TWAS hub - CSF2RB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Sigmoid	0.3680	0.1020	0.00320	-0.006	NA	-0.008	NA	-0.005	5.8e-01	NA	0.79000	NA	5.2e-01
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0404	0.0164	0.00024	0.038	0.033	0.029	NA	0.035	3.7e-05	0.00012	0.00029	NA	8.1e-05
3	TCGA	Lung Adenocarcinoma	0.0299	0.0155	0.00980	0.006	0.008	0.001	NA	0.005	5.7e-02	0.03300	0.22000	NA	7.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Allergy	4.7	10.9	26.7	1.0	5.2	2.2
Crohns Disease (2017)	4.4	9.8	15.6	-0.5	-3.9	-3.7
Crohns Disease (2012)	4.1	6.6	11.9	1.3	-3.5	-2.4
Hayfever/allergic rhinitis (self-reported)	3.8	5.0	12.8	-1.1	-1.0	-3.6
Hayfever, allergic rhinitis or eczema	3.7	8.1	21.0	0.7	-4.6	-1.6
Coronary Artery Disease (CAD)	3.3	3.9	7.6	1.4	-2.8	-1.6
Allergy or Eczema	3.1	8.2	24.0	-0.5	-4.9	-0.6
Diverticular disease/diverticulitis (self-reported)	3.1	3.7	7.9	0.6	2.8	1.7
Rheumatoid Arthritis	3.0	4.1	11.8	0.7	-3.4	0.4
Medication for pain relief, constipation, heartburn	2.9	4.9	13.0	-3.6	-1.2	0.6
Ulcerative Colitis	2.7	4.0	8.0	-1.2	1.6	2.8
Sensitivity / hurt feelings	2.6	4.5	8.9	-3.0	0.5	-2.1
Commuting to job workplace: Cycle	2.6	3.2	6.1	1.3	2.5	1.3
Diabetes (father)	2.4	3.0	4.4	0.7	2.1	2.1
Respiratory disease	2.3	5.0	10.5	-0.8	-3.2	-2.0
Ever used hormone-replacement therapy (HRT)	2.3	2.9	4.6	-1.4	1.5	2.1
Alcohol intake versus 10 years previously	2.3	3.5	5.3	-2.3	-0.9	-2.1
Medication: Ibuprofen (e.g. Nurofen)	2.3	2.9	5.2	2.3	1.8	-0.3
Pulse wave reflection index	2.3	2.9	3.6	1.9	1.8	1.3
Asthma	2.2	4.3	9.7	-0.4	-3.1	-1.8
Number of full brothers	2.2	2.7	6.9	1.1	2.6	0.4
Miserableness	2.2	3.9	5.8	-0.7	2.3	-2.4
Medication: Simvastatin	2.1	3.0	9.0	0.0	-3.0	-0.3
Had major operations	2.1	2.4	3.4	1.8	-1.0	-1.7
Asthma (self-reported)	2.1	4.2	9.6	-0.2	-3.1	-1.8
Mother’s age at death	2.1	2.6	4.8	2.2	-1.6	-0.8
Medication: Lansoprazole	2.0	2.3	3.3	-1.8	-1.5	-1.1
Medication: Paracetamol	2.0	3.3	9.6	3.1	0.3	0.3
Frequency of depressed mood in last 2 weeks	1.9	2.7	7.0	-1.0	2.6	-0.1
Ever highly irritable/argumentative for 2 days	1.9	2.3	6.2	-0.6	2.5	0.4
Medication: Seretide 50 evohaler	1.9	2.2	6.2	0.7	0.2	2.5
Illness, injury, bereavement, stress in last 2 years	1.9	2.4	4.7	-0.9	-1.3	-2.2
Mouth/teeth dental problems: Dentures	1.8	3.0	8.2	0.5	-0.7	2.9
Medication: Aspirin	1.8	2.4	6.3	2.5	0.9	0.2
Diabetes (mother)	1.7	2.1	5.6	-2.4	-0.7	0.5
Hair/balding pattern: Pattern 2	1.7	2.2	2.9	-1.2	-1.7	-1.5
Medication for cholesterol, blood pressure or diabetes	1.7	2.9	5.7	-2.4	1.7	-0.2
Medication: Ibuprofen	1.7	2.1	4.0	2.0	1.5	-0.1
Myopia	1.7	2.5	6.9	0.1	-0.8	-2.6
Medication for hormone replacement therapy	1.6	1.8	3.7	-0.4	1.3	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	3.2	-1.6	1.8	0.2
Family relationship satisfaction	1.6	2.0	3.6	1.9	1.2	-1.0
High cholesterol (Self-reported)	1.6	2.9	7.1	1.0	-2.7	-0.7
Mean Putamen Volume	1.5	1.8	5.1	-0.0	0.4	2.3
HbA1C	1.5	1.7	2.0	-1.1	-1.4	-1.4
Maternal smoking around birth	1.5	2.1	4.7	-1.2	0.4	2.2
Medication: Blood pressure	1.5	2.6	3.8	2.0	-1.7	0.9
Supplements: Vitamin C	1.5	1.7	3.5	0.9	1.0	1.9
Number of self-reported non-cancer illnesses	1.5	2.6	4.7	0.4	-1.7	-2.2
Alzheimer’s Disease (in mother)	1.4	1.6	4.4	2.1	0.6	0.2
Alzheimer’s Disease (including proxy)	1.4	2.1	6.1	2.5	-0.4	-0.1
Medication: Metformin	1.4	2.0	3.9	2.0	1.4	0.5
Supplements: Glucosamine	1.4	1.8	3.1	1.4	0.7	1.8
Medication: Cholesterol lowering	1.4	2.1	4.1	1.5	-2.0	0.3
Loneliness, isolation	1.4	1.9	4.2	1.0	2.1	-0.8
Number of treatments/medications taken	1.3	2.2	5.5	2.3	-1.1	-0.1
Neuroticism score	1.3	2.7	6.7	-0.5	1.2	-2.6
Father’s age at death	1.3	1.7	2.9	0.1	-1.7	-1.5
Medication: Omeprazole	1.3	1.6	2.8	-1.4	-0.2	-1.7
Medication: Paracetamol	1.3	1.9	5.6	2.4	0.1	0.5
Alcohol drinker status: Never	1.3	1.6	2.8	-1.7	-1.0	0.9
Depression (Nagel 2018)	1.2	1.8	5.0	-0.5	2.2	0.2
Average weekly fortified wine intake	1.2	1.4	2.4	1.5	-1.3	0.5
Pain all over the body in last month	1.2	1.2	2.0	-1.3	1.4	-0.3
Worry too long after embarrassment	1.2	2.0	4.9	-0.8	0.6	-2.2
Emphysema/chronic bronchitis	1.2	1.4	3.2	-0.9	-0.5	-1.8
Friendships satisfaction	1.2	1.4	1.6	1.3	-1.1	-1.2
Osteoarthritis (self-reported)	1.2	1.5	4.0	0.4	-0.6	2.0
Schizophrenia (2018)	1.1	2.2	6.6	-0.1	-2.6	0.2
Lupus	1.1	1.6	3.5	1.0	-0.5	-1.9
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	4.3	0.7	2.1	0.5
Loud music exposure frequency	1.1	1.2	3.5	-0.3	1.9	0.2
Medication: Ventolin 100micrograms inhaler	1.1	1.4	2.2	0.8	-1.5	-1.1
Eye problems/disorders: None of the above	1.1	1.3	2.3	1.5	-1.2	-0.4
Leg pain on walking	1.1	1.4	3.4	-0.9	1.8	0.1
Pain type(s) experienced in last month: Hip pain	1.1	1.4	2.3	0.7	1.5	1.2
Irritability	1.1	1.9	2.1	-1.3	1.5	-1.4
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.6	0.7	-1.0	-1.6
Basal cell carcinoma (self-reported)	1.1	1.3	2.3	0.4	-1.2	1.5
Irritable Bowel Disease (IBD)	1.0	2.5	4.4	-0.1	-2.1	-1.7
Body Mass Index (BMI) (2010)	1.0	1.4	2.8	-0.7	1.0	1.7
Severe depression (siblings)	1.0	1.1	1.8	-1.3	-0.0	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	4.1	-0.2	2.0	0.3
Hair/balding pattern: Pattern 3	1.0	1.5	3.5	0.7	-0.8	1.9
Length of working week for main job	1.0	1.1	1.9	0.8	0.8	-1.4
Exposure to tobacco smoke at home	1.0	1.1	2.2	-0.9	0.6	1.5
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.8	-0.9	0.4	-1.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.1	-1.5	1.2	-0.2
Mean time to correctly identify matches	1.0	1.9	4.6	-0.9	-2.1	-0.5
Medication: Aspirin	1.0	1.3	3.5	1.9	0.5	0.3
Average weekly beer plus cider intake	1.0	1.4	3.4	1.9	0.7	-0.5
Cholesterol lowering medication	1.0	1.5	2.8	-0.1	-1.7	-1.3
Alzheimer’s Disease (in father)	0.9	1.0	2.8	-0.1	0.5	1.7
Major Depression (MDD)	0.9	1.1	2.2	0.9	1.5	-0.5
HDL Cholesterol	0.9	1.5	4.1	0.6	2.0	-0.2
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.6	-1.3	0.9	0.7
Blood Red Count	0.9	8.3	23.8	-0.9	4.9	-0.5
Supplements: Zinc	0.9	1.0	1.6	1.3	0.9	0.8
Medication: Co-codamol	0.9	1.0	1.8	1.1	-1.3	0.4
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.3	-1.5	0.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.6	1.3	0.2	-1.1
Lung cancer (father)	0.9	1.0	2.7	0.1	1.6	-0.6
Medication: Amlodipine	0.9	1.3	2.1	1.4	-1.1	-0.7
Number of children fathered	0.9	1.1	3.2	0.2	0.1	1.8
Neck or shoulder pain in last month	0.9	1.3	2.3	1.5	0.0	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.2	1.5	0.6	-0.7
Mineral and other dietary supplements	0.9	1.2	3.6	-1.9	-0.1	0.0
Guilty feelings	0.9	1.3	3.6	1.9	-0.3	-0.4
Medication: Atorvastatin	0.9	1.2	3.1	1.8	-0.6	0.2
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.9	1.7	0.8	-0.2
Depressed Affect (Nagel 2018)	0.8	1.6	3.1	0.2	1.8	-1.3
Schizophrenia (2014)	0.8	1.8	4.8	-0.3	-2.2	-0.8
Neuroticism	0.8	1.9	4.3	-0.8	1.0	-2.1
Hearing difficulty/problems: Yes	0.8	1.3	1.6	0.8	1.3	1.2
Serious illness, injury or assault to yourself	0.8	1.0	1.9	1.4	0.8	0.7
Multivitamins +/- minerals	0.8	1.1	1.6	0.2	-1.3	-1.2
Alcohol usually taken with meals	0.8	1.3	1.8	1.0	-1.4	-1.1
Heart attack	0.8	1.1	2.5	1.6	0.7	-0.5
Happiness	0.8	0.9	2.0	1.4	0.1	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.1	-0.2	1.8	-0.8
High blood pressure (siblings)	0.8	1.1	2.3	-1.5	-0.4	0.9
Exposure to tobacco smoke outside home	0.8	1.1	2.9	1.7	0.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.1	-1.1	-0.9	0.8
Shortness of breath walking on level ground	0.8	0.9	1.4	-0.3	1.1	1.2
Average weekly red wine intake	0.8	1.2	3.1	1.8	-0.3	-0.7
Mood swings	0.8	1.5	4.2	-0.2	0.5	-2.1
Hearing aid user	0.8	0.9	2.5	0.0	0.3	1.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.9	-1.0	0.1	-1.4
Pain experienced in last month	0.8	1.3	2.7	-0.3	-1.6	-1.0
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.4	2.1	0.8	1.1
Reaction Time	0.7	1.3	2.2	-1.5	-1.1	-0.8
Taking other prescription medications	0.7	1.2	2.0	1.2	-1.4	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	4.0	-2.0	0.3	0.6
Medication: Atenolol	0.7	0.9	1.5	1.2	-0.5	-0.9
Pulse rate	0.7	1.2	2.0	-1.1	-1.4	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.8	0.9	1.3	-0.2
Wheeze or whistling in the chest in last year	0.7	1.2	2.3	-1.5	-1.0	-0.6
Qualifications: nursing, teaching	0.7	1.1	2.7	0.1	0.7	1.6
Financial situation satisfaction	0.7	0.8	1.2	1.1	-0.5	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.1	-1.5	-0.6	0.5
Bipolar Disorder (2018)	0.6	1.0	2.8	-0.3	0.2	-1.7
Bipolar Disorder or Schizophrenia	0.6	1.5	3.6	0.0	-1.9	-0.9
Fasting Glucose	0.6	0.7	1.3	-0.7	0.6	1.1
Blood Eosinophil Count	0.6	4.5	9.9	-1.8	-0.3	-3.1
Hand grip strength (left)	0.6	1.6	1.8	-1.1	1.3	1.3
Qualifications: CSEs or equivalent	0.6	0.8	2.2	1.5	-0.1	-0.5
Chronic bronchitis/emphysema (father)	0.6	0.8	2.1	-1.4	-0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.2	-1.8	-1.0	-0.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.9	0.5	1.4	-0.3
Fluid intelligence score	0.6	1.2	3.2	0.7	-0.1	1.8
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.1	-1.5	1.4	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.8	0.2	1.4	0.6
Depression (self-reported)	0.6	0.7	1.1	1.0	1.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	4.2	1.1	-0.3	-2.0
Headache pain in last month	0.6	1.0	1.4	-0.9	1.0	-1.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.0	-1.4	-0.2	-0.2
Comparative body size at age 10	0.6	1.6	4.4	-0.5	2.1	-0.3
Angina (self-reported)	0.6	0.8	1.5	-0.8	-0.6	-1.2
Alcohol intake frequency.	0.6	1.4	4.0	-2.0	-0.1	0.1
Overall health rating	0.6	1.2	2.1	-1.1	-1.5	-0.5
Age at last live birth	0.6	0.9	2.0	-1.4	-0.2	0.9
Illnesses of father: None of the above (group 1)	0.6	0.8	1.7	-1.3	0.3	-0.8
Commuting to job workplace: Public transport	0.6	0.8	1.2	0.1	-1.0	1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.2	1.5	-0.2	0.3
Illnesses of father: High blood pressure	0.6	0.7	1.9	1.4	0.5	-0.1
Risk taking	0.6	0.8	0.9	0.9	-0.9	-1.0
Prostate Cancer	0.5	0.7	1.9	1.4	-0.2	-0.1
Triglycerides	0.5	0.8	2.2	-0.5	-0.1	1.5
Fed-up feelings	0.5	1.0	2.0	0.5	0.8	-1.4
Mouth/teeth dental problems	0.5	0.7	1.8	0.3	-0.6	-1.4
Diabetes (self-reported)	0.5	0.7	1.0	0.8	-0.7	1.0
Illnesses of siblings	0.5	0.7	1.5	0.6	-0.6	-1.2
Number of live births	0.5	0.7	1.3	0.2	0.9	1.1
Prospective memory result	0.5	0.6	1.6	-1.3	-0.3	-0.3
Pulse wave Arterial Stiffness index	0.5	0.6	0.7	0.6	0.8	-0.9
Hair/balding pattern: Pattern 4	0.5	1.1	2.7	0.7	1.6	0.5
Blood clot in the leg (DVT)	0.5	0.6	1.5	-1.2	-0.4	0.3
Age at first live birth	0.5	0.8	2.1	-1.5	0.3	0.5
Pulse rate, automated reading	0.5	1.6	2.7	-1.4	-1.6	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	0.9	-0.8	-0.3	-1.0
Illnesses of father: Heart disease	0.5	0.7	1.5	1.2	0.5	0.7
Illnesses of siblings: Diabetes	0.5	0.6	1.6	-1.3	-0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.7	1.1	0.2	-1.3
Wears glasses or contact lenses	0.5	0.5	1.5	-1.2	-0.3	0.0
Eye problems/disorders: Glaucoma	0.5	0.6	1.0	0.7	1.0	0.6
Supplements: Calcium	0.5	0.5	0.9	0.9	-0.9	-0.1
Heart disease (siblings)	0.5	0.6	0.9	0.8	0.9	-0.5
Alcohol drinker status: Previous	0.5	0.6	1.4	0.2	-0.6	1.2
Pack years of smoking	0.5	0.7	1.4	0.2	1.2	0.9
Neuroticism (Nagel 2018)	0.4	1.0	2.3	-0.2	1.5	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.0	-1.0	-0.4	0.5
Angina	0.4	0.5	0.8	-0.7	-0.5	-0.9
Vitamin and mineral supplements	0.4	0.6	0.8	-0.5	0.8	0.9
Pack years adult smoking proportion	0.4	0.6	1.1	0.4	1.1	0.7
Hand grip strength (right)	0.4	1.0	2.6	-0.0	1.6	0.5
Townsend deprivation index at recruitment	0.4	0.6	1.2	-0.2	0.8	-1.1
Age when periods started (menarche)	0.4	0.9	1.7	-1.3	-0.7	0.8
High blood pressure	0.4	1.0	2.2	0.8	-1.5	-0.5
High blood pressure (mother)	0.4	0.5	1.6	-0.2	-0.2	-1.2
Nervous feelings	0.4	0.8	1.5	-0.8	1.2	-0.5
Had menopause	0.4	0.5	1.4	-0.3	-0.1	1.2
Qualifications: None of the above	0.4	0.8	2.2	-0.5	-0.2	1.5
Medication: Ramipril	0.4	0.5	1.1	0.7	-1.0	-0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	3.4	0.6	-0.0	-1.9
Illnesses of mother	0.4	0.5	1.0	-0.1	1.0	-0.6
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.2	0.1	-1.1	-0.9
Pulse wave peak to peak time	0.4	0.5	0.7	-0.7	-0.6	0.8
Migraine (self-reported)	0.4	0.5	0.8	0.9	0.7	0.5
Suffer from ‘nerves’	0.4	0.7	1.8	-0.4	1.4	0.2
Knee pain experienced in last month	0.4	0.6	1.5	0.2	0.6	1.2
Smoking status: Previous	0.4	0.5	1.2	-0.5	-0.3	-1.1
Osteoporosis (self-reported)	0.4	0.4	0.6	-0.8	0.8	0.3
Medication: Bendroflumethiazide	0.4	0.5	1.1	-1.1	-0.6	0.4
Ever depressed for a whole week	0.4	0.5	1.1	-0.1	1.0	0.7
Worry (Nagel 2018)	0.3	0.7	1.4	0.8	1.2	-0.2
Ulcerative Colitis (UC)	0.3	0.5	1.0	0.3	0.7	1.0
LDL Cholesterol	0.3	0.4	0.9	-0.6	0.1	-1.0
Waist Hip Ratio (WHR)	0.3	1.3	2.2	1.2	-0.5	-1.5
Smoking Status	0.3	0.6	1.7	-0.3	0.3	-1.3
Average weekly spirits intake	0.3	0.4	0.7	0.4	-0.8	0.6
Systolic blood pressure, automated reading	0.3	1.0	1.7	1.3	-1.1	0.4
Current tobacco smoking	0.3	0.6	1.4	0.3	1.2	-0.4
Past tobacco smoking	0.3	0.5	1.4	0.2	0.2	1.2
Forced vital capacity (FVC)	0.3	1.1	3.1	-0.1	-0.3	-1.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.0	-0.0	1.0	0.6
Falls in the last year	0.3	0.4	1.1	0.1	1.0	0.1
Peak expiratory flow (PEF)	0.3	0.8	1.8	0.2	-0.6	-1.4
Gout (self-reported)	0.3	0.4	0.9	0.2	-1.0	-0.5
Forced vital capacity (FVC), Best measure	0.3	1.2	2.7	0.8	-0.6	-1.6
Health satisfaction	0.3	0.3	0.5	-0.7	-0.6	-0.3
Qualifications: College or University degree	0.3	1.0	2.4	0.2	1.6	-0.7
Number of full sisters	0.3	0.4	1.1	0.4	1.0	0.3
Hypertension (Self-reported)	0.3	0.7	1.9	0.3	-1.4	-0.4
Medication: Gliclazide	0.3	0.3	0.7	0.2	0.4	-0.8
Smoking status: Current	0.3	0.4	1.0	-0.0	1.0	-0.5
Average weekly champagne plus white wine intake	0.3	0.5	1.3	1.1	0.3	0.1
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.7	-0.9	-0.4	-0.4
Medication: Lisinopril	0.3	0.4	0.7	0.8	-0.5	-0.2
Ever smoked	0.3	0.6	1.6	0.0	0.3	-1.3
Age started oral contraceptive pill	0.3	0.4	0.4	-0.6	-0.6	0.6
Unable to work because of sickness or disability	0.3	0.4	1.0	-1.0	0.0	0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.6	0.8	0.9	0.4	0.9
Ovarian Cancer	0.2	0.3	0.7	0.0	-0.3	-0.9
Age at First Birth	0.2	0.3	0.7	0.2	-0.2	0.8
Neuroticism (2016)	0.2	0.3	0.3	-0.5	0.5	-0.6
Blood Platelet Count	0.2	2.9	5.5	-1.3	-1.2	-2.3
Cardiovascular Disease	0.2	0.7	1.8	0.2	-0.6	-1.3
Lung FEV1/FVC ratio	0.2	1.0	2.5	1.6	0.4	-0.6
Lung FVC	0.2	1.1	3.3	-0.2	-1.8	0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.7	0.9	-0.2	0.3
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	-0.8	0.2	-0.3
Relative age voice broke	0.2	0.3	0.7	0.4	-0.8	-0.3
Hearing difficulty/problems with background noise	0.2	0.3	0.4	-0.6	0.6	0.5
Trunk fat-free mass	0.2	1.1	3.3	0.1	-0.4	-1.8
Trunk predicted mass	0.2	1.1	3.1	0.0	-0.4	-1.7
Glaucoma (self-reported)	0.2	0.2	0.4	0.6	0.6	0.2
Birth weight	0.2	0.4	0.6	0.6	-0.7	-0.5
Leg fat percentage (right)	0.2	0.6	1.0	0.3	1.0	0.8
Heart disease (mother)	0.2	0.2	0.3	0.5	-0.6	0.3
Ever had bowel cancer screening	0.2	0.2	0.3	-0.6	-0.5	0.4
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.8	-0.5	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.6	0.2	-0.8	0.1
Eye problems/disorders: Cataract	0.2	0.2	0.5	-0.7	-0.2	0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	-1.0	-0.0	0.1
Medication for cholesterol	0.2	0.3	0.8	-0.9	0.4	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.7	-0.3	0.3	-0.8
Whole body water mass	0.2	0.9	2.6	0.0	-0.1	-1.6
Arm fat mass (left)	0.2	0.6	1.4	-0.3	0.6	-1.2
Arm fat-free mass (left)	0.2	0.8	2.2	0.3	0.3	-1.5
Number of operations (self-reported)	0.2	0.2	0.5	0.4	0.7	-0.3
Diastolic blood pressure, automated reading	0.2	0.7	0.9	0.7	0.9	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.5	-0.5	1.2	0.5
Arm predicted mass (left)	0.2	0.9	2.3	0.3	0.3	-1.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	0.4	-0.2	0.1
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.4	-0.5	-0.1
Blood White Count	0.1	0.6	1.4	-1.2	0.6	-0.2
BMI	0.1	0.4	0.7	0.4	0.8	-0.6
Systolic Blood Pressure	0.1	0.3	0.6	0.5	0.1	-0.8
Hypothyroidism (self reported)	0.1	0.3	0.7	-0.1	0.9	-0.3
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	0.8	0.1	-0.3
Chronotype (morning person)	0.1	0.2	0.3	0.4	-0.5	0.3
Impedance of leg (right)	0.1	0.3	0.6	0.5	0.8	0.5
Leg fat-free mass (left)	0.1	0.6	1.6	0.1	0.3	-1.3
Stomach or abdominal pain in last month	0.1	0.2	0.2	-0.5	0.5	-0.1
Impedance of leg (left)	0.1	0.3	0.8	-0.1	0.5	0.9
Leg predicted mass (left)	0.1	0.6	1.6	0.1	0.3	-1.3
Waist circumference	0.1	0.4	1.0	0.1	0.3	-1.0
Number of incorrect matches in round	0.1	0.1	0.3	-0.2	-0.6	-0.1
Had other major operations	0.1	0.1	0.1	0.3	0.3	0.2
Financial difficulties in last 2 years	0.1	0.1	0.2	-0.4	0.2	-0.1
Weight	0.1	0.4	0.7	-0.3	0.5	-0.8
Impedance of arm (right)	0.1	0.4	0.8	-0.9	-0.7	-0.3
Arm fat percentage (right)	0.1	0.3	0.6	-0.4	0.5	-0.7
Hip circumference	0.1	0.3	0.6	-0.3	0.3	-0.8
Worrier / anxious feelings	0.1	0.2	0.7	-0.0	0.8	-0.2
Noisy workplace	0.1	0.1	0.2	0.1	0.4	-0.4
Impedance of arm (left)	0.1	0.4	0.8	-0.4	-0.9	-0.4
Arm fat mass (right)	0.1	0.6	1.0	-0.2	0.8	-1.0
Standing height	0.1	1.4	3.7	0.1	-0.6	-1.9
Tense / ‘highly strung’	0.1	0.1	0.3	-0.5	0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.5	0.5	-0.1
Arm fat-free mass (right)	0.1	0.4	1.1	0.5	0.2	-1.0
Medication: Allopurinol	0.1	0.2	0.3	-0.2	-0.5	0.6
Whole body fat mass	0.1	0.3	0.6	0.1	0.8	-0.4
Leg fat mass (right)	0.1	0.6	1.5	0.1	1.2	0.4
Arm predicted mass (right)	0.1	0.5	1.0	0.7	0.2	-1.0
Chest pain or discomfort	0.1	0.1	0.3	-0.1	-0.5	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.4	-0.3	-0.1
Whole body fat-free mass	0.1	0.8	2.4	0.1	-0.1	-1.6
Leg fat-free mass (right)	0.1	0.4	1.3	-0.1	0.2	-1.1
Arm fat percentage (left)	0.1	0.3	0.5	-0.3	0.4	-0.7
Long-standing illness, disability or infirmity	0.1	0.2	0.6	0.2	-0.8	0.1
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.4	-0.1	0.2
Back pain experienced in last month	0.1	0.2	0.3	-0.3	-0.6	-0.5
Breast cancer (self-reported)	0.1	0.1	0.3	-0.1	-0.5	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.2	-0.5	0.3	-0.3
Leg predicted mass (right)	0.1	0.4	1.3	-0.1	0.2	-1.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.2	0.3	-0.4
Medication: Blood pressure	0.1	0.3	0.4	0.3	-0.6	-0.6
Basal metabolic rate	0.1	0.8	2.4	-0.0	0.2	-1.5
Leg fat percentage (left)	0.1	0.4	0.7	-0.1	0.6	0.9
Fractured/broken bones in last 5 years	0.1	0.1	0.4	-0.6	-0.0	-0.3
Leg fat mass (left)	0.1	0.3	0.9	0.0	1.0	0.3
Breast Cancer	0.0	0.1	0.1	0.3	-0.1	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.1	0.3	-0.5	0.2	-0.0
Height	0.0	0.6	1.9	-1.4	-0.0	0.1
Hair Pigment	0.0	1.4	2.6	1.6	-0.0	1.2
Tanning	0.0	0.4	1.3	0.1	-0.0	1.1
Relative age of first facial hair	0.0	0.0	0.1	0.2	0.1	-0.3
Trunk fat percentage	0.0	0.1	0.3	0.1	0.6	-0.3
Medication: Levothyroxine sodium	0.0	0.0	0.0	-0.2	-0.0	-0.2
Sitting height	0.0	0.1	0.2	0.3	0.4	-0.4
Body mass index (BMI)	0.0	0.2	0.6	-0.2	0.7	-0.1
Trunk fat mass	0.0	0.2	0.4	0.2	0.4	-0.7
Time employed in main current job	0.0	0.0	0.1	-0.1	-0.0	0.3
Breastfed as a baby	0.0	0.0	0.0	0.1	0.0	0.1
Birth weight of first child	0.0	0.0	0.0	0.1	0.2	0.0
Body fat percentage	0.0	0.1	0.4	0.1	0.6	0.0
Comparative height size at age 10	0.0	0.1	0.3	-0.2	-0.1	-0.6
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	0.0	0.3	0.2
Impedance of whole body	0.0	0.0	0.0	-0.1	-0.2	0.1

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