0.4	0.1	0.2	-0.3	-0.4	0.1	0.1	-0.5	0.1	0.1	0.4	0.0	0.6	-0.0	0.2	-1.7
High cholesterol (Self-reported)	0.2	0.4	1.1	0.1	-0.9	-0.7	-0.6	-0.8	-1.1	-0.6	-0.6	0.1	-0.7	-0.2	-0.3	-0.5	-0.1	-0.6	0.8	-0.8
Leg fat percentage (left)	0.2	0.7	3.5	-0.5	0.0	-0.7	-0.6	-0.0	-0.3	-0.7	-0.8	1.9	-0.7	-0.6	-0.8	-0.7	-0.1	-0.2	-1.5	1.5
Fractured/broken bones in last 5 years	0.2	0.2	1.9	-0.4	-0.4	-0.2	-0.3	-0.4	-0.4	-0.2	-0.3	-0.5	-0.2	-0.3	0.1	0.1	-0.8	-0.3	1.4	-0.6
Unable to work because of sickness or disability	0.2	0.3	1.4	0.9	0.4	0.1	0.2	0.3	0.3	0.3	0.2	0.9	0.2	0.1	0.4	0.4	-0.3	1.2	0.3	0.5
Heart disease (siblings)	0.2	0.3	1.2	0.1	-0.2	-0.3	-0.2	-0.2	-1.1	-0.0	-0.4	0.3	-0.5	0.0	-0.5	-0.4	0.8	-0.2	-0.8	-1.0
Impedance of whole body	0.2	0.9	4.4	-0.3	-1.2	-0.7	-0.6	-1.1	-1.5	-0.6	-0.5	-1.7	-0.8	-0.6	-0.4	-0.6	-0.0	-0.4	0.1	-2.1
Bipolar Disorder (2018)	0.1	0.1	1.4	0.2	-0.1	-0.0	-0.2	-0.1	-0.3	0.0	-0.3	-0.1	-0.1	-0.3	0.1	-0.1	-1.2	-0.2	0.7	-0.2
Crohns Disease (2017)	0.1	0.3	1.9	0.1	-0.1	0.2	-0.1	-0.2	0.3	-0.1	-0.1	-1.4	0.2	-0.0	0.4	0.1	-1.2	0.6	1.1	0.3
Major Depression (MDD)	0.1	0.1	0.8	-0.1	0.3	0.2	-0.1	0.2	0.2	-0.0	-0.2	-0.5	0.1	0.1	-0.4	-0.1	-0.6	0.6	-0.1	0.9
Body Mass Index (BMI) (2010)	0.1	0.1	1.0	0.1	0.0	0.0	0.0	0.0	-0.4	0.1	-0.0	1.0	-0.0	-0.0	0.1	0.1	-0.1	-0.1	0.1	-0.2
Lupus	0.1	0.2	0.8	0.7	-0.1	-0.5	-0.7	-0.1	-0.0	-0.4	-0.6	-0.2	-0.4	-0.5	-0.1	-0.3	0.4	-0.2	0.7	0.9
Blood White Count	0.1	0.9	3.0	1.0	0.5	0.9	0.9	0.6	0.7	0.9	0.9	1.7	1.0	0.9	0.9	0.8	1.7	0.6	0.4	-0.4
BMI	0.1	0.4	2.5	-0.9	0.2	-0.2	-0.4	0.1	0.1	-0.3	-0.4	1.0	-0.2	-0.3	-0.8	-0.5	0.9	-0.4	-1.6	0.5
Height	0.1	1.4	3.4	-0.1	1.7	0.9	1.0	1.5	1.8	1.0	1.2	-0.2	1.0	0.9	0.7	1.2	-0.4	0.8	-1.6	1.8
Hair Pigment	0.1	1.9	7.0	-1.4	-1.5	-1.0	-1.2	-1.6	-1.0	-1.4	-1.3	-1.8	-1.1	-1.4	-1.3	-1.1	-2.6	-0.6	-0.3	-0.9
Angina	0.1	0.2	1.1	0.1	0.5	0.1	0.2	0.5	0.2	0.2	0.2	1.0	0.2	0.3	0.1	0.2	-0.1	0.0	0.0	1.0
Leg fat-free mass (left)	0.1	0.7	3.8	-1.0	1.0	0.7	0.6	0.9	1.5	0.5	0.6	0.7	0.8	0.5	0.1	0.5	-0.3	0.0	-1.9	0.7
Sitting height	0.1	0.7	2.7	-0.9	0.6	1.0	0.8	0.6	1.2	0.7	0.9	-0.5	0.9	0.5	0.5	0.7	0.5	0.1	-1.6	-0.7
High blood pressure (mother)	0.1	0.1	0.5	-0.5	-0.1	-0.0	0.1	-0.1	-0.2	0.1	0.1	0.0	0.0	0.2	-0.1	0.1	-0.7	0.6	0.6	-0.6
Body mass index (BMI)	0.1	0.5	3.6	-0.6	0.2	-0.4	-0.3	0.2	0.2	-0.4	-0.5	1.9	-0.4	-0.4	-0.6	-0.5	-0.1	-0.2	-1.3	1.3
Leg predicted mass (left)	0.1	0.7	3.7	-1.0	0.9	0.7	0.5	0.8	1.4	0.5	0.5	0.7	0.8	0.4	0.0	0.4	-0.3	-0.0	-1.9	0.6
Trunk fat mass	0.1	0.6	3.6	-1.1	-0.1	-0.6	-0.5	-0.2	-0.2	-0.6	-0.6	1.0	-0.6	-0.6	-0.9	-0.7	-0.3	-0.5	-1.9	0.4
Medication: Simvastatin	0.1	0.1	1.3	0.2	0.2	-0.1	-0.0	0.2	-0.0	0.1	-0.1	1.1	-0.0	0.3	0.3	0.2	-0.5	-0.1	0.4	0.5
Weight	0.1	0.6	4.7	-1.1	0.6	0.0	0.0	0.5	0.8	-0.1	-0.1	0.9	0.0	-0.1	-0.5	-0.1	-0.3	-0.2	-2.2	1.1
Trunk fat-free mass	0.1	0.7	2.5	-0.7	1.1	0.6	0.5	1.0	1.6	0.5	0.5	0.2	0.7	0.5	0.1	0.5	-0.3	0.2	-1.5	1.6
Hip circumference	0.1	0.6	3.2	-0.4	0.7	0.0	0.1	0.6	0.8	-0.1	0.0	1.5	0.0	-0.0	-0.2	-0.0	0.1	-0.2	-1.5	1.8
Alcohol intake versus 10 years previously	0.1	0.2	1.0	0.4	-0.1	0.4	0.1	-0.0	-0.2	0.3	0.2	-0.0	0.4	0.2	0.3	0.3	1.0	0.1	0.5	-0.8
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.5	0.2	0.1	0.8	0.6	0.1	0.5	0.5	0.6	-0.4	0.7	0.6	0.7	0.5	-0.0	-0.3	0.3	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.6	-0.4	-0.4	-0.2	-0.3	-0.4	-0.3	-0.3	-0.2	-0.8	-0.2	-0.4	-0.1	-0.1	-0.5	-0.3	0.3	-0.3
Medication: Lansoprazole	0.1	0.1	0.9	0.1	0.1	-0.0	-0.2	0.1	-0.2	0.1	-0.0	0.9	-0.0	-0.1	0.1	-0.0	0.6	-0.3	0.3	0.2
Impedance of arm (left)	0.1	0.4	3.7	-0.1	-0.8	-0.2	-0.2	-0.8	-1.1	-0.2	-0.1	-1.0	-0.3	-0.1	0.0	-0.2	0.0	-0.1	0.5	-1.9
Arm fat mass (right)	0.1	0.5	2.4	-0.9	0.0	-0.5	-0.5	-0.0	-0.1	-0.5	-0.5	1.6	-0.5	-0.5	-0.7	-0.5	-0.2	-0.3	-1.5	0.8
Trunk predicted mass	0.1	0.8	2.7	-0.6	1.2	0.7	0.6	1.1	1.6	0.6	0.6	0.3	0.8	0.6	0.2	0.6	-0.3	0.3	-1.4	1.6
Standing height	0.1	0.9	4.7	-1.1	0.7	0.8	0.6	0.6	1.2	0.5	0.7	-2.0	0.7	0.6	0.0	0.5	-0.7	-0.2	-2.2	-0.2
Arm fat-free mass (right)	0.1	0.7	5.3	-1.0	0.8	0.5	0.4	0.7	1.4	0.2	0.2	0.2	0.5	0.2	-0.2	0.2	-0.4	-0.1	-2.3	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.4	-0.5	-0.2	-0.1	-0.2	-0.2	-0.1	-0.3	-0.4	0.3	-0.1	-0.6	-0.5	-0.3	0.2	0.0	0.3	0.1
Eye problems/disorders: None of the above	0.1	0.1	0.6	0.7	0.1	0.2	0.4	0.1	0.4	0.0	0.2	-0.5	0.1	-0.0	0.4	0.3	0.6	0.4	0.2	0.4
Whole body fat mass	0.1	0.5	3.5	-0.9	0.2	-0.3	-0.3	0.1	0.1	-0.4	-0.4	1.2	-0.4	-0.3	-0.7	-0.4	-0.1	-0.3	-1.9	0.7
Leg fat mass (right)	0.1	0.5	3.1	-0.4	0.5	-0.1	-0.0	0.4	0.5	-0.1	-0.2	1.8	-0.1	-0.1	-0.3	-0.2	-0.1	0.1	-1.6	1.4
Arm predicted mass (right)	0.1	0.7	5.7	-1.1	0.7	0.4	0.3	0.6	1.3	0.2	0.2	0.1	0.5	0.2	-0.3	0.1	-0.4	-0.3	-2.4	0.7
Comparative height size at age 10	0.1	0.4	3.0	-1.0	0.5	0.1	0.3	0.4	0.3	0.2	0.4	-0.4	0.1	0.2	-0.2	0.2	-1.2	-0.3	-1.7	-0.0
Number of full sisters	0.1	0.2	1.4	-0.4	0.2	-0.1	-0.3	0.2	0.3	0.1	0.1	1.0	0.1	-0.1	-0.2	0.1	-0.2	0.2	-1.2	0.0
Family relationship satisfaction	0.1	0.1	0.3	-0.1	-0.4	-0.3	-0.5	-0.4	-0.2	-0.4	-0.4	-0.3	-0.3	-0.3	0.1	-0.1	0.1	-0.2	0.3	0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.6	-0.5	-0.3	-0.0	-0.2	-0.3	-0.2	-0.3	-0.4	-0.3	-0.1	-0.1	-0.4	-0.2	-0.8	-0.3	0.3	-0.0
Whole body fat-free mass	0.1	0.8	3.3	-0.8	1.1	0.7	0.6	1.1	1.6	0.6	0.6	0.4	0.8	0.5	0.1	0.5	-0.3	0.2	-1.8	1.3
Leg fat-free mass (right)	0.1	0.7	4.4	-1.3	0.9	0.7	0.5	0.8	1.4	0.5	0.5	0.6	0.8	0.3	-0.1	0.4	-0.5	-0.1	-2.1	0.3
Arm fat percentage (left)	0.1	0.6	3.4	-0.8	-0.3	-0.8	-0.6	-0.4	-0.6	-0.7	-0.7	1.8	-0.8	-0.7	-0.8	-0.7	-0.3	-0.2	-1.0	0.4
Whole body water mass	0.1	0.8	3.8	-0.9	1.1	0.7	0.6	1.0	1.6	0.5	0.5	0.4	0.8	0.4	0.1	0.5	-0.4	0.1	-2.0	1.3
Leg predicted mass (right)	0.1	0.8	4.5	-1.3	0.9	0.7	0.5	0.8	1.4	0.5	0.5	0.7	0.8	0.4	-0.1	0.4	-0.5	-0.1	-2.1	0.4
Arm fat mass (left)	0.1	0.4	3.4	-0.7	0.4	-0.1	-0.1	0.3	0.3	-0.1	-0.1	1.9	-0.1	-0.1	-0.3	-0.1	-0.2	0.1	-1.3	0.9
Medication: Paracetamol	0.1	0.1	1.1	-0.7	0.2	-0.0	0.1	0.2	-0.5	0.2	0.1	0.4	-0.1	0.0	-0.1	0.0	-0.2	-0.0	-1.0	-0.4
Ever smoked	0.1	0.2	1.1	-0.3	-0.1	-0.5	-0.4	-0.1	-0.5	-0.1	-0.2	-0.4	-0.4	0.1	-0.0	-0.0	-1.1	0.4	1.1	0.3
Basal metabolic rate	0.1	0.6	4.0	-1.1	0.9	0.5	0.4	0.8	1.3	0.3	0.3	0.5	0.5	0.2	-0.2	0.3	-0.4	-0.1	-2.0	1.0
Arm fat-free mass (left)	0.1	0.6	4.3	-1.0	0.8	0.3	0.2	0.7	1.1	0.2	0.2	0.5	0.4	0.2	-0.2	0.2	-0.3	-0.1	-2.1	1.1
Number of operations (self-reported)	0.1	0.1	0.7	-0.0	-0.2	-0.1	-0.4	-0.2	-0.1	-0.2	-0.3	0.3	-0.2	-0.3	0.3	-0.1	0.3	-0.2	0.9	0.3
Average weekly beer plus cider intake	0.1	0.1	0.9	-0.5	0.0	0.0	0.2	-0.0	0.0	0.1	0.2	0.6	0.0	0.6	0.2	0.0	0.0	0.3	-0.9	-0.5
Irritability	0.1	0.1	0.5	-0.5	-0.2	-0.4	-0.4	-0.3	0.1	-0.4	-0.5	-0.1	-0.3	-0.5	-0.4	-0.4	0.0	-0.0	0.3	0.7
Leg fat mass (left)	0.1	0.5	3.3	-0.4	0.6	-0.0	0.0	0.5	0.5	-0.0	-0.1	1.8	-0.0	-0.0	-0.3	-0.1	-0.2	0.2	-1.7	1.3
Arm predicted mass (left)	0.1	0.6	3.1	-0.7	1.0	0.5	0.5	0.9	1.3	0.5	0.5	0.5	0.6	0.4	0.1	0.4	-0.1	0.1	-1.8	1.1
Rheumatoid Arthritis	0.0	0.1	0.4	-0.4	0.1	-0.0	-0.2	0.1	0.1	-0.1	-0.1	0.3	-0.1	0.1	-0.2	-0.1	-0.6	0.2	-0.0	0.4
Tanning	0.0	0.5	3.5	0.6	-0.8	-0.5	-0.4	-0.7	-1.0	-0.6	-0.4	-0.6	-0.6	-0.7	-0.3	-0.5	0.5	-0.7	1.9	0.4
Birth weight	0.0	0.1	0.7	-0.4	-0.0	0.2	-0.0	-0.0	-0.0	0.1	0.3	0.2	0.2	0.3	-0.2	0.1	0.3	-0.5	-0.5	-0.8
Friendships satisfaction	0.0	0.0	0.1	-0.3	-0.1	-0.3	-0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	-0.1	0.1	0.0	-0.2	-0.1	-0.2	-0.0
Medication: Gliclazide	0.0	0.0	0.3	-0.1	0.0	-0.4	-0.1	0.0	-0.2	-0.1	-0.1	0.3	-0.2	0.0	-0.2	-0.0	-0.4	-0.0	0.2	0.5

Hub : Genes

CNOT8

Models

Trait associations