TWAS hub - CRABP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0602	0.0288	2.4e-03	0.022	0.023	0.015	NA	0.020	1.4e-03	1.2e-03	7.4e-03	NA	2.1e-03
2	TCGA	Lung Squamous Cell Carcinoma	0.0383	0.0163	4.5e-04	0.029	0.031	0.026	NA	0.033	2.4e-04	1.8e-04	4.8e-04	NA	1.2e-04
3	TCGA	Prostate Adenocarcinoma	0.1583	0.0472	4.7e-11	0.050	0.132	0.124	NA	0.097	5.2e-06	1.1e-13	7.2e-13	NA	2.4e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Maternal smoking around birth	6.0	8.6	14.6	-3.8	-1.5	-3.0
Pulse rate	4.8	8.1	12.8	-1.4	-3.6	-3.1
Leg pain on walking	4.3	5.3	9.3	-3.0	-2.3	-1.3
Chronotype (morning person)	4.1	9.4	13.3	-3.6	-3.6	-1.5
Eye problems/disorders: Cataract	4.1	4.7	8.4	-0.6	-2.3	-2.9
Pack years adult smoking proportion	3.2	4.9	8.8	-3.0	-2.2	-1.1
High blood pressure (mother)	3.0	4.2	5.1	-1.7	-2.2	-2.2
Had menopause	3.0	3.8	5.0	2.0	2.2	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.9	3.4	5.7	-0.8	-2.0	-2.4
Blood Red Count	2.7	25.9	36.5	-2.9	-6.0	-5.8
Age when periods started (menarche)	2.5	5.9	12.5	1.7	1.5	3.5
Noisy workplace	2.4	3.0	4.8	-2.2	-1.2	-1.6
Pulse wave Arterial Stiffness index	2.3	2.6	3.6	-1.0	-1.8	-1.9
Pulse wave peak to peak time	2.3	2.7	3.5	1.1	1.9	1.9
Pain type(s) experienced in last month: Hip pain	2.2	2.8	3.7	-1.9	-1.0	-1.9
Pulse rate, automated reading	2.1	6.9	10.0	-2.0	-3.2	-2.6
Ever smoked	2.1	3.6	6.8	2.6	2.0	0.3
Age started oral contraceptive pill	2.1	2.7	3.5	1.8	1.9	1.1
Average weekly fortified wine intake	2.0	2.3	3.2	-1.7	-1.8	-0.9
Hypothyroidism/myxoedema (self-reported)	2.0	3.8	6.1	2.5	2.3	0.4
Medication: Atorvastatin	2.0	2.5	3.3	1.8	1.8	1.0
Pack years of smoking	2.0	3.0	6.2	-2.5	-1.4	-0.8
Body Mass Index (BMI) (2010)	1.9	2.6	4.3	-1.2	-2.1	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	2.7	-1.5	-1.1	-1.7
Cholesterol lowering medication	1.9	2.8	3.7	-1.9	-1.6	-1.5
Ulcerative Colitis (UC)	1.8	3.3	5.5	-2.0	-2.4	-0.6
Prospective memory result	1.8	2.2	4.8	0.6	-2.2	-1.1
Ever taken oral contraceptive pill	1.8	2.0	4.4	1.2	-0.5	-2.1
Supplements: Zinc	1.7	1.9	2.3	-1.5	1.2	1.4
Asthma	1.7	3.3	5.2	-0.7	-2.3	-2.1
Ever had prostate specific antigen (PSA) test	1.7	2.0	4.0	1.1	2.0	0.9
Hypothyroidism (self reported)	1.6	3.7	6.4	2.5	2.2	0.1
Number of treatments/medications taken	1.6	2.8	5.1	-0.1	-1.8	-2.3
Asthma (self-reported)	1.6	3.3	5.6	-0.6	-2.4	-2.0
Rheumatoid Arthritis	1.4	1.9	3.1	1.8	1.4	0.8
Qualifications: CSEs or equivalent	1.4	1.9	2.7	-1.2	-1.6	-1.2
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.0	2.0	0.8	0.4
Diabetes (father)	1.3	1.6	4.3	0.3	-2.1	-0.6
Diabetes (mother)	1.3	1.7	3.7	-0.4	-1.9	-1.1
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	1.8	1.3	1.3	1.1
Serious illness, injury or assault to yourself	1.3	1.6	4.2	0.7	2.0	0.2
Past tobacco smoking	1.3	2.4	5.0	-2.2	-1.5	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	2.7	-1.6	-1.0	-1.6
Illnesses of father: Heart disease	1.3	1.7	5.2	0.1	-0.1	2.3
Commuting to job workplace: Walk	1.3	1.4	3.0	-1.7	-0.7	-0.7
Townsend deprivation index at recruitment	1.2	1.7	2.5	-1.2	-1.0	-1.6
Taking other prescription medications	1.2	1.9	2.9	1.7	-0.1	-1.6
Medication: Simvastatin	1.2	1.7	2.4	-1.4	-0.8	-1.6
Medication: Ventolin 100micrograms inhaler	1.2	1.5	4.3	-0.4	-2.1	-0.2
Medication: Allopurinol	1.2	1.6	3.0	-0.8	-1.0	-1.7
Ever had bowel cancer screening	1.2	1.4	3.6	0.0	0.7	1.9
Breast cancer (self-reported)	1.2	1.5	2.6	-0.4	-1.3	-1.6
Illnesses of father: None of the above (group 1)	1.2	1.5	3.7	0.8	0.3	-1.9
Hearing aid user	1.2	1.4	2.9	1.0	1.7	-0.5
Diastolic blood pressure, automated reading	1.2	3.9	9.9	0.7	-1.1	-3.1
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	2.2	0.0	-1.4	-1.5
Age at First Birth	1.1	1.6	3.7	-1.0	-1.9	-0.4
LDL Cholesterol	1.1	1.7	5.0	-0.0	0.2	2.2
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	2.8	1.0	1.7	0.7
Breastfed as a baby	1.1	1.4	2.3	1.5	1.3	-0.6
Shortness of breath walking on level ground	1.1	1.3	1.7	1.2	1.3	0.9
Knee pain experienced in last month	1.1	1.7	4.1	-0.5	2.0	0.8
Mineral and other dietary supplements	1.1	1.5	3.7	-0.6	-1.9	-0.7
Heart disease (siblings)	1.1	1.4	2.2	1.4	0.3	1.5
Respiratory disease	1.0	2.2	4.3	-0.2	-2.1	-1.5
Pain all over the body in last month	1.0	1.1	2.8	1.7	-0.1	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	1.5	1.1	0.9	-1.2
Migraine (self-reported)	1.0	1.3	1.7	0.9	1.3	1.2
Medication: Omeprazole	1.0	1.2	2.2	-0.2	-1.2	-1.5
Medication: Seretide 50 evohaler	1.0	1.1	2.6	-0.3	-0.8	-1.6
Illnesses of siblings: Diabetes	1.0	1.2	2.4	-0.7	-1.6	-0.8
Financial situation satisfaction	1.0	1.2	1.9	-0.9	-1.4	-0.9
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.5	0.9	1.6	0.8
Bipolar Disorder or Schizophrenia	0.9	2.1	3.0	-1.3	1.3	1.7
Depression (Nagel 2018)	0.9	1.3	3.2	-0.4	-0.8	-1.8
Smoking Status	0.9	2.3	3.6	1.7	0.5	-1.9
Fed-up feelings	0.9	1.7	2.6	-0.8	-1.6	-1.4
Medication: Levothyroxine sodium	0.9	1.5	3.1	1.8	1.2	-0.2
Father’s age at death	0.9	1.3	2.0	1.3	1.4	-0.4
Health satisfaction	0.9	1.2	2.4	-0.6	-1.5	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.4	0.8	1.6	-0.6
Smoking status: Previous	0.9	1.4	2.9	1.7	1.0	0.5
Medication: Gliclazide	0.9	1.0	1.7	1.3	0.4	-1.0
Eye problems/disorders: Glaucoma	0.9	1.0	2.6	-0.5	-0.5	1.6
Myopia	0.9	1.3	2.8	0.9	0.6	1.7
Irritable Bowel Disease (IBD)	0.8	1.9	4.4	-1.2	-2.1	0.1
Primary Biliary Cirrhosis	0.8	1.1	2.8	-0.6	-1.7	-0.4
Medication: Metformin	0.8	1.1	1.9	1.4	-0.6	-1.0
Supplements: Glucosamine	0.8	1.1	1.5	1.2	0.9	1.0
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.4	-1.2	-1.1	0.5
Had other major operations	0.8	1.0	1.6	0.9	1.3	-0.8
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	1.5	-0.6	1.2	1.0
Allergy	0.8	1.9	3.3	0.7	1.4	1.8
Worrier / anxious feelings	0.8	1.5	4.4	0.5	2.1	-0.1
Medication: Lansoprazole	0.8	0.9	1.4	0.3	-1.1	-1.2
Peak expiratory flow (PEF)	0.8	1.8	4.3	-0.8	-0.7	-2.1
High blood pressure (siblings)	0.8	1.2	3.1	-0.1	-0.6	-1.8
Number of full brothers	0.8	1.0	1.6	-1.0	-1.3	-0.6
Worry too long after embarrassment	0.8	1.3	2.2	-1.5	-0.6	-1.1
Eye problems/disorders: None of the above	0.8	1.0	2.3	-0.1	1.5	0.8
Age at last live birth	0.8	1.2	2.3	-1.5	-0.9	-0.6
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.5	-1.2	-0.8	0.8
Medication: Aspirin	0.8	1.1	1.7	0.2	1.2	1.3
Mother’s age at death	0.8	1.0	2.8	1.7	0.1	0.4
Vascular/heart problems diagnosed by doctor	0.8	2.3	4.0	-2.0	-1.6	-0.5
Bipolar Disorder (2018)	0.7	1.0	1.9	-1.1	0.2	1.4
Schizophrenia (2018)	0.7	1.4	2.3	-0.8	1.5	1.1
Major Depression (MDD)	0.7	0.8	1.3	-1.1	-0.4	1.0
Blood Platelet Count	0.7	8.4	17.8	2.6	0.7	4.2
High blood pressure	0.7	1.8	2.9	1.7	1.4	0.7
Medication: Atenolol	0.7	0.9	1.9	1.4	0.8	0.0
Diabetes (self-reported)	0.7	1.1	2.3	1.5	-0.1	-0.9
Lung cancer (father)	0.7	0.8	1.4	-0.9	0.6	1.2
Illnesses of mother	0.7	0.9	1.7	0.6	1.3	0.8
Gout (self-reported)	0.7	0.9	2.3	0.1	-0.6	-1.5
Mean time to correctly identify matches	0.7	1.4	2.5	1.2	1.6	0.2
Heart disease (mother)	0.7	0.9	1.6	1.3	-0.6	-0.8
Osteoporosis (self-reported)	0.7	0.9	2.0	0.3	1.4	-0.8
Wears glasses or contact lenses	0.7	0.8	1.6	1.3	0.7	0.7
Alcohol drinker status: Never	0.7	0.8	1.9	0.1	-0.7	1.4
Basal cell carcinoma (self-reported)	0.7	0.8	1.0	-1.0	1.0	0.7
Intelligence (Savage-Jansen 2018)	0.6	1.9	3.0	-1.6	-1.7	-0.2
Ulcerative Colitis	0.6	0.9	1.0	-0.8	-0.9	-1.0
Relative age voice broke	0.6	0.9	1.4	-1.0	0.6	-1.2
Hair/balding pattern: Pattern 2	0.6	0.7	1.6	-0.7	-1.3	0.0
Medication: Ramipril	0.6	0.8	2.4	1.5	0.2	0.1
Hair/balding pattern: Pattern 3	0.6	0.9	2.3	0.3	1.5	0.4
Wheeze or whistling in the chest in last year	0.6	1.0	1.7	-0.4	-1.0	-1.3
Emphysema/chronic bronchitis	0.6	0.7	0.8	-0.9	-0.7	-0.9
Medication: Aspirin	0.6	0.8	1.6	0.4	0.7	1.3
Hypertension (Self-reported)	0.6	1.7	2.3	1.5	1.3	1.2
Loneliness, isolation	0.6	0.8	1.4	-0.8	-0.7	-1.2
Number of self-reported non-cancer illnesses	0.6	1.1	1.6	0.7	1.1	-1.3
High cholesterol (Self-reported)	0.6	1.1	2.7	-1.6	-0.4	-0.7
Illnesses of father: High blood pressure	0.6	0.8	1.7	-0.6	-0.5	-1.3
Unable to work because of sickness or disability	0.6	0.8	1.2	-1.1	-0.7	-0.8
Depressed Affect (Nagel 2018)	0.5	1.1	2.0	0.1	-1.1	-1.4
Schizophrenia vs Biploar Disorder	0.5	0.6	1.4	0.6	0.1	-1.2
Crohns Disease (2012)	0.5	0.8	1.5	1.2	0.1	1.0
Tanning	0.5	6.2	7.0	2.2	2.6	2.6
Frequency of depressed mood in last 2 weeks	0.5	0.8	1.7	-0.5	-0.6	-1.3
Sitting height	0.5	3.6	5.0	-1.4	-2.2	-1.9
Alcohol usually taken with meals	0.5	0.8	2.1	1.4	0.4	0.4
Forced vital capacity (FVC)	0.5	2.0	3.5	-1.9	-0.8	-1.4
Financial difficulties in last 2 years	0.5	0.6	1.4	-0.6	0.3	-1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.3	-1.1	-0.6	-0.7
Hip circumference	0.5	2.3	3.5	-0.6	-1.7	-1.9
Falls in the last year	0.5	0.6	1.2	-1.1	-0.7	0.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.2	-1.8	-1.1	-1.1
Medication: Cholesterol lowering	0.5	0.8	1.3	1.0	1.1	0.5
Loud music exposure frequency	0.5	0.6	1.2	-1.1	0.1	0.7
Blood clot in the leg (DVT)	0.5	0.6	1.0	-0.9	1.0	-0.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.7	-0.9	-0.8	-0.7
Number of full sisters	0.5	0.6	1.8	0.0	0.3	-1.4
Qualifications: nursing, teaching	0.5	0.7	2.0	0.4	-0.3	1.4
Number of operations (self-reported)	0.5	0.8	1.9	0.7	1.4	0.1
Risk taking	0.5	0.7	1.1	-0.9	0.3	1.0
Ever depressed for a whole week	0.5	0.6	1.5	0.1	0.5	1.2
Pain experienced in last month	0.5	0.9	2.0	1.4	0.7	0.3
Worry (Nagel 2018)	0.4	0.9	2.6	0.1	1.6	0.5
Alzheimer’s Disease (in father)	0.4	0.4	0.8	0.5	0.5	-0.9
Bipolar Disorder (2011)	0.4	0.4	0.6	-0.6	0.8	0.4
Coronary Artery Disease (CAD)	0.4	0.5	0.8	-0.9	-0.2	0.7
BMI	0.4	2.3	3.8	-0.8	-2.0	-1.5
Lung FVC	0.4	2.2	3.1	-1.8	-0.7	-1.7
Sensitivity / hurt feelings	0.4	0.7	1.4	0.3	-0.7	-1.2
Medication: Co-codamol	0.4	0.5	1.2	-0.1	0.5	1.1
Impedance of leg (right)	0.4	1.7	2.2	1.2	1.2	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.5	-0.7	-0.7	-0.6
Multivitamins +/- minerals	0.4	0.5	1.0	1.0	0.7	0.1
Stomach or abdominal pain in last month	0.4	0.5	0.9	-0.7	-0.9	0.4
Body mass index (BMI)	0.4	1.8	2.9	-0.7	-1.7	-1.4
Impedance of leg (left)	0.4	1.9	2.2	1.3	1.4	1.5
Number of incorrect matches in round	0.4	0.7	0.7	-0.8	0.8	-0.8
Mouth/teeth dental problems	0.4	0.6	1.0	1.0	0.5	0.6
Illnesses of siblings	0.4	0.5	1.4	-1.2	-0.1	-0.4
Mouth/teeth dental problems: Dentures	0.4	0.7	1.7	1.3	0.6	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.1	-1.4	-1.1	-0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.3	-0.2	1.2	-0.0
Medication: Ibuprofen	0.4	0.5	0.9	-0.9	-0.4	-0.6
Alcohol intake frequency.	0.4	0.8	1.9	0.3	-0.7	-1.4
Had major operations	0.4	0.4	0.9	0.3	0.6	0.9
Family relationship satisfaction	0.4	0.5	1.5	0.1	-1.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.2	0.3	-0.2	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.6	-1.2	-0.6	-0.9
Average weekly red wine intake	0.4	0.6	1.4	1.2	0.1	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.0	-0.8	-1.0	0.3
Commuting to job workplace: Public transport	0.4	0.5	1.3	-0.3	1.1	0.1
Irritability	0.4	0.7	1.4	0.8	0.0	1.2
Commuting to job workplace: Cycle	0.4	0.4	1.2	-1.1	0.3	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.5	-0.4	1.2	0.1
Alzheimer’s Disease (in mother)	0.3	0.3	0.4	-0.6	-0.6	0.3
Crohns Disease (2017)	0.3	0.6	1.6	0.3	-0.5	1.3
Ovarian Cancer	0.3	0.4	0.7	-0.4	0.8	0.5
Fasting Glucose	0.3	0.3	0.7	-0.5	-0.1	0.8
HbA1C	0.3	0.3	0.6	-0.8	-0.4	-0.1
HDL Cholesterol	0.3	0.4	0.7	-0.2	0.9	0.7
Lupus	0.3	0.5	1.3	-0.2	-0.1	1.1
Neuroticism (2016)	0.3	0.5	0.7	0.4	0.8	0.8
Schizophrenia (2014)	0.3	0.7	1.8	-0.5	1.3	0.4
Blood Eosinophil Count	0.3	2.0	3.2	1.8	1.5	0.7
Height	0.3	6.1	11.4	1.9	3.4	1.9
Relative age of first facial hair	0.3	0.6	1.3	-0.4	0.4	-1.2
Systolic blood pressure, automated reading	0.3	0.8	1.3	1.1	0.8	0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.9	0.2	-0.2
Medication for hormone replacement therapy	0.3	0.4	0.6	0.6	0.8	0.3
Leg fat-free mass (left)	0.3	1.6	2.3	-0.4	-1.5	-1.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.8	0.1	0.9	0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	0.5	0.4	0.5	0.7
Leg predicted mass (left)	0.3	1.6	2.4	-0.4	-1.5	-1.5
Hearing difficulty/problems with background noise	0.3	0.4	0.7	0.3	0.7	-0.8
Heart attack	0.3	0.4	1.0	0.3	-0.1	-1.0
Fluid intelligence score	0.3	0.7	1.7	1.3	0.4	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.9	-0.6	-0.4
Number of live births	0.3	0.4	1.1	0.4	0.3	-1.0
Exposure to tobacco smoke at home	0.3	0.3	0.7	-0.2	-0.3	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.1	0.1	-0.3	-1.1
Pulse wave reflection index	0.3	0.4	0.6	-0.5	-0.6	-0.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.9	0.2	0.4	1.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.8	-0.9	-0.4	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.5	0.8	0.5	0.5	-0.9
Qualifications: College or University degree	0.3	1.1	1.7	-1.3	0.3	1.2
Suffer from ‘nerves’	0.3	0.5	1.2	-0.3	1.1	0.5
Overall health rating	0.3	0.7	1.0	-1.0	-0.3	-1.0
Chest pain or discomfort	0.3	0.5	0.9	0.6	-1.0	-0.3
Leg fat-free mass (right)	0.3	1.5	2.4	-0.4	-1.4	-1.6
Mood swings	0.3	0.5	0.9	0.5	-1.0	-0.5
Diabetes diagnosed by doctor	0.3	0.4	1.1	1.0	0.0	-0.5
Osteoarthritis (self-reported)	0.3	0.3	0.8	0.4	0.1	0.9
Leg predicted mass (right)	0.3	1.6	2.5	-0.4	-1.4	-1.6
Average weekly beer plus cider intake	0.3	0.4	1.1	-1.0	-0.5	-0.2
Fractured/broken bones in last 5 years	0.3	0.4	0.6	-0.6	-0.6	-0.8
Impedance of whole body	0.3	1.3	1.8	1.0	1.4	1.1
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.4	-0.2	-0.8
Mean Putamen Volume	0.2	0.2	0.5	0.3	-0.7	0.4
Triglycerides	0.2	0.3	0.5	0.6	-0.0	0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.4	0.2	-0.6	0.3
Blood White Count	0.2	1.4	2.8	0.7	1.0	1.7
Waist Hip Ratio (WHR)	0.2	1.0	3.0	0.3	0.2	1.7
Allergy or Eczema	0.2	0.5	0.6	-0.8	-0.5	-0.8
Hand grip strength (left)	0.2	0.5	0.7	-0.8	-0.4	-0.8
Hearing difficulty/problems: Yes	0.2	0.3	0.5	-0.1	0.7	0.6
Ever had hysterectomy (womb removed)	0.2	0.3	0.8	-0.1	0.0	0.9
Current tobacco smoking	0.2	0.2	0.7	-0.2	-0.2	-0.8
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.6	-0.6	-0.6	-0.8
Nervous feelings	0.2	0.3	0.5	-0.5	0.7	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.6	0.1	0.8	0.7
Qualifications: None of the above	0.2	0.5	0.7	0.7	0.6	0.8
Weight	0.2	1.2	2.0	-0.2	-1.3	-1.4
Impedance of arm (right)	0.2	1.2	2.0	0.8	1.4	0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.9	-0.4	0.5	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.4	-0.6	-0.5	-0.4
Depression (self-reported)	0.2	0.3	0.8	0.2	-0.9	0.2
Impedance of arm (left)	0.2	0.9	1.9	0.7	1.4	0.6
Arm fat mass (right)	0.2	0.8	1.4	0.2	-0.9	-1.2
Tense / ‘highly strung’	0.2	0.3	0.4	-0.6	0.6	-0.1
Hair/balding pattern: Pattern 4	0.2	0.4	0.9	0.6	-0.1	-1.0
Forced vital capacity (FVC), Best measure	0.2	0.7	1.4	-1.2	-0.6	-0.6
Arm fat-free mass (right)	0.2	0.8	1.3	-0.1	-1.1	-1.0
Exposure to tobacco smoke outside home	0.2	0.3	0.5	0.0	-0.7	0.6
Comparative body size at age 10	0.2	0.6	1.0	-0.7	0.5	-1.0
Number of children fathered	0.2	0.3	0.4	-0.6	0.3	0.6
Medication: Blood pressure	0.2	0.4	1.1	1.0	-0.0	-0.2
Arm fat percentage (left)	0.2	0.6	1.0	0.0	-1.0	-1.0
Long-standing illness, disability or infirmity	0.2	0.3	0.7	0.2	0.2	-0.8
Back pain experienced in last month	0.2	0.3	0.4	-0.3	-0.5	-0.6
Smoking status: Current	0.2	0.2	0.7	0.2	0.0	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.6	-0.7	-0.5	-0.4
Arm fat mass (left)	0.2	0.8	1.6	0.2	-0.9	-1.3
Miserableness	0.2	0.4	0.8	-0.3	-0.6	-0.9
Basal metabolic rate	0.2	1.1	1.7	-0.2	-1.3	-1.3
Supplements: Calcium	0.2	0.3	0.6	-0.4	-0.0	-0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	0.3	0.0	-0.9
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.1	0.8	0.4
Neuroticism (Nagel 2018)	0.1	0.1	0.2	0.0	-0.4	-0.5
Reaction Time	0.1	0.2	0.4	0.0	0.2	-0.7
Breast Cancer	0.1	0.1	0.2	-0.5	-0.3	0.2
Prostate Cancer	0.1	0.1	0.2	-0.4	0.3	0.4
Heel T-Score	0.1	0.5	1.2	-0.4	-0.2	1.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.6	-0.5	0.1
Lung FEV1/FVC ratio	0.1	0.5	0.8	0.9	-0.7	0.0
Vitamin and mineral supplements	0.1	0.2	0.2	-0.4	-0.4	0.5
Trunk fat percentage	0.1	0.5	1.2	1.1	-0.2	-0.5
Hand grip strength (right)	0.1	0.2	0.5	-0.1	-0.3	-0.7
Trunk fat mass	0.1	0.5	1.1	1.1	-0.4	-0.6
Waist circumference	0.1	0.4	1.0	0.2	-1.0	-0.1
Neuroticism score	0.1	0.2	0.4	-0.1	0.4	-0.6
Arm fat percentage (right)	0.1	0.6	1.0	0.1	-1.0	-0.8
Trunk fat-free mass	0.1	0.4	0.6	0.0	-0.8	-0.8
Time employed in main current job	0.1	0.1	0.2	-0.0	-0.0	-0.4
Happiness	0.1	0.1	0.3	-0.3	-0.5	-0.0
Trunk predicted mass	0.1	0.4	0.7	-0.0	-0.8	-0.8
Standing height	0.1	0.9	1.6	1.3	1.0	0.1
Length of working week for main job	0.1	0.1	0.1	-0.3	0.2	0.2
Birth weight of first child	0.1	0.2	0.6	0.1	0.1	-0.8
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.5	-0.5	-0.1	0.7
Headache pain in last month	0.1	0.2	0.5	-0.7	-0.1	-0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.3	-0.3	-0.1	0.6
Glaucoma (self-reported)	0.1	0.1	0.1	-0.3	0.1	0.3
Medication: Amlodipine	0.1	0.1	0.1	-0.3	0.1	0.3
Body fat percentage	0.1	0.5	1.0	1.0	-0.6	-0.4
Leg fat percentage (right)	0.1	0.2	0.4	0.3	-0.7	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.1	-0.5	-0.2
Age at first live birth	0.1	0.2	0.5	-0.7	0.4	0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	-0.3	-0.5	-0.3
Neck or shoulder pain in last month	0.1	0.2	0.5	-0.7	-0.3	-0.1
Whole body fat mass	0.1	0.6	0.8	0.8	-0.6	-0.9
Leg fat mass (right)	0.1	0.5	0.8	0.3	-0.8	-0.9
Arm predicted mass (right)	0.1	0.6	0.8	0.4	-0.9	-0.9
Comparative height size at age 10	0.1	0.7	1.4	1.2	-0.1	0.8
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	0.3	-0.1	-0.4
Supplements: Vitamin C	0.1	0.2	0.3	-0.5	-0.3	-0.4
Whole body fat-free mass	0.1	0.7	1.2	-0.1	-1.1	-0.9
Whole body water mass	0.1	0.8	1.3	-0.2	-1.1	-1.0
Average weekly champagne plus white wine intake	0.1	0.2	0.3	0.5	-0.1	-0.5
Guilty feelings	0.1	0.1	0.2	0.1	0.5	0.4
Medication: Bendroflumethiazide	0.1	0.1	0.1	0.4	-0.1	0.3
Medication: Paracetamol	0.1	0.2	0.3	-0.5	-0.4	0.3
Medication: Lisinopril	0.1	0.1	0.3	0.1	-0.2	-0.6
Leg fat percentage (left)	0.1	0.2	0.2	0.5	-0.5	-0.3
Arm fat-free mass (left)	0.1	0.6	1.1	0.2	-1.0	-0.8
Leg fat mass (left)	0.1	0.6	0.9	0.4	-0.8	-0.9
Arm predicted mass (left)	0.1	0.5	0.9	0.2	-0.9	-0.9
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	0.4	-0.2	0.4
Systolic Blood Pressure	0.0	0.1	0.1	0.3	-0.1	-0.3
Cardiovascular Disease	0.0	0.1	0.3	0.1	-0.1	0.6
Neuroticism	0.0	0.1	0.3	0.1	0.0	-0.5
Hair Pigment	0.0	0.6	1.6	-0.2	-1.2	0.3
Average weekly spirits intake	0.0	0.0	0.1	-0.2	-0.2	-0.3
Angina	0.0	0.0	0.1	0.1	-0.1	0.2
Severe depression (siblings)	0.0	0.0	0.1	0.3	0.0	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.1	0.1	0.1	0.3
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.0	-0.3	-0.2
Medication: Paracetamol	0.0	0.1	0.1	-0.3	-0.3	0.0
Birth weight	0.0	0.1	0.1	-0.1	0.2	-0.3
Angina (self-reported)	0.0	0.0	0.0	-0.0	-0.2	-0.2
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.1	0.1	0.2
Friendships satisfaction	0.0	0.0	0.0	-0.2	-0.0	0.0
Medication for cholesterol	0.0	0.0	0.1	-0.1	0.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	-0.2	0.0	0.1
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	-0.0	-0.1	0.3
Medication: Blood pressure	0.0	0.0	0.1	0.2	0.3	0.1

Hub : Genes

CRABP1

Models

Trait associations