TWAS hub - CWC27

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.074	0.028	4.8e-04	0.034	0.022	0.029	0.028	0.031	4.8e-05	0.00087	1.8e-04	2e-04	9.4e-05
2	GTEx	Testis	0.179	0.051	1.6e-05	0.191	NA	0.203	NA	0.199	6.9e-09	NA	2.1e-09	NA	3.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Illnesses of father: None of the above (group 1)	8.1	10.0	10.5	-3.2	3.1
Sensitivity / hurt feelings	7.5	12.9	13.0	3.6	-3.6
Neuroticism (Nagel 2018)	6.5	15.3	15.4	3.9	-3.9
Tense / ‘highly strung’	6.3	10.5	10.6	3.2	-3.2
Leg pain on walking	6.3	7.9	8.2	2.9	-2.8
Guilty feelings	6.2	9.3	9.6	3.1	-3.0
Loneliness, isolation	5.7	7.9	9.1	3.0	-2.6
Frequency of depressed mood in last 2 weeks	5.5	7.7	8.4	2.9	-2.7
Chronotype (morning person)	5.4	12.4	12.6	-3.5	3.5
Financial difficulties in last 2 years	5.1	6.9	7.3	2.7	-2.5
Health satisfaction	4.9	6.4	6.7	2.6	-2.4
Alcohol usually taken with meals	4.8	7.8	7.9	-2.8	2.8
Pain experienced in last month	4.8	8.1	8.4	-2.9	2.8
BMI	4.7	27.4	28.0	5.2	-5.3
Risk taking	4.4	6.4	6.7	2.6	-2.5
Nervous feelings	4.3	7.9	8.5	2.9	-2.7
Hair/balding pattern: Pattern 3	4.3	6.4	7.6	-2.3	2.8
Arm fat percentage (left)	4.2	16.6	16.8	4.1	-4.0
Long-standing illness, disability or infirmity	4.2	6.4	6.7	2.6	-2.5
Number of self-reported non-cancer illnesses	4.2	7.4	7.5	2.7	-2.7
Hair/balding pattern: Pattern 2	4.0	5.1	5.3	2.2	-2.3
Overall health rating	3.9	8.4	9.1	3.0	-2.8
Mean time to correctly identify matches	3.8	7.3	8.1	-2.6	2.8
Arm fat mass (left)	3.8	15.5	15.9	3.9	-4.0
Qualifications: CSEs or equivalent	3.6	4.7	5.5	2.0	-2.4
Frequency of tiredness / lethargy in last 2 weeks	3.6	5.9	7.0	2.6	-2.2
Arm fat percentage (right)	3.5	13.8	14.1	3.8	-3.7
Back pain experienced in last month	3.5	5.1	5.3	2.2	-2.3
Reaction Time	3.4	6.5	7.1	-2.4	2.7
Body mass index (BMI)	3.4	14.4	15.0	3.7	-3.9
Time employed in main current job	3.4	3.9	4.5	1.8	-2.1
Arm fat mass (right)	3.4	14.1	14.5	3.7	-3.8
Average weekly beer plus cider intake	3.4	4.9	5.0	2.2	-2.2
Supplements: Zinc	3.3	3.6	4.6	-1.6	2.1
Impedance of leg (right)	3.3	15.9	17.7	-3.8	4.2
Irritability	3.3	5.6	5.8	2.3	-2.4
Worry (Nagel 2018)	3.2	6.7	6.9	2.5	-2.6
Chest pain or discomfort	3.2	4.6	4.9	2.2	-2.1
Pain type(s) experienced in last month: Hip pain	3.2	4.0	4.1	2.0	-2.0
Trunk fat mass	3.0	12.9	13.0	3.6	-3.6
Heart attack/myocardial infarction (self-reported)	3.0	3.8	4.0	2.0	-1.9
Other serious medical condition/disability diagnosed by doctor	2.9	3.8	4.3	2.1	-1.8
Trunk fat percentage	2.9	11.5	12.4	3.5	-3.2
Heart attack	2.9	3.7	4.1	2.0	-1.8
Whole body fat mass	2.9	12.1	12.2	3.5	-3.5
Leg fat mass (left)	2.9	11.3	11.6	3.3	-3.4
Worry too long after embarrassment	2.8	4.7	4.9	2.2	-2.1
Depressed Affect (Nagel 2018)	2.7	5.8	6.4	2.5	-2.3
Ovarian Cancer	2.7	3.6	4.2	-1.8	2.0
Stomach or abdominal pain in last month	2.7	3.4	4.2	2.0	-1.6
Neuroticism score	2.7	5.6	5.7	2.4	-2.3
Asthma	2.7	5.3	6.3	2.5	-2.1
Commuting to job workplace: Car/motor vehicle	2.7	3.1	3.3	1.7	-1.8
Asthma (self-reported)	2.7	5.4	6.5	2.5	-2.1
Body fat percentage	2.6	10.3	10.9	3.3	-3.1
Leg fat-free mass (right)	2.6	13.9	15.9	3.5	-4.0
Ever had bowel cancer screening	2.6	3.0	3.3	1.8	-1.6
Leg predicted mass (right)	2.6	14.0	16.1	3.5	-4.0
Lung FEV1/FVC ratio	2.5	12.5	13.5	-3.7	3.4
Knee pain experienced in last month	2.5	3.8	4.2	2.0	-1.9
Diabetes (father)	2.4	2.9	3.2	1.6	-1.8
Had other major operations	2.3	2.8	2.9	1.7	-1.6
Hearing aid user	2.3	2.6	2.9	1.7	-1.5
Respiratory disease	2.2	5.0	5.8	2.4	-2.0
Weight	2.2	11.0	12.1	3.1	-3.5
Peak expiratory flow (PEF)	2.2	5.2	5.6	-2.4	2.2
Leg fat percentage (left)	2.2	8.0	8.2	2.9	-2.8
Depression (Nagel 2018)	2.1	3.1	3.9	2.0	-1.5
Relative age of first facial hair	2.1	4.2	5.0	-1.9	2.2
Leg fat-free mass (left)	2.1	11.1	13.0	3.0	-3.6
Impedance of leg (left)	2.1	10.0	12.0	-2.8	3.5
Leg predicted mass (left)	2.1	11.3	13.3	3.1	-3.6
Leg fat mass (right)	2.1	8.3	8.9	2.8	-3.0
Mood swings	2.1	3.8	4.1	2.0	-1.8
Systolic Blood Pressure	2.0	10.2	11.9	-3.4	2.9
Systolic blood pressure, automated reading	2.0	5.8	7.1	-2.7	2.1
Medication for hormone replacement therapy	2.0	2.2	2.4	1.4	-1.5
Taking other prescription medications	2.0	3.0	3.4	1.6	-1.8
Illnesses of siblings	2.0	2.8	2.9	1.7	-1.7
Neuroticism	1.9	4.6	4.6	2.1	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	3.2	1.8	-1.6
Vitamin and mineral supplements	1.8	2.5	2.8	-1.5	1.7
Pain all over the body in last month	1.8	2.0	2.3	1.5	-1.3
Worrier / anxious feelings	1.8	3.5	3.6	1.8	-1.9
Osteoarthritis (self-reported)	1.8	2.4	2.5	1.5	-1.6
Medication: Paracetamol	1.8	2.9	3.1	1.8	-1.6
Ulcerative Colitis (UC)	1.7	3.1	3.4	1.7	-1.8
Hand grip strength (left)	1.7	4.6	5.2	2.0	-2.3
Supplements: Glucosamine	1.7	2.2	3.2	1.1	-1.8
Waist circumference	1.7	6.3	6.5	2.5	-2.5
Medication: Seretide 50 evohaler	1.7	2.0	2.0	1.4	-1.4
Illnesses of father: Heart disease	1.7	2.4	2.5	1.5	-1.6
Average weekly red wine intake	1.7	2.5	2.8	-1.7	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	1.9	1.4	-1.3
Tinnitus: Yes, now most or all of the time	1.7	1.9	2.0	1.4	-1.4
Alzheimer’s Disease (including proxy)	1.6	2.3	2.5	1.6	-1.4
Schizophrenia (2014)	1.6	3.6	4.2	1.7	-2.1
Chronic bronchitis/emphysema (father)	1.6	1.9	2.5	1.6	-1.2
Medication: Paracetamol	1.6	2.7	2.8	1.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.0	2.5	1.6	-1.2
Ever had prostate specific antigen (PSA) test	1.6	1.9	2.3	-1.5	1.2
Fractured/broken bones in last 5 years	1.6	2.0	2.2	1.5	-1.4
Basal cell carcinoma (self-reported)	1.6	1.9	2.5	-1.6	1.2
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	2.5	1.5	-1.6
Hip circumference	1.5	6.3	7.2	2.3	-2.7
Medication: Cholesterol lowering	1.5	2.3	3.0	-1.7	1.3
Wheeze or whistling in the chest in last year	1.5	2.7	3.5	1.9	-1.4
Basal metabolic rate	1.5	8.5	10.3	2.6	-3.2
Age at First Birth	1.4	2.0	2.3	1.5	-1.3
Primary Biliary Cirrhosis	1.4	2.0	2.2	1.5	-1.3
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	1.9	1.4	-1.2
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	2.1	-1.2	1.4
Alcohol intake versus 10 years previously	1.4	2.1	2.4	1.4	-1.5
Type 2 Diabetes (T2D) (2012)	1.3	1.5	1.7	1.1	-1.3
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	1.7	-1.3	1.0
Fed-up feelings	1.3	2.4	2.9	1.7	-1.4
Leg fat percentage (right)	1.3	4.6	4.7	2.1	-2.2
Medication for pain relief, constipation, heartburn	1.3	2.1	2.2	-1.5	1.5
Angina (self-reported)	1.3	1.7	2.0	1.4	-1.2
Arm predicted mass (right)	1.3	6.7	8.4	2.2	-2.9
Commuting to job workplace: Cycle	1.3	1.6	1.7	-1.3	1.3
Heart disease (siblings)	1.3	1.6	1.6	-1.3	1.2
Body Mass Index (BMI) (2010)	1.2	1.7	1.9	1.4	-1.2
Hand grip strength (right)	1.2	3.3	3.6	1.7	-1.9
Maternal smoking around birth	1.2	1.7	1.7	1.3	-1.3
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	1.6	1.1	-1.3
Father’s age at death	1.2	1.6	1.6	-1.3	1.2
Exposure to tobacco smoke at home	1.2	1.4	1.5	-1.1	1.2
Arm fat-free mass (right)	1.2	6.0	7.7	2.1	-2.8
Whole body fat-free mass	1.2	6.9	8.8	2.2	-3.0
Whole body water mass	1.2	6.6	8.5	2.2	-2.9
Illnesses of father: High blood pressure	1.2	1.5	1.6	1.2	-1.3
Angina	1.1	1.4	1.6	1.3	-1.1
Exposure to tobacco smoke outside home	1.1	1.5	1.8	-1.1	1.3
Mother’s age at death	1.1	1.3	1.5	-1.2	1.1
Impedance of whole body	1.1	5.4	6.9	-2.0	2.6
Bipolar Disorder or Schizophrenia	1.0	2.4	2.8	1.4	-1.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	1.4	-1.2	1.0
Supplements: Vitamin C	1.0	1.2	1.4	1.2	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.2	-1.1	1.1
Commuting to job workplace: Public transport	1.0	1.2	1.4	1.2	-1.0
Schizophrenia (2018)	0.9	1.9	2.1	1.3	-1.4
Alzheimer’s Disease (in mother)	0.9	1.1	1.3	1.1	-0.9
Neuroticism (2016)	0.9	1.3	1.4	1.1	-1.2
Hypothyroidism (self reported)	0.9	2.0	2.5	1.6	-1.2
Hearing difficulty/problems: Yes	0.9	1.4	1.7	-1.0	1.3
Shortness of breath walking on level ground	0.9	1.1	1.4	1.2	-0.9
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.2	1.0	-1.1
Arm fat-free mass (left)	0.9	4.4	5.8	1.7	-2.4
Myopia	0.9	1.3	1.8	1.3	-0.9
Arm predicted mass (left)	0.9	4.4	5.8	1.7	-2.4
Triglycerides	0.8	1.3	1.4	1.2	-1.1
Allergy or Eczema	0.8	2.2	2.3	-1.4	1.5
Impedance of arm (right)	0.8	3.9	5.0	-1.7	2.2
Falls in the last year	0.8	1.0	1.3	1.1	-0.9
Pulse rate	0.8	1.3	1.4	1.2	-1.1
Suffer from ‘nerves’	0.8	1.2	1.4	1.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	1.0	-0.9	1.0
Wears glasses or contact lenses	0.8	1.0	1.3	-0.8	1.1
Medication: Bendroflumethiazide	0.8	1.2	1.9	-1.4	0.7
Number of treatments/medications taken	0.7	1.3	1.7	1.0	-1.3
Medication: Co-codamol	0.7	0.8	0.9	0.9	-0.8
Townsend deprivation index at recruitment	0.7	1.0	1.2	-0.9	1.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.0	0.7	-1.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.0	-0.9	1.0
Allergy	0.7	1.5	1.7	-1.3	1.1
Blood clot in the leg (DVT)	0.7	1.0	1.0	1.0	-1.0
Headache pain in last month	0.7	1.1	1.3	1.1	-1.0
Eye problems/disorders: None of the above	0.7	0.8	1.0	1.0	-0.7
Heart disease (mother)	0.7	0.9	1.2	0.7	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.2	-0.7	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.0	-0.8	1.0
Commuting to job workplace: Walk	0.7	0.7	0.7	-0.8	0.8
Medication for cholesterol	0.7	1.0	1.5	-0.7	1.2
Miserableness	0.7	1.2	1.5	1.2	-1.0
Age started oral contraceptive pill	0.7	0.8	0.9	-0.9	0.9
Alzheimer’s Disease (in father)	0.6	0.6	0.9	0.9	-0.6
Breast Cancer	0.6	1.5	2.0	1.4	-1.0
Tanning	0.6	6.8	7.6	-2.8	2.5
Severe depression (siblings)	0.6	0.7	0.7	0.9	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	1.3	1.1	-0.7
Had menopause	0.6	0.8	0.8	-0.9	0.9
Trunk fat-free mass	0.6	3.5	5.0	1.4	-2.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.0	1.0	-1.0
Chronic bronchitis/emphysema (mother)	0.6	0.7	0.8	0.9	-0.8
Average weekly champagne plus white wine intake	0.6	0.8	0.8	-0.9	0.9
Medication: Blood pressure	0.6	1.2	1.7	0.8	-1.3
Medication: Lisinopril	0.6	0.8	1.0	0.8	-1.0
Irritable Bowel Disease (IBD)	0.5	1.2	1.3	1.1	-1.1
Fasting Glucose	0.5	0.5	0.7	-0.8	0.6
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.3	0.7	-1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	0.9	0.7	-1.0
Multivitamins +/- minerals	0.5	0.7	0.9	0.7	-0.9
Medication: Atenolol	0.5	0.6	1.0	0.5	-1.0
Medication: Simvastatin	0.5	0.7	1.1	-1.1	0.5
Trunk predicted mass	0.5	2.9	4.2	1.2	-2.0
Loud music exposure frequency	0.5	0.6	0.7	-0.7	0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.2	1.1	-0.7
Medication: Allopurinol	0.5	0.6	0.8	-0.7	0.9
Eye problems/disorders: Cataract	0.5	0.6	0.9	-1.0	0.5
Bipolar Disorder (2018)	0.4	0.6	0.8	0.7	-0.9
Blood White Count	0.4	2.8	3.2	1.6	-1.8
Cardiovascular Disease	0.4	1.2	1.7	0.8	-1.3
Hearing difficulty/problems with background noise	0.4	0.7	1.2	-0.4	1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.0	-1.4	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.4	0.5	0.7	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	1.7	-1.3	0.8
Breastfed as a baby	0.4	0.5	0.6	-0.7	0.8
Pulse wave reflection index	0.4	0.5	0.7	-0.5	0.8
Number of full brothers	0.4	0.6	0.7	-0.6	0.8
Age at first live birth	0.4	0.6	1.0	1.0	-0.6
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.8	0.9	-0.4
Age at last live birth	0.4	0.6	0.9	1.0	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.8	0.9	-0.6
Mineral and other dietary supplements	0.4	0.6	0.9	0.9	-0.6
Pack years of smoking	0.4	0.6	0.7	-0.7	0.8
Verbal and Numeric Reasoning (VNR)	0.3	0.7	0.7	0.8	-0.8
Bipolar Disorder (2011)	0.3	0.3	0.4	0.6	-0.5
LDL Cholesterol	0.3	0.4	0.6	0.8	-0.5
Ulcerative Colitis	0.3	0.5	0.6	0.6	-0.8
Qualifications: None of the above	0.3	0.7	0.9	-0.7	0.9
Diabetes (self-reported)	0.3	0.4	0.5	-0.7	0.5
Noisy workplace	0.3	0.4	0.5	0.6	-0.7
Impedance of arm (left)	0.3	1.5	2.1	-1.0	1.4
High blood pressure (siblings)	0.3	0.4	0.5	-0.7	0.7
Neck or shoulder pain in last month	0.3	0.4	0.4	0.6	-0.6
Alcohol intake frequency.	0.3	0.8	0.9	0.8	-1.0
Ever smoked	0.3	0.5	0.7	-0.5	0.8
Number of operations (self-reported)	0.3	0.5	0.7	0.8	-0.5
Cholesterol lowering medication	0.3	0.5	0.6	0.5	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.4	0.6	-0.6
Coronary Artery Disease (CAD)	0.2	0.3	0.3	0.6	-0.4
Crohns Disease (2012)	0.2	0.3	0.3	-0.6	0.5
Lupus	0.2	0.3	0.6	-0.8	0.3
Rheumatoid Arthritis	0.2	0.3	0.4	0.6	-0.5
Blood Platelet Count	0.2	2.5	2.9	1.4	-1.7
Blood Red Count	0.2	1.9	2.0	1.3	-1.4
Height	0.2	3.3	4.3	-2.1	1.5
Lung FVC	0.2	0.9	1.3	-1.1	0.8
Medication: Metformin	0.2	0.3	0.4	-0.7	0.4
Diabetes (mother)	0.2	0.3	0.4	-0.5	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.6	-0.8	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.2	-0.5	0.5
Length of working week for main job	0.2	0.2	0.3	0.3	-0.5
Hair/balding pattern: Pattern 4	0.2	0.5	0.7	-0.8	0.4
Birth weight of first child	0.2	0.4	0.5	-0.7	0.6
Forced vital capacity (FVC), Best measure	0.2	0.6	0.9	-1.0	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.4	-0.6	0.3
Emphysema/chronic bronchitis	0.2	0.3	0.3	-0.6	0.5
Pulse rate, automated reading	0.2	0.7	0.9	0.8	-1.0
Qualifications: nursing, teaching	0.2	0.3	0.4	0.4	-0.6
Unable to work because of sickness or disability	0.2	0.3	0.5	0.7	-0.4
Prostate Cancer	0.1	0.1	0.3	-0.5	0.1
HbA1C	0.1	0.1	0.1	-0.2	0.3
Blood Eosinophil Count	0.1	0.8	0.9	0.9	-0.9
Heel T-Score	0.1	0.8	1.1	0.7	-1.1
Waist Hip Ratio (WHR)	0.1	0.6	1.0	-0.5	1.0
Average weekly spirits intake	0.1	0.1	0.3	0.5	-0.1
Pack years adult smoking proportion	0.1	0.1	0.2	-0.2	0.4
Age when periods started (menarche)	0.1	0.3	0.4	0.7	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	-0.6	0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.3	0.4
Medication: Levothyroxine sodium	0.1	0.2	0.3	-0.3	0.6
Sitting height	0.1	0.6	1.0	-1.0	0.5
High blood pressure (mother)	0.1	0.1	0.1	-0.4	0.1
Number of incorrect matches in round	0.1	0.2	0.3	-0.6	0.1
Past tobacco smoking	0.1	0.2	0.2	0.3	-0.5
Forced vital capacity (FVC)	0.1	0.2	0.4	-0.6	0.2
Happiness	0.1	0.2	0.2	0.4	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	0.2	-0.4	0.4
Medication: Lansoprazole	0.1	0.1	0.2	-0.2	0.4
Prospective memory result	0.1	0.1	0.2	-0.1	0.4
Lung cancer (father)	0.1	0.1	0.1	-0.3	0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	0.1	-0.4
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	-0.1	0.4
Gout (self-reported)	0.1	0.1	0.1	-0.2	0.3
Medication: Amlodipine	0.1	0.1	0.1	-0.3	0.4
Birth weight	0.1	0.2	0.4	0.3	-0.6
Pulse wave peak to peak time	0.1	0.2	0.2	-0.4	0.4
Qualifications: College or University degree	0.1	0.4	0.5	-0.7	0.6
Medication: Ibuprofen	0.1	0.1	0.2	0.4	-0.3
Comparative height size at age 10	0.1	0.4	0.7	0.4	-0.8
Medication: Aspirin	0.1	0.1	0.1	0.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.2	-0.5	0.3
Diabetes diagnosed by doctor	0.1	0.2	0.3	-0.6	0.4
Breast cancer (self-reported)	0.1	0.1	0.2	0.2	-0.4
Financial situation satisfaction	0.1	0.1	0.2	-0.2	0.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	-0.5	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	-0.5	0.2
High cholesterol (Self-reported)	0.1	0.2	0.3	-0.6	0.2
Medication: Atorvastatin	0.1	0.1	0.1	0.2	-0.4
Alcohol drinker status: Never	0.1	0.1	0.1	0.4	-0.2
Diastolic blood pressure, automated reading	0.1	0.2	0.4	-0.6	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.6	-0.3	0.8
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	0.2	-0.5
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	-0.2	0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	-0.1	0.2
Crohns Disease (2017)	0.0	0.0	0.1	0.0	0.3
Major Depression (MDD)	0.0	0.0	0.1	0.1	0.3
Mean Putamen Volume	0.0	0.0	0.0	-0.1	0.2
HDL Cholesterol	0.0	0.0	0.0	-0.0	-0.1
Smoking Status	0.0	0.0	0.0	0.2	-0.1
Hair Pigment	0.0	0.2	0.3	0.5	-0.3
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	0.1	-0.0
Current tobacco smoking	0.0	0.0	0.0	0.2	0.2
Average weekly fortified wine intake	0.0	0.0	0.1	0.2	-0.1
Relative age voice broke	0.0	0.0	0.0	0.2	0.2
High blood pressure	0.0	0.1	0.1	-0.1	-0.3
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.1	-0.2	0.3
Mouth/teeth dental problems	0.0	0.1	0.1	0.1	-0.4
Medication: Ramipril	0.0	0.1	0.1	0.3	-0.2
Fluid intelligence score	0.0	0.1	0.1	-0.3	0.3
Number of live births	0.0	0.1	0.1	-0.2	0.3
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.1	-0.1
Depression (self-reported)	0.0	0.0	0.0	-0.1	0.2
Illnesses of mother	0.0	0.0	0.1	0.3	-0.1
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	0.1	-0.2
Standing height	0.0	0.1	0.1	-0.4	-0.1
Glaucoma (self-reported)	0.0	0.0	0.1	-0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.1	0.3	-0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	-0.1	0.2
Comparative body size at age 10	0.0	0.0	0.0	-0.0	-0.2
Number of children fathered	0.0	0.0	0.0	-0.0	-0.1
Medication: Blood pressure	0.0	0.0	0.0	-0.1	-0.1
Migraine (self-reported)	0.0	0.0	0.0	0.1	-0.2
Medication: Omeprazole	0.0	0.0	0.1	-0.1	-0.3
Number of full sisters	0.0	0.0	0.1	0.2	0.1
Had major operations	0.0	0.0	0.0	-0.0	0.0
Family relationship satisfaction	0.0	0.0	0.1	-0.1	-0.3
Hypertension (Self-reported)	0.0	0.0	0.1	-0.2	-0.2
Illnesses of siblings: Diabetes	0.0	0.1	0.1	-0.1	0.3
Smoking status: Previous	0.0	0.0	0.0	-0.1	0.1
Friendships satisfaction	0.0	0.0	0.0	0.2	-0.1
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.0	0.1
Medication: Aspirin	0.0	0.0	0.0	-0.1	-0.1
Medication: Gliclazide	0.0	0.0	0.0	-0.1	0.0
Smoking status: Current	0.0	0.1	0.1	0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.1	-0.4	-0.0
Ever taken oral contraceptive pill	0.0	0.0	0.0	-0.0	0.0
Ever depressed for a whole week	0.0	0.0	0.0	-0.1	0.0
Supplements: Calcium	0.0	0.0	0.0	-0.1	-0.1
Alcohol drinker status: Previous	0.0	0.0	0.1	-0.2	-0.2

Hub : Genes

CWC27

Models

Trait associations